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Marian Hamshere

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Elaine K Green; Detelina Grozeva; Marian Hamshere; Ian Richard Jones; Lesley Jones; Peter McGuffin; J L Moran; Michael C O'Donovan; Michael J Owen; S Purcell; E Russell; P Sklar; Anne Farmer; Liz Forty; Katherine Gordon-Smith; Nick Craddock
Association at SYNE1 in both bipolar disorder and recurrent major depression.
Marian Hamshere; Peter Holmans; Lisa A Jones; Geraldine M McCarthy; Peter McGuffin; Kieran C Murphy; Nadine Norton; Michael C O'Donovan; Michael J Owen; Robert D Sanders; Hywel J Williams; Nigel M Williams; Stanley Zammit; Nicholas Craddock; MY Gray; Alastair G Cardno
Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia.
Marian Hamshere; Peter Holmans; Ian Richard Jones; Lesley Jones; George Kirov; Peter McGuffin; Andrew McQuillin; Valentina Moskvina; Michael C O'Donovan; Michael J Owen; S Purcell; P Sklar; D St Clair; A H Young; Anne Farmer; Ian Nicol Ferrier; Elaine K Green; Detelina Grozeva; H Gurling; N Bass; Nick Craddock
Polygenic dissection of the bipolar phenotype.

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All Publications

2013: Elaine K Green; Detelina Grozeva; Marian Hamshere; Ian Richard Jones; Lesley Jones; Peter McGuffin; J L Moran; Michael C O'Donovan; Michael J Owen; S Purcell; E Russell; P Sklar; Anne Farmer; Liz Forty; Katherine Gordon-Smith; Nick Craddock
Association at SYNE1 in both bipolar disorder and recurrent major depression.
Molecular psychiatry 2013;18(5):614-7.
2011: Marian Hamshere; Peter Holmans; Lisa A Jones; Geraldine M McCarthy; Peter McGuffin; Kieran C Murphy; Nadine Norton; Michael C O'Donovan; Michael J Owen; Robert D Sanders; Hywel J Williams; Nigel M Williams; Stanley Zammit; Nicholas Craddock; MY Gray; Alastair G Cardno
Phenotype evaluation and genomewide linkage study of clinical variables in schizophrenia.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2011;156B(8):929-40.
2011: Marian Hamshere; Peter Holmans; Ian Richard Jones; Lesley Jones; George Kirov; Peter McGuffin; Andrew McQuillin; Valentina Moskvina; Michael C O'Donovan; Michael J Owen; S Purcell; P Sklar; D St Clair; A H Young; Anne Farmer; Ian Nicol Ferrier; Elaine K Green; Detelina Grozeva; H Gurling; N Bass; Nick Craddock
Polygenic dissection of the bipolar phenotype.
The British journal of psychiatry : the journal of mental science 2011;198(4):284-8.
2010: Roy H Perlis; Jie Huang; Shaun Purcell; Maurizio Fava; A John Rush; Patrick F Sullivan; Steven P Hamilton; Francis McMajon; Thomas G. Schulze; Thomas Schulze; James B Potash; Peter P Zandi; Virginia L Willour; Brenda W Penninx; Dorret I Boomsma; Nicole Vogelzangs; Christel M Middeldorp; Marcella Rietschel; Markus Nöthen; Sven Cichon; Hugh Gurling; Nick Bass; Andrew McQuillin; Marian Hamshere; Nick Craddock; Pamela Sklar; Jordan W Smoller
Genome-wide association study of suicide attempts in mood disorder patients.
The American journal of psychiatry 2010;167(12):1499-507.
2010: Elaine K Green; Detelina Grozeva; Valentina Moskvina; Marian Hamshere; Ian R Jones; Lisa Jones; Liz Forty; Sian Caesar; Katherine Gordon-Smith; Christine Fraser; Ellie Russell; David St Clair; Allan H Young; Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
Variation at the GABAA receptor gene, Rho 1 (GABRR1) associated with susceptibility to bipolar schizoaffective disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2010;153B(7):1347-9.
2010: Elaine K Green; Detelina Grozeva; Ian Jones; Lesley Jones; George Kirov; Sian Caesar; Katherine Gordon-Smith; C Fraser; Liz Forty; E Russell; Marian Hamshere; Valentina Moskvina; Ivan Nikolov; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia.
