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Janos Hajdu

Research Profile

Procedures

X Ray Crystallography

Concepts & Ideas

Chemicals & Drugs

Phenomena

Living Beings

Paracoccus

Co-author Network

Publications

TOP 3
H Thomas; N Timneanu; M Adolph; J Andreasson; Nora Berrah; Christoph Bostedt; John Bozek; LF DiMauro; Gilles Doumy; T Gorkhover; Janos Hajdu; A Helal; M Hoener; K Hoffmann; B Iwan; N Kandadai; J Keto; M Messerschmidt; Thomas Möller; B Murphy; D Rupp; S Schorb; M Marvin Seibert; Todd Ditmire
Explosions of xenon clusters in ultraintense femtosecond x-ray pulses from the LCLS free electron laser.
Emanuele Pedersoli; Michael J Pivovaroff; Gilio Sandrin; Joachim Schulz; Carlo Spezzani; Bruce W Woods; Marco Zangrando; Burkhard Kaulich; Maya Kiskinova; Andrea Locatelli; Ralf Hendrik Menk; Tevfik O Mentes; A J Nelson; Daniel M Bacescu; Saša Bajt; Miriam Barthelmess; Anton Barty; Michael J Bogan; Flavio Capotondi; Henry N Chapman; Daniele Cocco; Matthias Frank; Lars Gumprecht; Janos Hajdu
Multipurpose modular experimental station for the DiProI beamline of Fermi@Elettra free electron laser.
Carl Caleman; Gösta Huldt; Filipe R N C Maia; Carlos Ortiz; Fritz G Parak; Janos Hajdu; David van der Spoel; Henry N Chapman; Nicuşor Timneanu
On the feasibility of nanocrystal imaging using intense and ultrashort X-ray pulses.

