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Dimitra Hadjipavlou-Litina

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A Repanas; A M Katsori; Dimitra Hadjipavlou-Litina
Chalcones in Cancer: Understanding their Role in Terms of QSAR. II Part.
Ivana Perković; Sara Tršinar; Jelena Žanetić; Jan Balzarini; Dimitra Hadjipavlou-Litina; Anna-Maria Katsori; Marijeta Kralj; Irena Martin-Kleiner; Branka Zorc
Novel 1-acyl-4-substituted semicarbazide derivatives of primaquine - synthesis, cytostatic, antiviral and antioxidative studies.
Stavros E Bariamis; Constantinos M Athanassopoulos; Konstantinos Avgoustakis; Christos A Kontogiorgis; Marilena Marin; Dionissios Papaioannou; Giovanni Romeo; Giovanni Sindona; Zinovia Tsimali; Dimitra Hadjipavlou-Litina
Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives.

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All Publications

2013: A Repanas; A M Katsori; Dimitra Hadjipavlou-Litina
Chalcones in Cancer: Understanding their Role in Terms of QSAR. II Part.
Mini reviews in medicinal chemistry 2013;13(7):952-70.
2013: Ivana Perković; Sara Tršinar; Jelena Žanetić; Jan Balzarini; Dimitra Hadjipavlou-Litina; Anna-Maria Katsori; Marijeta Kralj; Irena Martin-Kleiner; Branka Zorc
Novel 1-acyl-4-substituted semicarbazide derivatives of primaquine - synthesis, cytostatic, antiviral and antioxidative studies.
Journal of enzyme inhibition and medicinal chemistry 2013;28(3):601-10.
2013: Stavros E Bariamis; Constantinos M Athanassopoulos; Konstantinos Avgoustakis; Christos A Kontogiorgis; Marilena Marin; Dionissios Papaioannou; Giovanni Romeo; Giovanni Sindona; Zinovia Tsimali; Dimitra Hadjipavlou-Litina
Syntheses and evaluation of the antioxidant activity of novel methoxypsoralen derivatives.
European journal of medicinal chemistry 2013;60():155-69.
2013: I Apostolidis; Antonios M Gavalas; Athina Geronikaki; J Glamočlija; Dimitra Hadjipavlou-Litina; Konstantinos Liaras; M Soković; A Ćirić
Synthesis and biological evaluation of some 5-arylidene-2-(1,3-thiazol-2-ylimino)-1,3-thiazolidin-4-ones as dual anti-inflammatory/antimicrobial agents.
Bioorganic & medicinal chemistry 2013;21(2):532-9.
2013: Eleni Pontiki; Yanan Xu; Dimitra Hadjipavlou-Litina; Christos A Kontogiorgis; Yuan Luo
New lipoxygenase inhibitors of reactive oxygen species production in cellular models of amyloid (A2) toxicities.
Journal of Alzheimer's disease : JAD 2013;34(1):215-30.
2013: Sophia Karastogianni; Catherine P Raptopoulou; Catherine Dendrinou-Samara; Dimitra Hadjipavlou-Litina; Eleutheria Ioannou; S Th Girousi
Synthesis, characterization, DNA binding properties and antioxidant activity of a manganese(II) complex with NO6 chromophore.
Journal of inorganic biochemistry 2013;118():48-58.
2012: Dimitra Georgiou; Dimitra Hadjipavlou-Litina; Kenneth W Muir; Vasilios Toutountzoglou; Yiannis Elemes
Synthesis of sulfur containing dihydro-pyrrolo derivatives and their biological evaluation as antioxidants.
Bioorganic & medicinal chemistry 2012;20(17):5103-9.
2012: I Perković; Jan Balzarini; I Butula; Dimitra Hadjipavlou-Litina; Anna-Maria Katsori; Marijeta Kralj; I Martin-Kleiner; Branka Zorc
Novel NSAID 1-acyl-4-cycloalkyl/arylsemicarbazides and 1-acyl-5-benzyloxy/hydroxy carbamoylcarbazides as potential anticancer agents and antioxidants.
European journal of medicinal chemistry 2012;51():227-38.
2012: Christos A Kontogiorgis; Anastasia Detsi; Dimitra Hadjipavlou-Litina
Coumarin-based drugs: a patent review (2008 -- present).
Expert opinion on therapeutic patents 2012;22(4):437-54.
2012: Phaedra T Eleftheriou; Dmitrii A Filimonov; Olga Filz; Athina Geronikaki; Dimitra Hadjipavlou-Litina; Vladimir Poroikov; Kuldeep K Roy; Shailendra s chaudhaery; Paola Vicini; Anil K Saxena
Fragment-based design, docking, synthesis, biological evaluation and structure-activity relationships of 2-benzo/benzisothiazolimino-5-aryliden-4-thiazolidinones as cycloxygenase/lipoxygenase inhibitors.
European journal of medicinal chemistry 2012;47(1):111-24.
