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Judith Haendeler

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Tim-Christian Zschauer; Joachim Altschmied; Shouji Matsushima; Junichi Sadoshima; Dan Shao; Judith Haendeler
Interacting with thioredoxin-1--disease or no disease?
Nicole Büchner; Niloofar Ale-Agha; Joachim Altschmied; Sascha Jakob; Kerstin Kunze; Ulrich Sydlik; Klaus Unfried; Judith Haendeler
Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.
Judith Haendeler; Margarete Lukosz; Klaus Unfried; Anna Eckers; Joachim Altschmied
Endothelial NADPH oxidase 2: when does it matter in atherosclerosis?

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2013: Tim-Christian Zschauer; Joachim Altschmied; Shouji Matsushima; Junichi Sadoshima; Dan Shao; Judith Haendeler
Interacting with thioredoxin-1--disease or no disease?
Antioxidants & redox signaling 2013;18(9):1053-62.
2013: Nicole Büchner; Niloofar Ale-Agha; Joachim Altschmied; Sascha Jakob; Kerstin Kunze; Ulrich Sydlik; Klaus Unfried; Judith Haendeler
Unhealthy diet and ultrafine carbon black particles induce senescence and disease associated phenotypic changes.
Experimental gerontology 2013;48(1):8-16.
2012: Judith Haendeler; Margarete Lukosz; Klaus Unfried; Anna Eckers; Joachim Altschmied
Endothelial NADPH oxidase 2: when does it matter in atherosclerosis?
Cardiovascular research 2012;94(1):1-2.
2012: Dan Shao; Christopher D Brady; Philip Eaton; Judith Haendeler; Shin-ichi Oka; Junichi Sadoshima
Redox modification of cell signaling in the cardiovascular system.
Journal of molecular and cellular cardiology 2012;52(3):550-8.
2012: Henrike Peuschel; Daniel Stöckmann; Ulrich Sydlik; Christiane Bieschke; Ingo Felsner; Marijan Gotić; Susanne Grether-Beck; Judith Haendeler; Sascha Jakob; Matthias Kroker; Jean Krutmann; Klaus Unfried
Carbon nanoparticles induce ceramide- and lipid raft-dependent signalling in lung epithelial cells: a target for a preventive strategy against environmentally-induced lung inflammation.
Particle and fibre toxicology 2012;9():48.
2011: Margarete Lukosz; Arne Mlynek; Joachim Altschmied; Philip Czypiorski; Judith Haendeler
The transcription factor Grainyhead like 3 (GRHL3) affects endothelial cell apoptosis and migration in a NO-dependent manner.
Biochemical and biophysical research communications 2011;412(4):648-53.
2011: Christian Werner; Christoph Gensch; Janine Pöss; Judith Haendeler; Michael Böhm; Ulrich Laufs
Pioglitazone activates aortic telomerase and prevents stress-induced endothelial apoptosis.
Atherosclerosis 2011;216(1):23-34.
2011: Tim-Christian Zschauer; Kerstin Kunze; Sascha Jakob; Judith Haendeler; Joachim Altschmied
Oxidative stress-induced degradation of thioredoxin-1 and apoptosis is inhibited by thioredoxin-1-actin interaction in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2011;31(3):650-6.
2010: Henrike Peuschel; Ulrich Sydlik; Judith Haendeler; Nicole Büchner; Daniel Stöckmann; Matthias Kroker; Ragnhild Wirth; Winfried Brock; Klaus Unfried
c-Src-mediated activation of Erk1/2 is a reaction of epithelial cells to carbon nanoparticle treatment and may be a target for a molecular preventive strategy.
Biological chemistry 2010;391(11):1327-32.
2010: Nicole Büchner; Joachim Altschmied; Sascha Jakob; Gabriele Saretzki; Judith Haendeler
Well-known signaling proteins exert new functions in the nucleus and mitochondria.
Antioxidants & redox signaling 2010;13(4):551-8.
2010: Nicole Büchner; Tim-Christian Zschauer; Margarete Lukosz; Joachim Altschmied; Judith Haendeler
Downregulation of mitochondrial telomerase reverse transcriptase induced by H2O2 is Src kinase dependent.
Experimental gerontology 2010;45(7-8):558-62.
2010: Florian H Seeger; Daniel Sedding; Alexander C Langheinrich; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Inhibition of the p38 MAP kinase in vivo improves number and functional activity of vasculogenic cells and reduces atherosclerotic disease progression.
