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Elizabeth Hadac

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Mulu Z Tesfay; Glen N Barber; Mark J Federspiel; guy griesmann; Elizabeth M Hadac; Stephen M Henry; Amber C Kirk; Kah-Whye Peng; Stephen J Russell
PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice.
Elizabeth M Hadac; Nicolai V Bovin; Evgeny Chernyy; Mark J Federspiel; Elena Korchagina; Stephen Russell; Alexander Tuzikov; Stephen M Henry
Fluorescein and radiolabeled Function-Spacer-Lipid constructs allow for simple in vitro and in vivo bioimaging of enveloped virions.
Elizabeth M Hadac; Elizabeth J Kelly; Stephen J Russell
Myeloma xenograft destruction by a nonviral vector delivering oncolytic infectious nucleic acid.

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All Publications

2013: Mulu Z Tesfay; Glen N Barber; Mark J Federspiel; guy griesmann; Elizabeth M Hadac; Stephen M Henry; Amber C Kirk; Kah-Whye Peng; Stephen J Russell
PEGylation of vesicular stomatitis virus extends virus persistence in blood circulation of passively immunized mice.
Journal of virology 2013;87(7):3752-9.
2011: Elizabeth M Hadac; Nicolai V Bovin; Evgeny Chernyy; Mark J Federspiel; Elena Korchagina; Stephen Russell; Alexander Tuzikov; Stephen M Henry
Fluorescein and radiolabeled Function-Spacer-Lipid constructs allow for simple in vitro and in vivo bioimaging of enveloped virions.
Journal of virological methods 2011;176(1-2):78-84.
2011: Elizabeth M Hadac; Elizabeth J Kelly; Stephen J Russell
Myeloma xenograft destruction by a nonviral vector delivering oncolytic infectious nucleic acid.
Molecular therapy : the journal of the American Society of Gene Therapy 2011;19(6):1041-7.
2010: Elizabeth J Kelly; Elizabeth M Hadac; Bryan R Cullen; Stephen J Russell
MicroRNA antagonism of the picornaviral life cycle: alternative mechanisms of interference.
PLoS pathogens 2010;6(3):e1000820.
2008: Elizabeth J Kelly; Elizabeth M Hadac; Suzanne Greiner; stephen russell
Engineering microRNA responsiveness to decrease virus pathogenicity.
Nature medicine 2008;14(11):1278-83.
2006: Stephanie K Carlson; Kelly L Classic; Elizabeth M Hadac; Claire E Bender; Brad J Kemp; Val J. Lowe; Tanya L Hoskin; stephen russell
In vivo quantitation of intratumoral radioisotope uptake using micro-single photon emission computed tomography/computed tomography.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2006;8(6):324-32.
2006: Kah-Whye Peng; Elizabeth M Hadac; Bambi D Anderson; Rae Myers; Mary Harvey; Suzanne Greiner; Diane Soeffker; Mark J Federspiel; stephen russell
Pharmacokinetics of oncolytic measles virotherapy: eventual equilibrium between virus and tumor in an ovarian cancer xenograft model.
Cancer gene therapy 2006;13(8):732-8.
2006: Elizabeth M Hadac; Eric S Dawson; James W Darrow; Elizabeth E Sugg; Terry P Lybrand; Laurence J Miller
Novel benzodiazepine photoaffinity probe stereoselectively labels a site deep within the membrane-spanning domain of the cholecystokinin receptor.
Journal of medicinal chemistry 2006;49(3):850-63.
2005: Maoqing Dong; Elizabeth M Hadac; Delia I Pinon; Laurence J Miller
Differential spatial approximation between cholecystokinin residue 30 and receptor residues in active and inactive conformations.
Molecular pharmacology 2005;67(6):1892-900.
2004: Elizabeth M Hadac; Kah-Whye Peng; Takafumi Nakamura; stephen russell
Reengineering paramyxovirus tropism.
Virology 2004;329(2):217-25.
2003: Mengwei Zang; Maoqing Dong; Delia I Pinon; Xi-Qin Ding; Elizabeth M Hadac; Zhijun Li; Terry P Lybrand; Laurence J Miller
Spatial approximation between a photolabile residue in position 13 of secretin and the amino terminus of the secretin receptor.
Molecular pharmacology 2003;63(5):993-1001.
2003: Xi-Qin Ding; Vesile Dolu; Elizabeth M Hadac; Michael Schuetz; Laurence J Miller
Disulfide bond structure and accessibility of cysteines in the ectodomain of the cholecystokinin receptor: specific mono-reactive receptor constructs examine charge-sensitivity of loop regions.
Receptors & channels 2003;9(2):83-91.
2001: Bernard Coulie; Bunzo Matsuura; Maoqing Dong; Elizabeth M Hadac; Delia I Pinon; Scott Feighner; Andrew D Howard; Laurence J Miller
Identification of peptide ligand-binding domains within the human motilin receptor using photoaffinity labeling.
The Journal of biological chemistry 2001;276(38):35518-22.
