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Merja Haaparanta

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Anna Kirjavainen; Sarita Forsback; Tove J Grönroos; Merja Haaparanta; Laura Haavisto; Olof Solin
Electrophilic addition of chlorine monofluoride for PET tracers.
Olli Eskola; Sarita Forsback; Tove J Grönroos; Merja Haaparanta; Jan Kiss; Juhani Knuuti; Sami Länkimäki; Päivi Marjamäki; Alexandru Naum; Timo Savunen; Jörgen Bergman; Olof Solin
Novel electrophilic synthesis of 6-[¹⁸F]fluorodopamine and comprehensive biological evaluation.
Olli Eskola; Sarita Forsback; Tove J Grönroos; Merja Haaparanta; Pirkko Härkönen; Gaber Komar; Heikki Minn; Jörgen Bergman; Johanna Tuomela; Olof Solin
Tracer level electrophilic synthesis and pharmacokinetics of the hypoxia tracer [(18)F]EF5.

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2013: Anna Kirjavainen; Sarita Forsback; Tove J Grönroos; Merja Haaparanta; Laura Haavisto; Olof Solin
Electrophilic addition of chlorine monofluoride for PET tracers.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2013;15(2):131-5.
2012: Olli Eskola; Sarita Forsback; Tove J Grönroos; Merja Haaparanta; Jan Kiss; Juhani Knuuti; Sami Länkimäki; Päivi Marjamäki; Alexandru Naum; Timo Savunen; Jörgen Bergman; Olof Solin
Novel electrophilic synthesis of 6-[¹⁸F]fluorodopamine and comprehensive biological evaluation.
European journal of nuclear medicine and molecular imaging 2012;39(5):800-10.
2012: Olli Eskola; Sarita Forsback; Tove J Grönroos; Merja Haaparanta; Pirkko Härkönen; Gaber Komar; Heikki Minn; Jörgen Bergman; Johanna Tuomela; Olof Solin
Tracer level electrophilic synthesis and pharmacokinetics of the hypoxia tracer [(18)F]EF5.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2012;14(2):205-12.
2012: Sarita Forsback; Tove Grönroos; Merja Haaparanta; Päivi Marjamäki; Johanna Rokka; Jörgen Bergman; Olli Eskola; Olof Solin
[18F]CFT synthesis and binding to monoamine transporters in rats.
EJNMMI research 2012;2(1):3.
2011: Veronica Fagerholm; Merja Haaparanta; Mika Scheinin
α2-adrenoceptor regulation of blood glucose homeostasis.
Basic & clinical pharmacology & toxicology 2011;108(6):365-70.
2010: Pekka Jokinen; Noora Scheinin; Sargo Aalto; Kjell Någren; Nina Savisto; Riitta Parkkola; Johanna Rokka; Merja Haaparanta; Matias Röyttä; Juha O Rinne
[(11)C]PIB-, [(18)F]FDG-PET and MRI imaging in patients with Parkinson's disease with and without dementia.
Parkinsonism & related disorders 2010;16(10):666-70.
2010: Veronica Fagerholm; Kirsi K Mikkola; Tamiko Ishizu; Eveliina Arponen; Saila Kauhanen; Kjell Någren; Olof Solin; Pirjo Nuutila; Merja Haaparanta
Assessment of islet specificity of dihydrotetrabenazine radiotracer binding in rat pancreas and human pancreas.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1439-46.
2010: Päivi Marjamäki; Merja Haaparanta; Sarita Forsback; Veronica Fagerholm; Olli Eskola; Tove Grönroos; Teija Koivula; Olof Solin
Comparison of 2beta-carbomethoxy-3beta-(4-[18F]fluorophenyl)tropane and N-(3-[18F]fluoropropyl)-2beta-carbomethoxy-3beta-(4-fluorophenyl)nortropane, tracers for imaging dopamine transporter in rat.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2010;12(3):269-77.
2010: Jarna C Hannukainen; Kari K Kalliokoski; Ronald J M Borra; Antti Viljanen; Tuula Janatuinen; Urho M Kujala; Jaakko Kaprio; Olli J Heinonen; Tapio Viljanen; Merja Haaparanta; Patricia Iozzo; Riitta Parkkola; Pirjo Nuutila
Higher free fatty acid uptake in visceral than in abdominal subcutaneous fat tissue in men.
Obesity (Silver Spring, Md.) 2010;18(2):261-5.
2008: Jussi Koivunen; A Verkkoniemi; Sargo Aalto; A Paetau; J-P Ahonen; Matti Viitanen; Kjell Någren; J Rokka; Merja Haaparanta; Hannu Kalimo; Juha O Rinne
PET amyloid ligand [11C]PIB uptake shows predominantly striatal increase in variant Alzheimer's disease.
Brain : a journal of neurology 2008;131(Pt 7):1845-53.
2008: Veronica Fagerholm; Johanna Rokka; Leena Nyman; Jukka Sallinen; Jari Tiihonen; Erkki Tupala; Merja Haaparanta; Jarmo Hietala
Autoradiographic characterization of alpha(2C)-adrenoceptors in the human striatum.
Synapse (New York, N.Y.) 2008;62(7):508-15.
