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Perry Halushka

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Chemicals & Drugs

Anatomy

Blood Platelets

Living Beings

Rats

Physiology

Platelet Aggregation

Disorders

Septic Shock

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Co-Publications
Name
89
Cook, James
25
Tempel, George
19
Morinelli, Thomas
17
Knapp, Daniel
16
Colwell, John
12
Ashton, Sarah
11
Fan, Hongkuan
10
Oatis, John
10
Saussy, David
8
Teti, Giuseppe
7
Zingarelli, Basilia
7
Spicer, Kenneth M.
4
Mayfield, Ronald
4
Sagel, Julius
4
Ferlito, Marcella

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Publications

TOP 3
Halushka Perry V; Krug Edward L
Is the training of biomedical scientists at a crossroads?
Fan Hongkuan; Zingarelli Basilia; Harris Vashaunta; Tempel George E; Halushka Perry V; Cook James A
Lysophosphatidic acid inhibits bacterial endotoxin-induced pro-inflammatory response: potential anti-inflammatory signaling pathways.
Moussa Omar; Ashton Anthony W; Fraig Mostafa; Garrett-Mayer Elizabeth; Ghoneim Mohamed A; Halushka Perry V; Watson Dennis K
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.

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All Publications

2009: Halushka Perry V; Krug Edward L
Is the training of biomedical scientists at a crossroads?
Academic medicine : journal of the Association of American Medical Colleges 2009;84(4):421-3.
2008: Fan Hongkuan; Zingarelli Basilia; Harris Vashaunta; Tempel George E; Halushka Perry V; Cook James A
Lysophosphatidic acid inhibits bacterial endotoxin-induced pro-inflammatory response: potential anti-inflammatory signaling pathways.
Molecular medicine (Cambridge, Mass.) 2008;14(7-8):422-8.
2008: Moussa Omar; Ashton Anthony W; Fraig Mostafa; Garrett-Mayer Elizabeth; Ghoneim Mohamed A; Halushka Perry V; Watson Dennis K
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
Cancer research 2008;68(11):4097-104.
2008: Moussa O; Riker J M; Klein J; Fraig M; Halushka P V; Watson D K
Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents.
Oncogene 2008;27(1):55-62.
2008: Basher Fahmin; Fan Hongkuan; Zingarelli Basilia; Borg Keith T; Luttrell Lou M; Tempel George E; Halushka Perry V; Cook James A
beta-Arrestin 2: a Negative Regulator of Inflammatory Responses in Polymorphonuclear Leukocytes.
International journal of clinical and experimental medicine 2008;1(1):32-41.
2007: Fan Hongkuan; Williams David L; Zingarelli Basilia; Breuel Kevin F; Teti Giuseppe; Tempel George E; Spicher Karsten; Boulay Guylain; Birnbaumer Lutz; Halushka Perry V; Cook James A
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Galpha(i) proteins.
Immunology 2007;122(1):116-23.
2007: Fan Hongkuan; Luttrell Louis M; Tempel George E; Senn Joseph J; Halushka Perry V; Cook James A
Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.
Molecular immunology 2007;44(12):3092-9.
2006: Fan Hongkuan; Williams David L; Zingarelli Basilia; Breuel Kevin F; Teti Giuseppe; Tempel George E; Spicher Karsten; Boulay Guylain; Birnbaumer Lutz; Halushka Perry V; Cook James A
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Galphai proteins.
Biochimica et biophysica acta 2006;1763(10):1051-8.
2006: Peck Octavia M; Zingarelli Basilia; Fan Hongkuan; Teti Giuseppe; Tempel George; Halushka Perry V; Cook James A
The phosphatidylinositol 3 kinase pathway regulates tolerance to lipopolysaccharide and priming responses to Staphylococcus aureus and lipopolysaccharide.
Shock (Augusta, Ga.) 2006;26(1):31-6.
2006: Halushka Marc K; Halushka Perry V
Toward individualized analgesic therapy: functional cyclooxygenase 1 and 2 haplotypes.
Clinical pharmacology and therapeutics 2006;79(5):404-6.
2006: Fan Hongkuan; Williams David L; Breuel Kevin F; Zingarelli Basilia; Teti Giuseppe; Tempel George E; Halushka Perry V; Cook James A
Gi proteins regulate lipopolysaccharide and Staphylococcus aureus induced cytokine production but not (1--> 3)-beta-D-glucan induced cytokine suppression.
Frontiers in bioscience : a journal and virtual library 2006;11():2264-74.
2005: Moussa Omar; Yordy John S; Abol-Enein Hassan; Sinha Debajyoti; Bissada Nabil K; Halushka Perry V; Ghoneim Mohamed A; Watson Dennis K
Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer.
Cancer research 2005;65(24):11581-7.
2005: Fan Hongkuan; Zingarelli Basilia; Peck Octavia M; Teti Giuseppe; Tempel George E; Halushka Perry V; Spicher Karsten; Boulay Guylain; Birnbaumer Lutz; Cook James A
Lipopolysaccharide- and gram-positive bacteria-induced cellular inflammatory responses: role of heterotrimeric Galpha(i) proteins.
American journal of physiology. Cell physiology 2005;289(2):C293-301.
2005: Ajayi A A L; Halushka P V
Castration reduces platelet thromboxane A2 receptor density and aggregability.
QJM : monthly journal of the Association of Physicians 2005;98(5):349-56.
2005: Malcolm Robert; LaRowe Steven; Cochran Kristi; Moak Darlene; Herron Janice; Brady Kathleen; Hedden Sarra; Woolson Robert; Halushka Perry
A controlled trial of amlodipine for cocaine dependence: a negative report.
Journal of substance abuse treatment 2005;28(2):197-204.
2004: Fan Hongkuan; Peck Octavia M; Tempel George E; Halushka Perry V; Cook James A
Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation.
Shock (Augusta, Ga.) 2004;22(1):57-62.
2004: Peck Octavia M; Fan Hongkuan; Tempel George E; Teti Giuseppe; Halushka Perry V; Cook James A
Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma.
Shock (Augusta, Ga.) 2004;21(3):254-60.
2003: Qiao Na; Reynaud Denis; Demin Peter; Halushka Perry V; Pace-Asciak Cecil R
The thromboxane receptor antagonist PBT-3, a hepoxilin stable analog, selectively antagonizes the TPalpha isoform in transfected COS-7 cells.
The Journal of pharmacology and experimental therapeutics 2003;307(3):1142-7.
2003: Taylor Dawne M; Halushka Perry V; Meier G Patrick
Hydrogen bond interactions of a series of N-substituted TXA2 receptor antagonists.
European journal of medicinal chemistry 2003;38(11-12):1015-24.
2003: Guyton Kelly; Zingarelli Basilia; Ashton Sarah; Teti Giuseppi; Tempel George; Reilly Chris; Gilkeson Gary; Halushka Perry; Cook James
Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli.
Shock (Augusta, Ga.) 2003;20(1):56-62.
2003: Fan Hongkuan; Teti Giuseppe; Ashton Sarah; Guyton Kelly; Tempel George E; Halushka Perry V; Cook James A
Involvement of G(i) proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus.
Cytokine 2003;22(5):126-33.
2003: Halushka Marc K; Walker Linda P; Halushka Perry V
Genetic variation in cyclooxygenase 1: effects on response to aspirin.