2001: Eileen L Holicky; Elizabeth M Hadac; Xi-Qin Ding; Laurence J Miller
Molecular characterization and organ distribution of type A and B cholecystokinin receptors in cynomolgus monkey.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(2):G507-14.
2001: Xi-Qin Ding; V Dolu; Elizabeth M Hadac; Eileen L Holicky; Delia I Pinon; Terry P Lybrand; Laurence J Miller
Refinement of the structure of the ligand-occupied cholecystokinin receptor using a photolabile amino-terminal probe.
The Journal of biological chemistry 2001;276(6):4236-44.
2001: Pamela S Tietz; Elizabeth M Hadac; Laurence J Miller; Nicholas F LaRusso
Upregulation of secretin receptors on cholangiocytes after bile duct ligation.
Regulatory peptides 2001;97(1):1-6.
2000: C G Park; SC Ganguli; Delia I Pinon; Elizabeth M Hadac; Laurence J Miller
Cross-chimeric analysis of selectivity of secretin and VPAC(1) receptor activation.
The Journal of pharmacology and experimental therapeutics 2000;295(2):682-8.
2000: Yan W Asmann; Maoqing Dong; SC Ganguli; Elizabeth M Hadac; Laurence J Miller
Structural insights into the amino-terminus of the secretin receptor: I. Status of cysteine and cystine residues.
Molecular pharmacology 2000;58(5):911-9.
1999: Maoqing Dong; Y Wang; Elizabeth M Hadac; Delia I Pinon; Eileen L Holicky; Laurence J Miller
Identification of an interaction between residue 6 of the natural peptide ligand and a distinct residue within the amino-terminal tail of the secretin receptor.
The Journal of biological chemistry 1999;274(27):19161-7.
1999: Elizabeth M Hadac; Z Ji; Delia I Pinon; Randel M Henne; Terry P Lybrand; Laurence J Miller
A peptide agonist acts by occupation of a monomeric G protein-coupled receptor: dual sites of covalent attachment to domains near TM1 and TM7 of the same molecule make biologically significant domain-swapped dimerization unlikely.
Journal of medicinal chemistry 1999;42(12):2105-11.
1999: Maoqing Dong; Xi-Qin Ding; Delia I Pinon; Elizabeth M Hadac; R P Oda; J P Landers; Laurence J Miller
Structurally related peptide agonist, partial agonist, and antagonist occupy a similar binding pocket within the cholecystokinin receptor. Rapid analysis using fluorescent photoaffinity labeling probes and capillary electrophoresis.
The Journal of biological chemistry 1999;274(8):4778-85.
1999: Maoqing Dong; Y Wang; Delia I Pinon; Elizabeth M Hadac; Laurence J Miller
Demonstration of a direct interaction between residue 22 in the carboxyl-terminal half of secretin and the amino-terminal tail of the secretin receptor using photoaffinity labeling.
The Journal of biological chemistry 1999;274(2):903-9.
1998: J W Darrow; Elizabeth M Hadac; L J Miller; E E Sugg
Structurally similar small molecule photoaffinity CCK-A agonists and antagonists as novel tools for directly probing 7TM receptors-ligand interactions.
Bioorganic & medicinal chemistry letters 1998;8(22):3127-32.
1998: SC Ganguli; C G Park; M H Holtmann; Elizabeth M Hadac; Terry Kenakin; Laurence J Miller
Protean effects of a natural peptide agonist of the G protein-coupled secretin receptor demonstrated by receptor mutagenesis.
The Journal of pharmacology and experimental therapeutics 1998;286(2):593-8.
1998: W Y Go; Eileen L Holicky; Elizabeth M Hadac; RV Rao; Laurence J Miller
Identification of a domain in the carboxy terminus of CCK receptor that affects its intracellular trafficking.
The American journal of physiology 1998;275(1 Pt 1):G56-62.
1998: Elizabeth M Hadac; Delia I Pinon; Z Ji; Eileen L Holicky; Randel M Henne; Terry P Lybrand; Laurence J Miller
Direct identification of a second distinct site of contact between cholecystokinin and its receptor.
The Journal of biological chemistry 1998;273(21):12988-93.
1997: Z Ji; Elizabeth M Hadac; Randel M Henne; S A Patel; Terry P Lybrand; Laurence J Miller
Direct identification of a distinct site of interaction between the carboxyl-terminal residue of cholecystokinin and the type A cholecystokinin receptor using photoaffinity labeling.
The Journal of biological chemistry 1997;272(39):24393-401.
1997: D Ghanekar; Elizabeth M Hadac; Eileen L Holicky; Laurence J Miller
Differences in partial agonist action at cholecystokinin receptors of mouse and rat are dependent on parameters extrinsic to receptor structure: molecular cloning, expression and functional characterization of the mouse type A cholecystokinin receptor.
The Journal of pharmacology and experimental therapeutics 1997;282(3):1206-12.
1997: RV Rao; Elizabeth M Hadac; BF Roettger; Laurence J Miller
Cholecystokinin-induced desensitization, receptor phosphorylation, and internalization in the CHP212 neuroblastoma cell line.
Journal of neurochemistry 1997;68(6):2356-62.
