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Erik Hack

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Enzyme-Linked Immunosorbent Assay

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Publications

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Mulder Sandra D; Heijst Johannes A; Mulder Cees; Martens Frans; Hack C Erik; Scheltens Philip; Blankenstein Marinus A; Veerhuis Robert
CSF levels of PSA and PSA-ACT complexes in Alzheimer's disease.
Schuitemaker Alie; Dik Miranda G; Veerhuis Robert; Scheltens Philip; Schoonenboom Niki S M; Hack C Erik; Blankenstein Marinus A; Jonker Cees
Inflammatory markers in AD and MCI patients with different biomarker profiles.
Verwey Nicolaas A; Veerhuis Robert; Twaalfhoven Harry A M; Wouters Dorine; Hoozemans Jeroen J M; Bollen Yves J M; Killestein Joep; Bibl Mirko; Wiltfang Jens; Hack C Erik; Scheltens Philip; Blankenstein Marinus A
Quantification of amyloid-beta 40 in cerebrospinal fluid.

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All Publications

2009: Mulder Sandra D; Heijst Johannes A; Mulder Cees; Martens Frans; Hack C Erik; Scheltens Philip; Blankenstein Marinus A; Veerhuis Robert
CSF levels of PSA and PSA-ACT complexes in Alzheimer's disease.
Annals of clinical biochemistry 2009;46(Pt 6):477-83.
2009: Schuitemaker Alie; Dik Miranda G; Veerhuis Robert; Scheltens Philip; Schoonenboom Niki S M; Hack C Erik; Blankenstein Marinus A; Jonker Cees
Inflammatory markers in AD and MCI patients with different biomarker profiles.
Neurobiology of aging 2009;30(11):1885-9.
2009: Verwey Nicolaas A; Veerhuis Robert; Twaalfhoven Harry A M; Wouters Dorine; Hoozemans Jeroen J M; Bollen Yves J M; Killestein Joep; Bibl Mirko; Wiltfang Jens; Hack C Erik; Scheltens Philip; Blankenstein Marinus A
Quantification of amyloid-beta 40 in cerebrospinal fluid.
Journal of immunological methods 2009;348(1-2):57-66.
2009: Diepenhorst Gwendolyn M P; van Gulik Thomas M; Hack C Erik
Complement-mediated ischemia-reperfusion injury: lessons learned from animal and clinical studies.
Annals of surgery 2009;249(6):889-99.
2009: van Dijk Annemieke; Krijnen Paul A J; Vermond Rob A; Pronk Amanda; Spreeuwenberg Marieke; Visser Frans C; Berney Richard; Paulus Walter J; Hack C Erik; van Milligen Florine J; Niessen Hans W M
Inhibition of type 2A secretory phospholipase A2 reduces death of cardiomyocytes in acute myocardial infarction.
Apoptosis : an international journal on programmed cell death 2009;14(6):753-63.
2008: Groeneveld A B Johan; Hack C Erik
The role of the innate immune response in hospital- versus community-acquired infection in febrile medical patients.
International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases 2008;12(6):660-70.
2008: Wagenaar-Bos Ineke G A; Drouet Christian; Aygören-Pursun Emel; Bork Konrad; Bucher Christoph; Bygum Anette; Farkas Henriette; Fust George; Gregorek Hanna; Hack C Erik; Hickey Alaco; Joller-Jemelka Helen I; Kapusta Maria; Kreuz Wolfhart; Longhurst Hilary; Lopez-Trascasa Margarita; Madalinski Kazimierz; Naskalski Jerzy; Nieuwenhuys Ed; Ponard Denise; Truedsson Lennart; Varga Lilian; Nielsen Erik Waage; Wagner Eric; Zingale Lorenza; Cicardi Marco; van Ham S Marieke
Functional C1-inhibitor diagnostics in hereditary angioedema: assay evaluation and recommendations.
Journal of immunological methods 2008;338(1-2):14-20.
2008: Meischl Christof; Buermans Henk P; Hazes Thierry; Zuidwijk Marian J; Musters René J P; Boer Christa; van Lingen Arthur; Simonides Warner S; Blankenstein Marinus A; Dupuy Corrine; Paulus Walter J; Hack C Erik; Ris-Stalpers Carrie; Roos Dirk; Niessen Hans W M
H9c2 cardiomyoblasts produce thyroid hormone.
American journal of physiology. Cell physiology 2008;294(5):C1227-33.
2008: Nijmeijer R; Meuwissen M; Krijnen P A J; van der Wal A; Piek J J; Visser C A; Hack C E; Niessen H W M
Secretory type II phospholipase A2 in culprit coronary lesions is associated with myocardial infarction.
European journal of clinical investigation 2008;38(4):205-10.
2008: Wouters Diana; Brouwer Mieke C; Daha Mohamed R; Hack C Erik
Studies on the haemolytic activity of circulating C1q-C3/C4 complexes.
Molecular immunology 2008;45(7):1893-9.
2008: Hemelaar Majoie; Kenemans Peter; Hack C Erik; Klipping Christine; van der Mooren Marius J
Hemostatic markers in healthy postmenopausal women during intranasal and oral hormone therapy: a randomized trial.
Menopause (New York, N.Y.) 2008;15(2):248-55.
2008: Verwey Nicolaas A; Schuitemaker Alie; van der Flier Wiesje M; Mulder Sandra D; Mulder Cees; Hack C Erik; Scheltens Philip; Blankenstein Marinus A; Veerhuis Robert
Serum amyloid p component as a biomarker in mild cognitive impairment and Alzheimer's disease.
Dementia and geriatric cognitive disorders 2008;26(6):522-7.
2007: Vermeulen Joost N; Prins Jan M; Bunnik Evelien; Hack C Erik; Jurriaans Suzanne; Miedema Frank; Lange Joep M A; Schuitemaker Hanneke
Intravenous immunoglobulin (IVIG) treatment for modulation of immune activation in human immunodeficiency virus type 1 infected therapy-naive individuals.
AIDS research and human retroviruses 2007;23(11):1348-53.
2007: Padilla Niubel Diaz; van Vliet Arlène K; Schoots Ivo G; Seron Mercedes Valls; Maas M Adrie; Peltenburg Esther E Posno; de Vries Annebeth; Niessen Hans W M; Hack C Erik; van Gulik Thomas M
C-reactive protein and natural IgM antibodies are activators of complement in a rat model of intestinal ischemia and reperfusion.
Surgery 2007;142(5):722-33.
2007: Kremer Hovinga J A; Zeerleder S; Kessler P; Romani de Wit T; van Mourik J A; Hack C E; ten Cate H; Reitsma P H; Wuillemin W A; Lämmle B
ADAMTS-13, von Willebrand factor and related parameters in severe sepsis and septic shock.
Journal of thrombosis and haemostasis : JTH 2007;5(11):2284-90.
2007: Govers-Riemslag J W P; Smid M; Cooper J A; Bauer K A; Rosenberg R D; Hack C E; Hamulyak K; Spronk H M H; Miller G J; ten Cate H
The plasma kallikrein-kinin system and risk of cardiovascular disease in men.
Journal of thrombosis and haemostasis : JTH 2007;5(9):1896-903.
2007: Kummer J A; Micheau O; Schneider P; Bovenschen N; Broekhuizen R; Quadir R; Strik M C M; Hack C E; Tschopp J
Ectopic expression of the serine protease inhibitor PI9 modulates death receptor-mediated apoptosis.
Cell death and differentiation 2007;14(8):1486-96.
2007: Biró E; Lok C A R; Hack C E; van der Post J A M; Schaap M C L; Sturk A; Nieuwland R
Cell-derived microparticles and complement activation in preeclampsia versus normal pregnancy.
Placenta 2007;28(8-9):928-35.
2007: Biró Eva; Nieuwland Rienk; Tak Paul P; Pronk Loes M; Schaap Marianne C L; Sturk Augueste; Hack C Erik
Activated complement components and complement activator molecules on the surface of cell-derived microparticles in patients with rheumatoid arthritis and healthy individuals.
Annals of the rheumatic diseases 2007;66(8):1085-92.
2007: Zwijnenburg Petra J G; van der Poll Tom; Florquin Sandrine; Polfliet Machteld M J; van den Berg Timo K; Dijkstra Christine D; Roord John J; Hack C Erik; van Furth A Marceline
C1 inhibitor treatment improves host defense in pneumococcal meningitis in rats and mice.
The Journal of infectious diseases 2007;196(1):115-23.
2007: Strik Merel C M; de Koning Pieter J A; Kleijmeer Monique J; Bladergroen Bellinda A; Wolbink Angela M; Griffith Janice M; Wouters Dorine; Fukuoka Yoshihiro; Schwartz Lawrence B; Hack C Erik; van Ham S Marieke; Kummer J Alain
Human mast cells produce and release the cytotoxic lymphocyte associated protease granzyme B upon activation.
Molecular immunology 2007;44(14):3462-72.
2007: Choi Goda; Soeters Maarten R; Farkas Henriette; Varga Lilian; Obtulowicz Krystyna; Bilo Barbara; Porebski Greg; Hack C Erik; Verdonk René; Nuijens Jan; Levi Marcel
Recombinant human C1-inhibitor in the treatment of acute angioedema attacks.
Transfusion 2007;47(6):1028-32.
2007: Pijnenburg Yolande A L; Janssen John C; Schoonenboom Niki S M; Petzold Axel; Mulder Cees; Stigbrand Torgny; Norgren Niklas; Heijst Hans; Hack C Erik; Scheltens Philip; Teunissen Charlotte E
CSF neurofilaments in frontotemporal dementia compared with early onset Alzheimer's disease and controls.
Dementia and geriatric cognitive disorders 2007;23(4):225-30.
2007: Zeerleder Sacha; Schroeder Verena; Lämmle Bernhard; Wuillemin Walter A; Hack C Erik; Kohler Hans Peter
Factor XIII in severe sepsis and septic shock.
Thrombosis research 2007;119(3):311-8.
2006: Wagenaar-Bos Ineke G A; Hack C Erik
Structure and function of C1-inhibitor.
Immunology and allergy clinics of North America 2006;26(4):615-32.
2006: Baidoshvili A; Krijnen P A J; Kupreishvili K; Ciurana C; Bleeker W; Nijmeijer R; Visser C A; Visser F C; Meijer C J L M; Stooker W; Eijsman L; van Hinsbergh V W M; Hack C E; Niessen H W M; Schalkwijk C G
N(epsilon)-(carboxymethyl)lysine depositions in intramyocardial blood vessels in human and rat acute myocardial infarction: a predictor or reflection of infarction?
Arteriosclerosis, thrombosis, and vascular biology 2006;26(11):2497-503.
2006: Keller T T; Choi D; Nagel C; Te Velthuis H; Gerdes V E A; Wareham N J; Bingham S A; Luben R; Hack C E; Reitsma P H; Levi M; Khaw K T; Boekholdt S M
Tissue factor serum levels and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.
Journal of thrombosis and haemostasis : JTH 2006;4(11):2391-6.
2006: Keller Tymen T; van Leuven Sander I; Meuwese Marijn C; Wareham Nicholas J; Luben Robert; Stroes Erik S; Hack C Erik; Levi Marcel; Khaw Kay-Tee; Boekholdt S Matthijs
Serum levels of mannose-binding lectin and the risk of future coronary artery disease in apparently healthy men and women.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2345-50.
2006: Tschopp Cornelia M; Spiegl Nicole; Didichenko Svetlana; Lutmann Werner; Julius Peter; Virchow J Christian; Hack C Erik; Dahinden Clemens A
Granzyme B, a novel mediator of allergic inflammation: its induction and release in blood basophils and human asthma.
Blood 2006;108(7):2290-9.
2006: Levi Marcel; Hack C Erik; van Oers Marinus H
Rituximab-induced elimination of acquired angioedema due to C1-inhibitor deficiency.
The American journal of medicine 2006;119(8):e3-5.
2006: Boekholdt S Matthijs; Hack C Erik; Sandhu Manjinder S; Luben Robert; Bingham Sheila A; Wareham Nicholas J; Peters Ron J G; Jukema J Wouter; Day Nicholas E; Kastelein John J P; Khaw Kay-Tee
C-reactive protein levels and coronary artery disease incidence and mortality in apparently healthy men and women: the EPIC-Norfolk prospective population study 1993-2003.
Atherosclerosis 2006;187(2):415-22.
2006: van Mirre Edwin; Breunis Willemijn B; Geissler Judy; Hack C Erik; de Boer Martin; Roos Dirk; Kuijpers Taco W
Neutrophil responsiveness to IgG, as determined by fixed ratios of mRNA levels for activating and inhibitory FcgammaRII (CD32), is stable over time and unaffected by cytokines.
Blood 2006;108(2):584-90.
2006: Krijnen Paul A J; Meischl Christof; Nijmeijer Remco; Visser Cees A; Hack C Erik; Niessen Hans W M
Inhibition of sPLA2-IIA, C-reactive protein or complement: new therapy for patients with acute myocardial infarction?
Cardiovascular & hematological disorders drug targets 2006;6(2):113-23.
2006: Sjöberg Andreas P; Trouw Leendert A; McGrath Fabian D G; Hack C Erik; Blom Anna M
Regulation of complement activation by C-reactive protein: targeting of the inhibitory activity of C4b-binding protein.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(12):7612-20.
2006: Verheijen Jan H; Huisman Linda G M; van Lent Natascha; Neumann Ulf; Paganetti Paolo; Hack C Erik; Bouwman Femke; Lindeman Jan; Bollen Edward L E M; Hanemaaijer Roeland
Detection of a soluble form of BACE-1 in human cerebrospinal fluid by a sensitive activity assay.
Clinical chemistry 2006;52(6):1168-74.
2006: Meischl C; Krijnen P A J; Sipkens J A; Cillessen S A G M; Muñoz I Gámez; Okroj M; Ramska M; Muller A; Visser C A; Musters R J P; Simonides W S; Hack C E; Roos D; Niessen H W M
Ischemia induces nuclear NOX2 expression in cardiomyocytes and subsequently activates apoptosis.
