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Harvey Hahn

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Stephen B Liggett; Sharon Cresci; Reagan J Kelly; Faisal M Syed; Scot J Matkovich; Harvey S Hahn; Abhinav Diwan; Jeffrey S Martini; Li Sparks; Rohan R Parekh; John A Spertus; Walter J Koch; Sharon L R Kardia; Gerald W Dorn
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure.
Stephen B Liggett; Reagan J Kelly; Rohan R Parekh; Scot J Matkovich; Bonnie J Benner; Harvey S Hahn; Faisal M Syed; Anita S Galvez; Karen L Case; Nancy McGuire; Amy Odley; Li Sparks; Sharon L R Kardia; Gerald W Dorn
A functional polymorphism of the Galphaq (GNAQ) gene is associated with accelerated mortality in African-American heart failure.
Abhinav Diwan; Maike Krenz; Faisal M Syed; Janaka Wansapura; Xiaoping Ren; Andrew G Koesters; Hairong Li; Lorrie A Kirshenbaum; Harvey S Hahn; Jeffrey Robbins; W Keith Jones; Gerald W Dorn
Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice.

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All Publications

2008: Stephen B Liggett; Sharon Cresci; Reagan J Kelly; Faisal M Syed; Scot J Matkovich; Harvey S Hahn; Abhinav Diwan; Jeffrey S Martini; Li Sparks; Rohan R Parekh; John A Spertus; Walter J Koch; Sharon L R Kardia; Gerald W Dorn
A GRK5 polymorphism that inhibits beta-adrenergic receptor signaling is protective in heart failure.
Nature medicine 2008;14(5):510-7.
2007: Stephen B Liggett; Reagan J Kelly; Rohan R Parekh; Scot J Matkovich; Bonnie J Benner; Harvey S Hahn; Faisal M Syed; Anita S Galvez; Karen L Case; Nancy McGuire; Amy Odley; Li Sparks; Sharon L R Kardia; Gerald W Dorn
A functional polymorphism of the Galphaq (GNAQ) gene is associated with accelerated mortality in African-American heart failure.
Human molecular genetics 2007;16(22):2740-50.
2007: Abhinav Diwan; Maike Krenz; Faisal M Syed; Janaka Wansapura; Xiaoping Ren; Andrew G Koesters; Hairong Li; Lorrie A Kirshenbaum; Harvey S Hahn; Jeffrey Robbins; W Keith Jones; Gerald W Dorn
Inhibition of ischemic cardiomyocyte apoptosis through targeted ablation of Bnip3 restrains postinfarction remodeling in mice.
The Journal of clinical investigation 2007;117(10):2825-33.
2007: Tomoki Nakamura; Melissa C Colbert; Maike Krenz; Jeffery D Molkentin; Harvey S Hahn; Gerald W Dorn; Jeffrey Robbins
Mediating ERK 1/2 signaling rescues congenital heart defects in a mouse model of Noonan syndrome.
The Journal of clinical investigation 2007;117(8):2123-32.
2007: Cristopher A Meyer; E William Schneeberger; Rhonda S Strunk; Achala S Vagal; Randall K Wolf; Joseph E Hall; John R Mehall; Harvey S Hahn
Impact of Preoperative 64-Slice CT Scanning on Mini-Maze Atrial Fibrillation Surgery.
Innovations (Philadelphia, Pa.) 2007;2(4):169-75.
2007: Anita S Galvez; Abhinav Diwan; Amy Odley; Harvey S Hahn; Hanna Osinska; Jaime G Melendez; Jeffrey Robbins; Roy A Lynch; Yehia Marreez; Gerald W Dorn
Cardiomyocyte degeneration with calpain deficiency reveals a critical role in protein homeostasis.
Circulation research 2007;100(7):1071-8.
2006: Karyn L Butler; Lynn C Huffman; Sheryl E Koch; Harvey S Hahn; Judith K Gwathmey
STAT-3 activation is necessary for ischemic preconditioning in hypertrophied myocardium.
American journal of physiology. Heart and circulatory physiology 2006;291(2):H797-803.
2006: Wen Zhao; Qunying Yuan; Jiang Qian; Jason R Waggoner; Anand Pathak; Guoxiang Chu; Bryan Mitton; Xiaoyin Sun; Jay Jin; Julian C Braz; Harvey S Hahn; Yehia Marreez; Faisal M Syed; Piero Pollesello; Arto Annila; Hong-Sheng Wang; Jo El J Schultz; Jeffery D Molkentin; Stephen B Liggett; Gerald W Dorn; Evangelia G Kranias
The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling.
Circulation 2006;113(7):995-1004.
2005: Marta Rubio; Ilona Bodi; Geraldine A Fuller-Bicer; Harvey S Hahn; Muthu Periasamy; Arnold Schwartz
Sarcoplasmic reticulum adenosine triphosphatase overexpression in the L-type Ca2+ channel mouse results in cardiomyopathy and Ca2+ -induced arrhythmogenesis.
Journal of cardiovascular pharmacology and therapeutics 2005;10(4):235-49.
2005: Sakthivel Sadayappan; James Gulick; Hanna Osinska; Lisa A Martin; Harvey S Hahn; Gerald W Dorn; Raisa Klevitsky; Christine E Seidman; Jonathan G Seidman; Jeffrey Robbins
