FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Frances Hakim

Research Profile

Anatomy

Living Beings

Procedures

Concepts & Ideas

T-Lymphocyte Subsets

Disorders

Chemicals & Drugs

Physiology

Co-author Network

Publications

TOP 3
Daniel H Fowler; Juan Gea-Banacloche; Andre Goy; Ronald E Gress; Frances T Hakim; David C Halverson; Nancy M Hardy; Dennis D Hickstein; Carl H June; Hanh M Khuu; Robert Korngold; Susan F Leitman; Bruce L Levine; Jacopo Mariotti; Miriam Mossoba; Steven Z Pavletic; Andrew L Pecora; Scott Rowley; Marianna Sabatino; Claude Sportes; Seth M Steinberg; David Stroncek; Luciano Castiello; Michele Donato; Michael Bishop
Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation.
Nancy M Hardy; Carl H June; Hanh M Khuu; Roger J Kurlander; Bruce L Levine; Sarfraz Memon; Esther Mena; Jeanne Odom; Stefania Pittaluga; Ran Reshef; Jeremy J Rose; Seth M Steinberg; Maryalice Stetler-Stevenson; Robert H Vonderheide; Bazetta Blacklock-Schuver; Andrew J Dwyer; Vicki Fellowes; Daniel H Fowler; Ronald E Gress; Frances T Hakim; Daniele N Avila; Michael Bishop
Costimulated tumor-infiltrating lymphocytes are a feasible and safe alternative donor cell therapy for relapse after allogeneic stem cell transplantation.
Diana K Lee; Frances T Hakim; Ronald E Gress
The thymus and the immune system: layered levels of control.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Frances Hakim (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Daniel H Fowler; Juan Gea-Banacloche; Andre Goy; Ronald E Gress; Frances T Hakim; David C Halverson; Nancy M Hardy; Dennis D Hickstein; Carl H June; Hanh M Khuu; Robert Korngold; Susan F Leitman; Bruce L Levine; Jacopo Mariotti; Miriam Mossoba; Steven Z Pavletic; Andrew L Pecora; Scott Rowley; Marianna Sabatino; Claude Sportes; Seth M Steinberg; David Stroncek; Luciano Castiello; Michele Donato; Michael Bishop
Phase 2 clinical trial of rapamycin-resistant donor CD4+ Th2/Th1 (T-Rapa) cells after low-intensity allogeneic hematopoietic cell transplantation.
Blood 2013;121(15):2864-74.
2012: Nancy M Hardy; Carl H June; Hanh M Khuu; Roger J Kurlander; Bruce L Levine; Sarfraz Memon; Esther Mena; Jeanne Odom; Stefania Pittaluga; Ran Reshef; Jeremy J Rose; Seth M Steinberg; Maryalice Stetler-Stevenson; Robert H Vonderheide; Bazetta Blacklock-Schuver; Andrew J Dwyer; Vicki Fellowes; Daniel H Fowler; Ronald E Gress; Frances T Hakim; Daniele N Avila; Michael Bishop
Costimulated tumor-infiltrating lymphocytes are a feasible and safe alternative donor cell therapy for relapse after allogeneic stem cell transplantation.
Blood 2012;119(12):2956-9.
2010: Diana K Lee; Frances T Hakim; Ronald E Gress
The thymus and the immune system: layered levels of control.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer 2010;5(10 Suppl 4):S273-6.
2010: Matin M Imanguli; Jane C Atkinson; Sandra A Mitchell; Daniele N Avila; Rachel J Bishop; Edward W Cowen; Manuel B Datiles; Frances T Hakim; David E Kleiner; Michael C Krumlauf; Steven Z Pavletic
Salivary gland involvement in chronic graft-versus-host disease: prevalence, clinical significance, and recommendations for evaluation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2010;16(10):1362-9.
2010: Claude Sportès; Rebecca R. Babb; Michael C Krumlauf; Frances T Hakim; Seth M Steinberg; Catherine K Chow; Margaret R Brown; Thomas A Fleisher; Pierre Noel; Irina Maric; Maryalice Stetler-Stevenson; Julie Engel; Renaud Buffet; Michel MORRE; Robert J Amato; Andrew L Pecora; CRYSTAL MACKALL; Ronald E Gress
