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Ernest Hamel

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TOP 3
Matthew D Cullen; Taradas Sarkar; Ernest Hamel; Tracy L Hartman; Karen M Watson; Robert W Buckheit; Christophe Pannecouque; Erik De Clercq; Mark Cushman
Inhibition of tubulin polymerization by select alkenyldiarylmethanes.
Allison B Edsall; Arasambattu K Mohanakrishnan; Donglai Yang; Phillip E Fanwick; Ernest Hamel; Arthur D Hanson; Gregory E Agoston; Mark Cushman
Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
Fanrong Mu; Ernest Hamel; Debbie J Lee; Donald E Pryor; Mark Cushman
Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A.

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2008: Matthew D Cullen; Taradas Sarkar; Ernest Hamel; Tracy L Hartman; Karen M Watson; Robert W Buckheit; Christophe Pannecouque; Erik De Clercq; Mark Cushman
Inhibition of tubulin polymerization by select alkenyldiarylmethanes.
Bioorganic & medicinal chemistry letters 2008;18(2):469-73.
2004: Allison B Edsall; Arasambattu K Mohanakrishnan; Donglai Yang; Phillip E Fanwick; Ernest Hamel; Arthur D Hanson; Gregory E Agoston; Mark Cushman
Effects of altering the electronics of 2-methoxyestradiol on cell proliferation, on cytotoxicity in human cancer cell cultures, and on tubulin polymerization.
Journal of medicinal chemistry 2004;47(21):5126-39.
2003: Fanrong Mu; Ernest Hamel; Debbie J Lee; Donald E Pryor; Mark Cushman
Synthesis, anticancer activity, and inhibition of tubulin polymerization by conformationally restricted analogues of lavendustin A.
Journal of medicinal chemistry 2003;46(9):1670-82.
2002: Fanrong Mu; Debbie J Lee; Donald E Pryor; Ernest Hamel; Mark Cushman
Synthesis and investigation of conformationally restricted analogues of lavendustin A as cytotoxic inhibitors of tubulin polymerization.
Journal of medicinal chemistry 2002;45(21):4774-85.
2002: Mark Cushman; Arasambattu K Mohanakrishnan; Melinda G Hollingshead; Ernest Hamel
The effect of exchanging various substituents at the 2-position of 2-methoxyestradiol on cytotoxicity in human cancer cell cultures and inhibition of tubulin polymerization.
Journal of medicinal chemistry 2002;45(21):4748-54.
2000: Z Wang; Donglai Yang; Arasambattu K Mohanakrishnan; Phillip E Fanwick; P Nampoothiri; Ernest Hamel; Mark Cushman
Synthesis of B-ring homologated estradiol analogues that modulate tubulin polymerization and microtubule stability.
Journal of medicinal chemistry 2000;43(12):2419-29.
1997: Mark Cushman; H M He; J A Katzenellenbogen; R K Varma; Ernest Hamel; C M Lin; S Ram; Y P Sachdeva
Synthesis of analogs of 2-methoxyestradiol with enhanced inhibitory effects on tubulin polymerization and cancer cell growth.
Journal of medicinal chemistry 1997;40(15):2323-34.