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Jörg Hacker

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TOP 3
Andreas Leimbach; Jörg Hacker; Ulrich Dobrindt
E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity.
Péter Zsolt Fekete; Gerhard Gottschalk; Jörg Hacker; Gabriele Blum-Oehler; Elzbieta Brzuszkiewicz; Ferenc Olasz; Mónika Szabó; Béla Nagy
DNA sequence analysis of the composite plasmid pTC conferring virulence and antimicrobial resistance for porcine enterotoxigenic Escherichia coli.
György Schneider; Valéria Szijártó; Ulrich Dobrindt; Levente Emody; Bianca Hochhut; Barbara Middendorf; Jörg Hacker
Mobilisation and remobilisation of a large archetypal pathogenicity island of uropathogenic Escherichia coli in vitro support the role of conjugation for horizontal transfer of genomic islands.

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All Publications

2013: Andreas Leimbach; Jörg Hacker; Ulrich Dobrindt
E. coli as an All-Rounder: The Thin Line Between Commensalism and Pathogenicity.
Current topics in microbiology and immunology 2013;358():3-32.
2012: Péter Zsolt Fekete; Gerhard Gottschalk; Jörg Hacker; Gabriele Blum-Oehler; Elzbieta Brzuszkiewicz; Ferenc Olasz; Mónika Szabó; Béla Nagy
DNA sequence analysis of the composite plasmid pTC conferring virulence and antimicrobial resistance for porcine enterotoxigenic Escherichia coli.
International journal of medical microbiology : IJMM 2012;302(1):4-9.
2011: György Schneider; Valéria Szijártó; Ulrich Dobrindt; Levente Emody; Bianca Hochhut; Barbara Middendorf; Jörg Hacker
Mobilisation and remobilisation of a large archetypal pathogenicity island of uropathogenic Escherichia coli in vitro support the role of conjugation for horizontal transfer of genomic islands.
BMC microbiology 2011;11():210.
2010: Philippe Bauchart; Pierre Germon; Annie Brée; Eric Oswald; Jörg Hacker; Ulrich Dobrindt
Pathogenomic comparison of human extraintestinal and avian pathogenic Escherichia coli--search for factors involved in host specificity or zoonotic potential.
Microbial pathogenesis 2010;49(3):105-15.
2010: Ulrich Dobrindt; Jörg Hacker
Nosocomial infections and their control.
International journal of medical microbiology : IJMM 2010;300(6):341.
2010: Timo A Lehti; Philippe Bauchart; Johanna Heikkinen; Jörg Hacker; Timo K Korhonen; Ulrich Dobrindt; Benita Westerlund-Wikström
Mat fimbriae promote biofilm formation by meningitis-associated Escherichia coli.
Microbiology (Reading, England) 2010;156(Pt 8):2408-17.
2010: Ulrich Dobrindt; Jaroslaw Zdziarski; Ellaine Salvador; Jörg Hacker
Bacterial genome plasticity and its impact on adaptation during persistent infection.
International journal of medical microbiology : IJMM 2010;300(6):363-6.
2010: Ulrich Dobrindt; M Geddam Chowdary; G Krumbholz; Jörg Hacker
Genome dynamics and its impact on evolution of Escherichia coli.
Medical microbiology and immunology 2010;199(3):145-54.
2010: Torben Friedrich; Sven Rahmann; Wilfried Weigel; Wolfgang Rabsch; Angelika Fruth; Eliora Ron; Florian Gunzer; Thomas Dandekar; Jörg Hacker; Tobias Müller; Ulrich Dobrindt
High-throughput microarray technology in diagnostics of enterobacteria based on genome-wide probe selection and regression analysis.
BMC genomics 2010;11():591.
2010: Jaroslaw Zdziarski; Elzbieta Brzuszkiewicz; Björn Wullt; Heiko Liesegang; Dvora Biran; Birgit Voigt; Jenny Grönberg-Hernandez; Bryndis Ragnarsdottir; Michael Hecker; Eliora Z Ron; Rolf Daniel; Gerhard Gottschalk; Jörg Hacker; Catharina Svanborg; Ulrich Dobrindt
Host imprints on bacterial genomes--rapid, divergent evolution in individual patients.
PLoS pathogens 2010;6(8):e1001078.
2009: Johannes Putze; Claire Hennequin; Jean-Philippe Nougayrède; Wenlan Zhang; Stefan Homburg; Helge Karch; Marie-Agnés Bringer; Corinne Fayolle; Elisabeth Carniel; Wolfgang Rabsch; Tobias A Oelschlaeger; Eric Oswald; Christiane Forestier; Jörg Hacker; Ulrich Dobrindt
Genetic structure and distribution of the colibactin genomic island among members of the family Enterobacteriaceae.
Infection and immunity 2009;77(11):4696-703.
2009: Elzbieta Brzuszkiewicz; Gerhard Gottschalk; E Ron; Jörg Hacker; Ulrich Dobrindt
Adaptation of Pathogenic E. coli to Various Niches: Genome Flexibility is the Key.
Genome dynamics 2009;6():110-25.
2008: Gábor Nagy; Tamás Palkovics; Andreas Otto; Harald Kusch; Béla Kocsis; Ulrich Dobrindt; Susanne Engelmann; Michael Hecker; Levente Emödy; Tibor Pál; Jörg Hacker
"Gently rough": the vaccine potential of a Salmonella enterica regulatory lipopolysaccharide mutant.
The Journal of infectious diseases 2008;198(11):1699-706.
2008: Karin Streker; Tina Schäfer; Christoph Freiberg; Heike Brötz-Oesterhelt; Jörg Hacker; Harald Labischinski; Knut Ohlsen
In vitro and in vivo validation of ligA and tarI as essential targets in Staphylococcus aureus.
Antimicrobial agents and chemotherapy 2008;52(12):4470-4.
2008: Ulrich Dobrindt; Jörg Hacker
Targeting virulence traits: potential strategies to combat extraintestinal pathogenic E. coli infections.
Current opinion in microbiology 2008;11(5):409-13.
2008: Caroline Wilde; Didier Mazel; Bianca Hochhut; Barbara Middendorf; Frédérique Le Roux; Elisabeth Carniel; Ulrich Dobrindt; Jörg Hacker
Delineation of the recombination sites necessary for integration of pathogenicity islands II and III into the Escherichia coli 536 chromosome.
Molecular microbiology 2008;68(1):139-51.
2008: Udo Lorenz; Christian Hüttinger; Tina Schäfer; Wilma Ziebuhr; Arnulf Thiede; Jörg Hacker; Susanne Engelmann; Michael Hecker; Knut Ohlsen
The alternative sigma factor sigma B of Staphylococcus aureus modulates virulence in experimental central venous catheter-related infections.
Microbes and infection / Institut Pasteur 2008;10(3):217-23.
2008: Jaroslaw Zdziarski; Catharina Svanborg; Björn Wullt; Jörg Hacker; Ulrich Dobrindt
Molecular basis of commensalism in the urinary tract: low virulence or virulence attenuation?
Infection and immunity 2008;76(2):695-703.
2007: Karsten Becker; Gabriele Bierbaum; Christof von Eiff; Susanne Engelmann; Friedrich Götz; Jörg Hacker; Michael Hecker; Georg Peters; Ralf Rosenstein; Wilma Ziebuhr
Understanding the physiology and adaptation of staphylococci: a post-genomic approach.
International journal of medical microbiology : IJMM 2007;297(7-8):483-501.
2007: Stefan Homburg; Eric Oswald; Jörg Hacker; Ulrich Dobrindt
Expression analysis of the colibactin gene cluster coding for a novel polyketide in Escherichia coli.
FEMS microbiology letters 2007;275(2):255-62.
2007: Carina Wagner; Abdul Salam Khan; Thilo Kamphausen; Bernd Schmausser; Can Unal; Udo Lorenz; Gunter Fischer; Jörg Hacker; Michael Steinert
Collagen binding protein Mip enables Legionella pneumophila to transmigrate through a barrier of NCI-H292 lung epithelial cells and extracellular matrix.
Cellular microbiology 2007;9(2):450-62.
2006: Martin Horstmann; Philipp Ehses; Kristian Schweimer; Michael Steinert; Thilo Kamphausen; Gunter Fischer; Jörg Hacker; Paul Rösch; Cornelius Faber
Domain motions of the Mip protein from Legionella pneumophila.