Basic research in cardiology 2010;105(3):389-97.
2010: Margarete Lukosz; Sascha Jakob; Nicole Büchner; Tim-Christian Zschauer; Joachim Altschmied; Judith Haendeler
Nuclear redox signaling.
Antioxidants & redox signaling 2010;12(6):713-42.
2009: Christian Werner; Tobias Fürster; Thomas Widmann; Janine Pöss; Cristiana Roggia; Milad Hanhoun; Jürgen Scharhag; Nicole Büchner; Tim Meyer; Wilfried Kindermann; Judith Haendeler; Michael Böhm; Ulrich Laufs
Physical exercise prevents cellular senescence in circulating leukocytes and in the vessel wall.
Circulation 2009;120(24):2438-47.
2009: Mentor Sopjani; Michael Föller; Judith Haendeler; Friedrich Götz; Florian Lang
Silver ion-induced suicidal erythrocyte death.
Journal of applied toxicology : JAT 2009;29(6):531-6.
2009: Sascha Jakob; Joachim Altschmied; Judith Haendeler
"Shping 2" different cellular localizations - a potential new player in aging processes.
Aging 2009;1(7):664-8.
2009: Joachim Altschmied; Judith Haendeler
Thioredoxin-1 and endothelial cell aging: role in cardiovascular diseases.
Antioxidants & redox signaling 2009;11(7):1733-40.
2009: Judith Haendeler; Stefan Dröse; Nicole Büchner; Sascha Jakob; Joachim Altschmied; Christine Goy; Ioakim Spyridopoulos; Andreas M Zeiher; Ulrich Brandt; Stefanie Dimmeler
Mitochondrial telomerase reverse transcriptase binds to and protects mitochondrial DNA and function from damage.
Arteriosclerosis, thrombosis, and vascular biology 2009;29(6):929-35.
2009: Masamichi Koyanagi; Masayoshi Iwasaki; Judith Haendeler; Michael Leitges; Andreas M Zeiher; Stefanie Dimmeler
Wnt5a increases cardiac gene expressions of cultured human circulating progenitor cells via a PKC delta activation.
PloS one 2009;4(6):e5765.
2009: Florian Hartmut Seeger; Linping Chen; Ioakim Spyridopoulos; Joachim Altschmied; Alexandra Aicher; Judith Haendeler
Downregulation of ETS rescues diabetes-induced reduction of endothelial progenitor cells.
PloS one 2009;4(2):e4529.
2008: Sascha Jakob; Peter Schroeder; Margarete Lukosz; Nicole Büchner; Ioakim Spyridopoulos; Joachim Altschmied; Judith Haendeler
Nuclear protein tyrosine phosphatase Shp-2 is one important negative regulator of nuclear export of telomerase reverse transcriptase.
The Journal of biological chemistry 2008;283(48):33155-61.
2008: Francisca Guardiola-Serrano; Judith Haendeler; Margarete Lukosz; Karsten Sturm; Harald von Melchner; Joachim Altschmied
Gene trapping identifies a putative tumor suppressor and a new inducer of cell migration.
Biochemical and biophysical research communications 2008;376(4):748-52.
2008: Ioakim Spyridopoulos; Stephan Fichtlscherer; Rüdiger Popp; Stefan W Toennes; Beate Fisslthaler; Thomas Trepels; Alma Zernecke; Elisa A Liehn; Christian Weber; Andreas M Zeiher; Stefanie Dimmeler; Judith Haendeler
Caffeine enhances endothelial repair by an AMPK-dependent mechanism.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(11):1967-74.
2008: Joachim Altschmied; Judith Haendeler
A new kid on the block: PKD1: a promising target for antiangiogenic therapy?
Arteriosclerosis, thrombosis, and vascular biology 2008;28(10):1689-90.
2008: Christian Werner; Milad Hanhoun; Thomas Widmann; Andrey Kazakov; Alexander Semenov; Janine Pöss; Johann Bauersachs; Thomas Thum; Michael Pfreundschuh; Patrick Müller; Judith Haendeler; Michael Böhm; Ulrich Laufs
Effects of physical exercise on myocardial telomere-regulating proteins, survival pathways, and apoptosis.
Journal of the American College of Cardiology 2008;52(6):470-82.