2008: Teija Koivula; Päivi Marjamäki; Merja Haaparanta; Veronica Fagerholm; Tove Grönroos; Tiina Lipponen; Outi Perhola; Jouko Vepsäläinen; Olof Solin
Ex vivo evaluation of N-(3-[18F]fluoropropyl)-2 beta-carbomethoxy-3 beta-(4-fluorophenyl)nortropane in rats.
Nuclear medicine and biology 2008;35(2):177-83.
2007: Jarna C Hannukainen; Pirjo Nuutila; Ronald Borra; Borra Ronald; Jaakko Kaprio; Urho M Kujala; Tuula Janatuinen; Olli Heinonen; Jukka Kapanen; Tapio Viljanen; Merja Haaparanta; Tapani Rönnemaa; Riitta Parkkola; Juhani Knuuti; Kari K Kalliokoski
Increased physical activity decreases hepatic free fatty acid uptake: a study in human monozygotic twins.
The Journal of physiology 2007;578(Pt 1):347-58.
2006: Iina Laitinen; Päivi Marjamäki; Merja Haaparanta; Nina Savisto; Jukka Laine; Sanna L Soini; Ian Wilson; Pia Leppänen; Seppo Ylä-Herttuala; Anne Roivainen; Juhani Knuuti
Non-specific binding of [18F]FDG to calcifications in atherosclerotic plaques: experimental study of mouse and human arteries.
European journal of nuclear medicine and molecular imaging 2006;33(12):1461-7.
2006: Eeva-Liisa Kämäräinen; Merja Haaparanta; Marja Siitari-Kauppi; Teija Koivula; Tiina Lipponen; Olof Solin
Analysis of 18F-labelled synthesis products on TLC plates: comparison of radioactivity scanning, film autoradiography, and a phosphoimaging technique.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2006;64(9):1043-7.
2006: Merja Haaparanta; Tove Grönroos; Olli Eskola; Jörgen Bergman; Olof Solin
Planar chromatographic analysis and quantification of short-lived radioactive metabolites from microdialysis fractions.
Journal of chromatography. A 2006;1108(1):136-9.
2005: Teemu Kalliokoski; Olli Simell; Merja Haaparanta; Tapio Viljanen; Olof Solin; Juhani Knuuti; Pirjo Nuutila
An autoradiographic study of [(18)F]FDG uptake to islets of Langerhans in NOD mouse.
Diabetes research and clinical practice 2005;70(3):217-24.
2005: Jarmo Hietala; Mikko J Nyman; Olli Eskola; Aki Laakso; Tove Grönroos; Vesa Oikonen; Jörgen Bergman; Merja Haaparanta; Sarita Forsback; Päivi Marjamäki; Pertti Lehikoinen; Michael Goldberg; Donald Burns; Terence G Hamill; Waisi Eng; Alexandre Coimbra; Richard Hargreaves; Olof Solin
Visualization and quantification of neurokinin-1 (NK1) receptors in the human brain.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005;7(4):262-72.
2005: Aki Laakso; Tiina Pohjalainen; Jörgen Bergman; Jaana Kajander; Merja Haaparanta; Olof Solin; Erkka Syvälahti; Jarmo Hietala
The A1 allele of the human D2 dopamine receptor gene is associated with increased activity of striatal L-amino acid decarboxylase in healthy subjects.
Pharmacogenetics and genomics 2005;15(6):387-91.
2004: Veronica Fagerholm; Tove Grönroos; Päivi Marjamäki; Tapio Viljanen; Mika Scheinin; Merja Haaparanta
Altered glucose homeostasis in alpha2A-adrenoceptor knockout mice.
European journal of pharmacology 2004;505(1-3):243-52.
2004: Olof Solin; Olli Eskola; Terence G Hamill; Jörgen Bergman; Pertti Lehikoinen; Tove Grönroos; Sarita Forsback; Merja Haaparanta; Tapio Viljanen; Christine Ryan; Raymond Gibson; Gerard Kieczykowski; Jarmo Hietala; Richard Hargreaves; H Donald Burns
Synthesis and characterization of a potent, selective, radiolabeled substance-P antagonist for NK1 receptor quantitation: ([18F]SPA-RQ).
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(6):373-84.
2004: Patricia Iozzo; R Lautamaki; F Geisler; Kirsi A Virtanen; Vesa Oikonen; Merja Haaparanta; H Yki-Jarvinen; Ele Ferrannini; Juhani Knuuti; Pirjo Nuutila
Non-esterified fatty acids impair insulin-mediated glucose uptake and disposition in the liver.
Diabetologia 2004;47(7):1149-56.
2004: Tove Grönroos; Lise Bentzen; Päivi Marjamäki; Rumi Murata; Michael R Horsman; Susanne Keiding; Olli Eskola; Merja Haaparanta; Heikki Minn; Olof Solin
Comparison of the biodistribution of two hypoxia markers [18F]FETNIM and [18F]FMISO in an experimental mammary carcinoma.
European journal of nuclear medicine and molecular imaging 2004;31(4):513-20.
2004: Arja Muhonen; Merja Haaparanta; Tove Grönroos; J Bergman; Juhani Knuuti; Susanna Hinkka; Risto-Pekka Happonen
Osteoblastic activity and neoangiogenesis in distracted bone of irradiated rabbit mandible with or without hyperbaric oxygen treatment.