Clinical pharmacology and therapeutics 2003;73(1):122-30.
2003: Gale Donna D; Hofer Peter; Spina Domenico; Seeds Esther A; Banner Katherine H; Harrison Selina; Douglas Gary; Matsumoto Tatsui; Page Clive P; Wong Richard H; Jordan Stephan; Smith Forrest; Banik Nandini; Halushka Perry V; Cavalla David; Rotshteyn Yakov; Kyle Donald J; Burch Ronald M; Chasin Mark
Pharmacology of a new cyclic nucleotide phosphodiesterase type 4 inhibitor, V11294.
Pulmonary pharmacology & therapeutics 2003;16(2):97-104.
2002: Malcolm Robert; Liao Jason; Michel Melissa; Cochran Kristina; Pye Wesley; Yeager Derik; Halushka Perry V
Amlodipine reduces blood pressure and headache frequency in cocaine-dependent outpatients.
Journal of psychoactive drugs 2002;34(4):415-9.
2002: Halushka Marc K; Halushka Perry V
Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2?
Circulation 2002;105(14):1620-2.
2002: Ferlito Marcella; Romanenko Olga G; Guyton Kelly; Ashton Sarah; Squadrito Francesco; Halushka Perry V; Cook James A
Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production.
Journal of endotoxin research 2002;8(6):427-35.
2001: Tempel G E; Brown A N; Morinelli T A; Halushka P V; Cook J A
Changes in vascular responsiveness to a thromboxane mimetic in endotoxin tolerance.
Shock (Augusta, Ga.) 2001;16(5):389-92.
2001: Ferlito M; Romanenko O G; Ashton S; Squadrito F; Halushka P V; Cook J A
Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production.
Journal of leukocyte biology 2001;70(5):821-9.
2001: Walle T; Walle U K; Halushka P V
Carbon dioxide is the major metabolite of quercetin in humans.
The Journal of nutrition 2001;131(10):2648-52.
2001: Minshall R D; Pavcnik D; Halushka P V; Hermsmeyer K
Progesterone regulation of vascular thromboxane A(2) receptors in rhesus monkeys.
American journal of physiology. Heart and circulatory physiology 2001;281(4):H1498-507.
2001: Guyton K; Bond R; Reilly C; Gilkeson G; Halushka P; Cook J
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Journal of leukocyte biology 2001;69(4):631-8.
2001: Ferlito M; Squadrito F; Halushka P V; Cook J A
Signal transduction events in Chinese hamster ovary cells expressing human CD14; effect of endotoxin desensitization.
Shock (Augusta, Ga.) 2001;15(4):291-6.
2001: Reilly C M; Oates J C; Sudian J; Crosby M B; Halushka P V; Gilkeson G S
Prostaglandin J(2) inhibition of mesangial cell iNOS expression.
Clinical immunology (Orlando, Fla.) 2001;98(3):337-45.
2001: Walle T; Otake Y; Brubaker J A; Walle U K; Halushka P V
Disposition and metabolism of the flavonoid chrysin in normal volunteers.
British journal of clinical pharmacology 2001;51(2):143-6.
2000: Fernando L P; Fernando A N; Ferlito M; Halushka P V; Cook J A
Suppression of Cox-2 and TNF-alpha mRNA in endotoxin tolerance: effect of cycloheximide, antinomycin D, and okadaic acid.
Shock (Augusta, Ga.) 2000;14(2):128-33.
2000: Halushka P V
Thromboxane A(2) receptors: where have you gone?
Prostaglandins & other lipid mediators 2000;60(4-6):175-89.
2000: Reilly C M; Oates J C; Cook J A; Morrow J D; Halushka P V; Gilkeson G S
Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1498-504.
1999: Becker K P; Garnovskaya M; Gettys T; Halushka P V
Coupling of thromboxane A2 receptor isoforms to Galpha13: effects on ligand binding and signalling.
Biochimica et biophysica acta 1999;1450(3):288-96.
1999: Fernando L P; Makhlouf M; Fernando A N; Ashton S; Halushka P V; Cook J A
Tolerance to LPS decreases macrophage G protein content.
Shock (Augusta, Ga.) 1999;11(5):330-5.
1998: Pawate S; Schey K L; Meier G P; Ullian M E; Mais D E; Halushka P V
Expression, characterization, and purification of C-terminally hexahistidine-tagged thromboxane A2 receptors.
The Journal of biological chemistry 1998;273(35):22753-60.
1998: Becker K P; Ullian M; Halushka P V
Cloning and characterization of an endogenous COS-7 cell thromboxane A2 receptor.
Biochimica et biophysica acta 1998;1403(1):109-14.
1998: Durando M; Fernando L; Ashton S; Halushka P; Cook J
Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthase activity.
Shock (Augusta, Ga.) 1998;9(5):359-63.
1998: Makhlouf M A; Fernando L P; Gettys T W; Halushka P V; Cook J A
Increased prostacyclin and PGE2 stimulated cAMP production by macrophages from endotoxin-tolerant rats.
The American journal of physiology 1998;274(5 Pt 1):C1238-44.
1998: Wang G R; Zhu Y; Halushka P V; Lincoln T M; Mendelsohn M E
Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):4888-93.
1998: Makhlouf M; Zingarelli B; Halushka P V; Cook J A
Endotoxin tolerance alters macrophage membrane regulatory G proteins.
Progress in clinical and biological research 1998;397():217-26.
1997: Higashiura K; Mathur R S; Halushka P V
Gender-related differences in androgen regulation of thromboxane A2 receptors in rat aortic smooth-muscle cells.
Journal of cardiovascular pharmacology 1997;29(3):311-5.
1997: Brothers T E; Robison J G; Elliott B M; Boggs J M; Halushka P V
Thromboxane A2 receptor density increases during chronic exposure to thromboxane A2 receptor antagonists after porcine carotid bypass.
Cardiovascular surgery (London, England) 1997;5(1):92-8.
1997: Schrör K; Davis-Bruno K; Halushka P V
Modification on ligand binding to TXA2/PGH2 receptors by diethylpyrocarbonate.
Advances in experimental medicine and biology 1997;400A():235-40.
1996: Higashiura K; Blaney B; Morgan E; Mathur R S; Halushka P V
Inhibition of testosterone 5 alpha-reductase: evidence for tissue-specific regulation of thromboxane A2 receptors.
The Journal of pharmacology and experimental therapeutics 1996;279(3):1386-91.
1996: Makhlouf M; Ashton S H; Hildebrandt J; Mehta N; Gettys T W; Halushka P V; Cook J A
Alterations in macrophage G proteins are associated with endotoxin tolerance.
Biochimica et biophysica acta 1996;1312(2):163-8.
1996: Allan C J; Higashiura K; Martin M; Morinelli T A; Kurtz D T; Geoffroy O; Meier G P; Gettys T W; Halushka P V
Characterization of the cloned HEL cell thromboxane A2 receptor: evidence that the affinity state can be altered by G alpha 13 and G alpha q.
The Journal of pharmacology and experimental therapeutics 1996;277(2):1132-9.
1996: Wagner R S; Halushka P V; Cook J A
Activation of thromboxane A2 receptors alters lipopolysaccharide-induced adherence of THP-1 cells.
Shock (Augusta, Ga.) 1996;5(1):41-6.
1996: Paul R V; Saxenhofer H; Wackym P S; Halushka P V
Stimulation of rat mesangial cell thromboxane A2 receptors inhibits particulate but not soluble guanylyl cyclase.
The American journal of physiology 1996;270(1 Pt 2):F31-8.
1996: Zucker T P; Higashiura K; Mathur R S; Halushka P V