Phase I study of recombinant human interleukin-7 administration in subjects with refractory malignancy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(2):727-35.
2009: Frances T Hakim
TRECing long-term success in SCID.
Blood 2009;114(7):1287-8.
2009: Veena Kapoor; Frances T Hakim; Najibah Rehman; Ronald E Gress; William G Telford
Quantum dots thermal stability improves simultaneous phenotype-specific telomere length measurement by FISH-flow cytometry.
Journal of immunological methods 2009;344(1):6-14.
2009: Matin M Imanguli; William D Swaim; Stacy C League; Ronald E Gress; Steven Z Pavletic; Frances T Hakim
Increased T-bet+ cytotoxic effectors and type I interferon-mediated processes in chronic graft-versus-host disease of the oral mucosa.
Blood 2009;113(15):3620-30.
2008: Robert M Dean; Terry J Fry; CRYSTAL MACKALL; Seth M Steinberg; Frances T Hakim; Daniel Fowler; Jeanne Odom; Jason Foley; Ronald E Gress; Michael Bishop
Association of serum interleukin-7 levels with the development of acute graft-versus-host disease.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(35):5735-41.
2008: Claude Sportès; Frances T Hakim; Sarfraz A Memon; Hua Zhang; Kevin S Chua; Margaret R Brown; Thomas A Fleisher; Michael C Krumlauf; Rebecca R. Babb; Catherine K Chow; Terry J Fry; Julie Engels; Renaud Buffet; Michel MORRE; Robert J Amato; David J Venzon; Robert Korngold; Andrew L Pecora; Ronald E Gress; CRYSTAL MACKALL
Administration of rhIL-7 in humans increases in vivo TCR repertoire diversity by preferential expansion of naive T cell subsets.
The Journal of experimental medicine 2008;205(7):1701-14.
2008: Michael Boyiadzis; Sarfraz A Memon; Jesse Carson; Kenton Allen; Miroslaw J Szczepanski; Barbara A Vance; Robert Dean; Michael Bishop; Ronald E Gress; Frances T Hakim
Up-regulation of NK cell activating receptors following allogeneic hematopoietic stem cell transplantation under a lymphodepleting reduced intensity regimen is associated with elevated IL-15 levels.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2008;14(3):290-300.
2007: Kirsten M Williams; Frances T Hakim; Ronald E Gress
T cell immune reconstitution following lymphodepletion.
Seminars in immunology 2007;19(5):318-30.
2007: Nancy M Hardy; Frances T Hakim; Seth M Steinberg; Michael Krumlauf; Romana Cvitkovic; Rebecca R. Babb; Jeanne Odom; Daniel H Fowler; Ronald E Gress; Michael Bishop
Host T cells affect donor T cell engraftment and graft-versus-host disease after reduced-intensity hematopoietic stem cell transplantation.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2007;13(9):1022-30.
2007: Frances T Hakim; Ronald E Gress
Immunosenescence: deficits in adaptive immunity in the elderly.
Tissue antigens 2007;70(3):179-89.
2007: Frances T Hakim; Ronald E Gress
Thymic involution: implications for self-tolerance.
Methods in molecular biology (Clifton, N.J.) 2007;380():377-90.
2006: Philip J Lucas; Seong-Jin Kim; CRYSTAL MACKALL; William G Telford; Yu-Waye Chu; Frances T Hakim; Ronald E Gress
Dysregulation of IL-15-mediated T-cell homeostasis in TGF-beta dominant-negative receptor transgenic mice.
Blood 2006;108(8):2789-95.
2005: Frances T Hakim; Ronald E Gress
Reconstitution of the lymphocyte compartment after lymphocyte depletion: a key issue in clinical immunology.
European journal of immunology 2005;35(11):3099-102.
2005: Frances T Hakim; Ronald E Gress
Immunosenescence: immune deficits in the elderly and therapeutic strategies to enhance immune competence.
