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Ian Hall

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TOP 3
Ian P Hall
Stratified medicine: drugs meet genetics.
Charlotte K Billington; Ian P Hall
Novel cAMP signalling paradigms: therapeutic implications for airway disease.
M E Roberts; L Magowan; Ian P Hall; Simon R Johnson
Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production.

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All Publications

2013: Ian P Hall
Stratified medicine: drugs meet genetics.
European respiratory review : an official journal of the European Respiratory Society 2013;22(127):53-7.
2012: Charlotte K Billington; Ian P Hall
Novel cAMP signalling paradigms: therapeutic implications for airway disease.
British journal of pharmacology 2012;166(2):401-10.
2011: M E Roberts; L Magowan; Ian P Hall; Simon R Johnson
Discoidin domain receptor 1 regulates bronchial epithelial repair and matrix metalloproteinase production.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2011;37(6):1482-93.
2011: Ma'en Obeidat; Ian P Hall
Genetics of complex respiratory diseases: implications for pathophysiology and pharmacology studies.
British journal of pharmacology 2011;163(1):96-105.
2011: Charlotte K Billington; Ian P Hall
Real time analysis of β(2)-adrenoceptor-mediated signaling kinetics in human primary airway smooth muscle cells reveals both ligand and dose dependent differences.
Respiratory research 2011;12():89.
2011: Yize I Wan; David P Strachan; David M Evans; John Henderson; Tricia McKeever; John W Holloway; Ian P Hall; Ian Sayers
A genome-wide association study to identify genetic determinants of atopy in subjects from the United Kingdom.
The Journal of allergy and clinical immunology 2011;127(1):223-31, 231.e1-3.
2010: Ian P Hall; David A Lomas
The genetics of obstructive lung disease: big is beautiful.
Thorax 2010;65(9):760-1.
2010: Shailendra R Singh; Charlotte K Billington; Ian Sayers; Ian P Hall
Can lineage-specific markers be identified to characterize mesenchyme-derived cell populations in the human airways?
American journal of physiology. Lung cellular and molecular physiology 2010;299(2):L169-83.
2010: Bo Liu; Samantha E Peel; Jane Fox; Ian P Hall
Reverse mode Na+/Ca2+ exchange mediated by STIM1 contributes to Ca2+ influx in airway smooth muscle following agonist stimulation.
Respiratory research 2010;11():168.
2009: Nathalie P Duroudier; David P Strachan; John D Blakey; Ian P Hall
Association of the cysteinyl leukotriene receptor 1 gene with atopy in the British 1958 birth cohort.
The Journal of allergy and clinical immunology 2009;124(3):566-72, 572.e1-3.
2009: Ian Sayers; J Hawley; C E Stewart; Charlotte K Billington; A Henry; J R Leighton-Davies; S J Charlton; Ian P Hall
Pharmacogenetic characterization of indacaterol, a novel beta 2-adrenoceptor agonist.
British journal of pharmacology 2009;158(1):277-86.
2009: Ian P Hall
How will genetic approaches assist in the management of respiratory diseases?
Current opinion in pharmacology 2009;9(3):256-61.
2009: John D Blakey; Ian Sayers; Susan M Ring; David P Strachan; Ian P Hall
Positionally cloned asthma susceptibility gene polymorphisms and disease risk in the British 1958 Birth Cohort.
Thorax 2009;64(5):381-7.
2009: Ceri E Stewart; Ian P Hall; Stuart Parker; Miriam F Moffat; Andrew J Wardlaw; Martin J Connolly; Charlotte Ruse; Ian Sayers
PLAUR polymorphisms and lung function in UK smokers.
BMC medical genetics 2009;10():112.
2008: Samantha E Peel; Bo Liu; Ian P Hall
ORAI and store-operated calcium influx in human airway smooth muscle cells.
American journal of respiratory cell and molecular biology 2008;38(6):744-9.
2008: Samuel Denham; Gerard H Koppelman; John Blakey; Matthias Wjst; Manuel A Ferreira; Ian P Hall; Ian Sayers
Meta-analysis of genome-wide linkage studies of asthma and related traits.