Cardiac myosin-binding protein-C phosphorylation and cardiac function.
Circulation research 2005;97(11):1156-63.
2005: Faisal M Syed; Abhinav Diwan; Harvey S Hahn
Murine echocardiography: a practical approach for phenotyping genetically manipulated and surgically modeled mice.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2005;18(9):982-90.
2005: Faisal M Syed; Harvey S Hahn; Amy Odley; Yiru Guo; Jesus G Vallejo; Roy A Lynch; Douglas L Mann; Roberto Bolli; Gerald W Dorn
Proapoptotic effects of caspase-1/interleukin-converting enzyme dominate in myocardial ischemia.
Circulation research 2005;96(10):1103-9.
2004: Faisal M Syed; Amy Odley; Harvey S Hahn; Eric W Brunskill; Roy A Lynch; Yehia Marreez; Atsushi Sanbe; Jeffrey Robbins; Gerald W Dorn
Physiological growth synergizes with pathological genes in experimental cardiomyopathy.
Circulation research 2004;95(12):1200-6.
2004: John G Quinlan; Harvey S Hahn; Brenda L Wong; John N Lorenz; Alexandra Wenisch; Linda S Levin
Evolution of the mdx mouse cardiomyopathy: physiological and morphological findings.
Neuromuscular disorders : NMD 2004;14(8-9):491-6.
2004: Amy Odley; Harvey S Hahn; Roy A Lynch; Yehia Marreez; Hanna Osinska; Jeffrey Robbins; Gerald W Dorn
Regulation of cardiac contractility by Rab4-modulated beta2-adrenergic receptor recycling.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(18):7082-7.
2004: Gerald W Dorn; Harvey S Hahn
Genetic factors in cardiac hypertrophy.
Annals of the New York Academy of Sciences 2004;1015():225-37.
2003: Harvey S Hahn; Yehia Marreez; Amy Odley; Amber Sterbling; Martin G Yussman; K Chad Hilty; Ilona Bodi; Stephen B Liggett; Arnold Schwartz; Gerald W Dorn
Protein kinase Calpha negatively regulates systolic and diastolic function in pathological hypertrophy.
Circulation research 2003;93(11):1111-9.
2003: Jeanne Mialet Perez; Deborah A Rathz; Natalia N Petrashevskaya; Harvey S Hahn; Lynne E Wagoner; Arnold Schwartz; Gerald W Dorn; Stephen B Liggett
Beta 1-adrenergic receptor polymorphisms confer differential function and predisposition to heart failure.
Nature medicine 2003;9(10):1300-5.
2003: Koichi Inagaki; Harvey S Hahn; Gerald W Dorn; Daria Mochly-Rosen
Additive protection of the ischemic heart ex vivo by combined treatment with delta-protein kinase C inhibitor and epsilon-protein kinase C activator.
Circulation 2003;108(7):869-75.
2003: Ilona Bodi; James N Muth; Harvey S Hahn; Natalia N Petrashevskaya; Marta Rubio; Sheryl E Koch; Gyula Varadi; Arnold Schwartz
Electrical remodeling in hearts from a calcium-dependent mouse model of hypertrophy and failure: complex nature of K+ current changes and action potential duration.
Journal of the American College of Cardiology 2003;41(9):1611-22.
2003: Kobra Haghighi; Fotis Kolokathis; Luke Pater; Roy A Lynch; Michio Asahi; Anthony O Gramolini; Guo-Chang Fan; Dimitris Tsiapras; Harvey S Hahn; Stamatis Adamopoulos; Stephen B Liggett; Gerald W Dorn; David H MacLennan; Dimitrios Th Kremastinos; Evangelia G Kranias
Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human.
The Journal of clinical investigation 2003;111(6):869-76.
2003: Qiujing Song; Albrecht G Schmidt; Harvey S Hahn; Andrew N Carr; Beate Frank; Luke Pater; Michael J Gerst; Karen Young; Brian D Hoit; Bradley K McConnell; Kobra Haghighi; Christine E Seidman; Jonathan G Seidman; Gerald W Dorn; Evangelia G Kranias
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
The Journal of clinical investigation 2003;111(6):859-67.
2002: Harvey S Hahn; Martin G Yussman; Tsuyoshi Toyokawa; Yehia Marreez; Thomas J Barrett; K Chad Hilty; Hanna Osinska; Jeffrey Robbins; Gerald W Dorn
Ischemic protection and myofibrillar cardiomyopathy: dose-dependent effects of in vivo deltaPKC inhibition.
Circulation research 2002;91(8):741-8.
2001: Guangyu Wu; Martin G Yussman; T J Barrett; Harvey S Hahn; Hanna Osinska; George M Hilliard; Xinkang Wang; Tsuyoshi Toyokawa; Atsuko Yatani; Roy A Lynch; Jeffrey Robbins; Gerald W Dorn
Increased myocardial Rab GTPase expression: a consequence and cause of cardiomyopathy.
Circulation research 2001;89(12):1130-7.