2008: Peter Schroeder; Judith Haendeler; Jean Krutmann
The role of near infrared radiation in photoaging of the skin.
Experimental gerontology 2008;43(7):629-32.
2008: Nicole Buechner; Peter Schroeder; Sascha Jakob; Kerstin Kunze; Tanja Maresch; Christian Calles; Jean Krutmann; Judith Haendeler
Changes of MMP-1 and collagen type Ialpha1 by UVA, UVB and IRA are differentially regulated by Trx-1.
Experimental gerontology 2008;43(7):633-7.
2008: Ioakim Spyridopoulos; Young Erben; Tim H Brummendorf; Judith Haendeler; Klaus Dietz; Florian H Seeger; Christine K Kissel; Hans Martin; Jedrzej Hoffmann; Birgit Assmus; Andreas M Zeiher; Stefanie Dimmeler
Telomere gap between granulocytes and lymphocytes is a determinant for hematopoetic progenitor cell impairment in patients with previous myocardial infarction.
Arteriosclerosis, thrombosis, and vascular biology 2008;28(5):968-74.
2008: Jan P Nicolay; Gerd Liebig; Olivier M Niemoeller; Saisudha Koka; Mehrdad Ghashghaeinia; Thomas Wieder; Judith Haendeler; Rudi Busse; Florian Lang
Inhibition of suicidal erythrocyte death by nitric oxide.
Pflügers Archiv : European journal of physiology 2008;456(2):293-305.
2008: Judith Haendeler; Lars-Oliver Klotz
Highlight: oxidative stress and senescence.
Biological chemistry 2008;389(3):201.
2007: Ingrid Fleming; Alexandra Rueben; Rüdiger Popp; Beate Fisslthaler; Susanne Schrodt; Anna Sander; Judith Haendeler; John R Falck; Christophe Morisseau; Bruce D Hammock; Rudi Busse
Epoxyeicosatrienoic acids regulate Trp channel dependent Ca2+ signaling and hyperpolarization in endothelial cells.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(12):2612-8.
2007: Peter Schroeder; Ruediger Popp; Barbara Wiegand; Joachim Altschmied; Judith Haendeler
Nuclear redox-signaling is essential for apoptosis inhibition in endothelial cells--important role for nuclear thioredoxin-1.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(11):2325-31.
2007: Michael Potente; Laleh Ghaeni; danila baldessari; Raul Mostoslavsky; Lothar Rossig; Franck Dequiedt; Judith Haendeler; Marina Mione; Elisabetta Dejana; Frederick W Alt; Andreas M Zeiher; Stefanie Dimmeler
SIRT1 controls endothelial angiogenic functions during vascular growth.
Genes & development 2007;21(20):2644-58.
2007: Daniel G Sedding; Judith Haendeler
Do we age on Sirt1 expression?
Circulation research 2007;100(10):1396-8.
2007: Dirk H Walter; Ulrich Rochwalsky; Johannes Reinhold; Florian H Seeger; Alexandra Aicher; Carmen Urbich; Ioakim Spyridopoulos; Jerold Chun; Volker Brinkmann; Petra Keul; Bodo Levkau; Andreas M Zeiher; Stefanie Dimmeler; Judith Haendeler
Sphingosine-1-phosphate stimulates the functional capacity of progenitor cells by activation of the CXCR4-dependent signaling pathway via the S1P3 receptor.
Arteriosclerosis, thrombosis, and vascular biology 2007;27(2):275-82.
2006: Jörg Honold; Ralf Lehmann; Christopher Heeschen; Dirk H Walter; Birgit Assmus; Ken-ichiro Sasaki; Hans Martin; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Effects of granulocyte colony simulating factor on functional activities of endothelial progenitor cells in patients with chronic ischemic heart disease.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(10):2238-43.
2006: Judith Haendeler
Thioredoxin-1 and posttranslational modifications.
Antioxidants & redox signaling 2006;8(9-10):1723-8.
2006: Judith Haendeler; Stefanie Dimmeler
Inseparably tied: functional and antioxidative capacity of endothelial progenitor cells.
Circulation research 2006;98(2):157-8.
2005: Judith Haendeler; Rüdiger Popp; Christine Goy; Verena Tischler; Andreas M Zeiher; Stefanie Dimmeler
Cathepsin D and H2O2 stimulate degradation of thioredoxin-1: implication for endothelial cell apoptosis.
