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Peter Halling

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Phenomena

Chemicals & Drugs

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Candida

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Co-Publications
Name
10
Ulijn, Rein
9
Moore, Barry
6
Flitsch, Sabine
5
Partridge, Johann
4
Ganesan, Ashok
4
Erbeldinger, M
4
Janssen, Anja
3
Kelly, Sharon
3
Fontes, Nuno
3
Barreiros, Susana
3
Price, Nicholas
3
Ni, X
2
McConnell, Gail
2
De Martin, Luigi
2
Gardossi, Lucia

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Publications

TOP 3
Ganesan Ashok; Moore Barry D; Kelly Sharon M; Price Nicholas C; Rolinski Olaf J; Birch David J S; Dunkin Ian R; Halling Peter J
Optical spectroscopic methods for probing the conformational stability of immobilised enzymes.
Halling Peter J
Estimation of flattening coefficient for absorption and circular dichroism using simulation.
Deere Joseph; De Oliveira Rui F; Tomaszewski Bartlomiej; Millar Sarah; Lalaouni Antonia; Solares Laura F; Flitsch Sabine L; Halling Peter J
Kinetics of enzyme attack on substrates covalently attached to solid surfaces: influence of spacer chain length, immobilized substrate surface concentration and surface charge.

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All Publications

2009: Ganesan Ashok; Moore Barry D; Kelly Sharon M; Price Nicholas C; Rolinski Olaf J; Birch David J S; Dunkin Ian R; Halling Peter J
Optical spectroscopic methods for probing the conformational stability of immobilised enzymes.
Chemphyschem : a European journal of chemical physics and physical chemistry 2009;10(9-10):1492-9.
2009: Halling Peter J
Estimation of flattening coefficient for absorption and circular dichroism using simulation.
Analytical biochemistry 2009;387(1):76-81.
2008: Deere Joseph; De Oliveira Rui F; Tomaszewski Bartlomiej; Millar Sarah; Lalaouni Antonia; Solares Laura F; Flitsch Sabine L; Halling Peter J
Kinetics of enzyme attack on substrates covalently attached to solid surfaces: influence of spacer chain length, immobilized substrate surface concentration and surface charge.
Langmuir : the ACS journal of surfaces and colloids 2008;24(20):11762-9.
2006: Petry Inga; Ganesan Ashok; Pitt Andrew; Moore Barry D; Halling Peter J
Proteomic methods applied to the analysis of immobilized biocatalysts.
Biotechnology and bioengineering 2006;95(5):984-91.
2006: Fermeglia Maurizio; Braiuca Paolo; Gardossi Lucia; Pricl Sabrina; Halling Peter J
In silico prediction of medium effects on esterification equilibrium using the COSMO-RS method.
Biotechnology progress 2006;22(4):1146-52.
2006: Ganesan Ashok; Price Nicholas C; Kelly Sharon M; Petry Inga; Moore Barry D; Halling Peter J
Circular dichroism studies of subtilisin Carlsberg immobilised on micron sized silica particles.
Biochimica et biophysica acta 2006;1764(6):1119-25.
2006: Halling P J
Understanding enzyme action at solid surfaces.
Biochemical Society transactions 2006;34(Pt 2):309-11.
2006: Castillo Betzaida; Bansal Vibha; Ganesan Ashok; Halling Peter; Secundo Francesco; Ferrer Amaris; Griebenow Kai; Barletta Gabriel
On the activity loss of hydrolases in organic solvents: II. a mechanistic study of subtilisin Carlsberg.
BMC biotechnology 2006;6():51.
2005: Halling Peter J; Ulijn Rein V; Flitsch Sabine L
Understanding enzyme action on immobilised substrates.
Current opinion in biotechnology 2005;16(4):385-92.
2004: Halling Peter J
What can we learn by studying enzymes in non-aqueous media?
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2004;359(1448):1287-96; discussion 1296-7, 1323-8.
2003: Bosma Annie Y; Ulijn Rein V; McConnell Gail; Girkin John; Halling Peter J; Flitsch Sabine L
Using two photon microscopy to quantify enzymatic reaction rates on polymer beads.
Chemical communications (Cambridge, England) 2003;(22):2790-1.
2003: Halling Peter J; Wilson Stephen K; Jacobs Ralf; McKee Sean; Coles Christopher W
Modeling the kinetics of enzymic reactions in mainly solid reaction mixtures.
Biotechnology progress 2003;19(4):1228-37.
2003: Fontes Nuno; Harper Neil; Halling Peter J; Barreiros Susana