International journal of oral and maxillofacial surgery 2004;33(2):173-8.
2004: Sarita Forsback; Riitta Niemi; Päivi Marjamäki; Olli Eskola; Jörgen Bergman; Tove Grönroos; Merja Haaparanta; Antti Haapalinna; Juha Rinne; Olof Solin
Uptake of 6-[18F]fluoro-L-dopa and [18F]CFT reflect nigral neuronal loss in a rat model of Parkinson's disease.
Synapse (New York, N.Y.) 2004;51(2):119-27.
2004: Merja Haaparanta; Tove Grönroos; Päivi Marjamäki; Olli Eskola; Jörgen Bergman; Robert Paul; Olof Solin
In vivo sampling for pharmacokinetic studies in small experimental animals: a combination of microdialysis, planar chromatography and digital autoradiography.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(1):27-33.
2004: Olli Eskola; Tove Grönroos; Jörgen Bergman; Merja Haaparanta; Päivi Marjamäki; Pertti Lehikoinen; Sarita Forsback; Oliver Langer; Françoise Hinnen; Frédéric Dollé; Christer Halldin; Olof Solin
A novel electrophilic synthesis and evaluation of medium specific radioactivity (1R,2S)-4-[18F]fluorometaraminol, a tracer for the assessment of cardiac sympathetic nerve integrity with PET.
Nuclear medicine and biology 2004;31(1):103-10.
2003: Merja Haaparanta; Robert Paul; Tove Grönroos; Jörgen Bergman; Eeva-Liisa Kämäräinen; Olof Solin
Microdialysis and 2-[18F]fluoro-2-deoxy-D-glucose (FDG): a study on insulin action on FDG transport, uptake and metabolism in rat muscle, liver and adipose tissue.
Life sciences 2003;73(11):1437-51.
2003: Päivi Marjamäki; Jörg Zessin; Olli Eskola; Tove Grönroos; Merja Haaparanta; Jörgen Bergman; Pertti Lehikoinen; Sarita Forsback; Peter Brust; Jörg Steinbach; Olof Solin
S-[18F]fluoromethyl-(+)-McN5652, a PET tracer for the serotonin transporter: evaluation in rats.
Synapse (New York, N.Y.) 2003;47(1):45-53.
2002: Aki Laakso; Harry Vilkman; Jörgen Bergman; Merja Haaparanta; Olof Solin; Erkka Syvälahti; Raimo K R Salokangas; Jarmo Hietala
Sex differences in striatal presynaptic dopamine synthesis capacity in healthy subjects.
Biological psychiatry 2002;52(7):759-63.
2002: Kirsi A Virtanen; Merja Haaparanta; Tove Grönroos; J Bergman; Olof Solin; Juha Rouru; Pirjo Nuutila; Risto Huupponen
2-[(18)F]fluoro-2-deoxy-D-glucose combined with microdialysis can be used for the comparison of tissue glucose metabolism in obese and lean rats.
Diabetes, obesity & metabolism 2002;4(1):60-8.
2001: Aki Laakso; Jörgen Bergman; Merja Haaparanta; Harry Vilkman; Olof Solin; Erkka Syvälahti; Jarmo Hietala
Decreased striatal dopamine transporter binding in vivo in chronic schizophrenia.
Schizophrenia research 2001;52(1-2):115-20.
2001: Anna Brück; Raija Portin; Arja B Lindell; A Laihinen; Jörgen Bergman; Merja Haaparanta; Olof Solin; Juha O Rinne
Positron emission tomography shows that impaired frontal lobe functioning in Parkinson's disease is related to dopaminergic hypofunction in the caudate nucleus.
Neuroscience letters 2001;311(2):81-4.
2001: Tove Grönroos; Olli Eskola; Kaisa Lehtiö; Heikki Minn; Päivi Marjamäki; Jörgen Bergman; Merja Haaparanta; Sarita Forsback; Olof Solin
Pharmacokinetics of [18F]FETNIM: a potential marker for PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(9):1397-404.
2001: Eija Sutinen; Sirkku Jyrkkiö; Tove Grönroos; Merja Haaparanta; Pertti Lehikoinen; Kjell Någren
Biodistribution of [11C] methylaminoisobutyric acid, a tracer for PET studies on system A amino acid transport in vivo.
European journal of nuclear medicine 2001;28(7):847-54.
2001: Elina Nurmi; HM Ruottinen; Jörgen Bergman; Merja Haaparanta; Olof Solin; Pirkko Sonninen; Juha O Rinne
Rate of progression in Parkinson's disease: a 6-[18F]fluoro-L-dopa PET study.
Movement disorders : official journal of the Movement Disorder Society 2001;16(4):608-15.
2001: Salla Lamusuo; Leena Jutila; Aarne Ylinen; Reetta Kälviäinen; Esa Mervaala; Merja Haaparanta; Satu Jääskeläinen; Kaarina Partanen; Matti Vapalahti; Juha Rinne
[18F]FDG-PET reveals temporal hypometabolism in patients with temporal lobe epilepsy even when quantitative MRI and histopathological analysis show only mild hippocampal damage.
Archives of neurology 2001;58(6):933-9.
2000: Onofre T DeJesus; Merja Haaparanta; Olof Solin; Robert J Nickles
6-fluoroDOPA metabolism in rat striatum: time course of extracellular metabolites.
