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Carlene Hamilton

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Ruth M Mackenzie; William H Miller; Michael P Murphy; Ian P Salt; Jane A Dymott; Carlene A Hamilton; Hagar A Ibrahim; Angela Logan; Andrea Degasperi; Christian Delles; Anna F Dominiczak
Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes.
Christian Delles; Jane A Dymott; Ulf Neisius; J Paul Rocchiccioli; Gavin J Bryce; María U Moreno; David M Carty; Geoffrey A Berg; Carlene A Hamilton; Anna F Dominiczak
Reduced LDL-cholesterol levels in patients with coronary artery disease are paralleled by improved endothelial function: An observational study in patients from 2003 and 2007.
Delyth Graham; Ngan N Huynh; Carlene A Hamilton; Elisabeth Beattie; Robin A J Smith; Helena M Cochemé; Michael P Murphy; Anna F Dominiczak
Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy.

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All Publications

2013: Ruth M Mackenzie; William H Miller; Michael P Murphy; Ian P Salt; Jane A Dymott; Carlene A Hamilton; Hagar A Ibrahim; Angela Logan; Andrea Degasperi; Christian Delles; Anna F Dominiczak
Mitochondrial reactive oxygen species enhance AMP-activated protein kinase activation in the endothelium of patients with coronary artery disease and diabetes.
Clinical science (London, England : 1979) 2013;124(6):403-11.
2010: Christian Delles; Jane A Dymott; Ulf Neisius; J Paul Rocchiccioli; Gavin J Bryce; María U Moreno; David M Carty; Geoffrey A Berg; Carlene A Hamilton; Anna F Dominiczak
Reduced LDL-cholesterol levels in patients with coronary artery disease are paralleled by improved endothelial function: An observational study in patients from 2003 and 2007.
Atherosclerosis 2010;211(1):271-7.
2009: Delyth Graham; Ngan N Huynh; Carlene A Hamilton; Elisabeth Beattie; Robin A J Smith; Helena M Cochemé; Michael P Murphy; Anna F Dominiczak
Mitochondria-targeted antioxidant MitoQ10 improves endothelial function and attenuates cardiac hypertrophy.
Hypertension 2009;54(2):322-8.
2009: Han Hui Caline Koh-Tan; Delyth Graham; Carlene A Hamilton; Gavin Nicoll; Laura Fields; Martin W McBride; Barbara Young; Anna F Dominiczak
Renal and vascular glutathione S-transferase mu is not affected by pharmacological intervention to reduce systolic blood pressure.
Journal of hypertension 2009;27(8):1575-84.
2008: Christian Delles; Lukas U Zimmerli; David J McGrane; Caline Hh Koh-Tan; Vivek L Pathi; Alan J McKay; Tracey Steedman; Henry J Dargie; Carlene A Hamilton; Anna F Dominiczak
Vascular stiffness is related to superoxide generation in the vessel wall.
Journal of hypertension 2008;26(5):946-55.
2006: Carlene A Hamilton; Samantha Groves; Hilary V O Carswell; M Julia Brosnan; Delyth Graham; Anna F Dominiczak
Estrogen treatment enhances nitric oxide bioavailability in normotensive but not hypertensive rats.
American journal of hypertension 2006;19(8):859-66.
2006: Sammy Al-Benna; Carlene A Hamilton; John D McClure; Paul N Rogers; Geoffrey A Berg; Ian Ford; Christian Delles; Anna F Dominiczak
Low-density lipoprotein cholesterol determines oxidative stress and endothelial dysfunction in saphenous veins from patients with coronary artery disease.
Arteriosclerosis, thrombosis, and vascular biology 2006;26(1):218-23.
2005: Anna F Dominiczak; Delyth Graham; Martin W McBride; Nick J R Brain; Wai Kwong Lee; Fadi J Charchar; Maciej Tomaszewski; Christian Delles; Carlene A Hamilton
Corcoran Lecture. Cardiovascular genomics and oxidative stress.
Hypertension 2005;45(4):636-42.
2005: Martin W McBride; M Julia Brosnan; Joanne Mathers; Lesley I McLellan; William H Miller; Delyth Graham; Neil Hanlon; Carlene A Hamilton; James M Polke; Wai K Lee; Anna F Dominiczak
Reduction of Gstm1 expression in the stroke-prone spontaneously hypertension rat contributes to increased oxidative stress.
Hypertension 2005;45(4):786-92.
2005: Roland W McCallum; Carlene A Hamilton; Delyth Graham; Emma Jardine; John Mc Connell; Anna F Dominiczak
Vascular responses to IGF-I and insulin are impaired in aortae of hypertensive rats.
Journal of hypertension 2005;23(2):351-8.
2004: Carlene A Hamilton; William H Miller; Sammy Al-Benna; M Julia Brosnan; Russell D Drummond; Martin W McBride; Anna F Dominiczak
Strategies to reduce oxidative stress in cardiovascular disease.
