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Mitchell Halperin

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Kamel S Kamel; Mitchell L Halperin
Managing overly rapid correction of chronic hyponatremia: an ounce of prevention or a pound of cure?
Surinder Cheema-Dhadli; Chee Keong Chong; Mohammad Alazmi; Kamel S Kamel; Mitchell L Halperin
Is there escape from renal actions of vasopressin in rats with a hyponatremia for greater than 48 hours?
Surinder Cheema-Dhadli; Chee Keong Chong; Namhee Kim; Kamel S Kamel; Mitchell L Halperin
Importance of Residual Water Permeability on the Excretion of Water during Water Diuresis in Rats.

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All Publications

2010: Kamel S Kamel; Mitchell L Halperin
Managing overly rapid correction of chronic hyponatremia: an ounce of prevention or a pound of cure?
Journal of the American Society of Nephrology : JASN 2010;21(12):2015-6.
2010: Surinder Cheema-Dhadli; Chee Keong Chong; Mohammad Alazmi; Kamel S Kamel; Mitchell L Halperin
Is there escape from renal actions of vasopressin in rats with a hyponatremia for greater than 48 hours?
Electrolyte & blood pressure : E & BP 2010;8(1):10-7.
2010: Surinder Cheema-Dhadli; Chee Keong Chong; Namhee Kim; Kamel S Kamel; Mitchell L Halperin
Importance of Residual Water Permeability on the Excretion of Water during Water Diuresis in Rats.
Electrolyte & blood pressure : E & BP 2010;8(1):1-9.
2010: Mitchell L Halperin; Kamel S Kamel
Some observations on the clinical approach to metabolic acidosis.
Journal of the American Society of Nephrology : JASN 2010;21(6):894-7.
2010: Mitchell L Halperin; Man S Oh; Kamel S Kamel
Integrating effects of aquaporins, vasopressin, distal delivery of filtrate and residual water permeability on the magnitude of water diuresis.
Nephron. Physiology 2010;114(1):p11-7.
2008: Ana P C P Carlotti; Desmond Bohn; A K Matsuno; D M Pasti; Manjula Gowrishankar; Mitchell L Halperin
Indicators of lean body mass catabolism: emphasis on the creatinine excretion rate.
QJM : monthly journal of the Association of Physicians 2008;101(3):197-205.
2007: Manjula Gowrishankar; Ana P C P Carlotti; C St George-Hyslop; Desmond Bohn; Kamel S Kamel; Mogamat Razeen Davids; Mitchell L Halperin
Uncovering the basis of a severe degree of acidemia in a patient with diabetic ketoacidosis.
QJM : monthly journal of the Association of Physicians 2007;100(11):721-35.
2007: Manjula Gowrishankar; Kamel S Kamel; Mitchell L Halperin
A brain protein centered view of H+ buffering.
Journal of the American Society of Nephrology : JASN 2007;18(8):2278-80.
2007: Ewout J Hoorn; Ana P C P Carlotti; Leila A A Costa; Beth MacMahon; Gareth Bohn; Robert Zietse; Mitchell L Halperin; Desmond Bohn
Preventing a drop in effective plasma osmolality to minimize the likelihood of cerebral edema during treatment of children with diabetic ketoacidosis.
The Journal of pediatrics 2007;150(5):467-73.
2007: Ana P C P Carlotti; Desmond Bohn; Kamel S Kamel; Mitchell L Halperin
Minimizing the risk of developing cerebral edema during therapy for diabetic ketoacidosis.
Critical care medicine 2007;35(5):1450; author reply 1450-1.
2007: Ana P C P Carlotti; Desmond Bohn; N Jankiewicz; Kamel S Kamel; Mogamat Razeen Davids; Mitchell L Halperin
A hyperglycaemic hyperosmolar state in a young child: diagnostic insights from a quantitative analysis.
QJM : monthly journal of the Association of Physicians 2007;100(2):125-37.
2007: Kamel S Kamel; Mohammad A Shafiee; Surinder Cheema-Dhadli; Mitchell L Halperin
Studies to identify the basis for an alkaline urine pH in patients with calcium hydrogen phosphate kidney stones.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2007;22(2):424-31.
2007: Shih-Hua Lin; Mitchell L Halperin
Hypokalemia: a practical approach to diagnosis and its genetic basis.
Current medicinal chemistry 2007;14(14):1551-65.
2007: Mitchell L Halperin; Kamel S Kamel
A new look at an old problem: therapy of chronic hyponatremia.
Nature clinical practice. Nephrology 2007;3(1):2-3.
2006: Mitchell L Halperin; Surinder Cheema-Dhadli; Kamel S Kamel
Physiology of acid-base balance: links with kidney stone prevention.
Seminars in nephrology 2006;26(6):441-6.
2006: Mitchell L Halperin; Surinder Cheema-Dhadli; Shih-Hua Lin; Kamel S Kamel
Properties permitting the renal cortex to be the oxygen sensor for the release of erythropoietin: clinical implications.
Clinical journal of the American Society of Nephrology : CJASN 2006;1(5):1049-53.
2006: Mitchell L Halperin; Caterina Maccari; Kamel S Kamel; Ana P C P Carlotti; Desmond Bohn
Strategies to diminish the danger of cerebral edema in a pediatric patient presenting with diabetic ketoacidosis.
Pediatric diabetes 2006;7(4):191-5.
2006: C Maccari; Kamel S Kamel; Mogamat Razeen Davids; Mitchell L Halperin
The patient with a severe degree of metabolic acidosis: a deductive analysis.
QJM : monthly journal of the Association of Physicians 2006;99(7):475-85.
2006: Mitchell L Halperin; Surinder Cheema-Dhadli; Shih-Hua Lin; Kamel S Kamel
Control of potassium excretion: a Paleolithic perspective.