2011: Anna Balabani; Dimitra Hadjipavlou-Litina; Konstantinos E Litinas; Maria Mainou; Crystal-Catherine Tsironi; Anastasia Vronteli
Synthesis and biological evaluation of (2,5-dihydro-1H-pyrrol-1-yl)-2H-chromen-2-ones as free radical scavengers.
European journal of medicinal chemistry 2011;46(12):5894-901.
2011: Konstantinos E Litinas; Alexandros Mangos; Thomas E Nikkou; Dimitra Hadjipavlou-Litina
Synthesis and biological evaluation of fused oxepinocoumarins as free radicals scavengers.
Journal of enzyme inhibition and medicinal chemistry 2011;26(6):805-12.
2011: Anna-Maria Katsori; Dimitra Hadjipavlou-Litina
Recent progress in therapeutic applications of chalcones.
Expert opinion on therapeutic patents 2011;21(10):1575-96.
2011: Miloš Ilić; Dimitra Hadjipavlou-Litina; Janez Ilaš; Christos A Kontogiorgis; Danijel Kikelj
Thrombin inhibitors with lipid peroxidation and lipoxygenase inhibitory activities.
Bioorganic & medicinal chemistry letters 2011;21(16):4705-9.
2011: Anna-Maria Katsori; Maria Chatzopoulou; K Dimas; Christos A Kontogiorgis; A Patsilinakos; T Trangas; Dimitra Hadjipavlou-Litina
Curcumin analogues as possible anti-proliferative & anti-inflammatory agents.
European journal of medicinal chemistry 2011;46(7):2722-35.
2011: Z Boulsourani; George Geromichalos; Katerina Repana; E Yiannaki; Vassilis Psycharis; Catherine P Raptopoulou; Dimitra Hadjipavlou-Litina; Eleni Pontiki; Catherine Dendrinou-Samara
Preparation and pharmacochemical evaluation of mixed ligand copper(II) complexes with triethanolamine and thiophenyl-2 saturated carboxylic acids.
Journal of inorganic biochemistry 2011;105(6):839-49.
2011: Panagiota Moutevelis-Minakakis; Eleni Papavassilopoulou; George Michas; Kalliopi Georgikopoulou; Maria-Eleni Ragoussi; Niki Neophytou; Panagiotis Zoumpoulakis; Thomas Mavromoustakos; Dimitra Hadjipavlou-Litina
Synthesis, in silico docking experiments of new 2-pyrrolidinone derivatives and study of their anti-inflammatory activity.
Bioorganic & medicinal chemistry 2011;19(9):2888-902.
2011: Asunción Burguete; Eleni Pontiki; Dimitra Hadjipavlou-Litina; Saioa Ancizu; Raquel Villar; Beatriz Solano; Elsa Moreno; Enrique Torres; Silvia Pérez; Ignacio Aldana; Antonio Monge
Synthesis and biological evaluation of new quinoxaline derivatives as antioxidant and anti-inflammatory agents.
Chemical biology & drug design 2011;77(4):255-67.
2011: Constantinos G Neochoritis; Tryfon Zarganes-Tzitzikas; Constantinos A Tsoleridis; Julia Stephanidou-Stephanatou; Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina; Theodora Choli-Papadopoulou
One-pot microwave assisted synthesis under green chemistry conditions, antioxidant screening, and cytotoxicity assessments of benzimidazole Schiff bases and pyrimido[1,2-a]benzimidazol-3(4H)-ones.
European journal of medicinal chemistry 2011;46(1):297-306.
2011: Eleni Pontiki; Dimitra Hadjipavlou-Litina; Konstantinos Litinas; Orazio Nicolotti; Angelo Carotti
Design, synthesis and pharmacobiological evaluation of novel acrylic acid derivatives acting as lipoxygenase and cyclooxygenase-1 inhibitors with antioxidant and anti-inflammatory activities.
European journal of medicinal chemistry 2011;46(1):191-200.
2010: Dimitra Hadjipavlou-Litina; George E Magoulas; Stavros E Bariamis; Denis Drainas; Konstantinos Avgoustakis; Dionissios Papaioannou
Does conjugation of antioxidants improve their antioxidative/anti-inflammatory potential?
Bioorganic & medicinal chemistry 2010;18(23):8204-17.
2010: Maria Ispikoudi; Michalis Amvrazis; Christos Kontogiorgis; Alexandros E Koumbis; Konstantinos E Litinas; Dimitra Hadjipavlou-Litina; Konstantina C Fylaktakidou
Convenient synthesis and biological profile of 5-amino-substituted 1,2,4-oxadiazole derivatives.
European journal of medicinal chemistry 2010;45(12):5635-45.
2010: Marina Roussaki; Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina; Stylianos Hamilakis; Anastasia Detsi
A novel synthesis of 3-aryl coumarins and evaluation of their antioxidant and lipoxygenase inhibitory activity.
Bioorganic & medicinal chemistry letters 2010;20(13):3889-92.
