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Jonathan Hadgraft

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Physiology

Skin Absorption

Procedures

Phenomena

Concepts & Ideas

Objects

Artificial Membranes

Anatomy

Chemicals & Drugs

Occupations

Pharmaceutical Chemistry

Devices

Culture Diffusion Chambers

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Network (preview)

Co-Publications
Name
13
Lane, Majella
11
Raghavan, SL
11
Du Plessis, Jeanetta
8
Valenta, Claudia
7
Pugh, John
7
Dias, Monica
5
Davis, AF
4
Breytenbach, Jaco
4
Goosen, Colleen
4
Herkenne, Christophe
4
Guy, Richard
4
Kalia, Yogeshvar
4
Naik, Aarti
3
O'Neill, Michael
3
Pellett, MA

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Publications

TOP 3
McAuley William J; Mader Kerstin T; Tetteh John; Lane Majella E; Hadgraft Jonathan
Simultaneous monitoring of drug and solvent diffusion across a model membrane using ATR-FTIR spectroscopy.
Cork Michael J; Danby Simon G; Vasilopoulos Yiannis; Hadgraft Jonathan; Lane Majella E; Moustafa Manar; Guy Richard H; Macgowan Alice L; Tazi-Ahnini Rachid; Ward Simon J
Epidermal barrier dysfunction in atopic dermatitis.
Santos P; Machado M; Watkinson A C; Hadgraft J; Lane M E
The effect of drug concentration on solvent activity in silicone membranes.

