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Brian Haines

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Richard W Heidebrecht; Melissa Chenard; Joshua Close; William K Dahlberg; Judith Fleming; Jonathan B Grimm; Julie E Hamill; Andreas Harsch; Brian B Haines; Bethany Hughes; Astrid M Kral; Richard E Middleton; Chandrasekhar Mushti; Nicole Ozerova; Alexander A Szewczak; Hongmei Wang; Kevin Wilson; David J Witter; J Paul Secrist; Thomas A Miller
Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2).
Brian B Haines; Kimberly A Bettano; Melissa Chenard; Raquel S Sevilla; Christopher Ware; Minilik H Angagaw; Christopher T Winkelmann; Christopher Tong; John F Reilly; Cyrille Sur; Weisheng Zhang
A quantitative volumetric micro-computed tomography method to analyze lung tumors in genetically engineered mouse models.
Joey L Methot; Christopher L Hamblett; Dawn M Mampreian; Joon Jung; Andreas Harsch; Alexander A Szewczak; William K Dahlberg; Richard E Middleton; Bethany Hughes; Judith C Fleming; Hongmei Wang; Astrid M Kral; Nicole Ozerova; Cruz Jonathan; Brian B Haines; Melissa Chenard; Candia M Kenific; J Paul Secrist; Thomas A Miller
SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2).

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All Publications

2009: Richard W Heidebrecht; Melissa Chenard; Joshua Close; William K Dahlberg; Judith Fleming; Jonathan B Grimm; Julie E Hamill; Andreas Harsch; Brian B Haines; Bethany Hughes; Astrid M Kral; Richard E Middleton; Chandrasekhar Mushti; Nicole Ozerova; Alexander A Szewczak; Hongmei Wang; Kevin Wilson; David J Witter; J Paul Secrist; Thomas A Miller
Exploring the pharmacokinetic properties of phosphorus-containing selective HDAC 1 and 2 inhibitors (SHI-1:2).
Bioorganic & medicinal chemistry letters 2009;19(7):2053-8.
2009: Brian B Haines; Kimberly A Bettano; Melissa Chenard; Raquel S Sevilla; Christopher Ware; Minilik H Angagaw; Christopher T Winkelmann; Christopher Tong; John F Reilly; Cyrille Sur; Weisheng Zhang
A quantitative volumetric micro-computed tomography method to analyze lung tumors in genetically engineered mouse models.
Neoplasia (New York, N.Y.) 2009;11(1):39-47.
2008: Joey L Methot; Christopher L Hamblett; Dawn M Mampreian; Joon Jung; Andreas Harsch; Alexander A Szewczak; William K Dahlberg; Richard E Middleton; Bethany Hughes; Judith C Fleming; Hongmei Wang; Astrid M Kral; Nicole Ozerova; Cruz Jonathan; Brian B Haines; Melissa Chenard; Candia M Kenific; J Paul Secrist; Thomas A Miller
SAR profiles of spirocyclic nicotinamide derived selective HDAC1/HDAC2 inhibitors (SHI-1:2).
Bioorganic & medicinal chemistry letters 2008;18(23):6104-9.
2008: David J Witter; Paul Harrington; Kevin J Wilson; Melissa Chenard; Judith C Fleming; Brian B Haines; Astrid M Kral; J Paul Secrist; Thomas A Miller
Optimization of biaryl Selective HDAC1&2 Inhibitors (SHI-1:2).
Bioorganic & medicinal chemistry letters 2008;18(2):726-31.
2006: Brian B Haines; Chun Jeih Ryu; Jianzhu Chen
Recombination activating genes (RAG) in lymphoma development.
Cell cycle (Georgetown, Tex.) 2006;5(9):913-6.
2006: Brian B Haines; Chun Jeih Ryu; Sandy Chang; Alexei Protopopov; Andreas Luch; Yun Hee Kang; Dobrin D Draganov; Maria F Fragoso; Sang Gi Paik; Hyo Jeong Hong; Ronald A DePinho; Jianzhu Chen
Block of T cell development in P53-deficient mice accelerates development of lymphomas with characteristic RAG-dependent cytogenetic alterations.
Cancer cell 2006;9(2):109-20.
2004: Chun Jeih Ryu; Brian B Haines; Hye Ran Lee; Yun Hee Kang; Dobrin D Draganov; Minhui Lee; Charles E Whitehurst; Hyo Jeong Hong; Jianzhu Chen
The T-cell receptor beta variable gene promoter is required for efficient V beta rearrangement but not allelic exclusion.
Molecular and cellular biology 2004;24(16):7015-23.
2003: Chun Jeih Ryu; Brian B Haines; Dobrin D Draganov; Yun Hee Kang; Charles E Whitehurst; Tara Schmidt; Hyo Jeong Hong; Jianzhu Chen
The T cell receptor beta enhancer promotes access and pairing of Dbeta and Jbeta gene segments during V(D)J recombination.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13465-70.
2002: Michael McManus; Brian B Haines; Christopher P Dillon; Charles E Whitehurst; Luk Van Parijs; Jianzhu Chen; Phillip A Sharp
Small interfering RNA-mediated gene silencing in T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(10):5754-60.
2002: Michael McManus; Christian P. Petersen; Brian B Haines; Jianzhu Chen; Phillip A Sharp
Gene silencing using micro-RNA designed hairpins.
RNA (New York, N.Y.) 2002;8(6):842-50.
2001: Brian B Haines; C V Angeles; A P Parmelee; P A McLean; Peter H Brodeur
Germline diversity of the expressed BALB/c VhJ558 gene family.
Molecular immunology 2001;38(1):9-18.
1999: E A Whitcomb; Brian B Haines; A P Parmelee; A M Pearlman; Peter H Brodeur
Germline structure and differential utilization of Igha and Ighb VH10 genes.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(3):1541-50.
1998: Brian B Haines; Peter H Brodeur
Accessibility changes across the mouse Igh-V locus during B cell development.
European journal of immunology 1998;28(12):4228-35.