2010: Zrinka Rajić; Dimitra Hadjipavlou-Litina; Eleni Pontiki; Marijeta Kralj; Lidija Suman; Branka Zorc
The novel ketoprofen amides--synthesis and biological evaluation as antioxidants, lipoxygenase inhibitors and cytostatic agents.
Chemical biology & drug design 2010;75(6):641-52.
2010: A J Michael; Constantinos Alexopoulos; Eleni Pontiki; Dimitra Hadjipavlou-Litina; Ph Saratsis; Haralabos N Ververidis; Costas M Boscos
Effect of N-acetyl-L-cysteine supplementation in semen extenders on semen quality and reactive oxygen species of chilled canine spermatozoa.
Reproduction in domestic animals = Zuchthygiene 2010;45(2):201-7.
2010: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Thromboxane synthase inhibitors and thromboxane A2 receptor antagonists: a quantitative structure activity relationships (QSARs) analysis.
Current medicinal chemistry 2010;17(28):3162-214.
2010: Dimitra Hadjipavlou-Litina; George E Magoulas; Marios Krokidis; Dionissios Papaioannou
Syntheses and evaluation of the antioxidant activity of acitretin analogs with amide bond(s) in the polyene spacer.
European journal of medicinal chemistry 2010;45(1):298-310.
2009: Dimitra Hadjipavlou-Litina; S E Bariamis; M Militsopoulou; C M Athanassopoulos; D Papaioannou
Trioxsalen derivatives with lipoxygenase inhibitory activity.
Journal of enzyme inhibition and medicinal chemistry 2009;24(6):1351-6.
2009: Anastasia Detsi; Maya Majdalani; Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina; Panagiotis Kefalas
Natural and synthetic 2'-hydroxy-chalcones and aurones: synthesis, characterization and evaluation of the antioxidant and soybean lipoxygenase inhibitory activity.
Bioorganic & medicinal chemistry 2009;17(23):8073-85.
2009: Theodoros Symeonidis; Konstantina C Fylaktakidou; Dimitra Hadjipavlou-Litina; Konstantinos E Litinas
Synthesis and anti-inflammatory evaluation of novel angularly or linearly fused coumarins.
European journal of medicinal chemistry 2009;44(12):5012-7.
2009: Andreas Thalassitis; Dimitra Hadjipavlou-Litina; Konstantinos E Litinas; Panagiotis Miltiadou
Synthesis of modified homo-N-nucleosides from the reactions of mesityl nitrile oxide with 9-allylpurines and their influence on lipid peroxidation and thrombin inhibition.
Bioorganic & medicinal chemistry letters 2009;19(22):6433-6.
2009: Elizabeth Malamidou-Xenikaki; Spyros Spyroudis; Maria Tsanakopoulou; Dimitra Hadjipavlou-Litina
A convenient approach to fused indeno-1,4-diazepinones through hypervalent iodine chemistry.
The Journal of organic chemistry 2009;74(19):7315-21.
2009: Dimitra Hadjipavlou-Litina; Thomas Garnelis; Constantinos M Athanassopoulos; Dionissios Papaioannou
Kukoamine A analogs with lipoxygenase inhibitory activity.
Journal of enzyme inhibition and medicinal chemistry 2009;24(5):1188-93.
2009: Zrinka Rajić; Ivana Perković; Ivan Butula; Branka Zorc; Dimitra Hadjipavlou-Litina; Eleni Pontiki; Stjepan Pepeljnjak; Ivan Kosalec
Synthesis and biological evaluation of O-methyl and O-ethyl NSAID hydroxamic acids.
Journal of enzyme inhibition and medicinal chemistry 2009;24(5):1179-87.
2009: Zorica D Petrović; Dimitra Hadjipavlou-Litina; Eleni Pontiki; Dusica Simijonović; Vladimir P Petrović
Diethanolamine Pd(II) complexes in bioorganic modeling as model systems of metallopeptidases and soybean lipoxygenase inhibitors.
Bioorganic chemistry 2009;37(5):162-6.
2009: Eleni Pontiki; Dimitra Hadjipavlou-Litina; George Geromichalos; Athanasios Papageorgiou
Anticancer activity and quantitative-structure activity relationship (QSAR) studies of a series of antioxidant/anti-inflammatory aryl-acetic and hydroxamic acids.
Chemical biology & drug design 2009;74(3):266-75.
2009: Dimitra Hadjipavlou-Litina; Paolo Braiuca; Lucia Lassiani; Michela V Pavan; Antonio Varnavas
2D-QSAR and 3D-QSAR/CoMFA analyses of the N-terminal substituted anthranilic acid based CCK(1) receptor antagonists: 'Hic Rhodus, hic saltus'.
Bioorganic & medicinal chemistry 2009;17(14):5198-206.
2009: Georgia Melagraki; Antreas Afantitis; Olga Igglessi-Markopoulou; Anastasia Detsi; Maria Koufaki; Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Synthesis and evaluation of the antioxidant and anti-inflammatory activity of novel coumarin-3-aminoamides and their alpha-lipoic acid adducts.
