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Perry Halushka

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Chemicals & Drugs

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Publications

TOP 3
Pengfei Li; Richard Neubig; Basilia Zingarelli; KT Borg; James A Cook; Perry V Halushka; Hongkuan Fan
Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Gα(i2) protein.
Hongkuan Fan; Perry V Halushka; Donald Wong; Sarah H Ashton; KT Borg; James A Cook
Beneficial effect of a CXCR4 agonist in murine models of systemic inflammation.
Omar Moussa; Dennis Watson; Andrew Ciupek; Perry V Halushka
Urinary thromboxane B2 and thromboxane receptors in bladder cancer: opportunity for detection and monitoring.

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2012: Pengfei Li; Richard Neubig; Basilia Zingarelli; KT Borg; James A Cook; Perry V Halushka; Hongkuan Fan
Toll-like receptor-induced inflammatory cytokines are suppressed by gain of function or overexpression of Gα(i2) protein.
Inflammation 2012;35(5):1611-7.
2012: Hongkuan Fan; Perry V Halushka; Donald Wong; Sarah H Ashton; KT Borg; James A Cook
Beneficial effect of a CXCR4 agonist in murine models of systemic inflammation.
Inflammation 2012;35(1):130-7.
2011: Omar Moussa; Dennis Watson; Andrew Ciupek; Perry V Halushka
Urinary thromboxane B2 and thromboxane receptors in bladder cancer: opportunity for detection and monitoring.
Prostaglandins & other lipid mediators 2011;96(1-4):41-4.
2011: Pengfei Li; Louis M Luttrell; Liping Wang; KT Borg; James A Cook; Gary S Gilkeson; Perry V Halushka; Hongkuan Fan
Increased expression of beta-arrestin 1 and 2 in murine models of rheumatoid arthritis: isoform specific regulation of inflammation.
Molecular immunology 2011;49(1-2):64-74.
2011: Hongkuan Fan; Pengfei Li; Basilia Zingarelli; Keith Borg; Perry V Halushka; Lutz Birnbaumer; James A Cook
Heterotrimeric Gα(i) proteins are regulated by lipopolysaccharide and are anti-inflammatory in endotoxemia and polymicrobial sepsis.
Biochimica et biophysica acta 2011;1813(3):466-72.
2011: Jim C Oates; Perry V Halushka; Florence N Hutchison; Phillip Ruiz; Gary S Gilkeson
Selective cyclooxygenase-2 inhibitor suppresses renal thromboxane production but not proliferative lesions in the MRL/lpr murine model of lupus nephritis.
The American journal of the medical sciences 2011;341(2):101-5.
2010: Hongkuan Fan; Alessandra Bitto; Basilia Zingarelli; Louis M Luttrell; KT Borg; Perry V Halushka; James A Cook
Beta-arrestin 2 negatively regulates sepsis-induced inflammation.
Immunology 2010;130(3):344-51.
2009: Perry V Halushka; Edward L Krug
Is the training of biomedical scientists at a crossroads?
Academic medicine : journal of the Association of American Medical Colleges 2009;84(4):421-3.
2008: Hongkuan Fan; Basilia Zingarelli; Vashaunta Harris; George E Tempel; Perry V Halushka; James A Cook
Lysophosphatidic acid inhibits bacterial endotoxin-induced pro-inflammatory response: potential anti-inflammatory signaling pathways.
Molecular medicine (Cambridge, Mass.) 2008;14(7-8):422-8.
2008: Omar Moussa; Anthony W Ashton; Mostafa Fraig; Elizabeth Garrett-Mayer; Mohamed A Ghoneim; Perry V Halushka; Dennis Watson
Novel role of thromboxane receptors beta isoform in bladder cancer pathogenesis.
Cancer research 2008;68(11):4097-104.
2008: Omar Moussa; J M Riker; J Klein; Mostafa Fraig; Perry V Halushka; Dennis Watson
Inhibition of thromboxane synthase activity modulates bladder cancer cell responses to chemotherapeutic agents.
Oncogene 2008;27(1):55-62.
2008: Fahmin Basher; Hongkuan Fan; Basilia Zingarelli; KT Borg; Louis M Luttrell; George E Tempel; Perry V Halushka; James A Cook
beta-Arrestin 2: a Negative Regulator of Inflammatory Responses in Polymorphonuclear Leukocytes.
International journal of clinical and experimental medicine 2008;1(1):32-41.
2007: Hongkuan Fan; David L Williams; Basilia Zingarelli; Kevin F Breuel; Giuseppe Teti; George E Tempel; Karsten Spicher; Guylain Boulay; Lutz Birnbaumer; Perry V Halushka; James A Cook
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in macrophages by Galpha(i) proteins.
Immunology 2007;122(1):116-23.
2007: Hongkuan Fan; Louis M Luttrell; George E Tempel; Joseph J Senn; Perry V Halushka; James A Cook
Beta-arrestins 1 and 2 differentially regulate LPS-induced signaling and pro-inflammatory gene expression.
Molecular immunology 2007;44(12):3092-9.
2006: Hongkuan Fan; David L Williams; Basilia Zingarelli; Kevin F Breuel; Giuseppe Teti; George E Tempel; Karsten Spicher; Guylain Boulay; Lutz Birnbaumer; Perry V Halushka; James A Cook
Differential regulation of lipopolysaccharide and Gram-positive bacteria induced cytokine and chemokine production in splenocytes by Galphai proteins.
Biochimica et biophysica acta 2006;1763(10):1051-8.
2006: Octavia M Peck; Basilia Zingarelli; Hongkuan Fan; Giuseppe Teti; George E Tempel; Perry V Halushka; James A Cook
The phosphatidylinositol 3 kinase pathway regulates tolerance to lipopolysaccharide and priming responses to Staphylococcus aureus and lipopolysaccharide.
Shock (Augusta, Ga.) 2006;26(1):31-6.
2006: Marc K Halushka; Perry V Halushka
Toward individualized analgesic therapy: functional cyclooxygenase 1 and 2 haplotypes.
Clinical pharmacology and therapeutics 2006;79(5):404-6.
2006: Hongkuan Fan; David L Williams; Kevin F Breuel; Basilia Zingarelli; Giuseppe Teti; George E Tempel; Perry V Halushka; James A Cook
Gi proteins regulate lipopolysaccharide and Staphylococcus aureus induced cytokine production but not (1--> 3)-beta-D-glucan induced cytokine suppression.
Frontiers in bioscience : a journal and virtual library 2006;11():2264-74.
2005: Omar Moussa; John S Yordy; Hassan Abol-Enein; Debajyoti Sinha; Nabil K Bissada; Perry V Halushka; Mohamed A Ghoneim; Dennis Watson
Prognostic and functional significance of thromboxane synthase gene overexpression in invasive bladder cancer.
Cancer research 2005;65(24):11581-7.
2005: Hongkuan Fan; Basilia Zingarelli; Octavia M Peck; Giuseppe Teti; George E Tempel; Perry V Halushka; Karsten Spicher; Guylain Boulay; Lutz Birnbaumer; James A Cook
Lipopolysaccharide- and gram-positive bacteria-induced cellular inflammatory responses: role of heterotrimeric Galpha(i) proteins.
American journal of physiology. Cell physiology 2005;289(2):C293-301.
2005: Adesuyi Ajayi ; Perry V Halushka
Castration reduces platelet thromboxane A2 receptor density and aggregability.
QJM : monthly journal of the Association of Physicians 2005;98(5):349-56.
2005: Robert Malcolm; Steven D LaRowe; Kristi Cochran; Darlene Moak; Janice Herron; Kathleen T Brady; Sarra Hedden; Robert F Woolson; Perry V Halushka
A controlled trial of amlodipine for cocaine dependence: a negative report.
Journal of substance abuse treatment 2005;28(2):197-204.
2004: Hongkuan Fan; Octavia M Peck; George E Tempel; Perry V Halushka; James A Cook
Toll-like receptor 4 coupled GI protein signaling pathways regulate extracellular signal-regulated kinase phosphorylation and AP-1 activation independent of NFkappaB activation.
Shock (Augusta, Ga.) 2004;22(1):57-62.
2004: Octavia M Peck; Hongkuan Fan; George E Tempel; Giuseppe Teti; Perry V Halushka; James A Cook
Staphylococcus aureus and lipopolysaccharide induce homologous tolerance but heterologous priming: role of interferon-gamma.
Shock (Augusta, Ga.) 2004;21(3):254-60.