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All Publications

2012: H Thomas; N Timneanu; M Adolph; J Andreasson; Nora Berrah; Christoph Bostedt; John Bozek; LF DiMauro; Gilles Doumy; T Gorkhover; Janos Hajdu; A Helal; M Hoener; K Hoffmann; B Iwan; N Kandadai; J Keto; M Messerschmidt; Thomas Möller; B Murphy; D Rupp; S Schorb; M Marvin Seibert; Todd Ditmire
Explosions of xenon clusters in ultraintense femtosecond x-ray pulses from the LCLS free electron laser.
Physical review letters 2012;108(13):133401.
2011: Emanuele Pedersoli; Michael J Pivovaroff; Gilio Sandrin; Joachim Schulz; Carlo Spezzani; Bruce W Woods; Marco Zangrando; Burkhard Kaulich; Maya Kiskinova; Andrea Locatelli; Ralf Hendrik Menk; Tevfik O Mentes; A J Nelson; Daniel M Bacescu; Saša Bajt; Miriam Barthelmess; Anton Barty; Michael J Bogan; Flavio Capotondi; Henry N Chapman; Daniele Cocco; Matthias Frank; Lars Gumprecht; Janos Hajdu
Multipurpose modular experimental station for the DiProI beamline of Fermi@Elettra free electron laser.
The Review of scientific instruments 2011;82(4):043711.
2011: Carl Caleman; Gösta Huldt; Filipe R N C Maia; Carlos Ortiz; Fritz G Parak; Janos Hajdu; David van der Spoel; Henry N Chapman; Nicuşor Timneanu
On the feasibility of nanocrystal imaging using intense and ultrashort X-ray pulses.
ACS nano 2011;5(1):139-46.
2011: J Andreasson; B Iwan; A Andrejczuk; E Abreu; M Bergh; Carl Caleman; A J Nelson; Sasa Bajt; J Chalupsky; Henry N Chapman; R R Fäustlin; V Hajkova; P A Heimann; B Hjörvarsson; Libor Juha; D Klinger; J Krzywinski; B Nagler; G K Pálsson; W Singer; M Marvin Seibert; R Sobierajski; S Toleikis; T Tschentscher; S M Vinko; R W Lee; Janos Hajdu; Nicusor Tîmneanu
Saturated ablation in metal hydrides and acceleration of protons and deuterons to keV energies with a soft-x-ray laser.
Physical review. E, Statistical, nonlinear, and soft matter physics 2011;83(1 Pt 2):016403.
2010: N D Loh; M J Bogan; V Elser; Anton Barty; S Boutet; Sasa Bajt; Janos Hajdu; T Ekeberg; F R N C Maia; J Schulz; M Marvin Seibert; B Iwan; N Timneanu; S Marchesini; I Schlichting; R L Shoeman; L Lomb; Matthias Frank; M Liang; Henry N Chapman
Cryptotomography: reconstructing 3D Fourier intensities from randomly oriented single-shot diffraction patterns.
Physical review letters 2010;104(22):225501.
2010: Stefan P Hau-Riege; Sébastien Boutet; Anton Barty; Sasa Bajt; Michael J Bogan; Matthias Frank; Jakob Andreasson; Bianca Iwan; M Marvin Seibert; Janos Hajdu; Anne Sakdinawat; J Schulz; Rolf Treusch; Henry N Chapman
Sacrificial tamper slows down sample explosion in FLASH diffraction experiments.
Physical review letters 2010;104(6):064801.
2009: Filipe R N C Maia; Tomas Ekeberg; Nicusor Tîmneanu; David van der Spoel; Janos Hajdu
Structural variability and the incoherent addition of scattered intensities in single-particle diffraction.
Physical review. E, Statistical, nonlinear, and soft matter physics 2009;80(3 Pt 1):031905.
2009: Conan K Wang; Shu-Hong Hu; Jennifer L Martin; Tove Sjögren; Janos Hajdu; Lars Bohlin; Per Claeson; Ulf Göransson; Johan Rosengren; Jun Tang; Ning-Hua Tan; David J Craik
Combined X-ray and NMR analysis of the stability of the cyclotide cystine knot fold that underpins its insecticidal activity and potential use as a drug scaffold.
The Journal of biological chemistry 2009;284(16):10672-83.
2008: Michael Bogan; W Henry Benner; Sébastien Boutet; Urs Rohner; Matthias Frank; Anton Barty; M Marvin Seibert; Filipe Maia; Stefano Marchesini; Sasa Bajt; Bruce Woods; Vincent Riot; Stefan P Hau-Riege; Martin Svenda; Erik Marklund; Eberhard Spiller; Janos Hajdu; Henry N Chapman
Single particle X-ray diffractive imaging.