Respiratory research 2008;9():38.
2008: Shailendra R Singh; Ian P Hall
Airway myofibroblasts and their relationship with airway myocytes and fibroblasts.
Proceedings of the American Thoracic Society 2008;5(1):127-32.
2008: Charlotte K Billington; Ivan R Le Jeune; Kenneth W Young; Ian P Hall
A major functional role for phosphodiesterase 4D5 in human airway smooth muscle cells.
American journal of respiratory cell and molecular biology 2008;38(1):1-7.
2007: Ian P Hall; Ian Sayers
Pharmacogenetics and asthma: false hope or new dawn?
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2007;29(6):1239-45.
2007: Bo Liu; Anette M Freyer; Ian P Hall
Bradykinin activates calcium-dependent potassium channels in cultured human airway smooth muscle cells.
American journal of physiology. Lung cellular and molecular physiology 2007;292(4):L898-907.
2007: Natalie Smith; Claudia A Browning; Nathalie Duroudier; Ceri Stewart; Samantha Peel; Caroline Swan; Ian P Hall; Ian Sayers
Salmeterol and cytokines modulate inositol-phosphate signalling in human airway smooth muscle cells via regulation at the receptor locus.
Respiratory research 2007;8():68.
2007: Nathalie P Duroudier; Ian Sayers; Charlotte Carabott Castagna; Anthony G Fenech; Eva Halapi; Caroline Swan; Ian P Hall
Functional polymorphism and differential regulation of CYSLTR1 transcription in human airway smooth muscle and monocytes.
Cell biochemistry and biophysics 2007;47(1):119-30.
2006: Ian P Hall
Pharmacogenetics of asthma.
Chest 2006;130(6):1873-8.
2006: Ian P Hall; John D Blakey; Khalid A Al-Balushi; Amanda Henry; Ian Sayers; Marcus E Pembrey; Susan M Ring; Wendy L McArdle; David P Strachan
Beta2-adrenoceptor polymorphisms and asthma from childhood to middle age in the British 1958 birth cohort: a genetic association study.
Lancet 2006;368(9537):771-9.
2006: J A Clayton; Ivan R Le Jeune; Ian P Hall
Severe hyponatraemia in medical in-patients: aetiology, assessment and outcome.
QJM : monthly journal of the Association of Physicians 2006;99(8):505-11.
2006: Samuel J Wadsworth; Hala S Nijmeh; Ian P Hall
Glucocorticoids increase repair potential in a novel in vitro human airway epithelial wounding model.
Journal of clinical immunology 2006;26(4):376-87.
2006: Caroline Swan; Susan A Richards; Nathalie P Duroudier; Ian Sayers; Ian P Hall
Alternative promoter use and splice variation in the human histamine H1 receptor gene.
American journal of respiratory cell and molecular biology 2006;35(1):118-26.
2006: Martin Horan; Vicky Newsway; Mark D Lewis; Tammy E Easter; D Aled Rees; Arti Mahto; David S Millar; Annie M Procter; Maurice F Scanlon; Ian B Wilkinson; Ian P Hall; Amanda Henry; John D Blakey; Philip Bath; John R Cockcroft; Michael Krawczak; David N Cooper
Genetic variation at the growth hormone (GH1) and growth hormone receptor (GHR) loci as a risk factor for hypertension and stroke.
Human genetics 2006;119(5):527-40.
2006: Niamh Durcan; Richard W Costello; W Graham McLean; Jan Krzysztof Blusztajn; Beata Madziar; Anthony G Fenech; Ian P Hall; Gerald J Gleich; Lorcan McGarvey; Marie-Therese Walsh
Eosinophil-mediated cholinergic nerve remodeling.
American journal of respiratory cell and molecular biology 2006;34(6):775-86.
2006: Ian Sayers; Caroline Swan; Ian P Hall
The effect of beta2-adrenoceptor agonists on phospholipase C (beta1) signalling in human airway smooth muscle cells.