Apoptosis : an international journal on programmed cell death 2006;11(6):913-21.
2006: Levi Marcel; Choi Goda; Picavet Charles; Hack C Erik
Self-administration of C1-inhibitor concentrate in patients with hereditary or acquired angioedema caused by C1-inhibitor deficiency.
The Journal of allergy and clinical immunology 2006;117(4):904-8.
2006: Wouters Diana; Voskuyl Alexandre E; Molenaar Esmeralda T H; Dijkmans Ben A C; Hack C Erik
Evaluation of classical complement pathway activation in rheumatoid arthritis: measurement of C1q-C4 complexes as novel activation products.
Arthritis and rheumatism 2006;54(4):1143-50.
2006: Draaisma Anjo M; Hazekamp Mark G; Anes Nanning; Schoof Paul H; Hack C Erik; Sturk Augueste; Dion Robert A E
Phosphorylcholine coating of bypass systems used for young infants does not attenuate the inflammatory response.
The Annals of thoracic surgery 2006;81(4):1455-9.
2006: van der Zee P Marc; Biró Eva; Ko Yung; de Winter Robbert J; Hack C Erik; Sturk Augueste; Nieuwland Rienk
P-selectin- and CD63-exposing platelet microparticles reflect platelet activation in peripheral arterial disease and myocardial infarction.
Clinical chemistry 2006;52(4):657-64.
2006: McGrath Fabian D G; Brouwer Mieke C; Arlaud Gérard J; Daha Mohamed R; Hack C Erik; Roos Anja
Evidence that complement protein C1q interacts with C-reactive protein through its globular head region.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(5):2950-7.
2006: Ciurana Caroline L F; Hack C Erik
Competitive binding of pentraxins and IgM to newly exposed epitopes on late apoptotic cells.
Cellular immunology 2006;239(1):14-21.
2006: Heijnen B H M; Straatsburg I H; Padilla N D; Van Mierlo G J; Hack C E; Van Gulik T M
Inhibition of classical complement activation attenuates liver ischaemia and reperfusion injury in a rat model.
Clinical and experimental immunology 2006;143(1):15-23.
2006: Zeerleder Sacha; Schroeder Verena; Hack C Erik; Kohler Hans Peter; Wuillemin Walter A
TAFI and PAI-1 levels in human sepsis.
Thrombosis research 2006;118(2):205-12.
2005: Rowshani Ajda T; Strik Merel C M; Molenaar Rosalie; Yong Si-La; Wolbink Angela M; Bemelman Frederike J; Hack C Erik; Ten Berge Ineke J M
The granzyme B inhibitor SERPINB9 (protease inhibitor 9) circulates in blood and increases on primary cytomegalovirus infection after renal transplantation.
The Journal of infectious diseases 2005;192(11):1908-11.
2005: Mairuhu A T A; Setiati T E; Koraka P; Hack C E; Leyte A; Faradz S M H; ten Cate H; Brandjes D P M; Osterhaus A D M E; Reitsma P H; van Gorp E C M
Increased PAI-1 plasma levels and risk of death from dengue: no association with the 4G/5G promoter polymorphism.
Thrombosis journal 2005;3():17.
2005: de Bruin Eric C; Roem Dorina; Bulder Ingrid; Dieker Miranda; Voerman Gerard; Hack C Erik
Production, purification and characterisation of recombinant Fahsin, a novel antistasin-type proteinase inhibitor.
FEMS yeast research 2005;5(11):1069-77.
2005: Krijnen P A J; Cillessen S A G M; Manoe R; Muller A; Visser C A; Meijer C J L M; Musters R J P; Hack C E; Aarden L A; Niessen H W M
Clusterin: a protective mediator for ischemic cardiomyocytes?
American journal of physiology. Heart and circulatory physiology 2005;289(5):H2193-202.
2005: Zeerleder Sacha; Hack C Erik; Wuillemin Walter A
Disseminated intravascular coagulation in sepsis.
Chest 2005;128(4):2864-75.
2005: van Doorn Martijn B A; Burggraaf Jacobus; van Dam Tijtje; Eerenberg Anke; Levi Marcel; Hack Cornelis E; Schoemaker Rik C; Cohen Adam F; Nuijens Jan
A phase I study of recombinant human C1 inhibitor in asymptomatic patients with hereditary angioedema.
The Journal of allergy and clinical immunology 2005;116(4):876-83.
2005: Bade Britta; Lohrmann Jens; ten Brinke Anja; Wolbink Angela M; Wolbink Gert-Jan; ten Berge Ineke J M; Virchow J Christian; Luttmann Werner; Hack C Erik
Detection of soluble human granzyme K in vitro and in vivo.
European journal of immunology 2005;35(10):2940-8.
2005: Moons A H M; van der Zee P M; Bholasingh R; Sturk A; Hack C E; Meijers J C M; Kamp O; Cornel J H; Peters R J G; de Winter R J
The value of haemostatic markers in the triage of patients with chest pain presenting with a normal or non-diagnostic ECG.
Heart (British Cardiac Society) 2005;91(9):1215-6.
2005: van Woensel Job B M; Biezeveld Maarten H; Hack C Erik; Bos Albert P; Kuijpers Taco W
Elastase and granzymes during meningococcal disease in children: correlation to disease severity.
Intensive care medicine 2005;31(9):1239-47.
2005: Zeerleder Sacha; Hack C Erik; Caliezi Christoph; van Mierlo Gerard; Eerenberg-Belmer Anke; Wolbink Angela; Wuillenmin Walter A
Activated cytotoxic T cells and NK cells in severe sepsis and septic shock and their role in multiple organ dysfunction.
Clinical immunology (Orlando, Fla.) 2005;116(2):158-65.
2005: Mairuhu Albert T A; Peri Giuseppe; Setiati Tatty E; Hack C Erik; Koraka Penelopie; Soemantri Augustinus; Osterhaus Albert D M E; Brandjes Dees P M; van der Meer Jos W M; Mantovani Alberto; van Gorp Eric C M
Elevated plasma levels of the long pentraxin, pentraxin 3, in severe dengue virus infections.
Journal of medical virology 2005;76(4):547-52.
2005: Poland Dennis C W; García Vallejo Juan-Jesús; Niessen Hans W M; Nijmeyer Remco; Calafat Jero; Hack C Erik; Van het Hof Bert; Van Dijk Willem
Activated human PMN synthesize and release a strongly fucosylated glycoform of alpha1-acid glycoprotein, which is transiently deposited in human myocardial infarction.
Journal of leukocyte biology 2005;78(2):453-61.
2005: Familian A; Voskuyl A E; van Mierlo G J; Heijst H A; Twisk J W R; Dijkmans B A C; Hack C E
Infliximab treatment reduces complement activation in patients with rheumatoid arthritis.
Annals of the rheumatic diseases 2005;64(7):1003-8.
2005: Biezeveld M H; van Mierlo G; Lutter R; Kuipers I M; Dekker T; Hack C E; Newburger J W; Kuijpers T W
Sustained activation of neutrophils in the course of Kawasaki disease: an association with matrix metalloproteinases.
Clinical and experimental immunology 2005;141(1):183-8.
2005: Krijnen P A J; Ciurana C; Cramer T; Hazes T; Meijer C J L M; Visser C A; Niessen H W M; Hack C E
IgM colocalises with complement and C reactive protein in infarcted human myocardium.
Journal of clinical pathology 2005;58(4):382-8.
2005: Bladergroen Bellinda A; Strik Merel C M; Wolbink Angela M; Wouters Dorine; Broekhuizen Roel; Kummer J Alain; Hack C Erik
The granzyme B inhibitor proteinase inhibitor 9 (PI9) is expressed by human mast cells.
European journal of immunology 2005;35(4):1175-83.
2005: Boekholdt S Matthijs; Keller Tymen T; Wareham Nicholas J; Luben Robert; Bingham Sheila A; Day Nicholas E; Sandhu Manjinder S; Jukema J Wouter; Kastelein John J P; Hack C Erik; Khaw Kay-Tee
Serum levels of type II secretory phospholipase A2 and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk Prospective Population Study.
Arteriosclerosis, thrombosis, and vascular biology 2005;25(4):839-46.
2005: Wouters Diana; Wiessenberg Hans D; Hart Margreet; Bruins Peter; Voskuyl Alexandre; Daha Mohamed R; Hack C Erik
Complexes between C1q and C3 or C4: novel and specific markers for classical complement pathway activation.
Journal of immunological methods 2005;298(1-2):35-45.
2005: de Vroege Roel; Stooker Wim; van Oeveren Wim; Bakker Edwin W M; Huybregts Rien A J M; van Klarenbosch Jan; van Kamp Gerard J; Hack C Erik; Eijsman Leon; Wildevuur Charles R H
The impact of heparin coated circuits upon metabolism in vital organs: effect upon cerebral and renal function during and after cardiopulmonary bypass.
ASAIO journal (American Society for Artificial Internal Organs : 1992) 2005;51(1):103-9.
2005: Portielje Johanna E A; Kruit Wim H J; Eerenberg Anke J M; Schuler Martin; Sparreboom Alex; Lamers Cor H J; Gratama Jan-Willem; Stoter Gerrit; Huber Christoph; Hack C Erik
Subcutaneous injection of interleukin 12 induces systemic inflammatory responses in humans: implications for the use of IL-12 as vaccine adjuvant.
Cancer immunology, immunotherapy : CII 2005;54(1):37-43.
2005: de Bruin Eric C; Duitman Erwin H; de Boer Arjo L; Veenhuis Marten; Bos Ineke G A; Hack C Erik
Pharmaceutical proteins from methylotrophic yeasts.
Methods in molecular biology (Clifton, N.J.) 2005;308():65-76.
2004: Nijmeijer R; Krijnen P A J; Assink J; Klaarenbeek M A R; Lagrand W K; Veerhuis R; Visser C A; Meijer C J L M; Niessen H W M; Hack C E
C-reactive protein and complement depositions in human infarcted myocardium are more extensive in patients with reinfarction or upon treatment with reperfusion.
European journal of clinical investigation 2004;34(12):803-10.
2004: Kircher Brigitte; Hack C Erik; Dickinson Anne M; Wang Xiao N; Oudshoorn Machteld; Sachs Annemarie; Wolbink Angela; Niederwieser Dietger; Eibl Günther J; van Houwelingen Hans C; Goulmy Els
Towards functional transplant donor matching by measurement of granzyme A and granzyme B production levels.
Journal of immunological methods 2004;293(1-2):51-9.
2004: Padilla Niubel Diaz; Ciurana Caroline; van Oers Joep; Ogilvie Aernout C; Hack C Erik
Levels of natural IgM antibodies against phosphorylcholine in healthy individuals and in patients undergoing isolated limb perfusion.
Journal of immunological methods 2004;293(1-2):1-11.
2004: Rowshani Ajda T; Florquin Sandrine; Bemelman Frederike; Kummer J Alain; Hack C Erik; Ten Berge Ineke J M
Hyperexpression of the granzyme B inhibitor PI-9 in human renal allografts: a potential mechanism for stable renal function in patients with subclinical rejection.
Kidney international 2004;66(4):1417-22.
2004: Boekholdt S Matthijs; Peters Ron J G; Day Nicholas E; Luben Robert; Bingham Sheila A; Wareham Nicholas J; Hack C Erik; Reitsma Pieter H; Khaw Kay-Tee
Macrophage migration inhibitory factor and the risk of myocardial infarction or death due to coronary artery disease in adults without prior myocardial infarction or stroke: the EPIC-Norfolk Prospective Population study.
The American journal of medicine 2004;117(6):390-7.
2004: Ciurana Caroline L F; Zwart Bas; van Mierlo Gerard; Hack C Erik
Complement activation by necrotic cells in normal plasma environment compares to that by late apoptotic cells and involves predominantly IgM.
European journal of immunology 2004;34(9):2609-19.
2004: Mauad Thais; van Schadewijk Annemarie; Schrumpf Jasmijn; Hack C Erik; Fernezlian Sandra; Garippo Ana L; Ejzenberg Bernardo; Hiemstra Pieter S; Rabe Klaus F; Dolhnikoff Marisa;
Lymphocytic inflammation in childhood bronchiolitis obliterans.
Pediatric pulmonology 2004;38(3):233-9.
2004: Teeling Jessica L; French Ruth R; Cragg Mark S; van den Brakel Jeroen; Pluyter Marielle; Huang Haichun; Chan Claude; Parren Paul W H I; Hack C Erik; Dechant Michael; Valerius Thomas; van de Winkel Jan G J; Glennie Martin J
Characterization of new human CD20 monoclonal antibodies with potent cytolytic activity against non-Hodgkin lymphomas.
Blood 2004;104(6):1793-800.
2004: Boekholdt S Matthijs; Peters Ron J G; Hack C Erik; Day Nicholas E; Luben Robert; Bingham Sheila A; Wareham Nicholas J; Reitsma Pieter H; Khaw Kay-Tee
IL-8 plasma concentrations and the risk of future coronary artery disease in apparently healthy men and women: the EPIC-Norfolk prospective population study.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(8):1503-8.
2004: van Mirre Edwin; Teeling Jessica L; van der Meer Jos W M; Bleeker Wim K; Hack C Erik
Monomeric IgG in intravenous Ig preparations is a functional antagonist of FcgammaRII and FcgammaRIIIb.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(1):332-9.
2004: Bos Ineke G A; Lubbers Yvonne T P; Eldering Eric; Abrahams Jan Pieter; Hack C Erik
Effect of reactive site loop elongation on the inhibitory activity of C1-inhibitor.
Biochimica et biophysica acta 2004;1699(1-2):139-44.
2004: de Vroege R; van Oeveren W; van Klarenbosch J; Stooker W; Huybregts M A J M; Hack C E; van Barneveld L; Eijsman L; Wildevuur C R H
The impact of heparin-coated cardiopulmonary bypass circuits on pulmonary function and the release of inflammatory mediators.
Anesthesia and analgesia 2004;98(6):1586-94, table of contents.
