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Abdel Rahim Hamad

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Hanjuan Shao; Abdel Rahim A Hamad; Chiaki Nakata; Sherri-Gae Scott; Shukti Chakravarti
Extracellular matrix protein lumican promotes clearance and resolution of Pseudomonas aeruginosa keratitis in a mouse model.
Hanjuan Shao; Shoujun Chen; Sherri Gae-Scott; Abdel Rahim A Hamad; Seakwoo Lee; Chiaki Nakata; Shukti Chakravarti
Extracellular matrix lumican promotes bacterial phagocytosis, and Lum-/- mice show increased Pseudomonas aeruginosa lung infection severity.
Abdel Rahim A Hamad; Sophia Uddin; Kristin Arcara; Thomas Donner
The potential of Fas ligand (apoptosis-inducing molecule) as an unconventional therapeutic target in type 1 diabetes.

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All Publications

2013: Hanjuan Shao; Abdel Rahim A Hamad; Chiaki Nakata; Sherri-Gae Scott; Shukti Chakravarti
Extracellular matrix protein lumican promotes clearance and resolution of Pseudomonas aeruginosa keratitis in a mouse model.
PloS one 2013;8(1):e54765.
2012: Hanjuan Shao; Shoujun Chen; Sherri Gae-Scott; Abdel Rahim A Hamad; Seakwoo Lee; Chiaki Nakata; Shukti Chakravarti
Extracellular matrix lumican promotes bacterial phagocytosis, and Lum-/- mice show increased Pseudomonas aeruginosa lung infection severity.
The Journal of biological chemistry 2012;287(43):35860-72.
2012: Abdel Rahim A Hamad; Sophia Uddin; Kristin Arcara; Thomas Donner
The potential of Fas ligand (apoptosis-inducing molecule) as an unconventional therapeutic target in type 1 diabetes.
Frontiers in immunology 2012;3():196.
2012: Kristin Lohr; Abdel Rahim A Hamad; Seakwoo Lee; Feng Wu; Hardik Sardana; David L Huso; Shukti Chakravarti
Extracellular matrix protein lumican regulates inflammation in a mouse model of colitis.
Inflammatory bowel diseases 2012;18(1):143-51.
2011: Zuoxiang Xiao; Hideo Yagita; Patrizio Caturegli; Shukti Chakravarti; Rachel Gutfreund; Yanfei Huang; Chunfa Jie; Hiroaki Kimura; Andrew Marshall; Abdiaziz S Mohamood; Chiaki Nakata; Jonathan P Schneck; Sophia Uddin; Karl L Womer; Abdel Rahim A Hamad
Inhibition of Fas ligand in NOD mice unmasks a protective role for IL-10 against insulitis development.
The American journal of pathology 2011;179(2):725-32.
2011: Gang Jee Ko; Hye Ryoun Jang; Yanfei Huang; Karl L Womer; Manchang Liu; Elizabeth Higbee; Zuoxiang Xiao; Hideo Yagita; Lorraine C Racusen; Abdel Rahim A Hamad; Hamid Rabb
Blocking Fas ligand on leukocytes attenuates kidney ischemia-reperfusion injury.
Journal of the American Society of Nephrology : JASN 2011;22(4):732-42.
2011: Albert S Jun; Leslie Cope; Caroline Speck; Xiaojun Feng; Seakwoo Lee; Huan Meng; Abdel Rahim A Hamad; Shukti Chakravarti
Subnormal cytokine profile in the tear fluid of keratoconus patients.
PloS one 2011;6(1):e16437.
2010: Abdel Rahim A Hamad
Analysis of gene profile, steady state proliferation and apoptosis of double-negative T cells in the periphery and gut epithelium provides new insights into the biological functions of the Fas pathway.
Immunologic research 2010;47(1-3):134-42.
2009: Seakwoo Lee; Kyle Bowrin; Abdel Rahim A Hamad; Shukti Chakravarti
Extracellular matrix lumican deposited on the surface of neutrophils promotes migration by binding to beta2 integrin.
The Journal of biological chemistry 2009;284(35):23662-9.
2009: Ki-Jong Rhee; Shaoguang Wu; Xinqun Wu; David L Huso; Baktiar O Karim; Augusto A. Franco-Mora; Shervin Rabizadeh; Jonathan E Golub; Lauren E Mathews; Jai Shin; Ryan Sartor; Douglas Golenbock; Abdel Rahim A Hamad; Christine M Gan; Franck Housseau; Cynthia L Sears