Androstenedione increases thromboxane A2 receptors in human erythroleukemia cells.
Life sciences 1996;58(8):683-90.
1995: Halushka P V; Allan C J; Davis-Bruno K L
Thromboxane A2 receptors.
Journal of lipid mediators and cell signalling 1995;12(2-3):361-78.
1995: Ajayi A A; Mathur R; Halushka P V
Testosterone increases human platelet thromboxane A2 receptor density and aggregation responses.
Circulation 1995;91(11):2742-7.
1995: Schrör K; Davis-Bruno K; Halushka P V
Inhibition of ligand binding to thromboxane A2/prostaglandin H2 receptors by diethylpyrocarbonate. Protection by receptor ligands and reversal by hydroxylamine.
Biochemical pharmacology 1995;49(7):921-7.
1995: Matsuda K; Mathur R S; Ullian M E; Halushka P V
Sex steroid regulation of thromboxane A2 receptors in cultured rat aortic smooth muscle cells.
Prostaglandins 1995;49(3):183-96.
1995: Zingarelli B; Halushka P V; Caputi A P; Cook J A
Increased nitric oxide synthesis during the development of endotoxin tolerance.
Shock (Augusta, Ga.) 1995;3(2):102-8.
1995: Zingarelli B; Chen H; Caputi A P; Halushka P V; Cook J A
Reorientation of macrophage mediator production in endotoxin tolerance.
Progress in clinical and biological research 1995;392():529-37.
1995: Ajayi A A; Matsuda K; Schrör K; Masuda A; Mathur R; Halushka P V
Androgen regulation of thromboxane A2 receptors.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():251-3.
1995: Zucker T P; Grosser T; Morinelli T; Halushka P V; Sachinidis A; Vetter H; Schrör K
Potentiation of PDGF-induced growth responses in coronary artery smooth muscle cells by thromboxane.
Agents and actions. Supplements 1995;45():53-8.
1995: Halushka P V; Matsuda K; Masuda A; Ruff A; Morinelli T A; Mathur R S
Testosterone regulation of platelet and vascular thromboxane A2 receptors.
Agents and actions. Supplements 1995;45():19-26.
1994: Geisel J; Cook J A; Ashton S H; Wise W C; Halushka P V
Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2.
The American journal of physiology 1994;267(4 Pt 1):C1067-72.
1994: Matsuda K; Ruff A; Morinelli T A; Mathur R S; Halushka P V
Testosterone increases thromboxane A2 receptor density and responsiveness in rat aortas and platelets.
The American journal of physiology 1994;267(3 Pt 2):H887-93.
1994: Yin K; Halushka P V; Yan Y T; Wong P Y
Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F-series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets.
The Journal of pharmacology and experimental therapeutics 1994;270(3):1192-6.
1994: Allan C J; Halushka P V
Characterization of human peripheral blood monocyte thromboxane A2 receptors.
The Journal of pharmacology and experimental therapeutics 1994;270(2):446-52.
1994: Buzzard C J; Pfister S L; Halushka P V; Campbell W B
Decrease in vascular TxA2 receptors in a subgroup of rabbits unresponsive to a TxA2 mimetic.
The American journal of physiology 1994;266(6 Pt 2):H2320-6.
1994: Chen H; Halushka P V; Cook J A
Endotoxin tolerance: effects on lethality and macrophage thromboxane (B2) and interleukin 6 production.
Shock (Augusta, Ga.) 1994;1(5):366-71.
1994: Okwu A K; Mais D E; Halushka P V
Agonist-induced phosphorylation of human platelet TXA2/PGH2 receptors.
Biochimica et biophysica acta 1994;1221(1):83-8.
1994: Schrör K; Morinelli T A; Masuda A; Matsuda K; Mathur R S; Halushka P V
Testosterone treatment enhances thromboxane A2 mimetic induced coronary artery vasoconstriction in guinea pigs.
European journal of clinical investigation 1994;24 Suppl 1():50-2.
1994: Rinder C A; Halushka P V; Sens M A; Ploth D W
Thromboxane A2 receptor blockade improves renal function and histopathology in the post-obstructive kidney.
Kidney international 1994;45(1):185-92.
1994: Halushka P V; Masuda A; Matsuda K
The Gordon Wilson Lecture. Regulation of thromboxane A2 receptors by testosterone: implications for steroid abuse and cardiovascular disease.
Transactions of the American Clinical and Climatological Association 1994;105():95-103.
1993: Matsuda K; Mathur R S; Duzic E; Halushka P V
Androgen regulation of thromboxane A2/prostaglandin H2 receptor expression in human erythroleukemia cells.
The American journal of physiology 1993;265(6 Pt 1):E928-34.
1993: Liel N; Nathan I; Yermiyahu T; Zolotov Z; Lieberman J R; Dvilansky A; Halushka P V
Increased platelet thromboxane A2/prostaglandin H2 receptors in patients with pregnancy induced hypertension.
Thrombosis research 1993;70(3):205-10.
1993: Morinelli T A; Tempel G E; Jaffa A A; Silva R H; Naka M; Folger W; Halushka P V
Thromboxane A2/prostaglandin H2 receptors in streptozotocin-induced diabetes: effects of insulin therapy in the rat.
Prostaglandins 1993;45(5):427-38.
1993: Matera G; Cook J A; Geisel J; Ashton S H; Wise W C; Focá A; Berkowitz B A; Halushka P V
Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages.
Antimicrobial agents and chemotherapy 1993;37(3):393-7.
1993: Simmons T R; Cook J A; Moore J N; Halushka P V
Thromboxane A2 receptors in equine monocytes: identification of a new subclass of TXA2 receptors.
Journal of leukocyte biology 1993;53(2):173-8.
1993: Cook J A; Geisel J; Halushka P V; Reines H D
Prostaglandins, thromboxanes, leukotrienes, and cytochrome P-450 metabolites of arachidonic acid.
New horizons (Baltimore, Md.) 1993;1(1):60-9.
1992: Folger W H; Halushka P V; Wilcox C S; Guzman N J
Characterization of rat glomerular thromboxane A2 receptors: comparison to rat platelets.
European journal of pharmacology 1992;227(1):71-8.
1992: Coffee K A; Halushka P V; Ashton S H; Tempel G E; Wise W C; Cook J A
Endotoxin tolerance is associated with altered GTP-binding protein function.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(3):1008-13.
1992: Naka M; Mais D E; Morinelli T A; Hamanaka N; Oatis J E; Halushka P V
7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors.
The Journal of pharmacology and experimental therapeutics 1992;262(2):632-7.
1992: Okwu A K; Ullian M E; Halushka P V
Homologous desensitization of human platelet thromboxane A2/prostaglandin H2 receptors.
The Journal of pharmacology and experimental therapeutics 1992;262(1):238-45.
1991: Bernard G R; Reines H D; Halushka P V; Higgins S B; Metz C A; Swindell B B; Wright P E; Watts F L; Vrbanac J J
Prostacyclin and thromboxane A2 formation is increased in human sepsis syndrome. Effects of cyclooxygenase inhibition.
The American review of respiratory disease 1991;144(5):1095-101.
1991: Masuda A; Mathur R; Halushka P V
Testosterone increases thromboxane A2 receptors in cultured rat aortic smooth muscle cells.
Circulation research 1991;69(3):638-43.
1991: Geisel J; Cook J A; Coffee K A; Wise W C; Halushka P V
Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.
Biochimica et biophysica acta 1991;1085(1):15-20.
1991: Li E J; Cook J A; Wise W C; Jackson W T; Halushka P V
Effect of LTB4 receptor antagonists in endotoxic shock in the rat.
Circulatory shock 1991;34(4):385-92.
1991: Masuda A; Mais D E; Oatis J E; Halushka P V
Platelet and vascular thromboxane A2/prostaglandin H2 receptors. Evidence for different subclasses in the rat.
Biochemical pharmacology 1991;42(3):537-44.
1991: Mayeux P R; Morinelli T A; Williams T C; Hazard E S; Mais D E; Oatis J E; Baron D A; Halushka P V
Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets.
The Journal of biological chemistry 1991;266(21):13752-8.
1991: Li E J; Cook J A; Ashton S; Wise W C; Halushka P V
Effect of the LTD4 receptor antagonist LY203647 on endotoxic shock sequelae in the rat.
European journal of pharmacology 1991;199(2):221-5.
1991: Mais D E; Bowling N L; True T A; Naka M; Morinelli T A; Oatis J E; Hamanaka N; Halushka P V
Novel synthesis and biochemical properties of an [125I]-labeled photoaffinity probe for thromboxane A2/prostaglandin H2 receptors.
Journal of medicinal chemistry 1991;34(4):1511-4.
1991: Mayeux P R; Mais D E; Halushka P V
Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor.
European journal of pharmacology 1991;206(1):15-21.
1991: Coffee K A; Halushka P V; Wise W C; Tempel G E; Cook J A
Endotoxin tolerance differentially alters hemodynamic responses to a thromboxane A2 mimetic and phenylephrine.
Journal of cardiovascular pharmacology 1991;17(1):20-6.
1991: Moore J N; Cook J A; Henry M M; Jonsson H T; Spicer K M; Wise W C; Halushka P V
Effects of a linseed oil enriched diet on endotoxin-induced sequelae: differential in vitro and in vivo effects.
Eicosanoids 1991;4(1):47-55.
1991: Masuda A; Halushka P V
Thromboxane A2 receptors are influenced by cell density in cultured rat aortic smooth muscle cells.
Life sciences 1991;48(25):2391-5.
1991: Morinelli T A; Naka M; Masuda A; Oatis J E; Okwu A K; Mais D E; Saussy D L; Halushka P V
Characterization of thromboxane A2/prostaglandin H2 receptors of various tissues using a new radioiodinated thromboxane A2/prostaglandin H2 mimetic, I-BOP.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():331-7.
1991: Zellner J L; Cook J A; Reines H D; Smith E F; Kessler L D; Halushka P V
Effect of a LTD4 receptor antagonist in porcine septic shock.
Eicosanoids 1991;4(3):169-75.
1990: Sessa W C; Halushka P V; Okwu A; Nasjletti A
Characterization of the vascular thromboxane A2/prostaglandin endoperoxide receptor in rabbit aorta. Regulation by dexamethasone.
Circulation research 1990;67(6):1562-9.
1990: Cook J A; Li E J; Spicer K M; Wise W C; Halushka P V
Effect of leukotriene receptor antagonists on vascular permeability during endotoxic shock.
Circulatory shock 1990;32(3):209-18.
1990: Mais D E; Liel N; Halushka P V
Photoaffinity receptor antagonist for human platelet thromboxane A2/prostaglandin H2 receptors.
Biochemical pharmacology 1990;40(7):1457-61.
1990: Coffee K A; Halushka P V; Wise W C; Cook J A
Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance.
Biochimica et biophysica acta 1990;1035(2):201-5.
1990: Moore J N; Cook J A; Morris D D; Halushka P V; Wise W C
Endotoxin-induced procoagulant activity, eicosanoid synthesis, and tumor necrosis factor production by rat peritoneal macrophages: effect of endotoxin tolerance and glucan.
Circulatory shock 1990;31(3):281-95.
1990: Li E J; Cook J A; Spicer K M; Wise W C; Rokach J; Halushka P V
Resistance of essential fatty acid-deficient rats to endotoxin-induced increases in vascular permeability.
Circulatory shock 1990;31(2):159-70.
1990: Nishimiya T; Daniell H B; Webb J G; Oatis J; Walle T; Gaffney T E; Halushka P V
Chronic treatment with propranolol enhances the synthesis of prostaglandins E2 and I2 by the aorta of spontaneously hypertensive rats.
The Journal of pharmacology and experimental therapeutics 1990;253(1):207-13.
1990: Dorn G W; Liel N; Trask J L; Mais D E; Assey M E; Halushka P V
Increased platelet thromboxane A2/prostaglandin H2 receptors in patients with acute myocardial infarction.
Circulation 1990;81(1):212-8.
1990: Halushka P V; Morinelli T A; Mais D E
Radioligand binding assays for thromboxane A2/prostaglandin H2 receptors.
Methods in enzymology 1990;187():397-405.
1990: Morinelli T A; Mais D E; Oatis J E; Mayeux P R; Okwu A K; Masuda A; Knapp D R; Halushka P V
I-BOP, the most potent radiolabelled agonist for the TXA2/PGH2 receptor.
Advances in prostaglandin, thromboxane, and leukotriene research 1990;20():102-9.
1990: Morinelli T A; Mais D E; Oatis J E; Crumbley A J; Halushka P V
Characterization of thromboxane A2/prostaglandin H2 receptors in human vascular smooth muscle cells.
Life sciences 1990;46(24):1765-72.
1990: Zellner J L; Cook J A; Reines D H; Wise W C; Smith E F; Kessler L D; Halushka P V
Hemodynamic effects of leukotriene (LT) D4 and a LTD4 receptor antagonist in the pig.
Eicosanoids 1990;3(4):219-24.
1989: Morinelli T A; Oatis J E; Okwu A K; Mais D E; Mayeux P R; Masuda A; Knapp D R; Halushka P V
Characterization of an 125I-labeled thromboxane A2/prostaglandin H2 receptor agonist.
The Journal of pharmacology and experimental therapeutics 1989;251(2):557-62.
1989: Mayeux P R; Mais D E; Carr C; Halushka P V
Human erythroleukemia cells express functional thromboxane A2/prostaglandin H2 receptors.
The Journal of pharmacology and experimental therapeutics 1989;250(3):923-7.
1989: Heffner J E; Cook J A; Halushka P V
Human platelets modulate edema formation in isolated rabbit lungs.
The Journal of clinical investigation 1989;84(3):757-64.
1989: Ball H A; Cook J A; Spicer K M; Wise W C; Halushka P V
Essential fatty acid-deficient rats are resistant to oleic acid-induced pulmonary injury.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(2):811-6.
1989: Watt G H; Ashton S H; Cook J A; Wise W C; Halushka P V; Galbraith R M
Alterations in plasma levels and complexing of Gc (vitamin D-binding protein) in rats with endotoxic shock.
Circulatory shock 1989;28(3):279-91.
1989: Lee W M; Reines D; Watt G H; Cook J A; Wise W C; Halushka P V; Galbraith R M
Alterations in Gc levels and complexing in septic shock.
Circulatory shock 1989;28(3):249-55.
1989: Morinelli T A; Okwu A K; Mais D E; Halushka P V; John V; Chen C K; Fried J
Difluorothromboxane A2 and stereoisomers: stable derivatives of thromboxane A2 with differential effects on platelets and blood vessels.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5600-4.
1989: Mais D E; Yoakim C; Guindon Y; Gillard J W; Rokach J; Halushka P V
