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Christer Halldin

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Andrea Varrone; Torsten Zimmermann; Nabil Al-Tawil; Ronald Boellaard; Jacqueline Borg; Maria Eriksdotter; Anton Forsberg; Balázs Gulyás; Anja Hoffmann; Adriaan A Lammertsma; Patrik Mattsson; Sangram Nag; Marcus Schultze-Mosgau; Akihiro Takano; Andrea Thiele; Christer Halldin
In vivo imaging of the 18-kDa translocator protein (TSPO) with [(18)F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients.
Jan D Andersson; Lars Farde; Patrick Raboisson; Nicholas Seneca; Phong Truong; David Wensbo; Christer Halldin
Palladium mediated (11)C-cyanation and characterization in the non-human primate brain of the novel mGluR5 radioligand [(11)C]AZD9272.
Miklós Tóth; Andrea Varrone; Nika Adham; István Gyertyán; Christer Halldin; Attila Horváth; Béla Kiss; István Laszlovszky; Carsten Steiger; Balázs Gulyás
Brain uptake and distribution of the dopamine D3 /D2 receptor partial agonist [11 C]cariprazine: an in vivo positron emission tomography study in nonhuman primates.

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All Publications

2013: Andrea Varrone; Torsten Zimmermann; Nabil Al-Tawil; Ronald Boellaard; Jacqueline Borg; Maria Eriksdotter; Anton Forsberg; Balázs Gulyás; Anja Hoffmann; Adriaan A Lammertsma; Patrik Mattsson; Sangram Nag; Marcus Schultze-Mosgau; Akihiro Takano; Andrea Thiele; Christer Halldin
In vivo imaging of the 18-kDa translocator protein (TSPO) with [(18)F]FEDAA1106 and PET does not show increased binding in Alzheimer's disease patients.
European journal of nuclear medicine and molecular imaging 2013;40(6):921-31.
2013: Jan D Andersson; Lars Farde; Patrick Raboisson; Nicholas Seneca; Phong Truong; David Wensbo; Christer Halldin
Palladium mediated (11)C-cyanation and characterization in the non-human primate brain of the novel mGluR5 radioligand [(11)C]AZD9272.
Nuclear medicine and biology 2013;40(4):547-53.
2013: Miklós Tóth; Andrea Varrone; Nika Adham; István Gyertyán; Christer Halldin; Attila Horváth; Béla Kiss; István Laszlovszky; Carsten Steiger; Balázs Gulyás
Brain uptake and distribution of the dopamine D3 /D2 receptor partial agonist [11 C]cariprazine: an in vivo positron emission tomography study in nonhuman primates.
Synapse (New York, N.Y.) 2013;67(5):258-64.
2013: Joar Guterstam; Christer Halldin; Nitya Jayaram-Lindström; Simon Cervenka; Lars Farde; J James Frost; Johan Franck
Effects of amphetamine on the human brain opioid system--a positron emission tomography study.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2013;16(4):763-9.
2013: Magnus Schou; Katarina Varnäs; Balázs Gulyás; Christer Halldin; Aurelija Jucaite; Lars Farde
Radiolabeling of the cannabinoid receptor agonist AZD1940 with carbon-11 and PET microdosing in non-human primate.
Nuclear medicine and biology 2013;40(3):410-4.
2013: Anton Forsberg; Yvonne Freund-Levi; Christer Halldin; Fredrik Jeppsson; Peter Johnström; Per Julin; Anders Juréus; Johan Sandell; Magnus Schou; Jan Andersson; Zsolt Cselényi; Maria Eriksdotter; Lars Farde; Britt-Marie Swahn; Katarina Varnäs; Samuel Svensson
Low background and high contrast PET imaging of amyloid-β with [11C]AZD2995 and [11C]AZD2184 in Alzheimer's disease patients.
European journal of nuclear medicine and molecular imaging 2013;40(4):580-93.
2013: Yoko Ikoma; Akihiro Takano; Andrea Varrone; Christer Halldin
Graphic plot analysis for estimating binding potential of translocator protein (TSPO) in positron emission tomography studies with [¹⁸F]FEDAA1106.
NeuroImage 2013;69():78-86.
2013: Fumitoshi Kodaka; Kazuhiko Nakayama; Takeshi Sasaki; Lars Farde; Saori Fujie; Hironobu Fujiwara; Christer Halldin; Hiroshi Ito; Yasuyuki Kimura; Harumasa Takano; Tetsuya Suhara
Test-retest reproducibility of dopamine D2/3 receptor binding in human brain measured by PET with [11C]MNPA and [11C]raclopride.
European journal of nuclear medicine and molecular imaging 2013;40(4):574-9.
2013: Ryuji Nakao; Christer Halldin
"Mixed" anionic and non-ionic micellar liquid chromatography for high-speed radiometabolite analysis of positron emission tomography radioligands.
Journal of chromatography. A 2013;1281():54-9.
2013: Akihiro Takano; Christer Halldin; Lars Farde
SERT and NET occupancy by venlafaxine and milnacipran in nonhuman primates: a PET study.
Psychopharmacology 2013;226(1):147-53.
2013: Nahid Amini; Ryuji Nakao; Magnus Schou; Christer Halldin
Identification of PET radiometabolites by cytochrome P450, UHPLC/Q-ToF-MS and fast radio-LC: applied to the PET radioligands [11C]flumazenil, [18F]FE-PE2I, and [11C]PBR28.
Analytical and bioanalytical chemistry 2013;405(4):1303-10.
2013: Akihiro Takano; Nabil Al Tawil; Andrea Thiele; Andrea Varrone; Victor L Villemagne; Torsten Zimmermann; Balázs Gulyás; Jan Hillert; Anja Hoffmann; Thomas Kucinski; Richard Macdonell; Sangram Nag; Fredrik Piehl; Christopher C Rowe; Marcus Schultze-Mosgau; Per Stenkrona; Christer Halldin
In vivo TSPO imaging in patients with multiple sclerosis: a brain PET study with [18F]FEDAA1106.
EJNMMI research 2013;3(1):30.
2013: S Nag; A Thiele; Andrea Varrone; É Keller; B Gulyas; T Heinrich; Georg Kettschau; L Lehmann; Christer Halldin
Synthesis and biological evaluation of novel propargyl amines as potential fluorine-18 labeled radioligands for detection of MAO-B activity.
Bioorganic & medicinal chemistry 2013;21(1):186-95.
2012: Ryuji Nakao; Magnus Schou; Christer Halldin
Rapid metabolite analysis of positron emission tomography radioligands by direct plasma injection combining micellar cleanup with high submicellar liquid chromatography with radiometric detection.
Journal of chromatography. A 2012;1266():76-83.
2012: Damian Brockschnieder; Ludger M Dinkelborg; Jan Andersson; Ulf Boemer; Matthias Friebe; Balázs Gulyás; Christer Halldin; Tobias Heinrich; Sabine Krause; Heribert Schmitt-Willich; Miklos Toth; Andrea Varrone; Thomas Dyrks
Preclinical characterization of a novel class of 18F-labeled PET tracers for amyloid-β.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(11):1794-801.
2012: Balázs Gulyás; Anu Airaksinen; Jan Hillert; Kosta Kostulas; Per Lindström; Martin Schain; Miklós Tóth; Adám Vas; Christer Halldin
Evolution of microglial activation in ischaemic core and peri-infarct regions after stroke: a PET study with the TSPO molecular imaging biomarker [((11))C]vinpocetine.
Journal of the neurological sciences 2012;320(1-2):110-7.
2012: Johan Lundberg; Mikael Tiger; Christer Halldin; Mikael Landén; Lars Farde
Serotonin transporter occupancy with TCAs and SSRIs: a PET study in patients with major depressive disorder.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2012;15(8):1167-72.
2012: Takeshi Sasaki; Chie Seki; Masayuki Suzuki; Hidehiko Takahashi; Keisuke Takahata; Harumasa Takano; Andrea Varrone; Ryosuke Arakawa; Saori Fujie; Hironobu Fujiwara; Toshimitsu Fukumura; Christer Halldin; Hiroshi Ito; Yasuyuki Kimura; Fumitoshi Kodaka; Ryuji Nakao; Toru Nishikawa; Tsuyoshi Nogami; Tetsuya Suhara
Quantification of dopamine transporter in human brain using PET with 18F-FE-PE2I.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(7):1065-73.
2012: Ryuji Nakao; Magnus Schou; Christer Halldin
Rapid and sensitive measurement of PET radioligands in plasma by fast liquid chromatography/radiometric detection.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2012;895-896():116-22.
2012: S Nag; A Thiele; Andrea Varrone; B Gulyas; T Heinrich; Georg Kettschau; L Lehmann; Christer Halldin
Synthesis and evaluation of [¹⁸F]fluororasagiline, a novel positron emission tomography (PET) radioligand for monoamine oxidase B (MAO-B).
Bioorganic & medicinal chemistry 2012;20(9):3065-71.
2012: Ryuji Nakao; Magnus Schou; Christer Halldin
Direct plasma metabolite analysis of positron emission tomography radioligands by micellar liquid chromatography with radiometric detection.
Analytical chemistry 2012;84(7):3222-30.
2012: Sjoerd J Finnema; Christer Halldin; Tzung-Jeng Hwang; Andrea Varrone; Lars Farde
Confirmation of fenfluramine effect on 5-HT(1B) receptor binding of [(11)C]AZ10419369 using an equilibrium approach.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2012;32(4):685-95.
2012: Mahabuba Jahan; Raisa Krasikova; Andreas Muhs; Sangram Nag; Andrea Pfeifer; Christian Spenger; Urs Weber; Dieter Willbold; Balázs Gulyás; Christer Halldin
Fluorine-18 labeling of three novel D-peptides by conjugation with N-succinimidyl-4-[18F]fluorobenzoate and preliminary examination by postmortem whole-hemisphere human brain autoradiography.
Nuclear medicine and biology 2012;39(3):315-23.
2012: Sangram Nag; Andrea Thiele; Miklós Tóth; Andrea Varrone; Tobias Heinrich; Georg Kettschau; Lutz Lehmann; Christer Halldin
In vivo evaluation in cynomolgus monkey brain and metabolism of [¹⁸F]fluorodeprenyl: a new MAO-B pet radioligand.
Synapse (New York, N.Y.) 2012;66(4):323-30.
2012: Zsolt Cselényi; Anton Forsberg; Christer Halldin; Peter Johnström; Maria Eriksdotter Jönhagen; Per Julin; Magnus Schou; Samuel Svensson; Katarina Varnäs; Lars Farde
Clinical validation of 18F-AZD4694, an amyloid-β-specific PET radioligand.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2012;53(3):415-24.
2012: Martin Schain; Per Stenkrona; Miklós Tóth; Zsolt Cselényi; Lars Farde; Christer Halldin; Andrea Varrone
Quantification of serotonin transporter availability with [11C]MADAM--a comparison between the ECAT HRRT and HR systems.
NeuroImage 2012;60(1):800-7.
2012: Ikuo Odano; Ivanka Savic; Andrea Varrone; Carolina Ciumas; Christer Halldin; Aurelija Jucaite; Per Karlsson; Lars Farde
Quantitative PET analyses of regional [11C]PE2I binding to the dopamine transporter--application to juvenile myoclonic epilepsy.
NeuroImage 2012;59(4):3582-93.
2012: Andrea Varrone; Balázs Gulyás; Cathrine Jonsson; Michael G Stabin; Akihiro Takano; Christer Halldin
Simplified quantification and whole-body distribution of [18F]FE-PE2I in nonhuman primates: prediction for human studies.
Nuclear medicine and biology 2012;39(2):295-303.
2012: Takeshi Fuchigami; Balázs Gulyás; Jan D Andersson; Sjoerd J Finnema; Mamoru Haratake; Zhisheng Jia; Yasuhiro Magata; Ryuji Nakao; Morio Nakayama; Akihiro Takano; Christer Halldin
Synthesis and evaluation of 2-chloro N-[(S)-{(S)-1-[11 C]methylpiperidin-2-yl} (phenyl)methyl]3-trifluoromethyl-benzamide ([11 C]N-methyl-SSR504734) as a PET radioligand for glycine transporter 1.
EJNMMI research 2012;2(1):37.
2012: Balázs Gulyás; Zsuzsa Beliczai; Karoly Gulya; Mahabuba Jahan; Zhisheng Jia; Péter Kása; Andreas Muhs; Andrea Pfeifer; Christian Spenger; Urs Weber; Dieter Willbold; Christer Halldin
Distribution and binding of 18F-labeled and 125I-labeled analogues of ACI-80, a prospective molecular imaging biomarker of disease: a whole hemisphere post mortem autoradiography study in human brains obtained from Alzheimer's disease patients.
Neurochemistry international 2012;60(2):153-62.
2012: B Gulyas; Jan Hillert; Kosta Kostulas; Evgeny Shchukin; Miklos Toth; Adám Vas; Christer Halldin
Visualising neuroinflammation in post-stroke patients: a comparative PET study with the TSPO molecular imaging biomarkers [11C]PK11195 and [11C]vinpocetine.
Current radiopharmaceuticals 2012;5(1):19-28.
2011: Nicholas Seneca; Sándor Farkas; Sjoerd J Finnema; István Gyertyán; Christer Halldin; Attila Horváth; Robert B Innis; Margó Kapás; Béla Kiss; István Laszlovszky; Gabriella Pásztor; Balázs Gulyás
Occupancy of dopamine D₂ and D₃ and serotonin 5-HT₁A receptors by the novel antipsychotic drug candidate, cariprazine (RGH-188), in monkey brain measured using positron emission tomography.
Psychopharmacology 2011;218(3):579-87.
2011: Akihiro Takano; Andrea Thiele; Andrea Varrone; Torsten Zimmermann; Anja Hoffmann; Cathrine Jonsson; Per Karlsson; Stig Larsson; Richard Odh; Nils Sjoholm; Richard Sparks; Nabil Al Tawil; Balázs Gulyás; Christer Halldin
Biodistribution and radiation dosimetry of the 18 kDa translocator protein (TSPO) radioligand [18F]FEDAA1106: a human whole-body PET study.
European journal of nuclear medicine and molecular imaging 2011;38(11):2058-65.
2011: Magdalena Nord; Svante Nyberg; Jacob Brogren; Christer Halldin; Aurelija Jucaite; Lars Farde
Comparison of D₂ dopamine receptor occupancy after oral administration of quetiapine fumarate immediate-release and extended-release formulations in healthy subjects.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2011;14(10):1357-66.
2011: Andrea Varrone; Johnny Vercouillie; Jean Bernard Deloye; Patrick Emond; Denis Guilloteau; Balázs Gulyás; Cathrine Jonsson; Ryuji Nakao; Michael G Stabin; Vladimir Stepanov; Miklós Tóth; Christer Halldin
Imaging of the striatal and extrastriatal dopamine transporter with (18)F-LBT-999: quantification, biodistribution, and radiation dosimetry in nonhuman primates.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(8):1313-21.
2011: Akihiro Takano; Balázs Gulyás; Christer Halldin; Sangram Nag; Lars Farde
NET occupancy by clomipramine and its active metabolite, desmethylclomipramine, in non-human primates in vivo.
Psychopharmacology 2011;216(2):279-86.
2011: Balázs Gulyás; Adám Vas; Miklós Tóth; Akihiro Takano; Andrea Varrone; Zsolt Cselényi; Martin Schain; Patrik Mattsson; Christer Halldin
Age and disease related changes in the translocator protein (TSPO) system in the human brain: positron emission tomography measurements with [11C]vinpocetine.
NeuroImage 2011;56(3):1111-21.
2011: Sean R Donohue; Robert F Dannals; Christer Halldin; Victor W Pike
N-(4-cyanotetrahydro-2H-pyran-4-yl) and N-(1-cyanocyclohexyl) derivatives of 1,5-diarylpyrazole-3-carboxamides showing high affinity for 18 kDa translocator protein and/or cannabinoid receptors.
Journal of medicinal chemistry 2011;54(8):2961-70.
2011: Pavitra Kannan; Kyle R Brimacombe; William C Kreisl; Jeih-San Liow; Sami S Zoghbi; Sanjay Telu; Yi Zhang; Victor W Pike; Christer Halldin; Michael M Gottesman; Robert B Innis; Matthew D Hall
Lysosomal trapping of a radiolabeled substrate of P-glycoprotein as a mechanism for signal amplification in PET.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(6):2593-8.
2011: Jan D Andersson; M Edward Pierson; Sjoerd J Finnema; Balázs Gulyás; Richard Heys; Charles S Elmore; Lars Farde; Christer Halldin
Development of a PET radioligand for the central 5-HT1B receptor: radiosynthesis and characterization in cynomolgus monkeys of eight radiolabeled compounds.
