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David Arnott

Research Profile

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Publications

TOP 3
Homer Pantua; Arvind H Patel; Qui T Phung; Kentaro Takeda; Mark Ultsch; Robert F Kelley; Mary Mathieu; David J Matthews; Krista McCutcheon; David Arnott; Alex Brown; Tommy K Cheung; Shailesh Date; Jingyu Diao; Charles Eigenbrot; Philip E Hass; Meredith Hazen; Jo-Anne Hongo; Sharookh B Kapadia
Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.
Tatiana Goncharov; Anita Izrael-Tomasevic; Donald Kirkpatrick; Kyle Niessen; Eugene Varfolomeev; David Arnott; Maria Cristina de Almagro; Kurt Deshayes; Anna V Fedorova; Domagoj Vucic
OTUB1 modulates c-IAP1 stability to regulate signalling pathways.
Michael T Lipari; Paul Moran; Andrew S Peterson; Tao Sai; Jianyong Wang; Jose Zavala-Solorio; Ganesh Kolumam; Monica Kong-Beltran; Joyce Lai; Wei Li; S Jack Lin; David Arnott; Anita Izrael-Tomasevic; Daniel Kirchhofer
Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.

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All Publications

2013: Homer Pantua; Arvind H Patel; Qui T Phung; Kentaro Takeda; Mark Ultsch; Robert F Kelley; Mary Mathieu; David J Matthews; Krista McCutcheon; David Arnott; Alex Brown; Tommy K Cheung; Shailesh Date; Jingyu Diao; Charles Eigenbrot; Philip E Hass; Meredith Hazen; Jo-Anne Hongo; Sharookh B Kapadia
Glycan shifting on hepatitis C virus (HCV) e2 glycoprotein is a mechanism for escape from broadly neutralizing antibodies.
Journal of molecular biology 2013;425(11):1899-914.
2013: Tatiana Goncharov; Anita Izrael-Tomasevic; Donald Kirkpatrick; Kyle Niessen; Eugene Varfolomeev; David Arnott; Maria Cristina de Almagro; Kurt Deshayes; Anna V Fedorova; Domagoj Vucic
OTUB1 modulates c-IAP1 stability to regulate signalling pathways.
The EMBO journal 2013;32(8):1103-14.
2012: Michael T Lipari; Paul Moran; Andrew S Peterson; Tao Sai; Jianyong Wang; Jose Zavala-Solorio; Ganesh Kolumam; Monica Kong-Beltran; Joyce Lai; Wei Li; S Jack Lin; David Arnott; Anita Izrael-Tomasevic; Daniel Kirchhofer
Furin-cleaved proprotein convertase subtilisin/kexin type 9 (PCSK9) is active and modulates low density lipoprotein receptor and serum cholesterol levels.
The Journal of biological chemistry 2012;287(52):43482-91.
2012: Yan Qu; David Arnott; James E Cupp; Laurie L Gilmour; Anita Izrael-Tomasevic; Nobuhiko Kayagaki; László Kömüves; Mohamed Lamkanfi; Jinfeng Liu; Salina Louie; Shahram Misaghi; Denise M Monack; Kim Newton; Xiaodong Huang
Phosphorylation of NLRC4 is critical for inflammasome activation.
Nature 2012;490(7421):539-42.
2012: Oscar W Huang; Sarah G Hymowitz; Nobuhiko Kayagaki; Xiaolei Ma; Till Maurer; Qui T Phung; Melissa A Starovasnik; JianPing Yin; David Arnott; Ivan Bosanac; Vishva M Dixit; Jeremy Flinders; Andrea G Cochran
Phosphorylation-dependent activity of the deubiquitinase DUBA.
Nature structural & molecular biology 2012;19(2):171-5.
2011: Alberto C Vitari; Ingrid E Wertz; Cindy Yee; David Arnott; Suzana S Couto; Ronald Ferrando; Dorothy M French; Wei-Qiang Gao; Jo-Anne Hongo; Kevin G Leong; Jinfeng Liu; Sankar Mohan; Kim Newton; Karen O'Rourke; Ajay Pandita; Lilian Phu; Rajesh Vij; Vishva M Dixit
COP1 is a tumour suppressor that causes degradation of ETS transcription factors.
Nature 2011;474(7351):403-6.
2011: Lilian Phu; Anita Izrael-Tomasevic; Marissa L Matsumoto; Daisy Bustos; Jasmin Dynek; Anna V Fedorova; Corey E Bakalarski; David Arnott; Kurt Deshayes; Vishva M Dixit; Robert F Kelley; Domagoj Vucic; Donald S Kirkpatrick
Improved quantitative mass spectrometry methods for characterizing complex ubiquitin signals.
Molecular & cellular proteomics : MCP 2011;10(5):M110.003756.
2009: Anita Izrael-Tomasevic; Lilian Phu; Qui T Phung; Jennie R Lill; David Arnott