2004: Baidoshvili Alexi; Niessen Hans W M; Stooker Wim; Huybregts Rien A J M; Hack C Erik; Rauwerda Jan A; Meijer Chris J L M; Eijsman Leon; van Hinsbergh Victor W M; Schalkwijk Casper G
N(omega)-(carboxymethyl)lysine depositions in human aortic heart valves: similarities with atherosclerotic blood vessels.
Atherosclerosis 2004;174(2):287-92.
2004: Strik Merel C M; Wolbink Angela; Wouters Dorine; Bladergroen Bellinda A; Verlaan Angelique R; van Houdt Inge S; Hijlkema Sanne; Hack C Erik; Kummer J Alain
Intracellular serpin SERPINB6 (PI6) is abundantly expressed by human mast cells and forms complexes with beta-tryptase monomers.
Blood 2004;103(7):2710-7.
2004: Zwart Bas; Ciurana Caroline; Rensink Irma; Manoe Rishi; Hack C Erik; Aarden Lucien A
Complement activation by apoptotic cells occurs predominantly via IgM and is limited to late apoptotic (secondary necrotic) cells.
Autoimmunity 2004;37(2):95-102.
2004: van Mirre Edwin; van Royen Annet; Hack C Erik
IVIg-mediated amelioration of murine ITP via FcgammaRIIb is not necessarily independent of SHIP-1 and SHP-1 activity.
Blood 2004;103(5):1973; author reply 1974.
2004: Renckens Rosemarijn; Weijer Sebastiaan; de Vos Alex F; Pater Jennie M; Meijers Joost C; Hack C Erik; Levi Marcel; van der Poll Tom
Inhibition of plasmin activity by tranexamic acid does not influence inflammatory pathways during human endotoxemia.
Arteriosclerosis, thrombosis, and vascular biology 2004;24(3):483-8.
2004: Kummer J Alain; Strik Merel C M; Bladergroen Bellinda A; Hack C Erik
Production, characterization, and use of serpin antibodies.
Methods (San Diego, Calif.) 2004;32(2):141-9.
2003: Biró E; Sturk-Maquelin K N; Vogel G M T; Meuleman D G; Smit M J; Hack C E; Sturk A; Nieuwland R
Human cell-derived microparticles promote thrombus formation in vivo in a tissue factor-dependent manner.
Journal of thrombosis and haemostasis : JTH 2003;1(12):2561-8.
2003: Krijnen P A J; Meischl C; Visser C A; Hack C E; Niessen H W M; Roos D
NAD(P)H oxidase in the failing human heart.
Journal of the American College of Cardiology 2003;42(12):2170-1; author reply 2171-2.
2003: Tacx A N; Groeneveld A B J; Hart M H; Aarden L A; Hack C E
Mannan binding lectin in febrile adults: no correlation with microbial infection and complement activation.
Journal of clinical pathology 2003;56(12):956-9.
2003: Nijmeijer R; Willemsen M; Meijer C J L M; Visser C A; Verheijen R H; Gottlieb R A; Hack C E; Niessen H W M
Type II secretory phospholipase A2 binds to ischemic flip-flopped cardiomyocytes and subsequently induces cell death.
American journal of physiology. Heart and circulatory physiology 2003;285(5):H2218-24.
2003: Kuijpers Taco W; Biezeveld Maarten; Achterhuis Annemiek; Kuipers Irene; Lam Jan; Hack C E; Becker Anton E; van der Wal Allard C
Longstanding obliterative panarteritis in Kawasaki disease: lack of cyclosporin A effect.
Pediatrics 2003;112(4):986-92.
2003: Zeerleder S; Zürcher Zenklusen R; Hack C E; Wuillemin W A
Disseminated intravascular coagulation in meningococcal sepsis. Case 7.
Hämostaseologie 2003;23(3):125-30.
2003: Diaz Padilla Niubel; Bleeker Wim K; Lubbers Yvonne; Rigter Gemma M M; Van Mierlo Gerard J; Daha Mohamed R; Hack C Erik
Rat C-reactive protein activates the autologous complement system.
Immunology 2003;109(4):564-71.
2003: Bos Ineke G A; Lubbers Yvonne T P; Roem Dorina; Abrahams Jan Pieter; Hack C Erik; Eldering Eric
The functional integrity of the serpin domain of C1-inhibitor depends on the unique N-terminal domain, as revealed by a pathological mutant.
The Journal of biological chemistry 2003;278(32):29463-70.
2003: Suharti Catharina; van Gorp Eric C M; Dolmans Wil M V; Setiati Tatty E; Hack C Erik; Djokomoeljanto Robert; van der Meer Jos W M
Cytokine patterns during dengue shock syndrome.
European cytokine network 2003;14(3):172-7.
2003: Zeerleder Sacha; Caliezi Christoph; van Mierlo Gerard; Eerenberg-Belmer Anke; Sulzer Irmela; Hack C Erik; Wuillemin Walter A
Administration of C1 inhibitor reduces neutrophil activation in patients with sepsis.
Clinical and diagnostic laboratory immunology 2003;10(4):529-35.
2003: Zeerleder Sacha; Zwart Bas; Wuillemin Walter A; Aarden Lucien A; Groeneveld A B Johan; Caliezi Christoph; van Nieuwenhuijze Annemarie E M; van Mierlo Gerard J; Eerenberg Anke J M; Lämmle Bernhard; Hack C Erik
Elevated nucleosome levels in systemic inflammation and sepsis.
Critical care medicine 2003;31(7):1947-51.
2003: Nijmeijer Remco; Lagrand Wim K; Lubbers Yvonne T P; Visser Cees A; Meijer Chris J L M; Niessen Hans W M; Hack C Erik
C-reactive protein activates complement in infarcted human myocardium.
The American journal of pathology 2003;163(1):269-75.
2003: de Kleijn Ester D; de Groot Ronald; Hack C Erik; Mulder Paul G H; Engl Werner; Moritz Berta; Joosten Koen F M; Hazelzet Jan A
Activation of protein C following infusion of protein C concentrate in children with severe meningococcal sepsis and purpura fulminans: a randomized, double-blinded, placebo-controlled, dose-finding study.
Critical care medicine 2003;31(6):1839-47.
2003: Hermsen C C; Konijnenberg Y; Mulder L; Loé C; van Deuren M; van der Meer J W M; van Mierlo G J; Eling W M C; Hack C E; Sauerwein R W
Circulating concentrations of soluble granzyme A and B increase during natural and experimental Plasmodium falciparum infections.
Clinical and experimental immunology 2003;132(3):467-72.
2003: Branger Judith; van den Blink Bernt; Weijer Sebastiaan; Gupta Abhya; van Deventer Sander J H; Hack C Erik; Peppelenbosch Maikel P; van der Poll Tom
Inhibition of coagulation, fibrinolysis, and endothelial cell activation by a p38 mitogen-activated protein kinase inhibitor during human endotoxemia.
Blood 2003;101(11):4446-8.
2003: Bos Ineke G A; de Bruin Eric C; Karuntu Yani A; Modderman Piet W; Eldering Eric; Hack C Erik
Recombinant human C1-inhibitor produced in Pichia pastoris has the same inhibitory capacity as plasma C1-inhibitor.
Biochimica et biophysica acta 2003;1648(1-2):75-83.
2003: Koraka Penelopie; Murgue Bernadette; Deparis Xavier; Setiati Tatty E; Suharti Catarina; van Gorp Eric C M; Hack C E; Osterhaus Albert D M E; Groen Jan
Elevated levels of total and dengue virus-specific immunoglobulin E in patients with varying disease severity.
Journal of medical virology 2003;70(1):91-8.
2003: Biezeveld Maarten H; Kuipers Irene M; Geissler Judy; Lam Jan; Ottenkamp Jaap J; Hack C Erik; Kuijpers Taco W
Association of mannose-binding lectin genotype with cardiovascular abnormalities in Kawasaki disease.
Lancet 2003;361(9365):1268-70.
2003: Krijnen P A J; Meischl C; Hack C E; Meijer C J L M; Visser C A; Roos D; Niessen H W M
Increased Nox2 expression in human cardiomyocytes after acute myocardial infarction.
Journal of clinical pathology 2003;56(3):194-9.
2003: Groeneveld A B J; Tacx A N; Bossink A W J; van Mierlo G J; Hack C E
Circulating inflammatory mediators predict shock and mortality in febrile patients with microbial infection.
Clinical immunology (Orlando, Fla.) 2003;106(2):106-15.
2003: Niessen Hans W M; Hack C Erik
C-reactive protein and the risk of cardiovascular mortality.
The American journal of medicine 2003;114(3):241-2.
2003: Verbon Annelies; Meijers Joost C M; Spek C Arnold; Hack C Erik; Pribble John P; Turner Terence; Dekkers Pascale E P; Axtelle Tim; Levi Marcel; van Deventer Sander J H; Reitsma Pieter H; van der Poll Tom
Effects of IC14, an anti-CD14 antibody, on coagulation and fibrinolysis during low-grade endotoxemia in humans.
The Journal of infectious diseases 2003;187(1):55-61.
2003: Roos Anja; Bouwman Lee H; Munoz Jeric; Zuiverloon Tahlita; Faber-Krol Maria C; Fallaux-van den Houten Francien C; Klar-Mohamad Ngaisah; Hack C Erik; Tilanus Marcel G; Daha Mohamed R
Functional characterization of the lectin pathway of complement in human serum.
Molecular immunology 2003;39(11):655-68.
2003: Hack C Erik
Derangements of coagulation and fibrinolysis in infectious diseases.
Contributions to microbiology 2003;10():18-37.
2002: Mulder C; Schoonenboom S N M; Wahlund L-O; Scheltens Ph; van Kamp G J; Veerhuis R; Hack C E; Blomberg M; Schutgens R B H; Eikelenboom P
CSF markers related to pathogenetic mechanisms in Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2002;109(12):1491-8.
2002: Niessen Hans W M; Krijnen Paul A J; Visser Cees A; Meijer Chris J L M; Hack C Erik
Intercellular adhesion molecule-1 in the heart.
Annals of the New York Academy of Sciences 2002;973():573-85.
2002: Berckmans René J; Nieuwland Rienk; Tak Paul Peter; Böing Anita N; Romijn Fred P H T M; Kraan Maarten C; Breedveld Ferdinand C; Hack C Erik; Sturk Augueste
Cell-derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII-dependent mechanism.
Arthritis and rheumatism 2002;46(11):2857-66.
2002: Diris Jart H C; Hermens Wim Th; Hemker Pieter W; Lagrand Wim K; Hack C Erik; van Dieijen-Visser Marja P
Pharmacokinetics of C1-inhibitor protein in patients with acute myocardial infarction.
Clinical pharmacology and therapeutics 2002;72(5):498-504.
2002: Strik Merel C; Bladergroen Bellinda A; Wouters Dorine; Kisiel Walter; Hooijberg Jan Hendrik; Verlaan Angelique R; Hordijk Peter L; Schneider Pascal; Hack C Erik; Kummer J Alain
Distribution of the human intracellular serpin protease inhibitor 8 in human tissues.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(11):1443-54.
2002: Krijnen P A J; Nijmeijer R; Meijer C J L M; Visser C A; Hack C E; Niessen H W M
Apoptosis in myocardial ischaemia and infarction.
Journal of clinical pathology 2002;55(11):801-11.
2002: de Zwaan C; Kleine A H; Diris J H C; Glatz J F C; Wellens H J J; Strengers P F W; Tissing M; Hack C E; van Dieijen-Visser M P; Hermens W T
Continuous 48-h C1-inhibitor treatment, following reperfusion therapy, in patients with acute myocardial infarction.
European heart journal 2002;23(21):1670-7.
2002: Hack C Erik; de Zwaan Chris; Hermens Wim T
Safety of C1-inhibitor for clinical use.
Circulation 2002;106(18):e132; author reply e132.
2002: Jellema Wilbert T; Veerman D Peter; De Winter Robbert J; Wesseling Karel H; Van Deventer Sander J H; Hack C Erik; van Lieshout Johannes J
In vivo interaction of endotoxin and recombinant bactericidal/permeability-increasing protein (rBPI23): hemodynamic effects in a human endotoxemia model.
The Journal of laboratory and clinical medicine 2002;140(4):228-35.
2002: Kuijf M L; Kwekkeboom Jaap; Kuijpers Marianne A; Willems Marc; Zondervan Pieter E; Niesters Hubert G M; Hop Wim C J; Hack C Erik; Paavonen Timo; Höckerstedt Krister; Tilanus Hugo W; Lautenschlager Irmeli; Metselaar Herold J;
Granzyme expression in fine-needle aspirates from liver allografts is increased during acute rejection.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2002;8(10):952-6.
2002: Roos Anja; Ramwadhdoebé Tamara H; Nauta Alma J; Hack C Erik; Daha Mohamed R
Therapeutic inhibition of the early phase of complement activation.
Immunobiology 2002;205(4-5):595-609.
2002: Bos Ineke G A; Hack C Erik; Abrahams Jan Pieter
Structural and functional aspects of C1-inhibitor.
Immunobiology 2002;205(4-5):518-33.
2002: Caliezi Christoph; Zeerleder Sacha; Redondo Maurice; Regli Bruno; Rothen Hans-Ulrich; Zürcher-Zenklusen Regula; Rieben Robert; Devay Jan; Hack C Erik; Lämmle Bernhard; Wuillemin Walter A
C1-inhibitor in patients with severe sepsis and septic shock: beneficial effect on renal dysfunction.
Critical care medicine 2002;30(8):1722-8.
2002: Van Gorp Eric C M; Setiati Tatty E; Mairuhu Albert T A; Suharti Catharina; Cate Ht Hugo ten; Dolmans Wil M V; Van Der Meer Jos W M; Hack C Erik; Brandjes Dees P M
Impaired fibrinolysis in the pathogenesis of dengue hemorrhagic fever.
Journal of medical virology 2002;67(4):549-54.
2002: Bos Ineke G A; Ten Berge Ineke J M; Hack C Erik
Role of complement in graft rejection after organ transplantation.
Transfusion medicine reviews 2002;16(3):251-64.
2002: Hack C Erik; Niessen Hans W M
Cardiovascular secrets of secretory phospholipase A(2).
European journal of clinical investigation 2002;32(6):381-2.
