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Naoki Hagimoto

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Naoki Hamada; Kazuyoshi Kuwano; Mizuho Yamada; Naoki Hagimoto; Ken-ichi Hiasa; Kensuke Egashira; Nobutaka Nakashima; Takashige Maeyama; Michihiro Yoshimi; Yoichi Nakanishi
Anti-vascular endothelial growth factor gene therapy attenuates lung injury and fibrosis in mice.
Nobutaka Nakashima; Kazuyoshi Kuwano; Takashige Maeyama; Naoki Hagimoto; Michihiro Yoshimi; Naoki Hamada; Mizuho Yamada; Yoichi Nakanishi
The p53-Mdm2 association in epithelial cells in idiopathic pulmonary fibrosis and non-specific interstitial pneumonia.
Thomas R Martin; Naoki Hagimoto; Morio Nakamura; Gustavo Matute-Bello
Apoptosis and epithelial injury in the lungs.

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2005: Naoki Hamada; Kazuyoshi Kuwano; Mizuho Yamada; Naoki Hagimoto; Ken-ichi Hiasa; Kensuke Egashira; Nobutaka Nakashima; Takashige Maeyama; Michihiro Yoshimi; Yoichi Nakanishi
Anti-vascular endothelial growth factor gene therapy attenuates lung injury and fibrosis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(2):1224-31.
2005: Nobutaka Nakashima; Kazuyoshi Kuwano; Takashige Maeyama; Naoki Hagimoto; Michihiro Yoshimi; Naoki Hamada; Mizuho Yamada; Yoichi Nakanishi
The p53-Mdm2 association in epithelial cells in idiopathic pulmonary fibrosis and non-specific interstitial pneumonia.
Journal of clinical pathology 2005;58(6):583-9.
2005: Thomas R Martin; Naoki Hagimoto; Morio Nakamura; Gustavo Matute-Bello
Apoptosis and epithelial injury in the lungs.
Proceedings of the American Thoracic Society 2005;2(3):214-20.
2004: H Miyazaki; Kazuyoshi Kuwano; Koichiro Yoshida; Takashige Maeyama; Michihiro Yoshimi; Masaki Fujita; Naoki Hagimoto; R Yoshida; Yoichi Nakanishi
The perforin mediated apoptotic pathway in lung injury and fibrosis.
Journal of clinical pathology 2004;57(12):1292-8.
2004: K Kuwano; Naoki Hagimoto; Y Nakanishi
The role of apoptosis in pulmonary fibrosis.
Histology and histopathology 2004;19(3):867-81.
2004: Atsushi Moriwaki; Naoki Hagimoto; Hiroshi Wataya; Michihiro Yoshimi; Nobutaka Nakashima; Takashige Maeyama; Kazuyoshi Kuwano; Yoichi Nakanishi
[A case of rapidly deteriorated pulmonary aspergillosis with various clinical manifestations].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2004;42(6):491-5.
2004: Ichiro Inoshima; Kazuyoshi Kuwano; Naoki Hamada; Naoki Hagimoto; Michihiro Yoshimi; Takashige Maeyama; Akira Takeshita; Shiro Kitamoto; Kensuke Egashira; Nobuyuki Hara
Anti-monocyte chemoattractant protein-1 gene therapy attenuates pulmonary fibrosis in mice.
American journal of physiology. Lung cellular and molecular physiology 2004;286(5):L1038-44.
2004: Ichiro Inoshima; Kazuyoshi Kuwano; Naoki Hamada; Michihiro Yoshimi; Takashige Maeyama; Naoki Hagimoto; Yoichi Nakanishi; Nobuyuki Hara
Induction of CDK inhibitor p21 gene as a new therapeutic strategy against pulmonary fibrosis.
American journal of physiology. Lung cellular and molecular physiology 2004;286(4):L727-33.
2004: Masaki Fujita; Qing Ye; Hiroshi Ouchi; N Nakashima; N Hamada; Naoki Hagimoto; Kazuyoshi Kuwano; Robert J Mason; Yoichi Nakanishi
Retinoic acid fails to reverse emphysema in adult mouse models.