Brain research 2000;877(1):31-6.
2000: Elina Nurmi; HM Ruottinen; Valtteri Kaasinen; Jörgen Bergman; Merja Haaparanta; Olof Solin; Juha O Rinne
Progression in Parkinson's disease: a positron emission tomography study with a dopamine transporter ligand [18F]CFT.
Annals of neurology 2000;47(6):804-8.
2000: A Laihinen; HM Ruottinen; Juha O Rinne; Merja Haaparanta; Jörgen Bergman; Olof Solin; M Koskenvuo; Reijo J Marttila; UK Rinne
Risk for Parkinson's disease: twin studies for the detection of asymptomatic subjects using [18F]6-fluorodopa PET.
Journal of neurology 2000;247 Suppl 2():II110-3.
2000: Juha O Rinne; Raija Portin; HM Ruottinen; Elina Nurmi; Jörgen Bergman; Merja Haaparanta; Olof Solin
Cognitive impairment and the brain dopaminergic system in Parkinson disease: [18F]fluorodopa positron emission tomographic study.
Archives of neurology 2000;57(4):470-5.
2000: Raimo K R Salokangas; Harry Vilkman; Tuula Ilonen; Tero Taiminen; Jörgen Bergman; Merja Haaparanta; Olof Solin; Anna Alanen; Erkka Syvälahti; Jarmo Hietala
High levels of dopamine activity in the basal ganglia of cigarette smokers.
The American journal of psychiatry 2000;157(4):632-4.
2000: Aki Laakso; Harry Vilkman; Birgitta Alakare; Merja Haaparanta; Jörgen Bergman; Olof Solin; J Peurasaari; Viljo Räkköläinen; Erkka Syvälahti; Jarmo Hietala
Striatal dopamine transporter binding in neuroleptic-naive patients with schizophrenia studied with positron emission tomography.
The American journal of psychiatry 2000;157(2):269-71.
2000: HM Ruottinen; Markku Partinen; Christer Hublin; Jörgen Bergman; Merja Haaparanta; Olof Solin; Juha O Rinne
An FDOPA PET study in patients with periodic limb movement disorder and restless legs syndrome.
Neurology 2000;54(2):502-4.
1999: Hanna Laine; C Katoh; Matti Luotolahti; Hannele Yki-Järvinen; Ilkka Kantola; Antti Jula; Teemu Takala; Ulla Ruotsalainen; H Iida; Merja Haaparanta; Pirjo Nuutila; Juhani Knuuti
Myocardial oxygen consumption is unchanged but efficiency is reduced in patients with essential hypertension and left ventricular hypertrophy.
Circulation 1999;100(24):2425-30.
1999: Juha O Rinne; HM Ruottinen; Jörgen Bergman; Merja Haaparanta; Pirkko Sonninen; Olof Solin
Usefulness of a dopamine transporter PET ligand [(18)F]beta-CFT in assessing disability in Parkinson's disease.
Journal of neurology, neurosurgery, and psychiatry 1999;67(6):737-41.
1999: Teemu Takala; Pirjo Nuutila; C Katoh; Matti Luotolahti; J Bergman; Maija Mäki; Vesa Oikonen; Ulla Ruotsalainen; Tove Grönroos; Merja Haaparanta; Jukka Kapanen; Juhani Knuuti
Myocardial blood flow, oxygen consumption, and fatty acid uptake in endurance athletes during insulin stimulation.
The American journal of physiology 1999;277(4 Pt 1):E585-90.
1999: Anu K Turpeinen; Teemu Takala; Pirjo Nuutila; T Axelin; Matti Luotolahti; Merja Haaparanta; Jörgen Bergman; Helena Hämäläinen; H Iida; M Mäki; M I J Uusitupa; Juhani Knuuti
Impaired free fatty acid uptake in skeletal muscle but not in myocardium in patients with impaired glucose tolerance: studies with PET and 14(R,S)-[18F]fluoro-6-thia-heptadecanoic acid.
Diabetes 1999;48(6):1245-50.
1999: JM Nuutinen; Heikki Minn; J Bergman; Merja Haaparanta; U Ruotasalainen; Hanna Laine; J Knuuti
Uncoupling of fatty acid and glucose metabolism in malignant lymphoma: a PET study.
British journal of cancer 1999;80(3-4):513-8.
1999: Juha O Rinne; Jörgen Bergman; HM Ruottinen; Merja Haaparanta; E Eronen; Vesa Oikonen; Pirkko Sonninen; Olof Solin
Striatal uptake of a novel PET ligand, [18F]beta-CFT, is reduced in early Parkinson's disease.
Synapse (New York, N.Y.) 1999;31(2):119-24.
1999: Jarmo Hietala; Erkka Syvälahti; Harry Vilkman; K Vuorio; Viljo Räkköläinen; Jörgen Bergman; Merja Haaparanta; Olof Solin; M Kuoppamäki; E Eronen; Ulla Ruotsalainen; Raimo K R Salokangas
Depressive symptoms and presynaptic dopamine function in neuroleptic-naive schizophrenia.
Schizophrenia research 1999;35(1):41-50.