Nuclear medicine and biology 2011;38(2):261-72.
2011: Katarina Varnäs; Svante Nyberg; Per Karlsson; M Edward Pierson; Matts Kågedal; Zsolt Cselényi; Dennis McCarthy; Alan Xiao; Minli Zhang; Christer Halldin; Lars Farde
Dose-dependent binding of AZD3783 to brain 5-HT1B receptors in non-human primates and human subjects: a positron emission tomography study with [11C]AZ10419369.
Psychopharmacology 2011;213(2-3):533-45.
2011: Fumitoshi Kodaka; Hiroshi Ito; Harumasa Takano; Hidehiko Takahashi; Ryosuke Arakawa; Michie Miyoshi; Masaki Okumura; Tatsui Otsuka; Kazuhiko Nakayama; Christer Halldin; Lars Farde; Tetsuya Suhara
Effect of risperidone on high-affinity state of dopamine D2 receptors: a PET study with agonist ligand [11C](R)-2-CH3O-N-n-propylnorapomorphine.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2011;14(1):83-9.
2011: Mahabuba Jahan; Lars Johansson; Peter Johnström; Olle Korsgren; Anders Sundin; Olof Eriksson; Christer Halldin
Decreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PET.
EJNMMI research 2011;1(1):33.
2011: Andrea Varrone; Miklós Tóth; Carsten Steiger; Akihiro Takano; Denis Guilloteau; Masanori Ichise; Balázs Gulyás; Christer Halldin
Kinetic analysis and quantification of the dopamine transporter in the nonhuman primate brain with 11C-PE2I and 18F-FE-PE2I.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2011;52(1):132-9.
2011: Balázs Gulyás; Elena Pavlova; Péter Kása; Karoly Gulya; Lidia Bakota; Szilvia Várszegi; Eva Keller; Mónika Csilla Horváth; Sangram Nag; István Hermecz; Kálmán Magyar; Christer Halldin
Activated MAO-B in the brain of Alzheimer patients, demonstrated by [11C]-L-deprenyl using whole hemisphere autoradiography.
Neurochemistry international 2011;58(1):60-8.
2011: Katarina Varnäs; Svante Nyberg; Christer Halldin; Andrea Varrone; Akihiro Takano; Per Karlsson; Jan Andersson; Dennis McCarthy; Mark Smith; M Edward Pierson; Johan Söderström; Lars Farde
Quantitative analysis of [11C]AZ10419369 binding to 5-HT1B receptors in human brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2011;31(1):113-23.
2010: Jan D Andersson; Katarina Varnäs; Zsolt Cselényi; Balázs Gulyás; David Wensbo; Sjoerd J Finnema; Britt-Marie Swahn; Samuel Svensson; Svante Nyberg; Lars Farde; Christer Halldin
Radiosynthesis of the candidate beta-amyloid radioligand [(11)C]AZD2184: Positron emission tomography examination and metabolite analysis in cynomolgus monkeys.
Synapse (New York, N.Y.) 2010;64(10):733-41.
2010: Andrea Varrone; Christer Halldin
Molecular imaging of the dopamine transporter.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(9):1331-4.
2010: Mette Skinbjerg; Nicholas Seneca; Jeih-San Liow; Jinsoo Hong; David Weinshenker; Victor W Pike; Christer Halldin; David R Sibley; Robert B Innis
Dopamine beta-hydroxylase-deficient mice have normal densities of D(2) dopamine receptors in the high-affinity state based on in vivo PET imaging and in vitro radioligand binding.
Synapse (New York, N.Y.) 2010;64(9):699-703.
2010: Garth E Terry; Jussi Hirvonen; Jeih-San Liow; Nicholas Seneca; Johannes T Tauscher; John M Schaus; Lee A Phebus; Christian C Felder; Cheryl L Morse; Victor W Pike; Christer Halldin; Robert B Innis
Biodistribution and dosimetry in humans of two inverse agonists to image cannabinoid CB1 receptors using positron emission tomography.
European journal of nuclear medicine and molecular imaging 2010;37(8):1499-506.
2010: S J Finnema; Andrea Varrone; T J Hwang; Balázs Gulyás; M E Pierson; Christer Halldin; Lars Farde
Fenfluramine-induced serotonin release decreases [11C]AZ10419369 binding to 5-HT1B-receptors in the primate brain.
Synapse (New York, N.Y.) 2010;64(7):573-7.
2010: Mizuho Sekine; Ryosuke Arakawa; Hiroshi Ito; Masaki Okumura; Takeshi Sasaki; Hidehiko Takahashi; Harumasa Takano; Yoshiro Okubo; Christer Halldin; Tetsuya Suhara
Norepinephrine transporter occupancy by antidepressant in human brain using positron emission tomography with (S,S)-[18F]FMeNER-D2.
Psychopharmacology 2010;210(3):331-6.
2010: Pavitra Kannan; Kyle R Brimacombe; Sami S Zoghbi; Jeih-San Liow; Cheryl Morse; Andrew K Taku; Victor W Pike; Christer Halldin; Robert B Innis; Michael M Gottesman; Matthew D Hall
N-desmethyl-loperamide is selective for P-glycoprotein among three ATP-binding cassette transporters at the blood-brain barrier.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(6):917-22.
2010: Simon Cervenka; Andrea Varrone; Erik Fransén; Christer Halldin; Lars Farde
PET studies of D2-receptor binding in striatal and extrastriatal brain regions: Biochemical support in vivo for separate dopaminergic systems in humans.
Synapse (New York, N.Y.) 2010;64(6):478-85.
2010: Balázs Gulyás; Damian Brockschnieder; Sangram Nag; Elena Pavlova; Péter Kása; Zsuzsa Beliczai; Adám Légrádi; Karoly Gulya; Andrea Thiele; Thomas Dyrks; Christer Halldin
The norepinephrine transporter (NET) radioligand (S,S)-[18F]FMeNER-D2 shows significant decreases in NET density in the human brain in Alzheimer's disease: a post-mortem autoradiographic study.
Neurochemistry international 2010;56(6-7):789-98.
2010: Mette Skinbjerg; Jeih-San Liow; Nicholas Seneca; Jinsoo Hong; Shuiyu Lu; Annika Thorsell; Markus Heilig; Victor W Pike; Christer Halldin; David R Sibley; Robert B Innis
D2 dopamine receptor internalization prolongs the decrease of radioligand binding after amphetamine: a PET study in a receptor internalization-deficient mouse model.
NeuroImage 2010;50(4):1402-7.
2010: Aurelija Jucaite; Hans Forssberg; Per Karlsson; Christer Halldin; Lars Farde
Age-related reduction in dopamine D1 receptors in the human brain: from late childhood to adulthood, a positron emission tomography study.
Neuroscience 2010;167(1):104-10.
2010: Simon Cervenka; J Petter Gustavsson; Christer Halldin; Lars Farde
Association between striatal and extrastriatal dopamine D2-receptor binding and social desirability.
NeuroImage 2010;50(1):323-8.
2010: Sjoerd J Finnema; Benny Bang-Andersen; Håkan V Wikström; Christer Halldin
Current state of agonist radioligands for imaging of brain dopamine D2/D3 receptors in vivo with positron emission tomography.
Current topics in medicinal chemistry 2010;10(15):1477-98.
2010: Garth E Terry; Jussi Hirvonen; Jeih-San Liow; Sami S Zoghbi; Robert L Gladding; Johannes T Tauscher; John M Schaus; Lee A Phebus; Christian Felder; Cheryl L Morse; Sean R Donohue; Victor W Pike; Christer Halldin; Robert B Innis
Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2010;51(1):112-20.
2009: Sean R Donohue; Katarina Varnäs; Zhisheng Jia; Balázs Gulyás; Victor W Pike; Christer Halldin
Synthesis and in vitro autoradiographic evaluation of a novel high-affinity radioiodinated ligand for imaging brain cannabinoid subtype-1 receptors.
Bioorganic & medicinal chemistry letters 2009;19(21):6209-12.
2009: Garth E Terry; Jeih-San Liow; Sami S Zoghbi; Jussi Hirvonen; Amanda G Farris; Alicja Lerner; Johannes T Tauscher; John M Schaus; Lee A Phebus; Christian Felder; Cheryl L Morse; Jinsoo S Hong; Victor W Pike; Christer Halldin; Robert B Innis
Quantitation of cannabinoid CB1 receptors in healthy human brain using positron emission tomography and an inverse agonist radioligand.
NeuroImage 2009;48(2):362-70.
2009: Akihiro Takano; Balázs Gulyás; Andrea Varrone; Christer Halldin
Comparative evaluations of norepinephrine transporter radioligands with reference tissue models in rhesus monkeys: (S,S)-[18F]FMeNER-D2 and (S,S)-[11C]MeNER.
European journal of nuclear medicine and molecular imaging 2009;36(11):1885-91.
2009: Sari Karlsson; Lars Nyberg; Per Karlsson; Håkan Fischer; Petra Thilers; Stuart Macdonald; Yvonne Brehmer; Anna Rieckmann; Christer Halldin; Lars Farde; Lars Bäckman
Modulation of striatal dopamine D1 binding by cognitive processing.
NeuroImage 2009;48(2):398-404.
2009: Svante Nyberg; Maria Eriksdotter Jönhagen; Zsolt Cselényi; Christer Halldin; Per Julin; Hans Olsson; Yvonne Freund-Levi; Jan Andersson; Katarina Varnäs; Samuel Svensson; Lars Farde
Detection of amyloid in Alzheimer's disease with positron emission tomography using [11C]AZD2184.
European journal of nuclear medicine and molecular imaging 2009;36(11):1859-63.
2009: P Kannan; C John; Sami S Zoghbi; Christer Halldin; Michael M Gottesman; Robert B Innis; M D Hall
Imaging the function of P-glycoprotein with radiotracers: pharmacokinetics and in vivo applications.
Clinical pharmacology and therapeutics 2009;86(4):368-77.
2009: Andrea Varrone; Carsten Steiger; Magnus Schou; Akihiro Takano; Sjoerd J Finnema; Denis Guilloteau; Balázs Gulyás; Christer Halldin
In vitro autoradiography and in vivo evaluation in cynomolgus monkey of [18F]FE-PE2I, a new dopamine transporter PET radioligand.
Synapse (New York, N.Y.) 2009;63(10):871-80.
2009: Andrea Varrone; Nils Sjöholm; Lars Eriksson; Balázs Gulyás; Christer Halldin; Lars Farde
Advancement in PET quantification using 3D-OP-OSEM point spread function reconstruction with the HRRT.
European journal of nuclear medicine and molecular imaging 2009;36(10):1639-50.
2009: Magnus Schou; Carsten Steiger; Andrea Varrone; Denis Guilloteau; Christer Halldin
Synthesis, radiolabeling and preliminary in vivo evaluation of [18F]FE-PE2I, a new probe for the dopamine transporter.
Bioorganic & medicinal chemistry letters 2009;19(16):4843-5.
2009: Akihiro Takano; Balázs Gulyás; Andrea Varrone; Ralph Paul Maguire; Christer Halldin
Saturated norepinephrine transporter occupancy by atomoxetine relevant to clinical doses: a rhesus monkey study with (S,S)-[(18)F]FMeNER-D (2).
European journal of nuclear medicine and molecular imaging 2009;36(8):1308-14.
2009: Viktorija Trajkovska; Lisbeth Kirkegaard; Gesa Krey; Anders B Marcussen; Morten S Thomsen; Sabine Chourbaji; Christiane Brandwein; Stephanie Ridder; Christer Halldin; Peter Gass; Gitte Moos Knudsen; Susana Aznar
Activation of glucocorticoid receptors increases 5-HT2A receptor levels.
Experimental neurology 2009;218(1):83-91.
2009: Mette Skinbjerg; Marjorie A Ariano; Annika Thorsell; Markus Heilig; Christer Halldin; Robert B Innis; David R Sibley
Arrestin3 mediates D(2) dopamine receptor internalization.
Synapse (New York, N.Y.) 2009;63(7):621-4.
2009: Jacqueline Borg; Susanne Henningsson; Tomoyuki Saijo; Makoto Inoue; Jessica Bah; Lars Westberg; Johan Lundberg; Hristina Jovanovic; Bengt Andrée; Anna-Lena Nordstrom; Christer Halldin; Elias Eriksson; Lars Farde
Serotonin transporter genotype is associated with cognitive performance but not regional 5-HT1A receptor binding in humans.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2009;12(6):783-92.
2009: Mette Skinbjerg; Yoon Namkung; Christer Halldin; Robert B Innis; David R Sibley
Pharmacological characterization of 2-methoxy-N-propylnorapomorphine's interactions with D2 and D3 dopamine receptors.
Synapse (New York, N.Y.) 2009;63(6):462-75.
2009: Tatsui Otsuka; Hiroshi Ito; Christer Halldin; Hidehiko Takahashi; Harumasa Takano; Ryosuke Arakawa; Masaki Okumura; Fumitoshi Kodaka; Michie Miyoshi; Mizuho Sekine; Chie Seki; Ryuji Nakao; Kazutoshi Suzuki; Sjoerd Finnema; Yoshio Hirayasu; Tetsuya Suhara; Lars Farde
Quantitative PET analysis of the dopamine D2 receptor agonist radioligand 11C-(R)-2-CH3O-N-n-propylnorapomorphine in the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2009;50(5):703-10.
2009: Sjoerd J Finnema; Christer Halldin; Benny Bang-Andersen; Balázs Gulyás; Christoffer Bundgaard; Håkan V Wikström; Lars Farde
Dopamine D(2/3) receptor occupancy of apomorphine in the nonhuman primate brain--a comparative PET study with [11C]raclopride and [11C]MNPA.
Synapse (New York, N.Y.) 2009;63(5):378-89.
2009: Hristina Jovanovic; Per Karlsson; Asta Cerin; Christer Halldin; Anna-Lena Nordström
5-HT(1A) receptor and 5-HTT binding during the menstrual cycle in healthy women examined with [(11)C] WAY100635 and [(11)C] MADAM PET.
Psychiatry research 2009;172(1):31-7.
2009: Ikuo Odano; Christer Halldin; Per Karlsson; Andrea Varrone; Anu J Airaksinen; Raisa N Krasikova; Lars Farde
[18F]flumazenil binding to central benzodiazepine receptor studies by PET--quantitative analysis and comparisons with [11C]flumazenil.
NeuroImage 2009;45(3):891-902.
2009: Masaki Tokunaga; Nicholas Seneca; Ryong-Moon Shin; Jun Maeda; Shigeru Obayashi; Takashi Okauchi; Yuji Nagai; Ming-Rong Zhang; Ryuji Nakao; Hiroshi Ito; Robert B Innis; Christer Halldin; Kazutoshi Suzuki; Makoto Higuchi; Tetsuya Suhara
Neuroimaging and physiological evidence for involvement of glutamatergic transmission in regulation of the striatal dopaminergic system.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(6):1887-96.
2009: Jan Andersson; Phong Truong; Christer Halldin
In-target produced [11C]methane: Increased specific radioactivity.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2009;67(1):106-10.
2009: Balázs Gulyás; Boglárka Makkai; Péter Kása; Karoly Gulya; Lidia Bakota; Szilvia Várszegi; Zsuzsa Beliczai; Jan Andersson; László Csiba; Andrea Thiele; Thomas Dyrks; Tetsua Suhara; Kazutoshi Suzuki; Makato Higuchi; Christer Halldin
A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system.
Neurochemistry international 2009;54(1):28-36.
2009: Sjoerd J Finnema; Sean R Donohue; Sami S Zoghbi; Amira K Brown; Balázs Gulyás; Robert B Innis; Christer Halldin; Victor W Pike
Evaluation of [11C]PipISB and [18F]PipISB in monkey as candidate radioligands for imaging brain cannabinoid type-1 receptors in vivo.
Synapse (New York, N.Y.) 2009;63(1):22-30.
2009: Magnus Schou; Sami S Zoghbi; H Umesha Shetty; Evgeny Shchukin; Jeih-San Liow; Jinsoo Hong; Bengt A Andrée; Balázs Gulyás; Lars Farde; Robert B Innis; Victor W Pike; Christer Halldin
Investigation of the metabolites of (S,S)-[(11)C]MeNER in humans, monkeys and rats.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2009;11(1):23-30.
2009: Raisa N Krasikova; Jan Andersson; Phong Truong; Sangram Nag; Evgeny V Shchukin; Christer Halldin
A fully automated one-pot synthesis of [carbonyl-11C]WAY-100635 for clinical PET applications.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2009;67(1):73-8.
2008: Zsuzsa Beliczai; Szilvia Varszegi; Balazs Gulyas; Christer Halldin; Péter Kása; Karoly Gulya
Immunohistoblot analysis on whole human hemispheres from normal and Alzheimer diseased brains.
