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James Hammond

Research Profile

Chemicals & Drugs

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Publications

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Sumeeta Warraich; Derek Bj Bone; Doo-Sup Choi; S Jeffrey Dixon; Maria Drangova; David W Holdsworth; Hisataka Ii; Diana Quinonez; Cheryle A Séguin; James R Hammond
Loss of equilibrative nucleoside transporter 1 in mice leads to progressive ectopic mineralization of spinal tissues resembling diffuse idiopathic skeletal hyperostosis in humans.
Jamie S Park; Scott J Hughes; Frances K M Cunningham; James R Hammond
Identification of cysteines involved in the effects of methanethiosulfonate reagents on human equilibrative nucleoside transporter 1.
Derek B J Bone; Doo-Sup Choi; Imogen R Coe; James R Hammond
Nucleoside/nucleobase transport and metabolism by microvascular endothelial cells isolated from ENT1-/- mice.

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All Publications

2013: Sumeeta Warraich; Derek Bj Bone; Doo-Sup Choi; S Jeffrey Dixon; Maria Drangova; David W Holdsworth; Hisataka Ii; Diana Quinonez; Cheryle A Séguin; James R Hammond
Loss of equilibrative nucleoside transporter 1 in mice leads to progressive ectopic mineralization of spinal tissues resembling diffuse idiopathic skeletal hyperostosis in humans.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2013;28(5):1135-49.
2011: Jamie S Park; Scott J Hughes; Frances K M Cunningham; James R Hammond
Identification of cysteines involved in the effects of methanethiosulfonate reagents on human equilibrative nucleoside transporter 1.
Molecular pharmacology 2011;80(4):735-46.
2010: Derek B J Bone; Doo-Sup Choi; Imogen R Coe; James R Hammond
Nucleoside/nucleobase transport and metabolism by microvascular endothelial cells isolated from ENT1-/- mice.
American journal of physiology. Heart and circulatory physiology 2010;299(3):H847-56.
2008: Kevin R Robillard; Derek B J Bone; Jamie S Park; James R Hammond
Characterization of mENT1Delta11, a novel alternative splice variant of the mouse equilibrative nucleoside transporter 1.
Molecular pharmacology 2008;74(1):264-73.
2008: Kevin R Robillard; Derek B J Bone; James R Hammond
Hypoxanthine uptake and release by equilibrative nucleoside transporter 2 (ENT2) of rat microvascular endothelial cells.
Microvascular research 2008;75(3):351-7.
2007: Derek B J Bone; James R Hammond
Nucleoside and nucleobase transporters of primary human cardiac microvascular endothelial cells: characterization of a novel nucleobase transporter.
American journal of physiology. Heart and circulatory physiology 2007;293(6):H3325-32.
2007: Derek B J Bone; Kevin R Robillard; Meaghan Stolk; James R Hammond
Differential regulation of mouse equilibrative nucleoside transporter 1 (mENT1) splice variants by protein kinase CK2.
Molecular membrane biology 2007;24(4):294-303.
2005: Meaghan Stolk; Elizabeth Cooper; Greg Vilk; David W Litchfield; James R Hammond
Subtype-specific regulation of equilibrative nucleoside transporters by protein kinase CK2.
The Biochemical journal 2005;386(Pt 2):281-9.
2004: Richard G E Archer; Václav Pitelka; James R Hammond
Nucleoside transporter subtype expression and function in rat skeletal muscle microvascular endothelial cells.
British journal of pharmacology 2004;143(1):202-14.
2004: James R Hammond; Meaghan Stolk; Richard G E Archer; Kristy McConnell
Pharmacological analysis and molecular cloning of the canine equilibrative nucleoside transporter 1.
European journal of pharmacology 2004;491(1):9-19.
2004: James R Hammond; Richard G E Archer
Interaction of the novel adenosine uptake inhibitor 3-[1-(6,7-diethoxy-2-morpholinoquinazolin-4-yl)piperidin-4-yl]-1,6-dimethyl-2,4(1H,3H)-quinazolinedione hydrochloride (KF24345) with the es and ei subtypes of equilibrative nucleoside transporters.
The Journal of pharmacology and experimental therapeutics 2004;308(3):1083-93.