Biochemistry 2006;45(40):12303-11.
2006: Gábor Nagy; Vittoria Danino; Ulrich Dobrindt; Mark Pallen; Roy Chaudhuri; Levente Emödy; Jay Hinton; Jörg Hacker
Down-regulation of key virulence factors makes the Salmonella enterica serovar Typhimurium rfaH mutant a promising live-attenuated vaccine candidate.
Infection and immunity 2006;74(10):5914-25.
2006: Stephanie Theiss; Ganchimeg Ishdorj; Audrey Brenot; Marianne Kretschmar; Chung-Yu Lan; Thomas Nichterlein; Jörg Hacker; Santosh Nigam; Nina Agabian; Gerwald A Köhler
Inactivation of the phospholipase B gene PLB5 in wild-type Candida albicans reduces cell-associated phospholipase A2 activity and attenuates virulence.
International journal of medical microbiology : IJMM 2006;296(6):405-20.
2006: Elzbieta Brzuszkiewicz; Holger Bruggemann; Heiko Liesegang; Melanie Emmerth; Tobias Olschläger; Gábor Nagy; Kaj Albermann; Christian Wagner; Carmen Buchrieser; Levente Emody; Gerhard Gottschalk; Jörg Hacker; Ulrich Dobrindt
How to become a uropathogen: comparative genomic analysis of extraintestinal pathogenic Escherichia coli strains.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(34):12879-84.
2006: Jean-Philippe Nougayrède; Stefan Homburg; Frédéric Taieb; Michèle Boury; Elzbieta Brzuszkiewicz; Gerhard Gottschalk; Carmen Buchrieser; Jörg Hacker; Ulrich Dobrindt; Eric Oswald
Escherichia coli induces DNA double-strand breaks in eukaryotic cells.
Science (New York, N.Y.) 2006;313(5788):848-51.
2006: Antje Michel; Franziska Agerer; Christof R Hauck; Mathias Herrmann; Joachim Ullrich; Jörg Hacker; Knut Ohlsen
Global regulatory impact of ClpP protease of Staphylococcus aureus on regulons involved in virulence, oxidative stress response, autolysis, and DNA repair.
Journal of bacteriology 2006;188(16):5783-96.
2006: Bianca Hochhut; Caroline Wilde; Gudrun Balling; Barbara Middendorf; Ulrich Dobrindt; Elzbieta Brzuszkiewicz; Gerhard Gottschalk; Elisabeth Carniel; Jörg Hacker
Role of pathogenicity island-associated integrases in the genome plasticity of uropathogenic Escherichia coli strain 536.
Molecular microbiology 2006;61(3):584-95.
2006: Claudia M Müller; Ulrich Dobrindt; Gábor Nagy; Levente Emödy; Bernt Eric Uhlin; Jörg Hacker
Role of histone-like proteins H-NS and StpA in expression of virulence determinants of uropathogenic Escherichia coli.
Journal of bacteriology 2006;188(15):5428-38.
2006: Gábor Nagy; Artur Altenhoefer; Oliver Knapp; Elke Maier; Ulrich Dobrindt; Gabriele Blum-Oehler; Roland Benz; Levente Emody; Jörg Hacker
Both alpha-haemolysin determinants contribute to full virulence of uropathogenic Escherichia coli strain 536.
Microbes and infection / Institut Pasteur 2006;8(8):2006-12.
2006: Christoph F Batzilla; Shwan Rachid; Susanne Engelmann; Michael Hecker; Jörg Hacker; Wilma Ziebuhr
Impact of the accessory gene regulatory system (Agr) on extracellular proteins, codY expression and amino acid metabolism in Staphylococcus epidermidis.
Proteomics 2006;6(12):3602-13.
2006: Christophe Beloin; Kai Michaelis; Karin Lindner; Paolo Landini; Jörg Hacker; Jean-Marc Ghigo; Ulrich Dobrindt
The transcriptional antiterminator RfaH represses biofilm formation in Escherichia coli.
Journal of bacteriology 2006;188(4):1316-31.
2005: Sven Hammerschmidt; Jörg Hacker; Hans-Dieter Klenk
Threat of infection: microbes of high pathogenic potential--strategies for detection, control and eradication.
International journal of medical microbiology : IJMM 2005;295(3):141-51.
2005: Karin Streker; Christoph Freiberg; Harald Labischinski; Jörg Hacker; Knut Ohlsen
Staphylococcus aureus NfrA (SA0367) is a flavin mononucleotide-dependent NADPH oxidase involved in oxidative stress response.
Journal of bacteriology 2005;187(7):2249-56.
2005: Knut Ohlsen; Jörg Hacker
Infections in the elderly.
International journal of medical microbiology : IJMM 2005;294(8):471-2.
2005: Gábor Nagy; Ulrich Dobrindt; Lubomir Grozdanov; Jörg Hacker; Levente Emody
Transcriptional regulation through RfaH contributes to intestinal colonization by Escherichia coli.
FEMS microbiology letters 2005;244(1):173-80.
2005: Martin Horstmann; Thilo Kamphausen; Kristian Schweimer; Michael Steinert; Jörg Hacker; Axel Haase; Paul Rösch; Gunter Schweimer; Cornelius Faber
1H, 13C, 15N backbone and sidechain resonance assignment of Mip(77-213) the PPIase domain of the Legionella pneumophila Mip protein.
Journal of biomolecular NMR 2005;31(1):77-8.
2005: Bianca Hochhut; Ulrich Dobrindt; Jörg Hacker
Pathogenicity islands and their role in bacterial virulence and survival.
Contributions to microbiology 2005;12():234-54.
2004: Tobias A Oelschlaeger; Jörg Hacker
Impact of pathogenicity islands in bacterial diagnostics.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 2004;112(11-12):930-6.
2004: György Schneider; Ulrich Dobrindt; Holger Bruggemann; Gábor Nagy; Britta Janke; Gabriele Blum-Oehler; Carmen Buchrieser; Gerhard Gottschalk; Levente Emödy; Jörg Hacker
The pathogenicity island-associated K15 capsule determinant exhibits a novel genetic structure and correlates with virulence in uropathogenic Escherichia coli strain 536.
Infection and immunity 2004;72(10):5993-6001.
2004: Anne-Kathrin Ziebandt; Dörte Becher; Knut Ohlsen; Jörg Hacker; Michael Hecker; Susanne Engelmann
The influence of agr and sigmaB in growth phase dependent regulation of virulence factors in Staphylococcus aureus.
Proteomics 2004;4(10):3034-47.
2004: Marcela Fajardo; Michael Schleicher; Angelika A Noegel; Salvatore Bozzaro; Silke Killinger; Klaus Heuner; Jörg Hacker; Michael Steinert
Calnexin, calreticulin and cytoskeleton-associated proteins modulate uptake and growth of Legionella pneumophila in Dictyostelium discoideum.
Microbiology (Reading, England) 2004;150(Pt 9):2825-35.
2004: Petra Hess; Artur Altenhöfer; A Salam Khan; Neda Daryab; Kwang S Kim; Jörg Hacker; Tobias A Oelschlaeger
A Salmonella fim homologue in Citrobacter freundii mediates invasion in vitro and crossing of the blood-brain barrier in the rat pup model.
Infection and immunity 2004;72(9):5298-307.
2004: Lubomir Grozdanov; Carsten Raasch; Jürgen Schulze; Ulrich Sonnenborn; Gerhard Gottschalk; Jörg Hacker; Ulrich Dobrindt
Analysis of the genome structure of the nonpathogenic probiotic Escherichia coli strain Nissle 1917.
Journal of bacteriology 2004;186(16):5432-41.
2004: Gábor Nagy; Ulrich Dobrindt; Jörg Hacker; Levente Emödy
Oral immunization with an rfaH mutant elicits protection against salmonellosis in mice.
Infection and immunity 2004;72(7):4297-301.
2004: Barbara Middendorf; Bianca Hochhut; Kristina Leipold; Ulrich Dobrindt; Gabriele Blum-Oehler; Jörg Hacker
Instability of pathogenicity islands in uropathogenic Escherichia coli 536.
Journal of bacteriology 2004;186(10):3086-96.
2004: Ulrich Dobrindt; Bianca Hochhut; Ute Hentschel; Jörg Hacker
Genomic islands in pathogenic and environmental microorganisms.
Nature reviews. Microbiology 2004;2(5):414-24.
