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Andrea Haegebarth

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Sylvia F Boj; Pierre Chambon; Edwin Cuppen; Yuval Dor; Cristina Fillat; Andrea Haegebarth; Pantelis Hatzis; Meritxell Huch; Anabel José; Vivian S W Li; Michal Mokry; Maaike van den Born; Johan H van Es; Peter Voshol; Hans Clevers
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.
Johan H van Es; Alexander van Oudenaarden; Sylvia F Boj; Andrea Haegebarth; Shalev Itzkovitz; Bon-Kyoung Koo; Jeroen Korving; Pekka Kujala; Sylvie Robine; Maaike van den Born; Hans Clevers
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.
Jessica Gierut; Andrea Haegebarth; Susan Ball-Kell; Wenjun Bie; Robert E Carroll; Yu Zheng; Angela L Tyner
Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane.

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All Publications

2012: Sylvia F Boj; Pierre Chambon; Edwin Cuppen; Yuval Dor; Cristina Fillat; Andrea Haegebarth; Pantelis Hatzis; Meritxell Huch; Anabel José; Vivian S W Li; Michal Mokry; Maaike van den Born; Johan H van Es; Peter Voshol; Hans Clevers
Diabetes risk gene and Wnt effector Tcf7l2/TCF4 controls hepatic response to perinatal and adult metabolic demand.
Cell 2012;151(7):1595-607.
2012: Johan H van Es; Alexander van Oudenaarden; Sylvia F Boj; Andrea Haegebarth; Shalev Itzkovitz; Bon-Kyoung Koo; Jeroen Korving; Pekka Kujala; Sylvie Robine; Maaike van den Born; Hans Clevers
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.
Molecular and cellular biology 2012;32(10):1918-27.
2011: Jessica Gierut; Andrea Haegebarth; Susan Ball-Kell; Wenjun Bie; Robert E Carroll; Yu Zheng; Angela L Tyner
Disruption of the mouse protein tyrosine kinase 6 gene prevents STAT3 activation and confers resistance to azoxymethane.
Gastroenterology 2011;141(4):1371-80, 1380.e1-2.
2011: Wim de Lau; Daniele Guardavaccaro; Andrea Haegebarth; Albert J R Heck; Bon-Kyoung Koo; Pekka Kujala; Vivian S W Li; Teck Y Low; shabaz mohammed; Yasuaki Mohri; Katsuhiko Nishimori; Peter J Peters; Richard B M Schasfoort; Daniel E Stange; Hans Teunissen; Marc van de Wetering; Johan E van Es; Nick Barker; Hans Clevers
Lgr5 homologues associate with Wnt receptors and mediate R-spondin signalling.
Nature 2011;476(7360):293-7.
2010: Daniele V F Tauriello; Andrea Haegebarth; Ineke Kuper; Mariola J Edelmann; Marre Henraat; Marijke R Canninga-Van Dijk; Benedikt M Kessler; Hans Clevers; Madelon M Maurice
Loss of the tumor suppressor CYLD enhances Wnt/beta-catenin signaling through K63-linked ubiquitination of Dvl.
Molecular cell 2010;37(5):607-19.
2010: Hugo J Snippert; Andrea Haegebarth; Maria Kasper; Viljar Jaks; Johan H van Es; Nick Barker; Marc van de Wetering; Maaike van den Born; Harry Begthel; Robert G Vries; Daniel E Stange; Rune Toftgård; Hans Clevers
Lgr6 marks stem cells in the hair follicle that generate all cell lineages of the skin.
Science (New York, N.Y.) 2010;327(5971):1385-9.
2009: Andrea Haegebarth; Ansu O Perekatt; Wenjun Bie; Jessica J Gierut; Angela L Tyner
Induction of protein tyrosine kinase 6 in mouse intestinal crypt epithelial cells promotes DNA damage-induced apoptosis.
Gastroenterology 2009;137(3):945-54.
2009: Laurens G van der Flier; Andrea Haegebarth; Daniel E Stange; Marc van de Wetering; Hans Clevers
OLFM4 is a robust marker for stem cells in human intestine and marks a subset of colorectal cancer cells.
Gastroenterology 2009;137(1):15-7.
2009: Laurens G van der Flier; Marielle E van Gijn; Pantelis Hatzis; Pekka Kujala; Andrea Haegebarth; Daniel E Stange; Harry Begthel; Maaike van den Born; Victor Guryev; Irma Oving; Johan H van Es; Nick Barker; Peter J Peters; Marc van de Wetering; Hans Clevers
Transcription factor achaete scute-like 2 controls intestinal stem cell fate.
Cell 2009;136(5):903-12.
2009: Andrea Haegebarth; Hans Clevers
Wnt signaling, lgr5, and stem cells in the intestine and skin.
The American journal of pathology 2009;174(3):715-21.
2007: Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Nature 2007;449(7165):1003-7.
2007: Laurens G Van der Flier; Jacob Sabates Bellver; Irma Oving; Andrea Haegebarth; Mariagrazia De Palo; Marcello Anti; Marielle E van Gijn; Saskia Suijkerbuijk; Marc van de Wetering; Giancarlo Marra; Hans Clevers
The Intestinal Wnt/TCF Signature.
Gastroenterology 2007;132(2):628-32.
2006: Andrea Haegebarth; Wenjun Bie; Ruyan Yang; Susan E Crawford; Valeri Vasioukhin; Elaine Fuchs; Angela L Tyner
Protein tyrosine kinase 6 negatively regulates growth and promotes enterocyte differentiation in the small intestine.
Molecular and cellular biology 2006;26(13):4949-57.
2006: Ruyan Yang; Wenjun Bie; Andrea Haegebarth; Angela L Tyner
Differential regulation of D-type cyclins in the mouse intestine.
Cell cycle (Georgetown, Tex.) 2006;5(2):180-3.
2005: Andrea Haegebarth; Rafael Nunez; Angela L Tyner
The intracellular tyrosine kinase Brk sensitizes non-transformed cells to inducers of apoptosis.
Cell cycle (Georgetown, Tex.) 2005;4(9):1239-46.
2004: Andrea Haegebarth; Darien Heap; Wenjun Bie; Jason J Derry; Stéphane Richard; Angela L Tyner
The nuclear tyrosine kinase BRK/Sik phosphorylates and inhibits the RNA-binding activities of the Sam68-like mammalian proteins SLM-1 and SLM-2.
The Journal of biological chemistry 2004;279(52):54398-404.
2004: Senthil K Radhakrishnan; Claudine S Feliciano; Feridoon Najmabadi; Andrea Haegebarth; Eugene S Kandel; Angela L Tyner; Andrei L Gartel
Constitutive expression of E2F-1 leads to p21-dependent cell cycle arrest in S phase of the cell cycle.
Oncogene 2004;23(23):4173-6.