Targeting interferon alpha subtypes in serum: a comparison of analytical approaches to the detection and quantitation of proteins in complex biological matrices.
Journal of proteome research 2009;8(6):3132-40.
2009: Shahram Misaghi; Søren Ottosen; Anita Izrael-Tomasevic; David Arnott; Mohamed Lamkanfi; James Lee; Jinfeng Liu; Karen O'Rourke; Xiaodong Huang; Angus C Wilson
Association of C-terminal ubiquitin hydrolase BRCA1-associated protein 1 with cell cycle regulator host cell factor 1.
Molecular and cellular biology 2009;29(8):2181-92.
2007: Nobuhiko Kayagaki; Qui Phung; Salina Chan; Ruchir Chaudhari; Casey Quan; Karen M O'Rourke; Michael Eby; Eric Pietras; Genhong Cheng; J. Fernando Bazan; Zemin Zhang; David Arnott; Xiaodong Huang
DUBA: a deubiquitinase that regulates type I interferon production.
Science (New York, N.Y.) 2007;318(5856):1628-32.
2007: Sahana Mollah; Ingrid E Wertz; Qui Phung; David Arnott; Xiaodong Huang; Jennie R Lill
Targeted mass spectrometric strategy for global mapping of ubiquitination on proteins.
Rapid communications in mass spectrometry : RCM 2007;21(20):3357-64.
2006: Cary D Austin; David A Lawrence; Andrew A Peden; Eugene Varfolomeev; Klara Totpal; Ann M De Mazière; Judith Klumperman; David Arnott; Victoria Pham; Richard H Scheller; Avi Ashkenazi
Death-receptor activation halts clathrin-dependent endocytosis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(27):10283-8.
2006: Victoria Pham; william james Henzel; David Arnott; Sarah Hymowitz; Wendy N Sandoval; Bao-Tran Truong; Henry Lowman; Jennie R Lill
De novo proteomic sequencing of a monoclonal antibody raised against OX40 ligand.
Analytical biochemistry 2006;352(1):77-86.
2005: Kelly M Loyet; John T Stults; David Arnott
Mass spectrometric contributions to the practice of phosphorylation site mapping through 2003: a literature review.
Molecular & cellular proteomics : MCP 2005;4(3):235-45.
2005: John T Stults; David Arnott
Proteomics.
Methods in enzymology 2005;402():245-89.
2004: David Dornan; Ingrid E Wertz; Harumi Shimizu; David Arnott; Gretchen D Frantz; Patrick Dowd; Karen O'Rourke; Hartmut Koeppen; Xiaodong Huang
The ubiquitin ligase COP1 is a critical negative regulator of p53.
Nature 2004;429(6987):86-92.
2004: Ingrid E Wertz; Karen M O'Rourke; Zemin Zhang; David Dornan; David Arnott; Raymond J Deshaies; Xiaodong Huang
Human De-etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase.
Science (New York, N.Y.) 2004;303(5662):1371-4.
2002: David Arnott; Adrianne Kishiyama; Elizabeth A Luis; Sarah G Ludlum; James C Marsters; John T Stults
Selective detection of membrane proteins without antibodies: a mass spectrometric version of the Western blot.
Molecular & cellular proteomics : MCP 2002;1(2):148-56.
2001: Frank Kischkel; David A Lawrence; A Tinel; Heidi LeBlanc; A Virmani; Peter Schow; A Gazdar; J Blenis; David Arnott; Avi Ashkenazi
Death receptor recruitment of endogenous caspase-10 and apoptosis initiation in the absence of caspase-8.
The Journal of biological chemistry 2001;276(49):46639-46.
2001: Kathleen M Champion; Julie C Nishihara; John C Joly; David Arnott
Similarity of the Escherichia coli proteome upon completion of different biopharmaceutical fermentation processes.
Proteomics 2001;1(9):1133-48.
1999: Kathleen M Champion; David Arnott; william james Henzel; S Hermes; S Weikert; John T Stults; Martin Vanderlaan; L Krummen
A two-dimensional protein map of Chinese hamster ovary cells.
Electrophoresis 1999;20(4-5):994-1000.
1998: David Arnott; william james Henzel; John T Stults
Rapid identification of comigrating gel-isolated proteins by ion trap-mass spectrometry.
Electrophoresis 1998;19(6):968-80.
1998: David Arnott; K L O'Connell; K L King; John T Stults
An integrated approach to proteome analysis: identification of proteins associated with cardiac hypertrophy.
Analytical biochemistry 1998;258(1):1-18.