1999: H Suhonen-Polvi; Tarja Varho; Liisa Metsähonkala; L Haataja; Ulla Ruotsalainen; Merja Haaparanta; Jörgen Bergman; Olof Solin; Tuula Aärimaa; Irma E Holopainen; Leena Vainionpää; Tuula Manner; Satu Jääskeläinen; Martin Renlund; Matti Sillanpää; Pertti Aula
Increased brain glucose utilization in Salla disease (free sialic acid storage disorder).
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(1):12-8.
1998: Maija Mäki; Merja Haaparanta; Pirjo Nuutila; Vesa Oikonen; Matti Luotolahti; Olli Eskola; Juhani Knuuti
Free fatty acid uptake in the myocardium and skeletal muscle using fluorine-18-fluoro-6-thia-heptadecanoic acid.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(8):1320-7.
1998: Tapio Utriainen; Teemu Takala; Matti Luotolahti; Tapani Rönnemaa; Hanna Laine; Ulla Ruotsalainen; Merja Haaparanta; Pirjo Nuutila; Hannele Yki-Järvinen
Insulin resistance characterizes glucose uptake in skeletal muscle but not in the heart in NIDDM.
Diabetologia 1998;41(5):555-9.
1998: Aki Laakso; Jörgen Bergman; Merja Haaparanta; Harry Vilkman; Olof Solin; Jarmo Hietala
[18F]CFT [(18F)WIN 35,428], a radioligand to study the dopamine transporter with PET: characterization in human subjects.
Synapse (New York, N.Y.) 1998;28(3):244-50.
1998: Hanna Laine; H Yki-Jarvinen; O Kirvela; Tuula Tolvanen; Maria Raitakari; Olof Solin; Merja Haaparanta; Juhani Knuuti; Pirjo Nuutila
Insulin resistance of glucose uptake in skeletal muscle cannot be ameliorated by enhancing endothelium-dependent blood flow in obesity.
The Journal of clinical investigation 1998;101(5):1156-62.
1998: Hanna Laine; Juhani Knuuti; Ulla Ruotsalainen; Maria Raitakari; H Iida; Jukka Kapanen; Olli A Kirvelä; Merja Haaparanta; Hannele Yki-Järvinen; Pirjo Nuutila
Insulin resistance in essential hypertension is characterized by impaired insulin stimulation of blood flow in skeletal muscle.
Journal of hypertension 1998;16(2):211-9.
1997: Heikki Minn; M Lapela; Pekka Klemi; Reidar Grénman; S Leskinen; Paula Lindholm; Jörgen Bergman; E Eronen; Merja Haaparanta; H Joensuu
Prediction of survival with fluorine-18-fluoro-deoxyglucose and PET in head and neck cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1997;38(12):1907-11.
1997: Salla Lamusuo; HM Ruottinen; J Knuuti; R Härkönen; Ulla Ruotsalainen; Jörgen Bergman; Merja Haaparanta; Olof Solin; Esa Mervaala; U Nousiainen; Satu Jääskeläinen; Aarne Ylinen; Reetta Kälviäinen; J K Rinne; Matti Vapalahti; Juha O Rinne
Comparison of [18F]FDG-PET, [99mTc]-HMPAO-SPECT, and [123I]-iomazenil-SPECT in localising the epileptogenic cortex.
Journal of neurology, neurosurgery, and psychiatry 1997;63(6):743-8.
1997: HM Ruottinen; Juha O Rinne; Vesa Oikonen; JR Bergman; Merja Haaparanta; Olof Solin; Ulla Ruotsalainen; UK Rinne
Striatal 6-[18F]fluorodopa accumulation after combined inhibition of peripheral catechol-O-methyltransferase and monoamine oxidase type B: differing response in relation to presynaptic dopaminergic dysfunction.
Synapse (New York, N.Y.) 1997;27(4):336-46.
1997: Maija Mäki; Merja Haaparanta; Matti Luotolahti; Pirjo Nuutila; L M Voipio-Pulkki; JR Bergman; Olof Solin; Juhani Knuuti
Fatty acid uptake is preserved in chronically dysfunctional but viable myocardium.
The American journal of physiology 1997;273(5 Pt 2):H2473-80.
1997: M Mäki; Pirjo Nuutila; Hanna Laine; L M Voipio-Pulkki; Merja Haaparanta; Olof Solin; Juhani Knuuti
Myocardial glucose uptake in patients with NIDDM and stable coronary artery disease.
Diabetes 1997;46(9):1491-6.
1997: Tapio Utriainen; Pirjo Nuutila; Teemu Takala; Paolo Vicini; Ulla Ruotsalainen; Tapani Rönnemaa; Tuula Tolvanen; Maria Raitakari; Merja Haaparanta; Olli A Kirvelä; C Cobelli; Hannele Yki-Järvinen
Intact insulin stimulation of skeletal muscle blood flow, its heterogeneity and redistribution, but not of glucose uptake in non-insulin-dependent diabetes mellitus.
The Journal of clinical investigation 1997;100(4):777-85.
1997: A Kinnala; Pirjo Nuutila; Ulla Ruotsalainen; Mika Teräs; Jörgen Bergman; Merja Haaparanta; Olof Solin; Heikki Korvenranta; Tuula Aärimaa; U Wegelius; Pentti Kero; H Suhonen-Polvi
Cerebral metabolic rate for glucose after neonatal hypoglycaemia.
