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Christine Hale

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Derek Pickard; Karthikeyan Sivaraman; Keith Turner; Michael Wetter; Christine Hale; Robert A Kingsley; Gemma Langridge; Gordon Dougan
A genomewide mutagenesis screen identifies multiple genes contributing to Vi capsular expression in Salmonella enterica serovar Typhi.
Simon Clare; Cei Abreu-Goodger; Anton J Enright; Gadi Frankel; David Goulding; Christine Hale; Jennifer L Hill; Victoria John; Trevor D Lawley; Pietro Mastroeni; Elena Vigorito; Alan W Walker; Gordon Dougan
Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice.
Anastasia Nijnik; Claire Raisen; Ramiro Ramirez-Solis; Edward Ryder; Karen P Steel; Jacqueline K White; Mark Lucas; Lynda Mottram; Niels C Adams; Hibret Adissu; Jing Chen; Simon Clare; Gordon Dougan; Jeanne Estabel; Christine Hale; Robert E W Hancock
The role of sphingosine-1-phosphate transporter Spns2 in immune system function.

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2013: Derek Pickard; Karthikeyan Sivaraman; Keith Turner; Michael Wetter; Christine Hale; Robert A Kingsley; Gemma Langridge; Gordon Dougan
A genomewide mutagenesis screen identifies multiple genes contributing to Vi capsular expression in Salmonella enterica serovar Typhi.
Journal of bacteriology 2013;195(6):1320-6.
2013: Simon Clare; Cei Abreu-Goodger; Anton J Enright; Gadi Frankel; David Goulding; Christine Hale; Jennifer L Hill; Victoria John; Trevor D Lawley; Pietro Mastroeni; Elena Vigorito; Alan W Walker; Gordon Dougan
Enhanced susceptibility to Citrobacter rodentium infection in microRNA-155-deficient mice.
Infection and immunity 2013;81(3):723-32.
2012: Anastasia Nijnik; Claire Raisen; Ramiro Ramirez-Solis; Edward Ryder; Karen P Steel; Jacqueline K White; Mark Lucas; Lynda Mottram; Niels C Adams; Hibret Adissu; Jing Chen; Simon Clare; Gordon Dougan; Jeanne Estabel; Christine Hale; Robert E W Hancock
The role of sphingosine-1-phosphate transporter Spns2 in immune system function.
Journal of immunology (Baltimore, Md. : 1950) 2012;189(1):102-11.
2012: Anastasia Nijnik; Christine Podrini; Claire Raisen; Ramiro Ramirez-Solis; Jacqui K White; Kosuke Yusa; David J Adams; Niels Adams; Simon Clare; Jeanne Estabel; Aaron R Everitt; David Goulding; Christine Hale; Robert E W Hancock; Mark Lucas; Rebecca E McIntyre; Lynda Mottram; Gordon Dougan
The critical role of histone H2A-deubiquitinase Mysm1 in hematopoiesis and lymphocyte differentiation.
Blood 2012;119(6):1370-9.
2012: Raffaella Rossi; Zarah Abdellah; Robert Andrews; Paul J Fairchild; David Goulding; Christine Hale; Gordon Dougan
Interaction of Salmonella typhimurium with dendritic cells derived from pluripotent embryonic stem cells.
PloS one 2012;7(12):e52232.
2011: Wei Wang; Jun Yu; Allan Bradley; Anne Dell; David Goulding; Christine Hale; Stuart M Haslam; Christopher Lindsay; Stephen Michell; Raffaella Rossi; Bérangère Tissot; Rick Titball; Ana Toribio; Gordon Dougan
Mannosidase 2, alpha 1 deficiency is associated with ricin resistance in embryonic stem (ES) cells.
PloS one 2011;6(8):e22993.
2009: Lindsay Hall; Simon Clare; Derek Pickard; Simon O Clark; Dominic L F Kelly; Moataz Abd El Ghany; Christine Hale; Jes Dietrich; Peter Andersen; Philip D Marsh; Gordon Dougan
Characterisation of a live Salmonella vaccine stably expressing the Mycobacterium tuberculosis Ag85B-ESAT6 fusion protein.
Vaccine 2009;27(49):6894-904.
2009: Jun Yu; Raffaella Rossi; Christine Hale; David Goulding; Gordon Dougan
Interaction of enteric bacterial pathogens with murine embryonic stem cells.
