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Charles Halsted

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TOP 3
Valentina Medici; Charles H Halsted
Folate, alcohol, and liver disease.
Charles H Halsted
B-Vitamin dependent methionine metabolism and alcoholic liver disease.
Valentina Medici; Noreene M Shibata; Natalie J Török; Rima Woods; Peter J Havel; Joy X Jiang; Kusum K Kharbanda; Kyoungmi Kim; Janine M LaSalle; Sarah Liu; Bo Lonnerdal; Sridevi Devaraj; Jesse A Engelberg; Charles H Halsted
Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.

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All Publications

2013: Valentina Medici; Charles H Halsted
Folate, alcohol, and liver disease.
Molecular nutrition & food research 2013;57(4):596-606.
2013: Charles H Halsted
B-Vitamin dependent methionine metabolism and alcoholic liver disease.
Clinical chemistry and laboratory medicine : CCLM / FESCC 2013;51(3):457-65.
2013: Valentina Medici; Noreene M Shibata; Natalie J Török; Rima Woods; Peter J Havel; Joy X Jiang; Kusum K Kharbanda; Kyoungmi Kim; Janine M LaSalle; Sarah Liu; Bo Lonnerdal; Sridevi Devaraj; Jesse A Engelberg; Charles H Halsted
Wilson's disease: changes in methionine metabolism and inflammation affect global DNA methylation in early liver disease.
Hepatology (Baltimore, Md.) 2013;57(2):555-65.
2012: Charles H Halsted; Valentina Medici
Aberrant hepatic methionine metabolism and gene methylation in the pathogenesis and treatment of alcoholic steatohepatitis.
International journal of hepatology 2012;2012():959746.
2011: Charles H Halsted; Valentina Medici
Vitamin-dependent methionine metabolism and alcoholic liver disease.
Advances in nutrition (Bethesda, Md.) 2011;2(5):421-7.
2010: Valentina Medici; Janet M Peerson; Sally P Stabler; Samuel W French; Jesse F Gregory; Maria Catrina Virata; Antony Albanese; Christopher L Bowlus; Sridevi Devaraj; Edward A Panacek; Nazir Rahim; John R Richards; Lorenzo Rossaro; Charles H Halsted
Impaired homocysteine transsulfuration is an indicator of alcoholic liver disease.
Journal of hepatology 2010;53(3):551-7.
2010: Farah Esfandiari; Valentina Medici; Donna H Wong; Soumia Jose; Maryam Dolatshahi; Eoin Quinlivan; Sanjana Dayal; Steven R Lentz; Hidekazu Tsukamoto; Yue Hua Zhang; Samuel W French; Charles H Halsted
Epigenetic regulation of hepatic endoplasmic reticulum stress pathways in the ethanol-fed cystathionine beta synthase-deficient mouse.
Hepatology (Baltimore, Md.) 2010;51(3):932-41.
2009: Angela M. Zivkovic; J Bruce German; Farah Esfandiari; Charles H Halsted
Quantitative lipid metabolomic changes in alcoholic micropigs with fatty liver disease.
Alcoholism, clinical and experimental research 2009;33(4):751-8.
2008: Charles H Halsted
Perspectives on obesity and sweeteners, folic acid fortification and vitamin D requirements.
Family practice 2008;25 Suppl 1():i44-9.
2008: Joshua L Roffman; Anthony P Weiss; Thilo Deckersbach; Oliver Freudenreich; David C Henderson; Donna H Wong; Charles H Halsted; Donald C Goff
Interactive effects of COMT Val108/158Met and MTHFR C677T on executive function in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2008;147B(6):990-5.
2008: Joshua L Roffman; Anthony P Weiss; Shaun Purcell; Christopher A Caffalette; Oliver Freudenreich; David C Henderson; Teodoro Bottiglieri; Donna H Wong; Charles H Halsted; Donald C Goff
Contribution of methylenetetrahydrofolate reductase (MTHFR) polymorphisms to negative symptoms in schizophrenia.
Biological psychiatry 2008;63(1):42-8.
2007: Fataneh Amidi; Barbara A French; David Chung; Charles H Halsted; Valentina Medici; Samuel W French
M-30 and 4HNE are sequestered in different aggresomes in the same hepatocytes.
Experimental and molecular pathology 2007;83(3):296-300.
2007: Jesus A Villanueva; Farah Esfandiari; Mollie E White; Sridevi Devaraj; Samuel W French; Charles H Halsted
S-adenosylmethionine attenuates oxidative liver injury in micropigs fed ethanol with a folate-deficient diet.