European journal of medicinal chemistry 2009;44(7):3020-6.
2009: Dimitra Kovala-Demertzi; Dimitra Hadjipavlou-Litina; Alexandra Primikiri; Malgorzata Staninska; Chronis Kotoglou; Mavroudis A Demertzis
Anti-inflammatory, antiproliferative, and radical-scavenging activities of tolfenamic acid and its metal complexes.
Chemistry & biodiversity 2009;6(6):948-60.
2009: Dimitra Kovala-Demertzi; Dimitra Hadjipavlou-Litina; Malgorzata Staninska; Alexandra Primikiri; Chronis Kotoglou; Mavroudis A Demertzis
Anti-oxidant, in vitro, in vivo anti-inflammatory activity and antiproliferative activity of mefenamic acid and its metal complexes with manganese(II), cobalt(II), nickel(II), copper(II) and zinc(II).
Journal of enzyme inhibition and medicinal chemistry 2009;24(3):742-52.
2009: A J Michael; Constantinos Alexopoulos; Eleni Pontiki; Dimitra Hadjipavlou-Litina; Ph Saratsis; Haralabos N Ververidis; Costas M Boscos
Effect of antioxidant supplementation in semen extenders on semen quality and reactive oxygen species of chilled canine spermatozoa.
Animal reproduction science 2009;112(1-2):119-35.
2009: Omar Kouatly; Athina Geronikaki; Charalambos Kamoutsis; Dimitra Hadjipavlou-Litina; Phaedra T Eleftheriou
Adamantane derivatives of thiazolyl-N-substituted amide, as possible non-steroidal anti-inflammatory agents.
European journal of medicinal chemistry 2009;44(3):1198-204.
2009: Theodoros Symeonidis; Michael Chamilos; Dimitra Hadjipavlou-Litina; Michael Kallitsakis; Konstantinos E Litinas
Synthesis of hydroxycoumarins and hydroxybenzo[f]- or [h]coumarins as lipid peroxidation inhibitors.
Bioorganic & medicinal chemistry letters 2009;19(4):1139-42.
2009: Anna-Maria Katsori; Dimitra Hadjipavlou-Litina
Chalcones in cancer: understanding their role in terms of QSAR.
Current medicinal chemistry 2009;16(9):1062-81.
2008: Eleni Pontiki; Dimitra Hadjipavlou-Litina; A Th Chaviara
Evaluation of anti-inflammatory and antioxidant activities of copper (II) Schiff mono-base and copper(II) Schiff base coordination compounds of dien with heterocyclic aldehydes and 2-amino-5-methyl-thiazole.
Journal of enzyme inhibition and medicinal chemistry 2008;23(6):1011-7.
2008: Victoria Magrioti; George Naxakis; Dimitra Hadjipavlou-Litina; Alexandros Makriyannis; George Kokotos
A novel monoacylglycerol lipase inhibitor with analgesic and anti-inflammatory activity.
Bioorganic & medicinal chemistry letters 2008;18(20):5424-7.
2008: Christos A Kontogiorgis; M Mantzanidou; Dimitra Hadjipavlou-Litina
Chalcones and their potential role in inflammation.
Mini reviews in medicinal chemistry 2008;8(12):1224-42.
2008: A J Michael; Constantinos Alexopoulos; Eleni Pontiki; Dimitra Hadjipavlou-Litina; Ph Saratsis; Haralabos N Ververidis; Costas M Boscos
Quality and reactive oxygen species of extended canine semen after vitamin C supplementation.
Theriogenology 2008;70(5):827-35.
2008: Maria-Thiresia Charami; Diamanto Lazari; Anastasia Karioti; Helen Skaltsa; Dimitra Hadjipavlou-Litina; Christos Souleles
Antioxidant and antiinflammatory activities of Sideritis perfoliata subsp. perfoliata (Lamiaceae).
Phytotherapy research : PTR 2008;22(4):450-4.
2008: Christos A Kontogiorgis; Konstantinos E Litinas; Aristea Makri; Demetrios N Nicolaides; Anastasia Vronteli; Dimitra Hadjipavlou-Litina; Eleni Pontiki; Asimoula Siohou
Synthesis and biological evaluation of novel angular fused Pyrrolocoumarins.
Journal of enzyme inhibition and medicinal chemistry 2008;23(1):43-9.
2008: Dimitra Hadjipavlou-Litina
Histone deacetylase inhibitors.
Current pharmaceutical design 2008;14(6):504.
2008: Eleni Pontiki; Dimitra Hadjipavlou-Litina
Lipoxygenase inhibitors: a comparative QSAR study review and evaluation of new QSARs.
Medicinal research reviews 2008;28(1):39-117.
2007: Asunción Burguete; Eleni Pontiki; Dimitra Hadjipavlou-Litina; Raquel Villar; Esther Vicente; Beatriz Solano; Saioa Ancizu; Silvia Pérez-Silanes; Ignacio Aldana; Antonio Monge
Synthesis and anti-inflammatory/antioxidant activities of some new ring substituted 3-phenyl-1-(1,4-di-N-oxide quinoxalin-2-yl)-2-propen-1-one derivatives and of their 4,5-dihydro-(1H)-pyrazole analogues.