European journal of pharmacology 2006;531(1-3):9-12.
2006: Samantha E Peel; Bo Liu; Ian P Hall
A key role for STIM1 in store operated calcium channel activation in airway smooth muscle.
Respiratory research 2006;7():119.
2006: J A Clayton; S Rodgers; John D Blakey; Anthony J Avery; Ian P Hall
Thiazide diuretic prescription and electrolyte abnormalities in primary care.
British journal of clinical pharmacology 2006;61(1):87-95.
2005: Gareth Goh; Tim Self; Maria D Barbadillo Muñoz; Ian P Hall; Lorraine Young; Chris Denning
Molecular and phenotypic analyses of human embryonic stem cell-derived cardiomyocytes: opportunities and challenges for clinical translation.
Thrombosis and haemostasis 2005;94(4):728-37.
2005: Ian P Hall; John D Blakey
Genetic association studies in Thorax.
Thorax 2005;60(5):357-9.
2005: John D Blakey; Eva Halapi; Unnur S Bjornsdottir; Amanda Henry; S Kristinsson; Ruchi Upmanyu; kari stefansson; Hakon Hakonarson; Ian P Hall
Contribution of ADAM33 polymorphisms to the population risk of asthma.
Thorax 2005;60(4):274-6.
2005: Ian Sayers; Ian P Hall
Pharmacogenetic approaches in the treatment of asthma.
Current allergy and asthma reports 2005;5(2):101-8.
2004: Anette M Freyer; Charlotte K Billington; Raymond B Penn; Ian P Hall
Extracellular matrix modulates beta2-adrenergic receptor signaling in human airway smooth muscle cells.
American journal of respiratory cell and molecular biology 2004;31(4):440-5.
2004: Anthony G Fenech; Charlotte K Billington; Caroline Swan; Susan Richards; Therese Hunter; Martin J Ebejer; Alex Felice; Roger Ellul-Micallef; Ian P Hall
Novel polymorphisms influencing transcription of the human CHRM2 gene in airway smooth muscle.
American journal of respiratory cell and molecular biology 2004;30(5):678-86.
2004: Jillian G Baker; Ian P Hall; Stephen J Hill
Temporal characteristics of cAMP response element-mediated gene transcription: requirement for sustained cAMP production.
Molecular pharmacology 2004;65(4):986-98.
2004: Sam J Wadsworth; Anette M Freyer; Randolph L Corteling; Ian P Hall
Biosynthesized matrix provides a key role for survival signaling in bronchial epithelial cells.
American journal of physiology. Lung cellular and molecular physiology 2004;286(3):L596-603.
2004: Randolph L Corteling; Su Li; June Giddings; John Westwick; Chris Poll; Ian P Hall
Expression of transient receptor potential C6 and related transient receptor potential family members in human airway smooth muscle and lung tissue.
American journal of respiratory cell and molecular biology 2004;30(2):145-54.
2004: Ian P Hall
The beta-agonist controversy revisited.
Lancet 2004;363(9404):183-4.
2003: Jillian G Baker; Ian P Hall; Stephen J Hill
Agonist and inverse agonist actions of beta-blockers at the human beta 2-adrenoceptor provide evidence for agonist-directed signaling.
Molecular pharmacology 2003;64(6):1357-69.
2003: Jillian G Baker; Ian P Hall; Stephen J Hill
Influence of agonist efficacy and receptor phosphorylation on antagonist affinity measurements: differences between second messenger and reporter gene responses.
Molecular pharmacology 2003;64(3):679-88.
2003: Jillian G Baker; Ian P Hall; Stephen J Hill
Agonist actions of "beta-blockers" provide evidence for two agonist activation sites or conformations of the human beta1-adrenoceptor.
Molecular pharmacology 2003;63(6):1312-21.
2003: Jillian G Baker; Ian P Hall; Stephen J Hill
Pharmacology and direct visualisation of BODIPY-TMR-CGP: a long-acting fluorescent beta2-adrenoceptor agonist.
British journal of pharmacology 2003;139(2):232-42.