1997: W Y Go; BF Roettger; Eileen L Holicky; Elizabeth M Hadac; Laurence J Miller
Quantitative dynamic multicompartmental analysis of cholecystokinin receptor movement in a living cell using dual fluorophores and reconstruction of confocal images.
Analytical biochemistry 1997;247(2):210-5.
1997: RV Rao; BF Roettger; Elizabeth M Hadac; Laurence J Miller
Roles of cholecystokinin receptor phosphorylation in agonist-stimulated desensitization of pancreatic acinar cells and receptor-bearing Chinese hamster ovary cholecystokinin receptor cells.
Molecular pharmacology 1997;51(2):185-92.
1996: M H Holtmann; Elizabeth M Hadac; Charles D Ulrich; Laurence J Miller
Molecular basis and species specificity of high affinity binding of vasoactive intestinal polypeptide by the rat secretin receptor.
The Journal of pharmacology and experimental therapeutics 1996;279(2):555-60.
1996: Elizabeth M Hadac; D V Ghanekar; Eileen L Holicky; Delia I Pinon; R W Dougherty; Laurence J Miller
Relationship between native and recombinant cholecystokinin receptors: role of differential glycosylation.
Pancreas 1996;13(2):130-9.
1996: M H Holtmann; S Ganguli; Elizabeth M Hadac; V Dolu; Laurence J Miller
Multiple extracellular loop domains contribute critical determinants for agonist binding and activation of the secretin receptor.
The Journal of biological chemistry 1996;271(25):14944-9.
1995: BF Roettger; R U Rentsch; Elizabeth M Hadac; E H Hellen; T P Burghardt; Laurence J Miller
Insulation of a G protein-coupled receptor on the plasmalemmal surface of the pancreatic acinar cell.
The Journal of cell biology 1995;130(3):579-90.
1995: M H Holtmann; Elizabeth M Hadac; Laurence J Miller
Critical contributions of amino-terminal extracellular domains in agonist binding and activation of secretin and vasoactive intestinal polypeptide receptors. Studies of chimeric receptors.
The Journal of biological chemistry 1995;270(24):14394-8.
1995: BF Roettger; R U Rentsch; Delia I Pinon; Eileen L Holicky; Elizabeth M Hadac; J M Larkin; Laurence J Miller
Dual pathways of internalization of the cholecystokinin receptor.
The Journal of cell biology 1995;128(6):1029-41.
1994: Laurence J Miller; Elizabeth M Hadac; S P Powers
Preparation of radiolabeled photolabile probes of high specific radioactivity for affinity labeling.
Analytical biochemistry 1994;220(2):434-5.
1993: Charles D Ulrich; Delia I Pinon; Elizabeth M Hadac; Eileen L Holicky; A Chang-Miller; Lawrence K Gates; Laurence J Miller
Intrinsic photoaffinity labeling of native and recombinant rat pancreatic secretin receptors.
Gastroenterology 1993;105(5):1534-43.
1993: Charles D Ulrich; I Ferber; Eileen L Holicky; Elizabeth M Hadac; G Buell; Laurence J Miller
Molecular cloning and functional expression of the human gallbladder cholecystokinin A receptor.
Biochemical and biophysical research communications 1993;193(1):204-11.
1992: Laurence J Miller; Elizabeth M Hadac; Lawrence K Gates; H Y Gaisano
Binding of a phenethyl ester analogue of cholecystokinin to the solubilized pancreatic cholecystokinin receptor: use in ligand-affinity chromatography.
Biochemical and biophysical research communications 1992;183(2):396-404.
1989: R K Pearson; Elizabeth M Hadac; Laurence J Miller
Structural analysis of a distinct subtype of CCK receptor on human gastric smooth muscle tumors.
The American journal of physiology 1989;256(6 Pt 1):G1005-10.
1987: M J Shaw; Elizabeth M Hadac; Laurence J Miller
Preparation of enriched plasma membranes from bovine gallbladder muscularis for characterization of cholecystokinin receptors.
The Journal of biological chemistry 1987;262(29):14313-8.
1987: R K Pearson; Laurence J Miller; Elizabeth M Hadac; S P Powers
Analysis of the carbohydrate composition of the pancreatic plasmalemmal glycoprotein affinity labeled by short probes for the cholecystokinin receptor.
The Journal of biological chemistry 1987;262(28):13850-6.
1987: R K Pearson; S P Powers; Elizabeth M Hadac; H Gaisano; Laurence J Miller
Establishment of a new short, protease-resistant, affinity labeling reagent for the cholecystokinin receptor.
Biochemical and biophysical research communications 1987;147(1):346-53.
1987: R K Pearson; Laurence J Miller; S P Powers; Elizabeth M Hadac
Biochemical characterization of the pancreatic cholecystokinin receptor using monofunctional photoactivatable probes.
Pancreas 1987;2(1):79-84.
1986: R K Pearson; Elizabeth M Hadac; Laurence J Miller
Preparation and characterization of a new cholecystokinin receptor probe that can be oxidatively radioiodinated.
Gastroenterology 1986;90(6):1985-91.