Nano letters 2008;8(1):310-6.
2007: Henry N Chapman; Stefan P Hau-Riege; Michael Bogan; Sasa Bajt; Anton Barty; Sébastien Boutet; Stefano Marchesini; Matthias Frank; Bruce W Woods; W Henry Benner; Richard A London; Urs Rohner; Abraham Szöke; Eberhard Spiller; Thomas Möller; Christoph Bostedt; David A Shapiro; Marion Kuhlmann; Rolf Treusch; Elke Plönjes; Florian Burmeister; Magnus Bergh; Carl Caleman; Gösta Huldt; M Marvin Seibert; Janos Hajdu
Femtosecond time-delay X-ray holography.
Nature 2007;448(7154):676-9.
2007: Jacob Flyvholm Cramer; Peter A Nordberg; Janos Hajdu; Sara Lejon
Crystal structure of a bacterial albumin-binding domain at 1.4 A resolution.
FEBS letters 2007;581(17):3178-82.
2005: Gunilla H Carlsson; Peter Nicholls; Dimitri A Svistunenko; Gunnar I Berglund; Janos Hajdu
Complexes of horseradish peroxidase with formate, acetate, and carbon monoxide.
Biochemistry 2005;44(2):635-42.
2004: Linda M Oster; Anke C Terwisscha van Scheltinga; Karin Valegård; Alasdair MacKenzie Hose; Alain Dubus; Janos Hajdu; Inger Andersson
Conformational flexibility of the C terminus with implications for substrate binding and catalysis revealed in a new crystal form of deacetoxycephalosporin C synthase.
Journal of molecular biology 2004;343(1):157-71.
2004: Karin Valegård; Anke C Terwisscha van Scheltinga; Alain Dubus; Graziella Ranghino; Linda M Oster; Janos Hajdu; Inger Andersson
The structural basis of cephalosporin formation in a mononuclear ferrous enzyme.
Nature structural & molecular biology 2004;11(1):95-101.
2003: Anke C Terwisscha van Scheltinga; Karin Valegård; Janos Hajdu; Inger Andersson
MIR phasing using merohedrally twinned crystals.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 11):2017-22.
2003: Abraham Szöke; William G Scott; Janos Hajdu
Catalysis, evolution and life.
FEBS letters 2003;553(1-2):18-20.
2003: Gösta Huldt; A Szoke; Janos Hajdu
Diffraction imaging of single particles and biomolecules.
Journal of structural biology 2003;144(1-2):219-27.
2003: Euan H J Gordon; Tove Sjögren; Malin Löfqvist; Carsten D Richter; James W A Allen; Christopher W Higham; Janos Hajdu; Vilmos Fülöp; Stuart J Ferguson
Structure and kinetic properties of Paracoccus pantotrophus cytochrome cd1 nitrite reductase with the d1 heme active site ligand tyrosine 25 replaced by serine.
The Journal of biological chemistry 2003;278(14):11773-81.
2002: Gergely Katona; Rupert C Wilmouth; Penny A Wright; Gunnar I Berglund; Janos Hajdu; Richard Neutze; Christopher J Schofield
X-ray structure of a serine protease acyl-enzyme complex at 0.95-A resolution.
The Journal of biological chemistry 2002;277(24):21962-70.
2002: Gunnar I Berglund; Gunilla H Carlsson; Andrew T Smith; Hanna Szöke; Anette Henriksen; Janos Hajdu
The catalytic pathway of horseradish peroxidase at high resolution.
Nature 2002;417(6887):463-8.
2002: Gergely Katona; Gunnar I Berglund; Janos Hajdu; László Gráf; László Szilágyi
Crystal structure reveals basis for the inhibitor resistance of human brain trypsin.
Journal of molecular biology 2002;315(5):1209-18.
2002: Carrie M Wilmot; Tove Sjögren; Gunilla H Carlsson; Gunnar I Berglund; Janos Hajdu
Defining redox state of X-ray crystal structures by single-crystal ultraviolet-visible microspectrophotometry.
Methods in enzymology 2002;353():301-18.
2001: Anke C Terwisscha van Scheltinga; Karin Valegård; S Ramaswamy; Janos Hajdu; Inger Andersson
Multiple isomorphous replacement on merohedral twins: structure determination of deacetoxycephalosporin C synthase.
Acta crystallographica. Section D, Biological crystallography 2001;57(Pt 12):1776-85.
2001: Petter Persson; Sten Lunell; Abraham Szöke; B Ziaja; Janos Hajdu