2003: Na Qiao; Denis Reynaud; Peter Demin; Perry V Halushka; Cecil R Pace-Asciak
The thromboxane receptor antagonist PBT-3, a hepoxilin stable analog, selectively antagonizes the TPalpha isoform in transfected COS-7 cells.
The Journal of pharmacology and experimental therapeutics 2003;307(3):1142-7.
2003: Dawne M Taylor; Perry V Halushka; G Patrick Meier
Hydrogen bond interactions of a series of N-substituted TXA2 receptor antagonists.
European journal of medicinal chemistry 2003;38(11-12):1015-24.
2003: Kelly Guyton; Basilia Zingarelli; Sarah Ashton; Giuseppe Teti; George E Tempel; Chris Reilly; Gary S Gilkeson; Perry V Halushka; James A Cook
Peroxisome proliferator-activated receptor-gamma agonists modulate macrophage activation by gram-negative and gram-positive bacterial stimuli.
Shock (Augusta, Ga.) 2003;20(1):56-62.
2003: Hongkuan Fan; Giuseppe Teti; Sarah Ashton; Kelly Guyton; George E Tempel; Perry V Halushka; James A Cook
Involvement of G(i) proteins and Src tyrosine kinase in TNFalpha production induced by lipopolysaccharide, group B Streptococci and Staphylococcus aureus.
Cytokine 2003;22(5):126-33.
2003: Donna D Gale; Peter Hofer; Domenico Spina; Esther A Seeds; Katherine H Banner; Selina Harrison; Gary Douglas; Tatsui Matsumoto; Clive P Page; Richard H Wong; Stephan Jordan; Forrest Smith; Nandini Banik; Perry V Halushka; David Cavalla; Yakov Rotshteyn; Donald J Kyle; Ronald M Burch; Mark Chasin
Pharmacology of a new cyclic nucleotide phosphodiesterase type 4 inhibitor, V11294.
Pulmonary pharmacology & therapeutics 2003;16(2):97-104.
2003: Marc K Halushka; Linda P Walker; Perry V Halushka
Genetic variation in cyclooxygenase 1: effects on response to aspirin.
Clinical pharmacology and therapeutics 2003;73(1):122-30.
2002: Robert Malcolm; Jason Liao; Melissa Michel; Kristi Cochran; Wesley Pye; Derik Yeager; Perry V Halushka
Amlodipine reduces blood pressure and headache frequency in cocaine-dependent outpatients.
Journal of psychoactive drugs 2002;34(4):415-9.
2002: Marc K Halushka; Perry V Halushka
Why are some individuals resistant to the cardioprotective effects of aspirin? Could it be thromboxane A2?
Circulation 2002;105(14):1620-2.
2002: Marcella Ferlito; Olga G Romanenko; Kelly Guyton; Sarah Ashton; Francesco Squadrito; Perry V Halushka; James A Cook
Implication of Galpha i proteins and Src tyrosine kinases in endotoxin-induced signal transduction events and mediator production.
Journal of endotoxin research 2002;8(6):427-35.
2001: George E Tempel; Alan N Brown; Thomas A Morinelli; Perry V Halushka; James A Cook
Changes in vascular responsiveness to a thromboxane mimetic in endotoxin tolerance.
Shock (Augusta, Ga.) 2001;16(5):389-92.
2001: Marcella Ferlito; O G Romanenko; Sarah Ashton; Francesco Squadrito; Perry V Halushka; James A Cook
Effect of cross-tolerance between endotoxin and TNF-alpha or IL-1beta on cellular signaling and mediator production.
Journal of leukocyte biology 2001;70(5):821-9.
2001: Thomas Walle; U Kristina Walle; Perry V Halushka
Carbon dioxide is the major metabolite of quercetin in humans.
The Journal of nutrition 2001;131(10):2648-52.
2001: Richard D Minshall; Dusan Pavcnik; Perry V Halushka; Kent Hermsmeyer
Progesterone regulation of vascular thromboxane A(2) receptors in rhesus monkeys.
American journal of physiology. Heart and circulatory physiology 2001;281(4):H1498-507.
2001: Kelly Guyton; R Bond; Chris Reilly; Gary S Gilkeson; Perry V Halushka; James A Cook
Differential effects of 15-deoxy-delta(12,14)-prostaglandin J2 and a peroxisome proliferator-activated receptor gamma agonist on macrophage activation.
Journal of leukocyte biology 2001;69(4):631-8.
2001: Marcella Ferlito; Francesco Squadrito; Perry V Halushka; James A Cook
Signal transduction events in Chinese hamster ovary cells expressing human CD14; effect of endotoxin desensitization.
Shock (Augusta, Ga.) 2001;15(4):291-6.
2001: Christopher M Reilly; Jim Oates; J Sudian; Michelle B Crosby; Perry V Halushka; Gary S Gilkeson
Prostaglandin J(2) inhibition of mesangial cell iNOS expression.
Clinical immunology (Orlando, Fla.) 2001;98(3):337-45.
2001: Thomas Walle; Y Otake; J A Brubaker; U Kristina Walle; Perry V Halushka
Disposition and metabolism of the flavonoid chrysin in normal volunteers.
British journal of clinical pharmacology 2001;51(2):143-6.
2000: Lawrence P Fernando; Anthony N Fernando; Marcella Ferlito; Perry V Halushka; James A Cook
Suppression of Cox-2 and TNF-alpha mRNA in endotoxin tolerance: effect of cycloheximide, antinomycin D, and okadaic acid.
Shock (Augusta, Ga.) 2000;14(2):128-33.
2000: Perry V Halushka
Thromboxane A(2) receptors: where have you gone?
Prostaglandins & other lipid mediators 2000;60(4-6):175-89.
2000: Christopher M Reilly; Jim Oates; James A Cook; J D Morrow; Perry V Halushka; Gary S Gilkeson
Inhibition of mesangial cell nitric oxide in MRL/lpr mice by prostaglandin J2 and proliferator activation receptor-gamma agonists.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1498-504.
1999: Kevin P Becker; Maria N Garnovskaya; Thomas W Gettys; Perry V Halushka
Coupling of thromboxane A2 receptor isoforms to Galpha13: effects on ligand binding and signalling.
Biochimica et biophysica acta 1999;1450(3):288-96.
1999: Lawrence P Fernando; MA Makhlouf; Anthony N Fernando; Sarah Ashton; Perry V Halushka; James A Cook
Tolerance to LPS decreases macrophage G protein content.
Shock (Augusta, Ga.) 1999;11(5):330-5.
1998: Siddharama Pawate; Kevin L Schey; G Patrick Meier; Michael E Ullian; D E Mais; Perry V Halushka
Expression, characterization, and purification of C-terminally hexahistidine-tagged thromboxane A2 receptors.
The Journal of biological chemistry 1998;273(35):22753-60.
1998: Kevin P Becker; Michael E Ullian; Perry V Halushka
Cloning and characterization of an endogenous COS-7 cell thromboxane A2 receptor.
Biochimica et biophysica acta 1998;1403(1):109-14.
1998: M Durando; Lawrence P Fernando; Sarah Ashton; Perry V Halushka; James A Cook
Suppressed thromboxane production in endotoxin-desensitized THP-1 cells is not a result of decreased prostaglandin H synthase activity.
Shock (Augusta, Ga.) 1998;9(5):359-63.
1998: MA Makhlouf; Lawrence P Fernando; Thomas W Gettys; Perry V Halushka; James A Cook
Increased prostacyclin and PGE2 stimulated cAMP production by macrophages from endotoxin-tolerant rats.
The American journal of physiology 1998;274(5 Pt 1):C1238-44.
1998: G R Wang; Yan Zhu; Perry V Halushka; T M Lincoln; M E Mendelsohn
Mechanism of platelet inhibition by nitric oxide: in vivo phosphorylation of thromboxane receptor by cyclic GMP-dependent protein kinase.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(9):4888-93.
1998: MA Makhlouf; B Zingarelli; Perry V Halushka; James A Cook
Endotoxin tolerance alters macrophage membrane regulatory G proteins.
Progress in clinical and biological research 1998;397():217-26.
1997: K Higashiura; Rajesh S Mathur; Perry V Halushka
Gender-related differences in androgen regulation of thromboxane A2 receptors in rat aortic smooth-muscle cells.
Journal of cardiovascular pharmacology 1997;29(3):311-5.
1997: Thomas E Brothers; Jacob G Robison; Bruce M Elliott; J M Boggs; Perry V Halushka
Thromboxane A2 receptor density increases during chronic exposure to thromboxane A2 receptor antagonists after porcine carotid bypass.