Bioorganic & medicinal chemistry letters 2007;17(23):6439-43.
2007: Christos A Kontogiorgis; Yanan Xu; Dimitra Hadjipavlou-Litina; Yuan Luo
Coumarin derivatives protection against ROS production in cellular models of Abeta toxicities.
Free radical research 2007;41(10):1168-80.
2007: Alia Michaelidou; Dimitra Hadjipavlou-Litina; I Matsini; E Tsitsogianni
Heterocyclic aryl(phenyl)acetic Acid and aryl acetohydroxamic acids as antiinflammatory -antioxidant agents and inhibitors of lipoxygenase and serine proteases.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2007;3(5):439-45.
2007: Eleni Pontiki; Dimitra Hadjipavlou-Litina
Synthesis and pharmacochemical evaluation of novel aryl-acetic acid inhibitors of lipoxygenase, antioxidants, and anti-inflammatory agents.
Bioorganic & medicinal chemistry 2007;15(17):5819-27.
2007: David A Six; Efrosini Barbayianni; Vassilios Loukas; Violetta Constantinou-Kokotou; Dimitra Hadjipavlou-Litina; Daren Stephens; Alan C Wong; Victoria Magrioti; Panagiota Moutevelis-Minakakis; Sharon F Baker; Edward A Dennis; George Kokotos
Structure-activity relationship of 2-oxoamide inhibition of group IVA cytosolic phospholipase A2 and group V secreted phospholipase A2.
Journal of medicinal chemistry 2007;50(17):4222-35.
2007: A Michael; Constantinos Alexopoulos; Eleni Pontiki; Dimitra Hadjipavlou-Litina; Ph Saratsis; Costas M Boscos
Effect of antioxidant supplementation on semen quality and reactive oxygen species of frozen-thawed canine spermatozoa.
Theriogenology 2007;68(2):204-12.
2007: Dimitra Hadjipavlou-Litina; Christos A Kontogiorgis; Eleni Pontiki; Marianna Dakanali; Antonia Akoumianaki; Haralambos E Katerinopoulos
Anti-inflammatory and antioxidant activity of coumarins designed as potential fluorescent zinc sensors.
Journal of enzyme inhibition and medicinal chemistry 2007;22(3):287-92.
2007: Anastasia Detsi; Dionysia Bouloumbasi; Kyriakos C Prousis; Maria Koufaki; Giorgos Athanasellis; Georgia Melagraki; Antreas Afantitis; Olga Igglessi-Markopoulou; Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Design and synthesis of novel quinolinone-3-aminoamides and their alpha-lipoic acid adducts as antioxidant and anti-inflammatory agents.
Journal of medicinal chemistry 2007;50(10):2450-8.
2007: Paraskevi Papaioannou; Diamanto Lazari; Anastasia Karioti; Christos Souleles; Jörg Heilmann; Dimitra Hadjipavlou-Litina; Helen Skaltsa
Phenolic compounds with antioxidant activity from Anthemis tinctoria L. (Asteraceae).
Zeitschrift für Naturforschung. C, Journal of biosciences 2007;62(5-6):326-30.
2007: D Panagoulis; Eleni Pontiki; E Skeva; Catherine P Raptopoulou; S Th Girousi; Dimitra Hadjipavlou-Litina; Catherine Dendrinou-Samara
Synthesis and pharmacochemical study of new Cu(II) complexes with thiophen-2-yl saturated and alpha,beta-unsaturated substituted carboxylic acids.
Journal of inorganic biochemistry 2007;101(4):623-34.
2007: Eleni Pontiki; Dimitra Hadjipavlou-Litina
Synthesis of phenyl-substituted amides with antioxidant and anti-inflammatory activity as novel lipoxygenase inhibitors.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2007;3(2):175-86.
2007: Catherine Koukoulitsa; Dimitra Hadjipavlou-Litina; George D Geromichalos; Helen Skaltsa
Inhibitory effect on soybean lipoxygenase and docking studies of some secondary metabolites, isolated from Origanum vulgare L. ssp. hirtum.
Journal of enzyme inhibition and medicinal chemistry 2007;22(1):99-104.
2007: Athina Geronikaki; Dimitra Hadjipavlou-Litina; Alla Zablotskaya; Izolda Segal
Organosilicon-containing thiazole derivatives as potential lipoxygenase inhibitors and anti-inflammatory agents.
Bioinorganic chemistry and applications 2007;():92145.
2007: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Nitric oxide release from coumarin-7-azomethine derivatives in the presence of thiol.
Arzneimittel-Forschung 2007;57(3):143-6.