Current opinion in nephrology and hypertension 2006;15(4):430-6.
2006: Surinder Cheema-Dhadli; Shih-Hua Lin; Chee Keong-Chong; Kamel S Kamel; Mitchell L Halperin
Requirements for a high rate of potassium excretion in rats consuming a low electrolyte diet.
The Journal of physiology 2006;572(Pt 2):493-501.
2006: Kamel S Kamel; Mitchell L Halperin
An improved approach to the patient with metabolic acidosis: a need for four amendments.
Journal of nephrology 2006;19 Suppl 9():S76-85.
2006: M Alazami; S-H Lin; C-J Cheng; Mogamat Razeen Davids; Mitchell L Halperin
Unusual causes of hypokalaemia and paralysis.
QJM : monthly journal of the Association of Physicians 2006;99(3):181-92.
2005: Desmond Bohn; Mogamat Razeen Davids; O Friedman; Mitchell L Halperin
Acute and fatal hyponatraemia after resection of a craniopharyngioma: a preventable tragedy.
QJM : monthly journal of the Association of Physicians 2005;98(9):691-703.
2005: Ewout J Hoorn; Mitchell L Halperin; Robert Zietse
Diagnostic approach to a patient with hyponatraemia: traditional versus physiology-based options.
QJM : monthly journal of the Association of Physicians 2005;98(7):529-40.
2005: Mohammad A Shafiee; Andre F Charest; Surinder Cheema-Dhadli; Daniel N Glick; Olga Napolova; Jamshid Roozbeh; Elena Semenova; Asheer Sharman; Mitchell L Halperin
Defining conditions that lead to the retention of water: the importance of the arterial sodium concentration.
Kidney international 2005;67(2):613-21.
2005: Kamel S Kamel; Surinder Cheema-Dhadli; Mohammad A Shafiee; Mogamat Razeen Davids; Mitchell L Halperin
Recurrent uric acid stones.
QJM : monthly journal of the Association of Physicians 2005;98(1):57-68.
2004: Nadia Zalunardo; Mathieu Lemaire; Mogamat Razeen Davids; Mitchell L Halperin
Acidosis in a patient with cholera: a need to redefine concepts.
QJM : monthly journal of the Association of Physicians 2004;97(10):681-96.
2004: Shih-Hua Lin; Yuh-Feng Lin; Dung-Tsa Chen; Pauling Chu; Chin-Wang Hsu; Mitchell L Halperin
Laboratory tests to determine the cause of hypokalemia and paralysis.
Archives of internal medicine 2004;164(14):1561-6.
2004: Mogamat Razeen Davids; A S Segal; H Brunengraber; Mitchell L Halperin
An unusual cause for ketoacidosis.
QJM : monthly journal of the Association of Physicians 2004;97(6):365-76.
2004: Kamel S Kamel; Surinder Cheema-Dhadli; Mohammad A Shafiee; Mitchell L Halperin
Dogmas and controversies in the handling of nitrogenous wastes: excretion of nitrogenous wastes in human subjects.
The Journal of experimental biology 2004;207(Pt 12):1985-91.
2004: Ewout J Hoorn; Denis F Geary; Maryanne Robb; Mitchell L Halperin; Desmond Bohn
Acute hyponatremia related to intravenous fluid administration in hospitalized children: an observational study.
Pediatrics 2004;113(5):1279-84.
2004: M Luthra; Mogamat Razeen Davids; Mohammad A Shafiee; Mitchell L Halperin
Anorexia nervosa and chronic renal insufficiency: a prescription for disaster.
QJM : monthly journal of the Association of Physicians 2004;97(3):167-78.
2004: Shih-Hua Lin; Nai-Lin Cheng; Yu-Juei Hsu; Mitchell L Halperin
Intrafamilial phenotype variability in patients with Gitelman syndrome having the same mutations in their thiazide-sensitive sodium/chloride cotransporter.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2004;43(2):304-12.
2003: Shih-Hua Lin; Yu-Juei Hsu; Jainn-Shiun Chiu; S-J Chu; Mogamat Razeen Davids; Mitchell L Halperin
Osmotic demyelination syndrome: a potentially avoidable disaster.
QJM : monthly journal of the Association of Physicians 2003;96(12):935-47.
2003: Olga Napolova; Stacey Urbach; Mogamat Razeen Davids; Mitchell L Halperin
Assessing the degree of extracellular fluid volume contraction in a patient with a severe degree of hyperglycaemia.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2003;18(12):2674-7.
2003: Mohammad A Shafiee; Desmond Bohn; Ewout J Hoorn; Mitchell L Halperin
How to select optimal maintenance intravenous fluid therapy.
QJM : monthly journal of the Association of Physicians 2003;96(8):601-10.
2003: Yeouda Edoute; Mogamat Razeen Davids; C Johnston; Mitchell L Halperin
An integrative physiological approach to polyuria and hyponatraemia: a 'double-take' on the diagnosis and therapy in a patient with schizophrenia.
QJM : monthly journal of the Association of Physicians 2003;96(7):531-40.
2003: Shih-Hua Lin; Sung-Sen Yang; Tom Chau; Mitchell L Halperin
An unusual cause of hypokalemic paralysis: chronic licorice ingestion.
The American journal of the medical sciences 2003;325(3):153-6.
2003: Shih-Hua Lin; Mogamat Razeen Davids; Mitchell L Halperin
Hypokalaemia and paralysis.
QJM : monthly journal of the Association of Physicians 2003;96(2):161-9.
2003: Ana P C P Carlotti; Desmond Bohn; Mitchell L Halperin
Importance of timing of risk factors for cerebral oedema during therapy for diabetic ketoacidosis.
Archives of disease in childhood 2003;88(2):170-3.
