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Sinuhe Hahn
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127
Holzgreve, Wolfgang
47
Zhong, Xiao Yan
19
Troeger, Carolyn
14
Zimmermann, Bernhard
13
Li, Ying
11
Rusterholz, Corinne
11
Gupta, Anurag Kumar
9
Surbek, Daniel
8
Lapaire, Olav
7
Di Naro, Edoardo
6
Hristoskova, Sashka
6
Huppertz, Berthold
6
Gebhardt, Stefan
6
Tercanli, Sevgi
5
Kang, Anjeung
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All Publications
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2010: Kolla Varaprasad; Jenö Paul; Moes Suzette; Tercanli Sevgi; Lapaire Olav; Choolani Mahesh; Hahn Sinuhe
Quantitative proteomics analysis of maternal plasma in down syndrome pregnancies using isobaric tagging reagent (iTRAQ).
Journal of biomedicine & biotechnology 2010;2010():952047.
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2009: Hahn Sinuhe; Jackson Laird G; Kolla Varaprasad; Mahyuddin Aniza P; Choolani Mahesh
Noninvasive prenatal diagnosis of fetal aneuploidies and Mendelian disorders: new innovative strategies.
Expert review of molecular diagnostics 2009;9(6):613-21.
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2009: Fan Alex Xiu-Cheng; Radpour Ramin; Haghighi Mahdi Montazer; Kohler Corina; Xia Peng; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
Mitochondrial DNA content in paired normal and cancerous breast tissue samples from patients with breast cancer.
Journal of cancer research and clinical oncology 2009;135(8):983-9.
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2009: Grill Simon; Banzola Irina; Li Ying; Rekhviashvili Tea; Legler Tobias J; Müller Sina P; Zhong Xiao Yan; Hahn Sinuhe; Holzgreve Wolfgang
High throughput non-invasive determination of foetal Rhesus D status using automated extraction of cell-free foetal DNA in maternal plasma and mass spectrometry.
Archives of gynecology and obstetrics 2009;279(4):533-7.
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2009: Zachariah Rebecca; Schmid Seraina; Radpour Ramin; Buerki Nicole; Fan Alex Xiu-Cheng; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
Circulating cell-free DNA as a potential biomarker for minimal and mild endometriosis.
Reproductive biomedicine online 2009;18(3):407-11.
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2009: Choolani Mahesh; Narasimhan Kothandaraman; Kolla Varaprasad; Hahn Sinuhe
Proteomic technologies for prenatal diagnostics: advances and challenges ahead.
Expert review of proteomics 2009;6(1):87-101.
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2009: Grill Simon; Rusterholz Corinne; Zanetti-Dällenbach Rosanna; Tercanli Sevgi; Holzgreve Wolfgang; Hahn Sinuhe; Lapaire Olav
Potential markers of preeclampsia--a review.
Reproductive biology and endocrinology : RB&E 2009;7():70.
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2009: Li Ying; Di Naro Edoardo; Vitucci Angeloantonio; Grill Simon; Zhong Xiao Yan; Holzgreve Wolfgang; Hahn Sinuhe
Size fractionation of cell-free DNA in maternal plasma improves the detection of a paternally inherited beta-thalassemia point mutation by MALDI-TOF mass spectrometry.
Fetal diagnosis and therapy 2009;25(2):246-9.
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2008: Zimmermann Bernhard G; Grill Simon; Holzgreve Wolfgang; Zhong Xiao Yan; Jackson Laird G; Hahn Sinuhe
Digital PCR: a powerful new tool for noninvasive prenatal diagnosis?
Prenatal diagnosis 2008;28(12):1087-93.
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2008: Radpour Ramin; Haghighi Mahdi Montazer; Fan Alex Xiu-Cheng; Torbati Peyman Mohammadi; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
High-throughput hacking of the methylation patterns in breast cancer by in vitro transcription and thymidine-specific cleavage mass array on MALDI-TOF silico-chip.
Molecular cancer research : MCR 2008;6(11):1702-9.
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2008: El Tarhouny Shereen; Seefeld Martin; Fan Alex Xiu-Cheng; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
Comparison of serum VEGF and its soluble receptor sVEGFR1 with serum cell-free DNA in patients with breast tumor.
Cytokine 2008;44(1):65-9.
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2008: Seefeld M; El Tarhouny S; Fan A X C; Hahn S; Holzgreve W; Zhong X Y
Parallel assessment of circulatory cell-free DNA by PCR and nucleosomes by ELISA in breast tumors.
The International journal of biological markers 2008;23(2):69-73.
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2008: Hahn Sinuhe; Chitty Lyn S
Noninvasive prenatal diagnosis: current practice and future perspectives.
Current opinion in obstetrics & gynecology 2008;20(2):146-51.
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2008: van der Schoot C Ellen; Hahn Sinuhe; Chitty Lyn S
Non-invasive prenatal diagnosis and determination of fetal Rh status.
Seminars in fetal & neonatal medicine 2008;13(2):63-8.
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2008: Hahn Sinuhe; Chitty Lyn S
Non-invasive prenatal diagnosis: implications for antenatal diagnosis and the management of high-risk pregnancies.