2002: ten Berge Rosita L; Meijer Chris J L M; Dukers Danny F; Kummer J Alain; Bladergroen Bellinda A; Vos Wim; Hack C Erik; Ossenkoppele Gert J; Oudejans Joost J
Expression levels of apoptosis-related proteins predict clinical outcome in anaplastic large cell lymphoma.
Blood 2002;99(12):4540-6.
2002: Branger Judith; van den Blink Bernt; Weijer Sebastiaan; Madwed Jeffrey; Bos Carina L; Gupta Abhya; Yong Chan-Loi; Polmar Stephen H; Olszyna Dariusz P; Hack C Erik; van Deventer Sander J H; Peppelenbosch Maikel P; van der Poll Tom
Anti-inflammatory effects of a p38 mitogen-activated protein kinase inhibitor during human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(8):4070-7.
2002: Labrijn Aran F; Koppelman Marco H G M; Verhagen Janneke; Brouwer Mieke C; Schuitemaker Hanneke; Hack C Erik; Huisman Han G
Novel strategy for the selection of human recombinant Fab fragments to membrane proteins from a phage-display library.
Journal of immunological methods 2002;261(1-2):37-48.
2002: Baidoshvili A; Nijmeijer R; Lagrand W K; Hack C E; Niessen H W M
Localisation of C reactive protein in infarcted tissue sites of multiple organs during sepsis.
Journal of clinical pathology 2002;55(2):152-3.
2002: Suharti Catharina; van Gorp Eric C M; Setiati Tatty E; Dolmans Wil M V; Djokomoeljanto Robert J; Hack C Erik; ten Cate Hugo; van der Meer Jos W M
The role of cytokines in activation of coagulation and fibrinolysis in dengue shock syndrome.
Thrombosis and haemostasis 2002;87(1):42-6.
2002: Bladergroen Bellinda A; Meijer Chris J L M; ten Berge Rosita L; Hack C Erik; Muris Jettie J F; Dukers Danny F; Chott Andreas; Kazama Yoshiaki; Oudejans Joost J; van Berkum Oskar; Kummer J Alain
Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system?
Blood 2002;99(1):232-7.
2002: Nijmeijer Remco; Lagrand Wim K; Baidoshvili Alexi; Lubbers Yvonne T P; Hermens Wim Th; Meijer Chris J L M; Visser Cees A; Hack C Erik; Niessen Hans W M
Secretory type II phospholipase A(2) binds to ischemic myocardium during myocardial infarction in humans.
Cardiovascular research 2002;53(1):138-46.
2001: van der Kolk L E; Grillo-López A J; Baars J W; Hack C E; van Oers M H
Complement activation plays a key role in the side-effects of rituximab treatment.
British journal of haematology 2001;115(4):807-11.
2001: Hack C E
Fibrinolysis in disseminated intravascular coagulation.
Seminars in thrombosis and hemostasis 2001;27(6):633-8.
2001: Koraka P; Suharti C; Setiati T E; Mairuhu A T; Van Gorp E; Hack C E; Juffrie M; Sutaryo J; Van Der Meer G M; Groen J; Osterhaus A D
Kinetics of dengue virus-specific serum immunoglobulin classes and subclasses correlate with clinical outcome of infection.
Journal of clinical microbiology 2001;39(12):4332-8.
2001: Bleeker W K; Teeling J L; Hack C E
Accelerated autoantibody clearance by intravenous immunoglobulin therapy: studies in experimental models to determine the magnitude and time course of the effect.
Blood 2001;98(10):3136-42.
2001: Groeneveld A B; Bossink A W; van Mierlo G J; Hack C E
Circulating inflammatory mediators in patients with fever: predicting bloodstream infection.
Clinical and diagnostic laboratory immunology 2001;8(6):1189-95.
2001: Lagrand W K; Niessen H W; Nijmeijer R; Hack C E
Role for complement as an intermediate between C-reactive protein and intercellular adhesion molecule-1 expression?
Circulation 2001;104(9):E46.
2001: Bos I G; van Mierlo G J; Bleeker W K; Rigter G M; te Velthuis H; Dickneite G; Hack C E
The potentiation of human C1-inhibitor by dextran sulphate is transient in vivo: studies in a rat model.
International immunopharmacology 2001;1(8):1583-95.
2001: Teeling J L; Jansen-Hendriks T; Kuijpers T W; de Haas M; van de Winkel J G; Hack C E; Bleeker W K
Therapeutic efficacy of intravenous immunoglobulin preparations depends on the immunoglobulin G dimers: studies in experimental immune thrombocytopenia.
Blood 2001;98(4):1095-9.
2001: Zeerleder S; Hack C E; Caliezi C; Hebeisen R; Wuillemin W A
Bacillus Calmette-Guérin sepsis: shift of an intended local toward a detrimental systemic cytotoxic immune response.
Blood 2001;98(3):890-1.
2001: Juffrie M; Meer G M; Hack C E; Haasnoot K; Sutaryo; Veerman A J; Thijs L G
Inflammatory mediators in dengue virus infection in children: interleukin-6 and its relation to C-reactive protein and secretory phospholipase A2.
The American journal of tropical medicine and hygiene 2001;65(1):70-5.
2001: Hack C E; Zeerleder S
The endothelium in sepsis: source of and a target for inflammation.
Critical care medicine 2001;29(7 Suppl):S21-7.
2001: Familian A; Zwart B; Huisman H G; Rensink I; Roem D; Hordijk P L; Aarden L A; Hack C E
Chromatin-independent binding of serum amyloid P component to apoptotic cells.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(2):647-54.
2001: de Jonge E; Dekkers P E; Creasey A A; Hack C E; Paulson S K; Karim A; Kesecioglu J; Levi M; van Deventer S J; van der Poll T
Tissue factor pathway inhibitor does not influence inflammatory pathways during human endotoxemia.
The Journal of infectious diseases 2001;183(12):1815-8.
2001: Joop K; Berckmans R J; Nieuwland R; Berkhout J; Romijn F P; Hack C E; Sturk A
Microparticles from patients with multiple organ dysfunction syndrome and sepsis support coagulation through multiple mechanisms.
Thrombosis and haemostasis 2001;85(5):810-20.
2001: Molenaar E T; Voskuyl A E; Familian A; van Mierlo G J; Dijkmans B A; Hack C E
Complement activation in patients with rheumatoid arthritis mediated in part by C-reactive protein.
Arthritis and rheumatism 2001;44(5):997-1002.
2001: Juffermans N P; Verbon A; Schultz M J; Hack C E; van Deventer S J; Speelman P; van der Poll T
Thalidomide inhibits granulocyte responses in healthy humans after ex vivo stimulation with bacterial antigens.
Antimicrobial agents and chemotherapy 2001;45(5):1547-9.
2001: Berckmans R J; Neiuwland R; Böing A N; Romijn F P; Hack C E; Sturk A
Cell-derived microparticles circulate in healthy humans and support low grade thrombin generation.
Thrombosis and haemostasis 2001;85(4):639-46.
2001: van Gorp E C; Minnema M C; Suharti C; Mairuhu A T; Brandjes D P; ten Cate H; Hack C E; Meijers J C
Activation of coagulation factor XI, without detectable contact activation in dengue haemorrhagic fever.
British journal of haematology 2001;113(1):94-9.
2001: Meijer C; Wiezer M J; Hack C E; Boelens P G; Wedel N I; Meijer S; Nijveldt R J; Statius Muller M G; Wiggers T; Zoetmulder F A; Borel Rinkes I H; Cuesta M A; Gouma D J; van de Velde C J; Tilanus H W; Scotté M; Thijs L G; van Leeuwen P A
Coagulopathy following major liver resection: the effect of rBPI21 and the role of decreased synthesis of regulating proteins by the liver.
Shock (Augusta, Ga.) 2001;15(4):261-71.
2001: Nijmeijer R; Lagrand W K; Visser C A; Meijer C J; Niessen H W; Hack C E
CRP, a major culprit in complement-mediated tissue damage in acute myocardial infarction?
International immunopharmacology 2001;1(3):403-14.
2001: Teeling J L; Bleeker W K; Rigter G M; van Rooijen N; Kuijpers T W; Hack C E
Intravenous immunoglobulin preparations induce mild activation of neutrophils in vivo via triggering of macrophages--studies in a rat model.
British journal of haematology 2001;112(4):1031-40.
2001: Verbon A; Dekkers P E; ten Hove T; Hack C E; Pribble J P; Turner T; Souza S; Axtelle T; Hoek F J; van Deventer S J; van der Poll T
IC14, an anti-CD14 antibody, inhibits endotoxin-mediated symptoms and inflammatory responses in humans.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3599-605.
2001: Bladergroen B A; Strik M C; Bovenschen N; van Berkum O; Scheffer G L; Meijer C J; Hack C E; Kummer J A
The granzyme B inhibitor, protease inhibitor 9, is mainly expressed by dendritic cells and at immune-privileged sites.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(5):3218-25.
2001: Portielje J E; Kruit W H; Eerenberg A J; Schuler M; Sparreboom A; Lamers C H; Bolhuis R L; Stoter G; Huber C; Hack C
Interleukin 12 induces activation of fibrinolysis and coagulation in humans.
British journal of haematology 2001;112(2):499-505.
2000: Citarella F; te Velthuis H; Helmer-Citterich M; Hack C E
Identification of a putative binding site for negatively charged surfaces in the fibronectin type II domain of human factor XII--an immunochemical and homology modeling approach.
Thrombosis and haemostasis 2000;84(6):1057-65.
2000: Niessen H W; Lagrand W K; Rensink H J; Meijer C J; Aarden L; Hack C E; Visser C
Apolipoprotein H, a new mediator in the inflammatory changes ensuring in jeopardised human myocardium.
Journal of clinical pathology 2000;53(11):863-7.
2000: Minnema M C; Peters R J; de Winter R; Lubbers Y P; Barzegar S; Bauer K A; Rosenberg R D; Hack C E; ten Cate H
Activation of clotting factors XI and IX in patients with acute myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(11):2489-93.
2000: Lagrand W K; Visser C A; Hack C E; Niessen H W; Nijmeijer R
C-reactive protein and cardiovascular disease: linked by complement?
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2000;15(10):1709-10.
2000: Hack C E
Tissue factor pathway of coagulation in sepsis.
Critical care medicine 2000;28(9 Suppl):S25-30.
2000: Lauw F N; Pajkrt D; Hack C E; Kurimoto M; van Deventer S J; van der Poll T
Proinflammatory effects of IL-10 during human endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(5):2783-9.
2000: Bruins P; te Velthuis H; Eerenberg-Belmer A J; Yazdanbakhsh A P; de Beaumont E M; Eijsman L; Trouwborst A; Hack C E
Heparin-protamine complexes and C-reactive protein induce activation of the classical complement pathway: studies in patients undergoing cardiac surgery and in vitro.
Thrombosis and haemostasis 2000;84(2):237-43.
2000: Schultz M J; Speelman P; Hack C E; Buurman W A; van Deventer S J; van Der Poll T
Intravenous infusion of erythromycin inhibits CXC chemokine production, but augments neutrophil degranulation in whole blood stimulated with Streptococcus pneumoniae.
The Journal of antimicrobial chemotherapy 2000;46(2):235-40.
2000: Lauw F N; Simpson A J; Hack C E; Prins J M; Wolbink A M; van Deventer S J; Chaowagul W; White N J; van Der Poll T
Soluble granzymes are released during human endotoxemia and in patients with severe infection due to gram-negative bacteria.
The Journal of infectious diseases 2000;182(1):206-13.
2000: Straatsburg I H; Boermeester M A; Wolbink G J; van Gulik T M; Gouma D J; Frederiks W M; Hack C E
Complement activation induced by ischemia-reperfusion in humans: a study in patients undergoing partial hepatectomy.
Journal of hepatology 2000;32(5):783-91.
2000: Caliezi C; Wuillemin W A; Zeerleder S; Redondo M; Eisele B; Hack C E
C1-Esterase inhibitor: an anti-inflammatory agent and its potential use in the treatment of diseases other than hereditary angioedema.
Pharmacological reviews 2000;52(1):91-112.
2000: Bleeker W K; Teeling J L; Verhoeven A J; Rigter G M; Agterberg J; Tool A T; Koenderman A H; Kuijpers T W; Hack C E
Vasoactive side effects of intravenous immunoglobulin preparations in a rat model and their treatment with recombinant platelet-activating factor acetylhydrolase.
Blood 2000;95(5):1856-61.
2000: Spaeny-Dekking E H; Kamp A M; Froelich C J; Hack C E
Extracellular granzyme A, complexed to proteoglycans, is protected against inactivation by protease inhibitors.
Blood 2000;95(4):1465-72.
2000: de Jonge E; Dekkers P E; Creasey A A; Hack C E; Paulson S K; Karim A; Kesecioglu J; Levi M; van Deventer S J; van Der Poll T
Tissue factor pathway inhibitor dose-dependently inhibits coagulation activation without influencing the fibrinolytic and cytokine response during human endotoxemia.
Blood 2000;95(4):1124-9.
2000: Minnema M C; Chang A C; Jansen P M; Lubbers Y T; Pratt B M; Whittaker B G; Taylor F B; Hack C E; Friedman B
Recombinant human antithrombin III improves survival and attenuates inflammatory responses in baboons lethally challenged with Escherichia coli.
Blood 2000;95(4):1117-23.
2000: Nieuwland R; Berckmans R J; McGregor S; Böing A N; Romijn F P; Westendorp R G; Hack C E; Sturk A
Cellular origin and procoagulant properties of microparticles in meningococcal sepsis.
Blood 2000;95(3):930-5.
2000: Juffrie M; van Der Meer G M; Hack C E; Haasnoot K; Sutaryo; Veerman A J; Thijs L G
Inflammatory mediators in dengue virus infection in children: interleukin-8 and its relationship to neutrophil degranulation.
Infection and immunity 2000;68(2):702-7.
2000: Hack C E
C1-inhibitor: antigenic and functional analysis.
Methods in molecular biology (Clifton, N.J.) 2000;150():159-72.
