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Milton Hammond

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Shen Hong C; Ding Fa-Xiang; Deng Qiaolin; Wilsie Larissa C; Krsmanovic Mihajlo L; Taggart Andrew K; Carballo-Jane Ester; Ren Ning; Cai Tian-Quan; Wu Tsuei-Ju; Wu Kenneth K; Cheng Kang; Chen Qing; Wolff Michael S; Tong Xinchun; Holt Tom G; Waters M Gerard; Hammond Milton L; Tata James R; Colletti Steven L
Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats.
Shen Hong C; Ding Fa-Xiang; Singh Sheo B; Parthasarathy Gopalakrishnan; Soisson Stephen M; Ha Sookhee N; Chen Xun; Kodali Srinivas; Wang Jun; Dorso Karen; Tata James R; Hammond Milton L; Maccoss Malcolm; Colletti Steven L
Synthesis and biological evaluation of platensimycin analogs.
Shen Hong C; Taggart Andrew K P; Wilsie Larissa C; Waters M Gerard; Hammond Milton L; Tata James R; Colletti Steven L
Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A.

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All Publications

2009: Shen Hong C; Ding Fa-Xiang; Deng Qiaolin; Wilsie Larissa C; Krsmanovic Mihajlo L; Taggart Andrew K; Carballo-Jane Ester; Ren Ning; Cai Tian-Quan; Wu Tsuei-Ju; Wu Kenneth K; Cheng Kang; Chen Qing; Wolff Michael S; Tong Xinchun; Holt Tom G; Waters M Gerard; Hammond Milton L; Tata James R; Colletti Steven L
Discovery of novel tricyclic full agonists for the G-protein-coupled niacin receptor 109A with minimized flushing in rats.
Journal of medicinal chemistry 2009;52(8):2587-602.
2009: Shen Hong C; Ding Fa-Xiang; Singh Sheo B; Parthasarathy Gopalakrishnan; Soisson Stephen M; Ha Sookhee N; Chen Xun; Kodali Srinivas; Wang Jun; Dorso Karen; Tata James R; Hammond Milton L; Maccoss Malcolm; Colletti Steven L
Synthesis and biological evaluation of platensimycin analogs.
Bioorganic & medicinal chemistry letters 2009;19(6):1623-7.
2008: Shen Hong C; Taggart Andrew K P; Wilsie Larissa C; Waters M Gerard; Hammond Milton L; Tata James R; Colletti Steven L
Discovery of pyrazolopyrimidines as the first class of allosteric agonists for the high affinity nicotinic acid receptor GPR109A.
Bioorganic & medicinal chemistry letters 2008;18(18):4948-51.
2008: Ali Amjad; Balkovec James M; Greenlee Mark; Hammond Milton L; Rouen Greg; Taylor Gayle; Einstein Monica; Ge Lan; Harris Georgianna; Kelly Terri M; Mazur Paul; Pandit Shilpa; Santoro Joseph; Sitlani Ayesha; Wang Chuanlin; Williamson Joann; Forrest Michael J; Carballo-Jane Ester; Luell Silvi; Lowitz Karen; Visco Denise
Discovery of betamethasone 17alpha-carbamates as dissociated glucocorticoid receptor modulators in the rat.
Bioorganic & medicinal chemistry 2008;16(16):7535-42.
2008: Scafonas Angela; Reszka Alfred A; Kimmel Donald B; Hou Xiaoli Shirley; Su Qin; Birzin Elizabeth T; Kim Seongkon; Chen Helen Y; Tan Qiang; Roher Susan P; Dininno Frank; Hammond Milton L; Rodan Gideon A; Towler Dwight A; Schmidt Azriel
Agonist-like SERM effects on ERalpha-mediated repression of MMP1 promoter activity predict in vivo effects on bone and uterus.
The Journal of steroid biochemistry and molecular biology 2008;110(3-5):197-206.
2008: Raghavan Subharekha; Tria G Scott; Shen Hong C; Ding Fa-Xiang; Taggart Andrew K; Ren Ning; Wilsie Larrisa C; Krsmanovic Mihajlo L; Holt Tom G; Wolff Michael S; Waters M Gerard; Hammond Milton L; Tata James R; Colletti Steven L
Tetrahydro anthranilic acid as a surrogate for anthranilic acid: application to the discovery of potent niacin receptor agonists.