Expert review of clinical immunology 2005;1(3):443-58.
2005: Sattva S Neelapu; Larry W Kwak; CAROL KOBRIN; Craig W Reynolds; John Janik; Kieron Dunleavy; Therese White; Linda Harvey; Robin Pennington; Maryalice Stetler-Stevenson; Elaine S Jaffe; Seth M Steinberg; Ronald E Gress; Frances T Hakim; Wyndham H Wilson
Vaccine-induced tumor-specific immunity despite severe B-cell depletion in mantle cell lymphoma.
Nature medicine 2005;11(9):986-91.
2005: Kieron Dunleavy; Frances T Hakim; Hyun Kyung Kim; John Janik; Nicole Grant; Takayuki Nakayama; Therese White; George Wright; Larry W Kwak; Ronald E Gress; Giovanna Tosato; Wyndham H Wilson
B-cell recovery following rituximab-based therapy is associated with perturbations in stromal derived factor-1 and granulocyte homeostasis.
Blood 2005;106(3):795-802.
2005: Claude Sportès; Nicole J McCarthy; Frances T Hakim; Seth M Steinberg; David J Liewehr; David Weng; Shivaani Kummar; Juan Gea-Banacloche; Catherine K Chow; Robert M Dean; Kathleen Castro; Donna Marchigiani; Michael Bishop; Daniel H Fowler; Ronald E Gress
Establishing a platform for immunotherapy: clinical outcome and study of immune reconstitution after high-dose chemotherapy with progenitor cell support in breast cancer patients.
Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation 2005;11(6):472-83.
2005: Qing Lan; Luoping Zhang; Frances T Hakim; Min Shen; Sarfraz A Memon; Guilan Li; Roel Vermeulen; Martyn T Smith; Stephen M Rappaport; Richard Hayes; Martha Linet; Songnian Yin; Nathaniel Rothman; Charles S Rabkin
Lymphocyte toxicity and T cell receptor excision circles in workers exposed to benzene.
Chemico-biological interactions 2005;153-154():111-5.
2005: Frances T Hakim; Sarfraz A Memon; Rosemarie Cepeda; Elizabeth C Jones; Catherine K Chow; Claude Kasten-Sportes; Jeanne Odom; Barbara A Vance; Barbara L Christensen; CRYSTAL MACKALL; Ronald E Gress
Age-dependent incidence, time course, and consequences of thymic renewal in adults.
The Journal of clinical investigation 2005;115(4):930-9.
2005: Paolo A Muraro; Daniel C Douek; Dubinsky N Amy; Katherine Chung; F Javier Guenaga; Riccardo Cassiani Ingoni; Catherine Campbell; Sarfraz A Memon; James W Nagle; Frances T Hakim; Ronald E Gress; Henry McFarland; Richard K Burt; Roland Martin
Thymic output generates a new and diverse TCR repertoire after autologous stem cell transplantation in multiple sclerosis patients.
The Journal of experimental medicine 2005;201(5):805-16.
2004: Michael Bishop; Seth M Steinberg; Ronald E Gress; Nancy M Hardy; Donna Marchigiani; Claude Kasten-Sportes; Robert Dean; Steven Z Pavletic; Juan Gea-Banacloche; Kathleen Castro; Frances T Hakim; Michael Krumlauf; Elizabeth J Read; Charles Carter; Susan F Leitman; Daniel H Fowler
Targeted pretransplant host lymphocyte depletion prior to T-cell depleted reduced-intensity allogeneic stem cell transplantation.
British journal of haematology 2004;126(6):837-43.
2004: Yu-Waye Chu; Sarfraz A Memon; Susan O Sharrow; Frances T Hakim; Michael Eckhaus; Philip J Lucas; Ronald E Gress
Exogenous IL-7 increases recent thymic emigrants in peripheral lymphoid tissue without enhanced thymic function.
Blood 2004;104(4):1110-9.
2004: Kouhei Yamashita; Uimook Choi; Patricia C Woltz; Susan F Foster; michael sneller; Frances T Hakim; Daniel H Fowler; Michael Bishop; Steven Z Pavletic; Marisa Tamari; Kathleen Castro; A John Barrett; Richard W Childs; Gabor G Illei; Susan F Leitman; Harry L Malech; Mitchell E Horwitz
Severe chronic graft-versus-host disease is characterized by a preponderance of CD4(+) effector memory cells relative to central memory cells.