2004: Artur Altenhoefer; Sibylle Oswald; Ulrich Sonnenborn; Corinne Enders; Jürgen Schulze; Jörg Hacker; Tobias A Oelschlaeger
The probiotic Escherichia coli strain Nissle 1917 interferes with invasion of human intestinal epithelial cells by different enteroinvasive bacterial pathogens.
FEMS immunology and medical microbiology 2004;40(3):223-9.
2004: Jörg Hacker; Bianca Hochhut; Barbara Middendorf; György Schneider; Carmen Buchrieser; Gerhard Gottschalk; Ulrich Dobrindt
Pathogenomics of mobile genetic elements of toxigenic bacteria.
International journal of medical microbiology : IJMM 2004;293(7-8):453-61.
2003: Christian T Pabel; Joachim Vater; Christopher Wilde; Peter Franke; Jürgen Hofemeister; Barbara Adler; Gerhard Bringmann; Jörg Hacker; Ute Hentschel
Antimicrobial activities and matrix-assisted laser desorption/ionization mass spectrometry of Bacillus isolates from the marine sponge Aplysina aerophoba.
Marine biotechnology (New York, N.Y.) 2003;5(5):424-34.
2003: Jörg Hacker; Ute Hentschel; Ulrich Dobrindt
Prokaryotic chromosomes and disease.
Science (New York, N.Y.) 2003;301(5634):790-3.
2003: Péter Zsolt Fekete; György Schneider; Ferenc Olasz; Gabriele Blum-Oehler; Jörg Hacker; Béla Nagy
Detection of a plasmid-encoded pathogenicity island in F18+ enterotoxigenic and verotoxigenic Escherichia coli from weaned pigs.
International journal of medical microbiology : IJMM 2003;293(4):287-98.
2003: Rolf Köhler; Jörg Fanghänel; Bettina König; Edeltraud Lüneberg; Matthias Frosch; Jens-Ulrich Rahfeld; Rolf Hilgenfeld; Gunter Fischer; Jörg Hacker; Michael Steinert
Biochemical and functional analyses of the Mip protein: influence of the N-terminal half and of peptidylprolyl isomerase activity on the virulence of Legionella pneumophila.
Infection and immunity 2003;71(8):4389-97.
2003: Knut Ohlsen; Thomas A Ternes; Guido Werner; Ursula Wallner; Dirk Löffler; Wilma Ziebuhr; Wolfgang Witte; Jörg Hacker
Impact of antibiotics on conjugational resistance gene transfer in Staphylococcus aureus in sewage.
Environmental microbiology 2003;5(8):711-6.
2003: Cristina Gil-Lamaignere; Emmanuel Roilides; Jörg Hacker; Frank-Michael C Müller
Molecular typing for fungi--a critical review of the possibilities and limitations of currently and future methods.
Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases 2003;9(3):172-85.
2003: Roy Gross; Jörg Hacker; Werner Goebel
The Leopoldina international symposium on parasitism, commensalism and symbiosis--common themes, different outcome.
Molecular microbiology 2003;47(6):1749-58.
2003: Ulrich Dobrindt; Franziska Agerer; Kai Michaelis; Andreas Janka; Carmen Buchrieser; Martin Samuelson; Catharina Svanborg; Gerhard Gottschalk; Helge Karch; Jörg Hacker
Analysis of genome plasticity in pathogenic and commensal Escherichia coli isolates by use of DNA arrays.
Journal of bacteriology 2003;185(6):1831-40.
2003: Tobias A Oelschlaeger; D Zhang; Soren Schubert; Elisabeth Carniel; W Rabsch; Helge Karch; Jörg Hacker
The high-pathogenicity island is absent in human pathogens of Salmonella enterica subspecies I but present in isolates of subspecies III and VI.
Journal of bacteriology 2003;185(3):1107-11.
2003: Ute Hentschel; Lars Fieseler; M Wehrl; C Gernert; Michael Steinert; Jörg Hacker; Matthias Horn
Microbial diversity of marine sponges.
Progress in molecular and subcellular biology 2003;37():59-88.
2003: Jörg Hacker; Gabriele Blum-Oehler; Bianca Hochhut; Ulrich Dobrindt
The molecular basis of infectious diseases: pathogenicity islands and other mobile genetic elements. A review.
Acta microbiologica et immunologica Hungarica 2003;50(4):321-30.
2003: Jürgen Herbert Helbig; Bettina König; Henry Knospe; Birgit Bubert; Chao Yu; Christian Lück; Alan Riboldi-Tunnicliffe; Rolf Hilgenfeld; Enno Jacobs; Jörg Hacker; Gunter Fischer
The PPIase active site of Legionella pneumophila Mip protein is involved in the infection of eukaryotic host cells.
Biological chemistry 2003;384(1):125-37.
2003: Uri Gophna; Anat Parket; Jörg Hacker; Eliora Z Ron
A novel ColV plasmid encoding type IV pili.
Microbiology (Reading, England) 2003;149(Pt 1):177-84.
2003: Gabriele Blum-Oehler; Sibylle Oswald; Karin Eiteljörge; Ulrich Sonnenborn; Jürgen Schulze; Wolfgang Kruis; Jörg Hacker
Development of strain-specific PCR reactions for the detection of the probiotic Escherichia coli strain Nissle 1917 in fecal samples.
Research in microbiology 2003;154(1):59-66.
2003: Tobias A Oelschlaeger; Ulrich Dobrindt; Britta Janke; Barbara Middendorf; Helge Karch; Jörg Hacker
Analysis of pathogenicity islands of STEC.
Methods in molecular medicine 2003;73():99-112.
2002: Stephanie Theiss; Gerwald A Köhler; Marianne Kretschmar; Thomas Nichterlein; Jörg Hacker
New molecular methods to study gene functions in Candida infections.
Mycoses 2002;45(9-10):345-50.
2002: Ulrich Dobrindt; Gabriele Blum-Oehler; Gabor Nagy; György Schneider; Andre Johann; Gerhard Gottschalk; Jörg Hacker
Genetic structure and distribution of four pathogenicity islands (PAI I(536) to PAI IV(536)) of uropathogenic Escherichia coli strain 536.
Infection and immunity 2002;70(11):6365-72.
2002: Lubomir Grozdanov; Ulrich Zähringer; Gabriele Blum-Oehler; Lore Brade; Anke Henne; Yuriy A Knirel; Ursula Schombel; Jürgen Schulze; Ulrich Sonnenborn; Gerhard Gottschalk; Jörg Hacker; Ernst Th Rietschel; Ulrich Dobrindt
A single nucleotide exchange in the wzy gene is responsible for the semirough O6 lipopolysaccharide phenotype and serum sensitivity of Escherichia coli strain Nissle 1917.
Journal of bacteriology 2002;184(21):5912-25.
2002: Ute Hentschel; Jörn N Hopke; Matthias Horn; Anja B Friedrich; Michael Wagner; Jörg Hacker; Bradley S Moore
Molecular evidence for a uniform microbial community in sponges from different oceans.
Applied and environmental microbiology 2002;68(9):4431-40.
2002: Isabel Loessner; Katja Dietrich; Dorothea Dittrich; Jörg Hacker; Wilma Ziebuhr
Transposase-dependent formation of circular IS256 derivatives in Staphylococcus epidermidis and Staphylococcus aureus.
Journal of bacteriology 2002;184(17):4709-14.
2002: Gábor Nagy; Ulrich Dobrindt; György Schneider; A Salam Khan; Jörg Hacker; Levente Emödy
Loss of regulatory protein RfaH attenuates virulence of uropathogenic Escherichia coli.
Infection and immunity 2002;70(8):4406-13.
2002: Uri Gophna; Tobias A Oelschlaeger; Jörg Hacker; Eliora Z Ron
Role of fibronectin in curli-mediated internalization.
FEMS microbiology letters 2002;212(1):55-8.
2002: Seung-Hak Cho; Kurt Naber; Jörg Hacker; Wilma Ziebuhr
Detection of the icaADBC gene cluster and biofilm formation in Staphylococcus epidermidis isolates from catheter-related urinary tract infections.
International journal of antimicrobial agents 2002;19(6):570-5.
2002: Tobias A Oelschlaeger; Ulrich Dobrindt; Jörg Hacker
Pathogenicity islands of uropathogenic E. coli and the evolution of virulence.
International journal of antimicrobial agents 2002;19(6):517-21.