Photoaffinity labelling of the human platelet thromboxane A2/prostaglandin H2 receptor.
Biochimica et biophysica acta 1989;1012(2):184-90.
1989: Powers K; Fyfe D A; Taylor A B; Halushka P V; Crawford F A
Treatment of pulmonary vasospasm with prazosin after atrial septal defect closure in a child.
The Journal of thoracic and cardiovascular surgery 1989;97(5):802-4.
1989: Rogers T S; Halushka P V; Wise W C; Cook J A
Arachidonic acid turnover in peritoneal macrophages is altered in endotoxin-tolerant rats.
Biochimica et biophysica acta 1989;1001(2):169-75.
1989: Wise W C; Cook J A; Tempel G E; Reines H D; Halushka P V
The rat in sepsis and endotoxic shock.
Progress in clinical and biological research 1989;299():243-52.
1989: Halushka P V; Mais D E; Mayeux P R; Morinelli T A
Thromboxane, prostaglandin and leukotriene receptors.
Annual review of pharmacology and toxicology 1989;29():213-39.
1989: Halushka P V
Pharmacology of thromboxane A2 receptor antagonists.
Zeitschrift für Kardiologie 1989;78 Suppl 3():42-7.
1989: Mais D E; Halushka P V
Photoaffinity labelling of the human platelet thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor.
Progress in clinical and biological research 1989;301():303-7.
1989: Halushka P V; Mais D E; Morinelli T A
Thromboxane and prostacyclin receptors.
Progress in clinical and biological research 1989;301():21-8.
1989: Mais D E; Halushka P V
Photoaffinity labelling and isoelectric focusing of the human platelet thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():168-71.
1989: Tempel G E; Strong J W; Wise W C; Cook J A; Smith E F; Halushka P V
The role of eicosanoids in mediating blood flow alterations in endotoxin shock.
Progress in clinical and biological research 1989;299():33-42.
1988: Liel N; Mais D E; Halushka P V
Desensitization of platelet thromboxane A2/prostaglandin H2 receptors by the mimetic U46619.
The Journal of pharmacology and experimental therapeutics 1988;247(3):1133-8.
1988: Mayeux P R; Morton H E; Gillard J; Lord A; Morinelli T A; Boehm A; Mais D E; Halushka P V
The affinities of prostaglandin H2 and thromboxane A2 for their receptor are similar in washed human platelets.
Biochemical and biophysical research communications 1988;157(2):733-9.
1988: Matera G; Cook J A; Hennigar R A; Tempel G E; Wise W C; Oglesby T D; Halushka P V
Beneficial effects of a 5-lipoxygenase inhibitor in endotoxic shock in the rat.
The Journal of pharmacology and experimental therapeutics 1988;247(1):363-71.
1988: Katz S A; Venkatachalam M; Crouch R K; Heffner J E; Halushka P V; Wise W C; Cook J A
Catalase pretreatment attenuates oleic acid-induced edema in isolated rabbit lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1301-6.
1988: Heffner J E; Katz S A; Halushka P V; Cook J A
Human platelets attenuate oxidant injury in isolated rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1258-66.
1988: Ball H A; Cook J A; Spicer K M; Hsu C Y; Halushka P V
Oleic acid-induced pulmonary injury in rats: potential role of sulfidopeptide leukotrienes.
Circulatory shock 1988;26(1):59-70.
1988: Mais D E; DeHoll D; Sightler H; Halushka P V
Different pharmacologic activities for 13-azapinane thromboxane A2 analogs in platelets and blood vessels.
European journal of pharmacology 1988;148(3):309-15.
1988: Saussy D L; Mais D E; Baron D A; Pepkowitz S H; Halushka P V
Subcellular localization of a thromboxane A2/prostaglandin H2 receptor antagonist binding site in human platelets.
Biochemical pharmacology 1988;37(4):647-54.
1988: Hsu C Y; Halushka P V; Spicer K M; Hogan E L; Martin H F
Temporal profile of thromboxane-prostacyclin imbalance in experimental spinal cord injury.
Journal of the neurological sciences 1988;83(1):55-62.
1988: Halushka P V; Boehm A; Mais D E
Polymyxin B increases TXA2/PGH2 agonist and antagonist affinities in human platelet membranes.
Eicosanoids 1988;1(1):41-4.
1987: Liel N; Mais D E; Halushka P V
Binding of a thromboxane A2/prostaglandin H2 agonist [3H]U46619 to washed human platelets.
Prostaglandins 1987;33(6):789-97.
1987: Dorn G W; Sens D; Chaikhouni A; Mais D; Halushka P V
Cultured human vascular smooth muscle cells with functional thromboxane A2 receptors: measurement of U46619-induced 45calcium efflux.
Circulation research 1987;60(6):952-6.
1987: Dorn G W; Burch R M; Kochel P J; Mais D E; Halushka P V
Decrease in agonist affinity for human platelet thromboxane A2/prostaglandin H2 receptors induced by a platelet-derived supernatant.
Biochemical pharmacology 1987;36(12):1913-7.
1987: Halushka P V; Kochel P J; Mais D E
Binding of thromboxane A2/prostaglandin H2 agonists to human platelets.
British journal of pharmacology 1987;91(1):223-7.
1987: Smith E F; Wise W C; Halushka P V; Cook J A
Macrophage eicosanoid formation is stimulated by platelet arachidonic acid and prostaglandin endoperoxide transfer.
Biochimica et biophysica acta 1987;923(3):355-61.
1987: Fuhrman T M; Hollon M F; Reines H D; Olanoff L S; Halushka P V
Beneficial effects of ibuprofen in oleic acid induced lung injury.
The Journal of surgical research 1987;42(3):284-9.
1987: Hubbard H L; Eller T D; Mais D E; Halushka P V; Baker R H; Blair I A; Vrbanac J J; Knapp D R
Extraction of thromboxane B2 from urine using an immobilized antibody column for subsequent analysis by gas chromatography-mass spectrometry.
Prostaglandins 1987;33(2):149-60.
1987: Halushka P V; Lefer A M
Thromboxane A2 in health and disease.
Federation proceedings 1987;46(1):131-2.
1987: Halushka P V; Mais D E; Saussy D L
Platelet and vascular smooth muscle thromboxane A2/prostaglandin H2 receptors.
Federation proceedings 1987;46(1):149-53.
1987: Katz S A; Halushka P V; Wise W C; Cook J A
Oleic acid induces pulmonary injury independent of eicosanoids in the isolated, perfused rabbit lung.
Circulatory shock 1987;22(3):221-30.
1987: Etemadi A R; Tempel G E; Farah B A; Wise W C; Halushka P V; Cook J A
Beneficial effects of a leukotriene antagonist on endotoxin-induced acute hemodynamic alterations.
Circulatory shock 1987;22(1):55-63.
1986: Halushka P V; Mais D E; Garvin M
Binding of a thromboxane A2/prostaglandin H2 receptor antagonist to guinea-pig platelets.
European journal of pharmacology 1986;131(1):49-54.
1986: Mais D E; Burch R M; Oatis J E; Knapp D R; Halushka P V
Photoaffinity labelling of a thromboxane A2/prostaglandin H2 antagonist binding site in human platelets.
Biochemical and biophysical research communications 1986;140(1):128-33.
1986: Chaikhouni A; Crawford F A; Kochel P J; Olanoff L S; Halushka P V
Human internal mammary artery produces more prostacyclin than saphenous vein.
The Journal of thoracic and cardiovascular surgery 1986;92(1):88-91.