Neurochemistry international 2008;53(6-8):181-3.
2008: Alfons Verbruggen; Heinz H Coenen; Jean-Robert Deverre; Denis Guilloteau; Bengt Langstrom; Piero A Salvadori; Christer Halldin
Guideline to regulations for radiopharmaceuticals in early phase clinical trials in the EU.
European journal of nuclear medicine and molecular imaging 2008;35(11):2144-51.
2008: Nicholas Seneca; Sami S Zoghbi; Mette Skinbjerg; Jeih-San Liow; Jinsoo Hong; David R Sibley; Victor W Pike; Christer Halldin; Robert B Innis
Occupancy of dopamine D2/3 receptors in rat brain by endogenous dopamine measured with the agonist positron emission tomography radioligand [11C]MNPA.
Synapse (New York, N.Y.) 2008;62(10):756-63.
2008: Sean R Donohue; Joseph H Krushinski; Victor W Pike; Eyassu Chernet; Lee A Phebus; Amy K Chesterfield; Christian Felder; Christer Halldin; John M Schaus
Synthesis, ex vivo evaluation, and radiolabeling of potent 1,5-diphenylpyrrolidin-2-one cannabinoid subtype-1 receptor ligands as candidates for in vivo imaging.
Journal of medicinal chemistry 2008;51(18):5833-42.
2008: Sean R Donohue; Victor W Pike; Sjoerd J Finnema; Phong Truong; Jan Andersson; Balázs Gulyás; Christer Halldin
Discovery and labeling of high-affinity 3,4-diarylpyrazolines as candidate radioligands for in vivo imaging of cannabinoid subtype-1 (CB1) receptors.
Journal of medicinal chemistry 2008;51(18):5608-16.
2008: C Ciumas; T-B Robins Wahlin; A Jucaite; P Lindstrom; Christer Halldin; I Savic
Reduced dopamine transporter binding in patients with juvenile myoclonic epilepsy.
Neurology 2008;71(11):788-94.
2008: Nicholas Seneca; Mette Skinbjerg; Sami S Zoghbi; Jeih-San Liow; Robert L Gladding; Jinsoo Hong; Pavitra Kannan; Edward Tuan; David R Sibley; Christer Halldin; Victor W Pike; Robert B Innis
Kinetic brain analysis and whole-body imaging in monkey of [11C]MNPA: a dopamine agonist radioligand.
Synapse (New York, N.Y.) 2008;62(9):700-9.
2008: Akihiro Takano; Andrea Varrone; Balázs Gulyás; Per Karlsson; Johannes Tauscher; Christer Halldin
Mapping of the norepinephrine transporter in the human brain using PET with (S,S)-[18F]FMeNER-D2.
NeuroImage 2008;42(2):474-82.
2008: John Paoli; Christer Halldin; Marica B Ericson; Ann-Marie Wennberg
Nerve blocks provide effective pain relief during topical photodynamic therapy for extensive facial actinic keratoses.
Clinical and experimental dermatology 2008;33(5):559-64.
2008: Ryosuke Arakawa; Masaki Okumura; Hiroshi Ito; Chie Seki; Hidehiko Takahashi; Harumasa Takano; Ryuji Nakao; Kazutoshi Suzuki; Yoshiro Okubo; Christer Halldin; Tetsuya Suhara
Quantitative analysis of norepinephrine transporter in the human brain using PET with (S,S)-18F-FMeNER-D2.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2008;49(8):1270-6.
2008: Simon Cervenka; Christer Halldin; Lars Farde
Age-related diurnal effect on D2 receptor binding: a preliminary PET study.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2008;11(5):671-8.
2008: Anu J Airaksinen; Sangram Nag; Sjoerd J Finnema; Jogeshwar Mukherjee; Sankha Chattopadhyay; Balázs Gulyás; Lars Farde; Christer Halldin
[11C]cyclopropyl-FLB 457: a PET radioligand for low densities of dopamine D2 receptors.
Bioorganic & medicinal chemistry 2008;16(13):6467-73.
2008: Garth Terry; Jeih-San Liow; Eyassu Chernet; Sami S Zoghbi; Lee A Phebus; Christian Felder; Johannes Tauscher; John M Schaus; Victor W Pike; Christer Halldin; Robert B Innis
Positron emission tomography imaging using an inverse agonist radioligand to assess cannabinoid CB1 receptors in rodents.
NeuroImage 2008;41(3):690-8.
2008: M Edward Pierson; Jan Andersson; Svante Nyberg; Dennis J McCarthy; Sjoerd J Finnema; Katarina Varnäs; Akihiro Takano; Per Karlsson; Balázs Gulyás; Amy M Medd; Chi-Ming Lee; Mark E Powell; J Richard Heys; William Potts; Nicholas Seneca; Ladislav Mrzljak; Lars Farde; Christer Halldin
[11C]AZ10419369: a selective 5-HT1B receptor radioligand suitable for positron emission tomography (PET). Characterization in the primate brain.
NeuroImage 2008;41(3):1075-85.
2008: Jussi Hirvonen; Jarkko Johansson; Mika Teräs; Vesa Oikonen; Ville Lumme; Pauliina Virsu; Anne Roivainen; Kjell Någren; Christer Halldin; Lars Farde; Jarmo Hietala
Measurement of striatal and extrastriatal dopamine transporter binding with high-resolution PET and [11C]PE2I: quantitative modeling and test-retest reproducibility.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2008;28(5):1059-69.
2008: Simon Cervenka; Lars Bäckman; Zsolt Cselényi; Christer Halldin; Lars Farde
Associations between dopamine D2-receptor binding and cognitive performance indicate functional compartmentalization of the human striatum.
NeuroImage 2008;40(3):1287-95.
2008: Akihiro Takano; Christer Halldin; Andrea Varrone; Per Karlsson; Nils Sjöholm; James B Stubbs; Magnus Schou; Anu J Airaksinen; Johannes Tauscher; Balázs Gulyás
Biodistribution and radiation dosimetry of the norepinephrine transporter radioligand (S,S)-[18F]FMeNER-D2: a human whole-body PET study.
European journal of nuclear medicine and molecular imaging 2008;35(3):630-6.
2008: Anna-Lena Nordstrom; Mattias Mansson; Hristina Jovanovic; Per Karlsson; Christer Halldin; Lars Farde; Kimberly E Vanover; Uli Hacksell; Mark R Brann; Robert E Davis; David M Weiner
PET analysis of the 5-HT2A receptor inverse agonist ACP-103 in human brain.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2008;11(2):163-71.
2008: Hristina Jovanovic; Johan Lundberg; Per Karlsson; Asta Cerin; Tomoyuki Saijo; Andrea Varrone; Christer Halldin; Anna-Lena Nordström
Sex differences in the serotonin 1A receptor and serotonin transporter binding in the human brain measured by PET.
NeuroImage 2008;39(3):1408-19.
2008: Adám Vas; Yevgeni Shchukin; Virginija D Karrenbauer; Zsolt Cselényi; Kosta Kostulas; Jan Hillert; Ivanka Savic; Akihiro Takano; Christer Halldin; Balázs Gulyás
Functional neuroimaging in multiple sclerosis with radiolabelled glia markers: preliminary comparative PET studies with [11C]vinpocetine and [11C]PK11195 in patients.
Journal of the neurological sciences 2008;264(1-2):9-17.
2008: Akihiro Takano; Balázs Gulyás; Andrea Varrone; Per Karlsson; Magnus Schou; Anu J Airaksinen; Francois Vandenhende; Johannes Tauscher; Christer Halldin
Imaging the norepinephrine transporter with positron emission tomography: initial human studies with (S,S)-[18F]FMeNER-D2.
European journal of nuclear medicine and molecular imaging 2008;35(1):153-7.
2008: Fumihiko Yasuno; Amira K Brown; Sami S Zoghbi; Joseph H Krushinski; Eyassu Chernet; Johannes Tauscher; John M Schaus; Lee A Phebus; Amy K Chesterfield; Christian Felder; Robert L Gladding; Jinsoo Hong; Christer Halldin; Victor W Pike; Robert B Innis
The PET radioligand [11C]MePPEP binds reversibly and with high specific signal to cannabinoid CB1 receptors in nonhuman primate brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2008;33(2):259-69.
2007: Johan Lundberg; Jacqueline Borg; Christer Halldin; Lars Farde
A PET study on regional coexpression of 5-HT1A receptors and 5-HTT in the human brain.
Psychopharmacology 2007;195(3):425-33.
2007: Johan Lundberg; Jacob Strøyer Christophersen; Kamilla Buchberg Petersen; Henrik Loft; Christer Halldin; Lars Farde
PET measurement of serotonin transporter occupancy: a comparison of escitalopram and citalopram.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2007;10(6):777-85.
2007: Julie A McCarron; Sami S Zoghbi; H Umesha Shetty; Eric S Vermeulen; Håkan V Wikström; Masanori Ichise; Fumihiko Yasuno; Christer Halldin; Robert B Innis; Victor W Pike
Synthesis and initial evaluation of [11C](R)-RWAY in monkey-a new, simply labeled antagonist radioligand for imaging brain 5-HT1A receptors with PET.
European journal of nuclear medicine and molecular imaging 2007;34(10):1670-82.
2007: H Umesha Shetty; Sami S Zoghbi; Jeih-San Liow; Masanori Ichise; Jinsoo Hong; John L Musachio; Christer Halldin; Jurgen Seidel; Robert B Innis; Victor W Pike
Identification and regional distribution in rat brain of radiometabolites of the dopamine transporter PET radioligand [11C]PE2I.
European journal of nuclear medicine and molecular imaging 2007;34(5):667-78.
2007: Stepanov Vladimir; Magnus Schou; Jaak Järv; Christer Halldin
Synthesis of 3H-labeled N-(3-iodoprop-2E-enyl)-2beta-carbomethoxy-3beta-(4-methylphenyl)nortropane (PE2I) and its interaction with mice striatal membrane fragments.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 2007;65(3):293-300.
2007: Ming-Rong Zhang; Katsushi Kumata; Jun Maeda; Terushi Haradahira; Junko Noguchi; Tetsuya Suhara; Christer Halldin; Kazutoshi Suzuki
N-(5-Fluoro-2-phenoxyphenyl)-N-(2-[(131)I]iodo-5-me thoxybenzyl)acetamide: a potent iodinated radioligand for the peripheral-type benzodiazepine receptor in brain.
Journal of medicinal chemistry 2007;50(4):848-55.
2007: Magnus Schou; Victor W Pike; Judit Sóvágó; Balázs Gulyás; Peter T Gallagher; David Dobson; Magnus W Walter; Helene Rudyk; Lars Farde; Christer Halldin
Synthesis of 11C-labelled (R)-OHDMI and CFMME and their evaluation as candidate radioligands for imaging central norepinephrine transporters with PET.
Bioorganic & medicinal chemistry 2007;15(2):616-25.
2007: Magnus Schou; Victor W Pike; Christer Halldin
Development of radioligands for imaging of brain norepinephrine transporters in vivo with positron emission tomography.
Current topics in medicinal chemistry 2007;7(18):1806-16.
2007: Wadad Saba; Héric Valette; Marie-Anne Schöllhorn-Peyronneau; Christine Coulon; Michèle Ottaviani; Sylvie Chalon; Frederic Dolle; Patrick Emond; Christer Halldin; Julie Helfenbein; Jean-Claude Madelmont; Jean-Bernard Deloye; Denis Guilloteau; Michel Bottlaender
[11C]LBT-999: a suitable radioligand for investigation of extra-striatal dopamine transporter with PET.
Synapse (New York, N.Y.) 2007;61(1):17-23.
2006: Mirjam Talvik; Anna-Lena Nordström; Yoshiro Okubo; Hans Olsson; Jacqueline Borg; Christer Halldin; Lars Farde
Dopamine D2 receptor binding in drug-naïve patients with schizophrenia examined with raclopride-C11 and positron emission tomography.
Psychiatry research 2006;148(2-3):165-73.
2006: Hristina Jovanovic; Asta Cerin; Per Karlsson; Johan Lundberg; Christer Halldin; Anna-Lena Nordström
A PET study of 5-HT1A receptors at different phases of the menstrual cycle in women with premenstrual dysphoria.
Psychiatry research 2006;148(2-3):185-93.
2006: Thierry Vander Borght; S Asenbaum; P Bartenstein; Christer Halldin; O Kapucu; K Van Laere; A Varrone; K Tatsch
EANM procedure guidelines for brain tumour imaging using labelled amino acid analogues.
European journal of nuclear medicine and molecular imaging 2006;33(11):1374-80.
2006: Zsolt Cselényi; Hans Olsson; Christer Halldin; Balázs Gulyás; Lars Farde
A comparison of recent parametric neuroreceptor mapping approaches based on measurements with the high affinity PET radioligands [11C]FLB 457 and [11C]WAY 100635.
NeuroImage 2006;32(4):1690-708.
2006: Nicholas Seneca; Balázs Gulyás; Andrea Varrone; Magnus Schou; Anu Airaksinen; Johannes Tauscher; Francois Vandenhende; William Kielbasa; Lars Farde; Robert B Innis; Christer Halldin
Atomoxetine occupies the norepinephrine transporter in a dose-dependent fashion: a PET study in nonhuman primate brain using (S,S)-[18F]FMeNER-D2.
Psychopharmacology 2006;188(1):119-27.
2006: Johan Lundberg; Christer Halldin; Lars Farde
Measurement of serotonin transporter binding with PET and [11C]MADAM: a test-retest reproducibility study.
Synapse (New York, N.Y.) 2006;60(3):256-63.
2006: Simon Cervenka; Sven E Pålhagen; Robert A Comley; Georgios Panagiotidis; Zsolt Cselényi; Julian C Matthews; Robert Y Lai; Christer Halldin; Lars Farde
Support for dopaminergic hypoactivity in restless legs syndrome: a PET study on D2-receptor binding.
Brain : a journal of neurology 2006;129(Pt 8):2017-28.
2006: John L Musachio; Jinsoo Hong; Masanori Ichise; Nicholas Seneca; Amira K Brown; Jeih-San Liow; Christer Halldin; Robert B Innis; Victor W Pike; Rong He; Jia Zhou; Alan P Kozikowski
Development of new brain imaging agents based upon nocaine-modafinil hybrid monoamine transporter inhibitors.
Bioorganic & medicinal chemistry letters 2006;16(12):3101-4.
2006: Aurelija Jucaite; Ikuo Odano; Hans Olsson; Stefan Pauli; Christer Halldin; Lars Farde
Quantitative analyses of regional [11C]PE2I binding to the dopamine transporter in the human brain: a PET study.
European journal of nuclear medicine and molecular imaging 2006;33(6):657-68.
2006: Sean R Donohue; Christer Halldin; Victor W Pike
Synthesis and structure-activity relationships (SARs) of 1,5-diarylpyrazole cannabinoid type-1 (CB(1)) receptor ligands for potential use in molecular imaging.
Bioorganic & medicinal chemistry 2006;14(11):3712-20.
2006: Jacqueline Borg; Bengt Andrée; Johan Lundberg; Christer Halldin; Lars Farde
Search for correlations between serotonin 5-HT1A receptor expression and cognitive functions--a strategy in translational psychopharmacology.
Psychopharmacology 2006;185(3):389-94.
2006: Nicholas Seneca; Sjoerd J Finnema; Lars Farde; Balázs Gulyás; Håkan V Wikström; Christer Halldin; Robert B Innis
Effect of amphetamine on dopamine D2 receptor binding in nonhuman primate brain: a comparison of the agonist radioligand [11C]MNPA and antagonist [11C]raclopride.
Synapse (New York, N.Y.) 2006;59(5):260-9.
2006: Sylvie Chalon; Håkan Hall; Wadad Saba; Lucette Garreau; Frédéric Dollé; Christer Halldin; Patrick Emond; Michel Bottlaender; Jean-Bernard Deloye; Julie Helfenbein; Jean-Claude Madelmont; Sylvie Bodard; Zoïa Mincheva; Jean-Claude Besnard; Denis Guilloteau
Pharmacological characterization of (E)-N-(4-fluorobut-2-enyl)-2beta-carbomethoxy-3beta-(4'-tolyl)nortropane (LBT-999) as a highly promising fluorinated ligand for the dopamine transporter.
The Journal of pharmacology and experimental therapeutics 2006;317(1):147-52.
2006: Yuan-Hwa Chou; Christer Halldin; Lars Farde
Clozapine binds preferentially to cortical D1-like dopamine receptors in the primate brain: a PET study.
Psychopharmacology 2006;185(1):29-35.