2002: Sheila Singh; Desmond Bohn; Ana P C P Carlotti; Michael D Cusimano; James T Rutka; Mitchell L Halperin
Cerebral salt wasting: truths, fallacies, theories, and challenges.
Critical care medicine 2002;30(11):2575-9.
2002: Yuh-Feng Lin; Shih-Hua Lin; Weng-Sheng Tsai; Mogamat Razeen Davids; Mitchell L Halperin
Severe hypokalaemia in a Chinese male.
QJM : monthly journal of the Association of Physicians 2002;95(10):695-704.
2002: Mogamat Razeen Davids; Yeouda Edoute; Robert L Jungas; Surinder Cheema-Dhadli; Mitchell L Halperin
Facilitating an understanding of integrative physiology: emphasis on the composition of body fluid compartments.
Canadian journal of physiology and pharmacology 2002;80(9):835-50.
2002: Troels Ring; Nine V A M Knoers; Man S Oh; Mitchell L Halperin
Reevaluation of the criteria for the clinical diagnosis of Gitelman syndrome.
Pediatric nephrology (Berlin, Germany) 2002;17(8):612-6.
2002: Mitchell L Halperin; Surinder Cheema-Dhadli; Ching-Bun Chen
Effect of fasting for two days on the excretion of ammonium in dogs with chronic metabolic acidosis.
Nephron 2002;91(4):695-700.
2002: David Z I Cherney; Mogamat Razeen Davids; Mitchell L Halperin
Acute hyponatraemia and 'ecstasy': insights from a quantitative and integrative analysis.
QJM : monthly journal of the Association of Physicians 2002;95(7):475-83.
2002: Ewout J Hoorn; Michiel G H Betjes; Robert Zietse; Mitchell L Halperin
[Clinical thinking and decision making in daily practice. An old man with hyponatremia].
Nederlands tijdschrift voor geneeskunde 2002;146(25):1206; author reply 1206.
2002: Surinder Cheema-Dhadli; Mitchell L Halperin
Influence of hypernatraemia and urea excretion on the ability to excrete a maximally hypertonic urine in the rat.
The Journal of physiology 2002;541(Pt 3):929-36.
2002: Surinder Cheema-Dhadli; Shih-Hua Lin; Mitchell L Halperin
Mechanisms used to dispose of progressively increasing alkali load in rats.
American journal of physiology. Renal physiology 2002;282(6):F1049-55.
2002: Shih-Hua Lin; Yuh-Feng Lin; Surinder Cheema-Dhadli; Mogamat Razeen Davids; Mitchell L Halperin
Hypercalcaemia and metabolic alkalosis with betel nut chewing: emphasis on its integrative pathophysiology.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(5):708-14.
2002: Mogamat Razeen Davids; S-H Lin; Yeouda Edoute; Surinder Cheema-Dhadli; Mitchell L Halperin
Hyponatraemia and hyperglycaemia during laproscopic surgery.
QJM : monthly journal of the Association of Physicians 2002;95(5):321-30.
2002: Mitchell L Halperin; Desmond Bohn
Clinical approach to disorders of salt and water balance. Emphasis on integrative physiology.
Critical care clinics 2002;18(2):249-72.
2002: Kamel S Kamel; Surinder Cheema-Dhadli; Mitchell L Halperin
Studies on the pathophysiology of the low urine pH in patients with uric acid stones.
Kidney international 2002;61(3):988-94.
2002: Mogamat Razeen Davids; Yeouda Edoute; S Stock; Mitchell L Halperin
Severe degree of hyperglycaemia: insights from integrative physiology.
QJM : monthly journal of the Association of Physicians 2002;95(2):113-24.
2002: Mogamat Razeen Davids; Yeouda Edoute; Jean-Pierre Mallie; Daniel G Bichet; Mitchell L Halperin
Body compartment volumes and composition after giving a vasopressin antagonist: changes are revealed by a tonicity balance.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17(2):300-3.
2002: Mohammad A Shafiee; Kamel S Kamel; Mitchell L Halperin
A conceptual approach to the patient with metabolic acidosis. Application to a patient with diabetic ketoacidosis.
Nephron 2002;92 Suppl 1():46-55.
2002: Kamel S Kamel; Man S Oh; Mitchell L Halperin
Bartter's, Gitelman's, and Gordon's syndromes. From physiology to molecular biology and back, yet still some unanswered questions.
Nephron 2002;92 Suppl 1():18-27.
2001: Mitchell L Halperin; Daniel G Bichet; Man S Oh
Integrative physiology of basal water permeability in the distal nephron: implications for the syndrome of inappropriate secretion of antidiuretic hormone.
Clinical nephrology 2001;56(5):339-45.
2001: Ana P C P Carlotti; Desmond Bohn; James T Rutka; Sheila Singh; W A Berry; A Sharman; Michael D Cusimano; Mitchell L Halperin
A method to estimate urinary electrolyte excretion in patients at risk for developing cerebral salt wasting.
Journal of neurosurgery 2001;95(3):420-4.
2001: Kamel S Kamel; Daniel G Bichet; Mitchell L Halperin
A patient with partial central diabetes insipidus: clarifying pathophysiology and designing treatment.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2001;37(6):1290-3.
2001: Ana P C P Carlotti; Desmond Bohn; Jean-Pierre Mallie; Mitchell L Halperin
Tonicity balance, and not electrolyte-free water calculations, more accurately guides therapy for acute changes in natremia.
Intensive care medicine 2001;27(5):921-4.
2001: M Halberthal; Mitchell L Halperin; Desmond Bohn
Lesson of the week: Acute hyponatraemia in children admitted to hospital: retrospective analysis of factors contributing to its development and resolution.
BMJ (Clinical research ed.) 2001;322(7289):780-2.
2001: Shih-Hua Lin; Yuh-Feng Lin; Mitchell L Halperin
Hypokalaemia and paralysis.