2006: Anastasia Karioti; T Vrahimi-Hadjilouca; D Droushiotis; Ana Ciric; Dimitra Hadjipavlou-Litina; Helen Skaltsa
Analysis of the essential oil of Origanum dubium growing wild in Cyprus. Investigation of its antioxidant capacity and antimicrobial activity.
Planta medica 2006;72(14):1330-4.
2006: Catherine Koukoulitsa; Chariklia Zika; Dimitra Hadjipavlou-Litina; Vassilis J Demopoulos; Helen Skaltsa
Inhibitory effect of polar oregano extracts on aldose reductase and soybean lipoxygenase in vitro.
Phytotherapy research : PTR 2006;20(7):605-6.
2006: Eleni Pontiki; Dimitra Hadjipavlou-Litina
Antioxidant and anti-inflammatory activity of aryl-acetic and hydroxamic acids as novel lipoxygenase inhibitors.
Medicinal chemistry (Shāriqah (United Arab Emirates)) 2006;2(3):251-64.
2006: Eleni Pontiki; Dimitra Hadjipavlou-Litina; A Th Chaviara; CA Bolos
Evaluation of anti-inflammatory and antioxidant activities of mixed-ligand Cu(II) complexes of dien and its Schiff dibases with heterocyclic aldehydes and 2-amino-2-thiazoline.
Bioorganic & medicinal chemistry letters 2006;16(8):2234-7.
2006: Christos A Kontogiorgis; Kyriakos Savvoglou; Dimitra Hadjipavlou-Litina
Antiinflammatory and antioxidant evaluation of novel coumarin derivatives.
Journal of enzyme inhibition and medicinal chemistry 2006;21(1):21-9.
2006: Tony L Yaksh; George Kokotos; Camilla I Svensson; Daren Stephens; Christoforos G Kokotos; Bethany Fitzsimmons; Dimitra Hadjipavlou-Litina; Xiao-Ying Hua; Edward A Dennis
Systemic and intrathecal effects of a novel series of phospholipase A2 inhibitors on hyperalgesia and spinal prostaglandin E2 release.
The Journal of pharmacology and experimental therapeutics 2006;316(1):466-75.
2005: A Th Chaviara; P C Christidis; Athanasios Papageorgiou; E Chrysogelou; Dimitra Hadjipavlou-Litina; CA Bolos
In vivo anticancer, anti-inflammatory, and toxicity studies of mixed-ligand Cu(II) complexes of dien and its Schiff dibases with heterocyclic aldehydes and 2-amino-2-thiazoline. Crystal structure of [Cu(dien)(Br)(2a-2tzn)](Br)(H(2)O).
Journal of inorganic biochemistry 2005;99(11):2102-9.
2005: Christina Papadopoulou; Athina Geronikaki; Dimitra Hadjipavlou-Litina
Synthesis and biological evaluation of new thiazolyl/benzothiazolyl-amides, derivatives of 4-phenyl-piperazine.
Farmaco (Società chimica italiana : 1989) 2005;60(11-12):969-73.
2005: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Synthesis and antiinflammatory activity of coumarin derivatives.
Journal of medicinal chemistry 2005;48(20):6400-8.
2005: Demetris Vrakas; Dimitra Hadjipavlou-Litina; Anna Tsantili-Kakoulidou
Retention of substituted coumarins using immobilized artificial membrane (IAM) chromatography: a comparative study with n-octanol partitioning and reversed-phase HPLC and TLC.
Journal of pharmaceutical and biomedical analysis 2005;39(5):908-13.
2005: Alia Michaelidou; Dimitra Hadjipavlou-Litina
Nonsteroidal anti-inflammatory drugs (NSAIDs): a comparative QSAR study.
Chemical reviews 2005;105(9):3235-71.
2005: A C Kontogiorgis; A E Pontiki; Dimitra Hadjipavlou-Litina
A review on quantitative structure-activity relationships (QSARs) of natural and synthetic antioxidants compounds.
Mini reviews in medicinal chemistry 2005;5(6):563-74.
2005: Antonio Varnavas; Lucia Lassiani; Valentina Valenta; Laura Mennuni; Francesco Makovec; Dimitra Hadjipavlou-Litina
Anthranilic acid based CCK1 receptor antagonists: preliminary investigation on their second "touch point".
European journal of medicinal chemistry 2005;40(6):563-81.
2005: Eleni Pontiki; Dimitra Hadjipavlou-Litina; Athanassios M Demertzis; Ioannis Hadjidakis; Dimitra Kovala-Demertzi
Quantitative structure activity relationships (QSAR) of substituded (S)-phenylpiperidines as preferential dopamine autoreceptor antagonists.
Journal of enzyme inhibition and medicinal chemistry 2005;20(1):5-12.
2005: Christos A Kontogiorgis; P Papaioannou; Dimitra Hadjipavlou-Litina
Matrix metalloproteinase inhibitors: a review on pharmacophore mapping and (Q)SARs results.
Current medicinal chemistry 2005;12(3):339-55.