Seminars in fetal & neonatal medicine 2008;13(2):55-6.
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2008: Hahn Sinuhe; Zhong Xiao Yan; Holzgreve Wolfgang
Recent progress in non-invasive prenatal diagnosis.
Seminars in fetal & neonatal medicine 2008;13(2):57-62.
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2008: Zanetti-Dällenbach Rosanna; Wight Edward; Fan Alex Xiu-Cheng; Lapaire Olav; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
Positive correlation of cell-free DNA in plasma/serum in patients with malignant and benign breast disease.
Anticancer research 2008;28(2A):921-5.
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2008: Li Ying; Finning Kirstin; Daniels Geoff; Hahn Sinuhe; Zhong Xiaoyan; Holzgreve Wolfgang
Noninvasive genotyping fetal Kell blood group (KEL1) using cell-free fetal DNA in maternal plasma by MALDI-TOF mass spectrometry.
Prenatal diagnosis 2008;28(3):203-8.
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2008: Chitty Lyn S; van der Schoot C Ellen; Hahn Sinuhe; Avent Neil D
SAFE--the Special Non-invasive Advances in Fetal and Neonatal Evaluation Network: aims and achievements.
Prenatal diagnosis 2008;28(2):83-8.
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2008: Gupta Anurag Kumar; Holzgreve Wolfgang; Hahn Sinuhe
Decrease in lipid levels of syncytiotrophoblast micro-particles reduced their potential to inhibit endothelial cell proliferation.
Archives of gynecology and obstetrics 2008;277(2):115-9.
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2008: Reddy Chinnapapagari Satheesh Kumar; Holzgreve Wolfgang; Hahn Sinuhe
Detection of new screening markers for fetal aneuploidies in maternal plasma: a proteomic approach.
Methods in molecular biology (Clifton, N.J.) 2008;444():311-26.
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2008: Li Ying; Holzgreve Wolfgang; Hahn Sinuhe
Size fractionation of cell-free DNA in maternal plasma and its application in noninvasive detection of fetal single gene point mutations.
Methods in molecular biology (Clifton, N.J.) 2008;444():239-51.
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2008: Huang Dorothy J; Mergenthaler-Gatfield Susanne; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
Isolation of cell-free DNA from maternal plasma using manual and automated systems.
Methods in molecular biology (Clifton, N.J.) 2008;444():203-8.
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2008: Mergenthaler-Gatfield Susanne; Holzgreve Wolfgang; Hahn Sinuhe
Spectral karyotyping (SKY): applications in prenatal diagnostics.
Methods in molecular biology (Clifton, N.J.) 2008;444():3-26.
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2008: Xiu-Cheng Fan Alex; Garritsen Henk S P; Tarhouny Shereen E L; Morris Michael; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
A rapid and accurate approach to identify single nucleotide polymorphisms of mitochondrial DNA using MALDI-TOF mass spectrometry.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2008;46(3):299-305.
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2007: Lapaire Olav; Volgmann Thorsten; Huang Dorothy; Hahn Sinuhe; Holzgreve Wolfgang; Zhong Xiao Yan
Maternal smoking: effect on circulating cell-free fetal and total DNA levels in maternal plasma from the second trimester.
Obstetrics and gynecology 2007;110(6):1358-63.
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2007: Hristoskova Sashka; Holzgreve Wolfgang; Hahn Sinuhe; Rusterholz Corinne
The chromatin of differentiating erythroblasts is cleaved into large size fragments independent of caspase activated DNase and apoptosis inducing factor.
Journal of cellular physiology 2007;213(2):490-4.
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2007: Zhong Xiao Yan; Ladewig Ariane; Schmid Seraina; Wight Edward; Hahn Sinuhe; Holzgreve Wolfgang
Elevated level of cell-free plasma DNA is associated with breast cancer.
Archives of gynecology and obstetrics 2007;276(4):327-31.
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2007: Zhong Xiao-Yan; von Mühlenen Ines; Li Ying; Kang Anjeung; Gupta Anurag Kumar; Tyndall Alan; Holzgreve Wolfgang; Hahn Sinuhe; Hasler Paul
Increased concentrations of antibody-bound circulatory cell-free DNA in rheumatoid arthritis.
Clinical chemistry 2007;53(9):1609-14.
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2007: Zhong Xiao Yan; Hahn Sinuhe; Steinborn Andrea; Holzgreve Wolfgang
Quantitative analysis of intact fetal cells in maternal plasma by real-time PCR.
European journal of obstetrics, gynecology, and reproductive biology 2007;133(1):20-4.
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2007: Gupta Anurag Kumar; Hasler Paul; Holzgreve Wolfgang; Hahn Sinuhe
Neutrophil NETs: a novel contributor to preeclampsia-associated placental hypoxia?
Seminars in immunopathology 2007;29(2):163-7.
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2007: Rusterholz Corinne; Hahn Sinuhe; Holzgreve Wolfgang
Role of placentally produced inflammatory and regulatory cytokines in pregnancy and the etiology of preeclampsia.
Seminars in immunopathology 2007;29(2):151-62.
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2007: Hahn Sinuhe; Zhong XiaoYan; Holzgreve Wolfgang
Non-invasive prenatal diagnosis of Down's syndrome.