2006: Frédéric Dollé; Patrick Emond; Sylvie Mavel; Stéphane Demphel; Françoise Hinnen; Zoïa Mincheva; Wadad Saba; Héric Valette; Sylvie Chalon; Christer Halldin; Julie Helfenbein; Joël Legaillard; Jean-Claude Madelmont; Jean-Bernard Deloye; Michel Bottlaender; Denis Guilloteau
Synthesis, radiosynthesis and in vivo preliminary evaluation of [11C]LBT-999, a selective radioligand for the visualisation of the dopamine transporter with PET.
Bioorganic & medicinal chemistry 2006;14(4):1115-25.
2006: Magnus Schou; Judit Sóvágó; Victor W Pike; Balázs Gulyás; Klaus P Bøgesø; Lars Farde; Christer Halldin
Synthesis and positron emission tomography evaluation of three norepinephrine transporter radioligands: [C-11]desipramine, [C-11]talopram and [C-11]talsupram.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2006;8(1):1-8.
2005: Christer Halldin; Johan Lundberg; Judit Sóvágó; Balázs Gulyás; Denis Guilloteau; Johnny Vercouillie; Patrick Emond; Sylvie Chalon; Jari Tarkiainen; Jukka Hiltunen; Lars Farde
[(11)C]MADAM, a new serotonin transporter radioligand characterized in the monkey brain by PET.
Synapse (New York, N.Y.) 2005;58(3):173-83.
2005: Judit Sóvágó; Lars Farde; Christer Halldin; Evgenij Schukin; Magnus Schou; István Laszlovszky; Béla Kiss; Balázs Gulyás
Lack of effect of reserpine-induced dopamine depletion on the binding of the dopamine-D3 selective radioligand, [11C]RGH-1756.
Brain research bulletin 2005;67(3):219-24.
2005: Magnus Schou; Christer Halldin; Victor W Pike; P David Mozley; David Dobson; Robert B Innis; Lars Farde; Håkan Hall
Post-mortem human brain autoradiography of the norepinephrine transporter using (S,S)-[18F]FMeNER-D2.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2005;15(5):517-20.
2005: Johan Lundberg; Ikuo Odano; Hans Olsson; Christer Halldin; Lars Farde
Quantification of 11C-MADAM binding to the serotonin transporter in the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(9):1505-15.
2005: Nicholas Seneca; Bengt Andree; Nils Sjoholm; Magnus Schou; Stefan Pauli; P David Mozley; James B Stubbs; Jeih-San Liow; Judit Sovago; Balázs Gulyás; Robert B Innis; Christer Halldin
Whole-body biodistribution, radiation dosimetry estimates for the PET norepinephrine transporter probe (S,S)-[18F]FMeNER-D2 in non-human primates.
Nuclear medicine communications 2005;26(8):695-700.
2005: Anna Meschaks; Per Lindstrom; Christer Halldin; Lars Farde; Ivanka Savic
Regional reductions in serotonin 1A receptor binding in juvenile myoclonic epilepsy.
Archives of neurology 2005;62(6):946-50.
2005: Julie A McCarron; Sandrine Marchais-Oberwinkler; Victor W Pike; Jari Tarkiainen; Christer Halldin; Judit Sóvagó; Balàzs Gulyas; Håkan V Wikström; Lars Farde
Two C-methyl derivatives of [11C]WAY-100635--effects of an amido alpha-methyl group on metabolism and brain 5-HT1A receptor radioligand behavior in monkey.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2005;7(3):209-19.
2005: Sjoerd J Finnema; Nicholas Seneca; Lars Farde; Evgeny Shchukin; Judit Sóvágó; Balázs Gulyás; Håkan V Wikström; Robert B Innis; John L Neumeyer; Christer Halldin
A preliminary PET evaluation of the new dopamine D2 receptor agonist [11C]MNPA in cynomolgus monkey.
Nuclear medicine and biology 2005;32(4):353-60.
2005: Subroto Ghose; Masahiro Fujita; Paul Morrison; George R. Uhl; Dennis L Murphy; P David Mozley; Magnus Schou; Christer Halldin; Robert B Innis
Specific in vitro binding of (S,S)-[3H]MeNER to norepinephrine transporters.
Synapse (New York, N.Y.) 2005;56(2):100-4.
2005: Balázs Gulyás; Christer Halldin; Adám Vas; Richard B Banati; Evgeny Shchukin; Sjoerd Finnema; Jari Tarkainen; Karoly Tihanyi; Géza Szilágyi; Lars Farde
[11C]vinpocetine: a prospective peripheral benzodiazepine receptor ligand for primate PET studies.
Journal of the neurological sciences 2005;229-230():219-23.
2005: Ming-Rong Zhang; Jun Maeda; Takehito Ito; Takashi Okauchi; Masanao Ogawa; Junko Noguchi; Tetsuya Suhara; Christer Halldin; Kazutoshi Suzuki
Synthesis and evaluation of N-(5-fluoro-2-phenoxyphenyl)-N-(2-[(18)F]fluoromethoxy-d(2)-5-methoxybenzyl)acetamide: a deuterium-substituted radioligand for peripheral benzodiazepine receptor.
Bioorganic & medicinal chemistry 2005;13(5):1811-8.
2005: Nikolaj N Ryzhikov; Nicholas Seneca; Raisa N Krasikova; Natalia A Gomzina; Evgeny Shchukin; Olga S Fedorova; Dmitrij A Vassiliev; Balázs Gulyás; Håkan Hall; Ivanka Savic; Christer Halldin
Preparation of highly specific radioactivity [18F]flumazenil and its evaluation in cynomolgus monkey by positron emission tomography.
Nuclear medicine and biology 2005;32(2):109-16.
2005: Aurelija Jucaite; Elisabeth Fernell; Christer Halldin; Hans Forssberg; Lars Farde
Reduced midbrain dopamine transporter binding in male adolescents with attention-deficit/hyperactivity disorder: association between striatal dopamine markers and motor hyperactivity.
Biological psychiatry 2005;57(3):229-38.
2005: Sandrine Marchais-Oberwinkler; Bartek Nowicki; Victor W Pike; Christer Halldin; Johan Sandell; Yuan-Hwa Chou; Balazs Gulyas; Lise T Brennum; Lars Farde; Håkan V Wikström
N-oxide analogs of WAY-100635: new high affinity 5-HT(1A) receptor antagonists.
Bioorganic & medicinal chemistry 2005;13(3):883-93.
2005: Nina Erixon-Lindroth; Lars Farde; Tarja-Brita Robins Wahlin; Judit Sovago; Christer Halldin; Lars Bäckman
The role of the striatal dopamine transporter in cognitive aging.
Psychiatry research 2005;138(1):1-12.
2004: Zsolt Cselényi; Johan Lundberg; Christer Halldin; Lars Farde; Balázs Gulyás
Joint explorative analysis of neuroreceptor subsystems in the human brain: application to receptor-transporter correlation using PET data.
Neurochemistry international 2004;45(5):773-81.
2004: Judit Sóvágó; Lars Farde; Christer Halldin; Oliver Langer; István Laszlovszky; Béla Kiss; Balázs Gulyás
Positron emission tomographic evaluation of the putative dopamine-D3 receptor ligand, [11C]RGH-1756 in the monkey brain.
Neurochemistry international 2004;45(5):609-17.
2004: Mirjam Talvik; Anna-Lena Nordström; Niels-Erik Larsen; Aurelija Jucaite; Simon Cervenka; Christer Halldin; Lars Farde
A cross-validation study on the relationship between central D2 receptor occupancy and serum perphenazine concentration.
Psychopharmacology 2004;175(2):148-53.
2004: Magnus Schou; Christer Halldin; Judit Sóvágó; Victor W Pike; Håkan Hall; Balázs Gulyás; P David Mozley; David Dobson; Evgeny Shchukin; Robert B Innis; Lars Farde
PET evaluation of novel radiofluorinated reboxetine analogs as norepinephrine transporter probes in the monkey brain.
Synapse (New York, N.Y.) 2004;53(2):57-67.
2004: Katarina Varnäs; Christer Halldin; Håkan Hall
Autoradiographic distribution of serotonin transporters and receptor subtypes in human brain.
Human brain mapping 2004;22(3):246-60.
2004: Hans Olsson; Christer Halldin; Lars Farde
Differentiation of extrastriatal dopamine D2 receptor density and affinity in the human brain using PET.
NeuroImage 2004;22(2):794-803.
2004: Fumihiko Yasuno; Tetsuya Suhara; Yoshiro Okubo; Yasuhiko Sudo; Makoto Inoue; Tetsuya Ichimiya; Akihiro Takano; Kazuhiko Nakayama; Christer Halldin; Lars Farde
Low dopamine d(2) receptor binding in subregions of the thalamus in schizophrenia.
The American journal of psychiatry 2004;161(6):1016-22.
2004: Ivanka Savic; Per Lindström; Balázs Gulyás; Christer Halldin; B Andrée; Lars Farde
Limbic reductions of 5-HT1A receptor binding in human temporal lobe epilepsy.
Neurology 2004;62(8):1343-51.
2004: Thomas Balle; Christer Halldin; Linus Andersen; Lene Hjorth Alifrangis; Lassina Badolo; Klaus Gjervig Jensen; Yuan-Wha Chou; Kim Andersen; Jens Perregaard; Lars Farde
New alpha(1)-adrenoceptor antagonists derived from the antipsychotic sertindole - carbon-11 labelling and pet examination of brain uptake in the cynomolgus monkey.
Nuclear medicine and biology 2004;31(3):327-36.
2004: Anna Kirstine Larsen; Lise T Brennum; J Egebjerg; Connie Sánchez; Christer Halldin; P H Andersen
Selectivity of (3)H-MADAM binding to 5-hydroxytryptamine transporters in vitro and in vivo in mice; correlation with behavioural effects.
British journal of pharmacology 2004;141(6):1015-23.
2004: Christer Halldin; B Gulyás; Lars Farde
PET for drug development.
Ernst Schering Research Foundation workshop 2004;(48):95-109.
2004: Julie A McCarron; Victor W Pike; Christer Halldin; Johan Sandell; Judit Sóvágó; Balàsz Gulyas; Zsolt Cselényi; Håkan V Wikström; Sandrine Marchais-Oberwinkler; Bartek Nowicki; Frédéric Dollé; Lars Farde
The pyridinyl-6 position of WAY-100635 as a site for radiofluorination--effect on 5-HT1A receptor radioligand behavior in vivo.
Molecular imaging and biology : MIB : the official publication of the Academy of Molecular Imaging 2004;6(1):17-26.
2004: Olli Eskola; Tove Grönroos; Jörgen Bergman; Merja Haaparanta; Päivi Marjamäki; Pertti Lehikoinen; Sarita Forsback; Oliver Langer; Françoise Hinnen; Frédéric Dollé; Christer Halldin; Olof Solin
A novel electrophilic synthesis and evaluation of medium specific radioactivity (1R,2S)-4-[18F]fluorometaraminol, a tracer for the assessment of cardiac sympathetic nerve integrity with PET.
Nuclear medicine and biology 2004;31(1):103-10.
2003: Mirjam Talvik; Anna-Lena Nordström; Hans Olsson; Christer Halldin; Lars Farde
Decreased thalamic D2/D3 receptor binding in drug-naive patients with schizophrenia: a PET study with [11C]FLB 457.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2003;6(4):361-70.
2003: Victor W Pike; Christer Halldin; Kenji Nobuhara; Jukka Hiltunen; Rachel S Mulligan; Carl-Gunnar Swahn; Per Karlsson; Hans Olsson; Susan P Hume; Ella Hirani; Jaqueline Whalley; Lyn S Pilowsky; Stig Larsson; Per-Olof Schnell; Peter J Ell; Lars Farde
Radioiodinated SB 207710 as a radioligand in vivo: imaging of brain 5-HT4 receptors with SPET.
European journal of nuclear medicine and molecular imaging 2003;30(11):1520-8.
2003: Magnus Schou; Christer Halldin; Judit Sóvágó; Victor W Pike; Balázs Gulyás; P David Mozley; David P Johnson; Håkan Hall; Robert B Innis; Lars Farde
Specific in vivo binding to the norepinephrine transporter demonstrated with the PET radioligand, (S,S)-[11C]MeNER.
Nuclear medicine and biology 2003;30(7):707-14.
2003: Christer Halldin; Nina Erixon-Lindroth; Stefan Pauli; Yuan-Hwa Chou; Yoshiro Okubo; Per Karlsson; Camilla Lundkvist; Hans Olsson; Denis Guilloteau; Patrick Emond; Lars Farde
[(11)C]PE2I: a highly selective radioligand for PET examination of the dopamine transporter in monkey and human brain.
European journal of nuclear medicine and molecular imaging 2003;30(9):1220-30.
2003: Katarina Varnäs; Christer Halldin; Victor W Pike; Håkan Hall
Distribution of 5-HT4 receptors in the postmortem human brain--an autoradiographic study using [125I]SB 207710.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 2003;13(4):228-34.
2003: Mylène Karramkam; Françoise Hinnen; Myriam Berrehouma; Christophe Hlavacek; Françoise Vaufrey; Christer Halldin; Julie A McCarron; Victor W Pike; Frédéric Dollé
Synthesis of a [6-pyridinyl-18F]-labelled fluoro derivative of WAY-100635 as a candidate radioligand for brain 5-HT1A receptor imaging with PET.
Bioorganic & medicinal chemistry 2003;11(13):2769-82.
2003: Bengt Andrée; Ann Hedman; Seth-Olov Thorberg; Dag Nilsson; Christer Halldin; Lars Farde
Positron emission tomographic analysis of dose-dependent NAD-299 binding to 5-hydroxytryptamine-1A receptors in the human brain.
Psychopharmacology 2003;167(1):37-45.
2003: Yuan-Hwa Chou; Christer Halldin; Lars Farde
Occupancy of 5-HT1A receptors by clozapine in the primate brain: a PET study.
Psychopharmacology 2003;166(3):234-40.
2003: Sylvie Chalon; Jari Tarkiainen; Lucette Garreau; Håkan Hall; Patrick Emond; Johnny Vercouillie; Lars Farde; Philippe Dasse; Katarina Varnas; Jean-Claude Besnard; Christer Halldin; Denis Guilloteau
Pharmacological characterization of N,N-dimethyl-2-(2-amino-4-methylphenyl thio)benzylamine as a ligand of the serotonin transporter with high affinity and selectivity.
The Journal of pharmacology and experimental therapeutics 2003;304(1):81-7.
2002: Johan Sandell; Meixiang Yu; Patrick Emond; Lucette Garreau; Sylvie Chalon; Kjell Någren; Denis Guilloteau; Christer Halldin
Synthesis, radiolabeling and preliminary biological evaluation of radiolabeled 5-methyl-6-nitroquipazine, a potential radioligand for the serotonin transporter.
Bioorganic & medicinal chemistry letters 2002;12(24):3611-3.
2002: Balázs Gulyás; Christer Halldin; Johan Sandell; Per Karlsson; Judit Sóvágó; Egon Kárpáti; Béla Kiss; Adám Vas; Zsolt Cselényi; Lars Farde
PET studies on the brain uptake and regional distribution of [11C]vinpocetine in human subjects.
Acta neurologica Scandinavica 2002;106(6):325-32.
2002: Adám Vas; Judit Sóvágó; Christer Halldin; Johan Sandell; Per Karlsson; Egon Kárpáti; Béla Kiss; Zsolt Cselényi; Lars Farde; Balázs Gulyás
[Cerebral uptake and regional distribution of [11C]-vinpocetin after intravenous administration to healthy men: a PET study].
Orvosi hetilap 2002;143(47):2631-6.
2002: P Bartenstein; S Asenbaum; A Catafau; Christer Halldin; L Pilowski; A Pupi; K Tatsch
European Association of Nuclear Medicine procedure guidelines for brain imaging using [(18)F]FDG.
European journal of nuclear medicine and molecular imaging 2002;29(10):BP43-8.
2002: K Tatsch; S Asenbaum; P Bartenstein; A Catafau; Christer Halldin; LS Pilowsky; A Pupi
European Association of Nuclear Medicine procedure guidelines for brain perfusion SPET using (99m)Tc-labelled radiopharmaceuticals.
European journal of nuclear medicine and molecular imaging 2002;29(10):BP36-42.
2002: K Tatsch; S Asenbaum; P Bartenstein; A Catafau; Christer Halldin; LS Pilowsky; A Pupi
European Association of Nuclear Medicine procedure guidelines for brain neurotransmission SPET using (123)I-labelled dopamine D(2) transporter ligands.
European journal of nuclear medicine and molecular imaging 2002;29(10):BP30-5.
2002: K Tatsch; S Asenbaum; P Bartenstein; A Catafau; Christer Halldin; LS Pilowsky; A Pupi
European Association of Nuclear Medicine procedure guidelines for brain neurotransmission SPET using (123)I-labelled dopamine D(2) receptor ligands.