Bioorganic & medicinal chemistry letters 2008;18(11):3163-7.
2007: Shen Hong C; Szymonifka Michael J; Kharbanda Divya; Deng Qiaolin; Carballo-Jane Ester; Wu Kenneth K; Wu Tsuei-Ju; Cheng Kang; Ren Ning; Cai Tian-Quan; Taggart Andrew K; Wang Junying; Tong Xinchun; Waters M Gerard; Hammond Milton L; Tata James R; Colletti Steven L
Discovery of orally bioavailable and novel urea agonists of the high affinity niacin receptor GPR109A.
Bioorganic & medicinal chemistry letters 2007;17(24):6723-8.
2007: Shen Hong C; Ding Fa-Xiang; Luell Silvi; Forrest Michael J; Carballo-Jane Ester; Wu Kenneth K; Wu Tsuei-Ju; Cheng Kang; Wilsie Larissa C; Krsmanovic Mihajlo L; Taggart Andrew K; Ren Ning; Cai Tian-Quan; Deng Qiaolin; Chen Qing; Wang Junying; Wolff Michael S; Tong Xinchun; Holt Tom G; Waters M Gerard; Hammond Milton L; Tata James R; Colletti Steven L
Discovery of biaryl anthranilides as full agonists for the high affinity niacin receptor.
Journal of medicinal chemistry 2007;50(25):6303-6.
2007: Blizzard Timothy A; Gude Candido; Morgan Jerry D; Chan Wanda; Birzin Elizabeth T; Mojena Marina; Tudela Consuelo; Chen Fang; Knecht Kristin; Su Qin; Kraker Bryan; Mosley Ralph T; Holmes Mark A; Rohrer Susan P; Hammond Milton L
Androstene-3,5-dienes as ER-beta selective SERMs.
Bioorganic & medicinal chemistry letters 2007;17(22):6295-8.
2007: Thompson Christopher F; Quraishi Nazia; Ali Amjad; Mosley Ralph T; Tata James R; Hammond Milton L; Balkovec James M; Einstein Monica; Ge Lan; Harris Georgianna; Kelly Terri M; Mazur Paul; Pandit Shilpa; Santoro Joseph; Sitlani Ayesha; Wang Chuanlin; Williamson Joanne; Miller Douglas K; Yamin Ting-Ting D; Thompson Chris M; O'Neill Edward A; Zaller Dennis; Forrest Michael J; Carballo-Jane Ester; Luell Silvi
Novel glucocorticoids containing a 6,5-bicyclic core fused to a pyrazole ring: synthesis, in vitro profile, molecular modeling studies, and in vivo experiments.
Bioorganic & medicinal chemistry letters 2007;17(12):3354-61.
2007: Blizzard Timothy A; Gude Candido; Chan Wanda; Birzin Elizabeth T; Mojena Marina; Tudela Consuelo; Chen Fang; Knecht Kristin; Su Qin; Kraker Bryan; Holmes Mark A; Rohrer Susan P; Hammond Milton L
Bridged androstenediol analogs as ER-beta selective SERMs.
Bioorganic & medicinal chemistry letters 2007;17(10):2944-8.
2007: Dykstra Kevin D; Guo Liangqin; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Hayes Edward C; DaSilva Carolyn A; Pai Lee-Yuh; Mosley Ralph T; Kraker Bryan; Fitzgerald Paula M D; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 16: 2-Aryl indoles as highly subtype selective ligands for ERalpha.
Bioorganic & medicinal chemistry letters 2007;17(8):2322-8.
2006: Wildonger Kenneth J; Ratcliffe Ronald W; Mosley Ralph T; Hammond Milton L; Birzin Elizabeth T; Rohrer Susan P
Tetrahydrofluorenones with conformationally restricted side chains as selective estrogen receptor beta ligands.
Bioorganic & medicinal chemistry letters 2006;16(17):4462-6.
2006: Parker Dann L; Meng Dongfang; Ratcliffe Ronald W; Wilkening Robert R; Sperbeck Donald M; Greenlee Mark L; Colwell Lawrence F; Lambert Sherrie; Birzin Elizabeth T; Frisch Katalin; Rohrer Susan P; Nilsson Stefan; Thorsell Ann-Gerd; Hammond Milton L
Triazolo-tetrahydrofluorenones as selective estrogen receptor beta agonists.
Bioorganic & medicinal chemistry letters 2006;16(17):4652-6.