Alcoholism, clinical and experimental research 2007;31(11):1934-43.
2007: Yalin Liao; Veronica Lopez; Tracy B Shafizadeh; Charles H Halsted; Bo Lonnerdal
Cloning of a pig homologue of the human lactoferrin receptor: expression and localization during intestinal maturation in piglets.
Comparative biochemistry and physiology. Part A, Molecular & integrative physiology 2007;148(3):584-90.
2007: Charles H Halsted; Donna H Wong; Janet M Peerson; Craig H Warden; Helga Refsum; A David Smith; Ottar Nygård; Per Magne Ueland; Stein Emil Vollset; Grethe S Tell
Relations of glutamate carboxypeptidase II (GCPII) polymorphisms to folate and homocysteine concentrations and to scores of cognition, anxiety, and depression in a homogeneous Norwegian population: the Hordaland Homocysteine Study.
The American journal of clinical nutrition 2007;86(2):514-21.
2007: Vishnudutt Purohit; Manal F Abdelmalek; Shirish Barve; Norlin J Benevenga; Charles H Halsted; Neil Kaplowitz; Kusum K Kharbanda; Qi-Ying Liu; Shelly C Lu; Craig J McClain; Christine Swanson; Samir Zakhari
Role of S-adenosylmethionine, folate, and betaine in the treatment of alcoholic liver disease: summary of a symposium.
The American journal of clinical nutrition 2007;86(1):14-24.
2007: Farah Esfandiari; Min You; Jesus A Villanueva; Donna H Wong; Samuel W French; Charles H Halsted
S-adenosylmethionine attenuates hepatic lipid synthesis in micropigs fed ethanol with a folate-deficient diet.
Alcoholism, clinical and experimental research 2007;31(7):1231-9.
2007: Tracy B Shafizadeh; Charles H Halsted
gamma-Glutamyl hydrolase, not glutamate carboxypeptidase II, hydrolyzes dietary folate in rat small intestine.
The Journal of nutrition 2007;137(5):1149-53.
2007: Joshua L Roffman; Anthony P Weiss; Thilo Deckersbach; Oliver Freudenreich; David C Henderson; Shaun Purcell; Donna H Wong; Charles H Halsted; Donald C Goff
Effects of the methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism on executive function in schizophrenia.
Schizophrenia research 2007;92(1-3):181-8.
2007: Lynn M Wallock-Montelius; Jesus A Villanueva; Robert Chapin; Alan J Conley; Hung P Nguyen; Bruce N Ames; Charles H Halsted
Chronic ethanol perturbs testicular folate metabolism and dietary folate deficiency reduces sex hormone levels in the Yucatan micropig.
Biology of reproduction 2007;76(3):455-65.
2006: S Jill James; Stepan Melnyk; Stefanie Jernigan; Mario A Cleves; Charles H Halsted; Donna H Wong; Paul Cutler; Kenneth Bock; Marvin Boris; J Jeffrey Bradstreet; Sidney M Baker; David W Gaylor
Metabolic endophenotype and related genotypes are associated with oxidative stress in children with autism.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2006;141B(8):947-56.
2006: Jesus A Villanueva; Farah Esfandiari; Donna H Wong; Iram Ahmad; Stepan Melnyk; S Jill James; Charles H Halsted
Abnormal transsulfuration and glutathione metabolism in the micropig model of alcoholic liver disease.
Alcoholism, clinical and experimental research 2006;30(7):1262-70.
2006: Angela M Devlin; Robert Clarke; Jacqueline Birks; John Grimley Evans; Charles H Halsted
Interactions among polymorphisms in folate-metabolizing genes and serum total homocysteine concentrations in a healthy elderly population.
The American journal of clinical nutrition 2006;83(3):708-13.
2005: Charles H Halsted; Ronenn Roubenoff
Response of the American Journal of Clinical Nutrition to the National Institutes of Health Public Access Policy.
The American journal of clinical nutrition 2005;82(2):275-6.
2005: Farah Esfandiari; Jesus A Villanueva; Donna H Wong; Samuel W French; Charles H Halsted
Chronic ethanol feeding and folate deficiency activate hepatic endoplasmic reticulum stress pathway in micropigs.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(1):G54-63.
2004: Charles H Halsted
Nutrition and alcoholic liver disease.
Seminars in liver disease 2004;24(3):289-304.