Lancet 2007;369(9578):1997-8; author reply 1998-9.
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2007: Zanetti-Dällenbach R A; Schmid S; Wight E; Holzgreve W; Ladewing A; Hahn S; Zhong X Y
Levels of circulating cell-free serum DNA in benign and malignant breast lesions.
The International journal of biological markers 2007;22(2):95-9.
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2007: Holzgreve Wolfgang; Hahn Sinuhe; Zhong Xiao Yan; Lapaire Olav; Hösli Irene; Tercanli Sevgi; Mindy Peter
Genetic communication between fetus and mother: short- and long-term consequences.
American journal of obstetrics and gynecology 2007;196(4):372-81.
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2007: Troeger Carolyn; Surbek Daniel; Schöberlein Andreina; Schatt Stephan; Dudler Lisbeth; Hahn Sinuhe; Holzgreve Wolfgang
In utero haematopoietic stem cell transplantation. Experiences in mice, sheep and humans.
Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2007;137 Suppl 155():14S-19S.
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2007: Hristoskova Sashka; Holzgreve Wolfgang; Hahn Sinuhe; Rusterholz Corinne
Human mature erythroblasts are resistant to apoptosis.
Experimental cell research 2007;313(5):1024-32.
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2007: Zhong Xiao Yan; Hahn Sinuhe; Kiefer Vivian; Holzgreve Wolfgang
Is the quantity of circulatory cell-free DNA in human plasma and serum samples associated with gender, age and frequency of blood donations?
Annals of hematology 2007;86(2):139-43.
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2007: Lapaire Olav; Hösli Irène; Zanetti-Daellenbach Rosanna; Huang Dorothy; Jaeggi Carmen; Gatfield-Mergenthaler Susanne; Hahn Sinuhe; Holzgreve Wolfgang
Impact of fetal-maternal microchimerism on women's health--a review.
The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians 2007;20(1):1-5.
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2007: Li Ying; Page-Christiaens Godelieve C M L; Gille Johan J P; Holzgreve Wolfgang; Hahn Sinuhe
Non-invasive prenatal detection of achondroplasia in size-fractionated cell-free DNA by MALDI-TOF MS assay.
Prenatal diagnosis 2007;27(1):11-7.
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2007: Zimmermann Bernhard; Zhong Xiao Yan; Holzgreve Wolfgang; Hahn Sinuhe
Real-time quantitative polymerase chain reaction measurement of male fetal DNA in maternal plasma.
Methods in molecular medicine 2007;132():43-9.
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2007: Rusterholz Corinne; Holzgreve Wolfgang; Hahn Sinuhe
Oxidative stress alters the integrity of cell-free mRNA fragments associated with placenta-derived syncytiotrophoblast microparticles.
Fetal diagnosis and therapy 2007;22(4):313-7.
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2006: Li Ying; Hahn Sinuhe; Holzgreve Wolfgang
Recent developments in the detection of fetal single gene differences in maternal plasma and the role of size fractionation.
Annals of the New York Academy of Sciences 2006;1092():285-92.
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2006: Zhong Xiao Yan; Steinborn Andrea; Sohn Christoph; Holzgreve Wolfgang; Hahn Sinuhe
High levels of circulatory erythroblasts and cell-free DNA prior to intrauterine fetal death.
Prenatal diagnosis 2006;26(13):1272-3.
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2006: Diesch Claude Henri; Holzgreve Wolfgang; Hahn Sinuhe; Zhong Xiao Yan
Comparison of activin A and cell-free fetal DNA levels in maternal plasma from patients at high risk for preeclampsia.
Prenatal diagnosis 2006;26(13):1267-70.
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2006: Li Ying; Holzgreve Wolfgang; Kiefer Vivian; Hahn Sinuhe
Maldi-tof mass spectrometry compared with real-time PCR for detection of fetal cell-free DNA in maternal plasma.
Clinical chemistry 2006;52(12):2311-2.
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2006: Huang Dorothy J; Nelson Matthew R; Zimmermann Bernhard; Dudarewicz Lech; Wenzel Friedel; Spiegel Roland; Nagy Balint; Holzgreve Wolfgang; Hahn Sinuhe
Reliable detection of trisomy 21 using MALDI-TOF mass spectrometry.
Genetics in medicine : official journal of the American College of Medical Genetics 2006;8(11):728-34.
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2006: Li Ying; Wenzel Friedel; Holzgreve Wolfgang; Hahn Sinuhe
Genotyping fetal paternally inherited SNPs by MALDI-TOF MS using cell-free fetal DNA in maternal plasma: influence of size fractionation.
Electrophoresis 2006;27(19):3889-96.
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2006: Zimmermann Bernhard G; Holzgreve Wolfgang; Avent Neil; Hahn Sinuhe
Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma.
Annals of the New York Academy of Sciences 2006;1075():347-9.
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2006: Huang Dorothy J; Zimmermann Bernhard G; Holzgreve Wolfgang; Hahn Sinuhe
Improvement of methods for the isolation of cell-free fetal DNA from maternal plasma: comparison of a manual and an automated method.
