Irina Guzhova

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Yurinskaya M M; Vinokurov M G; Zatsepina O G; Garbuz D G; Guzhova I V; Rozhkova E A; Suslikov A V; Karpov V L; Evgen'ev M B
Exogenous heat shock proteins (HSP70) significantly inhibit endotoxin-induced activation of human neutrophils.
Garbuz David G; Zatsepina Olga G; Przhiboro Andrey A; Yushenova Irina; Guzhova Irina V; Evgen'ev Michael B
Larvae of related Diptera species from thermally contrasting habitats exhibit continuous up-regulation of heat shock proteins and high thermotolerance.
Afanasyeva Elena A; Komarova Elena Yu; Larsson Lars-Gunnar; Bahram Fuad; Margulis Boris A; Guzhova Irina V
Drug-induced Myc-mediated apoptosis of cancer cells is inhibited by stress protein Hsp70.

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2009: Yurinskaya M M; Vinokurov M G; Zatsepina O G; Garbuz D G; Guzhova I V; Rozhkova E A; Suslikov A V; Karpov V L; Evgen'ev M B
Exogenous heat shock proteins (HSP70) significantly inhibit endotoxin-induced activation of human neutrophils.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian 2009;426():298-301.
2008: Garbuz David G; Zatsepina Olga G; Przhiboro Andrey A; Yushenova Irina; Guzhova Irina V; Evgen'ev Michael B
Larvae of related Diptera species from thermally contrasting habitats exhibit continuous up-regulation of heat shock proteins and high thermotolerance.
Molecular ecology 2008;17(21):4763-77.
2007: Afanasyeva Elena A; Komarova Elena Yu; Larsson Lars-Gunnar; Bahram Fuad; Margulis Boris A; Guzhova Irina V
Drug-induced Myc-mediated apoptosis of cancer cells is inhibited by stress protein Hsp70.
International journal of cancer. Journal international du cancer 2007;121(12):2615-21.
2007: Cetinkaya Cihan; Hultquist Anne; Su Yingtao; Wu Siqin; Bahram Fuad; Påhlman Sven; Guzhova Irina; Larsson Lars-Gunnar
Combined IFN-gamma and retinoic acid treatment targets the N-Myc/Max/Mad1 network resulting in repression of N-Myc target genes in MYCN-amplified neuroblastoma cells.
Molecular cancer therapeutics 2007;6(10):2634-41.
2006: Evdonin Anton L; Guzhova Irina V; Margulis Boris A; Medvedeva Natalia D
Extracellular heat shock protein 70 mediates heat stress-induced epidermal growth factor receptor transactivation in A431 carcinoma cells.
FEBS letters 2006;580(28-29):6674-8.
2006: Kustanova G A; Murashev A N; Guzhova I V; Margulis B A; Prokhorenko I R; Grachev S V; Evgen'ev M B
Protective effect of exogenous 70-kDa heat shock protein during endotoxic shock (sepsis).
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian 2006;411():504-7.
2006: Evdonin Anton L; Martynova Marina G; Bystrova Olga A; Guzhova Irina V; Margulis Boris A; Medvedeva Natalia D
The release of Hsp70 from A431 carcinoma cells is mediated by secretory-like granules.
European journal of cell biology 2006;85(6):443-55.
2006: Novoselova E G; Glushkova O V; Cherenkov D A; Parfenyuk S B; Novoselova T V; Lunin S M; Khrenov M O; Guzhova I V; Margulis B A; Fesenko E E
Production of heat shock proteins, cytokines, and nitric oxide in toxic stress.
Biochemistry. Biokhimii?a 2006;71(4):376-83.
2006: Guzhova Irina; Margulis Boris
Hsp70 chaperone as a survival factor in cell pathology.
International review of cytology 2006;254():101-49.
2006: Kustanova Gul'sara A; Murashev Arcady N; Karpov Vadim L; Margulis Boris A; Guzhova Irina V; Prokhorenko Izabella R; Grachev Sergei V; Evgen'ev Michael B
Exogenous heat shock protein 70 mediates sepsis manifestations and decreases the mortality rate in rats.
Cell stress & chaperones 2006;11(3):276-86.
2005: Novoselova Tatiana V; Margulis Boris A; Novoselov Sergey S; Sapozhnikov Alexander M; van der Spuy Jacqueline; Cheetham Michael E; Guzhova Irina V
Treatment with extracellular HSP70/HSC70 protein can reduce polyglutamine toxicity and aggregation.
Journal of neurochemistry 2005;94(3):597-606.
2005: Novoselov S S; Novoselova T V; Verbova M V; Margulis B A; Guzhova I V
[The balance between Hsp70 and its cochaperones Hdj1 and Bag1 determines its substrate-binding activity]
Tsitologiia 2005;47(3):220-9.
2005: Guzhova I V; Novoselov S S; Margulis B A
[Hsp70 chaperone and the prospects of its application in anticancer therapy]
Tsitologiia 2005;47(3):187-99.
2005: Yurinskaya Valentina; Goryachaya Tatyana; Guzhova Irina; Moshkov Alexey; Rozanov Yuriy; Sakuta Galina; Shirokova Anna; Shumilina Ekaterina; Vassilieva Irina; Lang Florian; Vereninov Alexey
Potassium and sodium balance in U937 cells during apoptosis with and without cell shrinkage.
Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology 2005;16(4-6):155-62.