The Journal of biological chemistry 2005;280(52):42945-51.
2005: Tanja Keiper; Nadia Al-Fakhri; Emmanouil Chavakis; Athanasios N Athanasopoulos; Berend Isermann; Stefanie Herzog; Rainer Saffrich; Karin Hersemeyer; Rainer M Bohle; Judith Haendeler; Klaus T Preissner; Sentot Santoso; Triantafyllos Chavakis
The role of junctional adhesion molecule-C (JAM-C) in oxidized LDL-mediated leukocyte recruitment.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(14):2078-80.
2005: Dirk H Walter; Judith Haendeler; Johannes Reinhold; Ulrich Rochwalsky; Florian H Seeger; Jörg Honold; Jörg Hoffmann; Carmen Urbich; Ralf Lehmann; Fernando Arenzana-Seisdesdos; Alexandra Aicher; Christopher Heeschen; Stephan Fichtlscherer; Andreas M Zeiher; Stefanie Dimmeler
Impaired CXCR4 signaling contributes to the reduced neovascularization capacity of endothelial progenitor cells from patients with coronary artery disease.
Circulation research 2005;97(11):1142-51.
2005: Masamichi Koyanagi; Carmen Urbich; Emmanouil Chavakis; Jörg Hoffmann; Stefan Rupp; Cornel Badorff; Andreas M Zeiher; Anna Starzinski-Powitz; Judith Haendeler; Stefanie Dimmeler
Differentiation of circulating endothelial progenitor cells to a cardiomyogenic phenotype depends on E-cadherin.
FEBS letters 2005;579(27):6060-6.
2005: Masamichi Koyanagi; Ralf P Brandes; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Cell-to-cell connection of endothelial progenitor cells with cardiac myocytes by nanotubes: a novel mechanism for cell fate changes?
Circulation research 2005;96(10):1039-41.
2005: Masamichi Koyanagi; Judith Haendeler; Cornel Badorff; Ralf P Brandes; Jörg Hoffmann; Petra Pandur; Andreas M Zeiher; Michael Kühl; Stefanie Dimmeler
Non-canonical Wnt signaling enhances differentiation of human circulating progenitor cells to cardiomyogenic cells.
The Journal of biological chemistry 2005;280(17):16838-42.
2005: Florian H Seeger; Judith Haendeler; Dirk H Walter; Ulrich Rochwalsky; Johannes Reinhold; Carmen Urbich; Lothar Rössig; Anne Corbaz; Yolande Chvatchko; Andreas M Zeiher; Stefanie Dimmeler
p38 mitogen-activated protein kinase downregulates endothelial progenitor cells.
Circulation 2005;111(9):1184-91.
2004: Judith Haendeler; Verena Tischler; Jörg Hoffmann; Andreas M Zeiher; Stefanie Dimmeler
Low doses of reactive oxygen species protect endothelial cells from apoptosis by increasing thioredoxin-1 expression.
FEBS letters 2004;577(3):427-33.
2004: Ioakim Spyridopoulos; Judith Haendeler; Carmen Urbich; Tim H Brummendorf; Hidemasa Oh; Michael D Schneider; Andreas M Zeiher; Stefanie Dimmeler
Statins enhance migratory capacity by upregulation of the telomere repeat-binding factor TRF2 in endothelial progenitor cells.
Circulation 2004;110(19):3136-42.
2004: Matthew G Melaragno; Megan E Cavet; Chen Yan; Lung-Kuo Tai; Zheng-Gen Jin; Judith Haendeler; Bradford C Berk
Gas6 inhibits apoptosis in vascular smooth muscle: role of Axl kinase and Akt.
Journal of molecular and cellular cardiology 2004;37(4):881-7.
2004: Judith Haendeler; Jörg Hoffmann; Andreas M Zeiher; Stefanie Dimmeler
Antioxidant effects of statins via S-nitrosylation and activation of thioredoxin in endothelial cells: a novel vasculoprotective function of statins.
Circulation 2004;110(7):856-61.
2004: Geerten P van Nieuw Amerongen; Kanchana Natarajan; Guoyong Yin; Ryan J Hoefen; Masaki Osawa; Judith Haendeler; A J Ridley; K Fujiwara; Victor W M van Hinsbergh; Bradford C Berk
GIT1 mediates thrombin signaling in endothelial cells: role in turnover of RhoA-type focal adhesions.