Annals of the New York Academy of Sciences 2006;1075():308-12.
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2006: Li Ying; Hahn Deirdré; Wenzel Friedel; Holzgreve Wolfgang; Hahn Sinuhe
Detection of SNPs in the plasma of pregnant women and in the urine of kidney transplant recipients by mass spectrometry.
Annals of the New York Academy of Sciences 2006;1075():144-7.
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2006: Gupta Anurag; Hasler Paul; Gebhardt Stephan; Holzgreve Wolfgang; Hahn Sinuhe
Occurrence of neutrophil extracellular DNA traps (NETs) in pre-eclampsia: a link with elevated levels of cell-free DNA?
Annals of the New York Academy of Sciences 2006;1075():118-22.
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2006: Li Ying; Holzgreve Wolfgang; DI Naro Edoardo; Vitucci Angeloantonio; Hahn Sinuhe
Cell-free DNA in maternal plasma: is it all a question of size?
Annals of the New York Academy of Sciences 2006;1075():81-7.
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2006: Zhong Xiao Yan; Holzgreve Wolfgang; Hahn Sinuhe
Direct quantification of fetal cells in maternal blood by real-time PCR.
Prenatal diagnosis 2006;26(9):850-4.
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2006: Troeger Carolyn; Surbek Daniel; Schöberlein Andreina; Schatt Stephan; Dudler Lisbeth; Hahn Sinuhe; Holzgreve Wolfgang
In utero haematopoietic stem cell transplantation. Experiences in mice, sheep and humans.
Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2006;136(31-32):498-503.
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2006: Hahn Sinuhe; Gupta Anurag Kumar; Troeger Carolyn; Rusterholz Corinne; Holzgreve Wolfgang
Disturbances in placental immunology: ready for therapeutic interventions?
Springer seminars in immunopathology 2006;27(4):477-93.
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2006: Hristoskova Sashka; Holzgreve Wolfgang; Zhong Xiao Yan; Hahn Sinuhe
Macrophage migration inhibition factor is elevated in pregnancy, but not to a greater extent in preeclampsia.
Archives of gynecology and obstetrics 2006;274(1):25-8.
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2006: Gupta Anurag Kumar; Gebhardt Stefan; Hillermann Renate; Holzgreve Wolfgang; Hahn Sinuhe
Analysis of plasma elastase levels in early and late onset preeclampsia.
Archives of gynecology and obstetrics 2006;273(4):239-42.
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2006: Zhong Xiao Yan; Holzgreve Wolfgang; Tercanli Sevgi; Wenzel Friedel; Hahn Sinuhe
Cell-free foetal DNA in maternal plasma does not appear to be derived from the rich pool of cell-free foetal DNA in amniotic fluid.
Archives of gynecology and obstetrics 2006;273(4):221-6.
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2006: Zimmermann Bernhard; Levett Lisa; Holzgreve Wolfgang; Hahn Sinuhe
Use of real-time polymerase chain reaction for the detection of fetal aneuploidies.
Methods in molecular biology (Clifton, N.J.) 2006;336():83-100.
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2006: Zhong Xiao Yan; Holzgreve Wolfgang; Gebhardt Stefan; Hillermann Renate; Tofa Kashefa Carelse; Gupta Anurag Kumar; Huppertz Berthold; Hahn Sinuhe
Minimal alteration in the ratio of circulatory fetal DNA to fetal corticotropin-releasing hormone mRNA level in preeclampsia.
Fetal diagnosis and therapy 2006;21(3):246-9.
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2006: Troeger Carolyn; Holzgreve Wolfgang; Ladewig Ariane; Zhong Xiao Yan; Hahn Sinuhe
Examination of maternal plasma erythropoietin and activin A concentrations with regard to circulatory erythroblast levels in normal and preeclamptic pregnancies.
Fetal diagnosis and therapy 2006;21(1):156-60.
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2005: Huang Dorothy J; Zimmermann Bernhard G; Holzgreve Wolfgang; Hahn Sinuhe
Use of an automated method improves the yield and quality of cell-free fetal DNA extracted from maternal plasma.
Clinical chemistry 2005;51(12):2419-20.
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2005: Gupta Anurag Kumar; Rusterholz Corinne; Holzgreve Wolfgang; Hahn Sinuhe
Syncytiotrophoblast micro-particles do not induce apoptosis in peripheral T lymphocytes, but differ in their activity depending on the mode of preparation.
Journal of reproductive immunology 2005;68(1-2):15-26.
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2005: Babochkina Tatiana; Mergenthaler Susanne; Dinges Tatyana Maier; Holzgreve Wolfgang; Hahn Sinuhe
Direct detection of fetal cells in maternal blood: a reappraisal using a combination of two different Y chromosome-specific FISH probes and a single X chromosome-specific probe.
Archives of gynecology and obstetrics 2005;273(3):166-9.
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2005: Gupta Anurag Kumar; Hasler Paul; Holzgreve Wolfgang; Gebhardt Stefan; Hahn Sinuhe
Induction of neutrophil extracellular DNA lattices by placental microparticles and IL-8 and their presence in preeclampsia.
Human immunology 2005;66(11):1146-54.