1999: Veerhuis R; Janssen I; De Groot C J; Van Muiswinkel F L; Hack C E; Eikelenboom P
Cytokines associated with amyloid plaques in Alzheimer's disease brain stimulate human glial and neuronal cell cultures to secrete early complement proteins, but not C1-inhibitor.
Experimental neurology 1999;160(1):289-99.
1999: Minnema M C; Wittekoek M E; Schoonenboom N; Kastelein J J; Hack C E; ten Cate H
Activation of the contact system of coagulation does not contribute to the hemostatic imbalance in hypertriglyceridemia.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(10):2548-53.
1999: Bossink A W; Groeneveld A B; Hack C E; Thijs L G
The clinical host response to microbial infection in medical patients with fever.
Chest 1999;116(2):380-90.
1999: Lauw F N; te Velde A A; Dekkers P E; Speelman P; Aerts J M; Hack C E; van Deventer S J; van der Poll T
Activation of mononuclear cells by interleukin-12: an in vivo study in chimpanzees.
Journal of clinical immunology 1999;19(4):231-8.
1999: Lagrand W K; Visser C A; Hermens W T; Niessen H W; Verheugt F W; Wolbink G J; Hack C E
C-reactive protein as a cardiovascular risk factor: more than an epiphenomenon?
Circulation 1999;100(1):96-102.
1999: Wiezer M J; Meijer C; Vuylsteke R; Pullens R H; Prins H A; Cuesta M A; Meijer S; Hack C E; van Leeuwen P A
Is major liver surgery associated with an increased systemic inflammatory response? A prospective comparison of hemihepatectomy and other major abdominal surgery.
Liver 1999;19(3):220-7.
1999: Tak P P; Spaeny-Dekking L; Kraan M C; Breedveld F C; Froelich C J; Hack C E
The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA).
Clinical and experimental immunology 1999;116(2):366-70.
1999: Robers M; Rensink I J; Hack C E; Aarden L A; Reutelingsperger C P; Glatz J F; Hermens W T
A new principle for rapid immunoassay of proteins based on in situ precipitate-enhanced ellipsometry.
Biophysical journal 1999;76(5):2769-76.
1999: Wiezer M J; Meijer C; Wallast-Groenewoud H P; Tool A T; Prins H A; Houdijk A P; Beelen R H; Meijer S; Hack C E; van Leeuwen P A
Impaired leukocyte phagocytosis in patients undergoing hemihepatectomy for liver metastases.
Liver transplantation and surgery : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 1999;5(3):238-45.
1999: Niessen H W; Lagrand W K; Visser C A; Meijer C J; Hack C E
Upregulation of ICAM-1 on cardiomyocytes in jeopardized human myocardium during infarction.
Cardiovascular research 1999;41(3):603-10.
1999: Wever P C; Spaeny L H; van der Vliet H J; Rentenaar R J; Wolbink A M; Surachno J; Wertheim P M; Schellekens P T; Hack C E; ten Berge I J
Expression of granzyme B during primary cytomegalovirus infection after renal transplantation.
The Journal of infectious diseases 1999;179(3):693-6.
1999: Lauw F N; Dekkers P E; te Velde A A; Speelman P; Levi M; Kurimoto M; Hack C E; van Deventer S J; van der Poll T
Interleukin-12 induces sustained activation of multiple host inflammatory mediator systems in chimpanzees.
The Journal of infectious diseases 1999;179(3):646-52.
1999: Minnema M C; Ten Cate H; Hack C E
The role of factor XI in coagulation: a matter of revision.
Seminars in thrombosis and hemostasis 1999;25(4):419-28.
1998: ten Berge I J; Wever P C; Rentenaar R J; Spaeny L H; Surachno J; Wertheim P M; Schellekens P T; Hack C E
Selective expansion of a peripheral blood CD8+ memory T cell subset expressing both granzyme B and L-selectin during primary viral infection in renal allograft recipients.
Transplantation proceedings 1998;30(8):3975-7.
1998: ten Berge I J; Wever P C; Wolbink A M; Surachno J; Wertheim P M; Spaeny L H; Hack C E
Increased systemic levels of soluble granzymes A and B during primary cytomegalovirus infection after renal transplantation.
Transplantation proceedings 1998;30(8):3972-4.
1998: Citarella F; Fedele G; Roem D; Fantoni A; Hack C E
The second exon-encoded factor XII region is involved in the interaction of factor XII with factor XI and does not contribute to the binding site for negatively charged surfaces.
Blood 1998;92(11):4198-206.
1998: Teeling J L; De Groot E R; Eerenberg A J; Bleeker W K; Van Mierlo G; Aarden L A; Hack C E
Human intravenous immunoglobulin (IVIG) preparations degranulate human neutrophils in vitro.
Clinical and experimental immunology 1998;114(2):264-70.
1998: Minnema M C; Pajkrt D; Wuillemin W A; Roem D; Bleeker W K; Levi M; van Deventer S J; Hack C E; ten Cate H
Activation of clotting factor XI without detectable contact activation in experimental human endotoxemia.
Blood 1998;92(9):3294-301.
1998: Hazelzet J A; de Groot R; van Mierlo G; Joosten K F; van der Voort E; Eerenberg A; Suur M H; Hop W C; Hack C E
Complement activation in relation to capillary leakage in children with septic shock and purpura.
Infection and immunity 1998;66(11):5350-6.
1998: van Dullemen H M; Wolbink G J; Wever P C; van der Poll T; Hack C E; Tytgat G N; van Deventer S J
Reduction of circulating secretory phospholipase A2 levels by anti-tumor necrosis factor chimeric monoclonal antibody in patients with severe Crohn's disease. Relation between tumor necrosis factor and secretory phospholipase A2 in healthy humans and in active Crohn's disease.
Scandinavian journal of gastroenterology 1998;33(10):1094-8.
1998: Veerhuis R; Janssen I; Hoozemans J J; De Groot C J; Hack C E; Eikelenboom P
Complement C1-inhibitor expression in Alzheimer's disease.
Acta neuropathologica 1998;96(3):287-96.
1998: Wever P C; Boonstra J G; Laterveer J C; Hack C E; van der Woude F J; Daha M R; ten Berge I J
Mechanisms of lymphocyte-mediated cytotoxicity in acute renal allograft rejection.
Transplantation 1998;66(2):259-64.
1998: Bossink A W; Groeneveld J; Hack C E; Thijs L G
Prediction of mortality in febrile medical patients: How useful are systemic inflammatory response syndrome and sepsis criteria?
Chest 1998;113(6):1533-41.
1998: Bruins P; te Velthuis H; Jansen P G; Eijsman L; Hack C E
Biphasic release of secretory phospholipase A2 during and after cardiopulmonary bypass.
The Journal of thoracic and cardiovascular surgery 1998;115(4):949-51.
1998: Blom M; Tool A T; Wever P C; Wolbink G J; Brouwer M C; Calafat J; Egesten A; Knol E F; Hack C E; Roos D; Verhoeven A J
Human eosinophils express, relative to other circulating leukocytes, large amounts of secretory 14-kD phospholipase A2.
Blood 1998;91(8):3037-43.
1998: Spaeny-Dekking E H; Hanna W L; Wolbink A M; Wever P C; Kummer J A; Swaak A J; Middeldorp J M; Huisman H G; Froelich C J; Hack C E
Extracellular granzymes A and B in humans: detection of native species during CTL responses in vitro and in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(7):3610-6.
1998: Wever P C; Van Der Vliet H J; Spaeny L H; Wolbink A M; Van Diepen F N; Froelich C J; Hack C E; ten Berge I J
The CD8+ granzyme B+ T-cell subset in peripheral blood from healthy individuals contains activated and apoptosis-prone cells.
Immunology 1998;93(3):383-9.
1998: Jansen P M; Eisele B; de Jong I W; Chang A; Delvos U; Taylor F B; Hack C E
Effect of C1 inhibitor on inflammatory and physiologic response patterns in primates suffering from lethal septic shock.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):475-84.
1998: Wever P C; Aten J; Rentenaar R J; Hack C E; Koopman G; Weening J J; ten Berge I J
Apoptotic tubular cell death during acute renal allograft rejection.
Clinical nephrology 1998;49(1):28-34.
1998: Minnema M C; Friederich P W; Levi M; von dem Borne P A; Mosnier L O; Meijers J C; Biemond B J; Hack C E; Bouma B N; ten Cate H
Enhancement of rabbit jugular vein thrombolysis by neutralization of factor XI. In vivo evidence for a role of factor XI as an anti-fibrinolytic factor.
The Journal of clinical investigation 1998;101(1):10-4.
1998: Wolbink G J; Bossink A W; Groeneveld A B; de Groot M C; Thijs L G; Hack C E
Complement activation in patients with sepsis is in part mediated by C-reactive protein.
The Journal of infectious diseases 1998;177(1):81-7.
1998: Vervloet M G; Thijs L G; Hack C E
Derangements of coagulation and fibrinolysis in critically ill patients with sepsis and septic shock.
Seminars in thrombosis and hemostasis 1998;24(1):33-44.
1997: Groeneveld A B; Kindt I; Raijmakers P G; Hack C E; Thijs L G
Systemic coagulation and fibrinolysis in patients with or at risk for the adult respiratory distress syndrome.
Thrombosis and haemostasis 1997;78(6):1444-9.
1997: Buysmann S; Hack C E; van Diepen F N; Surachno J; ten Berge I J
Administration of OKT3 as a two-hour infusion attenuates first-dose side effects.
Transplantation 1997;64(11):1620-3.
1997: Groeneveld A B; Raijmakers P G; Rauwerda J A; Hack C E
The inflammatory response to vascular surgery-associated ischaemia and reperfusion in man: effect on postoperative pulmonary function.
European journal of vascular and endovascular surgery : the official journal of the European Society for Vascular Surgery 1997;14(5):351-9.
1997: Bruins P; te Velthuis H; Yazdanbakhsh A P; Jansen P G; van Hardevelt F W; de Beaumont E M; Wildevuur C R; Eijsman L; Trouwborst A; Hack C E
Activation of the complement system during and after cardiopulmonary bypass surgery: postsurgery activation involves C-reactive protein and is associated with postoperative arrhythmia.
Circulation 1997;96(10):3542-8.
1997: Nieuwland R; Berckmans R J; Rotteveel-Eijkman R C; Maquelin K N; Roozendaal K J; Jansen P G; ten Have K; Eijsman L; Hack C E; Sturk A
Cell-derived microparticles generated in patients during cardiopulmonary bypass are highly procoagulant.
Circulation 1997;96(10):3534-41.
1997: Citarella F; Wuillemin W A; Lubbers Y T; Hack C E
Initiation of contact system activation in plasma is dependent on factor XII autoactivation and not on enhanced susceptibility of factor XII for kallikrein cleavage.
British journal of haematology 1997;99(1):197-205.
1997: Hazelzet J A; Kornelisse R F; van der Pouw Kraan T C; Joosten K F; van der Voort E; van Mierlo G; Suur M H; Hop W C; de Groot R; Hack C E
Interleukin 12 levels during the initial phase of septic shock with purpura in children: relation to severity of disease.
Cytokine 1997;9(9):711-6.
1997: Niessen R W; Lamping R J; Jansen P M; Prins M H; Peters M; Taylor F B; de Vijlder J J; ten Cate J W; Hack C E; Sturk A
Antithrombin acts as a negative acute phase protein as established with studies on HepG2 cells and in baboons.
Thrombosis and haemostasis 1997;78(3):1088-92.
1997: Citarella F; Felici A; Brouwer M; Wagstaff J; Fantoni A; Hack C E
Interleukin-6 downregulates factor XII production by human hepatoma cell line (HepG2).
Blood 1997;90(4):1501-7.
1997: Wuillemin W A; te Velthuis H; Lubbers Y T; de Ruig C P; Eldering E; Hack C E
Potentiation of C1 inhibitor by glycosaminoglycans: dextran sulfate species are effective inhibitors of in vitro complement activation in plasma.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1953-60.
1997: te Velthuis H; Baufreton C; Jansen P G; Thijs C M; Hack C E; Sturk A; Wildevuur C R; Loisance D Y
Heparin coating of extracorporeal circuits inhibits contact activation during cardiac operations.
The Journal of thoracic and cardiovascular surgery 1997;114(1):117-22.
1997: van der Poll T; Jansen P M; Van Zee K J; Hack C E; Oldenburg H A; Loetscher H; Lesslauer W; Lowry S F; Moldawer L L
Pretreatment with a 55-kDa tumor necrosis factor receptor-immunoglobulin fusion protein attenuates activation of coagulation, but not of fibrinolysis, during lethal bacteremia in baboons.
The Journal of infectious diseases 1997;176(1):296-9.
1997: Minnema M C; ten Cate H; van Beek E J; van den Ende A; Hack C E; Brandjes D P
Effects of heparin therapy on fibrinolysis in patients with pulmonary embolism.
Thrombosis and haemostasis 1997;77(6):1164-7.
1997: van der Poll T; Coyle S M; Levi M; Jansen P M; Dentener M; Barbosa K; Buurman W A; Hack C E; ten Cate J W; Agosti J M; Lowry S F
Effect of a recombinant dimeric tumor necrosis factor receptor on inflammatory responses to intravenous endotoxin in normal humans.
Blood 1997;89(10):3727-34.
1997: van der Poll T; Levi M; Dentener M; Jansen P M; Coyle S M; Braxton C C; Buurman W A; Hack C E; ten Cate J W; Lowry S F
Epinephrine exerts anticoagulant effects during human endotoxemia.
The Journal of experimental medicine 1997;185(6):1143-8.
1997: Hack C E; Wolbink G J; Schalkwijk C; Speijer H; Hermens W T; van den Bosch H
A role for secretory phospholipase A2 and C-reactive protein in the removal of injured cells.
Immunology today 1997;18(3):111-5.
1997: Kornelisse R F; Hack C E; Savelkoul H F; van der Pouw Kraan T C; Hop W C; van Mierlo G; Suur M H; Neijens H J; de Groot R
Intrathecal production of interleukin-12 and gamma interferon in patients with bacterial meningitis.