Circulation research 2004;94(8):1041-9.
2004: Judith Haendeler; Jörg Hoffmann; J Florian Diehl; Mariuca Vasa; Ioakim Spyridopoulos; Andreas M Zeiher; Stefanie Dimmeler
Antioxidants inhibit nuclear export of telomerase reverse transcriptase and delay replicative senescence of endothelial cells.
Circulation research 2004;94(6):768-75.
2004: Thomas Brühl; Christopher Heeschen; Alexandra Aicher; Amir S Jadidi; Judith Haendeler; Jörg Hoffmann; Michael D Schneider; Andreas M Zeiher; Stefanie Dimmeler; Lothar Rössig
p21Cip1 levels differentially regulate turnover of mature endothelial cells, endothelial progenitor cells, and in vivo neovascularization.
Circulation research 2004;94(5):686-92.
2004: Guoyong Yin; Judith Haendeler; Chen Yan; Bradford C Berk
GIT1 functions as a scaffold for MEK1-extracellular signal-regulated kinase 1 and 2 activation by angiotensin II and epidermal growth factor.
Molecular and cellular biology 2004;24(2):875-85.
2003: Judith Haendeler; Guoyong Yin; Yukihiro Hojo; Yuji Saito; Matthew G Melaragno; Chen Yan; Virendra K Sharma; Manfred Heller; Ruedi Aebersold; Bradford C Berk
GIT1 mediates Src-dependent activation of phospholipase Cgamma by angiotensin II and epidermal growth factor.
The Journal of biological chemistry 2003;278(50):49936-44.
2003: Hideyuki Yamawaki; Judith Haendeler; Bradford C Berk
Thioredoxin: a key regulator of cardiovascular homeostasis.
Circulation research 2003;93(11):1029-33.
2003: Jörg Hoffmann; Stefanie Dimmeler; Judith Haendeler
Shear stress increases the amount of S-nitrosylated molecules in endothelial cells: important role for signal transduction.
FEBS letters 2003;551(1-3):153-8.
2003: Judith Haendeler; Jörg Hoffmann; Ralf P Brandes; Andreas M Zeiher; Stefanie Dimmeler
Hydrogen peroxide triggers nuclear export of telomerase reverse transcriptase via Src kinase family-dependent phosphorylation of tyrosine 707.
Molecular and cellular biology 2003;23(13):4598-610.
2003: Birgit Assmus; Carmen Urbich; Alexandra Aicher; Wolf-Karsten Hofmann; Judith Haendeler; Lothar Rössig; Ioakim Spyridopoulos; Andreas M Zeiher; Stefanie Dimmeler
HMG-CoA reductase inhibitors reduce senescence and increase proliferation of endothelial progenitor cells via regulation of cell cycle regulatory genes.
Circulation research 2003;92(9):1049-55.
2003: Judith Haendeler; Jörg Hoffmann; Sandy Rahman; Andreas M Zeiher; Stefanie Dimmeler
Regulation of telomerase activity and anti-apoptotic function by protein-protein interaction and phosphorylation.
FEBS letters 2003;536(1-3):180-6.
2002: Yukihiro Hojo; Yuji Saito; Tatsuo Tanimoto; Ryan J Hoefen; Christopher P Baines; Kei Yamamoto; Judith Haendeler; Reto Asmis; Bradford C Berk
Fluid shear stress attenuates hydrogen peroxide-induced c-Jun NH2-terminal kinase activation via a glutathione reductase-mediated mechanism.
Circulation research 2002;91(8):712-8.
2002: Stefanie Dimmeler; Judith Haendeler; Andreas M Zeiher
Regulation of endothelial cell apoptosis in atherothrombosis.
Current opinion in lipidology 2002;13(5):531-6.
2002: Judith Haendeler; Jörg Hoffmann; Verena Tischler; Bradford C Berk; Andreas M Zeiher; Stefanie Dimmeler
Redox regulatory and anti-apoptotic functions of thioredoxin depend on S-nitrosylation at cysteine 69.
Nature cell biology 2002;4(10):743-9.
2002: Frank Jung; Judith Haendeler; Jörg Hoffmann; Agnes Reissner; Elisabeth Dernbach; Andreas M Zeiher; Stefanie Dimmeler
Hypoxic induction of the hypoxia-inducible factor is mediated via the adaptor protein Shc in endothelial cells.