Cardiovascular surgery (London, England) 1997;5(1):92-8.
1997: K Schrör; K Davis-Bruno; Perry V Halushka
Modification on ligand binding to TXA2/PGH2 receptors by diethylpyrocarbonate.
Advances in experimental medicine and biology 1997;400A():235-40.
1996: K Higashiura; B Blaney; E Morgan; R S Mathur; Perry V Halushka
Inhibition of testosterone 5 alpha-reductase: evidence for tissue-specific regulation of thromboxane A2 receptors.
The Journal of pharmacology and experimental therapeutics 1996;279(3):1386-91.
1996: M Makhlouf; Sarah Ashton; John D Hildebrandt; N Mehta; Thomas W Gettys; Perry V Halushka; James A Cook
Alterations in macrophage G proteins are associated with endotoxin tolerance.
Biochimica et biophysica acta 1996;1312(2):163-8.
1996: C J Allan; K Higashiura; M Martin; Thomas A Morinelli; David Thomas Kurtz; O Geoffroy; G P Meier; Thomas W Gettys; Perry V Halushka
Characterization of the cloned HEL cell thromboxane A2 receptor: evidence that the affinity state can be altered by G alpha 13 and G alpha q.
The Journal of pharmacology and experimental therapeutics 1996;277(2):1132-9.
1996: R S Wagner; Perry V Halushka; James A Cook
Activation of thromboxane A2 receptors alters lipopolysaccharide-induced adherence of THP-1 cells.
Shock (Augusta, Ga.) 1996;5(1):41-6.
1996: Richard V Paul; H Saxenhofer; P S Wackym; Perry V Halushka
Stimulation of rat mesangial cell thromboxane A2 receptors inhibits particulate but not soluble guanylyl cyclase.
The American journal of physiology 1996;270(1 Pt 2):F31-8.
1996: T P Zucker; K Higashiura; R S Mathur; Perry V Halushka
Androstenedione increases thromboxane A2 receptors in human erythroleukemia cells.
Life sciences 1996;58(8):683-90.
1995: Perry V Halushka; C J Allan; K L Davis-Bruno
Thromboxane A2 receptors.
Journal of lipid mediators and cell signalling 1995;12(2-3):361-78.
1995: A A Ajayi; R Mathur; Perry V Halushka
Testosterone increases human platelet thromboxane A2 receptor density and aggregation responses.
Circulation 1995;91(11):2742-7.
1995: K Schrör; K Davis-Bruno; Perry V Halushka
Inhibition of ligand binding to thromboxane A2/prostaglandin H2 receptors by diethylpyrocarbonate. Protection by receptor ligands and reversal by hydroxylamine.
Biochemical pharmacology 1995;49(7):921-7.
1995: K Matsuda; R S Mathur; Michael E Ullian; Perry V Halushka
Sex steroid regulation of thromboxane A2 receptors in cultured rat aortic smooth muscle cells.
Prostaglandins 1995;49(3):183-96.
1995: B Zingarelli; Perry V Halushka; A P Caputi; James A Cook
Increased nitric oxide synthesis during the development of endotoxin tolerance.
Shock (Augusta, Ga.) 1995;3(2):102-8.
1995: B Zingarelli; H Chen; A P Caputi; Perry V Halushka; James A Cook
Reorientation of macrophage mediator production in endotoxin tolerance.
Progress in clinical and biological research 1995;392():529-37.
1995: A A Ajayi; K Matsuda; K Schrör; A Masuda; R Mathur; Perry V Halushka
Androgen regulation of thromboxane A2 receptors.
Advances in prostaglandin, thromboxane, and leukotriene research 1995;23():251-3.
1995: TP Zucker; Tilo Grosser; Thomas A Morinelli; Perry V Halushka; Agapios Sachinidis; H Vetter; Karsten Schrör
Potentiation of PDGF-induced growth responses in coronary artery smooth muscle cells by thromboxane.
Agents and actions. Supplements 1995;45():53-8.
1995: Perry V Halushka; K Matsuda; A Masuda; A Ruff; Thomas A Morinelli; R S Mathur
Testosterone regulation of platelet and vascular thromboxane A2 receptors.
Agents and actions. Supplements 1995;45():19-26.
1994: J Geisel; James A Cook; Sarah Ashton; W C Wise; Perry V Halushka
Endotoxin tolerance is associated with decreased prostaglandin H synthases-1 and -2.
The American journal of physiology 1994;267(4 Pt 1):C1067-72.
1994: K Matsuda; A Ruff; Thomas A Morinelli; R S Mathur; Perry V Halushka
Testosterone increases thromboxane A2 receptor density and responsiveness in rat aortas and platelets.
The American journal of physiology 1994;267(3 Pt 2):H887-93.
1994: K Yin; Perry V Halushka; Y T Yan; PY Wong
Antiaggregatory activity of 8-epi-prostaglandin F2 alpha and other F-series prostanoids and their binding to thromboxane A2/prostaglandin H2 receptors in human platelets.
The Journal of pharmacology and experimental therapeutics 1994;270(3):1192-6.
1994: C J Allan; Perry V Halushka
Characterization of human peripheral blood monocyte thromboxane A2 receptors.
The Journal of pharmacology and experimental therapeutics 1994;270(2):446-52.
1994: C J Buzzard; S L Pfister; Perry V Halushka; W B Campbell
Decrease in vascular TxA2 receptors in a subgroup of rabbits unresponsive to a TxA2 mimetic.
The American journal of physiology 1994;266(6 Pt 2):H2320-6.
1994: H Chen; Perry V Halushka; James A Cook
Endotoxin tolerance: effects on lethality and macrophage thromboxane (B2) and interleukin 6 production.
Shock (Augusta, Ga.) 1994;1(5):366-71.
1994: A K Okwu; D E Mais; Perry V Halushka
Agonist-induced phosphorylation of human platelet TXA2/PGH2 receptors.
Biochimica et biophysica acta 1994;1221(1):83-8.
1994: K Schrör; Thomas A Morinelli; A Masuda; K Matsuda; R S Mathur; Perry V Halushka
Testosterone treatment enhances thromboxane A2 mimetic induced coronary artery vasoconstriction in guinea pigs.
European journal of clinical investigation 1994;24 Suppl 1():50-2.
1994: C A Rinder; Perry V Halushka; Mary Ann Sens; David W Ploth
Thromboxane A2 receptor blockade improves renal function and histopathology in the post-obstructive kidney.
Kidney international 1994;45(1):185-92.
1994: Perry V Halushka; A Masuda; K Matsuda
The Gordon Wilson Lecture. Regulation of thromboxane A2 receptors by testosterone: implications for steroid abuse and cardiovascular disease.
Transactions of the American Clinical and Climatological Association 1994;105():95-103.
1993: K Matsuda; R S Mathur; Emir Duzic; Perry V Halushka
Androgen regulation of thromboxane A2/prostaglandin H2 receptor expression in human erythroleukemia cells.
The American journal of physiology 1993;265(6 Pt 1):E928-34.
1993: N Liel; I Nathan; T Yermiyahu; Z Zolotov; J R Lieberman; A Dvilansky; Perry V Halushka
Increased platelet thromboxane A2/prostaglandin H2 receptors in patients with pregnancy induced hypertension.
Thrombosis research 1993;70(3):205-10.
1993: Thomas A Morinelli; George E Tempel; Ayad A Jaffa; R H Silva; M Naka; W Folger; Perry V Halushka
Thromboxane A2/prostaglandin H2 receptors in streptozotocin-induced diabetes: effects of insulin therapy in the rat.
Prostaglandins 1993;45(5):427-38.
1993: Giovanni Matera; James A Cook; J Geisel; Sarah Ashton; W C Wise; A Focá; B A Berkowitz; Perry V Halushka
Effects of two magainin peptides on eicosanoid release from rat peritoneal macrophages.
Antimicrobial agents and chemotherapy 1993;37(3):393-7.
1993: T R Simmons; James A Cook; James N Moore; Perry V Halushka
Thromboxane A2 receptors in equine monocytes: identification of a new subclass of TXA2 receptors.
Journal of leukocyte biology 1993;53(2):173-8.
1993: James A Cook; J Geisel; Perry V Halushka; H D Reines
Prostaglandins, thromboxanes, leukotrienes, and cytochrome P-450 metabolites of arachidonic acid.
New horizons (Baltimore, Md.) 1993;1(1):60-9.
1992: W H Folger; Perry V Halushka; Christopher Wilcox; N J Guzman
Characterization of rat glomerular thromboxane A2 receptors: comparison to rat platelets.