European journal of nuclear medicine and molecular imaging 2002;29(10):BP23-9.
2002: Balázs Gulyás; Adám Vas; Christer Halldin; Judit Sóvágó; Johan Sandell; Hans Olsson; Anna Fredriksson; Sharon Stone-Elander; Lars Farde
Cerebral uptake of [ethyl-11C]vinpocetine and 1-[11C]ethanol in cynomolgous monkeys: a comparative preclinical PET study.
Nuclear medicine and biology 2002;29(7):753-9.
2002: Johan Sandell; Christer Halldin; Judith Sovago; Yuan-Hwa Chou; Balázs Gulyás; Meixiang Yu; Patrick Emond; Kjell Någren; Denis Guilloteau; Lars Farde
PET examination of [(11)C]5-methyl-6-nitroquipazine, a radioligand for visualization of the serotonin transporter.
Nuclear medicine and biology 2002;29(6):651-6.
2002: Balázs Gulyás; Christer Halldin; Judit Sóvágó; Johan Sandell; Zsolt Cselényi; Adám Vas; Béla Kiss; Egon Kárpáti; Lars Farde
Drug distribution in man: a positron emission tomography study after oral administration of the labelled neuroprotective drug vinpocetine.
European journal of nuclear medicine and molecular imaging 2002;29(8):1031-8.
2002: Svante Nyberg; Hans Olsson; Ulrika Nilsson; Eli Maehlum; Christer Halldin; Lars Farde
Low striatal and extra-striatal D2 receptor occupancy during treatment with the atypical antipsychotic sertindole.
Psychopharmacology 2002;162(1):37-41.
2002: Antje Drews; Hans-Jürgen Pietzsch; Rosemarie Syhre; Sepp Seifert; K Varnäs; Håkan Hall; Christer Halldin; Werner Kraus; P Karlsson; C Johnsson; Hartmut Spies; Bernd Johannsen
Synthesis and biological evaluation of technetium(III) mixed-ligand complexes with high affinity for the cerebral 5-HT(1A) receptor and the alpha1-adrenergic receptor.
Nuclear medicine and biology 2002;29(4):389-98.
2002: I Heimbold; Antje Drews; Marion Kretzschmar; K Varnäs; Håkan Hall; Christer Halldin; Rosemarie Syhre; Werner Kraus; Hans-Jürgen Pietzsch; Sepp Seifert; Peter Brust; Bernd Johannsen
Synthesis, biological and autoradiographic evaluation of a novel Tc-99m radioligand derived from WAY 100635 with high affinity for the 5-HT(1A) receptor and the alpha1-adrenergic receptor.
Nuclear medicine and biology 2002;29(4):375-87.
2002: Per Karlsson; Lars Farde; Christer Halldin; Göran C Sedvall
PET study of D(1) dopamine receptor binding in neuroleptic-naive patients with schizophrenia.
The American journal of psychiatry 2002;159(5):761-7.
2002: Patrick Emond; Johnny Vercouillie; Robert B Innis; Sylvie Chalon; Sylvie Mavel; Yves Frangin; Christer Halldin; Jean-Claude Besnard; Denis Guilloteau
Substituted diphenyl sulfides as selective serotonin transporter ligands: synthesis and in vitro evaluation.
Journal of medicinal chemistry 2002;45(6):1253-8.
2002: Svante Nyberg; Yuan-Hwa Chou; Christer Halldin
Saturation of striatal D(2) dopamine receptors by clozapine.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2002;5(1):11-6.
2002: Oliver Langer; Christer Halldin
PET and SPET tracers for mapping the cardiac nervous system.
European journal of nuclear medicine and molecular imaging 2002;29(3):416-34.
2002: Bengt Andrée; Christer Halldin; Victor W Pike; Roger Gunn; Hans Olsson; Lars Farde
The PET radioligand [carbonyl-(11)C]desmethyl-WAY-100635 binds to 5-HT(1A) receptors and provides a higher radioactive signal than [carbonyl-(11)C]WAY-100635 in the human brain.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2002;43(3):292-303.
2002: Håkan Hall; Katarina Varnäs; Johan Sandell; Christer Halldin; Lars Farde; Adám Vas; Egon Kárpáti; Balázs Gulyás
Autoradiographic evaluation of [11C]vinpocetine binding in the human postmortem brain.
Acta biologica Hungarica 2002;53(1-2):59-66.
2002: Johan Sandell; Christer Halldin; Yuan-Hwa Chou; Carl-Gunnar Swahn; Seth-Olov Thorberg; Lars Farde
PET-examination and metabolite evaluation in monkey of [(11)C]NAD-299, a radioligand for visualisation of the 5-HT(1A) receptor.
Nuclear medicine and biology 2002;29(1):39-45.
2002: Tetsuya Suhara; Yoshiro Okubo; Fumihiko Yasuno; Yasuhiko Sudo; Makoto Inoue; Tetsuya Ichimiya; Yoshifumi Nakashima; Kazuhiko Nakayama; Shuji Tanada; Kazutoshi Suzuki; Christer Halldin; Lars Farde
Decreased dopamine D2 receptor binding in the anterior cingulate cortex in schizophrenia.
Archives of general psychiatry 2002;59(1):25-30.
2001: Christer Halldin; B Gulyás; Lars Farde
PET studies with carbon-11 radioligands in neuropsychopharmacological drug development.
Current pharmaceutical design 2001;7(18):1907-29.
2001: Yasuhiko Sudo; Tetsuya Suhara; Makoto Inoue; Hiroshi Ito; Kazutoshi Suzuki; T Saijo; Christer Halldin; Lars Farde
Reproducibility of [11 C]FLB 457 binding in extrastriatal regions.
Nuclear medicine communications 2001;22(11):1215-21.
2001: Christer Halldin
Serotonin 5-HT1A receptor imaging in the human brain with positron-emission tomography: coordination and the standardization and dissemination of methodology.
Journal of clinical pharmacology 2001;Suppl():95S.
2001: Christer Halldin; Balázs Gulyás; O Langer; Lars Farde
Brain radioligands--state of the art and new trends.
The quarterly journal of nuclear medicine : official publication of the Italian Association of Nuclear Medicine (AIMN) [and] the International Association of Radiopharmacology (IAR) 2001;45(2):139-52.
2001: Mirjam Talvik; Anna-Lena Nordström; Svante Nyberg; Hans Olsson; Christer Halldin; Lars Farde
No support for regional selectivity in clozapine-treated patients: a PET study with [(11)C]raclopride and [(11)C]FLB 457.
The American journal of psychiatry 2001;158(6):926-30.
2001: S Marchais; Bartek Nowicki; Håkan V Wikström; Lise T Brennum; Christer Halldin; Victor W Pike
Short and efficient syntheses of analogues of WAY-100635: new and potent 5-HT1A receptor antagonists.
Bioorganic & medicinal chemistry 2001;9(3):695-702.
2001: O Langer; Frédéric Dollé; Héric Valette; Christer Halldin; Françoise Vaufrey; Chantal Fuseau; Christine Coulon; Michèle Ottaviani; K Någren; Michel Bottlaender; B Maziére; Christian Crouzel
Synthesis of high-specific-radioactivity 4- and 6-[18F]fluorometaraminol-PET tracers for the adrenergic nervous system of the heart.
Bioorganic & medicinal chemistry 2001;9(3):677-94.
2001: Hiroshi Ito; Y Sudo; T Suhara; Y Okubo; Christer Halldin; Lars Farde
Error analysis for quantification of [(11)C]FLB 457 binding to extrastriatal D(2) dopamine receptors in the human brain.
NeuroImage 2001;13(3):531-9.
2001: Johan Sandell; Christer Halldin; Victor W Pike; Yuan-Hwa Chou; Katarina Varnäs; Håkan Hall; S Marchais; Bartek Nowicki; Håkan V Wikström; Carl-Gunnar Swahn; Lars Farde
New halogenated [11C]WAY analogues, [11C]6FPWAY and [11C]6BPWAY--radiosynthesis and assessment as radioligands for the study of brain 5-HT1A receptors in living monkey.
Nuclear medicine and biology 2001;28(2):177-85.
2001: Victor W Pike; Christer Halldin; H V Wikström
Radioligands for the study of brain 5-HT1A receptors in vivo.
Progress in medicinal chemistry 2001;38():189-247.
2001: K Nobuhara; Lars Farde; Christer Halldin; Per Karlsson; Carl-Gunnar Swahn; Hans Olsson; Kim A Bergström; Stig A Larsson; Per-Olof Schnell; DW McPherson; A Savonen; Jukka Hiltunen; Göran C Sedvall
SPET imaging of central muscarinic acetylcholine receptors with iodine-123 labelled E-IQNP and Z-IQNP.
European journal of nuclear medicine 2001;28(1):13-24.
2000: Håkan Hall; Lars Farde; Christer Halldin; Camilla Lundkvist; Göran C Sedvall
Autoradiographic localization of 5-HT(2A) receptors in the human brain using [(3)H]M100907 and [(11)C]M100907.
Synapse (New York, N.Y.) 2000;38(4):421-31.
2000: O Langer; Christer Halldin; Y Chou; Johan Sandell; Carl-Gunnar Swahn; Kjell Någren; Roberto Perrone; Francesco Berardi; Marcello Leopoldo; Lars Farde
Carbon-11 pb-12: an attempt to visualize the dopamine d(4) receptor in the primate brain with positron emission tomography.
Nuclear medicine and biology 2000;27(8):707-14.
2000: Yuan-Hwa Chou; Christer Halldin; Lars Farde
Effect of amphetamine on extrastriatal D2 dopamine receptor binding in the primate brain: a PET study.
Synapse (New York, N.Y.) 2000;38(2):138-43.
2000: Bengt Andrée; Christer Halldin; Seth-Olov Thorberg; Johan Sandell; Lars Farde
Use of PET and the radioligand [carbonyl-(11)C]WAY-100635 in psychotropic drug development.
Nuclear medicine and biology 2000;27(5):515-21.
2000: Victor W Pike; Christer Halldin; Håkan V Wikström; S Marchais; Julie A McCarron; Johan Sandell; Bartek Nowicki; Carl-Gunnar Swahn; Safiye Osman; Susan P Hume; M Constantinou; Bengt Andrée; Lars Farde
Radioligands for the study of brain 5-HT(1A) receptors in vivo--development of some new analogues of way.
Nuclear medicine and biology 2000;27(5):449-55.
2000: Lars H Pinborg; Charlotte Videbaek; Gitte Moos Knudsen; C G Swahn; Christer Halldin; Lars Friberg; Olaf B Paulson; NA Lassen
Dopamine D(2) receptor quantification in extrastriatal brain regions using [(123)I]epidepride with bolus/infusion.
Synapse (New York, N.Y.) 2000;36(4):322-9.
2000: Valtteri Kaasinen; Kjell Någren; Jarmo Hietala; Vesa Oikonen; Harry Vilkman; Lars Farde; Christer Halldin; Juha O Rinne
Extrastriatal dopamine D2 and D3 receptors in early and advanced Parkinson's disease.
Neurology 2000;54(7):1482-7.
2000: O Langer; Héric Valette; Frédéric Dollé; Christer Halldin; Christian Loc'h; Chantal Fuseau; Christine Coulon; Michèle Ottaviani; Michel Bottlaender; B Mazière; Christian Crouzel
High specific radioactivity (1R,2S)-4-[(18)F]fluorometaraminol: a PET radiotracer for mapping sympathetic nerves of the heart.
Nuclear medicine and biology 2000;27(3):233-8.
2000: Lars Bäckman; N Ginovart; R A Dixon; Tarja-Brita Robins Wahlin; Ake Wahlin; Christer Halldin; Lars Farde
Age-related cognitive deficits mediated by changes in the striatal dopamine system.
The American journal of psychiatry 2000;157(4):635-7.
2000: Lars Farde; Bengt Andrée; N Ginovart; Christer Halldin; Seth-Olov Thorberg
PET-Determination of robalzotan (NAD-299) induced 5-HT(1A) receptor occupancy in the monkey brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2000;22(4):422-9.
2000: M Talvik-Lotfi; Svante Nyberg; Anna-Lena Nordström; H Ito; Christer Halldin; F Brunner; Lars Farde
High 5HT2A receptor occupancy in M100907-treated schizophrenic patients.
Psychopharmacology 2000;148(4):400-3.
2000: K Nobuhara; Christer Halldin; Håkan Hall; Per Karlsson; Lars Farde; Jukka Hiltunen; DW McPherson; A Savonen; Kim A Bergström; Stefan Pauli; Carl-Gunnar Swahn; Stig A Larsson; Per-Olof Schnell; Göran C Sedvall
Z-IQNP: a potential radioligand for SPECT imaging of muscarinic acetylcholine receptors in Alzheimer's disease.
Psychopharmacology 2000;149(1):45-55.
2000: Kim A Bergström; M Yu; Jyrki T Kuikka; KK Akerman; Jukka Hiltunen; J Lehtonen; Christer Halldin; Jari Tiihonen
Metabolism of [123I]epidepride may affect brain dopamine D2 receptor imaging with single-photon emission tomography.
European journal of nuclear medicine 2000;27(2):206-8.
2000: Anissa Abi-Dargham; Diana Martinez; Osama Mawlawi; Norman Simpson; Dah-Ren Hwang; Mark Slifstein; S Anjilvel; J Pidcock; Ning-Ning Guo; Ilise Lombardo; J John Mann; Ronald L Van Heertum; C Foged; Christer Halldin; Marc Laruelle
Measurement of striatal and extrastriatal dopamine D1 receptor binding potential with [11C]NNC 112 in humans: validation and reproducibility.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2000;20(2):225-43.
2000: MK Osterlund; Christer Halldin; Yasmin L Hurd
Effects of chronic 17beta-estradiol treatment on the serotonin 5-HT(1A) receptor mRNA and binding levels in the rat brain.
Synapse (New York, N.Y.) 2000;35(1):39-44.
1999: Y Okubo; H Olsson; H Ito; M Lofti; T Suhara; Christer Halldin; Lars Farde
PET mapping of extrastriatal D2-like dopamine receptors in the human brain using an anatomic standardization technique and [11C]FLB 457.
NeuroImage 1999;10(6):666-74.
1999: Kim A Bergström; Christer Halldin; A Savonen; Y Okubo; Jukka Hiltunen; K Nobuhara; Carl-Gunnar Swahn; Per Karlsson; D McPherson; Furn F Knapp; S Larsson; Per-Olof Schnell; Lars Farde
Iodine-123 labelled Z-(R,R)-IQNP: a potential radioligand for visualization of M(1 )and M(2) muscarinic acetylcholine receptors in Alzheimer's disease.
European journal of nuclear medicine 1999;26(11):1482-5.
1999: Balázs Gulyás; Christer Halldin; Per Karlsson; Y H Chou; Carl-Gunnar Swahn; P Bönöck; M Paróczai; Lars Farde
Brain uptake and plasma metabolism of [11C]vinpocetine: a preliminary PET study in a cynomolgus monkey.
Journal of neuroimaging : official journal of the American Society of Neuroimaging 1999;9(4):217-22.
1999: Hans Olsson; Christer Halldin; Carl-Gunnar Swahn; Lars Farde
Quantification of [11C]FLB 457 binding to extrastriatal dopamine receptors in the human brain.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1999;19(10):1164-73.
1999: Yuan-Hwa Chou; Per Karlsson; Christer Halldin; Hans Olsson; Lars Farde
A PET study of D(1)-like dopamine receptor ligand binding during altered endogenous dopamine levels in the primate brain.
Psychopharmacology 1999;146(2):220-7.
1999: Balázs Gulyás; Christer Halldin; Per Karlsson; Y H Chou; Carl-Gunnar Swahn; Péter Bönöczk; Lars Farde
[Cerebral uptake and metabolism of (11C) Vinpocetine in monkeys: PET studies].
Orvosi hetilap 1999;140(30):1687-91.
1999: O Langer; Christer Halldin; Frédéric Dollé; Carl-Gunnar Swahn; Hans Olsson; Per Karlsson; Håkan Hall; Johan Sandell; Camilla Lundkvist; Françoise Vaufrey; Christian Loc'h; Christian Crouzel; B Mazière; Lars Farde
Carbon-11 epidepride: a suitable radioligand for PET investigation of striatal and extrastriatal dopamine D2 receptors.
Nuclear medicine and biology 1999;26(5):509-18.
1999: Camilla Lundkvist; Christian Loc'h; Christer Halldin; Michel Bottlaender; Michèle Ottaviani; Christine Coulon; Chantal Fuseau; C Mathis; Lars Farde; B Mazière
Characterization of bromine-76-labelled 5-bromo-6-nitroquipazine for PET studies of the serotonin transporter.