Early human development 1997;49(1):63-72.
1997: HM Ruottinen; Juha O Rinne; Merja Haaparanta; Olof Solin; Jörgen Bergman; Vesa Oikonen; I Järvelä; Pirkko Santavuori
[18F]fluorodopa PET shows striatal dopaminergic dysfunction in juvenile neuronal ceroid lipofuscinosis.
Journal of neurology, neurosurgery, and psychiatry 1997;62(6):622-5.
1997: Irma E Holopainen; Nina Lundbom; E L Metsähonkala; Markku Komu; Pirkko Sonninen; Merja Haaparanta; JR Bergman; M L Sillanpää
Temporal lobe pathology in epilepsy: proton magnetic resonance spectroscopy and positron emission tomography study.
Pediatric neurology 1997;16(2):98-104.
1997: Kimmo Malminiemi; Hanna Laine; Juhani Knuuti; Ulla Ruotsalainen; Vesa Oikonen; Merja Haaparanta; Pirjo Nuutila
Acute effects of celiprolol on muscle blood flow and insulin sensitivity: studies using [15O]-water, [18F]-fluorodeoxyglucose and positron emission tomography.
European journal of clinical pharmacology 1997;52(1):19-26.
1996: Maria Raitakari; Pirjo Nuutila; Ulla Ruotsalainen; Hanna Laine; Mika Teräs; H Iida; Sari Mäkimattila; Tapio Utriainen; Vesa Oikonen; Hannu Sipilä; Merja Haaparanta; Olof Solin; U Wegelius; Juhani Knuuti; Hannele Yki-Järvinen
Evidence for dissociation of insulin stimulation of blood flow and glucose uptake in human skeletal muscle: studies using [15O]H2O, [18F]fluoro-2-deoxy-D-glucose, and positron emission tomography.
Diabetes 1996;45(11):1471-7.
1996: Merja Haaparanta; Jörgen Bergman; Aki Laakso; Jarmo Hietala; Olof Solin
[18F]CFT ([18F]WIN 35,428), a radioligand to study the dopamine transporter with PET: biodistribution in rats.
Synapse (New York, N.Y.) 1996;23(4):321-7.
1996: A Kinnala; H Suhonen-Polvi; Tuula Aärimaa; Pentti Kero; Heikki Korvenranta; Ulla Ruotsalainen; Jörgen Bergman; Merja Haaparanta; Olof Solin; Pirjo Nuutila; U Wegelius
Cerebral metabolic rate for glucose during the first six months of life: an FDG positron emission tomography study.
Archives of disease in childhood. Fetal and neonatal edition 1996;74(3):F153-7.
1996: Maija Mäki; Matti Luotolahti; Pirjo Nuutila; H Iida; Liisa-Maria Voipio-Pulkki; Ulla Ruotsalainen; Merja Haaparanta; Olof Solin; Jaakko Hartiala; R Härkönen; Juhani Knuuti
Glucose uptake in the chronically dysfunctional but viable myocardium.
Circulation 1996;93(9):1658-66.
1996: Ulla Ruotsalainen; H Suhonen-Polvi; E Eronen; A Kinnala; Jörgen Bergman; Merja Haaparanta; Mika Teräs; Olof Solin; U Wegelius
Estimated radiation dose to the newborn in FDG-PET studies.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(2):387-93.
1995: M Lapela; S Leskinen; Heikki Minn; Paula Lindholm; P J Klemi; Karl-Ove Söderström; Jörgen Bergman; Merja Haaparanta; Ulla Ruotsalainen; Olof Solin; Heikki Joensuu
Increased glucose metabolism in untreated non-Hodgkin's lymphoma: a study with positron emission tomography and fluorine-18-fluorodeoxyglucose.
Blood 1995;86(9):3522-7.
1995: Jarmo Hietala; Erkka Syvälahti; K Vuorio; V Räkköläinen; Jörgen Bergman; Merja Haaparanta; Olof Solin; M Kuoppamäki; Olli A Kirvelä; Ulla Ruotsalainen
Presynaptic dopamine function in striatum of neuroleptic-naive schizophrenic patients.
Lancet 1995;346(8983):1130-1.
1995: M Lapela; Reidar Grénman; T Kurki; Heikki Joensuu; S Leskinen; Paula Lindholm; Merja Haaparanta; Ulla Ruotsalainen; Heikki Minn
Head and neck cancer: detection of recurrence with PET and 2-[F-18]fluoro-2-deoxy-D-glucose.
Radiology 1995;197(1):205-11.
1995: Pirjo Nuutila; Maija Mäki; Hanna Laine; Juhani Knuuti; Ulla Ruotsalainen; Matti Luotolahti; Merja Haaparanta; Olof Solin; A Jula; V A Koivisto
Insulin action on heart and skeletal muscle glucose uptake in essential hypertension.
The Journal of clinical investigation 1995;96(2):1003-9.
1995: H Suhonen-Polvi; Ulla Ruotsalainen; A Kinnala; Jörgen Bergman; Merja Haaparanta; Mika Teräs; P M akel a; Olof Solin; U Wegelius
FDG-PET in early infancy: simplified quantification methods to measure cerebral glucose utilization.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1249-54.