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All Publications

2009: McAuley William J; Mader Kerstin T; Tetteh John; Lane Majella E; Hadgraft Jonathan
Simultaneous monitoring of drug and solvent diffusion across a model membrane using ATR-FTIR spectroscopy.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2009;38(4):378-83.
2009: Cork Michael J; Danby Simon G; Vasilopoulos Yiannis; Hadgraft Jonathan; Lane Majella E; Moustafa Manar; Guy Richard H; Macgowan Alice L; Tazi-Ahnini Rachid; Ward Simon J
Epidermal barrier dysfunction in atopic dermatitis.
The Journal of investigative dermatology 2009;129(8):1892-908.
2009: Santos P; Machado M; Watkinson A C; Hadgraft J; Lane M E
The effect of drug concentration on solvent activity in silicone membranes.
International journal of pharmaceutics 2009;377(1-2):70-5.
2009: Russeau Wanessa; Mitchell John; Tetteh John; Lane Majella E; Hadgraft Jonathan
Investigation of the permeation of model formulations and a commercial ibuprofen formulation in Carbosil and human skin using ATR-FTIR and multivariate spectral analysis.
International journal of pharmaceutics 2009;374(1-2):17-25.
2009: Andanson Jean-Michel; Hadgraft Jonathan; Kazarian Sergei G
In situ permeation study of drug through the stratum corneum using attenuated total reflectance [corrected] Fourier transform infrared spectroscopic imaging.
Journal of biomedical optics 2009;14(3):034011.
2009: Hadgraft Jonathan; Lane Majella E
Transepidermal water loss and skin site: a hypothesis.
International journal of pharmaceutics 2009;373(1-2):1-3.
2009: Tetteh J; Mader K T; Andanson J-M; McAuley W J; Lane M E; Hadgraft J; Kazarian S G; Mitchell J C
Local examination of skin diffusion using FTIR spectroscopic imaging and multivariate target factor analysis.
Analytica chimica acta 2009;642(1-2):246-56.
2008: Zadeh Behzad Sharif Makhmal; Moghimi Hamidreza; Santos Paulo; Hadgraft Jonathan; Lane Majella E
A comparative study of the in vitro permeation characteristic of sulphadiazine across synthetic membranes and eschar tissue.
International wound journal 2008;5(5):633-8.
2008: Dias M; Naik A; Guy R H; Hadgraft J; Lane M E
In vivo infrared spectroscopy studies of alkanol effects on human skin.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2008;69(3):1171-5.
2008: Walker Mike; Hadgraft Jonathan; Lane Majella E
Investigation of the permeability characteristics of peri-ulcer and whole ischaemic skin tissue.
International journal of pharmaceutics 2008;357(1-2):1-5.
2008: Herkenne Christophe; Naik Aarti; Kalia Yogeshvar N; Hadgraft Jonathan; Guy Richard H
Effect of propylene glycol on ibuprofen absorption into human skin in vivo.
Journal of pharmaceutical sciences 2008;97(1):185-97.
2008: Otto A; Wiechers J W; Kelly C L; Hadgraft J; du Plessis J
Effect of penetration modifiers on the dermal and transdermal delivery of drugs and cosmetic active ingredients.
Skin pharmacology and physiology 2008;21(6):326-34.
2007: Ita Kevin B; Du Preez Jan; Lane Majella E; Hadgraft Jonathan; du Plessis Jeanetta
Dermal delivery of selected hydrophilic drugs from elastic liposomes: effect of phospholipid formulation and surfactants.
The Journal of pharmacy and pharmacology 2007;59(9):1215-22.
2007: Dias M; Hadgraft J; Lane M E
Influence of membrane-solvent-solute interactions on solute permeation in skin.
International journal of pharmaceutics 2007;340(1-2):65-70.
2007: Dias Monica; Hadgraft Jonathan; Lane Majella E
Influence of membrane-solvent-solute interactions on solute permeation in model membranes.
International journal of pharmaceutics 2007;336(1):108-14.
2007: Herkenne Christophe; Naik Aarti; Kalia Yogeshvar N; Hadgraft Jonathan; Guy Richard H
Dermatopharmacokinetic prediction of topical drug bioavailability in vivo.
The Journal of investigative dermatology 2007;127(4):887-94.
2007: Basketter David; Pease Camilla; Kasting Gerald; Kimber Ian; Casati Silvia; Cronin Mark; Diembeck Walter; Gerberick Frank; Hadgraft Jonathan; Hartung Thomas; Marty Jean-Paul; Nikolaidis Efstathios; Patlewicz Grace; Roberts David; Roggen Erwin; Rovida Costanza; van de Sandt Johannes