2004: Jesus A Villanueva; Charles H Halsted
Hepatic transmethylation reactions in micropigs with alcoholic liver disease.
Hepatology (Baltimore, Md.) 2004;39(5):1303-10.
2003: Charles H Halsted
Copyright protection and open access.
The American journal of clinical nutrition 2003;78(5):899-901.
2003: Isabelle Morin; Angela M Devlin; Daniel Leclerc; Nelly Sabbaghian; Charles H Halsted; Richard Finnell; Rima Rozen
Evaluation of genetic variants in the reduced folate carrier and in glutamate carboxypeptidase II for spina bifida risk.
Molecular genetics and metabolism 2003;79(3):197-200.
2003: Charles H Halsted
Dietary supplements and functional foods: 2 sides of a coin?
The American journal of clinical nutrition 2003;77(4 Suppl):1001S-1007S.
2003: Charles H Halsted
Victor Herbert, MD, 1927-2002.
The American journal of clinical nutrition 2003;77(4):757-9.
2003: Charles H Halsted
Absorption of water-soluble vitamins.
Current opinion in gastroenterology 2003;19(2):113-7.
2003: Charles H Halsted
We are fifty.
The American journal of clinical nutrition 2003;77(1):1-2.
2002: Charles H Halsted; Jesus A Villanueva; Angela M Devlin; Carol J Chandler
Metabolic interactions of alcohol and folate.
The Journal of nutrition 2002;132(8 Suppl):2367S-2372S.
2002: Charles H Halsted; Jesus A Villanueva; Angela M Devlin; Onni Niemelä; Seppo Parkkila; Timothy A Garrow; Lynn M Wallock; Mark K Shigenaga; Stepan Melnyk; S Jill James
Folate deficiency disturbs hepatic methionine metabolism and promotes liver injury in the ethanol-fed micropig.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(15):10072-7.
2002: Charles H Halsted; Jesus A Villanueva; Angela M Devlin
Folate deficiency, methionine metabolism, and alcoholic liver disease.
Alcohol (Fayetteville, N.Y.) 2002;27(3):169-72.
2002: Charles H Halsted; Jesus A Villanueva; Angela M Devlin; S Jill James
Interactions of ethanol and folate deficiency in development of alcoholic liver disease in the micropig.
Transactions of the American Clinical and Climatological Association 2002;113():151-62; discussion 162-3.
2001: Jesus A Villanueva; Angela M Devlin; Charles H Halsted
Reduced folate carrier: tissue distribution and effects of chronic ethanol intake in the micropig.
Alcoholism, clinical and experimental research 2001;25(3):415-20.
2000: Angela M Devlin; EH Ling; Janet M Peerson; S Fernando; Robert Clarke; A David Smith; Charles H Halsted
Glutamate carboxypeptidase II: a polymorphism associated with lower levels of serum folate and hyperhomocysteinemia.
Human molecular genetics 2000;9(19):2837-44.
1999: Seppo Parkkila; Charles H Halsted; Jesus A Villanueva; H Kalervo Väänänen; Onni Niemelä
Expression of testosterone-dependent enzyme, carbonic anhydrase III, and oxidative stress in experimental alcoholic liver disease.
Digestive diseases and sciences 1999;44(11):2205-13.
1999: Onni Niemelä; Seppo Parkkila; Markku Pasanen; Katja Viitala; Jesus A Villanueva; Charles H Halsted
Induction of cytochrome P450 enzymes and generation of protein-aldehyde adducts are associated with sex-dependent sensitivity to alcohol-induced liver disease in micropigs.
Hepatology (Baltimore, Md.) 1999;30(4):1011-7.
1999: Charles H Halsted
Obesity: effects on the liver and gastrointestinal system.
Current opinion in clinical nutrition and metabolic care 1999;2(5):425-9.
1999: Charles H Halsted
The relevance of clinical nutrition education and role models to the practice of medicine.
European journal of clinical nutrition 1999;53 Suppl 2():S29-34.
1999: Charles H Halsted
Obesity: effects on the liver and gastrointestinal system.
Current opinion in gastroenterology 1999;15(2):154-8.
1998: J Villanueva; EH Ling; C J Chandler; Charles H Halsted
Membrane and tissue distribution of folate binding protein in pig.
The American journal of physiology 1998;275(5 Pt 2):R1503-10.
1998: Charles H Halsted; EH Ling; Ruth Luthi-Carter; Jesus A Villanueva; J M Gardner; Joseph T Coyle
Folylpoly-gamma-glutamate carboxypeptidase from pig jejunum. Molecular characterization and relation to glutamate carboxypeptidase II.