1995: Juhani Knuuti; Maija Mäki; Hannele Yki-Järvinen; Liisa-Maria Voipio-Pulkki; R Härkönen; Merja Haaparanta; Pirjo Nuutila
The effect of insulin and FFA on myocardial glucose uptake.
Journal of molecular and cellular cardiology 1995;27(7):1359-67.
1995: Merja Haaparanta; R Paul; R Huovinen; Harry Kujari; Jörgen Bergman; Olof Solin; L Kangas
Pharmacokinetics and metabolism of 2-[18F]fluoro-2-deoxy-D-glucose (FDG) in mammary tumors of antiestrogen-treated rats.
Nuclear medicine and biology 1995;22(4):483-9.
1995: HM Ruottinen; Juha O Rinne; Ulla Ruotsalainen; J R Bergman; Vesa Oikonen; Merja Haaparanta; Olof Solin; A O Laihinen; UK Rinne
Striatal [18F]fluorodopa utilization after COMT inhibition with entacapone studied with PET in advanced Parkinson's disease.
Journal of neural transmission. Parkinson's disease and dementia section 1995;10(2-3):91-106.
1995: Pirjo Nuutila; Juhani Knuuti; Maija Mäki; Hanna Laine; Ulla Ruotsalainen; Mika Teräs; Merja Haaparanta; Olof Solin; Hannele Yki-Järvinen
Gender and insulin sensitivity in the heart and in skeletal muscles. Studies using positron emission tomography.
Diabetes 1995;44(1):31-6.
1994: Pirjo Nuutila; Juhani Knuuti; Maria Raitakari; Ulla Ruotsalainen; Mika Teräs; Liisa-Maria Voipio-Pulkki; Merja Haaparanta; Olof Solin; U Wegelius; Hannele Yki-Järvinen
Effect of antilipolysis on heart and skeletal muscle glucose uptake in overnight fasted humans.
The American journal of physiology 1994;267(6 Pt 1):E941-6.
1994: Juhani Knuuti; Hannele Yki-Järvinen; Liisa-Maria Voipio-Pulkki; Maija Mäki; Ulla Ruotsalainen; R Härkönen; Mika Teräs; Merja Haaparanta; Jörgen Bergman; Jaakko Hartiala
Enhancement of myocardial [fluorine-18]fluorodeoxyglucose uptake by a nicotinic acid derivative.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(6):989-98.
1994: G Blomqvist; R J Seitz; I Sjögren; Christer Halldin; Sharon Stone-Elander; L Widén; Olof Solin; Merja Haaparanta
Regional cerebral oxidative and total glucose consumption during rest and activation studied with positron emission tomography.
Acta physiologica Scandinavica 1994;151(1):29-43.
1994: Juhani Knuuti; M Saraste; Pirjo Nuutila; R Härkönen; U Wegelius; A Haapanen; Jörgen Bergman; Merja Haaparanta; T Savunen; Liisa-Maria Voipio-Pulkki
Myocardial viability: fluorine-18-deoxyglucose positron emission tomography in prediction of wall motion recovery after revascularization.
American heart journal 1994;127(4 Pt 1):785-96.
1993: Liisa-Maria Voipio-Pulkki; Pirjo Nuutila; Juhani Knuuti; Ulla Ruotsalainen; Merja Haaparanta; Mika Teräs; U Wegelius; V A Koivisto
Heart and skeletal muscle glucose disposal in type 2 diabetic patients as determined by positron emission tomography.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(12):2064-7.
1993: Paula Lindholm; S Leskinen-Kallio; Heikki Minn; Jörgen Bergman; Merja Haaparanta; Pertti Lehikoinen; Kjell Någren; Ulla Ruotsalainen; Mika Teräs; Heikki Joensuu
Comparison of fluorine-18-fluorodeoxyglucose and carbon-11-methionine in head and neck cancer.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1993;34(10):1711-6.
1993: H Suhonen-Polvi; Pentti Kero; Heikki Korvenranta; Ulla Ruotsalainen; Merja Haaparanta; Jörgen Bergman; O Simell; U Wegelius
Repeated fluorodeoxyglucose positron emission tomography of the brain in infants with suspected hypoxic-ischaemic brain injury.
European journal of nuclear medicine 1993;20(9):759-65.
1993: Pirjo Nuutila; Juhani Knuuti; Ulla Ruotsalainen; V A Koivisto; E Eronen; Mika Teräs; Jörgen Bergman; Merja Haaparanta; Liisa-Maria Voipio-Pulkki; J Viikari
Insulin resistance is localized to skeletal but not heart muscle in type 1 diabetes.
The American journal of physiology 1993;264(5 Pt 1):E756-62.
1993: Heikki Minn; S Leskinen-Kallio; Paula Lindholm; Jörgen Bergman; Ulla Ruotsalainen; Mika Teräs; Merja Haaparanta
[18F]fluorodeoxyglucose uptake in tumors: kinetic vs. steady-state methods with reference to plasma insulin.
Journal of computer assisted tomography 1993;17(1):115-23.
1992: Juhani Knuuti; Pirjo Nuutila; Ulla Ruotsalainen; M Saraste; R Härkönen; A Ahonen; Mika Teräs; Merja Haaparanta; U Wegelius; A Haapanen
Euglycemic hyperinsulinemic clamp and oral glucose load in stimulating myocardial glucose utilization during positron emission tomography.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1992;33(7):1255-62.