Skin sensitisation and epidermal disposition: the relevance of epidermal disposition for sensitisation hazard identification and risk assessment. The report and recommendations of ECVAM workshop 59.
Alternatives to laboratory animals : ATLA 2007;35(1):137-54.
2007: Dhuna Meena; Beezer Anthony E; Morris Andrew C; Gaisford Simon; O'Neill Michael A A; Hadgraft Jonathan; Connor Joseph A; Clapham David; Frost John
Development of an isothermal heat-conduction photocalorimeter.
The Review of scientific instruments 2007;78(2):025105.
2007: Herkenne Christophe; Naik Aarti; Kalia Yogeshvar N; Hadgraft Jonathan; Guy Richard H
Ibuprofen transport into and through skin from topical formulations: in vitro-in vivo comparison.
The Journal of investigative dermatology 2007;127(1):135-42.
2006: Herkenne Christophe; Naik Aarti; Kalia Yogeshvar N; Hadgraft Jonathan; Guy Richard H
Pig ear skin ex vivo as a model for in vivo dermatopharmacokinetic studies in man.
Pharmaceutical research 2006;23(8):1850-6.
2006: Leveque N; Raghavan S L; Lane M E; Hadgraft J
Use of a molecular form technique for the penetration of supersaturated solutions of salicylic acid across silicone membranes and human skin in vitro.
International journal of pharmaceutics 2006;318(1-2):49-54.
2006: Gerber Minja; Breytenbach Jaco C; Hadgraft Jonathan; du Plessis Jeanetta
Synthesis and transdermal properties of acetylsalicylic acid and selected esters.
International journal of pharmaceutics 2006;310(1-2):31-6.
2006: Májeková Magdaléna; Koprda Vasil; Bohácik L'ubor; Bohov Pavol; Hadgraft Jonathan; Bezáková Zelmíra; Májek Pavol
Skin permeation of acyl derivatives of stobadine.
Drug delivery 2006;13(1):51-4.
2005: Hadgraft Jonathan; Lane Majella E
Skin permeation: the years of enlightenment.
International journal of pharmaceutics 2005;305(1-2):2-12.
2005: Swart Henk; Breytenbach Jaco C; Hadgraft Jonathan; du Plessis Jeanetta
Synthesis and transdermal penetration of NSAID glycoside esters.
International journal of pharmaceutics 2005;301(1-2):71-9.
2005: Auner Barbara G; O'Neill Michael A A; Valenta Claudia; Hadgraft Jonathan
Interaction of phloretin and 6-ketocholestanol with DPPC-liposomes as phospholipid model membranes.
International journal of pharmaceutics 2005;294(1-2):149-55.
2005: Lopez V Castro; Hadgraft J; Snowden M J
The use of colloidal microgels as a (trans)dermal drug delivery system.
International journal of pharmaceutics 2005;292(1-2):137-47.
2005: Monene L Mishack; Goosen Colleen; Breytenbach Jaco C; Hadgraft Jonathan; du Plessis Jeanetta
Percutaneous absorption of cyclizine and its alkyl analogues.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2005;24(2-3):239-44.
2004: Hadgraft Jonathan
Skin deep.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2004;58(2):291-9.
2004: Backhouse L; Dias M; Gorce J P; Hadgraft J; McDonald P J; Wiechers J W
GARField magnetic resonance profiling of the ingress of model skin-care product ingredients into human skin in vitro.
Journal of pharmaceutical sciences 2004;93(9):2274-83.
2004: Fourie L; Breytenbach J C; Du Plessis J; Goosen C; Swart H; Hadgraft J
Percutaneous delivery of carbamazepine and selected N-alkyl and N-hydroxyalkyl analogues.
International journal of pharmaceutics 2004;279(1-2):59-66.
2004: Trottet L; Merly C; Mirza M; Hadgraft J; Davis A F
Effect of finite doses of propylene glycol on enhancement of in vitro percutaneous permeation of loperamide hydrochloride.
International journal of pharmaceutics 2004;274(1-2):213-9.
2004: Leveque N; Makki S; Hadgraft J; Humbert Ph
Comparison of Franz cells and microdialysis for assessing salicylic acid penetration through human skin.
International journal of pharmaceutics 2004;269(2):323-8.
2004: Dias M; Hadgraft J; Raghavan S L; Tetteh J
The effect of solvent on permeant diffusion through membranes studied using ATR-FTIR and chemometric data analysis.
Journal of pharmaceutical sciences 2004;93(1):186-96.
2004: Hadgraft Jonathan; Guy Richard
Biotechnological aspects of transport across human skin.
Biotechnology & genetic engineering reviews 2004;21():183-93.