Circulation research 2002;91(1):38-45.
2002: Ralf P Brandes; Francis J Miller; Stefani Beer; Judith Haendeler; Jörg Hoffmann; Tulinh Ha; Steven M Holland; Agnes Görlach; Rudi Busse
The vascular NADPH oxidase subunit p47phox is involved in redox-mediated gene expression.
Free radical biology & medicine 2002;32(11):1116-22.
2002: Carmen Urbich; Agnes Reissner; Emmanouil Chavakis; Elisabeth Dernbach; Judith Haendeler; Iingrid Fleming; Andreas M Zeiher; Marietta Kaszkin; Stefanie Dimmeler
Dephosphorylation of endothelial nitric oxide synthase contributes to the anti-angiogenic effects of endostatin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2002;16(7):706-8.
2002: Lothar Rössig; Corinna Hermann; Judith Haendeler; Birgit Assmus; Andreas M Zeiher; Stefanie Dimmeler
Angiotensin II-induced upregulation of MAP kinase phosphatase-3 mRNA levels mediates endothelial cell apoptosis.
Basic research in cardiology 2002;97(1):1-8.
2001: Jörg Hoffmann; Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
TNFalpha and oxLDL reduce protein S-nitrosylation in endothelial cells.
The Journal of biological chemistry 2001;276(44):41383-7.
2001: Jörg Hoffmann; Judith Haendeler; Alexandra Aicher; Lothar Rössig; Mariuca Vasa; Andreas M Zeiher; Stefanie Dimmeler
Aging enhances the sensitivity of endothelial cells toward apoptotic stimuli: important role of nitric oxide.
Circulation research 2001;89(8):709-15.
2001: Yuji Saito; Judith Haendeler; Y Hojo; K Yamamoto; Bradford C Berk
Receptor heterodimerization: essential mechanism for platelet-derived growth factor-induced epidermal growth factor receptor transactivation.
Molecular and cellular biology 2001;21(19):6387-94.
2000: Lothar Rössig; Judith Haendeler; Z Mallat; Bénédicte Hugel; Jean-Marie Freyssinet; A Tedgui; Stefanie Dimmeler; Andreas M Zeiher
Congestive heart failure induces endothelial cell apoptosis: protective role of carvedilol.
Journal of the American College of Cardiology 2000;36(7):2081-9.
2000: H Ou; Judith Haendeler; M R Aebly; Louise A Kelly; B C Cholewa; G Koike; AE Kwitek-Black; H J Jacob; Bradford C Berk; Joseph M Miano
Retinoic acid-induced tissue transglutaminase and apoptosis in vascular smooth muscle cells.
Circulation research 2000;87(10):881-7.
2000: Zheng-Gen Jin; Matthew G Melaragno; D F Liao; Chen Yan; Judith Haendeler; Y A Suh; David J. Lambeth; Bradford C Berk
Cyclophilin A is a secreted growth factor induced by oxidative stress.
Circulation research 2000;87(9):789-96.
2000: F Jung; Judith Haendeler; C Goebel; Andreas M Zeiher; Stefanie Dimmeler
Growth factor-induced phosphoinositide 3-OH kinase/Akt phosphorylation in smooth muscle cells: induction of cell proliferation and inhibition of cell death.
Cardiovascular research 2000;48(1):148-57.
2000: Lothar Rössig; Judith Haendeler; Corinna Hermann; P Malchow; Carmen Urbich; Andreas M Zeiher; Stefanie Dimmeler
Nitric oxide down-regulates MKP-3 mRNA levels: involvement in endothelial cell protection from apoptosis.
The Journal of biological chemistry 2000;275(33):25502-7.
2000: S Heeneman; Judith Haendeler; Yuji Saito; M Ishida; Bradford C Berk
Angiotensin II induces transactivation of two different populations of the platelet-derived growth factor beta receptor. Key role for the p66 adaptor protein Shc.
The Journal of biological chemistry 2000;275(21):15926-32.
2000: Masanori Yoshizumi; Jun-ichi Abe; Judith Haendeler; Qunhua Huang; Bradford C Berk
Src and Cas mediate JNK activation but not ERK1/2 and p38 kinases by reactive oxygen species.
The Journal of biological chemistry 2000;275(16):11706-12.