Molecular psychiatry 2010;15(10):1016-22.
2010: Arianna Di Florio; Marian Hamshere; Liz Forty; Elaine K Green; Detelina Grozeva; Ian Jones; Sian Caesar; Christine Fraser; Katherine Gordon-Smith; Lisa Jones; Nick Craddock; Daniel J Smith
Affective temperaments across the bipolar-unipolar spectrum: examination of the TEMPS-A in 927 patients and controls.
Journal of affective disorders 2010;123(1-3):42-51.
2010: Nick Craddock; Lesley Jones; I R Jones; George Kirov; Elaine K Green; Detelina Grozeva; Valentina Moskvina; Ivan Nikolov; Marian Hamshere; D Vukcevic; Sian Caesar; Katherine Gordon-Smith; C Fraser; E Russell; Nadine Norton; Gerome Breen; D St Clair; David A Collier; A H Young; Ian Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; P Donnelly; Michael J Owen; Michael C O'Donovan
Strong genetic evidence for a selective influence of GABAA receptors on a component of the bipolar disorder phenotype.
Molecular psychiatry 2010;15(2):146-53.
2009: Marian Hamshere; Elaine K Green; I R Jones; Lesley Jones; Valentina Moskvina; George Kirov; Detelina Grozeva; Ivan Nikolov; D Vukcevic; Sian Caesar; Katherine Gordon-Smith; C Fraser; E Russell; Gerome Breen; D St Clair; D A Collier; A H Young; Ian Nicol Ferrier; Anne Farmer; Peter McGuffin; Peter Holmans; Michael J Owen; Michael C O'Donovan; Nick Craddock
Genetic utility of broadly defined bipolar schizoaffective disorder as a diagnostic concept.
The British journal of psychiatry : the journal of mental science 2009;195(1):23-9.
2009: Amy W Butler; Mandy Y M Ng; Marian Hamshere; Paola Forabosco; Richard Wroe; Ammar Al-Chalabi; Cathryn M Lewis; John F Powell
Meta-analysis of linkage studies for Alzheimer's disease--a web resource.
Neurobiology of aging 2009;30(7):1037-47.
2009: Marian Hamshere; Katherine Gordon-Smith; Liz Forty; Lisa Jones; Sian Caesar; Christine Fraser; Sally Hyde; John Tredget; George Kirov; Ian Jones; Nick Craddock; Daniel J Smith
Age-at-onset in bipolar-I disorder: mixture analysis of 1369 cases identifies three distinct clinical sub-groups.
Journal of affective disorders 2009;116(1-2):23-9.
2007: Marian Hamshere; Peter Holmans; Dimitrios Avramopoulos; Susan S Bassett; Deborah Blacker; Lars Bertram; Howard Wiener; Nan Rochberg; Rudolph E Tanzi; Amanda Myers; Fabienne Wavrant-De Vrièze; Rodney Go; Daniele Fallin; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen
Genome-wide linkage analysis of 723 affected relative pairs with late-onset Alzheimer's disease.
Human molecular genetics 2007;16(22):2703-12.
2007: Paul Hollingworth; Marian Hamshere; Peter Holmans; Michael C O'Donovan; Rebecca Sims; John Powell; Simon Lovestone; Amanda Myers; FW DeVrieze; John Hardy; Alison Goate; Michael J Owen; Julie Williams
Increased familial risk and genomewide significant linkage for Alzheimer's disease with psychosis.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2007;144B(7):841-8.
2007: Ian Jones; Marian Hamshere; Jeanne-Marrie Nangle; Philip Bennett; Elaine Green; Jessica Heron; Ricardo Segurado; David Lambert; Peter Holmans; Aiden Corvin; Michael J Owen; Lisa Jones; Michael Gill; Nick Craddock
Bipolar affective puerperal psychosis: genome-wide significant evidence for linkage to chromosome 16.
The American journal of psychiatry 2007;164(7):1099-104.
2007: Beate Glaser; Ivan Nikolov; Daniel Chubb; Marian Hamshere; Ricardo Segurado; Valentina Moskvina; Peter Holmans
Analyses of single marker and pairwise effects of candidate loci for rheumatoid arthritis using logistic regression and random forests.
BMC proceedings 2007;1 Suppl 1():S54.