2003: Rosado Catarina; Cross Sheree E; Pugh W John; Roberts Michael S; Hadgraft Jonathan
Effect of vehicle pretreatment on the flux, retention, and diffusion of topically applied penetrants in vitro.
Pharmaceutical research 2003;20(9):1502-7.
2003: Dias M M R; Raghavan S L; Pellett M A; Hadgraft J
The effect of beta-cyclodextrins on the permeation of diclofenac from supersaturated solutions.
International journal of pharmaceutics 2003;263(1-2):173-81.
2003: O'Neill Michael A A; Vine George J; Beezer Anthony E; Bishop Alistair H; Hadgraft Jonathan; Labetoulle Chloé; Walker Michael; Bowler Phillip G
Antimicrobial properties of silver-containing wound dressings: a microcalorimetric study.
International journal of pharmaceutics 2003;263(1-2):61-8.
2003: Raghavan S L; Schuessel K; Davis A; Hadgraft J
Formation and stabilisation of triclosan colloidal suspensions using supersaturated systems.
International journal of pharmaceutics 2003;261(1-2):153-8.
2003: Cladera Josep; O'Shea Paul; Hadgraft Jonathan; Valenta Claudia
Influence of molecular dipoles on human skin permeability: Use of 6-ketocholestanol to enhance the transdermal delivery of bacitracin.
Journal of pharmaceutical sciences 2003;92(5):1018-27.
2003: Hadgraft J; Whitefield M; Rosher P H
Skin penetration of topical formulations of ibuprofen 5%: an in vitro comparative study.
Skin pharmacology and applied skin physiology 2003;16(3):137-42.
2003: Farinha Ascensão; Toscano Cristina; Campos Rodrigo; Bica António; Hadgraft Jonathan
Permeation of naproxen from saturated solutions and commercial formulations through synthetic membranes.
Drug development and industrial pharmacy 2003;29(4):489-94.
2003: Auner Barbara G; Valenta Claudia; Hadgraft Jonathan
Influence of phloretin and 6-ketocholestanol on the skin permeation of sodium-fluorescein.
Journal of controlled release : official journal of the Controlled Release Society 2003;89(2):321-8.
2003: Auner B G; Valenta C; Hadgraft J
Influence of lipophilic counter-ions in combination with phloretin and 6-ketocholestanol on the skin permeation of 5-aminolevulinic acid.
International journal of pharmaceutics 2003;255(1-2):109-16.
2003: Hadgraft J; Goosen C; du Plessis J; Flynn G
Predicting the dermal absorption of thalidomide and its derivatives.
Skin pharmacology and applied skin physiology 2003;16(2):123-9.
2003: Degím Tuncer; Hadgraft Jonathan; Ilbasmis Sibel; Ozkan Yalçin
Prediction of skin penetration using artificial neural network (ANN) modeling.
Journal of pharmaceutical sciences 2003;92(3):656-64.
2002: du Plessis Jeanetta; Pugh W John; Judefeind Anja; Hadgraft Jonathan
Physico-chemical determinants of dermal drug delivery: effects of the number and substitution pattern of polar groups.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;16(3):107-12.
2002: Du Plessis Jeanetta; Pugh W John; Judefeind Anja; Hadgraft Jonathan
The effect of the nature of H-bonding groups on diffusion through PDMS membranes saturated with octanol and toluene.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2002;15(1):63-9.
2001: Kierstan K T; Beezer A E; Mitchell J C; Hadgraft J; Raghavan S L; Davis A F
UV-spectrophotometry study of membrane transport processes with a novel diffusion cell.
International journal of pharmaceutics 2001;229(1-2):87-94.
2001: Cross S E; Pugh W J; Hadgraft J; Roberts M S
Probing the effect of vehicles on topical delivery: understanding the basic relationship between solvent and solute penetration using silicone membranes.
Pharmaceutical research 2001;18(7):999-1005.
2001: Raghavan S L; Kiepfer B; Davis A F; Kazarian S G; Hadgraft J
Membrane transport of hydrocortisone acetate from supersaturated solutions; the role of polymers.
International journal of pharmaceutics 2001;221(1-2):95-105.
2001: Du Plessis J; Pugh W J; Judefeind A; Hadgraft J
The effect of hydrogen bonding on diffusion across model membranes: consideration of the number of H-bonding groups.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2001;13(2):135-41.
2001: Valenta C; Nowak M; Hadgraft J