2006: Wilkening R R; Ratcliffe R W; Fried A K; Meng D; Sun W; Colwell L; Lambert S; Greenlee M; Nilsson S; Thorsell A; Mojena M; Tudela C; Frisch K; Chan W; Birzin E T; Rohrer S P; Hammond M L
Estrogen receptor beta-subtype selective tetrahydrofluorenones: use of a fused pyrazole as a phenol bioisostere.
Bioorganic & medicinal chemistry letters 2006;16(15):3896-901.
2006: Wilkening R R; Ratcliffe R W; Tynebor E C; Wildonger K J; Fried A K; Hammond M L; Mosley R T; Fitzgerald P M D; Sharma N; McKeever B M; Nilsson S; Carlquist M; Thorsell A; Locco L; Katz R; Frisch K; Birzin E T; Wilkinson H A; Mitra S; Cai S; Hayes E C; Schaeffer J M; Rohrer S P
The discovery of tetrahydrofluorenones as a new class of estrogen receptor beta-subtype selective ligands.
Bioorganic & medicinal chemistry letters 2006;16(13):3489-94.
2006: Sun Wanying; Cama Lovji D; Birzin Elizabeth T; Warrier Sudha; Locco Louis; Mosley Ralph; Hammond Milton L; Rohrer Susan P
6H-Benzo[c]chromen-6-one derivatives as selective ERbeta agonists.
Bioorganic & medicinal chemistry letters 2006;16(6):1468-72.
2006: Lipfert Lorraine; Fisher John E; Wei Nan; Scafonas Angela; Su Qin; Yudkovitz Joel; Chen Fang; Warrier Sudha; Birzin Elizabeth T; Kim Seongkon; Chen Helen Y; Tan Qiang; Schmidt Azriel; Dininno Frank; Rohrer Susan P; Hammond Milton L; Rodan Gideon A; Freedman Leonard P; Reszka Alfred A
Antagonist-induced, activation function-2-independent estrogen receptor alpha phosphorylation.
Molecular endocrinology (Baltimore, Md.) 2006;20(3):516-33.
2006: Blizzard Timothy A; Gude Candido; Morgan Jerry D; Chan Wanda; Birzin Elizabeth T; Mojena Marina; Tudela Consuelo; Chen Fang; Knecht Kristin; Su Qin; Kraker Bryan; Mosley Ralph T; Holmes Mark A; Sharma Nandini; Fitzgerald Paula M D; Rohrer Susan P; Hammond Milton L
Androstenediol analogs as ER-beta-selective SERMs.
Bioorganic & medicinal chemistry letters 2006;16(4):834-8.
2005: Blizzard Timothy A; Morgan Jerry D; Chan Wanda; Birzin Elizabeth T; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; Mosley Ralph T; Yang Yi Tien; Rohrer Susan P; Dininno Frank; Hammond Milton L
Estrogen receptor ligands. Part 14: application of novel antagonist side chains to existing platforms.
Bioorganic & medicinal chemistry letters 2005;15(23):5124-8.
2005: Blizzard Timothy A; DiNinno Frank; Chen Helen Y; Kim Seongkon; Wu Jane Y; Chan Wanda; Birzin Elizabeth T; Yang Yi Tien; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 13: Dihydrobenzoxathiin SERAMs with an optimized antagonist side chain.
Bioorganic & medicinal chemistry letters 2005;15(17):3912-6.
2005: Smith Cameron J; Ali Amjad; Balkovec James M; Graham Donald W; Hammond Milton L; Patel Gool F; Rouen Gregory P; Smith Scott K; Tata James R; Einstein Monica; Ge Lan; Harris Georgianna S; Kelly Theresa M; Mazur Paul; Thompson Chris M; Wang Chuanlin F; Williamson Joanne M; Miller Douglas K; Pandit Shilpa; Santoro Joseph C; Sitlani Ayesha; Yamin Ting-Ting D; O'Neill Edward A; Zaller Dennis M; Carballo-Jane Ester; Forrest Michael J; Luell Silvi
Novel ketal ligands for the glucocorticoid receptor: in vitro and in vivo activity.
Bioorganic & medicinal chemistry letters 2005;15(11):2926-31.