QJM : monthly journal of the Association of Physicians 2001;94(3):133-9.
2001: Mogamat Razeen Davids; Yeouda Edoute; Mitchell L Halperin
The approach to a patient with acute polyuria and hypernatremia: a need for the physiology of McCance at the bedside.
The Netherlands journal of medicine 2001;58(3):103-10.
2001: GF Zevallos; Dimitrios G Oreopoulos; Mitchell L Halperin
Hyponatremia in patients undergoing CAPD: role of water gain and/or malnutrition.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2001;21(1):72-6.
2001: D Z Cherney; GF Zevallos; Dimitrios G Oreopoulos; Mitchell L Halperin
A physiological analysis of hyponatremia: implications for patients on peritoneal dialysis.
Peritoneal dialysis international : journal of the International Society for Peritoneal Dialysis 2001;21(1):7-13.
2000: Mitchell L Halperin; Kamel S Kamel
Dynamic interactions between integrative physiology and molecular medicine: the key to understand the mechanism of action of aldosterone in the kidney.
Canadian journal of physiology and pharmacology 2000;78(8):587-94.
2000: G S Lam; J R Asplin; Mitchell L Halperin
Does a high concentration of calcium in the urine cause an important renal concentrating defect in human subjects?
Clinical science (London, England : 1979) 2000;98(3):313-9.
1998: Manjula Gowrishankar; S H Lin; Jean-Pierre Mallie; M S Oh; Mitchell L Halperin
Acute hyponatremia in the perioperative period: insights into its pathophysiology and recommendations for management.
Clinical nephrology 1998;50(6):352-60.
1998: Manjula Gowrishankar; Ching-Bun Chen; Surinder Cheema-Dhadli; Mitchell L Halperin
Prevention of acute hyponatremia by mannitol: an unanticipated mechanism.
Clinical nephrology 1998;50(5):295-300.
1998: Mitchell L Halperin; Kamel S Kamel
Potassium.
Lancet 1998;352(9122):135-40.
1998: Shih-Hua Lin; Surinder Cheema-Dhadli; S Chayaraks; Ching-Bun Chen; Manjula Gowrishankar; Mitchell L Halperin
Physiological disposal of the potential alkali load in diet of the rat: steps to achieve acid-base balance.
The American journal of physiology 1998;274(6 Pt 2):F1037-44.
1998: H Braden; Surinder Cheema-Dhadli; C David Mazer; D J McKnight; W Singer; Mitchell L Halperin
Hyperglycemia during normothermic cardiopulmonary bypass: the role of the kidney.
The Annals of thoracic surgery 1998;65(6):1588-93.
1998: S K Kamel; Shih-Hua Lin; Surinder Cheema-Dhadli; E B Marliss; Mitchell L Halperin
Prolonged total fasting: a feast for the integrative physiologist.
Kidney international 1998;53(3):531-9.
1998: Kamel S Kamel; E Harvey; K Douek; M S Parmar; Mitchell L Halperin
Studies on the pathogenesis of hypokalemia in Gitelman's syndrome: role of bicarbonaturia and hypomagnesemia.
American journal of nephrology 1998;18(1):42-9.
1998: Manjula Gowrishankar; I Lenga; Richard Y Cheung; Surinder Cheema-Dhadli; Mitchell L Halperin
Minimum urine flow rate during water deprivation: importance of the permeability of urea in the inner medulla.
Kidney international 1998;53(1):159-66.
1997: A Spira; Manjula Gowrishankar; Mitchell L Halperin
Factors contributing to the degree of polyuria in a patient with poorly controlled diabetes mellitus.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1997;30(6):829-35.
1997: S H Lin; Surinder Cheema-Dhadli; Manjula Gowrishankar; E B Marliss; Kamel S Kamel; Mitchell L Halperin
Control of excretion of potassium: lessons from studies during prolonged total fasting in human subjects.
The American journal of physiology 1997;273(5 Pt 2):F796-800.
1997: R Nagai; S W Kooh; J Williamson Balfe; T Fenton; Mitchell L Halperin
Renal tubular acidosis and osteopetrosis with carbonic anhydrase II deficiency: pathogenesis of impaired acidification.
Pediatric nephrology (Berlin, Germany) 1997;11(5):633-6.
1997: S D Soroka; S Chayaraks; Surinder Cheema-Dhadli; J A Myers; S Rubin; H Sonnenberg; Mitchell L Halperin
Minimum urine flow rate during water deprivation: importance of the nonurea versus total osmolality in the inner medulla.
Journal of the American Society of Nephrology : JASN 1997;8(6):880-6.
1997: Manjula Gowrishankar; Ching-Bun Chen; Surinder Cheema-Dhadli; A Steele; Mitchell L Halperin
Hyponatremia in the rat in the absence of positive water balance.
Journal of the American Society of Nephrology : JASN 1997;8(4):524-9.
1997: Jean-Pierre Mallie; D G Bichet; Mitchell L Halperin
Effective water clearance and tonicity balance: the excretion of water revisited.
Clinical and investigative medicine. Médecine clinique et experimentale 1997;20(1):16-24.
1997: Manjula Gowrishankar; D Sapir; Kenneth T Pace; Mitchell L Halperin
Profound natriuresis, extracellular fluid volume contraction, and hypernatremia with hypertonic losses following trauma.
Geriatric nephrology and urology 1997;7(2):95-100.
1997: Mitchell L Halperin; S D Soroka; Manjula Gowrishankar; H C Kim; J A Myers; S Rubin
Ensuring a minimum urine flow rate during water deprivation in chronic fasting.
Contributions to nephrology 1997;121():48-54.
1997: Mitchell L Halperin; A Gougoux; A Scheich
[Metabolic alkalosis on the surface but metabolic acidosis in depth].
Néphrologie 1997;18(1):11-6.