2007: Ricardo Segurado; Marian Hamshere; Beate Glaser; Ivan Nikolov; Valentina Moskvina; Peter Holmans
Combining linkage data sets for meta-analysis and mega-analysis: the GAW15 rheumatoid arthritis data set.
BMC proceedings 2007;1 Suppl 1():S104.
2007: Marian Hamshere; Ricardo Segurado; Valentina Moskvina; Ivan Nikolov; Beate Glaser; Peter Holmans
Large-scale linkage analysis of 1302 affected relative pairs with rheumatoid arthritis.
BMC proceedings 2007;1 Suppl 1():S100.
2007: Mona Kaleem; A Zhao; Marian Hamshere; Amanda Myers
Identification of a novel valosin-containing protein polymorphism in late-onset Alzheimer's disease.
Neuro-degenerative diseases 2007;4(5):376-81.
2006: Paul Hollingworth; Marian Hamshere; Valentina Moskvina; Kimberley Dowzell; Pamela J Moore; Catherine Foy; Nicola Archer; Aoibhinn Lynch; Simon Lovestone; Carol Brayne; David C Rubinsztein; Brian A Lawlor; Mike Gill; Michael J Owen; Julie Williams
Four components describe behavioral symptoms in 1,120 individuals with late-onset Alzheimer's disease.
Journal of the American Geriatrics Society 2006;54(9):1348-54.
2006: Marian Hamshere; Nigel M Williams; Nadine Norton; Hywel Williams; Alastair G Cardno; Stanley Zammit; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; G Jones; Peter Holmans; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genome wide significant linkage in schizophrenia conditioning on occurrence of depressive episodes.
Journal of medical genetics 2006;43(7):563-7.
2006: Nigel M Williams; Elaine K Green; Stuart Macgregor; Sarah Dwyer; Nadine Norton; Hywel Williams; Rachel Raybould; Detelina Grozeva; Marian Hamshere; Stanley Zammit; Lisa Jones; Alastair G Cardno; George Kirov; Ian Jones; Michael C O'Donovan; Michael J Owen; Nick Craddock
Variation at the DAOA/G30 locus influences susceptibility to major mood episodes but not psychosis in schizophrenia and bipolar disorder.
Archives of general psychiatry 2006;63(4):366-73.
2005: Marian Hamshere; Philip Bennett; Nigel Williams; Ricardo Segurado; Alastair G Cardno; Nadine Norton; David Lambert; Hywel Williams; George Kirov; Aiden Corvin; Peter Holmans; Lisa Jones; Ian Jones; Michael Gill; Michael C O'Donovan; Michael J Owen; Nick Craddock
Genomewide linkage scan in schizoaffective disorder: significant evidence for linkage at 1q42 close to DISC1, and suggestive evidence at 22q11 and 19p13.
Archives of general psychiatry 2005;62(10):1081-8.
2005: David Lambert; Fiona Middle; Marian Hamshere; Ricardo Segurado; Rachel Raybould; Aiden Corvin; Elaine Green; E O'Mahony; Ivan Nikolov; T Mulcahy; S Haque; S Bort; Philip Bennett; Nadine Norton; Michael J Owen; George Kirov; Corinne Lendon; Lesley Jones; Ian Jones; Peter Holmans; Michael Gill; Nick Craddock
Stage 2 of the Wellcome Trust UK-Irish bipolar affective disorder sibling-pair genome screen: evidence for linkage on chromosomes 6q16-q21, 4q12-q21, 9p21, 10p14-p12 and 18q22.
Molecular psychiatry 2005;10(9):831-41.
2005: Petra Nowotny; Anthony L Hinrichs; Scott Smemo; John S K Kauwe; Taylor Maxwell; Peter Holmans; Marian Hamshere; Darko Turic; Luke Jehu; Paul Hollingworth; Pamela Moore; Leslie Bryden; Amanda Myers; Lisa M Doil; Kristina M Tacey; Alison M Gibson; Ian G McKeith; Robert H Perry; Christopher M Morris; Leon J Thal; John C Morris; Michael C O'Donovan; Simon Lovestone; Andrew Grupe; John Hardy; Michael J Owen; Julie Williams; Alison Goate
Association studies between risk for late-onset Alzheimer's disease and variants in insulin degrading enzyme.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;136B(1):62-8.