1986: Hsu C Y; Halushka P V; Hogan E L; Cox R D
Increased thromboxane level in experimental spinal cord injury.
Journal of the neurological sciences 1986;74(2-3):289-96.
1986: Tempel G E; Cook J A; Wise W C; Halushka P V; Corral D
Improvement in organ blood flow by inhibition of thromboxane synthetase during experimental endotoxic shock in the rat.
Journal of cardiovascular pharmacology 1986;8(3):514-9.
1986: Rogers T S; Halushka P V; Wise W C; Cook J A
Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance.
Prostaglandins 1986;31(4):639-50.
1986: Chen S T; Hsu C Y; Hogan E L; Halushka P V; Linet O I; Yatsu F M
Thromboxane, prostacyclin, and leukotrienes in cerebral ischemia.
Neurology 1986;36(4):466-70.
1986: Saussy D L; Mais D E; Burch R M; Halushka P V
Identification of a putative thromboxane A2/prostaglandin H2 receptor in human platelet membranes.
The Journal of biological chemistry 1986;261(7):3025-9.
1986: Armstrong J; Tempel G E; Cook J A; Wise W C; Halushka P V
The effects of alpha adrenergic blockade on arachidonic acid metabolism and shock sequelae in endotoxemia.
Circulatory shock 1986;20(2):151-9.
1986: Ball H A; Cook J A; Wise W C; Halushka P V
Role of thromboxane, prostaglandins and leukotrienes in endotoxic and septic shock.
Intensive care medicine 1986;12(3):116-26.
1985: Halushka P V; Mayfield R; Colwell J A
Insulin and arachidonic acid metabolism in diabetes mellitus.
Metabolism: clinical and experimental 1985;34(12 Suppl 1):32-6.
1985: Mais D E; Burch R M; Saussy D L; Kochel P J; Halushka P V
Binding of a thromboxane A2/prostaglandin H2 receptor antagonist to washed human platelets.
The Journal of pharmacology and experimental therapeutics 1985;235(3):729-34.
1985: Saussy D L; Mais D E; Knapp D R; Halushka P V
Thromboxane A2 and prostaglandin endoperoxide receptors in platelets and vascular smooth muscle.
Circulation 1985;72(6):1202-7.
1985: Mayfield R K; Halushka P V; Wohltmann H J; Lopes-Virella M; Chambers J K; Loadholt C B; Colwell J A
Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients.
Diabetes 1985;34(11):1127-33.
1985: Burch R M; Mais D E; Pepkowitz S H; Halushka P V
Hydrodynamic properties of a thromboxane A2/prostaglandin H2 antagonist binding site solubilized from human platelets.
Biochemical and biophysical research communications 1985;132(3):961-8.
1985: Burch R M; Mais D E; Saussy D L; Halushka P V
Solubilization of a thromboxane A2/prostaglandin H2 antagonist binding site from human platelets.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(21):7434-8.
1985: Cook J A; Wise W C; Halushka P V
Protective effect of a selective leukotriene antagonist in endotoxemia in the rat.
The Journal of pharmacology and experimental therapeutics 1985;235(2):470-4.
1985: Baron D A; Burch R M; Halushka P V; Spicer S S
Blockade of colchicine-induced inhibition of vasopressin-stimulated osmotic water flow: failure to influence microtubule formation.
The American journal of physiology 1985;249(4 Pt 2):F464-9.
1985: Mais D E; Kochel P J; Saussy D L; Halushka P V
Binding of an 125I-labeled thromboxane A2/prostaglandin H2 receptor antagonist to washed canine platelets.
Molecular pharmacology 1985;28(2):163-9.
1985: Hsu C Y; Halushka P V; Hogan E L; Banik N L; Lee W A; Perot P L
Alteration of thromboxane and prostacyclin levels in experimental spinal cord injury.
Neurology 1985;35(7):1003-9.
1985: Dorn G W; Halushka P V
Thromboxane synthetase inhibitors, thromboxane receptor antagonists, and aspirin in cardiovascular disease.
Rational drug therapy 1985;19(7):1-7.
1985: Olanoff L S; Cook J A; Halushka P V
Sulindac does not preserve renal prostacyclin synthesis during endotoxemia.
Prostaglandins 1985;29(6):1031-7.
1985: Halushka P V; Reines H D; Barrow S E; Blair I A; Dollery C T; Rambo W; Cook J A; Wise W C
Elevated plasma 6-keto-prostaglandin F1 alpha in patients in septic shock.
Critical care medicine 1985;13(6):451-3.
1985: Mais D E; Saussy D L; Chaikhouni A; Kochel P J; Knapp D R; Hamanaka N; Halushka P V
Pharmacologic characterization of human and canine thromboxane A2/prostaglandin H2 receptors in platelets and blood vessels: evidence for different receptors.
The Journal of pharmacology and experimental therapeutics 1985;233(2):418-24.
1985: Mais D E; Dunlap C; Hamanaka N; Halushka P V
Further studies on the effects of epimers of thromboxane A2 antagonists on platelets and veins.
European journal of pharmacology 1985;111(1):125-8.
1985: Reines H D; Halushka P V; Cook J A; Loadholt C B
Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock.
Surgery, gynecology & obstetrics 1985;160(4):320-2.
1985: Reines H D; Halushka P V; Olanoff L S; Hunt P S
Dazoxiben in human sepsis and adult respiratory distress syndrome.
Clinical pharmacology and therapeutics 1985;37(4):391-5.
1985: Halushka P V; MacDermot J; Knapp D R; Eller T; Saussy D L; Mais D; Blair I A; Dollery C T
A novel approach for the study of thromboxane A2 and prostaglandin H2 receptors using an 125I-labeled ligand.
Biochemical pharmacology 1985;34(8):1165-70.
1985: Olanoff L S; Cook J A; Eller T; Knapp D R; Halushka P V
Protective effects of trans-13-APT, a thromboxane receptor antagonist, in endotoxemia.
Journal of cardiovascular pharmacology 1985;7(1):114-20.
1985: Cook J A; Wise W C; Tempel G E; Halushka P V
Exchange transfusions in rats with a perfluorated blood substitute: effect on thromboxane B2 levels during endotoxemia.
Circulatory shock 1985;15(3):193-204.
1985: Margolius H S; Halushka P V; Chao J; Miller D H; Cuthbert A W; Spayne J A
Studies of the kallikrein-kinin system and prostaglandins in epithelial ion transport.
Society of General Physiologists series 1985;39():121-33.
1985: Wise W C; Halushka P V; Knapp R G; Cook J A
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.
Circulatory shock 1985;17(1):59-71.
1985: Smith E F; Tempel G E; Wise W C; Halushka P V; Cook J A
Experimental endotoxemia in the rat: efficacy of prostacyclin or the prostacyclin analog iloprost.
Circulatory shock 1985;16(1):1-7.
1984: Burch R M; Halushka P V
ADH or theophylline-induced changes in intracellular free and membrane-bound calcium.
The American journal of physiology 1984;247(6 Pt 2):F939-45.
1984: Cuthbert A W; Halushka P V; Kessel D; Margolius H S; Wise W C
Kinin effects on chloride secretion do not require eicosanoid synthesis.
British journal of pharmacology 1984;83(2):549-54.
1984: Cuthbert A W; Halushka P V; Margolius H S; Spayne J A
Mediators of the secretory response to kinins.
British journal of pharmacology 1984;82(3):597-607.
1984: Cuthbert A W; Halushka P V; Margolius H S; Spayne J A