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2005: Chiu Rossa W K; Chan Carol W M; Zhong Xiao-yan; Lapaire Olav; Holzgreve Wolfgang; Hahn Sinuhe; Lo Y M Dennis
Fetal rhesus D mRNA is not detectable in maternal plasma.
Clinical chemistry 2005;51(11):2210-1.
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2005: Li Ying; Hahn Deirdré; Holzgreve Wolfgang; Hahn Sinuhe
Ready detection of donor-specific single-nucleotide polymorphisms in the urine of renal transplant recipients by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry.
Clinical chemistry 2005;51(10):1903-4.
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2005: Hahn Sinuhe; Mergenthaler Susanne; Zimmermann Bernhard; Holzgreve Wolfgang
Nucleic acid based biosensors: the desires of the user.
Bioelectrochemistry (Amsterdam, Netherlands) 2005;67(2):151-4.
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2005: Gupta Anurag Kumar; Holzgreve Wolfgang; Hahn Sinuhe
Microparticle-free placentally derived soluble factors downmodulate the response of activated T cells.
Human immunology 2005;66(9):977-84.
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2005: Zhong Xiao Yan; Gebhardt Stefan; Hillermann Renate; Tofa Kashefa Carelse; Holzgreve Wolfgang; Hahn Sinuhe
Parallel assessment of circulatory fetal DNA and corticotropin-releasing hormone mRNA in early- and late-onset preeclampsia.
Clinical chemistry 2005;51(9):1730-3.
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2005: Zimmermann Bernhard; El-Sheikhah Ahmad; Nicolaides Kypros; Holzgreve Wolfgang; Hahn Sinuhe
Optimized real-time quantitative PCR measurement of male fetal DNA in maternal plasma.
Clinical chemistry 2005;51(9):1598-604.
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2005: Zhong Xiao Yan; Gebhardt Stefan; Hillermann Renate; Tofa Kashefa Carelse; Holzgreve Wolfgang; Hahn Sinuhe
Circulatory nucleosome levels are significantly increased in early and late-onset preeclampsia.
Prenatal diagnosis 2005;25(8):700-3.
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2005: Hahn S; Huppertz B; Holzgreve W
Fetal cells and cell free fetal nucleic acids in maternal blood: new tools to study abnormal placentation?
Placenta 2005;26(7):515-26.
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2005: Babochkina Tatiana; Mergenthaler Susanne; De Napoli Giuseppina; Hristoskova Sashka; Tercanli Sevgi; Holzgreve Wolfgang; Hahn Sinuhe
Numerous erythroblasts in maternal blood are impervious to fluorescent in situ hybridization analysis, a feature related to a dense compact nucleus with apoptotic character.
Haematologica 2005;90(6):740-5.
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2005: Gupta A Kumar; Rusterholz C; Holzgreve W; Hahn S
Constant IFNgamma mRNA to protein ratios in cord and adult blood T cells suggests regulation of IFNgamma expression in cord blood T cells occurs at the transcriptional level.
Clinical and experimental immunology 2005;140(2):282-8.
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2005: Schoeberlein Andreina; Holzgreve Wolfgang; Dudler Lisbeth; Hahn Sinuhe; Surbek Daniel V
Tissue-specific engraftment after in utero transplantation of allogeneic mesenchymal stem cells into sheep fetuses.
American journal of obstetrics and gynecology 2005;192(4):1044-52.
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2005: Babochkina Tatiana; Mergenthaler Susanne; Lapaire Olaf; Kiefer Vivian; Yura Hirofumi; Koike Kimie; Holzgreve Wolfgang; Hahn Sinuhe
Evaluation of a soybean lectin-based method for the enrichment of erythroblasts.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(3):329-30.
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2005: Mergenthaler Susanne; Babochkina Tatiana; Kiefer Vivian; Lapaire Olaf; Holzgreve Wolfgang; Hahn Sinuhe
FISH analysis of all fetal nucleated cells in maternal whole blood: improved specificity by the use of two Y-chromosome probes.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2005;53(3):319-22.
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2005: Chinnapapagari Satheesh Kumar Reddy; Holzgreve Wolfgang; Lapaire Olav; Zimmermann Bernhard; Hahn Sinuhe
Treatment of maternal blood samples with formaldehyde does not alter the proportion of circulatory fetal nucleic acids (DNA and mRNA) in maternal plasma.
Clinical chemistry 2005;51(3):652-5.
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2005: Zhong Xiao Yan; Holzgreve Wolfgang; Hoesli Irene; Hahn Sinuhe
Circulatory corticotropin-releasing hormone mRNA concentrations are increased in women with preterm delivery but not in those who respond to tocolytic treatment.
Clinical chemistry 2005;51(3):635-6.
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2005: Li Ying; Di Naro Edoardo; Vitucci Angeloantonio; Zimmermann Bernhard; Holzgreve Wolfgang; Hahn Sinuhe
Detection of paternally inherited fetal point mutations for beta-thalassemia using size-fractionated cell-free DNA in maternal plasma.
JAMA : the journal of the American Medical Association 2005;293(7):843-9.