2002: Michael Steinert; Ute Hentschel; Jörg Hacker
Legionella pneumophila: an aquatic microbe goes astray.
FEMS microbiology reviews 2002;26(2):149-62.
2002: Ulrich Dobrindt; Levente Emödy; Ivaylo Gentschev; Werner Goebel; Jörg Hacker
Efficient expression of the alpha-haemolysin determinant in the uropathogenic Escherichia coli strain 536 requires the leuX-encoded tRNA(5)(Leu).
Molecular genetics and genomics : MGG 2002;267(3):370-9.
2002: Ulrich Dobrindt; Katharine Piechaczek; Angelika Schierhorn; Gunter Fischer; Michael Hecker; Jörg Hacker
Influence of the leuX-encoded tRNA5(Leu) on the regulation of gene expression in pathogenic Escherichia coli.
Journal of molecular microbiology and biotechnology 2002;4(3):205-9.
2002: Carina Skriwan; Marcela Fajardo; Sonja Hägele; Matthias Horn; Michael Wagner; Rolf Michel; Georg Krohne; Michael Schleicher; Jörg Hacker; Michael Steinert
Various bacterial pathogens and symbionts infect the amoeba Dictyostelium discoideum.
International journal of medical microbiology : IJMM 2002;291(8):615-24.
2002: Klaus Heuner; Claudia Dietrich; Carina Skriwan; Michael Steinert; Jörg Hacker
Influence of the alternative sigma(28) factor on virulence and flagellum expression of Legionella pneumophila.
Infection and immunity 2002;70(3):1604-8.
2002: Stephanie Theiss; Marianne Kretschmar; Thomas Nichterlein; Holger Hof; Nina Agabian; Jörg Hacker; Gerwald A Köhler
Functional analysis of a vacuolar ABC transporter in wild-type Candida albicans reveals its involvement in virulence.
Molecular microbiology 2002;43(3):571-84.
2002: Ulrich Dobrindt; Ute Hentschel; James B Kaper; Jörg Hacker
Genome plasticity in pathogenic and nonpathogenic enterobacteria.
Current topics in microbiology and immunology 2002;264(1):157-75.
2002: Klaus Heuner; Michael Steinert; R Marre; Jörg Hacker
Genomic structure and evolution of Legionella species.
Current topics in microbiology and immunology 2002;264(2):61-78.
2002: G Köhler; J Morschhäuser; Jörg Hacker
Genome structure of pathogenic fungi.
Current topics in microbiology and immunology 2002;264(2):149-66.
2002: Tobias A Oelschlaeger; Ulrich Dobrindt; Jörg Hacker
Virulence factors of uropathogens.
Current opinion in urology 2002;12(1):33-8.
2001: Herbert Schmidt; Wen-Lan Zhang; U Hemmrich; Sandra Jelacic; Werner Brunder; Phillip I Tarr; Ulrich Dobrindt; Jörg Hacker; Helge Karch
Identification and characterization of a novel genomic island integrated at selC in locus of enterocyte effacement-negative, Shiga toxin-producing Escherichia coli.
Infection and immunity 2001;69(11):6863-73.
2001: Alan Riboldi-Tunnicliffe; Bettina König; S Jessen; Manfred S Weiss; Jens-Ulrich Rahfeld; Jörg Hacker; G Fischer; Rolf Hilgenfeld
Crystal structure of Mip, a prolylisomerase from Legionella pneumophila.
Nature structural biology 2001;8(9):779-83.
2001: Ulrich Dobrindt; Jörg Hacker
Regulation of tRNA5Leu-encoding gene leuX that is associated with a pathogenicity island in the uropathogenic Escherichia coli strain 536.
Molecular genetics and genomics : MGG 2001;265(5):895-904.
2001: Werner Brunder; A Salam Khan; Jörg Hacker; Helge Karch
Novel type of fimbriae encoded by the large plasmid of sorbitol-fermenting enterohemorrhagic Escherichia coli O157:H(-).
Infection and immunity 2001;69(7):4447-57.
2001: Ulrich Dobrindt; Gabriele Blum-Oehler; Thomas Hartsch; Gerhard Gottschalk; Eliora Z Ron; R Fünfstück; Jörg Hacker
S-Fimbria-encoding determinant sfa(I) is located on pathogenicity island III(536) of uropathogenic Escherichia coli strain 536.
Infection and immunity 2001;69(7):4248-56.
2001: Ute Hentschel; Jörg Hacker
Pathogenicity islands: the tip of the iceberg.
Microbes and infection / Institut Pasteur 2001;3(7):545-8.
2001: Britta Janke; Ulrich Dobrindt; Jörg Hacker; Gabriele Blum-Oehler
A subtractive hybridisation analysis of genomic differences between the uropathogenic E. coli strain 536 and the E. coli K-12 strain MG1655.
FEMS microbiology letters 2001;199(1):61-6.
2001: Jörg Hacker; Elisabeth Carniel
Ecological fitness, genomic islands and bacterial pathogenicity. A Darwinian view of the evolution of microbes.
EMBO reports 2001;2(5):376-81.
2001: D Grimm; W F Ludwig; B C Brandt; Rolf Michel; K H Schleifer; Jörg Hacker; Michael Steinert
Development of 18S rRNA-targeted oligonucleotide probes for specific detection of Hartmannella and Naegleria in Legionella-positive environmental samples.
Systematic and applied microbiology 2001;24(1):76-82.
2001: Uri Gophna; M Barlev; R Seijffers; T A Oelschlager; Jörg Hacker; Eliora Z Ron
Curli fibers mediate internalization of Escherichia coli by eukaryotic cells.
Infection and immunity 2001;69(4):2659-65.
2001: Claudia Dietrich; Klaus Heuner; BC Brand; Jörg Hacker; Michael Steinert
Flagellum of Legionella pneumophila positively affects the early phase of infection of eukaryotic host cells.
Infection and immunity 2001;69(4):2116-22.
2001: Uri Gophna; Tobias A Oelschlaeger; Jörg Hacker; Eliora Z Ron
Yersinia HPI in septicemic Escherichia coli strains isolated from diverse hosts.
FEMS microbiology letters 2001;196(1):57-60.
2001: G Nagy; Ulrich Dobrindt; M Kupfer; Levente Emödy; Helge Karch; Jörg Hacker
Expression of hemin receptor molecule ChuA is influenced by RfaH in uropathogenic Escherichia coli strain 536.
Infection and immunity 2001;69(3):1924-8.
2001: Barbara Middendorf; Gabriele Blum-Oehler; Ulrich Dobrindt; I Mühldorfer; S Salge; Jörg Hacker
The pathogenicity islands (PAIs) of the uropathogenic Escherichia coli strain 536: island probing of PAI II536.
The Journal of infectious diseases 2001;183 Suppl 1():S17-20.
2001: Michael Steinert; Klaus Heuner; Jörg Hacker
Legionellosis, a disease transmitted by technical vectors.
Contributions to microbiology 2001;8():12-9.
2001: Wilma Ziebuhr; I Loessner; V Krimmer; Jörg Hacker
Methods to detect and analyze phenotypic variation in biofilm-forming Staphylococci.
Methods in enzymology 2001;336():195-205.
2000: S Gertz; Susanne Engelmann; Roland Schmid; Anne-Kathrin Ziebandt; K Tischer; Christian Scharf; Jörg Hacker; Michael Hecker
Characterization of the sigma(B) regulon in Staphylococcus aureus.
Journal of bacteriology 2000;182(24):6983-91.
2000: Shwan Rachid; Knut Ohlsen; Wolfgang Witte; Jörg Hacker; Wilma Ziebuhr
Effect of subinhibitory antibiotic concentrations on polysaccharide intercellular adhesin expression in biofilm-forming Staphylococcus epidermidis.
Antimicrobial agents and chemotherapy 2000;44(12):3357-63.
2000: Shwan Rachid; Knut Ohlsen; Ursula Wallner; Jörg Hacker; Michael Hecker; Wilma Ziebuhr
Alternative transcription factor sigma(B) is involved in regulation of biofilm expression in a Staphylococcus aureus mucosal isolate.
Journal of bacteriology 2000;182(23):6824-6.
2000: S Riedl; Knut Ohlsen; G Werner; Wolfgang Witte; Jörg Hacker
Impact of flavophospholipol and vancomycin on conjugational transfer of vancomycin resistance plasmids.