The Journal of biological chemistry 1998;273(32):20417-24.
1998: Charles H Halsted
Clinical nutrition education--relevance and role models.
The American journal of clinical nutrition 1998;67(2):192-6.
1997: C M Van Hoozen; P G Peeke; MW Taubeneck; Charles F Frey; Charles H Halsted
Efficacy of enzyme supplementation after surgery for chronic pancreatitis.
Pancreas 1997;14(2):174-80.
1996: C M Van Hoozen; E H Ling; Charles H Halsted
Folate binding protein: molecular characterization and transcript distribution in pig liver, kidney and jejunum.
The Biochemical journal 1996;319 ( Pt 3)():725-9.
1996: Charles H Halsted; J Villanueva; C J Chandler; S P Stabler; R H Allen; Levan Muskhelishvili; S Jill James; L Poirier
Ethanol feeding of micropigs alters methionine metabolism and increases hepatocellular apoptosis and proliferation.
Hepatology (Baltimore, Md.) 1996;23(3):497-505.
1995: Onni Niemelä; S Parkkila; S Ylä-Herttuala; J Villanueva; Boris Henry Ruebner; Charles H Halsted
Sequential acetaldehyde production, lipid peroxidation, and fibrogenesis in micropig model of alcohol-induced liver disease.
Hepatology (Baltimore, Md.) 1995;22(4 Pt 1):1208-14.
1995: Charles H Halsted
Certification of clinical nutritionists.
The American journal of clinical nutrition 1995;62(1):10-2.
1995: A B Balatbat; G W Jordan; Charles H Halsted
Congenital malaria in a nonidentical twin.
The Western journal of medicine 1995;162(5):458-9.
1994: J D Stone; C C Heise; Christopher J Miller; Charles H Halsted; Satya Dandekar
Development of malabsorption and nutritional complications in simian immunodeficiency virus-infected rhesus macaques.
AIDS (London, England) 1994;8(9):1245-56.
1994: J Villanueva; C J Chandler; N Shimasaki; A B Tang; M Nakamura; stephen phinney; Charles H Halsted
Effects of ethanol feeding on liver, kidney and jejunal membranes of micropigs.
Hepatology (Baltimore, Md.) 1994;19(5):1229-40.
1994: M T Nakamura; A B Tang; J Villanueva; Charles H Halsted; stephen phinney
Selective reduction of delta 6 and delta 5 desaturase activities but not delta 9 desaturase in micropigs chronically fed ethanol.
The Journal of clinical investigation 1994;93(1):450-4.
1993: M T Nakamura; A B Tang; J Villanueva; Charles H Halsted; stephen phinney
The body composition and lipid metabolic effects of long-term ethanol feeding during a high omega 6 polyunsaturated fatty acid diet in micropigs.
Metabolism: clinical and experimental 1993;42(10):1340-50.
1993: Charles H Halsted; J Villanueva; C J Chandler; Boris Henry Ruebner; R J Munn; S Parkkila; Onni Niemelä
Centrilobular distribution of acetaldehyde and collagen in the ethanol-fed micropig.
Hepatology (Baltimore, Md.) 1993;18(4):954-60.
1993: C Heise; Peter Vogel; Christopher J Miller; Charles H Halsted; Satya Dandekar
Simian immunodeficiency virus infection of the gastrointestinal tract of rhesus macaques. Functional, pathological, and morphological changes.
The American journal of pathology 1993;142(6):1759-71.
1993: David Heber; Charles H Halsted; C M Brooks; R W Chesney; M DiGirolamo; Douglas C Heimburger; Donald D Hensrud; D A Mark; M D Sitrin; H H Tillman
Biennial survey of physician clinical-nutrition training programs.
The American journal of clinical nutrition 1993;57(4):463-9.
1992: M T Nakamura; A B Tang; J Villanueva; Charles H Halsted; stephen phinney
Reduced tissue arachidonic acid concentration with chronic ethanol feeding in miniature pigs.
The American journal of clinical nutrition 1992;56(3):467-74.
1992: Charles H Halsted
Toward standardized training of physicians in clinical nutrition.
The American journal of clinical nutrition 1992;56(1):1-3.
1991: Charles H Halsted
Jejunal brush-border folate hydrolase. A novel enzyme.
The Western journal of medicine 1991;155(6):605-9.