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2005: Rusterholz Corinne; Gupta Anurag K; Huppertz Berthold; Holzgreve Wolfgang; Hahn Sinuhe
Soluble factors released by placental villous tissue: Interleukin-1 is a potential mediator of endothelial dysfunction.
American journal of obstetrics and gynecology 2005;192(2):618-24.
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2005: Gupta A K; Rusterholz C; Huppertz B; Malek A; Schneider H; Holzgreve W; Hahn S
A comparative study of the effect of three different syncytiotrophoblast micro-particles preparations on endothelial cells.
Placenta 2005;26(1):59-66.
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2004: Schoeberlein Andreina; Schatt Stephan; Troeger Carolyn; Surbek Daniel; Holzgreve Wolfgang; Hahn Sinuhe
Engraftment kinetics of human cord blood and murine fetal liver stem cells following in utero transplantation into immunodeficient mice.
Stem cells and development 2004;13(6):677-84.
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2004: Zhong Xiao Yan; Wang Yiming; Chen Suqin; Pan Xiaoying; Zhu Ninghu; Hahn Cornelia; Huppertz Berthold; Holzgreve Wolfgang; Hahn Sinuhe;
Circulating fetal DNA in maternal plasma is increased in pregnancies at high altitude and is further enhanced by preeclampsia.
Clinical chemistry 2004;50(12):2403-5.
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2004: Li Y; Holzgreve W; Page-Christiaens G C M L; Gille J J P; Hahn S
Improved prenatal detection of a fetal point mutation for achondroplasia by the use of size-fractionated circulatory DNA in maternal plasma--case report.
Prenatal diagnosis 2004;24(11):896-8.
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2004: Gupta Anurag Kumar; Holzgreve Wolfgang; Huppertz Berthold; Malek Antoine; Schneider Henning; Hahn Sinuhe
Detection of fetal DNA and RNA in placenta-derived syncytiotrophoblast microparticles generated in vitro.
Clinical chemistry 2004;50(11):2187-90.
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2004: Schoeberlein Andreina; Holzgreve Wolfgang; Dudler Lisbeth; Hahn Sinuhe; Surbek Daniel V
In utero transplantation of autologous and allogeneic fetal liver stem cells in ovine fetuses.
American journal of obstetrics and gynecology 2004;191(3):1030-6.
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2004: Zhong Xiao Yan; Wang Yiming; Chen Suqin; Labu; Pubuzhuoma; Gesangzhuogab; Ouzhuwangmu; Hahn Cornelia; Holzgreve Wolfgang; Hahn Sinuhe
Can circulatory fetal DNA be used to study placentation at high altitude?
Annals of the New York Academy of Sciences 2004;1022():124-8.
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2004: Li Ying; Zimmermann Bernhard; Rusterholz Corinne; Kang Anjeung; Holzgreve Wolfgang; Hahn Sinuhe
Size separation of circulatory DNA in maternal plasma permits ready detection of fetal DNA polymorphisms.
Clinical chemistry 2004;50(6):1002-11.
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2004: Johnson Kirby L; Dukes Kimberly A; Vidaver John; LeShane Erik S; Ramirez Idania; Weber William D; Bischoff Farideh Z; Hahn Sinuhe; Sharma Arun; Dang Dianne X; Hire Lisa M; Bianchi Diana W; Simpson Joe Leigh; Holzgreve Wolfgang; Elias Sherman; Klinger Katherine W
Interlaboratory comparison of fetal male DNA detection from common maternal plasma samples by real-time PCR.
Clinical chemistry 2004;50(3):516-21.
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2004: Hristoskova Sashka; Holzgreve Wolfgang; Hahn Sinuhe
Anti-phospholipid and anti-DNA antibodies are not associated with the elevated release of circulatory fetal DNA in pregnancies affected by preeclampsia.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2004;23(3):257-68.
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2003: Li Ying; Zhong Xiao Yan; Kang Anjeung; Troeger Carolyn; Holzgreve Wolfgang; Hahn Sinuhe
Inability to detect cell free fetal DNA in the urine of normal pregnant women nor in those affected by preeclampsia associated HELLP syndrome.
Journal of the Society for Gynecologic Investigation 2003;10(8):503-8.
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2003: Hristoskova Sashka; Holzgreve Wolfgang; Hahn Sinuhe
Fetal nucleated erythrocytes in maternal circulation do not display a classic membrane-associated apoptotic characteristic (phosphatidylserine exposure) despite being positive by terminal dUTP nuclear end labeling.
Clinical chemistry 2003;49(11):1934-7.
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2003: Li Y; Zimmermann B; Zhong X Y; Gupta A K; Holzgreve W; Hahn S
Determination of RHD zygosity using real-time quantitative PCR.
Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2003;133(31-32):442-5.
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2003: Li Ying; Hahn Deirdré; Zhong Xiao Yan; Thomson Peter D; Holzgreve Wolfgang; Hahn Sinuhe
Detection of donor-specific DNA polymorphisms in the urine of renal transplant recipients.
Clinical chemistry 2003;49(4):655-8.