Salt hydrates for in situ water activity control have acid-base effects on enzymes in nonaqueous media.
Biotechnology and bioengineering 2003;82(7):802-8.
2003: Ulijn Rein V; Brazendale Ian; Margetts Graham; Flitsch Sabine L; McConnell Gail; Girkin John; Halling Peter J
Two-photon microscopy to spatially resolve and quantify fluorophores in single-bead chemistry.
Journal of combinatorial chemistry 2003;5(3):215-7.
2003: Ulijn Rein V; Bisek Nicola; Halling Peter J; Flitsch Sabine L
Understanding protease catalysed solid phase peptide synthesis.
Organic & biomolecular chemistry 2003;1(8):1277-81.
2002: Ulijn Rein V; De Martin Luigi; Gardossi Lucia; Janssen Anja E M; Moore Barry D; Halling Peter J
Solvent selection for solid-to-solid synthesis.
Biotechnology and bioengineering 2002;80(5):509-15.
2002: Amorim Fernandes João F; Halling Peter J
Operational stability of high initial activity protease catalysts in organic solvents.
Biotechnology progress 2002;18(6):1455-7.
2002: Ulijn Rein V; Janssen Anja E M; Moore Barry D; Halling Peter J; Kelly Sharon M; Price Nicholas C
Reversible acetonitrile-induced inactivation/activation of thermolysin.
Chembiochem : a European journal of chemical biology 2002;3(11):1112-6.
2002: Ulijn R V; De Martin L; Halling P J; Moore B D; Janssen A E M
Enzymatic synthesis of beta-lactam antibiotics via direct condensation.
Journal of biotechnology 2002;99(3):215-22.
2002: Ulijn Rein V; Baragaña Beatriz; Halling Peter J; Flitsch Sabine L
Protease-catalyzed peptide synthesis on solid support.
Journal of the American Chemical Society 2002;124(37):10988-9.
2002: Flores Maria Victoria; Naraghi Kaynoush; Engasser Jean-Marc; Halling Peter J
Influence of glucose solubility and dissolution rate on the kinetics of lipase catalyzed synthesis of glucose laurate in 2-methyl 2-butanol.
Biotechnology and bioengineering 2002;78(7):815-21.
2002: Flores Maria Victoria; Halling Peter J
Full model for reversible kinetics of lipase-catalyzed sugar-ester synthesis in 2-methyl 2-butanol.
Biotechnology and bioengineering 2002;78(7):795-801.
2002: Fontes Nuno; Partridge Johann; Halling Peter J; Barreiros Susana
Zeolite molecular sieves have dramatic acid-base effects on enzymes in nonaqueous media.
Biotechnology and bioengineering 2002;77(3):296-305.
2001: van den Heuvel R H; Partridge J; Laane C; Halling P J; van Berkel W J
Tuning of the product spectrum of vanillyl-alcohol oxidase by medium engineering.
FEBS letters 2001;503(2-3):213-6.
2001: Ulijn R V; Janssen A E; Moore B D; Halling P J
Predicting when precipitation-driven synthesis is feasible: application to biocatalysis.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(10):2089-98.
2001: Fontes N; Almeida M C; Garcia S; Peres C; Partridge J; Halling P J; Barreiros S
Supercritical fluids are superior media for catalysis by cross-linked enzyme microcrystals of subtilisin Carlsberg.
Biotechnology progress 2001;17(2):355-8.
2001: Erbeldinger M; Ni X; Halling P J
Kinetics of enzymatic solid-to-solid peptide synthesis: synthesis of Z-aspartame and control of acid-base conditions by using inorganic salts.
Biotechnology and bioengineering 2001;72(1):69-76.
2000: Ulijn R V; Erbeldinger M; Halling P J
Comparison of methods for thermolysin-catalyzed peptide synthesis including a novel more active catalyst.
Biotechnology and bioengineering 2000;69(6):633-8.
2000: Halling P J
Biocatalysis in low-water media: understanding effects of reaction conditions.
Current opinion in chemical biology 2000;4(1):74-80.
2000: Ross A C; Bell G; Halling P J
Effect of pH on rate of interfacial inactivation of serine proteases in aqueous-organic systems.
Biotechnology and bioengineering 2000;67(4):498-503.
1999: Erbeldinger M; Ni X; Halling P J
Kinetics of enzymatic solid-to-solid peptide synthesis: intersubstrate compound, substrate ratio, and mixing effects.
Biotechnology and bioengineering 1999;63(3):316-21.
1999: Zacharis E; Halling P J; Rees D G
Volatile buffers can override the "pH memory" of subtilisin catalysis in organic media.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(4):1201-5.
1998: Erbeldinger M; Ni X; Halling P J
