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MJ Halsey

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Edmond I Eger; MJ Halsey; DD Koblin; Michael J Laster; P Ionescu; K Königsberger; R Fan; B V Nguyen; T Hudlicky
The convulsant and anesthetic properties of cis-trans isomers of 1,2-dichlorohexafluorocyclobutane and 1,2-dichloroethylene.
Edmond I Eger; MJ Halsey; R Adron Harris; DD Koblin; A Pohorille; J C Sewell; James M Sonner; James R Trudell
Hypothesis: volatile anesthetics produce immobility by acting on two sites approximately five carbon atoms apart.
DD Koblin; Michael J Laster; P Ionescu; Diane Gong; Edmond I Eger; MJ Halsey; T Hudlicky
Polyhalogenated methyl ethyl ethers: solubilities and anesthetic properties.

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2001: Edmond I Eger; MJ Halsey; DD Koblin; Michael J Laster; P Ionescu; K Königsberger; R Fan; B V Nguyen; T Hudlicky
The convulsant and anesthetic properties of cis-trans isomers of 1,2-dichlorohexafluorocyclobutane and 1,2-dichloroethylene.
Anesthesia and analgesia 2001;93(4):922-7.
1999: Edmond I Eger; MJ Halsey; R Adron Harris; DD Koblin; A Pohorille; J C Sewell; James M Sonner; James R Trudell
Hypothesis: volatile anesthetics produce immobility by acting on two sites approximately five carbon atoms apart.
Anesthesia and analgesia 1999;88(6):1395-400.
1999: DD Koblin; Michael J Laster; P Ionescu; Diane Gong; Edmond I Eger; MJ Halsey; T Hudlicky
Polyhalogenated methyl ethyl ethers: solubilities and anesthetic properties.
Anesthesia and analgesia 1999;88(5):1161-7.
1999: Edmond I Eger; DD Koblin; James M Sonner; Diane Gong; Michael J Laster; P Ionescu; MJ Halsey; T Hudlicky
Nonimmobilizers and transitional compounds may produce convulsions by two mechanisms.
Anesthesia and analgesia 1999;88(4):884-92.
1998: J C Sewell; MJ Halsey
Molecular similarity analysis: an alternative approach to studying molecular mechanisms of anaesthesia.
Toxicology letters 1998;100-101():359-64.
1998: DD Koblin; Z Fang; Edmond I Eger; Michael J Laster; Diane Gong; P Ionescu; MJ Halsey; James R Trudell
Minimum alveolar concentrations of noble gases, nitrogen, and sulfur hexafluoride in rats: helium and neon as nonimmobilizers (nonanesthetics)
Anesthesia and analgesia 1998;87(2):419-24.
1997: Z Fang; Michael J Laster; P Ionescu; DD Koblin; James M Sonner; Edmond I Eger; MJ Halsey
Effects of inhaled nonimmobilizer, proconvulsant compounds on desflurane minimum alveolar anesthetic concentration in rats.
Anesthesia and analgesia 1997;85(5):1149-53.
1997: Edmond I Eger; DD Koblin; R Adron Harris; Joan J Kendig; A Pohorille; MJ Halsey; James R Trudell
Hypothesis: inhaled anesthetics produce immobility and amnesia by different mechanisms at different sites.
Anesthesia and analgesia 1997;84(4):915-8.
1997: Z Fang; Michael J Laster; Diane Gong; P Ionescu; DD Koblin; James M Sonner; Edmond I Eger; MJ Halsey
Convulsant activity of nonanesthetic gas combinations.
Anesthesia and analgesia 1997;84(3):634-40.
1996: Z Fang; James M Sonner; Michael J Laster; P Ionescu; L Kandel; DD Koblin; Edmond I Eger; MJ Halsey
Anesthetic and convulsant properties of aromatic compounds and cycloalkanes: implications for mechanisms of narcosis.
Anesthesia and analgesia 1996;83(5):1097-104.
1994: J Liu; Michael J Laster; S Taheri; Edmond I Eger; B Chortkoff; MJ Halsey
Effect of n-alkane kinetics in rats on potency estimations and the Meyer-Overton hypothesis.
Anesthesia and analgesia 1994;79(6):1049-55.
1994: DD Koblin; B S Chortkoff; Michael J Laster; Edmond I Eger; MJ Halsey; P Ionescu
Polyhalogenated and perfluorinated compounds that disobey the Meyer-Overton hypothesis.
Anesthesia and analgesia 1994;79(6):1043-8.
1994: Edmond I Eger; J Liu; DD Koblin; Michael J Laster; S Taheri; MJ Halsey; P Ionescu; B S Chortkoff; T Hudlicky
Molecular properties of the "ideal" inhaled anesthetic: studies of fluorinated methanes, ethanes, propanes, and butanes.
Anesthesia and analgesia 1994;79(2):245-51.
1994: J Liu; Michael J Laster; DD Koblin; Edmond I Eger; MJ Halsey; S Taheri; B Chortkoff
A cutoff in potency exists in the perfluoroalkanes.
Anesthesia and analgesia 1994;79(2):238-44.
1994: B S Chortkoff; Michael J Laster; DD Koblin; S Taheri; Edmond I Eger; MJ Halsey
Pharmacokinetics do not explain the absence of an anesthetic effect of perfluoropropane or perfluoropentane.
Anesthesia and analgesia 1994;79(2):234-7.
1993: S Taheri; Michael J Laster; J Liu; Edmond I Eger; MJ Halsey; DD Koblin
Anesthesia by n-alkanes not consistent with the Meyer-Overton hypothesis: determinations of the solubilities of alkanes in saline and various lipids.
Anesthesia and analgesia 1993;77(1):7-11.
1993: J Liu; Michael J Laster; S Taheri; Edmond I Eger; DD Koblin; MJ Halsey
Is there a cutoff in anesthetic potency for the normal alkanes?
Anesthesia and analgesia 1993;77(1):12-8.
1991: S Taheri; MJ Halsey; J Liu; Edmond I Eger; DD Koblin; Michael J Laster
What solvent best represents the site of action of inhaled anesthetics in humans, rats, and dogs?
Anesthesia and analgesia 1991;72(5):627-34.