European journal of pharmacology 1992;227(1):71-8.
1992: K A Coffee; Perry V Halushka; Sarah Ashton; George E Tempel; W C Wise; James A Cook
Endotoxin tolerance is associated with altered GTP-binding protein function.
Journal of applied physiology (Bethesda, Md. : 1985) 1992;73(3):1008-13.
1992: M Naka; D E Mais; Thomas A Morinelli; N Hamanaka; John E Oatis; Perry V Halushka
7-[(1R,2S,3S,5R)-6,6-dimethyl-3-(4- iodobenzenesulfonylamino)bicyclo[3.1.1]hept-2-yl]-5(Z)-heptenoic acid: a novel high-affinity radiolabeled antagonist for platelet thromboxane A2/prostaglandin H2 receptors.
The Journal of pharmacology and experimental therapeutics 1992;262(2):632-7.
1992: A K Okwu; Michael E Ullian; Perry V Halushka
Homologous desensitization of human platelet thromboxane A2/prostaglandin H2 receptors.
The Journal of pharmacology and experimental therapeutics 1992;262(1):238-45.
1991: gordon bernard; H D Reines; Perry V Halushka; S B Higgins; C A Metz; Bridget B Swindell; P E Wright; F L Watts; J J Vrbanac
Prostacyclin and thromboxane A2 formation is increased in human sepsis syndrome. Effects of cyclooxygenase inhibition.
The American review of respiratory disease 1991;144(5):1095-101.
1991: A Masuda; R Mathur; Perry V Halushka
Testosterone increases thromboxane A2 receptors in cultured rat aortic smooth muscle cells.
Circulation research 1991;69(3):638-43.
1991: J Geisel; James A Cook; K A Coffee; W C Wise; Perry V Halushka
Endotoxin-induced arachidonic acid metabolism requires de novo protein synthesis and protein kinase C activation.
Biochimica et biophysica acta 1991;1085(1):15-20.
1991: E J Li; James A Cook; W C Wise; W T Jackson; Perry V Halushka
Effect of LTB4 receptor antagonists in endotoxic shock in the rat.
Circulatory shock 1991;34(4):385-92.
1991: P R Mayeux; Thomas A Morinelli; T C Williams; E S Hazard; D E Mais; John E Oatis; D A Baron; Perry V Halushka
Differential effect of pH on thromboxane A2/prostaglandin H2 receptor agonist and antagonist binding in human platelets.
The Journal of biological chemistry 1991;266(21):13752-8.
1991: A Masuda; D E Mais; John E Oatis; Perry V Halushka
Platelet and vascular thromboxane A2/prostaglandin H2 receptors. Evidence for different subclasses in the rat.
Biochemical pharmacology 1991;42(3):537-44.
1991: E J Li; James A Cook; Sarah Ashton; W C Wise; Perry V Halushka
Effect of the LTD4 receptor antagonist LY203647 on endotoxic shock sequelae in the rat.
European journal of pharmacology 1991;199(2):221-5.
1991: Thomas A Morinelli; Perry V Halushka
Thromboxane-A(2)/prostaglandin-H(2) receptors Characterization and antagonism.
Trends in cardiovascular medicine 1991;1(4):157-61.
1991: D E Mais; Nancy L Bowling; T A True; M Naka; Thomas A Morinelli; John E Oatis; N Hamanaka; Perry V Halushka
Novel synthesis and biochemical properties of an [125I]-labeled photoaffinity probe for thromboxane A2/prostaglandin H2 receptors.
Journal of medicinal chemistry 1991;34(4):1511-4.
1991: P R Mayeux; D E Mais; Perry V Halushka
Interactions of dihydropyridine Ca2+ channel agonists with the human platelet thromboxane A2/prostaglandin H2 receptor.
European journal of pharmacology 1991;206(1):15-21.
1991: James N Moore; James A Cook; M M Henry; H T Jonsson; Kenneth M. Spicer; W C Wise; Perry V Halushka
Effects of a linseed oil enriched diet on endotoxin-induced sequelae: differential in vitro and in vivo effects.
Eicosanoids 1991;4(1):47-55.
1991: A Masuda; Perry V Halushka
Thromboxane A2 receptors are influenced by cell density in cultured rat aortic smooth muscle cells.
Life sciences 1991;48(25):2391-5.
1991: Thomas A Morinelli; M Naka; A Masuda; John E Oatis; A K Okwu; D E Mais; David Saussy; Perry V Halushka
Characterization of thromboxane A2/prostaglandin H2 receptors of various tissues using a new radioiodinated thromboxane A2/prostaglandin H2 mimetic, I-BOP.
Advances in prostaglandin, thromboxane, and leukotriene research 1991;21A():331-7.
1991: K A Coffee; Perry V Halushka; W C Wise; George E Tempel; James A Cook
Endotoxin tolerance differentially alters hemodynamic responses to a thromboxane A2 mimetic and phenylephrine.
Journal of cardiovascular pharmacology 1991;17(1):20-6.
1991: James L Zellner; James A Cook; H D Reines; E F Smith; L D Kessler; Perry V Halushka
Effect of a LTD4 receptor antagonist in porcine septic shock.
Eicosanoids 1991;4(3):169-75.
1990: William C Sessa; Perry V Halushka; A Okwu; Alberto Nasjletti
Characterization of the vascular thromboxane A2/prostaglandin endoperoxide receptor in rabbit aorta. Regulation by dexamethasone.
Circulation research 1990;67(6):1562-9.
1990: James A Cook; E J Li; Kenneth M. Spicer; W C Wise; Perry V Halushka
Effect of leukotriene receptor antagonists on vascular permeability during endotoxic shock.
Circulatory shock 1990;32(3):209-18.
1990: D E Mais; N Liel; Perry V Halushka
Photoaffinity receptor antagonist for human platelet thromboxane A2/prostaglandin H2 receptors.
Biochemical pharmacology 1990;40(7):1457-61.
1990: K A Coffee; Perry V Halushka; W C Wise; James A Cook
Altered responses to modulators of guanine nucleotide binding protein activity in endotoxin tolerance.
Biochimica et biophysica acta 1990;1035(2):201-5.
1990: James N Moore; James A Cook; D D Morris; Perry V Halushka; W C Wise
Endotoxin-induced procoagulant activity, eicosanoid synthesis, and tumor necrosis factor production by rat peritoneal macrophages: effect of endotoxin tolerance and glucan.
Circulatory shock 1990;31(3):281-95.
1990: E J Li; James A Cook; Kenneth M. Spicer; W C Wise; J Rokach; Perry V Halushka
Resistance of essential fatty acid-deficient rats to endotoxin-induced increases in vascular permeability.
Circulatory shock 1990;31(2):159-70.
1990: T Nishimiya; H B Daniell; Jerry G Webb; John E Oatis; Thomas Walle; T E Gaffney; Perry V Halushka
Chronic treatment with propranolol enhances the synthesis of prostaglandins E2 and I2 by the aorta of spontaneously hypertensive rats.
The Journal of pharmacology and experimental therapeutics 1990;253(1):207-13.
1990: Perry V Halushka; Thomas A Morinelli; D E Mais
Radioligand binding assays for thromboxane A2/prostaglandin H2 receptors.
Methods in enzymology 1990;187():397-405.
1990: Thomas A Morinelli; D E Mais; John E Oatis; P R Mayeux; A K Okwu; A Masuda; Daniel R Knapp; Perry V Halushka
I-BOP, the most potent radiolabelled agonist for the TXA2/PGH2 receptor.
Advances in prostaglandin, thromboxane, and leukotriene research 1990;20():102-9.
1990: Thomas A Morinelli; D E Mais; John E Oatis; Arthur J Crumbley; Perry V Halushka
Characterization of thromboxane A2/prostaglandin H2 receptors in human vascular smooth muscle cells.
Life sciences 1990;46(24):1765-72.
1990: G W Dorn; N Liel; J L Trask; D E Mais; M E Assey; Perry V Halushka
Increased platelet thromboxane A2/prostaglandin H2 receptors in patients with acute myocardial infarction.
Circulation 1990;81(1):212-8.
1990: James L Zellner; James A Cook; D H Reines; W C Wise; E F Smith; L D Kessler; Perry V Halushka
Hemodynamic effects of leukotriene (LT) D4 and a LTD4 receptor antagonist in the pig.
Eicosanoids 1990;3(4):219-24.
1989: Thomas A Morinelli; John E Oatis; A K Okwu; D E Mais; P R Mayeux; A Masuda; Daniel R Knapp; Perry V Halushka
Characterization of an 125I-labeled thromboxane A2/prostaglandin H2 receptor agonist.