2002: Jillian G Baker; Ian P Hall; Stephen J Hill
Pharmacological characterization of CGP 12177 at the human beta(2)-adrenoceptor.
British journal of pharmacology 2002;137(3):400-8.
2002: Ivan R Le Jeune; Malcolm Shepherd; Gino van Heeke; Miles D Houslay; Ian P Hall
Cyclic AMP-dependent transcriptional up-regulation of phosphodiesterase 4D5 in human airway smooth muscle cells. Identification and characterization of a novel PDE4D5 promoter.
The Journal of biological chemistry 2002;277(39):35980-9.
2002: Stephen J Fowler; Ian P Hall; Andrew M Wilson; Amanda Henry; Brian J Lipworth
5-Lipoxygenase polymorphism and in-vivo response to leukotriene receptor antagonists.
European journal of clinical pharmacology 2002;58(3):187-90.
2002: P C Glynn; E Henney; Ian P Hall
The selective CXCR2 antagonist SB272844 blocks interleukin-8 and growth-related oncogene-alpha-mediated inhibition of spontaneous neutrophil apoptosis.
Pulmonary pharmacology & therapeutics 2002;15(2):103-10.
2002: Anthony G Fenech; Ian P Hall
Pharmacogenetics of asthma.
British journal of clinical pharmacology 2002;53(1):3-15.
2002: Brian J Lipworth; G H Koppelman; Amanda Henry; Ivan R Le Jeune; Wendy J R Coutie; H Meurs; Henk Kauffman; D S Postma; Ian P Hall
Beta2 adrenoceptor promoter polymorphisms: extended haplotypes and functional effects in peripheral blood mononuclear cells.
Thorax 2002;57(1):61-6.
2001: Rodolfo M Pascual; Charlotte K Billington; Ian P Hall; Reynold A Panettieri; James E Fish; Stephen P Peters; Raymond B Penn
Mechanisms of cytokine effects on G protein-coupled receptor-mediated signaling in airway smooth muscle.
American journal of physiology. Lung cellular and molecular physiology 2001;281(6):L1425-35.
2001: Anette M Freyer; S R Johnson; Ian P Hall
Effects of growth factors and extracellular matrix on survival of human airway smooth muscle cells.
American journal of respiratory cell and molecular biology 2001;25(5):569-76.
2001: P C Glynn; E M Henney; Ian P Hall
Peripheral blood neutrophils are hyperresponsive to IL-8 and Gro-alpha in cryptogenic fibrosing alveolitis.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2001;18(3):522-9.
2001: S H Cho; Ian P Hall; Amanda Henry; JC Dewar; D Abraha; J Del Mundo; H Lee; C K Oh
Possible role of the 4G/5G polymorphism of the plasminogen activator inhibitor 1 gene in the development of asthma.
The Journal of allergy and clinical immunology 2001;108(2):212-4.
2001: Charlotte K Billington; R M Pascual; M L Hawkins; Raymond B Penn; Ian P Hall
Interleukin-1beta and rhinovirus sensitize adenylyl cyclase in human airway smooth-muscle cells.
American journal of respiratory cell and molecular biology 2001;24(5):633-9.
2001: Anthony G Fenech; M J Ebejer; Alex Felice; Roger Ellul-Micallef; Ian P Hall
Mutation screening of the muscarinic M(2) and M(3) receptor genes in normal and asthmatic subjects.
British journal of pharmacology 2001;133(1):43-8.
2000: J R Cockcroft; AG Gazis; D J Cross; Amanda Henry; JC Dewar; Ian P Hall; Joe Noon
Beta(2)-adrenoceptor polymorphism determines vascular reactivity in humans.
Hypertension 2000;36(3):371-5.
2000: Ian P Hall
Second messengers, ion channels and pharmacology of airway smooth muscle.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;15(6):1120-7.
2000: Ian P Hall
Pharmacogenetics of asthma.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 2000;15(3):449-51.
2000: Ian P Hall
Interleukin-4 receptor alpha gene variants and allergic disease.
Respiratory research 2000;1(1):6-8.