1997: Kamel S Kamel; L F Briceno; M I Sanchez; L Brenes; P Yorgin; S W Kooh; J Williamson Balfe; Mitchell L Halperin
A new classification for renal defects in net acid excretion.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1997;29(1):136-46.
1997: A Steele; Manjula Gowrishankar; Simon D Abrahamson; C David Mazer; R D Feldman; Mitchell L Halperin
Postoperative hyponatremia despite near-isotonic saline infusion: a phenomenon of desalination.
Annals of internal medicine 1997;126(1):20-5.
1996: S Laredo; K Yuen; B Sonnenberg; Mitchell L Halperin
Coexistence of central diabetes insipidus and salt wasting: the difficulties in diagnosis, changes in natremia, and treatment.
Journal of the American Society of Nephrology : JASN 1996;7(12):2527-32.
1996: Manjula Gowrishankar; Ching-Bun Chen; J P Mallie; Mitchell L Halperin
What is the impact of potassium excretion on the intracellular fluid volume: importance of urine anions.
Kidney international 1996;50(5):1490-5.
1996: F A Halperin; Surinder Cheema-Dhadli; Ching-Bun Chen; Mitchell L Halperin
Alkali therapy extends the period of survival during hypoxia: studies in rats.
The American journal of physiology 1996;271(2 Pt 2):R381-7.
1996: Kamel S Kamel; Surinder Cheema-Dhadli; F A Halperin; S Vasudevan; Mitchell L Halperin
Anion gap: may the anions restricted to the intravascular space undergo modification in their valence?
Nephron 1996;73(3):382-9.
1996: M Schreiber; L E Schlanger; Ching-Bun Chen; M Lessan-Pezeshki; Mitchell L Halperin; A Patnaik; BN Ling; Thomas R Kleyman
Antikaliuretic action of trimethoprim is minimized by raising urine pH.
Kidney international 1996;49(1):82-7.
1996: Mitchell L Halperin; Kamel S Kamel
D-lactic acidosis: turning sugar into acids in the gastrointestinal tract.
Kidney international 1996;49(1):1-8.
1996: Mitchell L Halperin; Manjula Gowrishankar; J P Mallie; H Sonnenberg; M Oh
Urea recycling: an aid to the excretion of potassium during antidiuresis.
Nephron 1996;72(4):507-11.
1995: Manjula Gowrishankar; Surinder Cheema-Dhadli; Mitchell L Halperin
Advances in diabetic ketoacidosis and hyperosmolar syndrome pathogenesis and management.
British journal of hospital medicine 1995;54(2-3):95-9.
1994: Mitchell L Halperin; Surinder Cheema-Dhadli; L E Phillip
Potassium excretion: a story that is easy to digest.
Journal of the American Society of Nephrology : JASN 1994;5(5 Suppl 1):S23-8.
1994: Kamel S Kamel; S Quaggin; A Scheich; Mitchell L Halperin
Disorders of potassium homeostasis: an approach based on pathophysiology.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1994;24(4):597-613.
1994: A Scheich; S Donnelly; Surinder Cheema-Dhadli; M Schweigert; S Vasuvattakul; Mitchell L Halperin
Does saline "correct" the abnormal mass balance in metabolic alkalosis associated with chloride depletion in the rat?
Clinical and investigative medicine. Médecine clinique et experimentale 1994;17(5):448-60.
1994: Kamel S Kamel; Mitchell L Halperin
Hyperkalemia with mild ECF volume contraction: studies to provide a possible physiologic interpretation.
Clinical and investigative medicine. Médecine clinique et experimentale 1994;17(5):414-9.
1994: A Steele; H deVeber; S E Quaggin; A Scheich; J Ethier; Mitchell L Halperin
What is responsible for the diurnal variation in potassium excretion?
The American journal of physiology 1994;267(2 Pt 2):R554-60.
1994: Mitchell L Halperin; Surinder Cheema-Dhadli; F A Halperin; Kamel S Kamel
Rationale for the use of sodium bicarbonate in a patient with lactic acidosis due to a poor cardiac output.
Nephron 1994;66(3):258-61.
1994: Mitchell L Halperin; A Scheich
Should we continue to recommend that a deficit of KCl be treated with NaCl? A fresh look at chloride-depletion metabolic alkalosis.
Nephron 1994;67(3):263-9.
1993: J M Goguen; Mitchell L Halperin
Can insulin administration cause an acute metabolic acidosis in vivo? An experimental study in dogs.
Diabetologia 1993;36(9):813-6.
1993: Mitchell L Halperin
Metabolic aspects of metabolic acidosis.
Clinical and investigative medicine. Médecine clinique et experimentale 1993;16(4):294-305.
1993: S Vasuvattakul; A Gougoux; Mitchell L Halperin
A method to evaluate renal ammoniagenesis in vivo.
Clinical and investigative medicine. Médecine clinique et experimentale 1993;16(4):265-73.
1993: S Vasuvattakul; S E Quaggin; A M Scheich; A Bayoumi; J M Goguen; Surinder Cheema-Dhadli; Mitchell L Halperin
Kaliuretic response to aldosterone: influence of the content of potassium in the diet.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1993;21(2):152-60.
1993: S Cheema-Dhadli; Mitchell L Halperin
Relative rates of appearance of nitrogen and sulphur: implications for postprandial synthesis of proteins.
Canadian journal of physiology and pharmacology 1993;71(2):120-7.
1993: Kamel S Kamel; R M Richardson; J M Goguen; A Fine; A Levin; Mitchell L Halperin
Rate of production of carbon dioxide in patients with a severe degree of metabolic acidosis.
Nephron 1993;64(4):514-7.
1992: Kamel S Kamel; Surinder Cheema-Dhadli; Mitchell L Halperin
Is accelerated oxidation of lactate required for dichloroacetate to lower the level of lactate in blood?