Blood 2004;103(10):3986-8.
2004: Frances T Hakim; Francis A Flomerfelt; Michael Boyiadzis; Ronald E Gress
Aging, immunity and cancer.
Current opinion in immunology 2004;16(2):151-6.
2002: Frances T Hakim; Ronald E Gress
Reconstitution of thymic function after stem cell transplantation in humans.
Current opinion in hematology 2002;9(6):490-6.
2002: D Fowler; J Hou; Jason Foley; Frances T Hakim; Jeanne Odom; Kathleen Castro; Charles Carter; Elizabeth J Read; Juan Gea-Banacloche; Claude Kasten-Sportes; Larry W Kwak; W Wilson; B Levine; Carl H June; Ronald E Gress; Michael Bishop
Phase I clinical trial of donor T-helper type-2 cells after immunoablative, reduced intensity allogeneic PBSC transplant.
Cytotherapy 2002;4(5):429-30.
2001: Frances T Hakim; Daniel H Fowler; Gene M Shearer; Ronald E Gress
Animal models of acute and chronic graft-versus-host disease.
Current protocols in immunology / edited by John E. Coligan ... [et al.] 2001;Chapter 4():Unit 4.3.
2000: CRYSTAL MACKALL; D Stein; T A Fleisher; M R Brown; Frances T Hakim; Catherine V Bare; Susan F Leitman; Elizabeth J Read; C S Carter; Leonard H Wexler; Ronald E Gress
Prolonged CD4 depletion after sequential autologous peripheral blood progenitor cell infusions in children and young adults.
Blood 2000;96(2):754-62.
2000: Jo Anne Zujewski; ID Horak; CJ Bol; R Woestenborghs; Charlie Bowden; David W End; V K Piotrovsky; J Chiao; Robert T Belly; A Todd; William Kopp; David R Kohler; Catherine Chow; MH Noone; Frances T Hakim; G Larkin; Ronald E Gress; Robert B Nussenblatt; A B Kremer; Kenneth H Cowan
Phase I and pharmacokinetic study of farnesyl protein transferase inhibitor R115777 in advanced cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2000;18(4):927-41.
1998: C Rohlff; M V Blagosklonny; E Kyle; A Kesari; I Y Kim; D J Zelner; Frances T Hakim; Jane Trepel; Raymond C Bergan
Prostate cancer cell growth inhibition by tamoxifen is associated with inhibition of protein kinase C and induction of p21(waf1/cip1).
The Prostate 1998;37(1):51-9.
1997: CRYSTAL MACKALL; Frances T Hakim; Ronald E Gress
Restoration of T-cell homeostasis after T-cell depletion.
Seminars in immunology 1997;9(6):339-46.
1997: Frances T Hakim; R Cepeda; S Kaimei; CRYSTAL MACKALL; N McAtee; Jo Anne Zujewski; Kenneth H Cowan; Ronald E Gress
Constraints on CD4 recovery postchemotherapy in adults: thymic insufficiency and apoptotic decline of expanded peripheral CD4 cells.
Blood 1997;90(9):3789-98.
1997: A W Tolcher; Joyce A O'Shaughnessy; R B Weiss; Jo Anne Zujewski; R C Myhand; E Schneider; Frances T Hakim; Ronald E Gress; Barry Goldspiel; MH Noone; L R Brewster; M R Gossard; Kenneth H Cowan
A phase I study of topotecan followed sequentially by doxorubicin in patients with advanced malignancies.
Clinical cancer research : an official journal of the American Association for Cancer Research 1997;3(5):755-60.
1997: CRYSTAL MACKALL; Frances T Hakim; Ronald E Gress
T-cell regeneration: all repertoires are not created equal.
Immunology today 1997;18(5):245-51.
1996: Frances T Hakim; R Childs; J Balow; Kenneth H Cowan; Jo Anne Zujewski; Ronald E Gress
Development of paroxysmal nocturnal hemoglobinuria after chemotherapy.
Blood 1996;88(12):4725-6.
1996: Raymond C Bergan; Frances T Hakim; Gretchen N Schwartz; E Kyle; R Cepada; J M Szabo; D Fowler; Ronald E Gress; Len Neckers
Electroporation of synthetic oligodeoxynucleotides: a novel technique for ex vivo bone marrow purging.