Infection and immunity 1997;65(3):877-81.
1997: Speijer H; Jans S W; Reutelingsperger C P; Hack C E; van der Vusse G J; Hermens W T
Partial coverage of phospholipid model membranes with annexin V may completely inhibit their degradation by phospholipase A2.
FEBS letters 1997;402(2-3):193-7.
1997: Corssmit E P; Heijligenberg R; Hack C E; Endert E; Sauerwein H P; Romijn J A
Effects of interferon-alpha (IFN-alpha) administration on leucocytes in healthy humans.
Clinical and experimental immunology 1997;107(2):359-63.
1997: van der Poll T; Jansen P M; Montegut W J; Braxton C C; Calvano S E; Stackpole S A; Smith S R; Swanson S W; Hack C E; Lowry S F; Moldawer L L
Effects of IL-10 on systemic inflammatory responses during sublethal primate endotoxemia.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1971-5.
1997: Lagrand W K; Niessen H W; Wolbink G J; Jaspars L H; Visser C A; Verheugt F W; Meijer C J; Hack C E
C-reactive protein colocalizes with complement in human hearts during acute myocardial infarction.
Circulation 1997;95(1):97-103.
1997: Hack C E; Aarden L A; Thijs L G
Role of cytokines in sepsis.
Advances in immunology 1997;66():101-95.
1996: Houdijk A P; Boermeester M A; Wesdorp R I; Hack C E; Van Leeuwen P A
Tumor necrosis factor unresponsiveness after surgery in bile duct-ligated rats.
The American journal of physiology 1996;271(6 Pt 1):G980-6.
1996: Hazelzet J A; Risseeuw-Appel I M; Kornelisse R F; Hop W C; Dekker I; Joosten K F; de Groot R; Hack C E
Age-related differences in outcome and severity of DIC in children with septic shock and purpura.
Thrombosis and haemostasis 1996;76(6):932-8.
1996: ten Berge R J; Buysmann S; van Diepen F N; Surachno S; Hack C E
Consequences of OKT3 administration via continuous infusion as compared to bolus infusion.
Transplantation proceedings 1996;28(6):3217-20.
1996: Stouthard J M; Levi M; Hack C E; Veenhof C H; Romijn H A; Sauerwein H P; van der Poll T
Interleukin-6 stimulates coagulation, not fibrinolysis, in humans.
Thrombosis and haemostasis 1996;76(5):738-42.
1996: Jansen P M; van der Pouw Kraan T C; de Jong I W; van Mierlo G; Wijdenes J; Aarden L; Chang A A; Taylor F B; Hack C E
The release of interleukin-12 in Escherichia coli-induced lethal and sublethal primate sepsis.
Annals of the New York Academy of Sciences 1996;795():351-3.
1996: Wever P C; Roest R W; Wolbink-Kamp A M; Wolbink G J; Weening J J; Hack C E; ten Berge J M
OKT3-induced nephrotoxicity is associated with release of group II secretory phospholipase A2.
European journal of clinical investigation 1996;26(10):873-8.
1996: Wuillemin W A; Hack C E; Bleeker W K; Biemond B J; Levi M; ten Cate H
Inactivation of factor Xia in vivo: studies in chimpanzees and in humans.
Thrombosis and haemostasis 1996;76(4):549-55.
1996: van der Poll T; Jansen P M; Van Zee K J; Welborn M B; de Jong I; Hack C E; Loetscher H; Lesslauer W; Lowry S F; Moldawer L L
Tumor necrosis factor-alpha induces activation of coagulation and fibrinolysis in baboons through an exclusive effect on the p55 receptor.
Blood 1996;88(3):922-7.
1996: Wolbink G J; Brouwer M C; Buysmann S; ten Berge I J; Hack C E
CRP-mediated activation of complement in vivo: assessment by measuring circulating complement-C-reactive protein complexes.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(1):473-9.
1996: Snijders F; Wever P C; Danner S A; Hack C E; ten Kate F J; ten Berge I J
Increased numbers of granzyme-B-expressing cytotoxic T-lymphocytes in the small intestine of HIV-infected patients.
Journal of acquired immune deficiency syndromes and human retrovirology : official publication of the International Retrovirology Association 1996;12(3):276-81.
1996: Wuillemin W A; Bleeker W K; Agterberg J; Rigter G; ten Cate H; Hack C E
Clearance of human factor XIa-inhibitor complexes in rats.
British journal of haematology 1996;93(4):950-4.
1996: Jansen P M; de Jong I W; Hart M; Kim K J; Aarden L A; Hinshaw L B; Taylor F B; Hack C E
Release of leukemia inhibitory factor in primate sepsis. Analysis of the role of TNF-alpha.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(11):4401-7.
1996: Jansen P M; van der Pouw Kraan T C; de Jong I W; van Mierlo G; Wijdenes J; Chang A A; Aarden L A; Taylor F B; Hack C E
Release of interleukin-12 in experimental Escherichia coli septic shock in baboons: relation to plasma levels of interleukin-10 and interferon-gamma.
Blood 1996;87(12):5144-51.
1996: Speijer H; Giesen P L; Zwaal R F; Hack C E; Hermens W T
Critical micelle concentrations and stirring are rate limiting in the loss of lipid mass during membrane degradation by phospholipase A2.
Biophysical journal 1996;70(5):2239-47.
1996: Citarella F; Ravon D M; Pascucci B; Felici A; Fantoni A; Hack C E
Structure/function analysis of human factor XII using recombinant deletion mutants. Evidence for an additional region involved in the binding to negatively charged surfaces.
European journal of biochemistry / FEBS 1996;238(1):240-9.
1996: Wuillemin W A; Eldering E; Citarella F; de Ruig C P; ten Cate H; Hack C E
Modulation of contact system proteases by glycosaminoglycans. Selective enhancement of the inhibition of factor XIa.
The Journal of biological chemistry 1996;271(22):12913-8.
1996: Kummer J A; Kamp A M; Citarella F; Horrevoets A J; Hack C E
Expression of human recombinant granzyme A zymogen and its activation by the cysteine proteinase cathepsin C.
The Journal of biological chemistry 1996;271(16):9281-6.
1996: te Velthuis H; Jansen P G; Hack C E; Eijsman L; Wildevuur C R
Specific complement inhibition with heparin-coated extracorporeal circuits.
The Annals of thoracic surgery 1996;61(4):1153-7.
1996: ten Cate H; Biemond B J; Levi M; Wuillemin W A; Bauer K A; Barzegar S; Buller H R; Hack C E; ten Cate J W; Rosenberg R D
Factor XIa induced activation of the intrinsic cascade in vivo.
Thrombosis and haemostasis 1996;75(3):445-9.
1996: Jansen P M; Pixley R A; Brouwer M; de Jong I W; Chang A C; Hack C E; Taylor F B; Colman R W
Inhibition of factor XII in septic baboons attenuates the activation of complement and fibrinolytic systems and reduces the release of interleukin-6 and neutrophil elastase.
Blood 1996;87(6):2337-44.
1996: Wuillemin W A; Mertens K; ten Cate H; Hack C E
Thrombin-mediated activation of endogenous factor XI in plasma in the presence of physiological glycosaminoglycans occurs only with high concentrations of thrombin.
British journal of haematology 1996;92(2):466-72.
1996: Nocker R E; Schoonbrood D F; van de Graaf E A; Hack C E; Lutter R; Jansen H M; Out T A
Interleukin-8 in airway inflammation in patients with asthma and chronic obstructive pulmonary disease.
International archives of allergy and immunology 1996;109(2):183-91.
1996: Corssmit E P; Levi M; Hack C E; ten Cate J W; Sauerwein H P; Romijn J A
Fibrinolytic response to interferon-alpha in healthy human subjects.
Thrombosis and haemostasis 1996;75(1):113-7.
1996: van der Poll T; Coyle S M; Levi M; Boermeester M A; Braxton C C; Jansen P M; Hack C E; Lowry S F
Fat emulsion infusion potentiates coagulation activation during human endotoxemia.
Thrombosis and haemostasis 1996;75(1):83-6.
1996: van der Poll T; Jansen J; Levi M; ten Cate H; Hack C E; Aarden L A; ten Cate J W; van Deventer S J
Interleukin 10 release during endotoxaemia in chimpanzees: role of platelet-activating factor and interleukin 6.
Scandinavian journal of immunology 1996;43(1):122-5.
1996: Thijs L G; Groeneveld A B; Hack C E
Multiple organ failure in septic shock.
Current topics in microbiology and immunology 1996;216():209-37.
1996: Veerhuis R; Janssen I; Hack C E; Eikelenboom P
Early complement components in Alzheimer's disease brains.
Acta neuropathologica 1996;91(1):53-60.
1995: Wuillemin W A; Fijnvandraat K; Derkx B H; Peters M; Vreede W; ten Cate H; Hack C E
Activation of the intrinsic pathway of coagulation in children with meningococcal septic shock.
Thrombosis and haemostasis 1995;74(6):1436-41.
1995: Ravon D M; Citarella F; Lubbers Y T; Pascucci B; Hack C E
Monoclonal antibody F1 binds to the kringle domain of factor XII and induces enhanced susceptibility for cleavage by kallikrein.
Blood 1995;86(11):4134-43.
1995: Thijs L G; Hack C E
Time course of cytokine levels in sepsis.
Intensive care medicine 1995;21 Suppl 2():S258-63.
1995: Wolbink G J; Schalkwijk C; Baars J W; Wagstaff J; van den Bosch H; Hack C E
Therapy with interleukin-2 induces the systemic release of phospholipase-A2.
Cancer immunology, immunotherapy : CII 1995;41(5):287-92.
1995: Bossink A W; Paemen L; Jansen P M; Hack C E; Thijs L G; Van Damme J
Plasma levels of the chemokines monocyte chemotactic proteins-1 and -2 are elevated in human sepsis.
Blood 1995;86(10):3841-7.
1995: Boermeester M A; Houdijk A P; Meyer S; Cuesta M A; Appelmelk B J; Wesdorp R I; Hack C E; Van Leeuwen P A
Liver failure induces a systemic inflammatory response. Prevention by recombinant N-terminal bactericidal/permeability-increasing protein.
The American journal of pathology 1995;147(5):1428-40.
1995: Groeneveld A B; Raijmakers P G; Hack C E; Thijs L G
Interleukin 8-related neutrophil elastase and the severity of the adult respiratory distress syndrome.
Cytokine 1995;7(7):746-52.
1995: van der Poll T; Braxton C C; Coyle S M; Boermeester M A; Wang J C; Jansen P M; Montegut W J; Calvano S E; Hack C E; Lowry S F
Effect of hypertriglyceridemia on endotoxin responsiveness in humans.
Infection and immunity 1995;63(9):3396-400.
1995: Niessen R W; Pfaffendorf B A; Sturk A; Lamping R J; Schaap M C; Hack C E; Peters M
The influence of insulin, beta-estradiol, dexamethasone and thyroid hormone on the secretion of coagulant and anticoagulant proteins by HepG2 cells.
Thrombosis and haemostasis 1995;74(2):686-92.
1995: Jansen P M; Boermeester M A; Fischer E; de Jong I W; van der Poll T; Moldawer L L; Hack C E; Lowry S F
Contribution of interleukin-1 to activation of coagulation and fibrinolysis, neutrophil degranulation, and the release of secretory-type phospholipase A2 in sepsis: studies in nonhuman primates after interleukin-1 alpha administration and during lethal bacteremia.
Blood 1995;86(3):1027-34.
1995: Boermeester M A; van Leeuwen P A; Coyle S M; Wolbink G J; Hack C E; Lowry S F
Interleukin-1 blockade attenuates mediator release and dysregulation of the hemostatic mechanism during human sepsis.
Archives of surgery (Chicago, Ill. : 1960) 1995;130(7):739-48.
1995: Jansen P M; van Damme J; Put W; de Jong I W; Taylor F B; Hack C E
Monocyte chemotactic protein 1 is released during lethal and sublethal bacteremia in baboons.
The Journal of infectious diseases 1995;171(6):1640-2.
1995: Biemond B J; Levi M; Ten Cate H; Van der Poll T; Büller H R; Hack C E; Ten Cate J W
Plasminogen activator and plasminogen activator inhibitor I release during experimental endotoxaemia in chimpanzees: effect of interventions in the cytokine and coagulation cascades.
Clinical science (London, England : 1979) 1995;88(5):587-94.
1995: van der Poll T; Levi M; ten Cate H; Jansen J; Biemond B J; Haagmans B L; Eerenberg A; van Deventer S J; Hack C E; ten Cate J W
Effect of postponed treatment with an anti-tumour necrosis factor (TNF) F(ab')2 fragment on endotoxin-induced cytokine and neutrophil responses in chimpanzees.
Clinical and experimental immunology 1995;100(1):21-5.
1995: Kummer J A; Kamp A M; Tadema T M; Vos W; Meijer C J; Hack C E
Localization and identification of granzymes A and B-expressing cells in normal human lymphoid tissue and peripheral blood.
Clinical and experimental immunology 1995;100(1):164-72.
1995: Raijmakers P G; Groeneveld A B; Rauwerda J A; Schneider A J; Teule G J; Hack C E; Thijs L G
Transient increase in interleukin-8 and pulmonary microvascular permeability following aortic surgery.
American journal of respiratory and critical care medicine 1995;151(3 Pt 1):698-705.
1995: Wuillemin W A; Minnema M; Meijers J C; Roem D; Eerenberg A J; Nuijens J H; ten Cate H; Hack C E
Inactivation of factor XIa in human plasma assessed by measuring factor XIa-protease inhibitor complexes: major role for C1-inhibitor.
Blood 1995;85(6):1517-26.
1995: Kummer J A; Wever P C; Kamp A M; ten Berge I J; Hack C E; Weening J J
Expression of granzyme A and B proteins by cytotoxic lymphocytes involved in acute renal allograft rejection.
Kidney international 1995;47(1):70-7.
1995: Parlevliet K J; Bemelman F J; Yong S L; Hack C E; Surachno J; Wilmink J M; ten Berge I J; Schellekens P T
Toxicity of OKT3 increases with dosage: a controlled study in renal transplant recipients.