The Journal of pharmacology and experimental therapeutics 1989;251(2):557-62.
1989: P R Mayeux; D E Mais; C Carr; Perry V Halushka
Human erythroleukemia cells express functional thromboxane A2/prostaglandin H2 receptors.
The Journal of pharmacology and experimental therapeutics 1989;250(3):923-7.
1989: John Heffner; James A Cook; Perry V Halushka
Human platelets modulate edema formation in isolated rabbit lungs.
The Journal of clinical investigation 1989;84(3):757-64.
1989: H A Ball; James A Cook; Kenneth M. Spicer; W C Wise; Perry V Halushka
Essential fatty acid-deficient rats are resistant to oleic acid-induced pulmonary injury.
Journal of applied physiology (Bethesda, Md. : 1985) 1989;67(2):811-6.
1989: D E Mais; C Yoakim; Y Guindon; J W Gillard; J Rokach; Perry V Halushka
Photoaffinity labelling of the human platelet thromboxane A2/prostaglandin H2 receptor.
Biochimica et biophysica acta 1989;1012(2):184-90.
1989: G H Watt; Sarah Ashton; James A Cook; W C Wise; Perry V Halushka; R M Galbraith
Alterations in plasma levels and complexing of Gc (vitamin D-binding protein) in rats with endotoxic shock.
Circulatory shock 1989;28(3):279-91.
1989: William M Lee; D Reines; G H Watt; James A Cook; W C Wise; Perry V Halushka; R M Galbraith
Alterations in Gc levels and complexing in septic shock.
Circulatory shock 1989;28(3):249-55.
1989: Thomas A Morinelli; A K Okwu; D E Mais; Perry V Halushka; V John; C K Chen; J Fried
Difluorothromboxane A2 and stereoisomers: stable derivatives of thromboxane A2 with differential effects on platelets and blood vessels.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(14):5600-4.
1989: K Powers; Derek A Fyfe; A B Taylor; Perry V Halushka; Fred A Crawford
Treatment of pulmonary vasospasm with prazosin after atrial septal defect closure in a child.
The Journal of thoracic and cardiovascular surgery 1989;97(5):802-4.
1989: T S Rogers; Perry V Halushka; W C Wise; James A Cook
Arachidonic acid turnover in peritoneal macrophages is altered in endotoxin-tolerant rats.
Biochimica et biophysica acta 1989;1001(2):169-75.
1989: W C Wise; James A Cook; George E Tempel; H D Reines; Perry V Halushka
The rat in sepsis and endotoxic shock.
Progress in clinical and biological research 1989;299():243-52.
1989: Perry V Halushka; D E Mais; P R Mayeux; Thomas A Morinelli
Thromboxane, prostaglandin and leukotriene receptors.
Annual review of pharmacology and toxicology 1989;29():213-39.
1989: Perry V Halushka
Pharmacology of thromboxane A2 receptor antagonists.
Zeitschrift für Kardiologie 1989;78 Suppl 3():42-7.
1989: D E Mais; Perry V Halushka
Photoaffinity labelling of the human platelet thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor.
Progress in clinical and biological research 1989;301():303-7.
1989: Perry V Halushka; D E Mais; Thomas A Morinelli
Thromboxane and prostacyclin receptors.
Progress in clinical and biological research 1989;301():21-8.
1989: D E Mais; Perry V Halushka
Photoaffinity labelling and isoelectric focusing of the human platelet thromboxane A2/prostaglandin H2 (TXA2/PGH2) receptor.
Advances in prostaglandin, thromboxane, and leukotriene research 1989;19():168-71.
1989: George E Tempel; J W Strong; W C Wise; James A Cook; E F Smith; Perry V Halushka
The role of eicosanoids in mediating blood flow alterations in endotoxin shock.
Progress in clinical and biological research 1989;299():33-42.
1988: P R Mayeux; H E Morton; J Gillard; A Lord; Thomas A Morinelli; A Boehm; D E Mais; Perry V Halushka
The affinities of prostaglandin H2 and thromboxane A2 for their receptor are similar in washed human platelets.
Biochemical and biophysical research communications 1988;157(2):733-9.
1988: N Liel; D E Mais; Perry V Halushka
Desensitization of platelet thromboxane A2/prostaglandin H2 receptors by the mimetic U46619.
The Journal of pharmacology and experimental therapeutics 1988;247(3):1133-8.
1988: Giovanni Matera; James A Cook; Randolph A Hennigar; George E Tempel; W C Wise; T D Oglesby; Perry V Halushka
Beneficial effects of a 5-lipoxygenase inhibitor in endotoxic shock in the rat.
The Journal of pharmacology and experimental therapeutics 1988;247(1):363-71.
1988: S A Katz; M Venkatachalam; R K Crouch; John Heffner; Perry V Halushka; W C Wise; James A Cook
Catalase pretreatment attenuates oleic acid-induced edema in isolated rabbit lung.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1301-6.
1988: John Heffner; S A Katz; Perry V Halushka; James A Cook
Human platelets attenuate oxidant injury in isolated rabbit lungs.
Journal of applied physiology (Bethesda, Md. : 1985) 1988;65(3):1258-66.
1988: H A Ball; James A Cook; Kenneth M. Spicer; C Y Hsu; Perry V Halushka
Oleic acid-induced pulmonary injury in rats: potential role of sulfidopeptide leukotrienes.
Circulatory shock 1988;26(1):59-70.
1988: D E Mais; D DeHoll; H Sightler; Perry V Halushka
Different pharmacologic activities for 13-azapinane thromboxane A2 analogs in platelets and blood vessels.
European journal of pharmacology 1988;148(3):309-15.
1988: David Saussy; D E Mais; D A Baron; Samuel H Pepkowitz; Perry V Halushka
Subcellular localization of a thromboxane A2/prostaglandin H2 receptor antagonist binding site in human platelets.
Biochemical pharmacology 1988;37(4):647-54.
1988: C Y Hsu; Perry V Halushka; Kenneth M. Spicer; Edward Leo Hogan; Henry F. Martin
Temporal profile of thromboxane-prostacyclin imbalance in experimental spinal cord injury.
Journal of the neurological sciences 1988;83(1):55-62.
1988: Perry V Halushka; A Boehm; D E Mais
Polymyxin B increases TXA2/PGH2 agonist and antagonist affinities in human platelet membranes.
Eicosanoids 1988;1(1):41-4.
1987: G W Dorn; R M Burch; P J Kochel; D E Mais; Perry V Halushka
Decrease in agonist affinity for human platelet thromboxane A2/prostaglandin H2 receptors induced by a platelet-derived supernatant.
Biochemical pharmacology 1987;36(12):1913-7.
1987: N Liel; D E Mais; Perry V Halushka
Binding of a thromboxane A2/prostaglandin H2 agonist [3H]U46619 to washed human platelets.
Prostaglandins 1987;33(6):789-97.
1987: G W Dorn; D Sens; A Chaikhouni; D Mais; Perry V Halushka
Cultured human vascular smooth muscle cells with functional thromboxane A2 receptors: measurement of U46619-induced 45calcium efflux.
Circulation research 1987;60(6):952-6.
1987: Perry V Halushka; P J Kochel; D E Mais
Binding of thromboxane A2/prostaglandin H2 agonists to human platelets.
British journal of pharmacology 1987;91(1):223-7.
1987: E F Smith; W C Wise; Perry V Halushka; James A Cook
Macrophage eicosanoid formation is stimulated by platelet arachidonic acid and prostaglandin endoperoxide transfer.
Biochimica et biophysica acta 1987;923(3):355-61.
1987: Thomas Fuhrman; M F Hollon; H D Reines; L S Olanoff; Perry V Halushka
Beneficial effects of ibuprofen in oleic acid induced lung injury.
The Journal of surgical research 1987;42(3):284-9.
1987: H L Hubbard; T D Eller; D E Mais; Perry V Halushka; R H Baker; Ian Blair; J J Vrbanac; Daniel R Knapp
Extraction of thromboxane B2 from urine using an immobilized antibody column for subsequent analysis by gas chromatography-mass spectrometry.
Prostaglandins 1987;33(2):149-60.
1987: Perry V Halushka; A M Lefer
Thromboxane A2 in health and disease.
Federation proceedings 1987;46(1):131-2.
1987: S A Katz; Perry V Halushka; W C Wise; James A Cook
Oleic acid induces pulmonary injury independent of eicosanoids in the isolated, perfused rabbit lung.