1992: Pirjo Nuutila; V A Koivisto; Juhani Knuuti; Ulla Ruotsalainen; Mika Teräs; Merja Haaparanta; Jörgen Bergman; Olof Solin; Liisa-Maria Voipio-Pulkki; U Wegelius
Glucose-free fatty acid cycle operates in human heart and skeletal muscle in vivo.
The Journal of clinical investigation 1992;89(6):1767-74.
1992: A Laihinen; Juha O Rinne; UK Rinne; Merja Haaparanta; Ulla Ruotsalainen; Jörgen Bergman; Olof Solin
[18F]-6-fluorodopa PET scanning in Parkinson's disease after selective COMT inhibition with nitecapone (OR-462).
Neurology 1992;42(1):199-203.
1991: H Suhonen-Polvi; Ulla Ruotsalainen; A Ahonen; Merja Haaparanta; K Aho; R Riikonen; Pentti Kero; Heikki Korvenranta; O Simell; U Wegelius
Positron emission tomography in asphyxiated infants. Preliminary studies of regional cerebral glucose metabolism using 18F-FDG.
Acta radiologica. Supplementum 1991;376():173.
1991: G Blomqvist; Sharon Stone-Elander; Christer Halldin; Per E Roland; C G Swahn; Merja Haaparanta; Olof Solin; M Lindqvist; L Widén
Cerebral glucose utilization measured by positron emission tomography. [1-11C]-D-glucose compared with [2-18F]-2-fluoro-2-deoxy-D-glucose.
Acta radiologica. Supplementum 1991;376():171-2.
1991: Juha O Rinne; A Laihinen; Kjell Någren; Jörgen Bergman; Merja Haaparanta; Olof Solin; Ulla Ruotsalainen; UK Rinne
Positron emission tomography of brain dopamine D-1 receptors with 11C-SCH 23390 in Parkinson's disease.
Acta radiologica. Supplementum 1991;376():152.
1991: A Laihinen; Juha O Rinne; Kjell Någren; Jörgen Bergman; Merja Haaparanta; Olof Solin; Ulla Ruotsalainen; UK Rinne
Positron emission tomography of brain dopamine D-2 receptors with 11C-raclopride in early Parkinson's disease.
Acta radiologica. Supplementum 1991;376():151.
1991: A Ahonen; Liisa-Maria Voipio-Pulkki; Ulla Ruotsalainen; S Parviainen; S L Ylinen; Merja Haaparanta; P Korkeila; U Wegelius
Myocardial viability estimated with 18F-FDG PET in patients with severe angina and 201Tl and 99mTc MIBI SPECT perfusion defects.
Acta radiologica. Supplementum 1991;376():135-6.
1990: Juha O Rinne; A Laihinen; Kjell Någren; Jörgen Bergman; Olof Solin; Merja Haaparanta; Ulla Ruotsalainen; UK Rinne
PET demonstrates different behaviour of striatal dopamine D-1 and D-2 receptors in early Parkinson's disease.
Journal of neuroscience research 1990;27(4):494-9.
1990: Joakim Tedroff; Sten-Magnus Aquilonius; A Laihinen; UK Rinne; Per Hartvig; J Anderson; Hans Lundqvist; Merja Haaparanta; O Solin; G Antoni
Striatal kinetics of [11C]-(+)-nomifensine and 6-[18F]fluoro-L-dopa in Parkinson's disease measured with positron emission tomography.
Acta neurologica Scandinavica 1990;81(1):24-30.
1989: L Kangas; Merja Haaparanta; R Paul; D Roeda; Hannu Sipilä
Biodistribution and scintigraphy of 11C-toremifene in rats bearing DMBA-induced mammary carcinoma.
Pharmacology & toxicology 1989;64(4):373-7.
1989: R Paul; K Aho; J Bergman; Merja Haaparanta; J Kulmala; A Reissell; Olof Solin
Imaging of rats with mammary cancer with two 2-deoxy-2-[18F]fluoro-D-hexoses.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1989;16(5):449-53.
1988: R d'Argy; R Paul; L Frankenberg; C G Stålnacke; Hans Lundqvist; L Kangas; Christer Halldin; Kjell Någren; D Roeda; Merja Haaparanta
Comparative double-tracer whole-body autoradiography: uptake of 11C-, 18F- and 3H-labeled compounds in rat tumors.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1988;15(5):577-85.
1987: R Paul; A Kiuru; K O Söderström; J Tuominen; R Johansson; Merja Haaparanta; D Roeda; Olof Solin
Organ and tumor distribution of (18F)-2-fluoro-2-deoxy-D-glucose in fasting and non-fasting rats.
Life sciences 1987;40(16):1609-16.
1986: E M Suolinna; Merja Haaparanta; R Paul; Pirkko L Härkönen; Olof Solin; Hannu Sipilä
Metabolism of 2-[18F]fluoro-2-deoxyglucose in tumor-bearing rats: chromatographic and enzymatic studies.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1986;13(5):577-81.
1986: R Paul; D Roeda; R Johansson; A Ahonen; Merja Haaparanta; Olof Solin; Hannu Sipilä
Scintigraphy with [18F]2-fluoro-2-deoxy-D-glucose of cancer patients.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1986;13(1):7-12.