Blood 1996;88(2):731-41.
1996: Gretchen N Schwartz; Frances T Hakim; Jo Anne Zujewski; J M Szabo; R Cepada; D Riseberg; M K Warren; CRYSTAL MACKALL; A Setzer; MH Noone; Kenneth H Cowan; Joyce A O'Shaughnessy; Ronald E Gress
Early suppressive effects of chemotherapy and cytokine treatment on committed versus primitive haemopoietic progenitors in patient bone marrow.
British journal of haematology 1996;92(3):537-47.
1996: Luiz Vicente Rizzo; P Silver; Barbara Wiggert; Frances T Hakim; R T Gazzinelli; Chi-Chao Chan; Rachel R Caspi
Establishment and characterization of a murine CD4+ T cell line and clone that induce experimental autoimmune uveoretinitis in B10.A mice.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(4):1654-60.
1995: Frances T Hakim; R Cepeda; G S Gray; Carl H June; Ryo Abe
Acute graft-versus-host reaction can be aborted by blockade of costimulatory molecules.
Journal of immunology (Baltimore, Md. : 1950) 1995;155(4):1757-66.
1994: Frances T Hakim; S Payne; Gene M Shearer
Recovery of T cell populations after acute graft-vs-host reaction.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(1):58-64.
1993: Edna Mozes; Leonard D Kohn; Frances T Hakim; dinah singer
Resistance of MHC class I-deficient mice to experimental systemic lupus erythematosus.
Science (New York, N.Y.) 1993;261(5117):91-3.
1993: Mario Clerici; Frances T Hakim; D J Venzon; S Blatt; Craig W Hendrix; T A Wynn; Gene M Shearer
Changes in interleukin-2 and interleukin-4 production in asymptomatic, human immunodeficiency virus-seropositive individuals.
The Journal of clinical investigation 1993;91(3):759-65.
1992: S C Muluk; Frances T Hakim; Gene M Shearer
Regulation of graft-versus-host-reaction by Mlsa-reactive donor T cells.
European journal of immunology 1992;22(8):1967-73.
1991: Frances T Hakim; R T Gazzinelli; Eric Y Denkers; Sara Hieny; Gene M Shearer; Alan Sher
CD8+ T cells from mice vaccinated against Toxoplasma gondii are cytotoxic for parasite-infected or antigen-pulsed host cells.
Journal of immunology (Baltimore, Md. : 1950) 1991;147(7):2310-6.
1991: Frances T Hakim; Susan O Sharrow; S Payne; Gene M Shearer
Repopulation of host lymphohematopoietic systems by donor cells during graft-versus-host reaction in unirradiated adult F1 mice injected with parental lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(7):2108-15.
1991: Alan Sher; R Gazzinelli; Frances T Hakim; Vidal de la Cruz; C Kendall Stover; SL James; E Pearce
Immunization against parasites: bridging the gap between attenuated and non-living vaccines.
Behring Institute Mitteilungen 1991;(88):244-8.
1991: R T Gazzinelli; Frances T Hakim; Sara Hieny; G M Shearer; Alan Sher
Synergistic role of CD4+ and CD8+ T lymphocytes in IFN-gamma production and protective immunity induced by an attenuated Toxoplasma gondii vaccine.
Journal of immunology (Baltimore, Md. : 1950) 1991;146(1):286-92.
1990: S C Muluk; Frances T Hakim; Gene M Shearer
Murine cytomegalovirus infection can enhance hybrid resistance through modulation of host natural killer activity.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(4):1113-9.
1990: Frances T Hakim; D H Pluznik; Gene M Shearer
Factors contributing to the decrease in concanavalin A-induced colony-stimulating factors in acute suppressive graft-versus-host disorder.
Transplantation 1990;49(4):781-7.
1990: Frances T Hakim; D H Pluznik; Gene M Shearer
Alterations in T cell-derived colony-stimulating factors associated with GVH-induced immune deficiency.
Transplantation 1990;49(4):773-81.