2000: Judith Haendeler; M Ishida; László Hunyady; Bradford C Berk
The third cytoplasmic loop of the angiotensin II type 1 receptor exerts differential effects on extracellular signal-regulated kinase (ERK1/ERK2) and apoptosis via Ras- and Rap1-dependent pathways.
Circulation research 2000;86(7):729-36.
2000: K Breitschopf; Judith Haendeler; P Malchow; Andreas M Zeiher; Stefanie Dimmeler
Posttranslational modification of Bcl-2 facilitates its proteasome-dependent degradation: molecular characterization of the involved signaling pathway.
Molecular and cellular biology 2000;20(5):1886-96.
2000: U Weiland; Judith Haendeler; Christian Ihling; Udo Albus; W Scholz; Hartmut Ruetten; Andreas M Zeiher; Stefanie Dimmeler
Inhibition of endogenous nitric oxide synthase potentiates ischemia-reperfusion-induced myocardial apoptosis via a caspase-3 dependent pathway.
Cardiovascular research 2000;45(3):671-8.
1999: Stefanie Dimmeler; K Breitschopf; Judith Haendeler; Andreas M Zeiher
Dephosphorylation targets Bcl-2 for ubiquitin-dependent degradation: a link between the apoptosome and the proteasome pathway.
The Journal of experimental medicine 1999;189(11):1815-22.
1999: Lothar Rössig; Birgit Fichtlscherer; K Breitschopf; Judith Haendeler; Andreas M Zeiher; Alexander Mülsch; Stefanie Dimmeler
Nitric oxide inhibits caspase-3 by S-nitrosation in vivo.
The Journal of biological chemistry 1999;274(11):6823-6.
1999: Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Nitric oxide and apoptosis.
Vitamins and hormones 1999;57():49-77.
1998: Dirk H Walter; Judith Haendeler; J Galle; Andreas M Zeiher; Stefanie Dimmeler
Cyclosporin A inhibits apoptosis of human endothelial cells by preventing release of cytochrome C from mitochondria.
Circulation 1998;98(12):1153-7.
1998: Stefanie Dimmeler; Birgit Assmus; Corinna Hermann; Judith Haendeler; Andreas M Zeiher
Fluid shear stress stimulates phosphorylation of Akt in human endothelial cells: involvement in suppression of apoptosis.
Circulation research 1998;83(3):334-41.
1998: Stefanie Dimmeler; Judith Haendeler; A Sause; Andreas M Zeiher
Nitric oxide inhibits APO-1/Fas-mediated cell death.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(5):415-22.
1997: Stefanie Dimmeler; V Rippmann; U Weiland; Judith Haendeler; Andreas M Zeiher
Angiotensin II induces apoptosis of human endothelial cells. Protective effect of nitric oxide.
Circulation research 1997;81(6):970-6.
1997: Judith Haendeler; U Weiland; Andreas M Zeiher; Stefanie Dimmeler
Effects of redox-related congeners of NO on apoptosis and caspase-3 activity.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(4):282-93.
1997: Stefanie Dimmeler; Judith Haendeler; J Galle; Andreas M Zeiher
Oxidized low-density lipoprotein induces apoptosis of human endothelial cells by activation of CPP32-like proteases. A mechanistic clue to the 'response to injury' hypothesis.
Circulation 1997;95(7):1760-3.
1997: Stefanie Dimmeler; Judith Haendeler; M Nehls; Andreas M Zeiher
Suppression of apoptosis by nitric oxide via inhibition of interleukin-1beta-converting enzyme (ICE)-like and cysteine protease protein (CPP)-32-like proteases.
The Journal of experimental medicine 1997;185(4):601-7.
1996: Judith Haendeler; Andreas M Zeiher; Stefanie Dimmeler
Vitamin C and E prevent lipopolysaccharide-induced apoptosis in human endothelial cells by modulation of Bcl-2 and Bax.
European journal of pharmacology 1996;317(2-3):407-11.
1996: Stefanie Dimmeler; Judith Haendeler; V Rippmann; M Nehls; Andreas M Zeiher
Shear stress inhibits apoptosis of human endothelial cells.
FEBS letters 1996;399(1-2):71-4.
1996: Judith Haendeler; U K Messmer; B Brüne; Edmund A M Neugebauer; Stefanie Dimmeler
Endotoxic shock leads to apoptosis in vivo and reduces Bcl-2.
Shock (Augusta, Ga.) 1996;6(6):405-9.