Clinical science (London, England : 1979) 2004;106(3):219-34.
2004: Daniel Antier; Hilary V O Carswell; M Julia Brosnan; Carlene A Hamilton; I Mhairi Macrae; S Groves; Emma Jardine; John L Reid; Anna E Dominiczak
Increased levels of superoxide in brains from old female rats.
Free radical research 2004;38(2):177-83.
2002: Carlene A Hamilton; M Julia Brosnan; Sammy Al-Benna; Geoffrey Berg; Anna F Dominiczak
NAD(P)H oxidase inhibition improves endothelial function in rat and human blood vessels.
Hypertension 2002;40(5):755-62.
2002: Carlene A Hamilton; G O'Dowd; L McIntosh; G Berg; J Butler; VL Pathi; R Williams; John L Reid; Anna F Dominiczak
Vasorelaxant properties of isolated human radial arteries: comparison with internal mammary arteries.
Atherosclerosis 2002;160(2):345-53.
2002: M Julia Brosnan; Carlene A Hamilton; Delyth Graham; Craig A Lygate; Emma Jardine; Anna F Dominiczak
Irbesartan lowers superoxide levels and increases nitric oxide bioavailability in blood vessels from spontaneously hypertensive stroke-prone rats.
Journal of hypertension 2002;20(2):281-6.
2002: Jerome Fennell; M Julia Brosnan; A J Frater; Carlene A Hamilton; MY Alexander; Stuart A Nicklin; D D Heistad; Andrew H Baker; Anna F Dominiczak
Adenovirus-mediated overexpression of extracellular superoxide dismutase improves endothelial dysfunction in a rat model of hypertension.
Gene therapy 2002;9(2):110-7.
2001: Carlene A Hamilton; Allan R McPhaden; G Berg; VL Pathi; Anna F Dominiczak
Is hydrogen peroxide an EDHF in human radial arteries?
American journal of physiology. Heart and circulatory physiology 2001;280(6):H2451-5.
2001: A J MacKay; Carlene A Hamilton; K McArthur; G Berg; Anne-Isabelle Tropeano; Pierre Boutouyrie; John L Reid; Anna F Dominiczak
Radial artery hypertrophy occurs in coronary atherosclerosis and is independent of blood pressure.
Clinical science (London, England : 1979) 2001;100(5):509-16.
2001: C Berry; M Julia Brosnan; Jerome Fennell; Carlene A Hamilton; Anna F Dominiczak
Oxidative stress and vascular damage in hypertension.
Current opinion in nephrology and hypertension 2001;10(2):247-55.
2001: Carlene A Hamilton; M Julia Brosnan; M Mcintyre; Delyth Graham; Anna F Dominiczak
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.
Hypertension 2001;37(2 Pt 2):529-34.
2000: MY Alexander; M Julia Brosnan; Carlene A Hamilton; Jerome Fennell; E C Beattie; Emma Jardine; D D Heistad; Anna F Dominiczak
Gene transfer of endothelial nitric oxide synthase but not Cu/Zn superoxide dismutase restores nitric oxide availability in the SHRSP.
Cardiovascular research 2000;47(3):609-17.
2000: C Berry; Carlene A Hamilton; M Julia Brosnan; F G Magill; Geoffrey A Berg; john mcmurray; Anna F Dominiczak
Investigation into the sources of superoxide in human blood vessels: angiotensin II increases superoxide production in human internal mammary arteries.
Circulation 2000;101(18):2206-12.
1999: MY Alexander; M Julia Brosnan; Carlene A Hamilton; Paul F Downie; AM Devlin; Fiona J Dowell; William Martin; HM Prentice; T O'Brien; Anna F Dominiczak
Gene transfer of endothelial nitric oxide synthase improves nitric oxide-dependent endothelial function in a hypertensive rat model.
Cardiovascular research 1999;43(3):798-807.
1999: S Kerr; M Julia Brosnan; M Mcintyre; John L Reid; Anna F Dominiczak; Carlene A Hamilton
Superoxide anion production is increased in a model of genetic hypertension: role of the endothelium.
Hypertension 1999;33(6):1353-8.
1999: Carlene A Hamilton; G Berg; K McArthur; John L Reid; Anna F Dominiczak
Does potassium channel opening contribute to endothelium-dependent relaxation in human internal thoracic artery?
Clinical science (London, England : 1979) 1999;96(6):631-8.
1999: Carlene A Hamilton; R Williams; VL Pathi; G Berg; K McArthur; Allan R McPhaden; John L Reid; Anna F Dominiczak
Pharmacological characterisation of endothelium-dependent relaxation in human radial artery: comparison with internal thoracic artery.
Cardiovascular research 1999;42(1):214-23.