Canadian journal of physiology and pharmacology 1992;70(11):1477-82.
1992: Mitchell L Halperin; J M Goguen; Ching-Bun Chen
Fuel selection and the production of ammonium by the kidney: studies using insulin.
Canadian journal of physiology and pharmacology 1992;70(11):1437-41.
1992: U B Kaiser; J H Ethier; Kamel S Kamel; Mitchell L Halperin
Persistent hyperkalemia in a patient with diabetes mellitus: a reversible defect in kaliuresis during bicarbonaturia.
Clinical and investigative medicine. Médecine clinique et experimentale 1992;15(2):187-93.
1992: S Donnelly; Kamel S Kamel; S Vasuvattakul; RG Narins; Mitchell L Halperin
Might distal renal tubular acidosis be a proximal tubular cell disorder?
American journal of kidney diseases : the official journal of the National Kidney Foundation 1992;19(3):272-81.
1992: Kamel S Kamel; J H Ethier; S Quaggin; A Levin; S Albert; E J Carlisle; Mitchell L Halperin
Studies to determine the basis for hyperkalemia in recipients of a renal transplant who are treated with cyclosporine.
Journal of the American Society of Nephrology : JASN 1992;2(8):1279-84.
1992: S Vasuvattakul; L C Warner; Mitchell L Halperin
Quantitative role of the intracellular bicarbonate buffer system in response to an acute acid load.
The American journal of physiology 1992;262(2 Pt 2):R305-9.
1992: Mitchell L Halperin; Kamel S Kamel; Surinder Cheema-Dhadli
Lactic acidosis, ketoacidosis, and energy turnover: "figure" you made the correct diagnosis only when you have "counted" on it--quantitative analysis based on principles of metabolism.
The Mount Sinai journal of medicine, New York 1992;59(1):1-12.
1992: Mitchell L Halperin; Ching-Bun Chen
Energy turnover and the production of ammonium by the kidney: effect of hypernatremia.
Canadian journal of physiology and pharmacology 1992;70(1):8-12.
1992: Mitchell L Halperin; S Vasuvattakul; A Bayoumi
A modified classification of metabolic acidosis: a pathophysiologic approach.
Nephron 1992;60(2):129-33.
1991: Alexander K C Leung; W L Robson; Mitchell L Halperin
Polyuria in childhood.
Clinical pediatrics 1991;30(11):634-40.
1991: P O Magner; J H Ethier; Kamel S Kamel; Mitchell L Halperin
Interpretation of the urine osmolality: the role of ethanol and the rate of excretion of osmoles.
Clinical and investigative medicine. Médecine clinique et experimentale 1991;14(4):355-8.
1991: E J Carlisle; S M Donnelly; J H Ethier; S E Quaggin; U B Kaiser; S Vasuvattakul; Kamel S Kamel; Mitchell L Halperin
Modulation of the secretion of potassium by accompanying anions in humans.
Kidney international 1991;39(6):1206-12.
1991: E J Carlisle; S M Donnelly; Mitchell L Halperin
Renal tubular acidosis (RTA): recognize the ammonium defect and pHorget the urine pH.
Pediatric nephrology (Berlin, Germany) 1991;5(2):242-8.
1991: E J Carlisle; S M Donnelly; S Vasuvattakul; Kamel S Kamel; S Tobe; Mitchell L Halperin
Glue-sniffing and distal renal tubular acidosis: sticking to the facts.
Journal of the American Society of Nephrology : JASN 1991;1(8):1019-27.
1990: J H Ethier; U Honrath; AT Veress; H Sonnenberg; Mitchell L Halperin
Nephron site responsible for the reduced kaliuretic response to mineralocorticoids during hypokalemia in rats.
Kidney international 1990;38(5):812-7.
1990: Kamel S Kamel; J H Ethier; B J Stinebaugh; F X Schloeder; Mitchell L Halperin
Removal of an inorganic acid load in subjects with ketoacidosis of chronic fasting.
Kidney international 1990;38(3):507-11.
1990: Mitchell L Halperin; J H Ethier; Kamel S Kamel
The excretion of ammonium ions and acid base balance.
Clinical biochemistry 1990;23(3):185-8.
1990: Kamel S Kamel; J Ethier; A Levin; Mitchell L Halperin
Hypokalemia in the "beautiful people".
The American journal of medicine 1990;88(5):534-6.
1990: J H Ethier; Kamel S Kamel; P O Magner; J Lemann; Mitchell L Halperin
The transtubular potassium concentration in patients with hypokalemia and hyperkalemia.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1990;15(4):309-15.
1990: Mitchell L Halperin; B C Ching
Influence of acute hyponatremia on renal ammoniagenesis in dogs with chronic metabolic acidosis.
The American journal of physiology 1990;258(2 Pt 2):F328-32.
1990: P O Magner; Mitchell L Halperin
Effect of metabolic acidosis on glucose reabsorption in rats with acute hyperglycemia.
Canadian journal of physiology and pharmacology 1990;68(1):79-83.
1990: Kamel S Kamel; J H Ethier; R M Richardson; R A Bear; Mitchell L Halperin
Urine electrolytes and osmolality: when and how to use them.
American journal of nephrology 1990;10(2):89-102.
1989: Mitchell L Halperin; J H Ethier; Kamel S Kamel
Ammonium excretion in chronic metabolic acidosis: benefits and risks.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1989;14(4):267-71.
1989: Mitchell L Halperin
How much "new" bicarbonate is formed in the distal nephron in the process of net acid excretion?
Kidney international 1989;35(6):1277-81.
1989: Mitchell L Halperin; Surinder Cheema-Dhadli
Renal and hepatic aspects of ketoacidosis: a quantitative analysis based on energy turnover.
Diabetes/metabolism reviews 1989;5(4):321-36.