Influence of phloretin and 6-ketocholestanol on the permeation of progesterone through porcine skin.
International journal of pharmaceutics 2001;217(1-2):79-86.
2001: Valenta C; Cladera J; O'Shea P; Hadgraft J
Effect of phloretin on the percutaneous absorption of lignocaine across human skin.
Journal of pharmaceutical sciences 2001;90(4):485-92.
2001: Dias M; Raghavan S L; Hadgraft J
ATR-FTIR spectroscopic investigations on the effect of solvents on the permeation of benzoic acid and salicylic acid through silicone membranes.
International journal of pharmaceutics 2001;216(1-2):51-9.
2001: Iervolino M; Cappello B; Raghavan S L; Hadgraft J
Penetration enhancement of ibuprofen from supersaturated solutions through human skin.
International journal of pharmaceutics 2001;212(1):131-41.
2001: Raghavan S L; Trividic A; Davis A F; Hadgraft J
Crystallization of hydrocortisone acetate: influence of polymers.
International journal of pharmaceutics 2001;212(2):213-21.
2001: Hadgraft J
Modulation of the barrier function of the skin.
Skin pharmacology and applied skin physiology 2001;14 Suppl 1():72-81.
2000: Ramsay E; Hadgraft J; Birchall J; Gumbleton M
Examination of the biophysical interaction between plasmid DNA and the polycations, polylysine and polyornithine, as a basis for their differential gene transfection in-vitro.
International journal of pharmaceutics 2000;210(1-2):97-107.
2000: Hadgraft J; du Plessis J; Goosen C
The selection of non-steroidal anti-inflammatory agents for dermal delivery.
International journal of pharmaceutics 2000;207(1-2):31-7.
2000: Hadgraft J; Valenta C
pH, pK(a) and dermal delivery.
International journal of pharmaceutics 2000;200(2):243-7.
2000: Iervolino M; Raghavan S L; Hadgraft J
Membrane penetration enhancement of ibuprofen using supersaturation.
International journal of pharmaceutics 2000;198(2):229-38.
2000: Birchall J C; Marichal C; Campbell L; Alwan A; Hadgraft J; Gumbleton M
Gene expression in an intact ex-vivo skin tissue model following percutaneous delivery of cationic liposome-plasmid DNA complexes.
International journal of pharmaceutics 2000;197(1-2):233-8.
2000: Pugh W J; Degim I T; Hadgraft J
Epidermal permeability-penetrant structure relationships: 4, QSAR of permeant diffusion across human stratum corneum in terms of molecular weight, H-bonding and electronic charge.
International journal of pharmaceutics 2000;197(1-2):203-11.
2000: Valenta C; Siman U; Kratzel M; Hadgraft J
The dermal delivery of lignocaine: influence of ion pairing.
International journal of pharmaceutics 2000;197(1-2):77-85.
2000: Raghavan S L; Trividic A; Davis A F; Hadgraft J
Effect of cellulose polymers on supersaturation and in vitro membrane transport of hydrocortisone acetate.
International journal of pharmaceutics 2000;193(2):231-7.
1999: Pellett M A; Hadgraft J; Roberts M S
The back diffusion of glucose across human skin in vitro.
International journal of pharmaceutics 1999;193(1):27-35.
1999: Degim I T; Hadgraft J; Houghton E; Teale P
In vitro percutaneous absorption of fusidic acid and betamethasone 17-valerate across canine skin.
The Journal of small animal practice 1999;40(11):515-8.
1999: Hadgraft J
Passive enhancement strategies in topical and transdermal drug delivery.
International journal of pharmaceutics 1999;184(1):1-6.
1999: Dias M; Farinha A; Faustino E; Hadgraft J; Pais J; Toscano C
Topical delivery of caffeine from some commercial formulations.
International journal of pharmaceutics 1999;182(1):41-7.
1999: Degim I T; Uslu A; Hadgraft J; Atay T; Akay C; Cevheroglu S
The effects of Azone and capsaicin on the permeation of naproxen through human skin.
International journal of pharmaceutics 1999;179(1):21-5.
1998: Hadgraft J; Pugh W J
The selection and design of topical and transdermal agents: a review.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 1998;3(2):131-5.
1997: López A; Pellett M A; Llinares F; Díez-Sales O; Herráez M; Hadgraft J
The enhancer effect of several phenyl alcohols on percutaneous penetration of 5-fluorouracil.
Pharmaceutical research 1997;14(5):681-5.

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