Thorax 2004;59(3):224-30.
2003: Naomi Yamasaki; Michihiro Yoshimi; Hiroyuki Inoue; Miiru Izumi; Naoki Hagimoto; Kazuyoshi Kuwano; Nobuyuki Hara
[Chronic hypersensitivity pneumonitis complicated by recurrent pneumothorax].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2003;92(2):310-2.
2003: Kazuyoshi Kuwano; Nobutaka Nakashima; Ichiro Inoshima; Naoki Hagimoto; Masaki Fujita; Michihiro Yoshimi; Takashige Maeyama; Naoki Hamada; Kentaro Watanabe; Nobuyuki Hara
Oxidative stress in lung epithelial cells from patients with idiopathic interstitial pneumonias.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2003;21(2):232-40.
2002: Takako Nakano; Satoru Fukuyama; Koji Inoue; Hiromasa Inoue; Naoki Hagimoto; Masaki Fujita; Kazuyoshi Kuwano; Nobuyuki Hara
[A case of sarcoidosis and idiopathic thrombocytopenic purpura accompanied with invasive pulmonary aspergillosis].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2002;40(12):945-9.
2002: Kazuyoshi Kuwano; Naoki Hagimoto; Takashige Maeyama; Masaki Fujita; Michihiro Yoshimi; Ichiro Inoshima; Nobutaka Nakashima; Naoki Hamada; Kentaro Watanabe; Nobuyuki Hara
Mitochondria-mediated apoptosis of lung epithelial cells in idiopathic interstitial pneumonias.
Laboratory investigation; a journal of technical methods and pathology 2002;82(12):1695-706.
2002: Koichiro Yoshida; Kazuyoshi Kuwano; Naoki Hagimoto; Kentaro Watanabe; Tokuji Matsuba; Masaki Fujita; Ichiro Inoshima; Nobuyuki Hara
MAP kinase activation and apoptosis in lung tissues from patients with idiopathic pulmonary fibrosis.
The Journal of pathology 2002;198(3):388-96.
2002: T Tanaka; Michihiro Yoshimi; Takashige Maeyama; Naoki Hagimoto; Kazuyoshi Kuwano; Nobuyuki Hara
Resistance to Fas-mediated apoptosis in human lung fibroblast.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2002;20(2):359-68.
2002: Naoki Hagimoto; Kazuyoshi Kuwano; Ichiro Inoshima; Michihiro Yoshimi; Norio Nakamura; Masaki Fujita; Takashige Maeyama; Nobuyuki Hara
TGF-beta 1 as an enhancer of Fas-mediated apoptosis of lung epithelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2002;168(12):6470-8.
2002: Naoki Hagimoto; Kazuyoshi Kuwano; Nobuyuki Hara
[The roles of apoptosis in lung injury].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2002;40(5):343-9.
2002: Kazuyoshi Kuwano; Takashige Maeyama; Ichiro Inoshima; Kiyoshi Ninomiya; Naoki Hagimoto; Michihiro Yoshimi; Masaki Fujita; Norio Nakamura; Kamon Shirakawa; Nobuyuki Hara
Increased circulating levels of soluble Fas ligand are correlated with disease activity in patients with fibrosing lung diseases.
Respirology (Carlton, Vic.) 2002;7(1):15-21.
2001: A Tanaka; Kazuyoshi Kuwano; Tokuji Matsuba; M Kawasaki; Koichiro Yoshida; Naoki Hagimoto; Nobuyuki Hara
[A case of sarcoidosis involving multiple organs that showed significant improvement as the serum KL-6 level fell after steroid therapy].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2001;39(12):915-9.
2001: K Kuwano; Naoki Hagimoto; N Hara
Molecular mechanisms of pulmonary fibrosis and current treatment.
Current molecular medicine 2001;1(5):551-73.