1989: Mitchell L Halperin; U Honrath; D R Wilson; H Sonnenberg
Effects of chronic hypokalaemia and adrenalectomy on potassium transport by the medullary collecting duct of the rat.
Clinical science (London, England : 1979) 1989;76(2):189-94.
1989: Mitchell L Halperin; Kamel S Kamel; J H Ethier; P O Magner
What is the underlying defect in patients with isolated, proximal renal tubular acidosis?
American journal of nephrology 1989;9(4):265-8.
1989: Kamel S Kamel; P O Magner; J H Ethier; Mitchell L Halperin
Urine electrolytes in the assessment of extracellular fluid volume contraction.
American journal of nephrology 1989;9(4):344-7.
1988: F J Haynes; Surinder Cheema-Dhadli; R M Halperin; R Zettle; L Robinson; Mitchell L Halperin
Effect of anaesthesia on insulin-induced hypoglycemia in rabbits.
Canadian journal of physiology and pharmacology 1988;66(12):1531-7.
1988: W Aird; K Douek; Mitchell L Halperin
Profound hypokalemia secondary to modest potassium depletion in a patient with coexisting hyponatremia: therapeutic implications.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1988;12(2):164-6.
1988: Lawrence A Leiter; Robert G Josse; M L West; Mitchell L Halperin
Severe metabolic acidosis induced in a patient during fasting by KCl administration.
Clinical and investigative medicine. Médecine clinique et experimentale 1988;11(4):266-70.
1988: Mitchell L Halperin; Benjamin L Margolis; L A Robinson; R M Halperin; M L West; R A Bear
The urine osmolal gap: a clue to estimate urine ammonium in "hybrid" types of metabolic acidosis.
Clinical and investigative medicine. Médecine clinique et experimentale 1988;11(3):198-202.
1988: P O Magner; L Robinson; R M Halperin; R Zettle; Mitchell L Halperin
The plasma potassium concentration in metabolic acidosis: a re-evaluation.
American journal of kidney diseases : the official journal of the National Kidney Foundation 1988;11(3):220-4.
1988: Mitchell L Halperin; R M Richardson; R A Bear; P O Magner; Kamel S Kamel; J Ethier
Urine ammonium: the key to the diagnosis of distal renal tubular acidosis.
Nephron 1988;50(1):1-4.
1988: M L West; P O Magner; R M Richardson; Mitchell L Halperin
A renal mechanism limiting the degree of potassium loss in severely hyperglycemic patients.
American journal of nephrology 1988;8(5):373-8.
1987: Mitchell L Halperin; Surinder Cheema-Dhadli; K S Desai; Cecil C Yip; R L Jungas
Interaction of insulin with its receptor. I. Possible role of a histidine-arginine interaction.
Clinical and investigative medicine. Médecine clinique et experimentale 1987;10(5):395-400.
1987: M L West; H Sonnenberg; AT Veress; Mitchell L Halperin
The relationship between the plasma potassium concentration and renal potassium excretion in the adrenalectomized rat.
Clinical science (London, England : 1979) 1987;72(5):577-83.
1987: Surinder Cheema-Dhadli; R L Jungas; Mitchell L Halperin
Regulation of urea synthesis by acid-base balance in vivo: role of NH3 concentration.
The American journal of physiology 1987;252(2 Pt 2):F221-5.
1987: R M Zettle; M L West; Ching-Bun Chen; Mitchell L Halperin
Does the kidney 'escape' from the kaliuretic action of mineralocorticoids?
Mineral and electrolyte metabolism 1987;13(5):340-6.
1987: R M Zettle; M L West; Robert G Josse; R M Richardson; P A Marsden; Mitchell L Halperin
Renal potassium handling during states of low aldosterone bio-activity: a method to differentiate renal and non-renal causes.
American journal of nephrology 1987;7(5):360-6.
1986: MB Goldstein; R Bear; R M Richardson; P A Marsden; Mitchell L Halperin
The urine anion gap: a clinically useful index of ammonium excretion.
The American journal of the medical sciences 1986;292(4):198-202.
1986: M L West; P A Marsden; G G Singer; Mitchell L Halperin
Quantitative analysis of glucose loss during acute therapy for hyperglycemic hyperosmolar syndrome.
Diabetes care 1986;9(5):465-71.
1986: Mitchell L Halperin; Ching-Bun Chen; Surinder Cheema-Dhadli; M L West; R L Jungas
Is urea formation regulated primarily by acid-base balance in vivo?
The American journal of physiology 1986;250(4 Pt 2):F605-12.
1986: M L West; P A Marsden; R M Richardson; R M Zettle; Mitchell L Halperin
New clinical approach to evaluate disorders of potassium excretion.
Mineral and electrolyte metabolism 1986;12(4):234-8.
1986: M L West; O Bendz; Ching-Bun Chen; G G Singer; R M Richardson; H Sonnenberg; Mitchell L Halperin
Development of a test to evaluate the transtubular potassium concentration gradient in the cortical collecting duct in vivo.
Mineral and electrolyte metabolism 1986;12(4):226-33.
1986: Mitchell L Halperin; Surinder Cheema-Dhadli; F J Haynes; Cecil C Yip
A theoretical analysis of the turnover of the hepatic insulin receptor in the rat.
Clinical and investigative medicine. Médecine clinique et experimentale 1986;9(2):141-3.
1985: Mitchell L Halperin; Ching-Bun Chen; Surinder Cheema-Dhadli
Effect of the blood lactate concentration on renal glutamine metabolism in dogs with chronic metabolic acidosis.
Canadian journal of physiology and pharmacology 1985;63(12):1570-6.
1985: Mitchell L Halperin; P Vinay; A Gougoux; C Pichette; R L Jungas
Regulation of the maximum rate of renal ammoniagenesis in the acidotic dog.
The American journal of physiology 1985;248(4 Pt 2):F607-15.