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2003: Bischoff Farideh Z; Hahn Sinuhe; Johnson Kirby L; Simpson Joe Leigh; Bianchi Diana W; Lewis Dorothy E; Weber William D; Klinger Katherine; Elias Sherman; Jackson Laird G; Evans Mark I; Holzgreve Wolfgang; de la Cruz Felix
Intact fetal cells in maternal plasma: are they really there?
Lancet 2003;361(9352):139-40.
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2002: Hahn Sinuhe; Holzgreve Wolfgang
Fetal cells and cell-free fetal DNA in maternal blood: new insights into pre-eclampsia.
Human reproduction update 2002;8(6):501-8.
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2002: Hoesli Irene; Danek Milan; Lin Dexin; Li Ying; Hahn Sinuhe; Holzgreve Wolfgang
Circulating erythroblasts in maternal blood are not elevated before onset of preterm labor.
Obstetrics and gynecology 2002;100(5 Pt 1):992-6.
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2002: Hahn Sinuhe; Holzgreve Wolfgang
Prenatal diagnosis using fetal cells and cell-free fetal DNA in maternal blood: what is currently feasible?
Clinical obstetrics and gynecology 2002;45(3):649-56; discussion 730-2.
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2002: Zhong Xiao Yan; Holzgreve Wolfgang; Hahn Sinuhe
Cell-free fetal DNA in the maternal circulation does not stem from the transplacental passage of fetal erythroblasts.
Molecular human reproduction 2002;8(9):864-70.
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2002: Zimmermann Bernhard; Holzgreve Wolfgang; Wenzel Friedel; Hahn Sinuhe
Novel real-time quantitative PCR test for trisomy 21.
Clinical chemistry 2002;48(2):362-3.
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2002: Hahn Sinuhe; Zhong Xiao Yan; Holzgreve Wolfgang
Single cell PCR in laser capture microscopy.
Methods in enzymology 2002;356():295-301.
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2002: Holzgreve Wolfang; Hahn Sinuhe
[Non-invasive prenatal diagnosis--already a reality?]
Gynäkologisch-geburtshilfliche Rundschau 2002;42(2):84-6.
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2002: Zhong Xiao Yan; Holzgreve Wolfgang; Hahn Sinuhe
The levels of circulatory cell free fetal DNA in maternal plasma are elevated prior to the onset of preeclampsia.
Hypertension in pregnancy : official journal of the International Society for the Study of Hypertension in Pregnancy 2002;21(1):77-83.
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2001: Zhong X Y; Hahn D; Troeger C; Klemm A; Stein G; Thomson P; Holzgreve W; Hahn S
Cell-free DNA in urine: a marker for kidney graft rejection, but not for prenatal diagnosis?
Annals of the New York Academy of Sciences 2001;945():250-7.
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2001: Hahn S; Zhong X Y; Bürk M R; Troeger C; Kang A; Holzgreve W
Both maternal and fetal cell-free DNA in plasma fluctuate.
Annals of the New York Academy of Sciences 2001;945():141-4.
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2001: Zhong X Y; Holzgreve W; Hahn S
Circulatory fetal and maternal DNA in pregnancies at risk and those affected by preeclampsia.
Annals of the New York Academy of Sciences 2001;945():138-40.
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2001: Surbek D V; Danzer E; Steinmann C; Tichelli A; Wodnar-Filipowicz A; Hahn S; Holzgreve W
Effect of preeclampsia on umbilical cord blood hematopoietic progenitor-stem cells.
American journal of obstetrics and gynecology 2001;185(3):725-9.
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2001: Bürk M R; Troeger C; Brinkhaus R; Holzgreve W; Hahn S
Severely reduced presence of tissue macrophages in the basal plate of pre-eclamptic placentae.
Placenta 2001;22(4):309-16.
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2001: Zhong X Y; Holzgreve W; Hahn S
Risk free simultaneous prenatal identification of fetal Rhesus D status and sex by multiplex real-time PCR using cell free fetal DNA in maternal plasma.
Swiss medical weekly : official journal of the Swiss Society of Infectious Diseases, the Swiss Society of Internal Medicine, the Swiss Society of Pneumology 2001;131(5-6):70-4.
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2001: Zhong X Y; Laivuori H; Livingston J C; Ylikorkala O; Sibai B M; Holzgreve W; Hahn S
Elevation of both maternal and fetal extracellular circulating deoxyribonucleic acid concentrations in the plasma of pregnant women with preeclampsia.
American journal of obstetrics and gynecology 2001;184(3):414-9.
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2001: Holzgreve W; Zhong X Y; Burk M R; Hahn S
Enrichment of fetal cells and free fetal DNA from maternal blood: An insight into the Basel experience.
Early pregnancy (Online) 2001;5(1):43-4.
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2001: Holzgreve W; Li J J; Steinborn A; Külz T; Sohn C; Hodel M; Hahn S
Elevation in erythroblast count in maternal blood before the onset of preeclampsia.
American journal of obstetrics and gynecology 2001;184(2):165-8.
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2000: Zhong X Y; Bürk M R; Troeger C; Kang A; Holzgreve W; Hahn S
Fluctuation of maternal and fetal free extracellular circulatory DNA in maternal plasma.
Obstetrics and gynecology 2000;96(6):991-6.