2004: Mokrushin A A; Pavlinova L I; Guzhova I V; Margulis B A
Effects of exogenous heat shock protein (Hsp70) on glutaminergic synaptic transmission in rat olfactory cortex in vitro.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian 2004;395():118-20.
2004: Mokrushin A A; Pavlinova L I; Guzhova I V; Margulis B A
Heat-shock protein (Hsp70) protects glutamatergic synaptic transmission in cells of the rat olfactory cortex against acute anoxia in vitro.
Doklady biological sciences : proceedings of the Academy of Sciences of the USSR, Biological sciences sections / translated from Russian 2004;394():12-5.
2004: Komarova Elena Yu; Afanasyeva Elena A; Bulatova Marina M; Cheetham Michael E; Margulis Boris A; Guzhova Irina V
Downstream caspases are novel targets for the antiapoptotic activity of the molecular chaperone hsp70.
Cell stress & chaperones 2004;9(3):265-75.
2004: Novoselov S S; Novoselova T V; Moskaleva O S; Margulis B A; Guzhova I V
[Dynamics of chaperone complex Hdj1-Hsp70-Bag1 as a response of erythroleukemia K562 cells to heat stress]
Tsitologiia 2004;46(7):620-7.
2004: Komarova E Iu; Margulis B A; Guzhova I V
[The role of Hsp70 chaperone in the reaction of human leukemic cells to anticancer drugs]
Tsitologiia 2004;46(6):550-6.
2004: Novoselov S S; Verbova M V; Vasil'eva E V; Vorob'ëva N K; Margulis B A; Guzhova I V
[Expression of Hsp70 and Hdj1 chaperone proteins in human tumor cells]
Voprosy onkologii 2004;50(2):174-8.
2003: Flerov M A; Ordyan N E; Margulis B A; Guzhova I V; V'yushina A V; Pivina S G; Gerasimova I A
The use of HSP70 for prevention of consequences of unavoidable stress in rats.
Bulletin of experimental biology and medicine 2003;136(2):120-2.
2002: Efremova Sofia M; Margulis Boris A; Guzhova Irina V; Itskovich Valeria B; Lauenroth Stephanie; Müller Werner E G; Schröder Heinz C
Heat shock protein Hsp70 expression and DNA damage in Baikalian sponges exposed to model pollutants and wastewater from Baikalsk Pulp and Paper Plant.
Aquatic toxicology (Amsterdam, Netherlands) 2002;57(4):267-80.
2001: Guzhova I; Hultquist A; Cetinkaya C; Nilsson K; Påhlman S; Larsson L G
Interferon-gamma cooperates with retinoic acid and phorbol ester to induce differentiation and growth inhibition of human neuroblastoma cells.
International journal of cancer. Journal international du cancer 2001;94(1):97-108.
2001: Guzhova I; Kislyakova K; Moskaliova O; Fridlanskaya I; Tytell M; Cheetham M; Margulis B
In vitro studies show that Hsp70 can be released by glia and that exogenous Hsp70 can enhance neuronal stress tolerance.
Brain research 2001;914(1-2):66-73.
2000: Fridlianskaia I I; Demideov O N; Bulatova M M; Ignat'eva E V; Semkina A N; Guzhova I V; Margulis B A
[Induction of apoptosis in murine myeloma cells NS0/1, transfected with the gene for the basic heat shock protein HSP70i]
Tsitologiia 2000;42(11):1053-9.
2000: Guzhova I V; Lasunskaia E B; Nilsson K; Darieva Z A; Margulis B A
[Effect of heat shock on cell differentiation and apoptosis in U-937 cells]
Tsitologiia 2000;42(7):653-8.
2000: Guzhova I V; Margulis B A
[Induction and accumulation of HSP70 leads to formation of its complexes with other cell proteins]
Tsitologiia 2000;42(7):647-52.
2000: Margulis B A; Guzhova I V
[Stress proteins in eukaryotic cells]
Tsitologiia 2000;42(4):323-42.
1998: Guzhova I V; Arnholdt A C; Darieva Z A; Kinev A V; Lasunskaia E B; Nilsson K; Bozhkov V M; Voronin A P; Margulis B A
Effects of exogenous stress protein 70 on the functional properties of human promonocytes through binding to cell surface and internalization.
Cell stress & chaperones 1998;3(1):67-77.
1997: Guzhova I V; Darieva Z A; Melo A R; Margulis B A
Major stress protein Hsp70 interacts with NF-kB regulatory complex in human T-lymphoma cells.
Cell stress & chaperones 1997;2(2):132-9.
1997: Lasunskaia E B; Fridlianskaia I I; Guzhova I V; Bozhkov V M; Margulis B A
Accumulation of major stress protein 70kDa protects myeloid and lymphoid cells from death by apoptosis.
Apoptosis : an international journal on programmed cell death 1997;2(2):156-63.
1992: Guzhova I V; Margulis B A; Kaminskaya E V
Antibody against p58 surface antigen of RA-2 rat rhabdomyosarcoma cells inhibits their metastatic activity.
International journal of cancer. Journal international du cancer 1992;52(6):892-5.
1988: Guzhova I V; Margulis B A
[Removal of surface antigens and changes in metastatic potential of transplantable rat rhabdomyosarcoma RA-2 cells]
Eksperimental'nai?a onkologii?a 1988;10(5):31-2.

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Irina Guzhova

Research Profile (preview)

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