Nuclear medicine and biology 1999;26(5):501-7.
1999: Julie Helfenbein; Johan Sandell; Christer Halldin; Sylvie Chalon; Patrick Emond; Y Okubo; Yuan-Hwa Chou; Yves Frangin; L Douziech; L Gareau; Carl-Gunnar Swahn; Jean-Claude Besnard; Lars Farde; Denis Guilloteau
PET examination of three potent cocaine derivatives as specific radioligands for the serotonin transporter.
Nuclear medicine and biology 1999;26(5):491-9.
1999: Bengt Andrée; Seth-Olov Thorberg; Christer Halldin; Lars Farde
Pindolol binding to 5-HT1A receptors in the human brain confirmed with positron emission tomography.
Psychopharmacology 1999;144(3):303-5.
1999: Svante Nyberg; B Eriksson; G Oxenstierna; Christer Halldin; Lars Farde
Suggested minimal effective dose of risperidone based on PET-measured D2 and 5-HT2A receptor occupancy in schizophrenic patients.
The American journal of psychiatry 1999;156(6):869-75.
1999: Camilla Lundkvist; Christer Halldin; Carl-Gunnar Swahn; N Ginovart; Lars Farde
Different brain radioactivity curves in a PET study with [11C]beta-CIT labelled in two different positions.
Nuclear medicine and biology 1999;26(4):343-50.
1999: Anissa Abi-Dargham; Norman Simpson; Lawrence S Kegeles; Ramin V Parsey; Dah-Ren Hwang; S Anjilvel; Yolanda Zea-Ponce; Ilise Lombardo; Ronald L Van Heertum; J John Mann; C Foged; Christer Halldin; Marc Laruelle
PET studies of binding competition between endogenous dopamine and the D1 radiotracer [11C]NNC 756.
Synapse (New York, N.Y.) 1999;32(2):93-109.
1999: Johan Sandell; Christer Halldin; Håkan Hall; Seth-Olov Thorberg; T Werner; Daniel Sohn; Göran C Sedvall; Lars Farde
Radiosynthesis and autoradiographic evaluation of [11C]NAD-299, a radioligand for visualization of the 5-HT1A receptor.
Nuclear medicine and biology 1999;26(2):159-64.
1999: N Ginovart; Lars Farde; Christer Halldin; Carl-Gunnar Swahn
Changes in striatal D2-receptor density following chronic treatment with amphetamine as assessed with PET in nonhuman primates.
Synapse (New York, N.Y.) 1999;31(2):154-62.
1999: H Ito; Y Okubo; Christer Halldin; Lars Farde
Mapping of central D2 dopamine receptors in man using [11C]raclopride: PET with anatomic standardization technique.
NeuroImage 1999;9(2):235-42.
1999: H Ito; Christer Halldin; Lars Farde
Localization of 5-HT1A receptors in the living human brain using [carbonyl-11C]WAY-100635: PET with anatomic standardization technique.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(1):102-9.
1999: Håkan Hall; Christer Halldin; Denis Guilloteau; S Chalon; Patrick Emond; Jean-Claude Besnard; Lars Farde; G Sedvall
Visualization of the dopamine transporter in the human brain postmortem with the new selective ligand [125I]PE2I.
NeuroImage 1999;9(1):108-16.
1998: Christer Halldin; C Foged; Yuan-Hwa Chou; Per Karlsson; Carl-Gunnar Swahn; Johan Sandell; Göran C Sedvall; Lars Farde
Carbon-11-NNC 112: a radioligand for PET examination of striatal and neocortical D1-dopamine receptors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(12):2061-8.
1998: Håkan Hall; Christer Halldin; Lars Farde; Göran C Sedvall
Whole hemisphere autoradiography of the postmortem human brain.
Nuclear medicine and biology 1998;25(8):715-9.
1998: Lars Farde; H Ito; Carl-Gunnar Swahn; Victor W Pike; Christer Halldin
Quantitative analyses of carbonyl-carbon-11-WAY-100635 binding to central 5-hydroxytryptamine-1A receptors in man.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(11):1965-71.
1998: H Ito; J Hietala; G Blomqvist; Christer Halldin; Lars Farde
Comparison of the transient equilibrium and continuous infusion method for quantitative PET analysis of [11C]raclopride binding.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(9):941-50.
1998: Bengt Andrée; Svante Nyberg; H Ito; N Ginovart; F Brunner; F Jaquet; Christer Halldin; Lars Farde
Positron emission tomographic analysis of dose-dependent MDL 100,907 binding to 5-hydroxytryptamine-2A receptors in the human brain.
Journal of clinical psychopharmacology 1998;18(4):317-23.
1998: Anna-Lena Nordström; H Olsson; Christer Halldin
A PET study of D2 dopamine receptor density at different phases of the menstrual cycle.
Psychiatry research 1998;83(1):1-6.
1998: C Foged; Christer Halldin; Carl-Gunnar Swahn; N Ginovart; Per Karlsson; Camilla Lundkvist; Lars Farde
[11C]NNC 22-0215, a metabolically stable dopamine D1 radioligand for PET.
Nuclear medicine and biology 1998;25(5):503-8.
1998: Patrick Emond; Lars Farde; Sylvie Chalon; Catherine Belzung; V Mauclaire; J P Chiron; Christer Halldin; Jean-Claude Besnard; Denis Guilloteau
Toxicity, mutagenicity, and behavioral effects of beta-CIT, a ligand for dopamine transporter exploration by SPECT.
Nuclear medicine and biology 1998;25(4):405-9.
1998: Ivanka Savic; G Blomqvist; Christer Halldin; JE Litton; B Gulyas
Regional increases in [11C]flumazenil binding after epilepsy surgery.
Acta neurologica Scandinavica 1998;97(5):279-86.
1998: Jyrki T Kuikka; Jean-Louis Baulieu; Jukka Hiltunen; Christer Halldin; Kim A Bergström; Lars Farde; Patrick Emond; Sylvie Chalon; M Yu; T Nikula; T Laitinen; Jari Karhu; Erkki Tupala; Tero Hallikainen; V Kolehmainen; L Mauclaire; Bernard Maziere; Jari Tiihonen; Denis Guilloteau
Pharmacokinetics and dosimetry of iodine-123 labelled PE2I in humans, a radioligand for dopamine transporter imaging.
European journal of nuclear medicine 1998;25(5):531-4.
1998: Safiye Osman; Camilla Lundkvist; Victor W Pike; Christer Halldin; Julie A McCarron; Carl-Gunnar Swahn; Lars Farde; N Ginovart; Sajinder K Luthra; Roger Gunn; Christopher J Bench; Peter A Sargent; Paul M Grasby
Characterisation of the appearance of radioactive metabolites in monkey and human plasma from the 5-HT1A receptor radioligand, [carbonyl-11C]WAY-100635--explanation of high signal contrast in PET and an aid to biomathematical modelling.
Nuclear medicine and biology 1998;25(3):215-23.
1998: Kim A Bergström; Christer Halldin; Jukka Hiltunen; Carl-Gunnar Swahn; H Ito; N Ginovart; Håkan Hall; DW McPherson; Furn F Knapp; S Larsson; Per-Olof Schnell; Lars Farde
Evaluation and metabolite studies of 125I- and 123I-labelled E-(R,R)-IQNP: potential radioligands for visualization of M1 muscarinic acetylcholine receptors in brain.
Nuclear medicine and biology 1998;25(3):209-14.
1998: Victor W Pike; Christer Halldin; Julie A McCarron; Camilla Lundkvist; Ella Hirani; Hans Olsson; Susan P Hume; Per Karlsson; Safiye Osman; Carl-Gunnar Swahn; Håkan Hall; Håkan V Wikström; M Mensonidas; K G Poole; Lars Farde
[carbonyl-11C]Desmethyl-WAY-100635 (DWAY) is a potent and selective radioligand for central 5-HT1A receptors in vitro and in vivo.
European journal of nuclear medicine 1998;25(4):338-46.
1998: Svante Nyberg; U Nilsson; Y Okubo; Christer Halldin; Lars Farde
Implications of brain imaging for the management of schizophrenia.
International clinical psychopharmacology 1998;13 Suppl 3():S15-20.
1998: H Ito; Svante Nyberg; Christer Halldin; Camilla Lundkvist; Lars Farde
PET imaging of central 5-HT2A receptors with carbon-11-MDL 100,907.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1998;39(1):208-14.
1998: Jukka Hiltunen; KK Akerman; Jyrki T Kuikka; Kim A Bergström; Christer Halldin; T Nikula; Pirkko Räsänen; Jari Tiihonen; M Vauhkonen; Jari Karhu; J Kupila; Esko Länsimies; Lars Farde
Iodine-123 labeled nor-beta-CIT as a potential tracer for serotonin transporter imaging in the human brain with single-photon emission tomography.
European journal of nuclear medicine 1998;25(1):19-23.
1997: Lars Farde; T Suhara; Svante Nyberg; P Karlsson; Y Nakashima; J Hietala; Christer Halldin
A PET-study of [11C]FLB 457 binding to extrastriatal D2-dopamine receptors in healthy subjects and antipsychotic drug-treated patients.
Psychopharmacology 1997;133(4):396-404.
1997: I Günther; Håkan Hall; Christer Halldin; Carl-Gunnar Swahn; Lars Farde; Göran C Sedvall
[125I] beta-CIT-FE and [125I] beta-CIT-FP are superior to [125I] beta-CIT for dopamine transporter visualization: autoradiographic evaluation in the human brain.
Nuclear medicine and biology 1997;24(7):629-34.
1997: Camilla Lundkvist; Christer Halldin; N Ginovart; Carl-Gunnar Swahn; Lars Farde
[18F] beta-CIT-FP is superior to [11C] beta-CIT-FP for quantitation of the dopamine transporter.
Nuclear medicine and biology 1997;24(7):621-7.
1997: Svante Nyberg; Lars Farde; Christer Halldin
Delayed normalization of central D2 dopamine receptor availability after discontinuation of haloperidol decanoate. Preliminary findings.
Archives of general psychiatry 1997;54(10):953-8.
1997: C Foged; Christer Halldin; Christian Loc'h; B Mazière; Stefan Pauli; M Maziére; H C Hansen; T Suhara; Carl-Gunnar Swahn; Per Karlsson; Lars Farde
Bromine-76 and carbon-11 labelled NNC 13-8199, metabolically stable benzodiazepine receptor agonists as radioligands for positron emission tomography.
European journal of nuclear medicine 1997;24(10):1261-7.
1997: Lars Farde; N Ginovart; H Ito; Camilla Lundkvist; Victor W Pike; Julie A McCarron; Christer Halldin
PET-characterization of [carbonyl-11C]WAY-100635 binding to 5-HT1A receptors in the primate brain.
Psychopharmacology 1997;133(2):196-202.
1997: Håkan Hall; Christer Halldin; E Jerning; M Osterlund; Lars Farde; Göran C Sedvall
Autoradiographic comparison of [125I]epidepride and [125I]NCQ 298 binding to human brain extrastriated dopamine receptors.
Nuclear medicine and biology 1997;24(5):389-93.
1997: Bengt Andrée; Christer Halldin; M Vrijmoed-de Vries; Lars Farde
Central 5-HT2A and D2 dopamine receptor occupancy after sublingual administration of ORG 5222 in healthy men.
Psychopharmacology 1997;131(4):339-45.
1997: Kim A Bergström; Christer Halldin; Håkan Hall; Camilla Lundkvist; N Ginovart; Carl-Gunnar Swahn; Lars Farde
In vitro and in vivo characterisation of nor-beta-CIT: a potential radioligand for visualisation of the serotonin transporter in the brain.
European journal of nuclear medicine 1997;24(6):596-601.
1997: Jyrki T Kuikka; KK Akerman; Jukka Hiltunen; Kim A Bergström; Pirkko Räsänen; Esko Vanninen; Christer Halldin; Jari Tiihonen
Striatal and extrastriatal imaging of dopamine D2 receptors in the living human brain with [123I]epidepride single-photon emission tomography.
European journal of nuclear medicine 1997;24(5):483-7.
1997: N Ginovart; Lars Farde; Christer Halldin; Carl-Gunnar Swahn
Effect of reserpine-induced depletion of synaptic dopamine on [11C]raclopride binding to D2-dopamine receptors in the monkey brain.
Synapse (New York, N.Y.) 1997;25(4):321-5.
1997: N Ginovart; Anders Lundin; Lars Farde; Christer Halldin; Lars Bäckman; Carl-Gunnar Swahn; Stefan Pauli; Göran C Sedvall
PET study of the pre- and post-synaptic dopaminergic markers for the neurodegenerative process in Huntington's disease.
Brain : a journal of neurology 1997;120 ( Pt 3)():503-14.
1997: Lars Farde; R J Mack; Svante Nyberg; Christer Halldin
D2 occupancy, extrapyramidal side effects and antipsychotic drug treatment: a pilot study with sertindole in healthy subjects.
International clinical psychopharmacology 1997;12 Suppl 1():S3-7.
1997: Håkan Hall; Camilla Lundkvist; Christer Halldin; Lars Farde; Victor W Pike; Julie A McCarron; A Fletcher; I A Cliffe; T Barf; Håkan V Wikström; Göran C Sedvall
Autoradiographic localization of 5-HT1A receptors in the post-mortem human brain using [3H]WAY-100635 and [11C]way-100635.
Brain research 1997;745(1-2):96-108.
1997: Svante Nyberg; Lars Farde; Christer Halldin
A PET study of 5-HT2 and D2 dopamine receptor occupancy induced by olanzapine in healthy subjects.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1997;16(1):1-7.
1996: Håkan Hall; Christer Halldin; D Dijkstra; H Wikström; Lawrence D Wise; Thomas A Pugsley; Pierre Sokoloff; Stefan Pauli; Lars Farde; Göran C Sedvall
Autoradiographic localisation of D3-dopamine receptors in the human brain using the selective D3-dopamine receptor agonist (+)-[3H]PD 128907.
Psychopharmacology 1996;128(3):240-7.
1996: S Nyberg; Lars Farde; Christer Halldin
Test-retest reliability of central [11C]raclopride binding at high D2 receptor occupancy. A PET study in haloperidol-treated patients.
Psychiatry research 1996;67(3):163-71.
1996: C Foged; Christer Halldin; Christian Loc'h; B Mazière; Per Karlsson; M Mazière; Carl-Gunnar Swahn; Lars Farde
11C- and 76Br-labelled NNC 22-0010, selective dopamine D1 receptor radioligands for PET.
Nuclear medicine and biology 1996;23(6):837-44.
1996: Christian Loc'h; Christer Halldin; Michel Bottlaender; Carl-Gunnar Swahn; Rosa Maria Moresco; M Mazière; Lars Farde; B Mazière
Preparation of [76Br]FLB 457 and [76Br]FLB 463 for examination of striatal and extrastriatal dopamine D-2 receptors with PET.
Nuclear medicine and biology 1996;23(6):813-9.
1996: Safiye Osman; Camilla Lundkvist; Victor W Pike; Christer Halldin; Julie A McCarron; Carl-Gunnar Swahn; N Ginovart; Sajinder K Luthra; Christopher J Bench; Paul M Grasby; H Wikström; T Barf; I A Cliffe; A Fletcher; Lars Farde
Characterization of the radioactive metabolites of the 5-HT1A receptor radioligand, [O-methyl-11C]WAY-100635, in monkey and human plasma by HPLC: comparison of the behaviour of an identified radioactive metabolite with parent radioligand in monkey using PET.
Nuclear medicine and biology 1996;23(5):627-34.
1996: Lars Farde; T Suhara; Christer Halldin; H Nybäck; Y Nakashima; Carl-Gunnar Swahn; Per Karlsson; N Ginovart; Frank P Bymaster; Harlan E Shannon; C Foged; PD Suzdak; Per Sauerberg
PET study of the M1-agonists [11C]xanomeline and [11C]butylthio-TZTP in monkey and man.
Dementia (Basel, Switzerland) 1996;7(4):187-95.
1996: Jyrki T Kuikka; Jukka Hiltunen; C Foged; Kim A Bergström; Christer Halldin; K Akerman; Jari Tiihonen; Lars Farde
Initial human studies with single-photon emission tomography using iodine-123 labelled 3-(5-cyclopropyl-1,2,4-oxadiazo-3-yl)- 7-iodo-5, 6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine (NNC 13-8241).
European journal of nuclear medicine 1996;23(7):798-803.
1996: Håkan Hall; Lars Farde; Christer Halldin; Y L Hurd; Stefan Pauli; Göran C Sedvall
Autoradiographic localization of extrastriatal D2-dopamine receptors in the human brain using [125I]epidepride.