Circulatory shock 1987;22(3):221-30.
1987: A R Etemadi; George E Tempel; B A Farah; W C Wise; Perry V Halushka; James A Cook
Beneficial effects of a leukotriene antagonist on endotoxin-induced acute hemodynamic alterations.
Circulatory shock 1987;22(1):55-63.
1987: Perry V Halushka; D E Mais; David Saussy
Platelet and vascular smooth muscle thromboxane A2/prostaglandin H2 receptors.
Federation proceedings 1987;46(1):149-53.
1986: Perry V Halushka; D E Mais; M Garvin
Binding of a thromboxane A2/prostaglandin H2 receptor antagonist to guinea-pig platelets.
European journal of pharmacology 1986;131(1):49-54.
1986: D E Mais; R M Burch; John E Oatis; Daniel R Knapp; Perry V Halushka
Photoaffinity labelling of a thromboxane A2/prostaglandin H2 antagonist binding site in human platelets.
Biochemical and biophysical research communications 1986;140(1):128-33.
1986: A Chaikhouni; Fred A Crawford; P J Kochel; L S Olanoff; Perry V Halushka
Human internal mammary artery produces more prostacyclin than saphenous vein.
The Journal of thoracic and cardiovascular surgery 1986;92(1):88-91.
1986: C Y Hsu; Perry V Halushka; Edward Leo Hogan; R D Cox
Increased thromboxane level in experimental spinal cord injury.
Journal of the neurological sciences 1986;74(2-3):289-96.
1986: George E Tempel; James A Cook; W C Wise; Perry V Halushka; D Corral
Improvement in organ blood flow by inhibition of thromboxane synthetase during experimental endotoxic shock in the rat.
Journal of cardiovascular pharmacology 1986;8(3):514-9.
1986: T S Rogers; Perry V Halushka; W C Wise; James A Cook
Differential alteration of lipoxygenase and cyclooxygenase metabolism by rat peritoneal macrophages induced by endotoxin tolerance.
Prostaglandins 1986;31(4):639-50.
1986: S T Chen; C Y Hsu; Edward Leo Hogan; Perry V Halushka; O I Linet; F M Yatsu
Thromboxane, prostacyclin, and leukotrienes in cerebral ischemia.
Neurology 1986;36(4):466-70.
1986: David Saussy; D E Mais; R M Burch; Perry V Halushka
Identification of a putative thromboxane A2/prostaglandin H2 receptor in human platelet membranes.
The Journal of biological chemistry 1986;261(7):3025-9.
1986: J Armstrong; George E Tempel; James A Cook; W C Wise; Perry V Halushka
The effects of alpha adrenergic blockade on arachidonic acid metabolism and shock sequelae in endotoxemia.
Circulatory shock 1986;20(2):151-9.
1986: H A Ball; James A Cook; W C Wise; Perry V Halushka
Role of thromboxane, prostaglandins and leukotrienes in endotoxic and septic shock.
Intensive care medicine 1986;12(3):116-26.
1985: Perry V Halushka; Ronald Mayfield; John A Colwell
Insulin and arachidonic acid metabolism in diabetes mellitus.
Metabolism: clinical and experimental 1985;34(12 Suppl 1):32-6.
1985: D E Mais; R M Burch; David Saussy; P J Kochel; Perry V Halushka
Binding of a thromboxane A2/prostaglandin H2 receptor antagonist to washed human platelets.
The Journal of pharmacology and experimental therapeutics 1985;235(3):729-34.
1985: David Saussy; D E Mais; Daniel R Knapp; Perry V Halushka
Thromboxane A2 and prostaglandin endoperoxide receptors in platelets and vascular smooth muscle.
Circulation 1985;72(6):1202-7.
1985: R M Burch; D E Mais; Samuel H Pepkowitz; Perry V Halushka
Hydrodynamic properties of a thromboxane A2/prostaglandin H2 antagonist binding site solubilized from human platelets.
Biochemical and biophysical research communications 1985;132(3):961-8.
1985: Ronald Mayfield; Perry V Halushka; H J Wohltmann; Maria F Lopes-Virella; J K Chambers; C B Loadholt; John A Colwell
Platelet function during continuous insulin infusion treatment in insulin-dependent diabetic patients.
Diabetes 1985;34(11):1127-33.
1985: R M Burch; D E Mais; David Saussy; Perry V Halushka
Solubilization of a thromboxane A2/prostaglandin H2 antagonist binding site from human platelets.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(21):7434-8.
1985: James A Cook; W C Wise; Perry V Halushka
Protective effect of a selective leukotriene antagonist in endotoxemia in the rat.
The Journal of pharmacology and experimental therapeutics 1985;235(2):470-4.
1985: D A Baron; R M Burch; Perry V Halushka; S S Spicer
Blockade of colchicine-induced inhibition of vasopressin-stimulated osmotic water flow: failure to influence microtubule formation.
The American journal of physiology 1985;249(4 Pt 2):F464-9.
1985: D E Mais; P J Kochel; David Saussy; Perry V Halushka
Binding of an 125I-labeled thromboxane A2/prostaglandin H2 receptor antagonist to washed canine platelets.
Molecular pharmacology 1985;28(2):163-9.
1985: C Y Hsu; Perry V Halushka; Edward Leo Hogan; Narendra L. Banik; W A Lee; Phanor L. Perot
Alteration of thromboxane and prostacyclin levels in experimental spinal cord injury.
Neurology 1985;35(7):1003-9.
1985: G W Dorn; Perry V Halushka
Thromboxane synthetase inhibitors, thromboxane receptor antagonists, and aspirin in cardiovascular disease.
Rational drug therapy 1985;19(7):1-7.
1985: L S Olanoff; James A Cook; Perry V Halushka
Sulindac does not preserve renal prostacyclin synthesis during endotoxemia.
Prostaglandins 1985;29(6):1031-7.
1985: Perry V Halushka; H D Reines; S E Barrow; Ian Blair; C T Dollery; W Rambo; James A Cook; W C Wise
Elevated plasma 6-keto-prostaglandin F1 alpha in patients in septic shock.
Critical care medicine 1985;13(6):451-3.
1985: D E Mais; David Saussy; A Chaikhouni; P J Kochel; Daniel R Knapp; N Hamanaka; Perry V Halushka
Pharmacologic characterization of human and canine thromboxane A2/prostaglandin H2 receptors in platelets and blood vessels: evidence for different receptors.
The Journal of pharmacology and experimental therapeutics 1985;233(2):418-24.
1985: D E Mais; C Dunlap; N Hamanaka; Perry V Halushka
Further studies on the effects of epimers of thromboxane A2 antagonists on platelets and veins.
European journal of pharmacology 1985;111(1):125-8.
1985: Perry V Halushka; J MacDermot; Daniel R Knapp; T Eller; David Saussy; D Mais; Ian Blair; C T Dollery
A novel approach for the study of thromboxane A2 and prostaglandin H2 receptors using an 125I-labeled ligand.
Biochemical pharmacology 1985;34(8):1165-70.
1985: H D Reines; Perry V Halushka; James A Cook; C B Loadholt
Lack of effect of glucocorticoids upon plasma thromboxane in patients in a state of shock.
Surgery, gynecology & obstetrics 1985;160(4):320-2.
1985: H D Reines; Perry V Halushka; L S Olanoff; P S Hunt
Dazoxiben in human sepsis and adult respiratory distress syndrome.
Clinical pharmacology and therapeutics 1985;37(4):391-5.
1985: James A Cook; W C Wise; George E Tempel; Perry V Halushka
Exchange transfusions in rats with a perfluorated blood substitute: effect on thromboxane B2 levels during endotoxemia.
Circulatory shock 1985;15(3):193-204.
1985: H S Margolius; Perry V Halushka; Julie Chao; D H Miller; alan cuthbert; J A Spayne
Studies of the kallikrein-kinin system and prostaglandins in epithelial ion transport.
Society of General Physiologists series 1985;39():121-33.
1985: W C Wise; Perry V Halushka; Rebecca G Knapp; James A Cook
Ibuprofen, methylprednisolone, and gentamicin as conjoint therapy in septic shock.
Circulatory shock 1985;17(1):59-71.
1985: L S Olanoff; James A Cook; T Eller; Daniel R Knapp; Perry V Halushka
Protective effects of trans-13-APT, a thromboxane receptor antagonist, in endotoxemia.
Journal of cardiovascular pharmacology 1985;7(1):114-20.