2005: Elaine K Green; Rachel Raybould; Stuart Macgregor; Katherine Gordon-Smith; Jessica Heron; Sally Hyde; Detelina Grozeva; Marian Hamshere; Nigel Williams; Michael J Owen; Michael C O'Donovan; Lisa Jones; Ian Jones; George Kirov; Nick Craddock
Operation of the schizophrenia susceptibility gene, neuregulin 1, across traditional diagnostic boundaries to increase risk for bipolar disorder.
Archives of general psychiatry 2005;62(6):642-8.
2005: Peter Holmans; Marian Hamshere; Paul Hollingworth; Frances Rice; Nigel Tunstall; Sue Jones; Pamela Moore; Fabienne Wavrant DeVrieze; Amanda Myers; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Michael O'Donovan; Lesley Jones; John Hardy; Alison Goate; Simon Lovestone; Michael J Owen; Julie Williams
Genome screen for loci influencing age at onset and rate of decline in late onset Alzheimer's disease.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2005;135B(1):24-32.
2004: Amanda Myers; Helen Marshall; Peter Holmans; Danielle Compton; Richard Crook; adrian mander; Petra Nowotny; Scott Smemo; Melanie Dunstan; Luke Jehu; Jen C Wang; Marian Hamshere; John C Morris; Joanne Norton; Sumi Chakraventy; Nigel Tunstall; Simon Lovestone; Ronald C. Petersen; Michael O'Donovan; Lesley Jones; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Variation in the urokinase-plasminogen activator gene does not explain the chromosome 10 linkage signal for late onset AD.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2004;124B(1):29-37.
2003: Nigel M Williams; Nadine Norton; Hywel Williams; Birgit Ekholm; Marian Hamshere; Y Lindblom; Kodavali V Chowdari; Alastair G Cardno; Stanley Zammit; Lisa Anne Jones; Kieran C Murphy; Robert D Sanders; G McCarthy; MY Gray; G Jones; Peter Holmans; Vishwajit L Nimgaonkar; R Adolfson; Urban Osby; L Terenius; Göran C Sedvall; Michael C O'Donovan; Michael J Owen
A systematic genomewide linkage study in 353 sib pairs with schizophrenia.
American journal of human genetics 2003;73(6):1355-67.
2003: Kate Langley; Antony Payton; Marian Hamshere; Helen M Pay; Deborah C Lawson; Darko Turic; W E R Ollier; Jane Worthington; Michael J Owen; Michael C O'Donovan; Anita Thapar
No evidence of association of two 5HT transporter gene polymorphisms and attention deficit hyperactivity disorder.
Psychiatric genetics 2003;13(2):107-10.
2003: Darko Turic; L Robinson; M Duke; Derek W Morris; V Webb; Marian Hamshere; Charis Milham; Elizabeth Hopkin; K Pound; S Fernando; A Grierson; M Easton; Nigel Williams; Marianne B M van den Bree; R Chowdhury; J Gruen; J Stevenson; Michael Krawczak; Michael J Owen; Michael C O'Donovan; Julie Williams
Linkage disequilibrium mapping provides further evidence of a gene for reading disability on chromosome 6p21.3-22.
Molecular psychiatry 2003;8(2):176-85.
2003: Deborah C Lawson; Darko Turic; Kate Langley; Helen M Pay; Catherine F Govan; Nadine Norton; Marian Hamshere; Michael J Owen; Michael C O'Donovan; Anita Thapar
Association analysis of monoamine oxidase A and attention deficit hyperactivity disorder.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2003;116B(1):84-9.
2002: Amanda Myers; Fabienne Wavrant De-Vrieze; Peter Holmans; Marian Hamshere; Richard Crook; Danielle Compton; Helen Marshall; David Meyer; Shantia Shears; Jeremy Booth; Dzanan Ramic; Heather Knowles; John C Morris; Nigel Williams; Nadine Norton; Richard Abraham; Pat Kehoe; Hywel Williams; Varuni Rudrasingham; Frances Rice; Peter Giles; Nigel Tunstall; Lesley Jones; Simon Lovestone; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Full genome screen for Alzheimer disease: stage II analysis.
American journal of medical genetics 2002;114(2):235-44.
2002: Nigel M Williams; Gillian Spurlock; Nadine Norton; Hywel J Williams; Marian Hamshere; Michael Krawczak; George Kirov; Ivan Nikolov; Lyudmila Georgieva; Sue Jones; Alastair G Cardno; Michael C O'Donovan; Michael J Owen
Mutation screening and LD mapping in the VCFS deleted region of chromosome 22q11 in schizophrenia using a novel DNA pooling approach.