1999: Charlotte K Billington; Ian P Hall; Stuart J Mundell; Jean-Luc Parent; Reynold A Panettieri; Jeffrey L Benovic; Raymond B Penn
Inflammatory and contractile agents sensitize specific adenylyl cyclase isoforms in human airway smooth muscle.
American journal of respiratory cell and molecular biology 1999;21(5):597-606.
1999: Ian P Hall; Amanda Henry; G Christie; C McDougall; R Hubbard; Peter J Helms
Association of CCR5 delta32 with reduced risk of asthma.
Lancet 1999;354(9186):1264-5.
1999: Mark SCOTT; Caroline Swan; TM Jobson; S Rees; Ian P Hall
Effects of a range of beta2 adrenoceptor agonists on changes in intracellular cyclic AMP and on cyclic AMP driven gene expression in cultured human airway smooth muscle cells.
British journal of pharmacology 1999;128(3):721-9.
1999: Charlotte K Billington; S K Joseph; Caroline Swan; Mark SCOTT; TM Jobson; Ian P Hall
Modulation of human airway smooth muscle proliferation by type 3 phosphodiesterase inhibition.
The American journal of physiology 1999;276(3 Pt 1):L412-9.
1999: Brian J Lipworth; Ian P Hall; I Aziz; KS Tan; Amanda Henry
Beta2-adrenoceptor polymorphism and bronchoprotective sensitivity with regular short- and long-acting beta2-agonist therapy.
Clinical science (London, England : 1979) 1999;96(3):253-9.
1999: Mark SCOTT; Caroline Swan; Amanda Henry; Ian P Hall
Identification of novel polymorphisms within the promoter region of the human beta2 adrenergic receptor gene.
British journal of pharmacology 1999;126(4):841-4.
1999: Brian J Lipworth; Ian P Hall; S Tan; I Aziz; Wendy J R Coutie
Effects of genetic polymorphism on ex vivo and in vivo function of beta2-adrenoceptors in asthmatic patients.
Chest 1999;115(2):324-8.
1999: Ian P Hall
Genetics and pulmonary medicine 8: asthma.
Thorax 1999;54(1):65-9.
1998: Ian P Hall
Genetic factors in asthma severity.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28 Suppl 5():16-20; discussion 26-8.
1998: I Aziz; KS Tan; Ian P Hall; M M Devlin; Brian J Lipworth
Subsensitivity to bronchoprotection against adenosine monophosphate challenge following regular once-daily formoterol.
The European respiratory journal : official journal of the European Society for Clinical Respiratory Physiology 1998;12(3):580-4.
1998: TM Jobson; Charlotte K Billington; Ian P Hall
Regulation of proliferation of human colonic subepithelial myofibroblasts by mediators important in intestinal inflammation.
The Journal of clinical investigation 1998;101(12):2650-7.
1998: Ian P Hall
The genetics of asthma. Candidate gene approaches: gene-environmental interactions.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28 Suppl 1():74-6; discussion 80-1.
1998: JC Dewar; Amanda Henry; A Venn; J F Morrison; J Britton; Ian P Hall
Beta2-adrenoceptor polymorphisms are in linkage disequilibrium, but are not associated with asthma in an adult population.
Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology 1998;28(4):442-8.
1998: I Aziz; Ian P Hall; Lesley C McFarlane; Brian J Lipworth
Beta2-adrenoceptor regulation and bronchodilator sensitivity after regular treatment with formoterol in subjects with stable asthma.
The Journal of allergy and clinical immunology 1998;101(3):337-41.
1998: E Hopes; C McDougall; G Christie; JC Dewar; Amanda Henry; Ian P Hall; Peter J Helms
Association of glutamine 27 polymorphism of beta 2 adrenoceptor with reported childhood asthma: population based study.
BMJ (Clinical research ed.) 1998;316(7132):664.
1997: S Tan; Ian P Hall; J Dewar; Eleanor Dow; Brian J Lipworth
Association between beta 2-adrenoceptor polymorphism and susceptibility to bronchodilator desensitisation in moderately severe stable asthmatics.