Antimicrobial agents and chemotherapy 2000;44(11):3189-92.
2000: Ulrich Dobrindt; Britta Janke; Katharine Piechaczek; G Nagy; Wilma Ziebuhr; Gunter Fischer; Angelika Schierhorn; Michael Hecker; Gabriele Blum-Oehler; Jörg Hacker
Toxin genes on pathogenicity islands: impact for microbial evolution.
International journal of medical microbiology : IJMM 2000;290(4-5):307-11.
2000: Udo Lorenz; Knut Ohlsen; Helge Karch; M Hecker; Arnulf Thiede; Jörg Hacker
Human antibody response during sepsis against targets expressed by methicillin resistant Staphylococcus aureus.
FEMS immunology and medical microbiology 2000;29(2):145-53.
2000: Reuven Babai; B E Stern; Jörg Hacker; Eliora Z Ron
New fimbrial gene cluster of S-fimbrial adhesin family.
Infection and immunity 2000;68(10):5901-7.
2000: Klaus Heuner; Claudia Dietrich; Michael Steinert; Ulf B Göbel; Jörg Hacker
Cloning and characterization of a Legionella pneumophila-specific gene encoding a member of the LysR family of transcriptional regulators.
Molecular & general genetics : MGG 2000;264(1-2):204-11.
2000: A Salam Khan; B Kniep; Tobias A Oelschlaeger; I Van Die; T Korhonen; Jörg Hacker
Receptor structure for F1C fimbriae of uropathogenic Escherichia coli.
Infection and immunity 2000;68(6):3541-7.
2000: Joachim Morschhäuser; G Köhler; Wilma Ziebuhr; Gabriele Blum-Oehler; Ulrich Dobrindt; Jörg Hacker
Evolution of microbial pathogens.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2000;355(1397):695-704.
2000: Ute Hentschel; Michael Steinert; Jörg Hacker
Common molecular mechanisms of symbiosis and pathogenesis.
Trends in microbiology 2000;8(5):226-31.
2000: Sonja Hägele; Rolf Köhler; H Merkert; Michael Schleicher; Jörg Hacker; Michael Steinert
Dictyostelium discoideum: a new host model system for intracellular pathogens of the genus Legionella.
Cellular microbiology 2000;2(2):165-71.
2000: Katharine Piechaczek; Ulrich Dobrindt; Angelika Schierhorn; G S Fischer; Michael Hecker; Jörg Hacker
Influence of pathogenicity islands and the minor leuX-encoded tRNA5Leu on the proteome pattern of the uropathogenic Escherichia coli strain 536.
International journal of medical microbiology : IJMM 2000;290(1):75-84.
2000: A Salam Khan; I Mühldorfer; V Demuth; Ursula Wallner; Timo K Korhonen; Jörg Hacker
Functional analysis of the minor subunits of S fimbrial adhesion (SfaI) in pathogenic Escherichia coli.
Molecular & general genetics : MGG 2000;263(1):96-105.
2000: Udo Lorenz; Knut Ohlsen; Helge Karch; Arnulf Thiede; Jörg Hacker
Immunodominant proteins in human sepsis caused by methicillin resistant Staphylococcus aureus.
Advances in experimental medicine and biology 2000;485():273-8.
2000: A Salam Khan; Jörg Hacker
Glycolipid receptors of F1C fimbrial adhesin of uropathogenic Escherichia coli.
Advances in experimental medicine and biology 2000;485():213-7.
2000: Shwan Rachid; S Cho; Knut Ohlsen; Jörg Hacker; Wilma Ziebuhr
Induction of Staphylococcus epidermidis biofilm formation by environmental factors: the possible involvement of the alternative transcription factor sigB.
Advances in experimental medicine and biology 2000;485():159-66.
2000: Wilma Ziebuhr; I Lössner; Shwan Rachid; Katja Dietrich; F Götz; Jörg Hacker
Modulation of the polysaccharide intercellular adhesin (PIA) expression in biofilm forming Staphylococcus epidermidis. Analysis of genetic mechanisms.
Advances in experimental medicine and biology 2000;485():151-7.
2000: R Pouttu; T Puustinen; Maini Kukkonen; Ritva Virkola; Minni R L Laurila; Jörg Hacker; P Klemm; Timo K Korhonen
Functional variability of type 1 fimbriae of Escherichia coli.
Advances in experimental medicine and biology 2000;485():63-8.
2000: G Nagy; Ulrich Dobrindt; Gabriele Blum-Oehler; L Emódy; Werner Goebel; Jörg Hacker
Analysis of the hemolysin determinants of the uropathogenic Escherichia coli strain 536.
Advances in experimental medicine and biology 2000;485():57-61.
2000: Britta Janke; Jörg Hacker; Gabriele Blum-Oehler
Genetic characterization of the uropathogenic E. coli strain 536--a subtractive hybridization analysis.
Advances in experimental medicine and biology 2000;485():53-6.
2000: Gabriele Blum-Oehler; Ulrich Dobrindt; Britta Janke; G Nagy; Katharine Piechaczek; Jörg Hacker
Pathogenicity islands of uropathogenic E. coli and evolution of virulence.
Advances in experimental medicine and biology 2000;485():25-32.
2000: Jörg Hacker
Urinary tract infection: from basic science to clinical application.
Advances in experimental medicine and biology 2000;485():1-8.
2000: Jörg Hacker; James B Kaper
Pathogenicity islands and the evolution of microbes.
Annual review of microbiology 2000;54():641-79.
2000: B C Brand; R I Amann; Michael Steinert; D Grimm; Jörg Hacker
Identification and in situ detection of intracellular bacteria in the environment.
Sub-cellular biochemistry 2000;33():601-24.
2000: Tobias A Oelschlaeger; Jörg Hacker
Strategies of bacterial interaction with eukaryotic cells.
Sub-cellular biochemistry 2000;33():xxix-xxxviii.
2000: Michael Steinert; Ute Hentschel; Jörg Hacker
Symbiosis and pathogenesis: evolution of the microbe-host interaction.
Die Naturwissenschaften 2000;87(1):1-11.
2000: Rolf Köhler; A Bubert; Werner Goebel; Michael Steinert; Jörg Hacker; B Bubert
Expression and use of the green fluorescent protein as a reporter system in Legionella pneumophila.
Molecular & general genetics : MGG 2000;262(6):1060-9.
1999: Wilma Ziebuhr; Knut Ohlsen; Helge Karch; T Korhonen; Jörg Hacker
Evolution of bacterial pathogenesis.
Cellular and molecular life sciences : CMLS 1999;56(9-10):719-28.
1999: V Krimmer; H Merkert; Christof von Eiff; Matthias Frosch; Jochen Eulert; Jochen F Löhr; Jörg Hacker; Wilma Ziebuhr
Detection of Staphylococcus aureus and Staphylococcus epidermidis in clinical samples by 16S rRNA-directed in situ hybridization.
Journal of clinical microbiology 1999;37(8):2667-73.
1999: S Fuchs; I Mühldorfer; Arthur Donohue-Rolfe; Monika Kerényi; Levente Emödy; R Alexiev; P Nenkov; Jörg Hacker
Influence of RecA on in vivo virulence and Shiga toxin 2 production in Escherichia coli pathogens.
Microbial pathogenesis 1999;27(1):13-23.
1999: Klaus Heuner; BC Brand; Jörg Hacker
The expression of the flagellum of Legionella pneumophila is modulated by different environmental factors.
FEMS microbiology letters 1999;175(1):69-77.
1999: Peter Staib; Marianne Kretschmar; Thomas Nichterlein; Gerwald A Köhler; Sonja Michel; Holger Hof; Jörg Hacker; Joachim Morschhäuser
Host-induced, stage-specific virulence gene activation in Candida albicans during infection.
Molecular microbiology 1999;32(3):533-46.
1999: AM Sarén; Ritva Virkola; Jörg Hacker; Timo K Korhonen
The cellular form of human fibronectin as an adhesion target for the S fimbriae of meningitis-associated Escherichia coli.
Infection and immunity 1999;67(5):2671-6.
1999: Joachim Morschhäuser; M Ruhnke; S Michel; Jörg Hacker
Identification of CARE-2-negative Candida albicans isolates as Candida dubliniensis.
Mycoses 1999;42(1-2):29-32.
1999: S Gertz; Susanne Engelmann; Roland Schmid; Knut Ohlsen; Jörg Hacker; Michael Hecker
Regulation of sigmaB-dependent transcription of sigB and asp23 in two different Staphylococcus aureus strains.