Effect of water and enzyme concentration on thermolysin-catalyzed solid-to-solid peptide synthesis.
Biotechnology and bioengineering 1998;59(1):68-72.
1998: Partridge J; Dennison P R; Moore B D; Halling P J
Activity and mobility of subtilisin in low water organic media: hydration is more important than solvent dielectric.
Biochimica et biophysica acta 1998;1386(1):79-89.
1997: Zacharis E; Omar I C; Partridge J; Robb D A; Halling P J
Selection of salt hydrate pairs for use in water control in enzyme catalysis in organic solvents.
Biotechnology and bioengineering 1997;55(2):367-74.
1997: Halling P J
Predicting the behaviour of lipases in low-water media.
Biochemical Society transactions 1997;25(1):170-4.
1996: Janssen A E; Vaidya A M; Halling P J
Substrate specificity and kinetics of Candida rugosa lipase in organic media.
Annals of the New York Academy of Sciences 1996;799():257-61.
1996: Janssen A E; Vaidya A M; Halling P J
Substrate specificity and kinetics of Candida rugosa lipase in organic media.
Enzyme and microbial technology 1996;18(5):340-6.
1996: Rosell C M; Vaidya A M; Halling P J
Continuous in situ water activity control for organic phase biocatalysis in a packed bed hollow fiber reactor.
Biotechnology and bioengineering 1996;49(3):284-9.
1995: Rosell C M; Vaidya A M; Halling P J
Prediction of denaturing tendency of organic solvents in mixtures with water by measurement of naphthalene solubility.
Biochimica et biophysica acta 1995;1252(1):158-64.
1994: Valivety R H; Halling P J; Peilow A D; Macrae A R
Relationship between water activity and catalytic activity of lipases in organic media. Effects of supports, loading and enzyme preparation.
European journal of biochemistry / FEBS 1994;222(2):461-6.
1994: Blackwood A D; Curran L J; Moore B D; Halling P J
'Organic phase buffers' control biocatalyst activity independent of initial aqueous pH.
Biochimica et biophysica acta 1994;1206(2):161-5.
1994: Halling P J
Thermodynamic predictions for biocatalysis in nonconventional media: theory, tests, and recommendations for experimental design and analysis.
Enzyme and microbial technology 1994;16(3):178-206.
1992: Blanco R M; Rakels J L; Guisán J M; Halling P J
Effect of thermodynamic water activity on amino-acid ester synthesis catalyzed by agarose-chymotrypsin in 3-pentanone.
Biochimica et biophysica acta 1992;1156(1):67-70.
1992: Valivety R H; Halling P J; Peilow A D; Macrae A R
Lipases from different sources vary widely in dependence of catalytic activity on water activity.
Biochimica et biophysica acta 1992;1122(2):143-6.
1992: Valivety R H; Halling P J; Macrae A R
Rhizomucor miehei lipase remains highly active at water activity below 0.0001.
FEBS letters 1992;301(3):258-60.
1992: Valivety R H; Halling P J; Macrae A R
Reaction rate with suspended lipase catalyst shows similar dependence on water activity in different organic solvents.
Biochimica et biophysica acta 1992;1118(3):218-22.
1991: Kuhl P; Halling P J
Salt hydrates buffer water activity during chymotrypsin-catalysed peptide synthesis.
Biochimica et biophysica acta 1991;1078(3):326-8.
1991: Halling P J
Effect of thermodynamic water activity on protease-catalyzed peptide synthesis in mainly organic media.
Biomedica biochimica acta 1991;50(10-11):S61-6.
1990: Cassells J M; Halling P J
Protease-catalysed peptide synthesis in aqueous-organic two-phase systems: reactant precipitation and interfacial inactivation.
Enzyme and microbial technology 1990;12(10):755-9.
1990: Halling P J
High-affinity binding of water by proteins is similar in air and in organic solvents.
Biochimica et biophysica acta 1990;1040(2):225-8.
1990: Zhang J X; Halling P J
pH and buffering in the bicinchoninic acid (4,4'-dicarboxy-2,2'-biquinoline) protein assay.
Analytical biochemistry 1990;188(1):9-10.
1989: Halling P J
Lipase-catalysed reactions in low-water organic media: effects of water activity and chemical modification.
Biochemical Society transactions 1989;17(6):1142-5.
1987: Halling P J
Biocatalysis in multi-phase reaction mixtures containing organic liquids.
Biotechnology advances 1987;5(1):47-84.

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