2002: Satyen Vyas; Badri Ahmadi; James R Hammond
Complex effects of sulfhydryl reagents on ligand interactions with nucleoside transporters: evidence for multiple populations of ENT1 transporters with differential sensitivities to N-ethylmaleimide.
Archives of biochemistry and biophysics 2002;403(1):92-102.
2001: P B Stathopulos; Xiangru Lu; J Shen; J A Scott; James R Hammond; D G McCormack; J Malcolm O Arnold; Qingping Feng
Increased L-arginine uptake and inducible nitric oxide synthase activity in aortas of rats with heart failure.
American journal of physiology. Heart and circulatory physiology 2001;280(2):H859-67.
2000: A Kiss; K Farah; J Kim; Robert J Garriock; Thomas A Drysdale; James R Hammond
Molecular cloning and functional characterization of inhibitor-sensitive (mENT1) and inhibitor-resistant (mENT2) equilibrative nucleoside transporters from mouse brain.
The Biochemical journal 2000;352 Pt 2():363-72.
2000: James R Hammond
Interaction of a series of draflazine analogues with equilibrative nucleoside transporters: species differences and transporter subtype selectivity.
Naunyn-Schmiedeberg's archives of pharmacology 2000;361(4):373-82.
1999: James R Hammond; S Lee; Peter J Ferguson
[3H]gemcitabine uptake by nucleoside transporters in a human head and neck squamous carcinoma cell line.
The Journal of pharmacology and experimental therapeutics 1999;288(3):1185-91.
1998: T Burke; S Lee; Peter J Ferguson; James R Hammond
Interaction of 2',2'-difluorodeoxycytidine (gemcitabine) and formycin B with the Na+-dependent and -independent nucleoside transporters of Ehrlich ascites tumor cells.
The Journal of pharmacology and experimental therapeutics 1998;286(3):1333-40.
1997: James R Hammond
Enhancement of the functional stability of solubilized nucleoside transporters by substrates and inhibitors.
Biochemical pharmacology 1997;53(5):623-9.
1996: James R Hammond; M Zarenda
Effect of detergents on ligand binding and translocation activities of solubilized/reconstituted nucleoside transporters.
Archives of biochemistry and biophysics 1996;332(2):313-22.
1995: K W Jones; James R Hammond
Characterization of nucleoside transport activity in rabbit cortical synaptosomes.
Canadian journal of physiology and pharmacology 1995;73(12):1733-41.
1994: James R Hammond
Functional reconstitution of pharmacologically distinct subtypes of nucleoside transporters in liposomal membranes.
The Journal of pharmacology and experimental therapeutics 1994;271(2):906-17.
1994: K W Jones; Rebecca Rylett; James R Hammond
Effect of cellular differentiation on nucleoside transport in human neuroblastoma cells.
Brain research 1994;660(1):104-12.
1993: K W Jones; James R Hammond
Interaction of the mioflazine derivative R75231 with the nucleoside transporter: evidence for positive cooperativity.
European journal of pharmacology 1993;246(2):97-104.
1992: James R Hammond
Differential uptake of [3H]guanosine by nucleoside transporter subtypes in Ehrlich ascites tumour cells.
The Biochemical journal 1992;287 ( Pt 2)():431-6.
1992: K W Jones; James R Hammond
Heterogeneity of [3H]dipyridamole binding to CNS membranes: correlation with [3H]nitrobenzylthioinosine binding and [3H]uridine influx studies.
Journal of neurochemistry 1992;59(4):1363-71.
1991: James R Hammond
Comparative pharmacology of the nitrobenzylthioguanosine-sensitive and -resistant nucleoside transport mechanisms of Ehrlich ascites tumor cells.
The Journal of pharmacology and experimental therapeutics 1991;259(2):799-807.
1991: James R Hammond
Kinetic analysis of ligand binding to the Ehrlich cell nucleoside transporter: pharmacological characterization of allosteric interactions with the [3H]nitrobenzylthioinosine binding site.
Molecular pharmacology 1991;39(6):771-9.
1991: James R Hammond
Effect of membrane lipid composition on the functional activity of a reconstituted nucleoside transporter derived from Ehrlich ascites cells.
Advances in experimental medicine and biology 1991;309A():423-6.