2004: Anastasia Karioti; Dimitra Hadjipavlou-Litina; Merlin L K Mensah; Theophilus C Fleischer; Helen Skaltsa
Composition and antioxidant activity of the essential oils of Xylopia aethiopica (Dun) A. Rich. (Annonaceae) leaves, stem bark, root bark, and fresh and dried fruits, growing in Ghana.
Journal of agricultural and food chemistry 2004;52(26):8094-8.
2004: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Current trends in quantitative structure activity relationships on FXa inhibitors: evaluation and comparative analysis.
Medicinal research reviews 2004;24(6):687-747.
2004: Dimitra Hadjipavlou-Litina; Rajni Garg; Corwin Hansch
Comparative quantitative structure-activity relationship studies (QSAR) on non-benzodiazepine compounds binding to benzodiazepine receptor (BzR).
Chemical reviews 2004;104(9):3751-94.
2004: Demetris Vrakas; Dimitra Hadjipavlou-Litina; Anna Tsantili-Kakoulidou
Analysis of the interaction of substituted coumarins with the DPPH free radical by means of multivariate statistics.
The Journal of pharmacy and pharmacology 2004;56(9):1191-4.
2004: George Kokotos; David A Six; Vassilios Loukas; Timothy Smith; Violetta Constantinou-Kokotou; Dimitra Hadjipavlou-Litina; Stavroula Kotsovolou; Antonia Chiou; Christopher C Beltzner; Edward A Dennis
Inhibition of group IVA cytosolic phospholipase A2 by novel 2-oxoamides in vitro, in cells, and in vivo.
Journal of medicinal chemistry 2004;47(14):3615-28.
2004: Demetrios N Nicolaides; Daman R Gautam; Konstantinos E Litinas; Dimitra Hadjipavlou-Litina; Konstantina C Fylaktakidou
Synthesis and evaluation of the antioxidant and antiinflammatory activities of some benzo[l]khellactone derivatives and analogues.
European journal of medicinal chemistry 2004;39(4):323-32.
2004: Ioannis Leventis; Ioanna Andreadou; Apostolos Papalois; Ioannis Sfiniadakis; Vassilis G Gorgoulis; Dimitris P Korkolis; Dimitra Hadjipavlou-Litina; Panos N Kourounakis; Constantine I Fotiadis
A novel antioxidant non-steroidal anti-inflammatory agent protects rat liver against ischemia-reperfusion injury.
In vivo (Athens, Greece) 2004;18(2):161-9.
2004: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Synthesis and biological evaluation of novel coumarin derivatives with a 7-azomethine linkage.
Bioorganic & medicinal chemistry letters 2004;14(3):611-4.
2004: Konstantina C Fylaktakidou; Dimitra Hadjipavlou-Litina; Konstantinos E Litinas; Demetrios N Nicolaides
Natural and synthetic coumarin derivatives with anti-inflammatory/ antioxidant activities.
Current pharmaceutical design 2004;10(30):3813-33.
2004: Athina Geronikaki; Paola Vicini; Matteo Incerti; Dimitra Hadjipavlou-Litina
Thiazolyl and isothiazolyl azomethine derivatives with anti-inflammatory and antioxidant activities.
Arzneimittel-Forschung 2004;54(9):530-7.
2003: Alia Michaelidou; Dimitra Hadjipavlou-Litina
Anti-inflammatory, antioxidant and analgesic amides.
Journal of enzyme inhibition and medicinal chemistry 2003;18(6):537-44.
2003: Athina Geronikaki; Dimitra Hadjipavlou-Litina; Maria Amourgianou
Novel thiazolyl, thiazolinyl and benzothiazolyl Schiff bases as possible lipoxygenase's inhibitors and anti-inflammatory agents.
Farmaco (Società chimica italiana : 1989) 2003;58(7):489-95.
2003: Victoria Magrioti; Dimitra Hadjipavlou-Litina; Violetta Constantinou-Kokotou
Synthesis and In vivo anti-inflammatory activity of long-chain 2-amino-alcohols.
Bioorganic & medicinal chemistry letters 2003;13(3):375-7.
2003: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Biological evaluation of several coumarin derivatives designed as possible anti-inflammatory/antioxidant agents.
Journal of enzyme inhibition and medicinal chemistry 2003;18(1):63-9.
2003: Eleni Pontiki; Dimitra Hadjipavlou-Litina
Synthesis, antioxidant and antiinflammatory activity of novel aryla-cetic and aryl-hydroxamic acids.
Arzneimittel-Forschung 2003;53(11):780-5.
2002: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Current trends in QSAR on NO donors and inhibitors of nitric oxide synthase (NOS)*.
Medicinal research reviews 2002;22(4):385-418.
2002: Athina Geronikaki; Alexey A Lagunin; Vladimir Poroikov; Dmitrii A Filimonov; Dimitra Hadjipavlou-Litina; Paola Vicini
Computer aided prediction of biological activity spectra: evaluating versus known and predicting of new activities for thiazole derivatives.
SAR and QSAR in environmental research 2002;13(3-4):457-71.