2001: Kazuyoshi Kuwano; Satoru Fukuyama; Tomomi Ikegami; Hiroshi Koto; Naoki Hagimoto; Tokuji Matsuba; N Fujita; Nobuyuki Hara
[An autopsy case of idiopathic interstitial pneumonia with diffuse alveolar hemorrhage due to acute exacerbation].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 2001;39(10):787-91.
2001: Takashige Maeyama; Kazuyoshi Kuwano; M Kawasaki; R Kunitake; Naoki Hagimoto; Nobuyuki Hara
Attenuation of bleomycin-induced pneumopathy in mice by monoclonal antibody to interleukin-12.
American journal of physiology. Lung cellular and molecular physiology 2001;280(6):L1128-37.
2001: Takashige Maeyama; Kazuyoshi Kuwano; M Kawasaki; R Kunitake; Naoki Hagimoto; Tokuji Matsuba; Michihiro Yoshimi; Ichiro Inoshima; Koichiro Yoshida; Nobuyuki Hara
Upregulation of Fas-signalling molecules in lung epithelial cells from patients with idiopathic pulmonary fibrosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;17(2):180-9.
2001: Kazuyoshi Kuwano; R Kunitake; Takashige Maeyama; Naoki Hagimoto; M Kawasaki; Tokuji Matsuba; Michihiro Yoshimi; Ichiro Inoshima; Koichiro Yoshida; Nobuyuki Hara
Attenuation of bleomycin-induced pneumopathy in mice by a caspase inhibitor.
American journal of physiology. Lung cellular and molecular physiology 2001;280(2):L316-25.
2001: R Kunitake; Kazuyoshi Kuwano; Koichiro Yoshida; Takashige Maeyama; M Kawasaki; Naoki Hagimoto; Nobuyuki Hara
KL-6, surfactant protein A and D in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis.
Respiration; international review of thoracic diseases 2001;68(5):488-95.
2000: Kazuyoshi Kuwano; M Kawasaki; Takashige Maeyama; Naoki Hagimoto; N Nakamura; K Shirakawa; Nobuyuki Hara
Soluble form of fas and fas ligand in BAL fluid from patients with pulmonary fibrosis and bronchiolitis obliterans organizing pneumonia.
Chest 2000;118(2):451-8.
2000: M Kawasaki; Kazuyoshi Kuwano; Naoki Hagimoto; Tokuji Matsuba; R Kunitake; T Tanaka; Takashige Maeyama; Nobuyuki Hara
Protection from lethal apoptosis in lipopolysaccharide-induced acute lung injury in mice by a caspase inhibitor.
The American journal of pathology 2000;157(2):597-603.
2000: Kazuyoshi Kuwano; Naoki Hagimoto; M Kawasaki; N Nakamura; K Shirakawa; Takashige Maeyama; Nobuyuki Hara
Expression of FasL and Fas protein and their soluble form in patients with hypersensitivity pneumonitis.
International archives of allergy and immunology 2000;122(3):209-15.
2000: M Kawasaki; Kazuyoshi Kuwano; Yoichi Nakanishi; Naoki Hagimoto; Koichi Takayama; Zhijun Li; Takashige Maeyama; Michihiro Yoshimi; Nobuyuki Hara
Analysis of Fas and Fas ligand expression and function in lung cancer cell lines.
European journal of cancer (Oxford, England : 1990) 2000;36(5):656-63.
2000: Kazuyoshi Kuwano; Naoki Hagimoto; T Tanaka; M Kawasaki; R Kunitake; H Miyazaki; Y Kaneko; Tokuji Matsuba; Takashige Maeyama; Nobuyuki Hara
Expression of apoptosis-regulatory genes in epithelial cells in pulmonary fibrosis in mice.
The Journal of pathology 2000;190(2):221-9.
2000: Y Kaneko; Kazuyoshi Kuwano; R Kunitake; M Kawasaki; Naoki Hagimoto; Nobuyuki Hara
B7-1, B7-2 and class II MHC molecules in idiopathic pulmonary fibrosis and bronchiolitis obliterans-organizing pneumonia.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;15(1):49-55.