2005: Zhang Zhoupeng; Chen Qing; Li Ying; Doss George A; Dean Brian J; Ngui Jason S; Silva Elipe Maria; Kim Seongkon; Wu Jane Y; Dininno Frank; Hammond Milton L; Stearns Ralph A; Evans David C; Baillie Thomas A; Tang Wei
In vitro bioactivation of dihydrobenzoxathiin selective estrogen receptor modulators by cytochrome P450 3A4 in human liver microsomes: formation of reactive iminium and quinone type metabolites.
Chemical research in toxicology 2005;18(4):675-85.
2005: Thompson Christopher F; Quraishi Nazia; Ali Amjad; Tata James R; Hammond Milton L; Balkovec James M; Einstein Monica; Ge Lan; Harris Georgianna; Kelly Theresa M; Mazur Paul; Pandit Shilpa; Santoro Joseph; Sitlani Ayesha; Wang Chuanlin; Williamson Joanne; Miller Douglas K; Yamin Ting-ting D; Thompson Chris M; O'Neill Edward A; Zaller Dennis; Forrest Michael J; Carballo-Jane Ester; Luell Silvi
Novel heterocyclic glucocorticoids: in vitro profile and in vivo efficacy.
Bioorganic & medicinal chemistry letters 2005;15(8):2163-7.
2005: Tan Qiang; Blizzard Timothy A; Morgan Jerry D; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; Warrier Sudha; Yudkovitz Joel; Wilkinson Hilary A; Sharma Nandini; Fitzgerald Paula M D; Li Susan; Colwell Lawrence; Fisher John E; Adamski Sharon; Reszka Alfred A; Kimmel Donald; DiNinno Frank; Rohrer Susan P; Freedman Leonard P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs.
Bioorganic & medicinal chemistry letters 2005;15(6):1675-81.
2005: Kim Seongkon; Wu Jane Y; Zhang Zhoupeng; Tang Wei; Doss George A; Dean Brian J; Dininno Frank; Hammond Milton L
Estrogen receptor ligands. 12. Synthesis of the major metabolites of an ERalpha-selective, dihydrobenzoxathiin antagonist for osteoporosis.
Organic letters 2005;7(3):411-4.
2005: Liu Jian; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Pai Lee-Yuh; Dasilva Carolyn; Hayes Edward C; Mosley Ralph T; Dininno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 11: Synthesis and activity of isochromans and isothiochromans.
Bioorganic & medicinal chemistry letters 2005;15(3):715-8.
2005: Blizzard Timothy A; Dininno Frank; Morgan Jerry D; Chen Helen Y; Wu Jane Y; Kim Seongkon; Chan Wanda; Birzin Elizabeth T; Yang Yi Tien; Pai Lee-Yuh; Fitzgerald Paula M D; Sharma Nandini; Li Ying; Zhang Zhoupeng; Hayes Edward C; Dasilva Carolyn A; Tang Wei; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers.
Bioorganic & medicinal chemistry letters 2005;15(1):107-13.
2004: Blizzard Timothy A; DiNinno Frank; Morgan Jerry D; Wu Jane Y; Chen Helen Y; Kim Seongkon; Chan Wanda; Birzin Elizabeth T; Yang Yi Tien; Pai Lee-Yuh; Zhang Zhoupeng; Hayes Edward C; DaSilva Carolyn A; Tang Wei; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 8: Dihydrobenzoxathiin SERAMs with heteroatom-substituted side chains.
Bioorganic & medicinal chemistry letters 2004;14(15):3865-8.
2004: Blizzard Timothy A; DiNinno Frank; Morgan Jerry D; Chen Helen Y; Wu Jane Y; Gude Candido; Kim Seongkon; Chan Wanda; Birzin Elizabeth T; Tien Yang Yi; Pai Lee-Yuh; Zhang Zhoupeng; Hayes Edward C; DaSilva Carolyn A; Tang Wei; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 7: Dihydrobenzoxathiin SERAMs with bicyclic amine side chains.
Bioorganic & medicinal chemistry letters 2004;14(15):3861-4.
2004: Tan Qiang; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 6: Synthesis and binding affinity of dihydrobenzodithiins.
Bioorganic & medicinal chemistry letters 2004;14(14):3753-5.
2004: Tan Qiang; Birzin Elizabeth T; Chan Wanda; Tien Yang Yi; Pai Lee-Yuh; Hayes Edward C; DaSilva Carolyn A; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 5: The SAR of dihydrobenzoxathiins containing modified basic side chains.
Bioorganic & medicinal chemistry letters 2004;14(14):3747-51.