1999: Niall H Anderson; AM Devlin; Delyth Graham; James J Morton; Carlene A Hamilton; John L Reid; N J Schork; Anna F Dominiczak
Telemetry for cardiovascular monitoring in a pharmacological study: new approaches to data analysis.
Hypertension 1999;33(1 Pt 2):248-55.
1998: Carlene A Hamilton; C A Howie; Emma Jardine; John L Reid
Endothelium dependent and independent relaxation of aortic rings from Watanabe heritable hyperlipidemic rabbits after exposure to free radical generating system.
Free radical research 1998;28(3):251-7.
1998: AM Devlin; M Julia Brosnan; Delyth Graham; James J Morton; Allan R McPhaden; M Mcintyre; Carlene A Hamilton; John L Reid; Anna F Dominiczak
Vascular smooth muscle cell polyploidy and cardiomyocyte hypertrophy due to chronic NOS inhibition in vivo.
The American journal of physiology 1998;274(1 Pt 2):H52-9.
1997: M McIntyre; Carlene A Hamilton; D D Rees; John L Reid; A F Dominiczak
Sex differences in the abundance of endothelial nitric oxide in a model of genetic hypertension.
Hypertension 1997;30(6):1517-24.
1997: Carlene A Hamilton; G Berg; M Mcintyre; Allan R McPhaden; John L Reid; Anna F Dominiczak
Effects of nitric oxide and superoxide on relaxation in human artery and vein.
Atherosclerosis 1997;133(1):77-86.
1997: Anna F Dominiczak; AM Devlin; M J Brosnan; Niall H Anderson; D Graham; J S Clark; Allan R McPhaden; Carlene A Hamilton; John L Reid
Left ventricular hypertrophy and arterial blood pressure in experimental models of hypertension.
Advances in experimental medicine and biology 1997;432():23-33.
1997: Carlene A Hamilton
Low-density lipoprotein and oxidised low-density lipoprotein: their role in the development of atherosclerosis.
Pharmacology & therapeutics 1997;74(1):55-72.
1996: Fiona J Dowell; Carlene A Hamilton; John L Reid
Effects of manipulation of dietary cholesterol on the function of the thoracic aorta from New Zealand white rabbits.
Journal of cardiovascular pharmacology 1996;27(2):235-9.
1995: G F Nixon; N J Pyne; R M Wadsworth; Carlene A Hamilton; John L Reid
Pertussis toxin sensitive endothelin-1 coupling to inositol phosphate formation via a GTP-binding protein: comparison in SHR and WKY cultured aortic smooth muscle cells.
Clinical and experimental hypertension (New York, N.Y. : 1993) 1995;17(3):507-22.
1995: N Thorin-Trescases; Carlene A Hamilton; John L Reid; K L McPherson; E Jardine; G Berg; D Bohr; A F Dominiczak
Inducible L-arginine/nitric oxide pathway in human internal mammary artery and saphenous vein.
The American journal of physiology 1995;268(3 Pt 2):H1122-32.
1995: AM Devlin; J F Gordon; A O Davidson; James S Clark; Carlene A Hamilton; James J Morton; A M Campbell; John L Reid; Anna F Dominiczak
The effects of perindopril on vascular smooth muscle polyploidy in stroke-prone spontaneously hypertensive rats.
Journal of hypertension 1995;13(2):211-8.
1994: N Thorin-Trescases; Carlene A Hamilton; E Jardine; John L Reid
Signal transduction mechanisms of the vasoconstriction in hypertension.
European journal of pharmacology 1994;268(2):199-207.
1994: Carlene A Hamilton; E Thorin; J McCulloch; Marek Dominiczak; John L Reid
Chronic exposure of bovine aortic endothelial cells to native and oxidized LDL modifies phosphatidylinositol metabolism.
Atherosclerosis 1994;107(1):55-63.
1994: E Thorin; Carlene A Hamilton; Marek Dominiczak; John L Reid
Chronic exposure of cultured bovine endothelial cells to oxidized LDL abolishes prostacyclin release.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1994;14(3):453-9.
1994: E G Godfrey; J Stewart; H J Dargie; John L Reid; M Dominiczak; Carlene A Hamilton; J McMurray
Effects of ACE inhibitors on oxidation of human low density lipoprotein.
British journal of clinical pharmacology 1994;37(1):63-6.
1993: Fiona J Dowell; Carlene A Hamilton; john mcmurray; John L Reid
Effects of a xanthine oxidase/hypoxanthine free radical and reactive oxygen species generating system on endothelial function in New Zealand white rabbit aortic rings.
Journal of cardiovascular pharmacology 1993;22(6):792-7.
1993: N Thorin-Trescases; W R Dimitri; A F Dominiczak; Carlene A Hamilton; John L Reid
Vasorelaxant properties of isolated human internal mammary arteries and saphenous veins: comparative effects of milrinone and sodium nitroprusside.