1999: Naoki Hagimoto; Kazuyoshi Kuwano; M Kawasaki; Michihiro Yoshimi; Y Kaneko; R Kunitake; Takashige Maeyama; T Tanaka; Nobuyuki Hara
Induction of interleukin-8 secretion and apoptosis in bronchiolar epithelial cells by Fas ligation.
American journal of respiratory cell and molecular biology 1999;21(3):436-45.
1999: Kazuyoshi Kuwano; Naoki Hagimoto; M Kawasaki; T Yatomi; N Nakamura; S Nagata; T Suda; R Kunitake; Takashige Maeyama; H Miyazaki; Nobuyuki Hara
Essential roles of the Fas-Fas ligand pathway in the development of pulmonary fibrosis.
The Journal of clinical investigation 1999;104(1):13-9.
1999: R Kunitake; Kazuyoshi Kuwano; H Miyazaki; Naoki Hagimoto; Y Nomoto; Nobuyuki Hara
Apoptosis in the course of granulomatous inflammation in pulmonary sarcoidosis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1999;13(6):1329-37.
1999: Kazuyoshi Kuwano; Y Kaneko; Naoki Hagimoto; M Kawasaki; R Kunitake; T Tanaka; Takashige Maeyama; H Miyazaki; Tokuji Matsuba; Nobuyuki Hara
Expression of B7-1, B7-2, and interleukin-12 in anti-Fas antibody-induced pulmonary fibrosis in mice.
International archives of allergy and immunology 1999;119(2):112-9.
1999: Y Kaneko; Kazuyoshi Kuwano; R Kunitake; M Kawasaki; Naoki Hagimoto; H Miyazaki; Takashige Maeyama; T Tanaka; Tokuji Matsuba; Nobuyuki Hara
Immunohistochemical localization of B7 costimulating molecules and major histocompatibility complex class II antigen in pulmonary sarcoidosis.
Respiration; international review of thoracic diseases 1999;66(4):343-8.
1999: Kazuyoshi Kuwano; H Miyazaki; Naoki Hagimoto; M Kawasaki; Masaki Fujita; R Kunitake; Y Kaneko; Nobuyuki Hara
The involvement of Fas-Fas ligand pathway in fibrosing lung diseases.
American journal of respiratory cell and molecular biology 1999;20(1):53-60.
1998: Masaki Fujita; Kazuyoshi Kuwano; R Kunitake; Naoki Hagimoto; H Miyazaki; Y Kaneko; M Kawasaki; Takashige Maeyama; Nobuyuki Hara
Endothelial cell apoptosis in lipopolysaccharide-induced lung injury in mice.
International archives of allergy and immunology 1998;117(3):202-8.
1998: R Kunitake; Kazuyoshi Kuwano; H Miyazaki; M Kawasaki; Naoki Hagimoto; Masaki Fujita; Y Kaneko; Nobuyuki Hara
Expression of p53, p21 (Waf1/Cip1/Sdi1) and Fas antigen in collagen vascular and granulomatous lung diseases.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(4):920-5.
1998: Kazuyoshi Kuwano; Naoki Hagimoto; M Kawasaki; Nobuyuki Hara
[The roles of apoptosis in lung injury and fibrosis].
Nihon Kokyūki Gakkai zasshi = the journal of the Japanese Respiratory Society 1998;36(9):739-44.
1998: Y Kaneko; Kazuyoshi Kuwano; Naoki Hagimoto; H Miyazaki; M Kawasaki; Masaki Fujita; R Kunitake; Takashige Maeyama; Nobuyuki Hara
Expression of B7-1, B7-2, and interleukin 12 in bleomycin-induced pneumopathy in mice.
International archives of allergy and immunology 1998;116(4):306-12.
1997: Y Nomoto; Kazuyoshi Kuwano; Naoki Hagimoto; R Kunitake; M Kawasaki; Nobuyuki Hara
Apoptosis and Fas/Fas ligand mRNA expression in acute immune complex alveolitis in mice.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(10):2351-9.
1997: Naoki Hagimoto; Kazuyoshi Kuwano; H Miyazaki; R Kunitake; Masaki Fujita; M Kawasaki; Y Kaneko; Nobuyuki Hara
Induction of apoptosis and pulmonary fibrosis in mice in response to ligation of Fas antigen.