Transplant international : official journal of the European Society for Organ Transplantation 1995;8(2):141-6.
1995: Wagstaff J; Baars J W; Wolbink G J; Hoekman K; Eerenberg-Belmer A J; Hack C E
Renal cell carcinoma and interleukin-2: a review.
European journal of cancer (Oxford, England : 1990) 1995;31A(3):401-8.
1994: Bemelman F J; Jansen J; van der Poll T; Hack C E; van Deventer S J; ten Berge R J
Increased levels of sTNF receptors following OKT3 treatment.
Transplantation proceedings 1994;26(6):3094-5.
1994: Tak P P; Kummer J A; Hack C E; Daha M R; Smeets T J; Erkelens G W; Meinders A E; Kluin P M; Breedveld F C
Granzyme-positive cytotoxic cells are specifically increased in early rheumatoid synovial tissue.
Arthritis and rheumatism 1994;37(12):1735-43.
1994: Baars J W; Wolbink G J; Hart M H; Hack C E; Eerenberg-Belmer A J; Pinedo H M; Wagstaff J
The release of interleukin-8 during intravenous bolus treatment with interleukin-2.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1994;5(10):929-34.
1994: Bemelman F J; Buysmann S; Wilmink J M; Surachno S; Hack C E; Schellekens P T; ten Berge R J
Effects of divided doses of steroids on side effects, cytokines, and activation of complement and granulocytes, coagulation and fibrinolysis after OKT3.
Transplantation proceedings 1994;26(6):3096-7.
1994: de Haas M; Kerst J M; van der Schoot C E; Calafat J; Hack C E; Nuijens J H; Roos D; van Oers R H; von dem Borne A E
Granulocyte colony-stimulating factor administration to healthy volunteers: analysis of the immediate activating effects on circulating neutrophils.
Blood 1994;84(11):3885-94.
1994: Kummer J A; Tak P P; Brinkman B M; van Tilborg A A; Kamp A M; Verweij C L; Daha M R; Meinders A E; Hack C E; Breedveld F C
Expression of granzymes A and B in synovial tissue from patients with rheumatoid arthritis and osteoarthritis.
Clinical immunology and immunopathology 1994;73(1):88-95.
1994: van der Linden P W; Hack C E; Struyvenberg A; Kees van der Zwan J
Intentional diagnostic sting challenges: an important medical issue.
The Journal of allergy and clinical immunology 1994;94(3 Pt 1):563-4.
1994: van der Linden P W; Hack C E; Struyvenberg A; van der Zwan J K
Insect-sting challenge in 324 subjects with a previous anaphylactic reaction: current criteria for insect-venom hypersensitivity do not predict the occurrence and the severity of anaphylaxis.
The Journal of allergy and clinical immunology 1994;94(2 Pt 1):151-9.
1994: van der Poll T; Levi M; Hack C E; ten Cate H; van Deventer S J; Eerenberg A J; de Groot E R; Jansen J; Gallati H; Büller H R
Elimination of interleukin 6 attenuates coagulation activation in experimental endotoxemia in chimpanzees.
The Journal of experimental medicine 1994;179(4):1253-9.
1994: Kuipers B; van der Poll T; Levi M; van Deventer S J; ten Cate H; Imai Y; Hack C E; ten Cate J W
Platelet-activating factor antagonist TCV-309 attenuates the induction of the cytokine network in experimental endotoxemia in chimpanzees.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(5):2438-46.
1994: Ogilvie A C; Baars J W; Eerenberg A J; Hack C E; Pinedo H M; Thijs L G; Wagstaff J
A pilot study to evaluate the effects of C1 esterase inhibitor on the toxicity of high-dose interleukin 2.
British journal of cancer 1994;69(3):596-8.
1994: van der Poll T; Levi M; van Deventer S J; ten Cate H; Haagmans B L; Biemond B J; Büller H R; Hack C E; ten Cate J W
Differential effects of anti-tumor necrosis factor monoclonal antibodies on systemic inflammatory responses in experimental endotoxemia in chimpanzees.
Blood 1994;83(2):446-51.
1994: Levi M; ten Cate H; Bauer K A; van der Poll T; Edgington T S; Büller H R; van Deventer S J; Hack C E; ten Cate J W; Rosenberg R D
Inhibition of endotoxin-induced activation of coagulation and fibrinolysis by pentoxifylline or by a monoclonal anti-tissue factor antibody in chimpanzees.
The Journal of clinical investigation 1994;93(1):114-20.
1994: Hack C E; Ogilvie A C; Eisele B; Jansen P M; Wagstaff J; Thijs L G
Initial studies on the administration of C1-esterase inhibitor to patients with septic shock or with a vascular leak syndrome induced by interleukin-2 therapy.
Progress in clinical and biological research 1994;388():335-57.
1993: Eldering E; Huijbregts C C; Nuijens J H; Hack C E
The balance between inhibition and substrate-type reactions of recombinant C1 inhibitor P5/P3 variants.
Behring Institute Mitteilungen 1993;(93):125-30.
1993: de Boer J P; Creasey A A; Chang A; Abbink J J; Roem D; Eerenberg A J; Hack C E; Taylor F B
Alpha-2-macroglobulin functions as an inhibitor of fibrinolytic, clotting, and neutrophilic proteinases in sepsis: studies using a baboon model.
Infection and immunity 1993;61(12):5035-43.
1993: de Boer J P; Creasey A A; Chang A; Roem D; Eerenberg A J; Hack C E; Taylor F B
Activation of the complement system in baboons challenged with live Escherichia coli: correlation with mortality and evidence for a biphasic activation pattern.
Infection and immunity 1993;61(10):4293-301.
1993: van der Linden P W; Hack C E; Struyvenberg A; van der Zwan J C
[Anaphylactic reactions following insect stings: clinical aspects, course and treatment]
Nederlands tijdschrift voor geneeskunde 1993;137(43):2194-9.
1993: van der Linden P W; Hack C E; Struyvenberg A; van der Zwan J C
[Pathogenesis of anaphylactic symptoms following an insect sting]
Nederlands tijdschrift voor geneeskunde 1993;137(43):2188-94.
1993: van der Linden P W; Hack C E; Eerenberg A J; Struyvenberg A; van der Zwan J K
Activation of the contact system in insect-sting anaphylaxis: association with the development of angioedema and shock.
Blood 1993;82(6):1732-9.
1993: Dolman K M; Stegeman C A; van de Wiel B A; Hack C E; von dem Borne A E; Kallenberg C G; Goldschmeding R
Relevance of classic anti-neutrophil cytoplasmic autoantibody (C-ANCA)-mediated inhibition of proteinase 3-alpha 1-antitrypsin complexation to disease activity in Wegener's granulomatosis.
Clinical and experimental immunology 1993;93(3):405-10.
1993: van der Linden P W; Hack C E; Struyvenberg A; Roem D; Brouwer M C; de Boer J P; van der Zwan J K
Controlled insect-sting challenge in 55 patients: correlation between activation of plasminogen and the development of anaphylactic shock.
Blood 1993;82(6):1740-8.
1993: van Leenen D; van der Poll T; Levi M; ten Cate H; van Deventer S J; Hack C E; Aarden L A; ten Cate J W
Pentoxifylline attenuates neutrophil activation in experimental endotoxemia in chimpanzees.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(4):2318-25.
1993: Kummer J A; Kamp A M; van Katwijk M; Brakenhoff J P; Radosevic K; van Leeuwen A M; Borst J; Verweij C L; Hack C E
Production and characterization of monoclonal antibodies raised against recombinant human granzymes A and B and showing cross reactions with the natural proteins.
Journal of immunological methods 1993;163(1):77-83.
1993: Wolbink G J; Bollen J; Baars J W; ten Berge R J; Swaak A J; Paardekooper J; Hack C E
Application of a monoclonal antibody against a neoepitope on activated C4 in an ELISA for the quantification of complement activation via the classical pathway.
Journal of immunological methods 1993;163(1):67-76.
1993: Raasveld M H; Bemelman F J; Schellekens P T; van Diepen F N; van Dongen A; van Royen E A; Hack C E; ten Berge I J
Complement activation during OKT3 treatment: a possible explanation for respiratory side effects.
Kidney international 1993;43(5):1140-9.
1993: Eldering E; Huijbregts C C; Nuijens J H; Verhoeven A J; Hack C E
Recombinant C1 inhibitor P5/P3 variants display resistance to catalytic inactivation by stimulated neutrophils.
The Journal of clinical investigation 1993;91(3):1035-43.
1993: ten Berge R J; Raasveld M H; van Diepen F N; Hack C E
Activation of coagulation and fibrinolysis during treatment with OKT3.
Transplantation proceedings 1993;25(1 Pt 1):566-7.
1993: Abbink J J; Kamp A M; Nuijens J H; Swaak T J; Hack C E
Proteolytic inactivation of alpha 1-antitrypsin and alpha 1-antichymotrypsin by neutrophils in arthritic joints.
Arthritis and rheumatism 1993;36(2):168-80.
1993: van Deventer S J; Hart M; van der Poll T; Hack C E; Aarden L A
Endotoxin and tumor necrosis factor-alpha-induced interleukin-8 release in humans.
The Journal of infectious diseases 1993;167(2):461-54.
1993: van der Linden P W; Struyvenberg A; Kraaijenhagen R J; Hack C E; van der Zwan J K
Anaphylactic shock after insect-sting challenge in 138 persons with a previous insect-sting reaction.
Annals of internal medicine 1993;118(3):161-8.
1993: Levi M; Roem D; Kamp A M; de Boer J P; Hack C E; ten Cate J W
Assessment of the relative contribution of different protease inhibitors to the inhibition of plasmin in vivo.
Thrombosis and haemostasis 1993;69(2):141-6.
1993: Cugno M; Hack C E; de Boer J P; Eerenberg A J; Agostoni A; Cicardi M
Generation of plasmin during acute attacks of hereditary angioedema.
The Journal of laboratory and clinical medicine 1993;121(1):38-43.
1993: Hessing M; Paardekooper J; Hack C E
Separation of different forms of the fourth component of human complement by fast protein liquid chromatography.
Journal of immunological methods 1993;157(1-2):39-48.
1993: de Smet B J; de Boer J P; Agterberg J; Rigter G; Bleeker W K; Hack C E
Clearance of human native, proteinase-complexed, and proteolytically inactivated C1-inhibitor in rats.
Blood 1993;81(1):56-61.
1993: de Boer J P; Creasy A A; Chang A; Roem D; Brouwer M C; Eerenberg A J; Hack C E; Taylor F B
Activation patterns of coagulation and fibrinolysis in baboons following infusion with lethal or sublethal dose of Escherichia coli.
Circulatory shock 1993;39(1):59-67.
1993: Dolman K M; van de Wiel B A; Kam C M; Kerrigan J E; Hack C E; von dem Borne A E; Powers J C; Goldschmeding R
Proteinase 3: substrate specificity and possible pathogenetic effect of Wegener's granulomatosis autoantibodies (c-ANCA) by dysregulation of the enzyme.
Advances in experimental medicine and biology 1993;336():55-60.
1993: Thijs L G; de Boer J P; de Groot M C; Hack C E
Coagulation disorders in septic shock.
Intensive care medicine 1993;19 Suppl 1():S8-15.
1993: Hack C E; Ogilvie A C; Eisele B; Eerenberg A J; Wagstaff J; Thijs L G
C1-inhibitor substitution therapy in septic shock and in the vascular leak syndrome induced by high doses of interleukin-2.
Intensive care medicine 1993;19 Suppl 1():S19-28.
1992: Dolman K M; van de Wiel B A; Kam C M; Abbink J J; Hack C E; Sonnenberg A; Powers J C; von dem Borne A E; Goldschmeding R
Determination of proteinase 3-alpha 1-antitrypsin complexes in inflammatory fluids.
FEBS letters 1992;314(2):117-21.
1992: van de Wiel B A; Dolman K M; van der Meer-Gerritsen C H; Hack C E; von dem Borne A E; Goldschmeding R
Interference of Wegener's granulomatosis autoantibodies with neutrophil Proteinase 3 activity.
Clinical and experimental immunology 1992;90(3):409-14.
1992: Abbink J J; Kamp A M; Nuijens J H; Erenberg A J; Swaak A J; Hack C E
Relative contribution of contact and complement activation to inflammatory reactions in arthritic joints.
Annals of the rheumatic diseases 1992;51(10):1123-8.
1992: Baars J W; de Boer J P; Wagstaff J; Roem D; Eerenberg-Belmer A J; Nauta J; Pinedo H M; Hack C E
Interleukin-2 induces activation of coagulation and fibrinolysis: resemblance to the changes seen during experimental endotoxaemia.
British journal of haematology 1992;82(2):295-301.
1992: de Boer J P; Wolbink G J; Thijs L G; Baars J W; Wagstaff J; Hack C E
Interplay of complement and cytokines in the pathogenesis of septic shock.
Immunopharmacology 1992;24(2):135-48.
1992: Raasveld M H; Hack C E; ten Berge I J
Activation of coagulation and fibrinolysis following OKT3 administration to renal transplant recipients: association with distinct mediators.
Thrombosis and haemostasis 1992;68(3):264-7.
1992: Kummer J A; Abbink J J; de Boer J P; Roem D; Nieuwenhuys E J; Kamp A M; Swaak T J; Hack C E
Analysis of intraarticular fibrinolytic pathways in patients with inflammatory and noninflammatory joint diseases.
Arthritis and rheumatism 1992;35(8):884-93.
1992: van der Linden P W; Hack C E; Poortman J; Vivié-Kipp Y C; Struyvenberg A; van der Zwan J K
Insect-sting challenge in 138 patients: relation between clinical severity of anaphylaxis and mast cell activation.
The Journal of allergy and clinical immunology 1992;90(1):110-8.
1992: Hack C E; Hart M; van Schijndel R J; Eerenberg A J; Nuijens J H; Thijs L G; Aarden L A
Interleukin-8 in sepsis: relation to shock and inflammatory mediators.
Infection and immunity 1992;60(7):2835-42.