1985: E F Smith; George E Tempel; W C Wise; Perry V Halushka; James A Cook
Experimental endotoxemia in the rat: efficacy of prostacyclin or the prostacyclin analog iloprost.
Circulatory shock 1985;16(1):1-7.
1984: R M Burch; Perry V Halushka
ADH or theophylline-induced changes in intracellular free and membrane-bound calcium.
The American journal of physiology 1984;247(6 Pt 2):F939-45.
1984: alan cuthbert; Perry V Halushka; David Kessel; H S Margolius; W C Wise
Kinin effects on chloride secretion do not require eicosanoid synthesis.
British journal of pharmacology 1984;83(2):549-54.
1984: alan cuthbert; Perry V Halushka; H S Margolius; J A Spayne
Mediators of the secretory response to kinins.
British journal of pharmacology 1984;82(3):597-607.
1984: alan cuthbert; Perry V Halushka; H S Margolius; J A Spayne
Role of calcium ions in kinin-induced chloride secretion.
British journal of pharmacology 1984;82(3):587-95.
1984: L S Olanoff; H D Reines; Kenneth M. Spicer; Perry V Halushka
Effects of oleic acid on pulmonary capillary leak and thromboxanes.
The Journal of surgical research 1984;36(6):597-605.
1984: R M Burch; Perry V Halushka
Alterations in extracellular calcium concentration differentially influence prostaglandin and thromboxane synthesis in epithelial cells from the toad urinary bladder.
Archives of biochemistry and biophysics 1984;229(1):90-7.
1984: T S Rogers; E F Smith; W C Wise; Perry V Halushka; James A Cook
Interaction of eicosanoids and macrophages during inflammatory responses.
Survey of immunologic research 1984;3(2-3):161-4.
1984: James A Cook; W C Wise; R R Butler; H D Reines; W Rambo; Perry V Halushka
The potential role of thromboxane and prostacyclin in endotoxic and septic shock.
The American journal of emergency medicine 1984;2(1):28-37.
1983: John A Colwell; P D Winocour; Maria F Lopes-Virella; Perry V Halushka
New concepts about the pathogenesis of atherosclerosis in diabetes mellitus.
The American journal of medicine 1983;75(5B):67-80.
1983: R M Burch; W C Wise; Perry V Halushka
Prostaglandin-independent inhibition of calcium transport by nonsteroidal anti-inflammatory drugs: differential effects of carboxylic acids and piroxicam.
The Journal of pharmacology and experimental therapeutics 1983;227(1):84-91.
1983: K P Chong; R M Burch; M Black; E Maloney; D J Jollow; Perry V Halushka
Vasopressin stimulates thromboxane synthesis in isolated hamster hepatocytes: relation to hepatocyte calcium content.
Prostaglandins 1983;26(3):397-408.
1983: R M Burch; Perry V Halushka
Verapamil inhibition of vasopressin-stimulated water flow: possible role of intracellular calcium.
The Journal of pharmacology and experimental therapeutics 1983;226(3):701-5.
1983: Perry V Halushka; W C Wise; James A Cook
Studies on the beneficial effects of aspirin in endotoxic shock. Relationship to inhibition of arachidonic acid metabolism.
The American journal of medicine 1983;74(6A):91-6.
1983: John A Colwell; P D Winocour; Perry V Halushka
Do platelets have anything to do with diabetic microvascular disease?
Diabetes 1983;32 Suppl 2():14-9.
1983: K Anderegg; P Anzeveno; James A Cook; Perry V Halushka; J McCarthy; E Wagner; W C Wise
Effects of a pyridine derivative thromboxane synthetase inhibitor and its inactive isomer in endotoxic shock in the rat.
British journal of pharmacology 1983;78(4):725-32.
1983: R R Butler; W C Wise; Perry V Halushka; James A Cook
Gentamicin and indomethacin in the treatment of septic shock: effects on prostacyclin and thromboxane A2 production.
The Journal of pharmacology and experimental therapeutics 1983;225(1):94-101.
1983: Walter H Newman; M B Frankis; Perry V Halushka
Increased myocardial release of prostacyclin in dogs with heart failure.
Journal of cardiovascular pharmacology 1983;5(2):194-201.
1983: W C Wise; James A Cook; Perry V Halushka
Arachidonic acid metabolism in endotoxin tolerance.
Advances in shock research 1983;10():131-42.
1983: Perry V Halushka; C T Dollery; J MacDermot
Thromboxane and prostacyclin in disease: a review.
The Quarterly journal of medicine 1983;52(208):461-70.
1983: Perry V Halushka; James A Cook; W C Wise
Beneficial effects of UK 37248, a thromboxane synthetase inhibitor, in experimental endotoxic shock in the rat.
British journal of clinical pharmacology 1983;15 Suppl 1():133S-139S.
1983: A R Hohn; D A Riopel; J E Keil; C B Loadholt; Harry S Margolius; Perry V Halushka; P J Privitera; Jerry G Webb; E S Medley; S H Schuman; M I Rubin; R H Pantell; M L Braunstein
Childhood familial and racial differences in physiologic and biochemical factors related to hypertension.
Hypertension 1983;5(1):56-70.
1983: R M Burch; Perry V Halushka
45Ca fluxes in isolated toad bladder epithelial cells: effects of agents which alter water or sodium transport.
The Journal of pharmacology and experimental therapeutics 1983;224(1):108-17.
1982: R M Burch; Perry V Halushka
Vasopressin stimulates prostaglandin and thromboxane synthesis in toad bladder epithelial cells.
The American journal of physiology 1982;243(6):F593-7.
1982: V E Kelley; S Izui; Perry V Halushka
Effect of ibuprofen, a fatty acid cyclooxygenase inhibitor, on murine lupus.
Clinical immunology and immunopathology 1982;25(2):223-31.
1982: T W Wilson; C B Loadholt; P J Privitera; Perry V Halushka
Furosemide increases urine 6-keto-prostaglandin F1 alpha. Relation to natriuresis, vasodilation, and renin release.
Hypertension 1982;4(5):634-41.
1982: H D Reines; Perry V Halushka; James A Cook; W C Wise; W Rambo
Plasma thromboxane concentrations are raised in patients dying with septic shock.
Lancet 1982;2(8291):174-5.
1982: John A Colwell; Perry V Halushka
Platelets, prostaglandins, and coagulation in diabetes mellitus.
The Mount Sinai journal of medicine, New York 1982;49(3):215-22.
1982: James A Cook; Perry V Halushka; W C Wise
Modulation of macrophage arachidonic acid metabolism: potential role in the susceptibility of rats to endotoxic shock.
Circulatory shock 1982;9(6):605-17.
1982: George E Tempel; James A Cook; W C Wise; Perry V Halushka
The improvement in endotoxin-induced redistribution of organ blood flow by inhibition of thromboxane and prostaglandin synthesis.
Advances in shock research 1982;7():209-18.
1982: R R Butler; W C Wise; Perry V Halushka; James A Cook
Thromboxane and prostacyclin production during septic shock.
Advances in shock research 1982;7():133-45.
1982: R M Burch; Perry V Halushka
Inhibition of prostaglandin synthesis antagonizes the colchicine-induced reduction of vasopressin-stimulated water flow in the toad urinary bladder.
Molecular pharmacology 1982;21(1):142-9.
1981: M P Russel; P J Privitera; Thomas Walle; N P Peet; Perry V Halushka; T E Gaffney
Cardiovascular effects of a 4'-methylthio analog of propranolol.
The Journal of pharmacology and experimental therapeutics 1981;219(3):685-90.
1981: L J Grimm; Daniel R Knapp; David Senator; Perry V Halushka
Inhibition of platelet thromboxane synthesis by 7-(1-imidazolyl) heptanoic acid: dissociation from inhibition of aggregation.
Thrombosis research 1981;24(4):307-17.
1981: James A Cook; W C Wise; Perry V Halushka
Thromboxane A2 and prostacyclin production by lipopolysaccharide-stimulated peritoneal macrophages.
Journal of the Reticuloendothelial Society 1981;30(5):445-50.
1981: Perry V Halushka; W C Wise; James A Cook
Protective effects of aspirin in endotoxic shock.
The Journal of pharmacology and experimental therapeutics 1981;218(2):464-9.
1981: Perry V Halushka; R C Rogers; C B Loadholt; John A Colwell
Increased platelet thromboxane synthesis in diabetes mellitus.
The Journal of laboratory and clinical medicine 1981;97(1):87-96.
1981: James A Cook; W C Wise; Daniel R Knapp; Perry V Halushka
Sensitization of essential fatty acid-deficient rats to endotoxin by arachidonate pretreatment: role of thromboxane A2.