Lancet 1997;350(9083):995-9.
1997: JC Dewar; J Wilkinson; Amanda Henry; N S Thomas; IJ Doull; N Morton; P Lio; John F Harvey; Stephen B Liggett; Stephen T Holgate; Ian P Hall
The glutamine 27 beta2-adrenoceptor polymorphism is associated with elevated IgE levels in asthmatic families.
The Journal of allergy and clinical immunology 1997;100(2):261-5.
1997: KS Tan; A Grove; A McLean; Y Gnosspelius; Ian P Hall; Brian J Lipworth
Systemic corticosteriod rapidly reverses bronchodilator subsensitivity induced by formoterol in asthmatic patients.
American journal of respiratory and critical care medicine 1997;156(1):28-35.
1997: JC Dewar; Amanda Henry; J Wilkinson; Stephen T Holgate; N S Thomas; P Lio; N E Morton; Ian P Hall
Association of the Gln 27 beta 2-adrenoceptor polymorphism and IgE variability in asthmatic families.
Chest 1997;111(6 Suppl):78S-79S.
1997: Ian P Hall
The future of asthma.
BMJ (Clinical research ed.) 1997;314(7073):45-9.
1996: E Hardy; M Farahani; Ian P Hall
Regulation of histamine H1 receptor coupling by dexamethasone in human cultured airway smooth muscle.
British journal of pharmacology 1996;118(4):1079-84.
1996: Ian P Hall; Amanda Henry; JC Dewar; J Wilkinson; J Morrison
Fc epsilon RI-beta polymorphisms unlikely to contribute substantially to genetic risk of allergic disease.
BMJ (Clinical research ed.) 1996;312(7026):311.
1996: Ian P Hall
Beta 2-adrenoceptor polymorphisms and asthma.
Monographs in allergy 1996;33():153-67.
1995: Reynold A Panettieri; Ian P Hall; C S Maki; R K Murray
alpha-Thrombin increases cytosolic calcium and induces human airway smooth muscle cell proliferation.
American journal of respiratory cell and molecular biology 1995;13(2):205-16.
1995: Ian P Hall; Amanda Henry; P Wilding; Stephen B Liggett
Association of Glu 27 beta 2-adrenoceptor polymorphism with lower airway reactivity in asthmatic subjects.
Lancet 1995;345(8959):1213-4.
1995: Ian P Hall; Michael I Kotlikoff
Use of cultured airway myocytes for study of airway smooth muscle.
The American journal of physiology 1995;268(1 Pt 1):L1-11.
1994: H Kume; Ian P Hall; Robert J Washabau; K Takagi; Michael I Kotlikoff
Beta-adrenergic agonists regulate KCa channels in airway smooth muscle by cAMP-dependent and -independent mechanisms.
The Journal of clinical investigation 1994;93(1):371-9.
1993: S Widdop; K Daykin; Ian P Hall
Expression of muscarinic M2 receptors in cultured human airway smooth muscle cells.
American journal of respiratory cell and molecular biology 1993;9(5):541-6.
1993: K Daykin; S Widdop; Ian P Hall
Control of histamine induced inositol phospholipid hydrolysis in cultured human tracheal smooth muscle cells.
European journal of pharmacology 1993;246(2):135-40.
1993: Ian P Hall; K Daykin; S Widdop
Beta 2-adrenoceptor desensitization in cultured human airway smooth muscle.
Clinical science (London, England : 1979) 1993;84(2):151-7.
1993: Ian P Hall
Isoenzyme selective phosphodiesterase inhibitors: potential clinical uses.
British journal of clinical pharmacology 1993;35(1):1-7.
1992: Ian P Hall; S Widdop; P Townsend; K Daykin
Control of cyclic AMP levels in primary cultures of human tracheal smooth muscle cells.
British journal of pharmacology 1992;107(2):422-8.
1992: Ian P Hall
Agonist-induced inositol phosphate responses in bovine airway submucosal glands.
The American journal of physiology 1992;262(3 Pt 1):L257-62.