2004: Hammond Milton L
Ertapenem: a Group 1 carbapenem with distinct antibacterial and pharmacological properties.
The Journal of antimicrobial chemotherapy 2004;53 Suppl 2():ii7-9.
2004: Kim Seongkon; Wu Jane; Chen Helen Y; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Colwell Lawrence; Li Susan; Dahllund Johanna; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 4: The SAR of the syn-dihydrobenzoxathiin SERAMs.
Bioorganic & medicinal chemistry letters 2004;14(11):2741-5.
2004: Ali Amjad; Thompson Christopher F; Balkovec James M; Graham Donald W; Hammond Milton L; Quraishi Nazia; Tata James R; Einstein Monica; Ge Lan; Harris Georgianna; Kelly Terri M; Mazur Paul; Pandit Shilpa; Santoro Joseph; Sitlani Ayesha; Wang Chuanlin; Williamson Joanne; Miller Douglas K; Thompson Chris M; Zaller Dennis M; Forrest Michael J; Carballo-Jane Ester; Luell Silvi
Novel N-arylpyrazolo[3,2-c]-based ligands for the glucocorticoid receptor: receptor binding and in vivo activity.
Journal of medicinal chemistry 2004;47(10):2441-52.
2004: Chen Helen Y; Kim Seongkon; Wu Jane Y; Birzin Elizabeth T; Chan Wanda; Yang Yi Tien; Dahllund Johanna; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 3: The SAR of dihydrobenzoxathiin SERMs.
Bioorganic & medicinal chemistry letters 2004;14(10):2551-4.
2004: Kim Seongkon; Wu Jane Y; Birzin Elizabeth T; Frisch Katalin; Chan Wanda; Pai Lee-Yuh; Yang Yi Tien; Mosley Ralph T; Fitzgerald Paula M D; Sharma Nandini; Dahllund Johanna; Thorsell Ann-Gerd; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. II. Discovery of benzoxathiins as potent, selective estrogen receptor alpha modulators.
Journal of medicinal chemistry 2004;47(9):2171-5.
2004: Chen Helen Y; Dykstra Kevin D; Birzin Elizabeth T; Frisch Katalin; Chan Wanda; Yang Yi T; Mosley Ralph T; DiNinno Frank; Rohrer Susan P; Schaeffer James M; Hammond Milton L
Estrogen receptor ligands. Part 1: The discovery of flavanoids with subtype selectivity.
Bioorganic & medicinal chemistry letters 2004;14(6):1417-21.
2004: Blizzard Timothy A; Mosley Ralph T; Birzin Elizabeth T; Chan Wanda; Hammond Milton L
Comparison of 2-phenylspiroindenes and 2-phenylspiroindenediones as estrogen receptor ligands--modeling and binding data don't agree!
Bioorganic & medicinal chemistry letters 2004;14(5):1317-21.
2003: Blizzard Timothy A; Morgan Jerry D; Mosley Ralph T; Birzin Elizabeth T; Frisch Katalin; Rohrer Susan P; Hammond Milton L
2-Phenylspiroindenes: a novel class of selective estrogen receptor modulators (SERMs).
Bioorganic & medicinal chemistry letters 2003;13(3):479-83.
2002: Chen Qing; Ngui Jason S; Doss George A; Wang Regina W; Cai Xiaoxin; DiNinno Frank P; Blizzard Timothy A; Hammond Milton L; Stearns Ralph A; Evans David C; Baillie Thomas A; Tang Wei
Cytochrome P450 3A4-mediated bioactivation of raloxifene: irreversible enzyme inhibition and thiol adduct formation.
Chemical research in toxicology 2002;15(7):907-14.
2002: Blizzard Timothy A; Kim Ronald M; Morgan Jerry D; Chang Jiang; Kohler Joyce; Kilburn Ruth; Chapman Kevin; Hammond Milton L
Antibacterial activity of G6-quaternary ammonium derivatives of a lipophilic vancomycin analogue.
Bioorganic & medicinal chemistry letters 2002;12(6):849-52.
2001: Toney J H; Hammond G G; Fitzgerald P M; Sharma N; Balkovec J M; Rouen G P; Olson S H; Hammond M L; Greenlee M L; Gao Y D
Succinic acids as potent inhibitors of plasmid-borne IMP-1 metallo-beta-lactamase.
The Journal of biological chemistry 2001;276(34):31913-8.