Shake-up and shake-off excitations with associated electron losses in X-ray studies of proteins.
Protein science : a publication of the Protein Society 2001;10(12):2480-4.
2001: Tove Sjögren; Janos Hajdu
The Structure of an alternative form of Paracoccus pantotrophus cytochrome cd(1) nitrite reductase.
The Journal of biological chemistry 2001;276(31):29450-5.
2001: Rupert C Wilmouth; Karl Edman; Richard Neutze; Penny A Wright; Ian J Clifton; T R Schneider; Christopher J Schofield; Janos Hajdu
X-ray snapshots of serine protease catalysis reveal a tetrahedral intermediate.
Nature structural biology 2001;8(8):689-94.
2001: Tove Sjögren; Janos Hajdu
Structure of the bound dioxygen species in the cytochrome oxidase reaction of cytochrome cd1 nitrite reductase.
The Journal of biological chemistry 2001;276(16):13072-6.
2001: E Steensma; E Gordon; Linda M Oster; S J Ferguson; Janos Hajdu
Heme ligation and conformational plasticity in the isolated c domain of cytochrome cd1 nitrite reductase.
The Journal of biological chemistry 2001;276(8):5846-55.
2000: Janos Hajdu; Richard Neutze; Tove Sjögren; Karl Edman; Abraham Szöke; Rupert C Wilmouth; Carrie M Wilmot
Analyzing protein functions in four dimensions.
Nature structural biology 2000;7(11):1006-12.
2000: Tove Sjögren; Margareta Svensson-Ek; Janos Hajdu; Peter Brzezinski
Proton-coupled structural changes upon binding of carbon monoxide to cytochrome cd1: a combined flash photolysis and X-ray crystallography study.
Biochemistry 2000;39(36):10967-74.
2000: G Ranghino; E Scorza; Tove Sjögren; P A Williams; M Ricci; Janos Hajdu
Quantum mechanical interpretation of nitrite reduction by cytochrome cd1 nitrite reductase from Paracoccus pantotrophus.
Biochemistry 2000;39(36):10958-66.
2000: Richard Neutze; R Wouts; David van der Spoel; E Weckert; Janos Hajdu
Potential for biomolecular imaging with femtosecond X-ray pulses.
Nature 2000;406(6797):752-7.
1999: Carrie M Wilmot; Janos Hajdu; Michael J McPherson; Peter F Knowles; Simon E V Phillips
Visualization of dioxygen bound to copper during enzyme catalysis.
Science (New York, N.Y.) 1999;286(5445):1724-8.
1999: Karl Edman; peter nollert; Antoine Royant; Hassan Belrhali; Eva Pebay-Peyroula; Janos Hajdu; Richard Neutze; Ehud M Landau
High-resolution X-ray structure of an early intermediate in the bacteriorhodopsin photocycle.
Nature 1999;401(6755):822-6.
1999: Matthew D Lloyd; H J Lee; Karl Harlos; Z H Zhang; Jack E Baldwin; Christopher J Schofield; JM Charnock; C David Garner; T Hara; Anke C Terwisscha van Scheltinga; Karin Valegård; J A Viklund; Janos Hajdu; Inger Andersson; A Danielsson; Rama Bhikhabhai
Studies on the active site of deacetoxycephalosporin C synthase.
Journal of molecular biology 1999;287(5):943-60.
1998: Karin Valegård; Anke C Terwisscha van Scheltinga; Matthew D Lloyd; T Hara; S Ramaswamy; Anastassis Perraks; A Thompson; H J Lee; Jack E Baldwin; Christopher J Schofield; Janos Hajdu; Inger Andersson
Structure of a cephalosporin synthase.
Nature 1998;394(6695):805-9.
1997: P A Williams; Vilmos Fülöp; Elspeth F Garman; Neil Saunders; Stuart J Ferguson; Janos Hajdu
Haem-ligand switching during catalysis in crystals of a nitrogen-cycle enzyme.
Nature 1997;389(6649):406-12.
1997: Didier Nurizzo; M C Silvestrini; M Mathieu; Francesca Cutruzzolà; Dominique Bourgeois; Vilmos Fülöp; Janos Hajdu; Maurizio Brunori; Mariella Tegoni; Christian Cambillau
N-terminal arm exchange is observed in the 2.15 A crystal structure of oxidized nitrite reductase from Pseudomonas aeruginosa.
Structure (London, England : 1993) 1997;5(9):1157-71.
1997: Peter L Roach; Ian J Clifton; Charles Hensgens; N Shibata; Christopher J Schofield; Janos Hajdu; Jack E Baldwin
Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.
Nature 1997;387(6635):827-30.
1997: SC Baker; Neil Saunders; A C Willis; Stuart J Ferguson; Janos Hajdu; Vilmos Fülöp
Cytochrome cd1 structure: unusual haem environments in a nitrite reductase and analysis of factors contributing to beta-propeller folds.
Journal of molecular biology 1997;269(3):440-55.
1997: Rupert C Wilmouth; Ian J Clifton; C V Robinson; Peter L Roach; RT Aplin; NJ Westwood; Janos Hajdu; Christopher J Schofield
Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase.
Nature structural biology 1997;4(6):456-62.
1997: Richard Neutze; Janos Hajdu
Femtosecond time resolution in x-ray diffraction experiments.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(11):5651-5.
1997: JN Barlow; Jack E Baldwin; Ian J Clifton; E Gibson; Charles Hensgens; Janos Hajdu; T Hara; A Hassan; P John; Matthew D Lloyd; Peter L Roach; A Prescott; J K Robinson; Z H Zhang; Christopher J Schofield
Studies on non-haem ferrous-dependent oxygenases and oxidases.
Biochemical Society transactions 1997;25(1):86-90.
1996: Peter L Roach; Ian J Clifton; Charles Hensgens; N Shibata; A J Long; Richard W Strange; S Samar Hasnain; Christopher J Schofield; Jack E Baldwin; Janos Hajdu
Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies.
European journal of biochemistry / FEBS 1996;242(3):736-40.
1996: Patrice Gouet; H M Jouve; P A Williams; I Andersson; P Andreoletti; Laurent Nussaume; Janos Hajdu
Ferryl intermediates of catalase captured by time-resolved Weissenberg crystallography and UV-VIS spectroscopy.
Nature structural biology 1996;3(11):951-6.
1996: Derek Logan; X D Su; A Aberg; K Regnström; Janos Hajdu; Hans Eklund; Pär Nordlund
Crystal structure of reduced protein R2 of ribonucleotide reductase: the structural basis for oxygen activation at a dinuclear iron site.
Structure (London, England : 1993) 1996;4(9):1053-64.
1995: Vilmos Fülöp; C J Ridout; C Greenwood; Janos Hajdu
Crystal structure of the di-haem cytochrome c peroxidase from Pseudomonas aeruginosa.
Structure (London, England : 1993) 1995;3(11):1225-33.
1995: A Hadfield; Janos Hajdu; M S Chapman; M G Rossmann
Laue diffraction studies of human rhinovirus 14 and canine parvovirus.
Acta crystallographica. Section D, Biological crystallography 1995;51(Pt 6):859-70.
1995: P A Williams; Vilmos Fülöp; Y C Leung; C Chan; James W B Moir; G Howlett; Stuart J Ferguson; S E Radford; Janos Hajdu
Pseudospecific docking surfaces on electron transfer proteins as illustrated by pseudoazurin, cytochrome c550 and cytochrome cd1 nitrite reductase.
Nature structural biology 1995;2(11):975-82.
1995: Frédéric Vellieux; Janos Hajdu; Wim G J Hol
Refined 3.2 A structure of glycosomal holo glyceraldehyde phosphate dehydrogenase from Trypanosoma brucei brucei.
Acta crystallographica. Section D, Biological crystallography 1995;51(Pt 4):575-89.
1995: Peter L Roach; Ian J Clifton; Vilmos Fülöp; Karl Harlos; Geoffrey J Barton; Janos Hajdu; I Andersson; Christopher J Schofield; Jack E Baldwin
Crystal structure of isopenicillin N synthase is the first from a new structural family of enzymes.
Nature 1995;375(6533):700-4.
1995: Vilmos Fülöp; James W B Moir; Stuart J Ferguson; Janos Hajdu
The anatomy of a bifunctional enzyme: structural basis for reduction of oxygen to water and synthesis of nitric oxide by cytochrome cd1.
Cell 1995;81(3):369-77.
1995: Peter L Roach; Christopher J Schofield; Jack E Baldwin; Ian J Clifton; Janos Hajdu
Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans.
Protein science : a publication of the Protein Society 1995;4(5):1007-9.
1994: Y Fujishima; Pär Nordlund; G Pelosi; Christopher J Schofield; S J Cole; Jack E Baldwin; Janos Hajdu