Circulatory shock 1981;8(1):69-76.
1981: Perry V Halushka; R C Rogers; C B Loadholt; H Wohltman; Ronald Mayfield; S McCoy; John A Colwell
Increased platelet prostaglandin and thromboxane synthesis in diabetes mellitus.
Hormone and metabolic research. Supplement series 1981;11():7-11.
1981: John A Colwell; Maria F Lopes-Virella; Perry V Halushka
Pathogenesis of atherosclerosis in diabetes mellitus.
Diabetes care 1981;4(1):121-33.
1981: W C Wise; James A Cook; Perry V Halushka
Implications for thromboxane A2 in the pathogenesis of endotoxic shock.
Advances in shock research 1981;6():83-91.
1981: James A Cook; W C Wise; Daniel R Knapp; Perry V Halushka
Essential fatty acid deficient rats: a new model for evaluating arachidonate metabolism in shock.
Advances in shock research 1981;6():93-105.
1981: Perry V Halushka; Ronald Mayfield; H J Wohltmann; R C Rogers; A K Goldberg; S A McCoy; C B Loadholt; John A Colwell
Increased platelet arachidonic acid metabolism in diabetes mellitus.
Diabetes 1981;30(Suppl 2):44-8.
1980: R M Burch; Perry V Halushka
Thromboxane and stable prostaglandin endoperoxide analogs stimulate water permeability in the toad urinary bladder.
The Journal of clinical investigation 1980;66(6):1251-7.
1980: W C Wise; James A Cook; T Eller; Perry V Halushka
Ibuprofen improves survival from endotoxic shock in the rat.
The Journal of pharmacology and experimental therapeutics 1980;215(1):160-4.
1980: R M Burch; Daniel R Knapp; Perry V Halushka
Vasopressin-stimulated water flow is decreased by thromboxane synthesis inhibition or antagonism.
The American journal of physiology 1980;239(2):F160-6.
1980: W C Wise; James A Cook; Perry V Halushka; Daniel R Knapp
Protective effects of thromboxane synthetase inhibitors in rats in endotoxic shock.
Circulation research 1980;46(6):854-9.
1980: Perry V Halushka; A Levanho; M Auber
Arachidonic acid stimulates short-circuit current in the isolated toad urinary bladder.
The Journal of pharmacology and experimental therapeutics 1980;213(3):462-7.
1980: John A Colwell; Perry V Halushka
Platelet function in diabetes mellitus.
British journal of haematology 1980;44(4):521-6.
1980: J H Korn; Perry V Halushka; E C LeRoy
Mononuclear cell modulation of connective tissue function: suppression of fibroblast growth by stimulation of endogenous prostaglandin production.
The Journal of clinical investigation 1980;65(2):543-54.
1980: James A Cook; W C Wise; Perry V Halushka
Elevated thromboxane levels in the rat during endotoxic shock: protective effects of imidazole, 13-azaprostanoic acid, or essential fatty acid deficiency.
The Journal of clinical investigation 1980;65(1):227-30.
1980: R M Burch; Daniel R Knapp; Perry V Halushka
Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of thromboxane synthesis inhibition.
Advances in prostaglandin and thromboxane research 1980;6():505-9.
1980: Perry V Halushka; A Levanho; M Auber
Prostacyclin stimulates short circuit current in the isolated toad (Bufo marinus) urinary bladder.
Advances in prostaglandin and thromboxane research 1980;8():1269-72.
1979: Perry V Halushka; H S Margolius; H Allen; E C Conradi
Urinary excretion of prostaglandin E like material and kallikrein: effects of furosemide.
Prostaglandins 1979;18(3):359-68.
1979: R M Burch; Daniel R Knapp; Perry V Halushka
Vasopressin stimulates thromboxane synthesis in the toad urinary bladder: effects of imidazole.
The Journal of pharmacology and experimental therapeutics 1979;210(3):344-8.
1979: Guy C Le Breton; D L Venton; S E Enke; Perry V Halushka
13-Azaprostanoic acid: a specific antagonist of the human blood platelet thromboxane/endoperoxide receptor.
Proceedings of the National Academy of Sciences of the United States of America 1979;76(8):4097-101.
1979: John A Colwell; R M Nair; Perry V Halushka; C Rogers; A Whetsell; Julius Sagel
Platelet adhesion and aggregation in diabetes mellitus.
Metabolism: clinical and experimental 1979;28(4 Suppl 1):394-400.
1979: C Y Hsu; Daniel R Knapp; Perry V Halushka
The effects of alpha adrenergic agents on human platelet aggregation.
The Journal of pharmacology and experimental therapeutics 1979;208(3):366-70.
1979: John A Colwell; Perry V Halushka; K E Sarji; Maria F Lopes-Virella; Julius Sagel
Vascular disease in diabetes: pathophysiological mechanisms and therapy.
Archives of internal medicine 1979;139(2):225-30.
1979: Perry V Halushka; Daniel R Knapp; L Grimm
Prostaglandins, thromboxanes, and platelet function.
Current topics in hematology 1979;2():75-143.
1978: John A Colwell; Perry V Halushka; K E Sarji; Julius Sagel
Platelet function and diabetes mellitus.
The Medical clinics of North America 1978;62(4):753-66.
1978: Jerry G Webb; D A Saelens; Perry V Halushka
Biosynthesis of prostaglandin E by rat superior cervical ganglia.
Journal of neurochemistry 1978;31(1):13-9.
1978: W A Maxwell; Perry V Halushka; R L Miller; S S Spicer; M C Westphal; L D Penny
Elevated prostaglandin production in cultured cells from a patient with fibrodysplasia ossificans progressiva.
Prostaglandins 1978;15(1):123-9.
1978: John A Colwell; Perry V Halushka; K E Sarji; J Sagal
Rationale for antiplatelet agents in diabetic vascular disease.
Advances in experimental medicine and biology 1978;102():243-54.
1977: Perry V Halushka; D Lurie; John A Colwell
Increased synthesis of prostaglandin-E-like material by platelets from patients with diabetes mellitus.
The New England journal of medicine 1977;297(24):1306-10.
1977: P R Sawyer; T D Cowart; G A Hurwitz; Perry V Halushka; D J Jollow
Acetaminophen overdosage.
Journal of the South Carolina Medical Association (1975) 1977;73(11):474-80.
1977: Perry V Halushka; H Wohltmann; P J Privitera; G Hurwitz; H S Margolius
Bartter's syndrome: urinary prostaglandin E-like material and kallikrein; indomethacin effects.
Annals of internal medicine 1977;87(3):281-6.
1977: R L Miller; W A Maxwell; S S Spicer; Perry V Halushka; H H Varner; M C Westphal
Studies on alkaline phosphatase activity cultured cells from a patient with fibrodysplasia ossificans progressiva.
Laboratory investigation; a journal of technical methods and pathology 1977;37(3):254-9.
1977: W A Maxwell; S S Spicer; R L Miller; Perry V Halushka; M C Westphal; M E Setser
Histochemical and ultrastructural studies in fibrodysplasia ossificans progressiva (myositis ossificans progressiva).
The American journal of pathology 1977;87(3):483-98.
1976: John A Colwell; Perry V Halushka; K Sarji; J Levine; Julius Sagel; R M Nair
Altered platelet function in diabetes mellitus.
Diabetes 1976;25(2 SUPPL):826-31.
1974: Perry V Halushka; H R Keiser
Acute effects of alpha-methyldopa on mean blood pressure and plasma renin activity.
Circulation research 1974;35(3):458-63.
1974: H D Brereton; Perry V Halushka; R W Alexander; D M Mason; H R Keiser; V T DeVita
Indomethacin-responsive hypercalcemia in a patient with renal-cell adenocarcinoma.
The New England journal of medicine 1974;291(2):83-5.
1970: T L Whitsett; Perry V Halushka; L I Goldberg
Attenuation of postganglionic sympathetic nerve activity by L-dopa.
Circulation research 1970;27(4):561-70.
1970: Perry V Halushka; P C Hoffmann
Alcohol addiction and tetrahydropapaveroline.
Science (New York, N.Y.) 1970;169(3950):1104-5.
1968: Perry V Halushka; P C Hoffmann
Distribution and metabolism of dopamine in guinea-pigs.
The Journal of pharmacy and pharmacology 1968;20(12):943-6.
1968: Perry V Halushka; P C Hoffmann
Does tetrahydroparaveroline contribute to the cardiovascular actions of dopamine?
Biochemical pharmacology 1968;17(9):1873-80.