Journal of cardiovascular pharmacology 1993;22(5):673-80.
1993: G F Nixon; Carlene A Hamilton; R M Wadsworth; John L Reid
Comparison of endothelin-1 and noradrenaline stimulated inositol phosphate formation in cultured aortic smooth muscle cells from spontaneously hypertensive and Wistar Kyoto rats.
Blood pressure 1993;2(3):221-7.
1992: Carlene A Hamilton
Adrenergic and nonadrenergic effects of imidazoline and related antihypertensive drugs in the brain and periphery.
American journal of hypertension 1992;5(4 Pt 2):58S-63S.
1992: Carlene A Hamilton
The role of imidazoline receptors in blood pressure regulation.
Pharmacology & therapeutics 1992;54(3):231-48.
1992: Carlene A Hamilton; M A Yakubu; C A Howie; John L Reid
Do centrally-acting antihypertensive drugs act at non-adrenergic as well as alpha-2 adrenoceptor sites?
Clinical and experimental hypertension. Part A, Theory and practice 1992;14(5):815-35.
1991: Carlene A Hamilton; M A Yakubu; E Jardine; John L Reid
Imidazole binding sites in rabbit kidney and forebrain membranes.
Journal of autonomic pharmacology 1991;11(4):277-83.
1990: G F Nixon; Carlene A Hamilton; R M Wadsworth; John L Reid
Inositol phosphate formation in arterial smooth muscle from rabbits with perinephritis hypertension.
Journal of hypertension 1990;8(12):1155-60.
1990: A J MacGilchrist; N M Deighton; Carlene A Hamilton; John L Reid
Binding studies of platelet alpha 2- and lymphocyte beta 2-adrenoceptors in patients with cirrhosis.
British journal of clinical pharmacology 1990;30(4):644-7.
1990: Carlene A Hamilton; M A Yakubu; C A Howie; E Jardine; John L Reid
Desensitization and down-regulation of brain alpha 2-adrenoceptors by centrally acting antihypertensive drugs.
British journal of clinical pharmacology 1990;30 Suppl 1():131S-134S.
1989: N M Deighton; Carlene A Hamilton; C A Howie; John L Reid
Effects of short-term exposure to noradrenaline and adrenaline on adrenoceptor responses.
European journal of pharmacology 1989;169(1):95-101.
1989: Y T Huang; Carlene A Hamilton; John L Reid
Endothelin stimulates phosphatidylinositol hydrolysis in rat vascular smooth muscles.
Journal of hypertension 1989;7(9):703-5.
1989: M S Elfellah; Carlene A Hamilton; W McIntosh; S M Barr; C Howie; John L Reid
Skeletal muscle beta 2-adrenoreceptors and the effect of adrenergic drugs on plasma potassium in perinephritis hypertension in rabbits.
Journal of autonomic pharmacology 1989;9(2):113-8.
1989: S M Barr; Carlene A Hamilton; John L Reid
Platelet cytosolic free calcium before and after antihypertensive treatment in perinephritis hypertension of the rabbit.
Clinical and experimental hypertension. Part A, Theory and practice 1989;11(4):633-48.
1988: N M Deighton; A D Brown; Carlene A Hamilton; John L Reid
Regulation of adrenergic receptor number following chronic noradrenaline infusion in the rabbit.
Naunyn-Schmiedeberg's archives of pharmacology 1988;338(5):517-22.
1988: M A Yakubu; Carlene A Hamilton; C A Howie; John L Reid
Idazoxan and brain alpha 2-adrenoceptors in the rabbit.
Brain research 1988;463(2):289-95.
1988: N M Deighton; Carlene A Hamilton; Richard jones; John L Reid
The effects of chronic administration of adrenaline on the function and number of adrenoceptors in the rabbit.
Journal of cardiovascular pharmacology 1988;12(3):332-7.
1988: Carlene A Hamilton; John L Reid
Alpha 1-adrenoceptor desensitisation.
European journal of pharmacology 1988;152(1-2):179-83.
1988: Carlene A Hamilton; C A Howie; John L Reid
Desensitization of vascular and platelet alpha 2-adrenoceptors in rabbits with perinephritis hypertension.
Journal of hypertension 1988;6(4):277-82.
1988: Carlene A Hamilton; John L Reid; M A Yakubu
[3H]yohimbine and [3H]idazoxan bind to different sites on rabbit forebrain and kidney membranes.
European journal of pharmacology 1988;146(2-3):345-8.
1986: Richard jones; M Giembcyz; Carlene A Hamilton; I W Rodger; K Whyte; N Deighton; H L Elliott; John L Reid
Desensitization of platelet alpha 2-adrenoceptors after short term infusions of adrenoceptor agonist in man.
Clinical science (London, England : 1979) 1986;70(2):147-53.