2002: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Nitric oxide release from coumarin 4-carboxamidoximes in the presence of thiols.
Arzneimittel-Forschung 2002;52(3):205-10.
2002: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina
Non steroidal anti-inflammatory and anti-allergy agents.
Current medicinal chemistry 2002;9(1):89-98.
2001: Christos A Kontogiorgis; Dimitra Hadjipavlou-Litina; E Schulz
Antioxidant activity of DL omega-phenyl-amino acid octyl esters with anti-inflammatory activity. Correlation of the structure with lipophilicity.
Arzneimittel-Forschung 2001;51(6):485-8.
2000: Dimitra Hadjipavlou-Litina
New diaminoether coumarinic derivatives with anti-inflammatory activity.
Arzneimittel-Forschung 2000;50(7):631-5.
2000: Dimitra Hadjipavlou-Litina
Quantitative structure--activity relationship (QSAR) studies on non steroidal anti-inflammatory drugs (NSAIDs).
Current medicinal chemistry 2000;7(4):375-88.
2000: Athina Geronikaki; Dimitra Hadjipavlou-Litina; M Tzaki
Synthesis of some new thienyl and 1,3-thiazolyl-aminoketones with anti-inflammatory activity.
Arzneimittel-Forschung 2000;50(3):266-71.
1999: Jose Padron; VS Martin; Dimitra Hadjipavlou-Litina; Caterina Noula; Violetta Constantinou-Kokotou; GJ Peters; George Kokotos
Synthesis, in vitro cytotoxicity and in vivo anti-inflammatory activity of long chain 3-amino-1,2-diols.
Bioorganic & medicinal chemistry letters 1999;9(6):821-6.
1999: George Kokotos; Violetta Constantinou-Kokotou; Caterina Noula; Dimitra Hadjipavlou-Litina
Synthetic routes to lipidic diamines and amino alcohols: a class of potential antiinflammatory agents.
Lipids 1999;34(3):307-11.
1998: Dimitra Hadjipavlou-Litina; Athina Geronikaki
Thiazolyl and benzothiazolyl Schiff bases as novel possible lipoxygenase inhibitors and anti inflammatory agents. Synthesis and biological evaluation.
Drug design and discovery 1998;15(3):199-206.
1998: Athina Geronikaki; Dimitra Hadjipavlou-Litina
Synthesis of some new aroyl/aryloxy-2-amino-1,3-thiazole derivatives with anti-inflammatory activity.
Arzneimittel-Forschung 1998;48(3):263-5.
1998: Dimitra Hadjipavlou-Litina
Review, reevaluation, and new results in quantitative structure-activity studies of anticonvulsants.
Medicinal research reviews 1998;18(2):91-119.
1997: Dimitra Hadjipavlou-Litina; Athina Geronikaki
Effect of 2,4-disubstituted thiazol-5yl-aminoketones on inflammation. In vitro and in vivo biological studies: a structure-activity approach.
Research communications in molecular pathology and pharmacology 1997;96(3):307-18.
1997: Dimitra Hadjipavlou-Litina
1-[3-(Aryloxy) propyl]-diamines: a new class of non-steroidal basic antiinflammatory agents. Structure-activity studies: Part II.
Research communications in molecular pathology and pharmacology 1997;95(3):319-29.
1996: Athina Geronikaki; Dimitra Hadjipavlou-Litina
In vitro studies of some 2,4-disubstituted thiazolyl-aminoketones with anti-inflammatory activity. Correlation with lipophilicity and structural characteristics.
Arzneimittel-Forschung 1996;46(12):1134-7.
1996: Dimitra Hadjipavlou-Litina
QSAR studies of some sulphonamidobenzophenone oximes with antiviral activity.
The Journal of pharmacy and pharmacology 1996;48(12):1215-7.
1996: Dimitra Hadjipavlou-Litina; Athina Geronikaki
Anti-inflammatory activity of some novel 1-[3-(aroylo)] and one 1-[3-(aryloxy)]-propyl aminothiazole in correlation with structure and lipophilicity.
Arzneimittel-Forschung 1996;46(8):805-8.
1996: Dimitra Hadjipavlou-Litina
QSAR of thiosemicarbazones derived from formyl- and acyl-diazines designed as antiviral agents.
Die Pharmazie 1996;51(7):468-70.
1995: Dimitra Hadjipavlou-Litina
QSAR of N2-phenylguanidines as inhibitors of herpes simplex virus-1 thymidine kinase.
Die Pharmazie 1995;50(12):796-8.
1993: Athina Geronikaki; Dimitra Hadjipavlou-Litina
Lipophilicity and antiinflammatory activity of some 2-(aminoacetylamino)thiazole derivatives.
Die Pharmazie 1993;48(12):948-9.
1993: Dimitra Hadjipavlou-Litina; Athina Geronikaki; E Sotiropoulou
Antiinflammatory activity of aminoketone derivatives of 2,4-disubstituted thiazoles.
Research communications in chemical pathology and pharmacology 1993;79(3):355-62.