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2000: Surbek D V; Steinmann C; Bürk M; Hahn S; Tichelli A; Holzgreve W
Developmental changes in adhesion molecule expressions in umbilical cord blood CD34 hematopoietic progenitor and stem cells.
American journal of obstetrics and gynecology 2000;183(5):1152-7.
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2000: Zhong X Y; Holzgreve W; Li J C; Aydinli K; Hahn S
High levels of fetal erythroblasts and fetal extracellular DNA in the peripheral blood of a pregnant woman with idiopathic polyhydramnios: case report.
Prenatal diagnosis 2000;20(10):838-41.
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2000: Zhong X Y; Bürk M R; Troeger C; Jackson L R; Holzgreve W; Hahn S
Fetal DNA in maternal plasma is elevated in pregnancies with aneuploid fetuses.
Prenatal diagnosis 2000;20(10):795-8.
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2000: Holzgreve W; Hahn S
Fetal cells in cervical mucus and maternal blood.
Baillière's best practice & research. Clinical obstetrics & gynaecology 2000;14(4):709-22.
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2000: Surbek D V; Holzgreve W; Steinmann C; Hahn S; Gratwohl A; Wodnar-Filipowicz A; Tichelli A
Preterm birth and the availability of cord blood for HPC transplantation.
Transfusion 2000;40(7):817-20.
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2000: Surbek D V; Visca E; Steinmann C; Tichelli A; Schatt S; Hahn S; Gratwohl A; Holzgreve W
Umbilical cord blood collection before placental delivery during cesarean delivery increases cord blood volume and nucleated cell number available for transplantation.
American journal of obstetrics and gynecology 2000;183(1):218-21.
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2000: Zhong X Y; Holzgreve W; Hahn S
Detection of fetal Rhesus D and sex using fetal DNA from maternal plasma by multiplex polymerase chain reaction.
BJOG : an international journal of obstetrics and gynaecology 2000;107(6):766-9.
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2000: Di Naro E; Ghezzi F; Vitucci A; Tannoia N; Campanale D; D'Addario V; Holzgreve W; Hahn S
Prenatal diagnosis of beta-thalassaemia using fetal erythroblasts enriched from maternal blood by a novel gradient.
Molecular human reproduction 2000;6(6):571-4.
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2000: Smits G; Holzgreve W; Hahn S
An examination of different Percoll density gradients and magnetic activated cell sorting (MACS) for the enrichment of fetal erythroblasts from maternal blood.
Archives of gynecology and obstetrics 2000;263(4):160-3.
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2000: Hahn S; Zhong X Y; Bürk M R; Troeger C; Holzgreve W
Multiplex and real-time quantitative PCR on fetal DNA in maternal plasma. A comparison with fetal cells isolated from maternal blood.
Annals of the New York Academy of Sciences 2000;906():148-52.
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2000: Brombacher V; Kiefer V; Troeger C; Vial Y; Minderer S; Holzgreve W; Hahn S
Choice of anticoagulant can influence the analysis using fluorescence in situ hybridization of fetal cells enriched from maternal blood.
Prenatal diagnosis 2000;20(3):257-9.
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2000: Hahn S; Zhong X Y; Troeger C; Burgemeister R; Gloning K; Holzgreve W
Current applications of single-cell PCR.
Cellular and molecular life sciences : CMLS 2000;57(1):96-105.
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1999: Troeger C; Zhong X Y; Burgemeister R; Minderer S; Tercanli S; Holzgreve W; Hahn S
Approximately half of the erythroblasts in maternal blood are of fetal origin.
Molecular human reproduction 1999;5(12):1162-5.
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1999: Hahn S; Kiefer V; Brombacher V; Troeger C; Holzgreve W
Fetal cells in maternal blood. An update from Basel.
European journal of obstetrics, gynecology, and reproductive biology 1999;85(1):101-4.
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1999: Troeger C; Holzgreve W; Hahn S
A comparison of different density gradients and antibodies for enrichment of fetal erythroblasts by MACS.
Prenatal diagnosis 1999;19(6):521-6.
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1998: Holzgreve W; Troeger C; Schatt S; Vial Y; Louwen F; Gloning K; Hahn S
[Prenatal diagnosis with fetal cells in maternal blood: report of experiences in Basal]
Schweizerische medizinische Wochenschrift 1998;128(43):1641-5.
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1998: Garvin A M; Holzgreve W; Hahn S
Highly accurate analysis of heterozygous loci bysingle cell PCR.
Nucleic acids research 1998;26(15):3468-72.
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1998: Holzgreve W; Di Naro E; Garvin A M; Troeger C; Hahn S
Prenatal diagnosis using fetal cells enriched from maternal blood.
Croatian medical journal 1998;39(2):115-20.
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1998: Holzgreve W; Ghezzi F; Di Naro E; Gänshirt D; Maymon E; Hahn S
Disturbed feto-maternal cell traffic in preeclampsia.
Obstetrics and gynecology 1998;91(5 Pt 1):669-72.
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1998: Hahn S; Garvin A M; Di Naro E; Holzgreve W
Allele drop-out can occur in alleles differing by a single nucleotide and is not alleviated by preamplification or minor template increments.
Genetic testing 1998;2(4):351-5.
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