Molecular & general genetics : MGG 1999;261(3):558-66.
1999: Wilma Ziebuhr; V Krimmer; Shwan Rachid; I Lössner; F Götz; Jörg Hacker
A novel mechanism of phase variation of virulence in Staphylococcus epidermidis: evidence for control of the polysaccharide intercellular adhesin synthesis by alternating insertion and excision of the insertion sequence element IS256.
Molecular microbiology 1999;32(2):345-56.
1999: R Pouttu; T Puustinen; Ritva Virkola; Jörg Hacker; P Klemm; Timo K Korhonen
Amino acid residue Ala-62 in the FimH fimbrial adhesin is critical for the adhesiveness of meningitis-associated Escherichia coli to collagens.
Molecular microbiology 1999;31(6):1747-57.
1999: Frank-Michael C Müller; A Lischewski; Dag Harmsen; Jörg Hacker
Standardized molecular typing.
Mycoses 1999;42 Suppl 2():69-72.
1999: Frank-Michael C Müller; Joachim Morschhäuser; Gerwald A Köhler; Tobias A Oelschlaeger; Wilma Ziebuhr; Jörg Hacker
[Adherence and invasion-two pathogenicity factors in bacterial and fungal pathogens].
Mycoses 1999;42 Suppl 1():39-42.
1999: A Lischewski; Dag Harmsen; K Wilms; G Baier; U Gunzer; Hartwig Klinker; Martin Wilhelm; A Schwinn; Jörg Hacker
Molecular epidemiology of Candida albicans isolates from AIDS and cancer patients using a novel standardized CARE-2 DNA fingerprinting technique.
Mycoses 1999;42(5-6):371-83.
1998: Sonja Hägele; Jörg Hacker; BC Brand
Legionella pneumophila kills human phagocytes but not protozoan host cells by inducing apoptotic cell death.
FEMS microbiology letters 1998;169(1):51-8.
1998: Michael Steinert; G Ockert; C Lück; Jörg Hacker
Regrowth of Legionella pneumophila in a heat-disinfected plumbing system.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1998;288(3):331-42.
1998: Knut Ohlsen; Wilma Ziebuhr; K P Koller; W Hell; Thomas A Wichelhaus; Jörg Hacker
Effects of subinhibitory concentrations of antibiotics on alpha-toxin (hla) gene expression of methicillin-sensitive and methicillin-resistant Staphylococcus aureus isolates.
Antimicrobial agents and chemotherapy 1998;42(11):2817-23.
1998: D Grimm; H Merkert; W Ludwig; K H Schleifer; Jörg Hacker; B C Brand
Specific detection of Legionella pneumophila: construction of a new 16S rRNA-targeted oligonucleotide probe.
Applied and environmental microbiology 1998;64(7):2686-90.
1998: Ulrich Dobrindt; Paul S Cohen; M Utley; I Mühldorfer; Jörg Hacker
The leuX-encoded tRNA5(Leu) but not the pathogenicity islands I and II influence the survival of the uropathogenic Escherichia coli strain 536 in CD-1 mouse bladder mucus in the stationary phase.
FEMS microbiology letters 1998;162(1):135-41.
1998: Florian Gunzer; U Bohn; S Fuchs; I Mühldorfer; Jörg Hacker; Saul Tzipori; Arthur Donohue-Rolfe
Construction and characterization of an isogenic slt-ii deletion mutant of enterohemorrhagic Escherichia coli.
Infection and immunity 1998;66(5):2337-41.
1998: Joachim Morschhäuser; S Michel; Jörg Hacker
Expression of a chromosomally integrated, single-copy GFP gene in Candida albicans, and its use as a reporter of gene regulation.
Molecular & general genetics : MGG 1998;257(4):412-20.
1997: A Lischewski; Dag Harmsen; Jörg Hacker; Joachim Morschhäuser
Standardized molecular typing of Candida albicans strains.
Mycoses 1997;40(9-10):369-72.
1997: Benita Westerlund-Wikström; Jarna Tanskanen; Ritva Virkola; Jörg Hacker; M Lindberg; Mikael Skurnik; Timo K Korhonen
Functional expression of adhesive peptides as fusions to Escherichia coli flagellin.
Protein engineering 1997;10(11):1319-26.
1997: A Lischewski; Marianne Kretschmar; H Hof; R Amann; Jörg Hacker; Joachim Morschhäuser
Detection and identification of Candida species in experimentally infected tissue and human blood by rRNA-specific fluorescent in situ hybridization.
Journal of clinical microbiology 1997;35(11):2943-8.
1997: A Ritter; David L Gally; P B Olsen; Ulrich Dobrindt; A Friedrich; P Klemm; Jörg Hacker
The Pai-associated leuX specific tRNA5(Leu) affects type 1 fimbriation in pathogenic Escherichia coli by control of FimB recombinase expression.
Molecular microbiology 1997;25(5):871-82.
1997: Knut Ohlsen; K P Koller; Jörg Hacker
Analysis of expression of the alpha-toxin gene (hla) of Staphylococcus aureus by using a chromosomally encoded hla::lacZ gene fusion.
Infection and immunity 1997;65(9):3606-14.
1997: Joachim Morschhäuser; Ritva Virkola; Timo K Korhonen; Jörg Hacker
Degradation of human subendothelial extracellular matrix by proteinase-secreting Candida albicans.
FEMS microbiology letters 1997;153(2):349-55.
1997: Michael Steinert; Levente Emödy; R Amann; Jörg Hacker
Resuscitation of viable but nonculturable Legionella pneumophila Philadelphia JR32 by Acanthamoeba castellanii.
Applied and environmental microbiology 1997;63(5):2047-53.
1997: Reuven Babai; Gabriele Blum-Oehler; B E Stern; Jörg Hacker; Eliora Z Ron
Virulence patterns from septicemic Escherichia coli O78 strains.
FEMS microbiology letters 1997;149(1):99-105.
1997: Jörg Hacker; Gabriele Blum-Oehler; I Mühldorfer; H Tschäpe
Pathogenicity islands of virulent bacteria: structure, function and impact on microbial evolution.
Molecular microbiology 1997;23(6):1089-97.
1997: Wilma Ziebuhr; C Heilmann; F Götz; P Meyer; K Wilms; E Straube; Jörg Hacker
Detection of the intercellular adhesion gene cluster (ica) and phase variation in Staphylococcus epidermidis blood culture strains and mucosal isolates.
Infection and immunity 1997;65(3):890-6.
1997: Gabriele Blum-Oehler; J Heesemann; D Kranzfelder; F Scheutz; Jörg Hacker
Characterization of Escherichia coli serotype O12:K1:H7 isolates from an immunocompetent carrier with a history of spontaneous abortion and septicemia.
European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology 1997;16(2):153-5.
1997: Klaus Heuner; Jörg Hacker; BC Brand
The alternative sigma factor sigma28 of Legionella pneumophila restores flagellation and motility to an Escherichia coli fliA mutant.
Journal of bacteriology 1997;179(1):17-23.
1996: B Jain; BC Brand; Paul Christian Lück; M Di Berardino; Peter Dimroth; Jörg Hacker
An oxaloacetate decarboxylase homologue protein influences the intracellular survival of Legionella pneumophila.
FEMS microbiology letters 1996;145(2):273-9.
1996: A Müller; Jörg Hacker; BC Brand
Evidence for apoptosis of human macrophage-like HL-60 cells by Legionella pneumophila infection.
Infection and immunity 1996;64(12):4900-6.
1996: I Mühldorfer; G Blum; Arthur Donohue-Rolfe; H Heier; T Olschläger; Helmut Tschäpe; U Wallner; Jörg Hacker
Characterization of Escherichia coli strains isolated from environmental water habitats and from stool samples of healthy volunteers.
Research in microbiology 1996;147(8):625-35.
1996: A Lischewski; R I Amann; Dag Harmsen; H Merkert; Jörg Hacker; Joachim Morschhäuser
Specific detection of Candida albicans and Candida tropicalis by fluorescent in situ hybridization with an 18S rRNA-targeted oligonucleotide probe.
Microbiology (Reading, England) 1996;142 ( Pt 10)():2731-40.
1996: G Blum; I Mühldorfer; Peter Kuhnert; Joachim Frey; Jörg Hacker
Comparative methodology to investigate the presence of Escherichia coli K-12 strains in environmental and human stool samples.