Synapse (New York, N.Y.) 1996;23(2):115-23.
1996: Svante Nyberg; Y Nakashima; Anna-Lena Nordström; Christer Halldin; Lars Farde
Positron emission tomography of in-vivo binding characteristics of atypical antipsychotic drugs. Review of D2 and 5-HT2 receptor occupancy studies and clinical response.
The British journal of psychiatry. Supplement 1996;(29):40-4.
1996: Christer Halldin; Lars Farde; Camilla Lundkvist; N Ginovart; Y Nakashima; Per Karlsson; Carl-Gunnar Swahn
[11C]beta-CIT-FE, a radioligand for quantitation of the dopamine transporter in the living brain using positron emission tomography.
Synapse (New York, N.Y.) 1996;22(4):386-90.
1996: Kjell Någren; Christer Halldin; Carl-Gunnar Swahn; T Suhara; Lars Farde
[11C]metaraminol, a false neurotransmitter: preparation, metabolite studies and positron emission tomography examination in monkey.
Nuclear medicine and biology 1996;23(3):221-7.
1996: C Foged; Christer Halldin; Jukka Hiltunen; C Braestrup; C Thomsen; H C Hansen; T Suhara; Stefan Pauli; Carl-Gunnar Swahn; Per Karlsson; S Larsson; Lars Farde
Development of 123I-labelled NNC 13-8241 as a radioligand for SPECT visualization of benzodiazepine receptor binding.
Nuclear medicine and biology 1996;23(3):201-9.
1996: T Suhara; Lars Farde; Christer Halldin; K Någren; P Karlsson
Effects of cocaine on [11C]norepinephrine and [11C] beta-CIT uptake in the primate peripheral organs measured by PET.
Annals of nuclear medicine 1996;10(1):85-8.
1996: Camilla Lundkvist; Christer Halldin; N Ginovart; Svante Nyberg; Carl-Gunnar Swahn; A A Carr; F Brunner; Lars Farde
[11C]MDL 100907, a radioligland for selective imaging of 5-HT(2A) receptors with positron emission tomography.
Life sciences 1996;58(10):PL 187-92.
1995: Bernard Maziere; Christian Loc'h; L Müller; Christer Halldin
76Br-beta-CBT, a PET tracer for investigating dopamine neuronal uptake.
Nuclear medicine and biology 1995;22(8):993-7.
1995: Kim A Bergström; Christer Halldin; J T Kuikka; Carl-Gunnar Swahn; J Tiihonen; Jukka Hiltunen; E Länsimies; Lars Farde
The metabolite pattern of [123I]beta-CIT determined with a gradient HPLC method.
Nuclear medicine and biology 1995;22(8):971-6.
1995: Kjell Någren; Christer Halldin; L Müller; Carl-Gunnar Swahn; Pertti Lehikoinen
Comparison of [11C]methyl triflate and [11C]methyl iodide in the synthesis of PET radioligands such as [11C]beta-CIT and [11C]beta-CFT.
Nuclear medicine and biology 1995;22(8):965-79.
1995: Simon M Ametamey; Christer Halldin; C G Swahn; Håkan Hall; P August Schubiger; Lars Farde
Synthesis of nor-beta-CIT, beta-CIT and trimethylstannyl-beta-CT.
Nuclear medicine and biology 1995;22(8):959-64.
1995: Lars Farde; Christer Halldin; Kjell Någren; Per Karlsson; Carl-Gunnar Swahn; T Suhara
PET examination of the monkey heart with high specific radioactivity [11C]norepinephrine and [11C]metaraminol.
Nuclear medicine and biology 1995;22(8):1053-6.
1995: Carl-Gunnar Swahn; Christer Halldin; Kjell Någren; Lars Farde
An HPLC-method for determination of ligand metabolism during PET studies with [11C]metaraminol and [11C]norepinephrine.
Nuclear medicine and biology 1995;22(8):1045-8.
1995: Kjell Någren; Christer Halldin; Carl-Gunnar Swahn; K O Schoeps; O Langer; M Mitterhauser; I Zolle
Some new methods for the synthesis of cardiac neurotransmission PET radiotracers.
Nuclear medicine and biology 1995;22(8):1037-43.
1995: Svante Nyberg; Lars Farde; A Bartfai; Christer Halldin
Central D2 receptor occupancy and effects of zuclopenthixol acetate in humans.
International clinical psychopharmacology 1995;10(4):221-7.
1995: Per Karlsson; Göran C Sedvall; Christer Halldin; Carl-Gunnar Swahn; Lars Farde
Evaluation of SCH 39166 as PET ligand for central D1 dopamine receptor binding and occupancy in man.
Psychopharmacology 1995;121(3):300-8.
1995: Camilla Lundkvist; Christer Halldin; Carl-Gunnar Swahn; Håkan Hall; Per Karlsson; Y Nakashima; S Wang; R A Milius; J L Neumeyer; Lars Farde
[O-methyl-11C]beta-CIT-FP, a potential radioligand for quantitation of the dopamine transporter: preparation, autoradiography, metabolite studies, and positron emission tomography examinations.
Nuclear medicine and biology 1995;22(7):905-13.
1995: Anna-Lena Nordström; Lars Farde; Svante Nyberg; Per Karlsson; Christer Halldin; Göran C Sedvall
D1, D2, and 5-HT2 receptor occupancy in relation to clozapine serum concentration: a PET study of schizophrenic patients.
The American journal of psychiatry 1995;152(10):1444-9.
1995: Svante Nyberg; Anna-Lena Nordström; Christer Halldin; Lars Farde
Positron emission tomography studies on D2 dopamine receptor occupancy and plasma antipsychotic drug levels in man.
International clinical psychopharmacology 1995;10 Suppl 3():81-5.
1995: Anna-Lena Nordström; Lars Farde; L Eriksson; Christer Halldin
No elevated D2 dopamine receptors in neuroleptic-naive schizophrenic patients revealed by positron emission tomography and [11C]N-methylspiperone.
Psychiatry research 1995;61(2):67-83.
1995: L Müller; Håkan Hall; Christer Halldin; Lars Farde; R Hohlweg; P D Suzdak; E B Nielsen; C Foged
Synthesis and binding properties of [3H]NNC 12-0781, a new radioligand for the dopamine reuptake system.
Nuclear medicine and biology 1995;22(6):711-7.
1995: Christer Halldin; Lars Farde; Thomas Högberg; Nina Mohell; Håkan Hall; T Suhara; Per Karlsson; Y Nakashima; Carl-Gunnar Swahn
Carbon-11-FLB 457: a radioligand for extrastriatal D2 dopamine receptors.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(7):1275-81.
1995: Lars Farde; Håkan Hall; Stefan Pauli; Christer Halldin
Variability in D2-dopamine receptor density and affinity: a PET study with [11C]raclopride in man.
Synapse (New York, N.Y.) 1995;20(3):200-8.
1995: Stefan Brené; Håkan Hall; Nils Lindefors; Per Karlsson; Christer Halldin; Göran C Sedvall
Distribution of messenger RNAs for D1 dopamine receptors and DARPP-32 in striatum and cerebral cortex of the cynomolgus monkey: relationship to D1 dopamine receptors.
Neuroscience 1995;67(1):37-48.
1995: Svante Nyberg; M L Dahl; Christer Halldin
A PET study of D2 and 5-HT2 receptor occupancy induced by risperidone in poor metabolizers of debrisoquin and risperidone.
Psychopharmacology 1995;119(3):345-8.
1995: Per Karlsson; Lars Farde; Christer Halldin; Göran C Sedvall; L Ynddal; M Sloth-Nielsen
Oral administration of NNC 756--a placebo controlled PET study of D1-dopamine receptor occupancy and pharmacodynamics in man.
Psychopharmacology 1995;119(1):1-8.
1995: L Müller; Christer Halldin; C Foged; R Hohlweg
Synthesis of [18F]NNC 12-0817 and [18F]NNC 12-0818; two potential radioligands for the dopamine transporter.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1995;46(5):323-8.
1995: Kim A Bergström; Christer Halldin; Jyrki T Kuikka; Carl-Gunnar Swahn; Jari Tiihonen; Jukka Hiltunen; Esko Länsimies; Lars Farde
Lipophilic metabolite of [123I]beta-CIT in human plasma may obstruct quantitation of the dopamine transporter.
Synapse (New York, N.Y.) 1995;19(4):297-300.
1995: Håkan Hall; Christer Halldin; Svante Nyberg; Lars Farde; Göran C Sedvall
Effect of clozapine and risperidone on 5-HT2 and D2-dopamine receptor binding in the post-mortem human brain. An autoradiographic study.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1995;5(1):19-25.
1995: Svante Nyberg; Lars Farde; Christer Halldin; M L Dahl; L Bertilsson
D2 dopamine receptor occupancy during low-dose treatment with haloperidol decanoate.
The American journal of psychiatry 1995;152(2):173-8.
1995: Kjell Någren; L Müller; Christer Halldin; Carl-Gunnar Swahn; Pertti Lehikoinen
Improved synthesis of some commonly used PET radioligands by the use of [11C]methyl triflate.
Nuclear medicine and biology 1995;22(2):235-9.
1995: Lars Farde; Svante Nyberg; G Oxenstierna; Y Nakashima; Christer Halldin; B Ericsson
Positron emission tomography studies on D2 and 5-HT2 receptor binding in risperidone-treated schizophrenic patients.
Journal of clinical psychopharmacology 1995;15(1 Suppl 1):19S-23S.
1995: Göran C Sedvall; Stefan Pauli; Per Karlsson; Lars Farde; Anna-Lena Nordström; Svante Nyberg; Christer Halldin
PET imaging of neuroreceptors in schizophrenia.
European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology 1995;5 Suppl():25-30.
1995: Göran C Sedvall; Lars Farde; Håkan Hall; Christer Halldin; Per Karlsson; Anna-Lena Nordström; Svante Nyberg; Stefan Pauli
Utilization of radioligands in schizophrenia research.
Clinical neuroscience (New York, N.Y.) 1995;3(2):112-21.
1994: Håkan Hall; Göran C Sedvall; O Magnusson; J Kopp; Christer Halldin; Lars Farde
Distribution of D1- and D2-dopamine receptors, and dopamine and its metabolites in the human brain.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 1994;11(4):245-56.
1994: Lars Farde; Anna-Lena Nordström; Svante Nyberg; Christer Halldin; Göran C Sedvall
D1-, D2-, and 5-HT2-receptor occupancy in clozapine-treated patients.
The Journal of clinical psychiatry 1994;55 Suppl B():67-9.
1994: H Nybäck; Christer Halldin; A Ahlin; M Curvall; L Eriksson
PET studies of the uptake of (S)- and (R)-[11C]nicotine in the human brain: difficulties in visualizing specific receptor binding in vivo.
Psychopharmacology 1994;115(1-2):31-6.
1994: Christer Halldin; Thomas Högberg; Lars Farde
Fluorine-18-labelled NCQ 115, a selective dopamine D-2 receptor ligand. Preparation and positron emission tomography.
Nuclear medicine and biology 1994;21(4):627-31.
1994: G Blomqvist; R J Seitz; I Sjögren; Christer Halldin; Sharon Stone-Elander; L Widén; Olof Solin; Merja Haaparanta
Regional cerebral oxidative and total glucose consumption during rest and activation studied with positron emission tomography.
Acta physiologica Scandinavica 1994;151(1):29-43.
1994: Kjell Någren; K O Schoeps; Christer Halldin; Carl-Gunnar Swahn; Lars Farde
Selective synthesis of racemic 1-11C-labelled norepinephrine, octopamine, norphenylephrine and phenylethanolamine using [11C]nitromethane.
Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine 1994;45(4):515-21.
1994: Lars Farde; Christer Halldin; Kjell Någren; T Suhara; Per Karlsson; K O Schoeps; Carl-Gunnar Swahn; D Bone
Positron emission tomography shows high specific uptake of racemic carbon-11 labelled norepinephrine in the primate heart.
European journal of nuclear medicine 1994;21(4):345-7.
1994: Lars Farde; Christer Halldin; L Müller; T Suhara; Per Karlsson; Håkan Hall
PET study of [11C]beta-CIT binding to monoamine transporters in the monkey and human brain.
Synapse (New York, N.Y.) 1994;16(2):93-103.
1994: L Müller; Christer Halldin; C Foged; Per Karlsson; Håkan Hall; Carl-Gunnar Swahn; P D Suzdak; R Hohlweg; E B Nielsen; Lars Farde
Preparation of a potential positron emission tomographic radioligand for the dopamine transporter.
European journal of nuclear medicine 1994;21(2):131-7.
1994: Göran C Sedvall; Per Karlsson; Anders Lundin; Maria Anvret; T Suhara; Christer Halldin; Lars Farde
Dopamine D1 receptor number--a sensitive PET marker for early brain degeneration in Huntington's disease.
European archives of psychiatry and clinical neuroscience 1994;243(5):249-55.
1994: Lars Farde; Stefan Pauli; J E Litton; Christer Halldin; J Neiman; Göran C Sedvall
PET-determination of benzodiazepine receptor binding in studies on alcoholism.
EXS 1994;71():143-53.
1993: Christer Halldin; C Foged; Lars Farde; Per Karlsson; K Hansen; F Grønvald; Carl-Gunnar Swahn; Håkan Hall; Göran C Sedvall
[11C]NNC 687 and [11C]NNC 756, dopamine D-1 receptor ligands. Preparation, autoradiography and PET investigation in monkey.
Nuclear medicine and biology 1993;20(8):945-53.
1993: K O Schoeps; Christer Halldin; Kjell Någren; Carl-Gunnar Swahn; Per Karlsson; Håkan Hall; Lars Farde
Preparation of [1-11C]dopamine, [1-11C]p-tyramine and [1-11C]m-tyramine. Autoradiography and PET examination of [1-11C]dopamine in primates.
Nuclear medicine and biology 1993;20(5):669-78.
1993: Victor W Pike; Christer Halldin; C Crouzel; L Barré; David J Nutt; Safiye Osman; F Shah; D R Turton; S L Waters
Radioligands for PET studies of central benzodiazepine receptors and PK (peripheral benzodiazepine) binding sites--current status.
Nuclear medicine and biology 1993;20(4):503-25.
1993: L Müller; Christer Halldin; Lars Farde; Per Karlsson; Håkan Hall; Carl-Gunnar Swahn; J Neumeyer; Y Gao; R Milius
[11C] beta-CIT, a cocaine analogue. Preparation, autoradiography and preliminary PET investigations.
Nuclear medicine and biology 1993;20(3):249-55.
1993: J E Litton; J Neiman; Stefan Pauli; Lars Farde; T Hindmarsh; Christer Halldin; Göran C Sedvall
PET analysis of [11C]flumazenil binding to benzodiazepine receptors in chronic alcohol-dependent men and healthy controls.
Psychiatry research 1993;50(1):1-13.
1993: Håkan Hall; Christer Halldin; Göran C Sedvall
Binding of [3H]SCH 39166 to human post mortem brain tissue.
Pharmacology & toxicology 1993;72(3):152-8.
1993: Anna-Lena Nordström; Lars Farde; Frits-Axel Wiesel; K Forslund; Stefan Pauli; Christer Halldin; G Uppfeldt
Central D2-dopamine receptor occupancy in relation to antipsychotic drug effects: a double-blind PET study of schizophrenic patients.
Biological psychiatry 1993;33(4):227-35.
1993: Per Karlsson; Lars Farde; Christer Halldin; Carl-Gunnar Swahn; Göran C Sedvall; C Foged; Kristian Tage Hansen; B Skrumsager
PET examination of [11C]NNC 687 and [11C]NNC 756 as new radioligands for the D1-dopamine receptor.
Psychopharmacology 1993;113(2):149-56.
1993: Anna-Lena Nordström; Lars Farde; Christer Halldin
High 5-HT2 receptor occupancy in clozapine treated patients demonstrated by PET.
Psychopharmacology 1993;110(3):365-7.
1993: Svante Nyberg; Lars Farde; L Eriksson; Christer Halldin; B Eriksson
5-HT2 and D2 dopamine receptor occupancy in the living human brain. A PET study with risperidone.
Psychopharmacology 1993;110(3):265-72.
1992: Christer Halldin; Kjell Någren; Carl-Gunnar Swahn; B Långström; H Nybäck
(S)- and (R)-[11C]nicotine and the metabolite (R/S)-[11C]cotinine. Preparation, metabolite studies and in vivo distribution in the human brain using PET.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(8):871-80.
1992: Lars Farde; Anna-Lena Nordström; Frits-Axel Wiesel; Stefan Pauli; Christer Halldin; Göran C Sedvall
Positron emission tomographic analysis of central D1 and D2 dopamine receptor occupancy in patients treated with classical neuroleptics and clozapine. Relation to extrapyramidal side effects.