1999: Greenlee M L; Laub J B; Rouen G P; DiNinno F; Hammond M L; Huber J L; Sundelof J G; Hammond G G
Dicationic 2-fluorenonylcarbapenems: potent anti-MRS agents with improved solubility and pharmacokinetic properties.
Bioorganic & medicinal chemistry letters 1999;9(22):3225-30.
1999: Greenlee M L; Laub J B; Balkovec J M; Hammond M L; Hammond G G; Pompliano D L; Epstein-Toney J H
Synthesis and SAR of thioester and thiol inhibitors of IMP-1 metallo-beta-lactamase.
Bioorganic & medicinal chemistry letters 1999;9(17):2549-54.
1999: Ratcliffe R W; Wilkening R R; Wildonger K J; Waddell S T; Santorelli G M; Parker D L; Morgan J D; Blizzard T A; Hammond M L; Heck J V; Huber J; Kohler J; Dorso K L; St Rose E; Sundelof J G; May W J; Hammond G G
Synthesis and properties of 2-(naphthosultamyl)methyl-carbapenems with potent anti-MRSA activity: discovery of L-786,392.
Bioorganic & medicinal chemistry letters 1999;9(5):679-84.
1999: Wilkening R R; Ratcliffe R W; Wildonger K J; Cama L D; Dykstra K D; DiNinno F P; Blizzard T A; Hammond M L; Heck J V; Dorso K L; St Rose E; Kohler J; Hammond G G
Synthesis and activity of 2-(sulfonamido)methyl-carbapenems: discovery of a novel, anti-MRSA 1,8-naphthosultam pharmacophore.
Bioorganic & medicinal chemistry letters 1999;9(5):673-8.
1999: Rosen H; Hajdu R; Silver L; Kropp H; Dorso K; Kohler J; Sundelof J G; Huber J; Hammond G G; Jackson J J; Gill C J; Thompson R; Pelak B A; Epstein-Toney J H; Lankas G; Wilkening R R; Wildonger K J; Blizzard T A; DiNinno F P; Ratcliffe R W; Heck J V; Kozarich J W; Hammond M L
Reduced immunotoxicity and preservation of antibacterial activity in a releasable side-chain carbapenem antibiotic.
Science (New York, N.Y.) 1999;283(5402):703-6.
1994: Bouffard F A; Zambias R A; Dropinski J F; Balkovec J M; Hammond M L; Abruzzo G K; Bartizal K F; Marrinan J A; Kurtz M B; McFadden D C
Synthesis and antifungal activity of novel cationic pneumocandin B(o) derivatives.
Journal of medicinal chemistry 1994;37(2):222-5.
1992: Zambias R A; Hammond M L; Heck J V; Bartizal K; Trainor C; Abruzzo G; Schmatz D M; Nollstadt K M
Preparation and structure-activity relationships of simplified analogues of the antifungal agent cilofungin: a total synthesis approach.
Journal of medicinal chemistry 1992;35(15):2843-55.
1992: Balkovec J M; Black R M; Hammond M L; Heck J V; Zambias R A; Abruzzo G; Bartizal K; Kropp H; Trainor C; Schwartz R E
Synthesis, stability, and biological evaluation of water-soluble prodrugs of a new echinocandin lipopeptide. Discovery of a potential clinical agent for the treatment of systemic candidiasis and Pneumocystis carinii pneumonia (PCP).
Journal of medicinal chemistry 1992;35(1):194-8.
1990: Hammond M L; Zambias R A; Chang M N; Jensen N P; McDonald J; Thompson K; Boulton D A; Kopka I E; Hand K M; Opas E E
Antioxidant-based inhibitors of leukotriene biosynthesis. The discovery of 6-[1-[2-(hydroxymethyl)phenyl]-1-propen-3-yl]-2,3-dihydro-5- benzofuranol, a potent topical antiinflammatory agent.
Journal of medicinal chemistry 1990;33(3):908-18.
1989: Hammond M L; Kopka I E; Zambias R A; Caldwell C G; Boger J; Baker F; Bach T; Luell S; MacIntyre D E
2,3-Dihydro-5-benzofuranols as antioxidant-based inhibitors of leukotriene biosynthesis.
Journal of medicinal chemistry 1989;32(5):1006-20.

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Milton Hammond

Research Profile (preview)

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Anatomy

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Publications

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