Role of calcium ions in kinin-induced chloride secretion.
British journal of pharmacology 1984;82(3):587-95.
1984: Olanoff L S; Reines H D; Spicer K M; Halushka P V
Effects of oleic acid on pulmonary capillary leak and thromboxanes.
The Journal of surgical research 1984;36(6):597-605.
1984: Burch R M; Halushka P V
Alterations in extracellular calcium concentration differentially influence prostaglandin and thromboxane synthesis in epithelial cells from the toad urinary bladder.
Archives of biochemistry and biophysics 1984;229(1):90-7.
1984: Cook J A; Wise W C; Butler R R; Reines H D; Rambo W; Halushka P V
The potential role of thromboxane and prostacyclin in endotoxic and septic shock.
The American journal of emergency medicine 1984;2(1):28-37.
1984: Rogers T S; Smith E F; Wise W C; Halushka P V; Cook J A
Interaction of eicosanoids and macrophages during inflammatory responses.
Survey of immunologic research 1984;3(2-3):161-4.
1983: Colwell J A; Winocour P D; Lopes-Virella M; Halushka P V
New concepts about the pathogenesis of atherosclerosis in diabetes mellitus.
The American journal of medicine 1983;75(5B):67-80.
1983: Burch R M; Wise W C; Halushka P V
Prostaglandin-independent inhibition of calcium transport by nonsteroidal anti-inflammatory drugs: differential effects of carboxylic acids and piroxicam.
The Journal of pharmacology and experimental therapeutics 1983;227(1):84-91.
1983: Chong K P; Burch R M; Black M; Maloney E; Jollow D J; Halushka P V
Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content.
Prostaglandins 1983;26(3):397-408.
1983: Burch R M; Halushka P V
Verapamil inhibition of vasopressin-stimulated water flow: possible role of intracellular calcium.
The Journal of pharmacology and experimental therapeutics 1983;226(3):701-5.
1983: Halushka P V; Wise W C; Cook J A
Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism.
The American journal of medicine 1983;74(6A):91-6.
1983: Colwell J A; Winocour P D; Halushka P V
Do platelets have anything to do with diabetic microvascular disease?
Diabetes 1983;32 Suppl 2():14-9.
1983: Anderegg K; Anzeveno P; Cook J A; Halushka P V; McCarthy J; Wagner E; Wise W C
Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat.
British journal of pharmacology 1983;78(4):725-32.
1983: Butler R R; Wise W C; Halushka P V; Cook J A
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.
The Journal of pharmacology and experimental therapeutics 1983;225(1):94-101.
1983: Newman W H; Frankis M B; Halushka P V
Increased myocardial release of prostacyclin in dogs with heart failure.
Journal of cardiovascular pharmacology 1983;5(2):194-201.
1983: Hohn A R; Riopel D A; Keil J E; Loadholt C B; Margolius H S; Halushka P V; Privitera P J; Webb J G; Medley E S; Schuman S H; Rubin M I; Pantell R H; Braunstein M L
Childhood familial and racial differences in physiologic and biochemical factors related to hypertension.
Hypertension 1983;5(1):56-70.
1983: Burch R M; Halushka P V
45Ca fluxes in isolated toad bladder epithelial cells: effects of agents which alter water or sodium transport.
The Journal of pharmacology and experimental therapeutics 1983;224(1):108-17.
1983: Wise W C; Cook J A; Halushka P V
Arachidonic acid metabolism in endotoxin tolerance.
Advances in shock research 1983;10():131-42.
1983: Halushka P V; Dollery C T; MacDermot J
Thromboxane and prostacyclin in disease: a review.
The Quarterly journal of medicine 1983;52(208):461-70.
1983: Halushka P V; Cook J A; Wise W C
Beneficial effects of UK 37248, a thromboxane synthetase inhibitor, in experimental endotoxic shock in the rat.
British journal of clinical pharmacology 1983;15 Suppl 1():133S-139S.
1982: Burch R M; Halushka P V
Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells.
The American journal of physiology 1982;243(6):F593-7.
1982: Kelley V E; Izui S; Halushka P V
Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus.
Clinical immunology and immunopathology 1982;25(2):223-31.
1982: Wilson T W; Loadholt C B; Privitera P J; Halushka P V
Furosemide increases urine 6-keto-prostaglandin F1 alpha. Relation to natriuresis, vasodilation, and renin release.
Hypertension 1982;4(5):634-41.
1982: Reines H D; Halushka P V; Cook J A; Wise W C; Rambo W
Plasma thromboxane concentrations are raised in patients dying with septic shock.
Lancet 1982;2(8291):174-5.
1982: Colwell J A; Halushka P V
Platelets, prostaglandins, and coagulation in diabetes mellitus.
The Mount Sinai journal of medicine, New York 1982;49(3):215-22.
1982: Burch R M; Halushka P V
Inhibition of prostaglandin synthesis antagonizes the colchicine-induced reduction of vasopressin-stimulated water flow in the toad urinary bladder.
Molecular pharmacology 1982;21(1):142-9.
1982: Cook J A; Halushka P V; Wise W C
Modulation of macrophage arachidonic acid metabolism: potential role in the susceptibility of rats to endotoxic shock.
Circulatory shock 1982;9(6):605-17.
1982: Tempel G E; Cook J A; Wise W C; Halushka P V
The improvement in endotoxin-induced redistribution of organ blood flow by inhibition of thromboxane and prostaglandin synthesis.
Advances in shock research 1982;7():209-18.
1982: Butler R R; Wise W C; Halushka P V; Cook J A
Thromboxane and prostacyclin production during septic shock.
Advances in shock research 1982;7():133-45.
1981: Russel M P; Privitera P J; Walle T; Peet N P; Halushka P V; Gaffney T E
Cardiovascular effects of a 4'-methylthio analog of propranolol.
The Journal of pharmacology and experimental therapeutics 1981;219(3):685-90.
1981: Cook J A; Wise W C; Halushka P V
Thromboxane A2 and prostacyclin production by lipopolysaccharide-stimulated peritoneal macrophages.
Journal of the Reticuloendothelial Society 1981;30(5):445-50.
1981: Grimm L J; Knapp D R; Senator D; Halushka P V
Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation.
Thrombosis research 1981;24(4):307-17.
1981: Halushka P V; Wise W C; Cook J A
Protective effects of aspirin in endotoxic shock.
The Journal of pharmacology and experimental therapeutics 1981;218(2):464-9.
1981: Halushka P V; Rogers R C; Loadholt C B; Colwell J A
Increased platelet thromboxane synthesis in diabetes mellitus.
The Journal of laboratory and clinical medicine 1981;97(1):87-96.
1981: Colwell J A; Lopes-Virella M; Halushka P V
Pathogenesis of atherosclerosis in diabetes mellitus.
Diabetes care 1981;4(1):121-33.
1981: Cook J A; Wise W C; Knapp D R; Halushka P V
Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2.
Circulatory shock 1981;8(1):69-76.
1981: Halushka P V; Rogers R C; Loadholt C B; Wohltman H; Mayfield R; McCoy S; Colwell J A