FEMS microbiology letters 1996;143(1):77-82.
1996: I Mühldorfer; Jörg Hacker; Gerald T Keusch; David W K Acheson; Helmut Tschäpe; Anne Kane; A Ritter; T Olschläger; Arthur Donohue-Rolfe
Regulation of the Shiga-like toxin II operon in Escherichia coli.
Infection and immunity 1996;64(2):495-502.
1996: T A Oelschlaeger; Joachim Morschhäuser; C Meier; C Schipper; Jörg Hacker
Adhesion and invasion of Escherichia coli. Studies on function and regulation.
Advances in experimental medicine and biology 1996;408():57-62.
1996: Joachim Morschhäuser; Gerwald A Köhler; Jörg Hacker
[Are there pathogenicity factors in fungi?].
Mycoses 1996;39 Suppl 1():51-4.
1995: E Wintermeyer; B Ludwig; Michael Steinert; B Schmidt; G Fischer; Jörg Hacker
Influence of site specifically altered Mip proteins on intracellular survival of Legionella pneumophila in eukaryotic cells.
Infection and immunity 1995;63(12):4576-83.
1995: L Bender-Beck; W Mühlenberg; Paul Christian Lück; M Ott; I Horbach; F J Fehrenbach; G Wewalka; Jörg Hacker
[Genomic DNA fingerprints of Legionella pneumophila serogroup 2 strains as an epidemiologic marker].
Immunität und Infektion 1995;23(4):137-9.
1995: G Blum; R Marre; Jörg Hacker
Properties of Escherichia coli strains of serotype O6.
Infection 1995;23(4):234-6.
1995: Klaus Heuner; L Bender-Beck; BC Brand; Paul Christian Lück; K H Mann; R Marre; M Ott; Jörg Hacker
Cloning and genetic characterization of the flagellum subunit gene (flaA) of Legionella pneumophila serogroup 1.
Infection and immunity 1995;63(7):2499-507.
1995: A Ritter; G Blum; L Emödy; Monika Kerényi; A Böck; B Neuhierl; W Rabsch; F Scheutz; Jörg Hacker
tRNA genes and pathogenicity islands: influence on virulence and metabolic properties of uropathogenic Escherichia coli.
Molecular microbiology 1995;17(1):109-21.
1995: Michael Steinert; H Engelhard; M Flügel; E Wintermeyer; Jörg Hacker
The Lly protein protects Legionella pneumophila from light but does not directly influence its intracellular survival in Hartmannella vermiformis.
Applied and environmental microbiology 1995;61(6):2428-30.
1995: A Lischewski; M Ruhnke; I Tennagen; G Schönian; Joachim Morschhäuser; Jörg Hacker
Molecular epidemiology of Candida isolates from AIDS patients showing different fluconazole resistance profiles.
Journal of clinical microbiology 1995;33(3):769-71.
1995: G Blum; V Falbo; Alfredo Caprioli; Jörg Hacker
Gene clusters encoding the cytotoxic necrotizing factor type 1, Prs-fimbriae and alpha-hemolysin form the pathogenicity island II of the uropathogenic Escherichia coli strain J96.
FEMS microbiology letters 1995;126(2):189-95.
1995: V Vetter; Jörg Hacker
Strategies for employing molecular genetics to study tip adhesions.
Methods in enzymology 1995;253():229-41.
1994: B Ludwig; J Rahfeld; B Schmidt; K Mann; E Wintermeyer; G Fischer; Jörg Hacker
Characterization of Mip proteins of Legionella pneumophila.
FEMS microbiology letters 1994;118(1-2):23-30.
1994: E Wintermeyer; M Flügel; M Ott; Michael Steinert; U Rdest; K H Mann; Jörg Hacker
Sequence determination and mutational analysis of the lly locus of Legionella pneumophila.
Infection and immunity 1994;62(3):1109-17.
1994: I Mühldorfer; Jörg Hacker
Genetic aspects of Escherichia coli virulence.
Microbial pathogenesis 1994;16(3):171-81.
1994: J Morschhäuser; V Vetter; L Emödy; Jörg Hacker
Adhesin regulatory genes within large, unstable DNA regions of pathogenic Escherichia coli: cross-talk between different adhesin gene clusters.
Molecular microbiology 1994;11(3):555-66.
1994: G Blum; M Ott; A Lischewski; A Ritter; H Imrich; Helmut Tschäpe; Jörg Hacker
Excision of large DNA regions termed pathogenicity islands from tRNA-specific loci in the chromosome of an Escherichia coli wild-type pathogen.
Infection and immunity 1994;62(2):606-14.
1993: Jörg Hacker; G Fischer
Immunophilins: structure-function relationship and possible role in microbial pathogenicity.
Molecular microbiology 1993;10(3):445-56.
1993: Ritva Virkola; J Parkkinen; Jörg Hacker; Timo K Korhonen
Sialyloligosaccharide chains of laminin as an extracellular matrix target for S fimbriae of Escherichia coli.
Infection and immunity 1993;61(10):4480-4.
1993: R Ahrens; M Ott; A Ritter; H Hoschützky; T Bühler; F Lottspeich; G J Boulnois; K Jann; Jörg Hacker
Genetic analysis of the gene cluster encoding nonfimbrial adhesin I from an Escherichia coli uropathogen.
Infection and immunity 1993;61(6):2505-12.
1993: Helmut Tschäpe; R Prager; L Bender; M Ott; G Blum; Jörg Hacker
Dissection of pathogenetic determinants and their genomic positions for the evaluation of epidemic strains and infection routes.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1993;278(2-3):425-35.
1993: Jörg Hacker; M Ott; E Wintermeyer; B Ludwig; G Fischer
Analysis of virulence factors of Legionella pneumophila.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1993;278(2-3):348-58.
1993: J Morschhäuser; V Vetter; T Korhonen; B E Uhlin; Jörg Hacker
Regulation and binding properties of S fimbriae cloned from E. coli strains causing urinary tract infection and meningitis.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1993;278(2-3):165-76.
1993: J Morschhäuser; B E Uhlin; Jörg Hacker
Transcriptional analysis and regulation of the sfa determinant coding for S fimbriae of pathogenic Escherichia coli strains.
Molecular & general genetics : MGG 1993;238(1-2):97-105.
1993: Jörg Hacker; H Kestler; H Hoschützky; K Jann; F Lottspeich; Timo K Korhonen
Cloning and characterization of the S fimbrial adhesin II complex of an Escherichia coli O18:K1 meningitis isolate.
Infection and immunity 1993;61(2):544-50.
1992: M Ott; L Bender; Paul Christian Lück; P Meyer; Jörg Hacker
Distribution of legionellae in a hospital water system: prevalence of immunologically and genetically related Legionella pneumophila serogroup 6 isolates.
FEMS microbiology letters 1992;74(2-3):201-5.
1992: F Linhardt; Wilma Ziebuhr; P Meyer; Wolfgang Witte; Jörg Hacker
Pulsed-field gel electrophoresis of genomic restriction fragments as a tool for the epidemiological analysis of Staphylococcus aureus and coagulase-negative staphylococci.
FEMS microbiology letters 1992;74(2-3):181-5.
1992: Jörg Hacker
Role of fimbrial adhesins in the pathogenesis of Escherichia coli infections.
Canadian journal of microbiology 1992;38(7):720-7.
1992: Jörg Hacker; U Wallner; E Straube; H Hof
[Effect of antibiotics on expression of virulence-associated genes].
Zeitschrift für ärztliche Fortbildung 1992;86(6):271-6.
1992: T Meyer; Helge Karch; Jörg Hacker; H Bocklage; Jürgen Heesemann
Cloning and sequencing of a Shiga-like toxin II-related gene from Escherichia coli O157:H7 strain 7279.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1992;276(2):176-88.
1992: Jörg Hacker; M Ott; G Blum; R Marre; Jürgen Heesemann; Helmut Tschäpe; Werner Goebel
Genetics of Escherichia coli uropathogenicity: analysis of the O6:K15:H31 isolate 536.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1992;276(2):165-75.
1992: Helmut Tschäpe; L Bender; M Ott; W Wittig; Jörg Hacker
Restriction fragment length polymorphism and virulence pattern of the veterinary pathogen Escherichia coli O139:K82:H1.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1992;276(2):264-72.