1991: C J Chandler; D A Harrison; Buffington Tony; N A Santiago; Charles H Halsted
Functional specificity of jejunal brush-border pteroylpolyglutamate hydrolase in pig.
The American journal of physiology 1991;260(6 Pt 1):G865-72.
1991: Sheri Zidenberg-Cherr; K L Olin; J Villanueva; A Tang; stephen phinney; Charles H Halsted; Carl L Keen
Ethanol-induced changes in hepatic free radical defense mechanisms and fatty-acid composition in the miniature pig.
Hepatology (Baltimore, Md.) 1991;13(6):1185-92.
1991: C Heise; Satya Dandekar; P Kumar; R Duplantier; R M Donovan; Charles H Halsted
Human immunodeficiency virus infection of enterocytes and mononuclear cells in human jejunal mucosa.
Gastroenterology 1991;100(6):1521-7.
1990: Sheri Zidenberg-Cherr; Charles H Halsted; K L Olin; A M Reisenauer; Carl L Keen
The effect of chronic alcohol ingestion on free radical defense in the miniature pig.
The Journal of nutrition 1990;120(2):213-7.
1989: Charles H Halsted
The intestinal absorption of dietary folates in health and disease.
Journal of the American College of Nutrition 1989;8(6):650-8.
1989: C A Naughton; C J Chandler; R B Duplantier; Charles H Halsted
Folate absorption in alcoholic pigs: in vitro hydrolysis and transport at the intestinal brush border membrane.
The American journal of clinical nutrition 1989;50(6):1436-41.
1989: A M Reisenauer; Buffington Tony; Jesus A Villanueva; Charles H Halsted
Folate absorption in alcoholic pigs: in vivo intestinal perfusion studies.
The American journal of clinical nutrition 1989;50(6):1429-35.
1987: S Soberon; M P Pauley; R Duplantier; A Fan; Charles H Halsted
Metabolic effects of enteral formula feeding in alcoholic hepatitis.
Hepatology (Baltimore, Md.) 1987;7(6):1204-9.
1987: A M Reisenauer; Charles H Halsted
Human folate requirements.
The Journal of nutrition 1987;117(3):600-2.
1987: Charles H Halsted; C Heise
Ethanol and vitamin metabolism.
Pharmacology & therapeutics 1987;34(3):453-64.
1986: T T Wang; C J Chandler; Charles H Halsted
Intracellular pteroylpolyglutamate hydrolase from human jejunal mucosa. Isolation and characterization.
The Journal of biological chemistry 1986;261(29):13551-5.
1986: A M Reisenauer; C J Chandler; Charles H Halsted
Folate binding and hydrolysis by pig intestinal brush-border membranes.
The American journal of physiology 1986;251(4 Pt 1):G481-6.
1986: Charles H Halsted; W H Beer; C J Chandler; K Ross; Bruce M Wolfe; L Bailey; JJ Cerda
Clinical studies of intestinal folate conjugases.
The Journal of laboratory and clinical medicine 1986;107(3):228-32.
1986: C J Chandler; T T Wang; Charles H Halsted
Pteroylpolyglutamate hydrolase from human jejunal brush borders. Purification and characterization.
The Journal of biological chemistry 1986;261(2):928-33.
1985: A M Reisenauer; Charles H Halsted; L R Jacobs; Bruce M Wolfe
Human intestinal folate conjugase: adaptation after jejunoileal bypass.
The American journal of clinical nutrition 1985;42(4):660-5.
1985: T T Wang; A M Reisenauer; Charles H Halsted
Comparison of folate conjugase activities in human, pig, rat and monkey intestine.
The Journal of nutrition 1985;115(6):814-9.
1985: W H Beer; A Fan; Charles H Halsted
Clinical and nutritional implications of radiation enteritis.
The American journal of clinical nutrition 1985;41(1):85-91.
1984: Lynn B Bailey; JJ Cerda; B S Bloch; M J Busby; L Vargas; C J Chandler; Charles H Halsted
Effect of age on poly- and monoglutamyl folacin absorption in human subjects.
The Journal of nutrition 1984;114(10):1770-6.
1983: Bruce M Wolfe; W H Beer; J T Hayashi; Charles H Halsted; R A Cannon; K L Cox
Experience with home parenteral nutrition.
American journal of surgery 1983;146(1):7-14.
1981: A M Reisenauer; Charles H Halsted
Human jejunal brush border folate conjugase. Characteristics and inhibition by salicylazosulfapyridine.
Biochimica et biophysica acta 1981;659(1):62-9.