American journal of respiratory cell and molecular biology 1997;17(3):272-8.
1997: Kazuyoshi Kuwano; Y Nomoto; R Kunitake; Naoki Hagimoto; Tokuji Matsuba; Yoichi Nakanishi; Nobuyuki Hara
Detection of adenovirus E1A DNA in pulmonary fibrosis using nested polymerase chain reaction.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1997;10(7):1445-9.
1997: Kazuyoshi Kuwano; Naoki Hagimoto; Y Nomoto; M Kawasaki; R Kunitake; Masaki Fujita; H Miyazaki; Nobuyuki Hara
P53 and p21 (Waf1/Cip1) mRNA expression associated with DNA damage and repair in acute immune complex alveolitis in mice.
Laboratory investigation; a journal of technical methods and pathology 1997;76(2):161-9.
1997: Kazuyoshi Kuwano; M Kawasaki; R Kunitake; Naoki Hagimoto; Y Nomoto; Tokuji Matsuba; Yoichi Nakanishi; Nobuyuki Hara
Detection of group C adenovirus DNA in small-cell lung cancer with the nested polymerase chain reaction.
Journal of cancer research and clinical oncology 1997;123(7):377-82.
1997: Y Nomoto; Kazuyoshi Kuwano; Naoki Hagimoto; R Kunitake; Miyuki Tsuda; Nobuyuki Hara
Aspergillus fumigatus Asp fI DNA is prevalent in sputum from patients with coal workers' pneumoconiosis.
Respiration; international review of thoracic diseases 1997;64(4):291-5.
1997: H Matsuki; Kazuyoshi Kuwano; Michihiro Yoshimi; Y Nomoto; R Kunitake; Naoki Hagimoto; Nobuyuki Hara
[Spontaneous recovery from cytomegalovirus pneumonia].
Nihon Kyōbu Shikkan Gakkai zasshi 1997;35(1):67-71.
1997: Naoki Hagimoto; Kazuyoshi Kuwano; Y Nomoto; R Kunitake; Nobuyuki Hara
Apoptosis and expression of Fas/Fas ligand mRNA in bleomycin-induced pulmonary fibrosis in mice.
American journal of respiratory cell and molecular biology 1997;16(1):91-101.
1996: Kazuyoshi Kuwano; R Kunitake; M Kawasaki; Y Nomoto; Naoki Hagimoto; Y Nakanishi; Nobuyuki Hara
P21Waf1/Cip1/Sdi1 and p53 expression in association with DNA strand breaks in idiopathic pulmonary fibrosis.
American journal of respiratory and critical care medicine 1996;154(2 Pt 1):477-83.
1996: K Takano; Koichi Takayama; Hitoo Nakano; Naoki Hagimoto; Yoichi Nakanishi; Nobuyuki Hara
[Small cell lung cancer associated with ectopic ACTH syndrome].
Nihon Kyōbu Shikkan Gakkai zasshi 1996;34(2):220-5.
1996: Naoki Hagimoto; Kazuyoshi Kuwano; Y Nomoto; R Kunitake; S Hashimoto; Nobuyuki Hara
[DNA strand breaks in epithelial cells from mice with bleomycin induced pulmonary fibrosis].
Nihon Kyōbu Shikkan Gakkai zasshi 1996;34(1):3-8.
1994: T Furuno; Nobuyuki Hara; Naoki Hagimoto; N Mori; H Muranishi
Multiple pulmonary nodules manifested in a patient with NK cell granular lymphocyte proliferative disorder.
Chest 1994;105(6):1893-5.
1994: Y Nomoto; Y Miyagawa; T Shiraishi; H Hirano; M Kawasaki; H Ogino; T Furuno; Naoki Hagimoto; S Hayashi; K Yagawa
Tyrosine-specific protein kinase participates in the pathogenesis of acute immune complex alveolitis in rats.
Respiration; international review of thoracic diseases 1994;61(1):19-22.