1991: M Ott; L Bender; E Chirinos; W Ehret; Jörg Hacker
Phenotype versus genotype of the 19 kD peptido-glycan associated protein of Legionella (PpIA), among Legionellae and other gram-negative bacteria.
Microbial pathogenesis 1991;11(5):357-65.
1991: Paul Christian Lück; L Bender; M Ott; Jürgen Herbert Helbig; Jörg Hacker
Analysis of Legionella pneumophila serogroup 6 strains isolated from a hospital warm water supply over a three-year period by using genomic long-range mapping techniques and monoclonal antibodies.
Applied and environmental microbiology 1991;57(11):3226-31.
1991: L Bender; M Ott; A Debes; U Rdest; Jürgen Heesemann; Jörg Hacker
Distribution, expression, and long-range mapping of legiolysin gene (lly)-specific DNA sequences in legionellae.
Infection and immunity 1991;59(9):3333-6.
1991: M Ott; P Messner; Jürgen Heesemann; R Marre; Jörg Hacker
Temperature-dependent expression of flagella in Legionella.
Journal of general microbiology 1991;137(8):1955-61.
1991: B Ludwig; A Schmid; R Marre; Jörg Hacker
Cloning, genetic analysis, and nucleotide sequence of a determinant coding for a 19-kilodalton peptidoglycan-associated protein (Ppl) of Legionella pneumophila.
Infection and immunity 1991;59(8):2515-21.
1991: M Ott; L Bender; G Blum; M Schmittroth; Mark Achtman; Helmut Tschäpe; Jörg Hacker
Virulence patterns and long-range genetic mapping of extraintestinal Escherichia coli K1, K5, and K100 isolates: use of pulsed-field gel electrophoresis.
Infection and immunity 1991;59(8):2664-72.
1991: I van Die; C Kramer; Jörg Hacker; H Bergmans; W Jongen; W Hoekstra
Nucleotide sequence of the genes coding for minor fimbrial subunits of the F1C fimbriae of Escherichia coli.
Research in microbiology 1991;142(6):653-8.
1991: J Parkkinen; Jörg Hacker; Timo K Korhonen
Enhancement of tissue plasminogen activator-catalyzed plasminogen activation by Escherichia coli S fimbriae associated with neonatal septicaemia and meningitis.
Thrombosis and haemostasis 1991;65(5):483-6.
1991: E Wintermeyer; U Rdest; B Ludwig; A Debes; Jörg Hacker
Characterization of legiolysin (lly), responsible for haemolytic activity, colour production and fluorescence of Legionella pneumophila.
Molecular microbiology 1991;5(5):1135-43.
1991: M Ott; Jörg Hacker
Analysis of the variability of S-fimbriae expression in an Escherichia coli pathogen.
FEMS microbiology letters 1991;63(2-3):233-8.
1991: M Ott; L Bender; R Marre; Jörg Hacker
Pulsed field electrophoresis of genomic restriction fragments for the detection of nosocomial Legionella pneumophila in hospital water supplies.
Journal of clinical microbiology 1991;29(4):813-5.
1991: G Blum; M Ott; Alan S Cross; Jörg Hacker
Virulence determinants of Escherichia coli O6 extraintestinal isolates analysed by Southern hybridizations and DNA long range mapping techniques.
Microbial pathogenesis 1991;10(2):127-36.
1991: Jörg Hacker; M Ott; B Ludwig; U Rdest
Intracellular survival and expression of virulence determinants of Legionella pneumophila.
Infection 1991;19 Suppl 4():S198-201.
1991: U Rdest; E Wintermeyer; B Ludwig; Jörg Hacker
Legiolysin, a new hemolysin from L. pneumophila.
Zentralblatt für Bakteriologie : international journal of medical microbiology 1991;274(4):471-4.
1990: L Bender; M Ott; R Marre; Jörg Hacker
Genome analysis of Legionella ssp. by orthogonal field alternation gel electrophoresis (OFAGE).
FEMS microbiology letters 1990;60(3):253-7.
1990: T Schmoll; Joachim Morschhäuser; M Ott; B Ludwig; I van Die; Jörg Hacker
Complete genetic organization and functional aspects of the Escherichia coli S fimbrial adhesion determinant: nucleotide sequence of the genes sfa B, C, D, E, F.
Microbial pathogenesis 1990;9(5):331-43.
1990: T Schmoll; M Ott; B Oudega; Jörg Hacker
Use of a wild-type gene fusion to determine the influence of environmental conditions on expression of the S fimbrial adhesin in an Escherichia coli pathogen.
Journal of bacteriology 1990;172(9):5103-11.
1990: Joachim Morschhäuser; H Hoschützky; K Jann; Jörg Hacker
Functional analysis of the sialic acid-binding adhesin SfaS of pathogenic Escherichia coli by site-specific mutagenesis.
Infection and immunity 1990;58(7):2133-8.
1990: Jörg Hacker; L Bender; M Ott; J Wingender; B Lund; R Marre; Werner Goebel
Deletions of chromosomal regions coding for fimbriae and hemolysins occur in vitro and in vivo in various extraintestinal Escherichia coli isolates.
Microbial pathogenesis 1990;8(3):213-25.
1990: N Riegman; R Kusters; H Van Veggel; H Bergmans; Paul M P van Bergen en Henegouwen; Jörg Hacker; I Van Die
F1C fimbriae of a uropathogenic Escherichia coli strain: genetic and functional organization of the foc gene cluster and identification of minor subunits.
Journal of bacteriology 1990;172(2):1114-20.
1990: Jörg Hacker
Genetic determinants coding for fimbriae and adhesins of extraintestinal Escherichia coli.
Current topics in microbiology and immunology 1990;151():1-27.
1989: T Schmoll; H Hoschützky; Joachim Morschhäuser; F Lottspeich; K Jann; Jörg Hacker
Analysis of genes coding for the sialic acid-binding adhesin and two other minor fimbrial subunits of the S-fimbrial adhesin determinant of Escherichia coli.
Molecular microbiology 1989;3(12):1735-44.
1989: Jörg Hacker; M Ott
[Genetic regulatory mechanisms of bacterial virulence].
Immunität und Infektion 1989;17(6):199-205.
1988: M Ott; H Hoschützky; K Jann; I Van Die; Jörg Hacker
Gene clusters for S fimbrial adhesin (sfa) and F1C fimbriae (foc) of Escherichia coli: comparative aspects of structure and function.
Journal of bacteriology 1988;170(9):3983-90.
1988: J Parkkinen; Timo K Korhonen; AK Pere; Jörg Hacker; S Soinila
Binding sites in the rat brain for Escherichia coli S fimbriae associated with neonatal meningitis.
The Journal of clinical investigation 1988;81(3):860-5.
1987: Trinad Chakraborty; S Kathariou; Jörg Hacker; H Hof; B Huhle; W Wagner; Michael Kuhn; Werner Goebel
Molecular analysis of bacterial cytolysins.
Reviews of infectious diseases 1987;9 Suppl 5():S456-66.
1987: M Ott; T Schmoll; W Goebel; I Van Die; Jörg Hacker
Comparison of the genetic determinant coding for the S-fimbrial adhesin (sfa) of Escherichia coli to other chromosomally encoded fimbrial determinants.
Infection and immunity 1987;55(8):1940-3.
1987: C Hughes; Jörg Hacker; H Düvel; Werner Goebel
Chromosomal deletions and rearrangements cause coordinate loss of haemolysis, fimbriation and serum resistance in a uropathogenic strain of Escherichia coli.
Microbial pathogenesis 1987;2(3):227-30.
1986: Jörg Hacker; H Hof; Levente Emödy; Werner Goebel
Influence of cloned Escherichia coli hemolysin genes, S-fimbriae and serum resistance on pathogenicity in different animal models.
Microbial pathogenesis 1986;1(6):533-47.
1986: M Ott; Jörg Hacker; T Schmoll; T Jarchau; T K Korhonen; W Goebel
Analysis of the genetic determinants coding for the S-fimbrial adhesin (sfa) in different Escherichia coli strains causing meningitis or urinary tract infections.
Infection and immunity 1986;54(3):646-53.
1986: Timo K Korhonen; J Parkkinen; Jörg Hacker; J Finne; AK Pere; Mikael Rhen; Harry Holthöfer
Binding of Escherichia coli S fimbriae to human kidney epithelium.
Infection and immunity 1986;54(2):322-7.