Increased platelet prostaglandin and thromboxane synthesis in diabetes mellitus.
Hormone and metabolic research. Supplement series 1981;11():7-11.
1981: Wise W C; Cook J A; Halushka P V
Implications for thromboxane A2 in the pathogenesis of endotoxic shock.
Advances in shock research 1981;6():83-91.
1981: Cook J A; Wise W C; Knapp D R; Halushka P V
Essential fatty acid deficient rats: a new model for evaluating arachidonate metabolism in shock.
Advances in shock research 1981;6():93-105.
1981: Halushka P V; Mayfield R; Wohltmann H J; Rogers R C; Goldberg A K; McCoy S A; Loadholt C B; Colwell J A
Increased platelet arachidonic acid metabolism in diabetes mellitus.
Diabetes 1981;30(Suppl 2):44-8.
1980: Burch R M; Halushka P V
Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder.
The Journal of clinical investigation 1980;66(6):1251-7.
1980: Wise W C; Cook J A; Eller T; Halushka P V
Ibuprofen improves survival from endotoxic shock in the rat.
The Journal of pharmacology and experimental therapeutics 1980;215(1):160-4.
1980: Burch R M; Knapp D R; Halushka P V
Vasopressin-stimulated water flow is decreased by thromboxane synthesis inhibition or antagonism.
The American journal of physiology 1980;239(2):F160-6.
1980: Wise W C; Cook J A; Halushka P V; Knapp D R
Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock.
Circulation research 1980;46(6):854-9.
1980: Halushka P V; Levanho A; Auber M
Arachidonic acid stimulates short-circuit current in the isolated toad urinary bladder.
The Journal of pharmacology and experimental therapeutics 1980;213(3):462-7.
1980: Colwell J A; Halushka P V
Platelet function in diabetes mellitus.
British journal of haematology 1980;44(4):521-6.
1980: Korn J H; Halushka P V; LeRoy E C
Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production.
The Journal of clinical investigation 1980;65(2):543-54.
1980: Cook J A; Wise W C; Halushka P V
Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency.
The Journal of clinical investigation 1980;65(1):227-30.
1980: Burch R M; Knapp D R; Halushka P V
Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of thromboxane synthesis inhibition.
Advances in prostaglandin and thromboxane research 1980;6():505-9.
1980: Halushka P V; Levanho A; Auber M
Prostacyclin stimulates short circuit current in the isolated toad (Bufo marinus) urinary bladder.
Advances in prostaglandin and thromboxane research 1980;8():1269-72.
1979: Halushka P V; Margolius H S; Allen H; Conradi E C
Urinary excretion of prostaglandin E like material and kallikrein: effects of furosemide.
Prostaglandins 1979;18(3):359-68.
1979: Burch R M; Knapp D R; Halushka P V
Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole.
The Journal of pharmacology and experimental therapeutics 1979;210(3):344-8.
1979: Le Breton G C; Venton D L; Enke S E; Halushka P V
13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(8):4097-101.
1979: Colwell J A; Nair R M; Halushka P V; Rogers C; Whetsell A; Sagel J
Platelet adhesion and aggregation in diabetes mellitus.
Metabolism: clinical and experimental 1979;28(4 Suppl 1):394-400.
1979: Hsu C Y; Knapp D R; Halushka P V
The effects of alpha adrenergic agents on human platelet aggregation.
The Journal of pharmacology and experimental therapeutics 1979;208(3):366-70.
1979: Colwell J A; Halushka P V; Sarji K E; Lopes-Virella M F; Sagel J
Vascular disease in diabetes: pathophysiological mechanisms and therapy.
Archives of internal medicine 1979;139(2):225-30.
1979: Halushka P V; Knapp D R; Grimm L
Prostaglandins, thromboxanes, and platelet function.
Current topics in hematology 1979;2():75-143.
1978: Colwell J A; Halushka P V; Sarji K E; Sagel J
Platelet function and diabetes mellitus.
The Medical clinics of North America 1978;62(4):753-66.
1978: Webb J G; Saelens D A; Halushka P V
Biosynthesis of prostaglandin E by rat superior cervical ganglia.
Journal of neurochemistry 1978;31(1):13-9.
1978: Maxwell W A; Halushka P V; Miller R L; Spicer S S; Westphal M C; Penny L D
Elevated prostaglandin production in cultured cells from a patient with fibrodysplasia ossificans progressiva.
Prostaglandins 1978;15(1):123-9.
1978: Colwell J A; Halushka P V; Sarji K E; Sagal J
Rationale for antiplatelet agents in diabetic vascular disease.
Advances in experimental medicine and biology 1978;102():243-54.
1977: Halushka P V; Lurie D; Colwell J A
Increased synthesis of prostaglandin-E-like material by platelets from patients with diabetes mellitus.
The New England journal of medicine 1977;297(24):1306-10.
1977: Sawyer P R; Cowart T D; Hurwitz G A; Halushka P V; Jollow D J
Acetaminophen overdosage.
Journal of the South Carolina Medical Association (1975) 1977;73(11):474-80.
1977: Halushka P V; Wohltmann H; Privitera P J; Hurwitz G; Margolius H S
Bartter's syndrome: urinary prostaglandin E-like material and kallikrein; indomethacin effects.
Annals of internal medicine 1977;87(3):281-6.
1977: Miller R L; Maxwell W A; Spicer S S; Halushka P V; Varner H H; Westphal M C
Studies on alkaline phosphatase activity cultured cells from a patient with fibrodysplasia ossificans progressiva.
Laboratory investigation; a journal of technical methods and pathology 1977;37(3):254-9.
1977: Maxwell W A; Spicer S S; Miller R L; Halushka P V; Westphal M C; Setser M E
Histochemical and ultrastructural studies in fibrodysplasia ossificans progressiva (myositis ossificans progressiva).
The American journal of pathology 1977;87(3):483-98.
1976: Colwell J A; Halushka P V; Sarji K; Levine J; Sagel J; Nair R M
Altered platelet function in diabetes mellitus.
Diabetes 1976;25(2 SUPPL):826-31.
1974: Halushka P V; Keiser H R
Acute effects of alpha-methyldopa on mean blood pressure and plasma renin activity.
Circulation research 1974;35(3):458-63.
1974: Brereton H D; Halushka P V; Alexander R W; Mason D M; Keiser H R; DeVita V T
Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma.
The New England journal of medicine 1974;291(2):83-5.
1970: Whitsett T L; Halushka P V; Goldberg L I
Attenuation of postganglionic sympathetic nerve activity by L-dopa.
Circulation research 1970;27(4):561-70.
1970: Halushka P V; Hoffmann P C
Alcohol addiction and tetrahydropapaveroline.
Science (New York, N.Y.) 1970;169(950):1104-5.
1968: Halushka P V; Hoffmann P C
Distribution and metabolism of dopamine in guinea-pigs.
The Journal of pharmacy and pharmacology 1968;20(12):943-6.
1968: Halushka P V; Hoffmann P C
Does tetrahydroparaveroline contribute to the cardiovascular actions of dopamine?
Biochemical pharmacology 1968;17(9):1873-80.

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