Crystallization and preliminary X-ray diffraction studies on a recombinant isopenicillin N synthase from Cephalosporium acremonium.
Journal of molecular biology 1994;242(5):712-4.
1994: Vilmos Fülöp; R P Phizackerley; S M Soltis; Ian J Clifton; S Wakatsuki; J Erman; Janos Hajdu; S L Edwards
Laue diffraction study on the structure of cytochrome c peroxidase compound I.
Structure (London, England : 1993) 1994;2(3):201-8.
1994: A Hadfield; Janos Hajdu
On the photochemical release of phosphate from 3,5-dinitrophenyl phosphate in a protein crystal.
Journal of molecular biology 1994;236(4):995-1000.
1993: Vilmos Fülöp; James W B Moir; Stuart J Ferguson; Janos Hajdu
Crystallization and preliminary crystallographic study of cytochrome cd1 nitrite reductase from Thiosphaera pantotropha.
Journal of molecular biology 1993;232(4):1211-2.
1993: Vilmos Fülöp; R Little; A Thompson; C Greenwood; Janos Hajdu
Crystallization and preliminary X-ray analysis of the di-haem cytochrome c peroxidase from Pseudomonas aeruginosa.
Journal of molecular biology 1993;232(4):1208-10.
1993: Frédéric Vellieux; Janos Hajdu; Christophe Verlinde; H Groendijk; Randy J Read; Trevor J Greenhough; J W Campbell; Kor H Kalk; Jennifer A Littlechild; H C Watson
Structure of glycosomal glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma brucei determined from Laue data.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(6):2355-9.
1993: Janos Hajdu
Fast crystallography and time-resolved structures.
Annual review of biophysics and biomolecular structure 1993;22():467-98.
1991: E M Duke; A Hadfield; J L Martin; Ian J Clifton; Janos Hajdu; Louise N Johnson; Gordon P Reid; David R Trentham; I Bruce; George W J Fleet
Towards time-resolved diffraction studies with glycogen phosphorylase.
Ciba Foundation symposium 1991;161():75-86; discussion 86-90.
1990: J W Campbell; Ian J Clifton; Trevor J Greenhough; Janos Hajdu; S C Harrison; R C Liddington; A K Shrive
Calcium binding sites in tomato bushy stunt virus visualized by Laue crystallography.
Journal of molecular biology 1990;214(3):627-32.
1990: Janos Hajdu; Louise N Johnson
Progress with Laue diffraction studies on protein and virus crystals.
Biochemistry 1990;29(7):1669-78.
1989: Janos Hajdu; Trevor J Greenhough; Ian J Clifton; J W Campbell; A K Shrive; S C Harrison; R C Liddington
Laue crystallography: application to virus crystals.
Basic life sciences 1989;51():331-9.
1988: David Barford; J W Schwabe; Nikos G Oikonomakos; K Ravi Acharya; Janos Hajdu; Anastassios C Papageorgiou; J L Martin; J C Knott; A Vasella; Louise N Johnson
Channels at the catalytic site of glycogen phosphorylase b: binding and kinetic studies with the beta-glycosidase inhibitor D-gluconohydroximo-1,5-lactone N-phenylurethane.
Biochemistry 1988;27(18):6733-41.
1987: Nikos G Oikonomakos; Louise N Johnson; K Ravi Acharya; David I Stuart; David Barford; Janos Hajdu; K M Varvill; A E Melpidou; T Papageorgiou; D J Graves
Pyridoxal phosphate site in glycogen phosphorylase b: structure in native enzyme and in three derivatives with modified cofactors.
Biochemistry 1987;26(25):8381-9.
1987: Louise N Johnson; K Ravi Acharya; David I Stuart; David Barford; Nikos G Oikonomakos; Janos Hajdu; K M Varvill
Phosphate-recognition sites in catalysis and control of glycogen phosphorylase b.
Biochemical Society transactions 1987;15(5):1001-5.
1987: Janos Hajdu; P A Machin; J W Campbell; Trevor J Greenhough; Ian J Clifton; S Zurek; S Gover; Louise N Johnson; M Elder
Millisecond X-ray diffraction and the first electron density map from Laue photographs of a protein crystal.
Nature 1987;329(6135):178-81.