1985: Mitchell L Halperin; P A Marsden; G G Singer; M L West
Can marked hyperglycemia occur without ketosis?
Clinical and investigative medicine. Médecine clinique et experimentale 1985;8(4):253-6.
1985: Mitchell L Halperin; MB Goldstein; R M Richardson; B J Stinebaugh
Distal renal tubular acidosis syndromes: a pathophysiological approach.
American journal of nephrology 1985;5(1):1-8.
1983: Mitchell L Halperin; MB Goldstein; C Pichette; R L Jungas; B J Stinebaugh
Evaluation of the bicarbonate buffer system. Does the pK' really vary in the blood?
American journal of nephrology 1983;3(5):245-7.
1983: M Bercovici; Ching-Bun Chen; MB Goldstein; B J Steinbaugh; Mitchell L Halperin
Effect of acute changes in the PaCO2 on acid-base parameters in normal dogs and dogs with metabolic acidosis or alkalosis.
Canadian journal of physiology and pharmacology 1983;61(2):166-73.
1983: H J Adrogué; B J Stinebaugh; A Gougoux; G Lemieux; P Vinay; S C Tam; MB Goldstein; Mitchell L Halperin
Decreased distal acidification in acute hypercapnia in the dog.
The American journal of physiology 1983;244(1):F19-27.
1982: Mitchell L Halperin; R L Jungas; C Pichette; MB Goldstein
A quantitative analysis of renal ammoniagenesis and energy balance: a theoretical approach.
Canadian journal of physiology and pharmacology 1982;60(12):1431-5.
1982: M C Hannaford; Lawrence A Leiter; Robert G Josse; MB Goldstein; E B Marliss; Mitchell L Halperin
Protein wasting due to acidosis of prolonged fasting.
The American journal of physiology 1982;243(3):E251-6.
1982: M C Hannaford; MB Goldstein; Robert G Josse; Mitchell L Halperin
Role of acidosis in the protein wasting of fasting in the rat and the rabbit.
Canadian journal of physiology and pharmacology 1982;60(3):331-4.
1982: Mitchell L Halperin; MB Goldstein; B J Stinebaugh; I M Sajo; D R Wilson; H Sonnenberg
Segmental analysis of ammonia movement into and out of the nephron.
Contributions to nephrology 1982;31():16-22.
1981: A Gougoux; P Vinay; G Lemieux; M A Duran; Ching-Bun Chen; MB Goldstein; B J Stinebauch; S C Tam; Mitchell L Halperin
Studies on the mechanism whereby acidemia stimulates collecting duct hydrogen ion secretion in vivo.
Kidney international 1981;20(5):643-8.
1981: S C Tam; MB Goldstein; B J Stinebaugh; Ching-Bun Chen; A Gougoux; Mitchell L Halperin
Studies on the regulation of hydrogen ion secretion in the collecting duct in vivo: evaluation of factors that influence the urine minus blood PCO2 difference.
Kidney international 1981;20(5):636-42.
1981: I M Sajo; MB Goldstein; H Sonnenberg; B J Stinebaugh; D R Wilson; Mitchell L Halperin
Sites of ammonia addition to tubular fluid in rats with chronic metabolic acidosis.
Kidney international 1981;20(3):353-8.
1981: Mitchell L Halperin; R A Bear; M C Hannaford; MB Goldstein
Selected aspects of the pathophysiology of metabolic acidosis in diabetes mellitus.
Diabetes 1981;30(9):781-7.
1981: S C Tam; MB Goldstein; Ching-Bun Chen; Mitchell L Halperin; B J Stinebaugh
Implications of the finding of calcium carbonate in rabbit urine with respect to renal acidification.
Canadian journal of physiology and pharmacology 1981;59(8):800-5.
1981: W L Robson; C E Bayliss; R Feldman; MB Goldstein; Ching-Bun Chen; R M Richardson; B J Stinebaugh; S C Tam; Mitchell L Halperin
Evaluation of the effect of pentobarbitone anaesthesia on the plasma potassium concentration in the rabbit and the dog.
Canadian Anaesthetists' Society journal 1981;28(3):210-6.
1981: W L Robson; Mitchell L Halperin; B J Stinebaugh; MB Goldstein
Effect of mineralocorticoids on collecting duct hydrogen ion secretion in the rabbit.
Canadian journal of physiology and pharmacology 1981;59(3):235-8.
1981: H Sonnenberg; S Cheema-Dhadli; MB Goldstein; B J Stinebaugh; D R Wilson; Mitchell L Halperin
Ammonia addition into the medullary collecting duct of the rat.
Kidney international 1981;19(2):281-7.
1981: B J Stinebaugh; F X Schloeder; S C Tam; MB Goldstein; Mitchell L Halperin
Pathogenesis of distal renal tubular acidosis.
Kidney international 1981;19(1):1-7.
1980: S C Tam; MB Goldstein; R M Richardson; W L Robson; B J Stinebaugh; Mitchell L Halperin
Effect of extracellular fluid volume contraction on distal-nephron hydrogen ion secretion in vivo.
The Journal of laboratory and clinical medicine 1980;96(3):442-9.
1980: Mitchell L Halperin; MB Goldstein; I Sajo; S C Tam
Sodium: water ratio in CSF and serum.
Diabetes care 1980;3(4):569-70.
1980: A Gougoux; P Vinay; G Lemieux; R M Richardson; S Tam; MB Goldstein; B J Stinebaugh; Mitchell L Halperin
Effect of blood pH on distal nephron hydrogen ion secretion.
Kidney international 1980;17(5):615-21.
1980: B J Stinebaugh; R Esquenazi; F X Schloeder; W N Suki; MB Goldstein; Mitchell L Halperin
Control of the urine-blood PCO2 gradient in alkaline urine.
Kidney international 1980;17(1):31-9.