1992: Eikelenboom P; Hack C E; Kamphorst W; Rozemuller J M
Distribution pattern and functional state of complement proteins and alpha 1-antichymotrypsin in cerebral beta/A4 deposits in Alzheimer's disease.
Research in immunology 1992;143(6):617-20.
1992: Dors D M; Nuijens J H; Huijbregts C C; Hack C E
A novel sensitive assay for functional factor XII based on the generation of kallikrein-C1-inhibitor complexes in factor XII-deficient plasma by glass-bound factor XII.
Thrombosis and haemostasis 1992;67(6):644-8.
1992: Raasveld M H; Surachno S; Hack C E; ten Berge R J
Thromboembolic complications and dose of monoclonal OKT3 antibody.
Lancet 1992;339(8805):1363-4.
1992: Eldering E; Huijbregts C C; Lubbers Y T; Longstaff C; Hack C E
Characterization of recombinant C1 inhibitor P1 variants.
The Journal of biological chemistry 1992;267(10):7013-20.
1992: Baars J W; Wagstaff J; Hack C E; Wolbink G J; Eerenberg-Belmer A J; Pinedo H M
Angioneurotic oedema and urticaria during therapy with interleukin-2 (IL-2).
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1992;3(3):243-4.
1992: Nuijens J H; Abbink J J; Wachtfogel Y T; Colman R W; Eerenberg A J; Dors D; Kamp A J; Strack van Schijndel R J; Thijs L G; Hack C E
Plasma elastase alpha 1-antitrypsin and lactoferrin in sepsis: evidence for neutrophils as mediators in fatal sepsis.
The Journal of laboratory and clinical medicine 1992;119(2):159-68.
1992: Bleeker W K; Agterberg J; Rigter G; Hack C E; Gool J V
Protective effect of antithrombin III in acute experimental pancreatitis in rats.
Digestive diseases and sciences 1992;37(2):280-5.
1992: van der Poll T; van Deventer S J; Hack C E; Wolbink G J; Aarden L A; Büller H R; ten Cate J W
Effects on leukocytes after injection of tumor necrosis factor into healthy humans.
Blood 1992;79(3):693-8.
1992: Hack C E; Voerman H J; Eisele B; Keinecke H O; Nuijens J H; Eerenberg A J; Ogilvie A; Strack van Schijndel R J; Delvos U; Thijs L G
C1-esterase inhibitor substitution in sepsis.
Lancet 1992;339(8789):378.
1992: Baars J W; Hack C E; Wagstaff J; Eerenberg-Belmer A J; Wolbink G J; Thijs L G; Strack van Schijndel R J; van der Vall H L; Pinedo H M
The activation of polymorphonuclear neutrophils and the complement system during immunotherapy with recombinant interleukin-2.
British journal of cancer 1992;65(1):96-101.
1992: Levi M; de Boer J P; Roem D; ten Cate J W; Hack C E
Plasminogen activation in vivo upon intravenous infusion of DDAVP. Quantitative assessment of plasmin-alpha 2-antiplasmin complex with a novel monoclonal antibody based radioimmunoassay.
Thrombosis and haemostasis 1992;67(1):111-6.
1992: Levi M; Hack C E; de Boer J P; Brandjes D P; Büller H R; ten Cate J W
Contact system dependent fibrinolytic activity in vivo: observations in healthy subjects and factor XII deficient patients.
Agents and actions. Supplements 1992;38 ( Pt 2)():292-8.
1991: Abbink J J; Kamp A M; Swaak A J; Hack C E
Production of monoclonal antibodies against inactivated alpha 1-antitrypsin. Cross-reactivity with complexed alpha 1-antitrypsin and application in an assay to determine inactivated and complexed alpha 1-antitrypsin in biological fluids.
Journal of immunological methods 1991;143(2):197-208.
1991: Levi M; Hack C E; de Boer J P; Brandjes D P; Büller H R; ten Cate J W
Reduction of contact activation related fibrinolytic activity in factor XII deficient patients. Further evidence for the role of the contact system in fibrinolysis in vivo.
The Journal of clinical investigation 1991;88(4):1155-60.
1991: Abbink J J; Kamp A M; Nieuwenhuys E J; Nuijens J H; Swaak A J; Hack C E
Predominant role of neutrophils in the inactivation of alpha 2-macroglobulin in arthritic joints.
Arthritis and rheumatism 1991;34(9):1139-50.
1991: van der Poll T; Levi M; Büller H R; van Deventer S J; de Boer J P; Hack C E; ten Cate J W
Fibrinolytic response to tumor necrosis factor in healthy subjects.
The Journal of experimental medicine 1991;174(3):729-32.
1991: Hintzen R Q; de Jong R; Hack C E; Chamuleau M; de Vries E F; ten Berge I J; Borst J; van Lier R A
A soluble form of the human T cell differentiation antigen CD27 is released after triggering of the TCR/CD3 complex.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(1):29-35.
1991: Nijsten M W; Hack C E; Helle M; ten Duis H J; Klasen H J; Aarden L A
Interleukin-6 and its relation to the humoral immune response and clinical parameters in burned patients.
Surgery 1991;109(6):761-7.
1991: Hack C E; Wagstaff J; Strack van Schijndel R J; Eerenberg A J; Pinedo H M; Thijs L G; Nuijens J H
Studies on the contact system of coagulation during therapy with high doses of recombinant IL-2: implications for septic shock.
Thrombosis and haemostasis 1991;65(5):497-503.
1991: Kleinveld H A; Sluiter W; Boonman A M; Swaak A J; Hack C E; Koster J F
Differential stimulation by oxygen-free-radical-altered immunoglobulin G of the production of superoxide and hydrogen peroxide by human polymorphonuclear leucocytes.
Clinical science (London, England : 1979) 1991;80(4):385-91.
1991: de Boer J P; Abbink J J; Brouwer M C; Meijer C; Roem D; Voorn G P; Lambers J W; van Mourik J A; Hack C E
PAI-1 synthesis in the human hepatoma cell line HepG2 is increased by cytokines--evidence that the liver contributes to acute phase behaviour of PAI-1.
Thrombosis and haemostasis 1991;65(2):181-5.
1991: Abbink J J; Nuijens J H; Eerenberg A J; Huijbregts C C; Strack van Schijndel R J; Thijs L G; Hack C E
Quantification of functional and inactivated alpha 2-macroglobulin in sepsis.
Thrombosis and haemostasis 1991;65(1):32-9.
1991: Rozemuller J M; Abbink J J; Kamp A M; Stam F C; Hack C E; Eikelenboom P
Distribution pattern and functional state of alpha 1-antichymotrypsin in plaques and vascular amyloid in Alzheimer's disease. A immunohistochemical study with monoclonal antibodies against native and inactivated alpha 1-antichymotrypsin.
Acta neuropathologica 1991;82(3):200-7.
1990: van der Linden P W; Hack C E; Kerckhaert J A; Struyvenberg A; van der Zwan J C
Preliminary report: complement activation in wasp-sting anaphylaxis.
Lancet 1990;336(8720):904-6.
1990: Hoekzema R; Swaak A J; Brouwer M C; van Rooijen A; Nieuwenhuys E J; Hack C E
Significance of low molecular weight C1q in systemic lupus erythematosus.
Annals of the rheumatic diseases 1990;49(9):698-704.
1990: van der Poll T; Büller H R; ten Cate H; Wortel C H; Bauer K A; van Deventer S J; Hack C E; Sauerwein H P; Rosenberg R D; ten Cate J W
Activation of coagulation after administration of tumor necrosis factor to normal subjects.
The New England journal of medicine 1990;322(23):1622-7.
1990: Hack C E; Paardekooper J; Van Milligen F
Demonstration in human plasma of a form of C3 that has the conformation of "C3b-like C3".
Journal of immunology (Baltimore, Md. : 1950) 1990;144(11):4249-55.
1990: Hack C E; Abbink J J; Nuijens J H
[Serine protease inhibitors (serpins); regulators of coagulation and inflammation reactions with therapeutic potential]
Nederlands tijdschrift voor geneeskunde 1990;134(21):1035-9.
1990: Thijs L G; Hack C E; Strack van Schijndel R J; Nuijens J H; Wolbink G J; Eerenberg-Belmer A J; Van der Vall H; Wagstaff J
Activation of the complement system during immunotherapy with recombinant IL-2. Relation to the development of side effects.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(6):2419-24.
1990: Hoogerwerf M; Weening R S; Hack C E; Roos D
Complement fragments C3b and iC3b coupled to latex induce a respiratory burst in human neutrophils.
Molecular immunology 1990;27(2):159-67.
1990: Hack C E; Nuijens J H; Strack van Schijndel R J; Abbink J J; Eerenberg A J; Thijs L G
A model for the interplay of inflammatory mediators in sepsis--a study in 48 patients.
Intensive care medicine 1990;16 Suppl 3():S187-91.
1989: Hack C E; De Groot E R; Felt-Bersma R J; Nuijens J H; Strack Van Schijndel R J; Eerenberg-Belmer A J; Thijs L G; Aarden L A
Increased plasma levels of interleukin-6 in sepsis.
Blood 1989;74(5):1704-10.
1989: Nuijens J H; Eerenberg-Belmer A J; Huijbregts C C; Schreuder W O; Felt-Bersma R J; Abbink J J; Thijs L G; Hack C E
Proteolytic inactivation of plasma C1- inhibitor in sepsis.
The Journal of clinical investigation 1989;84(2):443-50.
1989: Thijs L G; Hack C E; Strack van Schijndel R J; Nuijens J H; Wolbink G J; Eerenberg-Belmer A J; van der Vall H; Wagstaff J
Complement activation and high-dose of interleukin-2.
Lancet 1989;2(8659):395.
1989: Nuijens J H; Huijbregts C C; Eerenberg-Belmer A J; Meijers J C; Bouma B N; Hack C E
Activation of the contact system of coagulation by a monoclonal antibody directed against a neodeterminant in the heavy chain region of human coagulation factor XII (Hageman factor).
The Journal of biological chemistry 1989;264(22):12941-9.
1989: Wagstaff J; Vermorken J B; Schwartsmann G; Scheper R J; Hack C E; Nuijens J H; Eerenberg-Belmer A J; Pinedo H M
A progress report of a phase I study of interferon-gamma and interleukin-2 and some comments on the mechanism of the toxicity due to interleukin-2.
Cancer treatment reviews 1989;16 Suppl A():105-9.
1989: Hack C E; Nuijens J H; Felt-Bersma R J; Schreuder W O; Eerenberg-Belmer A J; Paardekooper J; Bronsveld W; Thijs L G
Elevated plasma levels of the anaphylatoxins C3a and C4a are associated with a fatal outcome in sepsis.
The American journal of medicine 1989;86(1):20-6.
1989: Hoekzema R; Brouwer M C; de Graeff-Meeder E R; van Helden H P; Hack C E
Biosynthesis of normal and low-molecular-mass complement component C1q by cultured human monocytes and macrophages.
The Biochemical journal 1989;257(2):477-86.
1989: Kleinveld H A; Swaak A J; Hack C E; Koster J F
Interactions between oxygen free radicals and proteins. Implications for rheumatoid arthritis. An overview.
Scandinavian journal of rheumatology 1989;18(6):341-52.
1989: Thijs L G; Hack C E; Nuyens J H; Groeneveld A B
Peripheral circulation in septic shock.
Progress in clinical and biological research 1989;308():163-74.
1989: Eikelenboom P; Hack C E; Rozemuller J M; Stam F C
Complement activation in amyloid plaques in Alzheimer's dementia.
Virchows Archiv. B, Cell pathology including molecular pathology 1989;56(4):259-62.
1988: Nuijens J H; Huijbregts C C; Eerenberg-Belmer A J; Abbink J J; Strack van Schijndel R J; Felt-Bersma R J; Thijs L G; Hack C E
Quantification of plasma factor XIIa-Cl(-)-inhibitor and kallikrein-Cl(-)-inhibitor complexes in sepsis.
Blood 1988;72(6):1841-8.
1988: Hack C E; Paardekooper J; Smeenk R J; Abbink J; Eerenberg A J; Nuijens J H
Disruption of the internal thioester bond in the third component of complement (C3) results in the exposure of neodeterminants also present on activation products of C3. An analysis with monoclonal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(5):1602-9.
1988: Eldering E; Nuijens J H; Hack C E
Expression of functional human C1 inhibitor in COS cells.
The Journal of biological chemistry 1988;263(24):11776-9.
1988: Hoekzema R; Martens M; Brouwer M C; Hack C E
The distortive mechanism for the activation of complement component C1 supported by studies with a monoclonal antibody against the "arms" of C1q.
Molecular immunology 1988;25(5):485-94.
1988: Hack C E; Paardekooper J; Eerenberg A J; Navis G O; Nijsten M W; Thijs L G; Nuijens J H
A modified competitive inhibition radioimmunoassay for the detection of C3a. Use of 125I-C3 instead of 125I-C3a.
Journal of immunological methods 1988;108(1-2):77-84.
1988: Kleinveld H A; Hack C E; Swaak A J; van Noort W L; van Eijk H G; Koster J F
Covalent cross-links in oxygen free radical altered human immunoglobulin G.
Scandinavian journal of rheumatology. Supplement 1988;75():157-63.
1987: Nijsten M W; de Groot E R; ten Duis H J; Klasen H J; Hack C E; Aarden L A
Serum levels of interleukin-6 and acute phase responses.
Lancet 1987;2(8564):921.
1987: Nuijens J H; Huijbregts C C; Cohen M; Navis G O; de Vries A; Eerenberg A J; Bakker J C; Hack C E
Detection of activation of the contact system of coagulation in vitro and in vivo: quantitation of activated Hageman factor-C-1-inhibitor and kallikrein-C-1-inhibitor complexes by specific radioimmunoassays.
Thrombosis and haemostasis 1987;58(2):778-85.
1987: Nuijens J H; Huijbregts C C; van Mierlo G M; Hack C E
Inactivation of C-1 inhibitor by proteases: demonstration by a monoclonal antibody of a neodeterminant on inactivated, non-complexed C-1 inhibitor.
Immunology 1987;61(3):387-9.

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