Infection and immunity 2009;77(2):585-97.
2006: Maha Jomaa; Stephen James Terry; Christine Hale; Christopher Jones; Gordon Dougan; Jeremy Brown
Immunization with the iron uptake ABC transporter proteins PiaA and PiuA prevents respiratory infection with Streptococcus pneumoniae.
Vaccine 2006;24(24):5133-9.
2006: Christine Hale; Frances Bowe; Derek Pickard; Simon Clare; Jean-François Haeuw; Ultan Powers; Nathalie Menager; Pietro Mastroeni; Gordon Dougan
Evaluation of a novel Vi conjugate vaccine in a murine model of salmonellosis.
Vaccine 2006;24(20):4312-20.
2004: Christine Hale; Ian R Humphreys; Tracy Hussell; Frances Bowe; Simon Clare; Derek Pickard; Andrew Preston; Giuseppe Del Giudice; Gordon Dougan
Mucosal immunisation of murine neonates using whole cell and acellular Pertussis vaccines.
Vaccine 2004;22(27-28):3595-602.
2004: Nicola D Mckelvie; Richard Stratford; Tao Wu; Trevor Bellaby; Emma Aldred; Nicky Hughes; Steven N Chatfield; Derek Pickard; Christine Hale; Gordon Dougan; Shahid A Khan
Expression of heterologous antigens in Salmonella Typhimurium vaccine vectors using the in vivo-inducible, SPI-2 promoter, ssaG.
Vaccine 2004;22(25-26):3243-55.
2004: Frances Bowe; E C Lavelle; Edel A McNeela; Christine Hale; Simon Clare; Beatrice Arico; Marzia M Giuliani; Aaron Rae; Alan Huett; Rino Rappuoli; Gordon Dougan; Kingston H G Mills
Mucosal vaccination against serogroup B meningococci: induction of bactericidal antibodies and cellular immunity following intranasal immunization with NadA of Neisseria meningitidis and mutants of Escherichia coli heat-labile enterotoxin.
Infection and immunity 2004;72(7):4052-60.
2003: Simon Clare; Robert Goldin; Christine Hale; Richard Aspinall; Cameron Simmons; Pietro Mastroeni; Gordon Dougan
Intracellular adhesion molecule 1 plays a key role in acquired immunity to salmonellosis.
Infection and immunity 2003;71(10):5881-91.
2003: Michael Box; Deborah A Parks; Andrew Knight; Christine Hale; Paul S Fishman; Neil Fairweather
A multi-domain protein system based on the HC fragment of tetanus toxin for targeting DNA to neuronal cells.
Journal of drug targeting 2003;11(6):333-43.
2002: Stephen Reece; Cameron P Simmons; Robert J Fitzhenry; Marjan Ghaem-Maghami; Rosanna Mundy; Christine Hale; Stephen Matthews; Gordon Dougan; Alan D Phillips; Gad Frankel
Tyrosine residues at the immunoglobulin-C-type lectin inter-domain boundary of intimin are not involved in Tir-binding but implicated in colonisation of the host.
Microbes and infection / Institut Pasteur 2002;4(14):1389-99.
2002: Stephen Reece; Cameron P Simmons; Robert J Fitzhenry; Miranda Batchelor; Christine Hale; Stephen Matthews; Alan D Phillips; Gordon Dougan; Gad Frankel
Mutagenesis of conserved tryptophan residues within the receptor-binding domain of intimin: influence on binding activity and virulence.
Microbiology (Reading, England) 2002;148(Pt 3):657-65.
2000: Elizabeth L Hartland; Sarah Daniell; Robin M Delahay; Bianca C Neves; Timothy S Wallis; Robert K Shaw; Christine Hale; Stuart Knutton; Gad Frankel
The type III protein translocation system of enteropathogenic Escherichia coli involves EspA-EspB protein interactions.
Molecular microbiology 2000;35(6):1483-92.
1999: Elizabeth L Hartland; Miranda Batchelor; Robin M Delahay; Christine Hale; Stephen Matthews; Gordon Dougan; Stuart Knutton; Ian F Connerton; Gad Frankel
Binding of intimin from enteropathogenic Escherichia coli to Tir and to host cells.
Molecular microbiology 1999;32(1):151-8.