Molecular psychiatry 2002;7(10):1092-100.
2002: A West; Kate Langley; Marian Hamshere; Lindsey Kent; Nick Craddock; Michael J Owen; Michael O'Donovan; Anita Thapar
Evidence to suggest biased phenotypes in children with Attention Deficit Hyperactivity Disorder from completely ascertained trios.
Molecular psychiatry 2002;7(9):962-6.
2002: R J Anney; Mark I Rees; E Bryan; Gillian Spurlock; Nigel Williams; Nadine Norton; Hywel Williams; Alastair G Cardno; Stanley Zammit; Sue Jones; G Jones; Bastiaan Hoogendoorn; Kaye Smith; Marian Hamshere; S Coleman; Carol Guy; Michael C O'Donovan; Michael J Owen; Paul R Buckland
Characterisation, mutation detection, and association analysis of alternative promoters and 5' UTRs of the human dopamine D3 receptor gene in schizophrenia.
Molecular psychiatry 2002;7(5):493-502.
2001: Richard Abraham; Amanda Myers; Fabienne Wavrant DeVrieze; Marian Hamshere; Hollie V Thomas; Helen Marshall; Danielle Compton; Gillian Spurlock; Darko Turic; Bastiaan Hoogendoorn; Jennifer M Kwon; Ronald C. Petersen; Eric G Tangalos; J Norton; John C Morris; Ross Bullock; D Liolitsa; Simon Lovestone; John Hardy; Alison Goate; Michael O'Donovan; Julie Williams; Michael J Owen; Lesley Jones
Substantial linkage disequilibrium across the insulin-degrading enzyme locus but no association with late-onset Alzheimer's disease.
Human genetics 2001;109(6):646-52.
2001: Gaynor Jones; Stanley Zammit; Nadine Norton; Marian Hamshere; S J Jones; Charis Milham; Robert D Sanders; Geraldine M McCarthy; Lisa Anne Jones; Alastair G Cardno; Marion Gray; Kieran C Murphy; Michael J Owen
Aggressive behaviour in patients with schizophrenia is associated with catechol-O-methyltransferase genotype.
The British journal of psychiatry : the journal of mental science 2001;179():351-5.
2001: Alastair G Cardno; Peter Holmans; Mark I Rees; Lisa Anne Jones; Geraldine M McCarthy; Marian Hamshere; Nigel M Williams; Nadine Norton; Hywel J Williams; Iain Fenton; Kieran C Murphy; Robert D Sanders; MY Gray; Michael C O'Donovan; Peter McGuffin; Michael J Owen
A genomewide linkage study of age at onset in schizophrenia.
American journal of medical genetics 2001;105(5):439-45.
2000: Amanda Myers; Peter Holmans; Helen Marshall; J Kwon; David Meyer; Dzanan Ramic; Shantia Shears; Jeremy Booth; FW DeVrieze; Richard Crook; Marian Hamshere; Richard Abraham; Nigel Tunstall; Frances Rice; S Carty; S Lillystone; Pat Kehoe; Varuni Rudrasingham; Lesley Jones; Simon Lovestone; Jordi Perez-Tur; Julie Williams; Michael J Owen; John Hardy; Alison Goate
Susceptibility locus for Alzheimer's disease on chromosome 10.
Science (New York, N.Y.) 2000;290(5500):2304-5.
2000: Bastiaan Hoogendoorn; Nadine Norton; George Kirov; Nigel Williams; Marian Hamshere; Gillian Spurlock; J Austin; M K Stephens; Paul R Buckland; Michael J Owen; Michael C O'Donovan
Cheap, accurate and rapid allele frequency estimation of single nucleotide polymorphisms by primer extension and DHPLC in DNA pools.
Human genetics 2000;107(5):488-93.
2000: Derek W Morris; L Robinson; Darko Turic; M Duke; V Webb; Charis Milham; Elizabeth Hopkin; K Pound; S Fernando; M Easton; Marian Hamshere; Nigel Williams; Peter McGuffin; J Stevenson; Michael Krawczak; Michael J Owen; Michael C O'Donovan; Julie Williams
Family-based association mapping provides evidence for a gene for reading disability on chromosome 15q.
Human molecular genetics 2000;9(5):843-8.