Archives of general psychiatry 1992;49(7):538-44.
1992: B Mazière; H H Coenen; Christer Halldin; K Någren; V W Pike
PET radioligands for dopamine receptors and re-uptake sites: chemistry and biochemistry.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1992;19(4):497-512.
1992: Håkan Hall; Lars Farde; Christer Halldin; Thomas Högberg; S Larsson; Göran C Sedvall
Imaging of dopamine receptors using PET and SPECT.
Neurochemistry international 1992;20 Suppl():329S-333S.
1992: Håkan Hall; Christer Halldin; Göran C Sedvall
Gpp(NH)p stimulates [3H]raclopride binding to homogenates from human putamen and accumbens.
Neuroscience letters 1992;136(1):79-82.
1992: Anna-Lena Nordström; Lars Farde; Christer Halldin
Time course of D2-dopamine receptor occupancy examined by PET after single oral doses of haloperidol.
Psychopharmacology 1992;106(4):433-8.
1992: C G Sedvall; Lars Farde; Håkan Hall; Christer Halldin; P Karlsson; S Brene; Nils Lindefors; H Persson; R E Chipkin; M Ehrlich
Ligand selection for PET studies of D1 dopamine receptors. Relationship between distribution of binding sites and mRNA for DAARPP32 in the human brain.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():466A-467A.
1992: Lars Farde; Anna-Lena Nordström; Christer Halldin; Frits-Axel Wiesel; Göran C Sedvall
PET studies of dopamine receptors in relation to antipsychotic drug treatment.
Clinical neuropharmacology 1992;15 Suppl 1 Pt A():468A-469A.
1992: Christer Halldin; Lars Farde; J E Litton; Håkan Hall; Göran C Sedvall
[11C]Ro 15-4513, a ligand for visualization of benzodiazepine receptor binding. Preparation, autoradiography and positron emission tomography.
Psychopharmacology 1992;108(1-2):16-22.
1992: Stefan Pauli; S Liljequist; Lars Farde; Carl-Gunnar Swahn; Christer Halldin; J E Litton; Göran C Sedvall
PET analysis of alcohol interaction with the brain disposition of [11C]flumazenil.
Psychopharmacology 1992;107(2-3):180-5.
1991: Frits-Axel Wiesel; G Blomqvist; Christer Halldin; I Sjögren; Lars Bjerkenstedt; Nikolaos Venizelos; L Hagenfeldt
The transport of tyrosine into the human brain as determined with L-[1-11C]tyrosine and PET.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(11):2043-9.
1991: Håkan Hall; Thomas Högberg; Christer Halldin; S Bengtsson; I Wedel
Synthesis and binding properties of the fluorinated substituted benzamide [3H]NCQ 115, a new selective dopamine D2 receptor ligand.
European journal of pharmacology 1991;201(1):1-10.
1991: S S Jossan; Per-Göran Gillberg; R d'Argy; Sten-Magnus Aquilonius; Bengt Långström; Christer Halldin; Lars Oreland
Quantitative localization of human brain monoamine oxidase B by large section autoradiography using L-[3H]deprenyl.
Brain research 1991;547(1):69-76.
1991: C Köhler; H Ericson; Thomas Högberg; Christer Halldin; V Chan-Palay
Dopamine D2 receptors in the rat, monkey and the post-mortem human hippocampus. An autoradiographic study using the novel D2-selective ligand 125I-NCQ 298.
Neuroscience letters 1991;125(1):12-4.
1991: A Persson; R d'Argy; Per-Göran Gillberg; Christer Halldin; J E Litton; Carl-Gunnar Swahn; Göran C Sedvall
Autoradiography with saturation experiments of 11C-Ro 15-1788 binding to human brain sections.
Journal of neuroscience methods 1991;36(1):53-61.
1991: Christer Halldin; Lars Farde; Thomas Högberg; Håkan Hall; P Ström; A Ohlberger; O Solin
A comparative PET-study of five carbon-11 or fluorine-18 labelled salicylamides. Preparation and in vitro dopamine D-2 receptor binding.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1991;18(8):871-81.
1991: Göran C Sedvall; Lars Farde; A Barnett; Håkan Hall; Christer Halldin
11C-SCH 39166, a selective ligand for visualization of dopamine-D1 receptor binding in the monkey brain using PET.
Psychopharmacology 1991;103(2):150-3.
1991: Håkan Hall; Thomas Högberg; Christer Halldin; C Köhler; P Ström; S B Ross; S A Larsson; Lars Farde
NCQ 298, a new selective iodinated salicylamide ligand for the labelling of dopamine D2 receptors.
Psychopharmacology 1991;103(1):6-18.
1991: K O Schoeps; S Ram; R Ehrenkaufer; Christer Halldin
Synthesis of [2-11C]glycine from [11C]nitromethane.
Acta radiologica. Supplementum 1991;376():95.
1991: J O Thorell; Sharon Stone-Elander; Christer Halldin; L Widén
Synthesis of [1-11C]-beta-hydroxybutyric acid.
Acta radiologica. Supplementum 1991;376():94.
1991: G Blomqvist; Sharon Stone-Elander; Christer Halldin; Per E Roland; C G Swahn; Merja Haaparanta; Olof Solin; M Lindqvist; L Widén
Cerebral glucose utilization measured by positron emission tomography. [1-11C]-D-glucose compared with [2-18F]-2-fluoro-2-deoxy-D-glucose.
Acta radiologica. Supplementum 1991;376():171-2.
1991: A Persson; R d'Argy; Per-Göran Gillberg; Christer Halldin; J L Litton; Carl-Gunnar Swahn; Göran C Sedvall
Autoradiography and saturation experiments with 11C-RO 15-1788 binding to human brain.
Acta radiologica. Supplementum 1991;376():169-70.
1991: Christer Halldin; Lars Farde; Håkan Hall; Thomas Högberg; G Printz; W Pulka; Göran C Sedvall; O Solin
Synthesis of five benzamide analogs. Comparison with positron emission tomography.
Acta radiologica. Supplementum 1991;376():121-2.
1991: Sharon Stone-Elander; Christer Halldin; B Långström; G Blomqvist; F Hamnqvist; G Printz; L Widén
Production method for [11C]-D-glucose labeled in carbon-1 for positron emission tomography of glucose metabolism.
Acta radiologica. Supplementum 1991;376():102-3.
1991: K O Schoeps; B Långström; Sharon Stone-Elander; Christer Halldin
Synthesis of [1-11C]D-glucose and [1-11C]D-mannose from on-line produced [11C]nitromethane.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(9):877-83.
1991: Sharon Stone-Elander; P Roland; E Schwenner; Christer Halldin; L Widén
Synthesis of [isopropyl-11C]nimodipine for in vivo studies of dihydropyridine binding in man using positron emission tomography.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(9):871-5.
1991: Christer Halldin; Lars Farde; A Barnett; Göran C Sedvall
Synthesis of carbon-11 labelled SCH 39166, a new selective dopamine D-1 receptor ligand, and preliminary PET investigations.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1991;42(5):451-5.
1990: Håkan Hall; I Wedel; Christer Halldin; J Kopp; Lars Farde
Comparison of the in vitro receptor binding properties of N-[3H]methylspiperone and [3H]raclopride to rat and human brain membranes.
Journal of neurochemistry 1990;55(6):2048-57.
1990: G Blomqvist; Sharon Stone-Elander; Christer Halldin; Per E Roland; L Widén; M Lindqvist; C G Swahn; B Långström; Frits-Axel Wiesel
Positron emission tomographic measurements of cerebral glucose utilization using [1-11C]D-glucose.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1990;10(4):467-83.
1990: Lars Farde; Frits-Axel Wiesel; Sharon Stone-Elander; Christer Halldin; Anna-Lena Nordström; Håkan Hall; Göran C Sedvall
D2 dopamine receptors in neuroleptic-naive schizophrenic patients. A positron emission tomography study with [11C]raclopride.
Archives of general psychiatry 1990;47(3):213-9.
1990: Christer Halldin; Lars Farde; Thomas Högberg; Håkan Hall; G Sedvall
Carbon-11 labelling of eticlopride in two different positions--a selective high-affinity ligand for the study of dopamine D-2 receptors using PET.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1990;41(7):669-74.
1990: G Blomqvist; Stefan Pauli; Lars Farde; L Eriksson; A Persson; Christer Halldin
Maps of receptor binding parameters in the human brain--a kinetic analysis of PET measurements.
European journal of nuclear medicine 1990;16(4-6):257-65.
1990: Thomas Högberg; P Ström; Håkan Hall; C Köhler; Christer Halldin; Lars Farde
Syntheses of [123I]-, [125I]- and unlabelled (S)-3-iodo-5,6-dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]salicylamide (NCQ 298), selective ligands for the study of dopamine D-2 receptors.
Acta pharmaceutica Nordica 1990;2(1):53-60.
1989: Lars Farde; L Eriksson; G Blomquist; Christer Halldin
Kinetic analysis of central [11C]raclopride binding to D2-dopamine receptors studied by PET--a comparison to the equilibrium analysis.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1989;9(5):696-708.
1989: S Stone-Elander; P Roland; Christer Halldin; M Hassan; R Seitz
Synthesis of [11C]sodium thiocyanate for in vivo studies of anion kinetics using positron emission tomography (PET).
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1989;16(7):741-6.
1989: H Nybäck; agneta nordberg; B Långström; Christer Halldin; P Hartvig; A Ahlin; C G Swahn; G Sedvall
Attempts to visualize nicotinic receptors in the brain of monkey and man by positron emission tomography.
Progress in brain research 1989;79():313-9.
1989: Frits-Axel Wiesel; Lars Farde; Christer Halldin
Clinical melperone treatment blocks D2-dopamine receptors in the human brain as determined by PET.
Acta psychiatrica Scandinavica. Supplementum 1989;352():30-4.
1989: Christer Halldin; P Bjurling; C G Stålnacke; S S Jossan; L Oreland; Bengt Långström
11C-labelling of dimethylphenethylamine in two different positions and biodistribution studies.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1989;40(7):557-60.
1989: K O Schoeps; Sharon Stone-Elander; Christer Halldin
On-line synthesis of [11C]nitroalkanes.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1989;40(3):261-2.
1989: S S Jossan; R d'Argy; Per-Göran Gillberg; Sten-Magnus Aquilonius; Bengt Långström; Christer Halldin; P Bjurling; C G Stålnacke; J Fowler; R MacGregor
Localization of monoamine oxidase B in human brain by autoradiographical use of 11C-labelled L-deprenyl.
Journal of neural transmission 1989;77(1):55-64.
1988: Lars Farde; Stefan Pauli; Håkan Hall; L Eriksson; Christer Halldin; Thomas Högberg; L Nilsson; I Sjögren; Sharon Stone-Elander
Stereoselective binding of 11C-raclopride in living human brain--a search for extrastriatal central D2-dopamine receptors by PET.
Psychopharmacology 1988;94(4):471-8.
1988: R d'Argy; R Paul; L Frankenberg; C G Stålnacke; Hans Lundqvist; L Kangas; Christer Halldin; Kjell Någren; D Roeda; Merja Haaparanta
Comparative double-tracer whole-body autoradiography: uptake of 11C-, 18F- and 3H-labeled compounds in rat tumors.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1988;15(5):577-85.
1988: Lars Farde; Frits-Axel Wiesel; Christer Halldin; Göran C Sedvall
Central D2-dopamine receptor occupancy in schizophrenic patients treated with antipsychotic drugs.
Archives of general psychiatry 1988;45(1):71-6.
1988: Christer Halldin; Sharon Stone-Elander; J O Thorell; A Persson; G Sedvall
11C-labelling of Ro 15-1788 in two different positions, and also 11C-labelling of its main metabolite Ro 15-3890, for PET studies of benzodiazepine receptors.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1988;39(9):993-7.
1987: C D Arnett; Joanna S Fowler; R R MacGregor; David Schlyer; AP Wolf; B Långström; Christer Halldin
Turnover of brain monoamine oxidase measured in vivo by positron emission tomography using L-[11C]deprenyl.
Journal of neurochemistry 1987;49(2):522-7.
1987: Lars Farde; F A Wiesel; Håkan Hall; Christer Halldin; S Stone-Elander; G Sedvall
No D2 receptor increase in PET study of schizophrenia.
Archives of general psychiatry 1987;44(7):671-2.
1987: Bengt Långström; G Antoni; P Gullberg; Christer Halldin; P Malmborg; K Någren; A Rimland; H Svärd
Synthesis of L- and D-[methyl-11C]methionine.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1987;28(6):1037-40.
1987: Christer Halldin; K O Schoeps; Sharon Stone-Elander; F A Wiesel
The Bücherer-Strecker synthesis of D- and L-(1-11C)tyrosine and the in vivo study of L-(1-11C)tyrosine in human brain using positron emission tomography.
European journal of nuclear medicine 1987;13(6):288-91.
1987: Yasuyoshi Watanabe; Bengt Långström; C G Stålnacke; P Gullberg; H Svärd; Christer Halldin; O Hayaishi
Synthesis of 11C-labeled prostaglandins and positron emission tomography studies using the rhesus monkey.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17B():943-5.
1987: Lars Farde; Christer Halldin; S Stone-Elander; G Sedvall
PET analysis of human dopamine receptor subtypes using 11C-SCH 23390 and 11C-raclopride.
Psychopharmacology 1987;92(3):278-84.
1986: Joanna S Fowler; C D Arnett; AP Wolf; Chyng-Yann Shiue; R R MacGregor; Christer Halldin; B Långström; Henry N Wagner
A direct comparison of the brain uptake and plasma clearance of N-[11C]methylspiroperidol and [18F]N-methylspiroperidol in baboon using PET.
International journal of radiation applications and instrumentation. Part B, Nuclear medicine and biology 1986;13(3):281-4.
1986: Per Hartvig; S A Eckernäs; Leif H Lindström; B Ekblom; U Bondesson; Hans Lundqvist; Christer Halldin; K Någren; Bengt Långström
Receptor binding of N-(methyl-11C) clozapine in the brain of rhesus monkey studied by positron emission tomography (PET).
Psychopharmacology 1986;89(2):248-52.
1986: Christer Halldin; Sharon Stone-Elander; Lars Farde; E Ehrin; K J Fasth; B Långström; Göran C Sedvall
Preparation of 11C-labelled SCH 23390 for the in vivo study of dopamine D-1 receptors using positron emission tomography.
International journal of radiation applications and instrumentation. Part A, Applied radiation and isotopes 1986;37(10):1039-43.
1986: G Sedvall; Lars Farde; S Stone-Elander; Christer Halldin
Dopamine D1-receptor binding in the living human brain.
Advances in experimental medicine and biology 1986;204():119-24.
1986: M Bergström; M Mosskin; K Ericson; E Ehrin; J O Thorell; Hans von Holst; G Norén; A Persson; Christer Halldin; Sharon Stone-Elander
Peripheral benzodiazepine binding sites in human gliomas evaluated with positron emission tomography.
Acta radiologica. Supplementum 1986;369():409-11.
1985: R R MacGregor; Christer Halldin; Joanna S Fowler; A P Wolf; C D Arnett; B Langström; D Alexoff
Selective, irreversible in vivo binding of [11C]clorgyline and [11C]-L-deprenyl in mice: potential for measurement of functional monoamine oxidase activity in brain using positron emission tomography.
Biochemical pharmacology 1985;34(17):3207-10.
1985: Anders Lilja; K Bergström; P Hartvig; B Spännare; Christer Halldin; Hans Lundqvist; B Långstrom
Dynamic study of supratentorial gliomas with L-methyl-11C-methionine and positron emission tomography.
AJNR. American journal of neuroradiology 1985;6(4):505-14.
1985: C G Stålnacke; S Sundell-Bergman; Christer Halldin; B Långström
Radiotoxicity of 11C-methionine measured by the accumulation of DNA strand breaks in mammalian cells.
European journal of nuclear medicine 1985;11(5):166-70.
1984: Lars Berglund; Christer Halldin; Anders Lilja; B S Lindberg; Hans Lundqvist; Bengt Långström; P Malmborg; K Någren; C G Stålnacke
11C-methionine kinetics in pregnant rhesus monkeys studied by positron emission tomography: a new approach to feto-maternal metabolism.
Acta obstetricia et gynecologica Scandinavica 1984;63(7):641-5.
1983: M Bergström; V P Collins; E Ehrin; K Ericson; L Eriksson; T Greitz; Christer Halldin; Hans von Holst; B Långström; A Lilja
Discrepancies in brain tumor extent as shown by computed tomography and positron emission tomography using [68Ga]EDTA, [11C]glucose, and [11C]methionine.
Journal of computer assisted tomography 1983;7(6):1062-6.