Induction of persistent colitis by a human commensal, enterotoxigenic Bacteroides fragilis, in wild-type C57BL/6 mice.
Infection and immunity 2009;77(4):1708-18.
2008: Abdiaziz S Mohamood; Dylan Bargatze; Zuoxiang Xiao; Chunfa Jie; Hideo Yagita; DAWN RUBEN; Julie Watson; Shukti Chakravarti; Jonathan P Schneck; Abdel Rahim A Hamad
Fas-mediated apoptosis regulates the composition of peripheral alphabeta T cell repertoire by constitutively purging out double negative T cells.
PloS one 2008;3(10):e3465.
2008: X Ma; Michael Torbenson; Abdel Rahim A Hamad; Mark J Soloski; Zhiping Li
High-fat diet modulates non-CD1d-restricted natural killer T cells and regulatory T cells in mouse colon and exacerbates experimental colitis.
Clinical and experimental immunology 2008;151(1):130-8.
2007: Xiong Ma; Jing Hua; Abdiaziz R Mohamood; Abdel Rahim A Hamad; Rajani Ravi; Zhiping Li
A high-fat diet and regulatory T cells influence susceptibility to endotoxin-induced liver injury.
Hepatology (Baltimore, Md.) 2007;46(5):1519-29.
2007: Abdiaziz S Mohamood; Mehmet L Guler; Zuoxiang Xiao; Dongfeng Zheng; Allan Hess; Yi Wang; Hideo Yagita; Jonathan P Schneck; Abdel Rahim A Hamad
Protection from autoimmune diabetes and T-cell lymphoproliferation induced by FasL mutation are differentially regulated and can be uncoupled pharmacologically.
The American journal of pathology 2007;171(1):97-106.
2006: Abdiaziz S Mohamood; Crystal J Trujillo; Dongfeng Zheng; Chunfa Jie; Francisco Martinez Murillo; Jonathan P Schneck; Abdel Rahim A Hamad
Gld mutation of Fas ligand increases the frequency and up-regulates cell survival genes in CD25+CD4+ TR cells.
International immunology 2006;18(8):1265-77.
2003: Abdel Rahim A Hamad; Abdiaziz S Mohamood; Crystal J Trujillo; Ching-Tai Huang; Emily Yuan; Jonathan P Schneck
B220+ double-negative T cells suppress polyclonal T cell activation by a Fas-independent mechanism that involves inhibition of IL-2 production.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(5):2421-6.
2001: Abdel Rahim A Hamad; Jonathan P Schneck
Antigen-induced T cell death is regulated by CD4 expression.
International reviews of immunology 2001;20(5):535-46.
2001: Abdel Rahim A Hamad; A Srikrishnan; P Mirmonsef; C P Broeren; Carl H June; Drew M Pardoll; Jonathan P Schneck
Lack of coreceptor allows survival of chronically stimulated double-negative alpha/beta T cells: implications for autoimmunity.
The Journal of experimental medicine 2001;193(10):1113-21.
1999: MS Lebowitz; SM O'Herrin; Abdel Rahim A Hamad; Tarek M Fahmy; D Marguet; N C Barnes; Drew M Pardoll; Joan G Bieler; Jonathan P Schneck
Soluble, high-affinity dimers of T-cell receptors and class II major histocompatibility complexes: biochemical probes for analysis and modulation of immune responses.
Cellular immunology 1999;192(2):175-84.
1998: Abdel Rahim A Hamad; SM O'Herrin; MS Lebowitz; A Srikrishnan; Joan G Bieler; Jonathan P Schneck; Drew M Pardoll
Potent T cell activation with dimeric peptide-major histocompatibility complex class II ligand: the role of CD4 coreceptor.
The Journal of experimental medicine 1998;188(9):1633-40.
1997: Abdel Rahim A Hamad; Philippa Marrack; John W Kappler
Transcytosis of staphylococcal superantigen toxins.
The Journal of experimental medicine 1997;185(8):1447-54.
1995: C H Kirkpatrick; Abdel Rahim A Hamad; L C Morton
Murine transfer factors: dose-response relationships and routes of administration.
Cellular immunology 1995;164(2):203-6.
1994: Abdel Rahim A Hamad; A Herman; Philippa Marrack; John W Kappler
Monoclonal antibodies defining functional sites on the toxin superantigen staphylococcal enterotoxin B.
The Journal of experimental medicine 1994;180(2):615-21.