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Ah-Reum Han

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Li Li; Hartmut Derendorf; Reginald F Frye; Ah-Reum Han; A Douglas Kinghorn; Veronika Butterweck
Pharmacokinetic properties of pure xanthones in comparison to a mangosteen fruit extract in rats.
Won-Jun Shon; Kwang-Shik Bae; Seung-Ho Baek; Ah-Reum Han; Kee-Yeon Kum; Woo-Cheol Lee
Effects of calcium phosphate endodontic sealers on the behavior of human periodontal ligament fibroblasts and MG63 osteoblast-like cells.
Ah-Reum Han; Byung-Gee Kim; Eunji Kim; EJ Kim; Dong Gun Lee; So Ra Lee; Je Won Park; Sung Ryeol Park; Pramod B Shinde; Young Ji Yoo; Yeon Hee Ban; Jaeyong Cho; Yeo Joon Yoon
Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities.

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All Publications

2013: Li Li; Hartmut Derendorf; Reginald F Frye; Ah-Reum Han; A Douglas Kinghorn; Veronika Butterweck
Pharmacokinetic properties of pure xanthones in comparison to a mangosteen fruit extract in rats.
Planta medica 2013;79(8):646-53.
2012: Won-Jun Shon; Kwang-Shik Bae; Seung-Ho Baek; Ah-Reum Han; Kee-Yeon Kum; Woo-Cheol Lee
Effects of calcium phosphate endodontic sealers on the behavior of human periodontal ligament fibroblasts and MG63 osteoblast-like cells.
Journal of biomedical materials research. Part B, Applied biomaterials 2012;100(8):2141-7.
2012: Ah-Reum Han; Byung-Gee Kim; Eunji Kim; EJ Kim; Dong Gun Lee; So Ra Lee; Je Won Park; Sung Ryeol Park; Pramod B Shinde; Young Ji Yoo; Yeon Hee Ban; Jaeyong Cho; Yeo Joon Yoon
Engineered biosynthesis of glycosylated derivatives of narbomycin and evaluation of their antibacterial activities.
Applied microbiology and biotechnology 2012;93(3):1147-56.
2011: Sung Ryeol Park; Mi Sun Ahn; Ah-Reum Han; Je Won Park; Yeo Joon Yoon
Enhanced flavonoid production in Streptomyces venezuelae via metabolic engineering.
Journal of microbiology and biotechnology 2011;21(11):1143-6.
2011: Je Won Park; Sung Ryeol Park; Jae Kyung Sohng; Young Ji Yoo; Yeon Hee Ban; Ah-Reum Han; Dooil Kim; Eun Ji Kim; Eui Min Kim; Keshav Kumar Nepal; Yeo Joon Yoon
Discovery of parallel pathways of kanamycin biosynthesis allows antibiotic manipulation.
Nature chemical biology 2011;7(11):843-52.
2011: Joo-Won Nam; Ah-Reum Han; Ga-Young Kang; Dongho Lee; Yun-Sil Lee; Eun-Kyoung Seo
Diarylheptanoids from the seeds of Alpinia katsumadai as heat shock factor 1 inducers.
Journal of natural products 2011;74(10):2109-15.
2011: Won Seok Jung; Eunji Kim; Eun Ji Kim; Je Won Park; Sung Ryeol Park; Young Ji Yoo; Yeon Hee Ban; Ah-Reum Han; Yeo Joon Yoon
A combined approach of classical mutagenesis and rational metabolic engineering improves rapamycin biosynthesis and provides insights into methylmalonyl-CoA precursor supply pathway in Streptomyces hygroscopicus ATCC 29253.
Applied microbiology and biotechnology 2011;91(5):1389-97.
2011: Ah-Reum Han; Byung-Gee Kim; Eunji Kim; Eun Ji Kim; Mi Kyeong Lee; Je Won Park; Jae Kyung Sohng; Young Ji Yoo; Yeon Hee Ban; Yeo Joon Yoon
Development of a Streptomyces venezuelae-based combinatorial biosynthetic system for the production of glycosylated derivatives of doxorubicin and its biosynthetic intermediates.
Applied and environmental microbiology 2011;77(14):4912-23.
2011: Ah-Reum Han; Byung-Gee Kim; Dong-Myung Kim; Eun Yeol Lee; Je Won Park; Sung Ryeol Park; Yeo Joon Yoon
Biosynthesis of glycosylated derivatives of tylosin in Streptomyces venezuelae.
Journal of microbiology and biotechnology 2011;21(6):613-6.
2011: Je Won Park; Sung Ryeol Park; Ah-Reum Han; Yeon-Hee Ban; Young Ji Yoo; Eun Ji Kim; Eunji Kim; Yeo Joon Yoon
Microbial transformation of trichostatin A to 2,3-dihydrotrichostatin A.
Journal of natural products 2011;74(5):1272-4.
2011: Li Li; Isabelle Brunner; Ah-Reum Han; Matthias Hamburger; Alan Douglas Kinghorn; Reginald Frye; Veronika Butterweck
Pharmacokinetics of α-mangostin in rats after intravenous and oral application.
Molecular nutrition & food research 2011;55 Suppl 1():S67-74.
2011: Je Won Park; Sung Ryeol Park; Ah-Reum Han; Yeon Hee Ban; Young Ji Yoo; Eunji Kim; Beom Seok Kim; Jae Kyung Sohng; Yeo Joon Yoon
Characterization and identification of pradimicin analogs from Actinomadura hibisca using liquid chromatography-tandem mass spectrometry.
Journal of chromatography. A 2011;1218(16):2284-91.
2011: Je Won Park; Sung Ryeol Park; Ah-Reum Han; Yeon-Hee Ban; Young Ji Yoo; Eun Ji Kim; Eunji Kim; Yeo Joon Yoon
Generation of reduced macrolide analogs by regio-specific biotransformation.
The Journal of antibiotics 2011;64(1):155-7.
2010: Je Won Park; Sung Ryeol Park; Ah-Reum Han; Yeon Hee Ban; Young Ji Yoo; Eun Ji Kim; Yeo Joon Yoon
The nebramycin aminoglycoside profiles of Streptomyces tenebrarius and their characterization using an integrated liquid chromatography-electrospray ionization-tandem mass spectrometric analysis.
Analytica chimica acta 2010;661(1):76-84.
2010: Sung Ryeol Park; Ah-Reum Han; Yeon-Hee Ban; Young Ji Yoo; Eun Ji Kim; Yeo Joon Yoon
Genetic engineering of macrolide biosynthesis: past advances, current state, and future prospects.
Applied microbiology and biotechnology 2010;85(5):1227-39.
2009: Ah-Reum Han; Jeong-Ah Kim; Daniel D Lantvit; Leonardus B S Kardono; Soedarsono Riswan; Heebyung Chai; Esperanza J Carcache de Blanco; Norman R Farnsworth; Steven M Swanson; A Douglas Kinghorn
Cytotoxic xanthone constituents of the stem bark of Garcinia mangostana (mangosteen).
Journal of natural products 2009;72(11):2028-31.
2009: Hyejung Lee; Ah-Reum Han; Yeunhee Kim; S H Choi; Eunjung Ko; N Y Lee; J H Jeong; Sung-Hoon Kim; Hyunsu Bae
A new compound, 1H,8H-pyrano[3,4-c]pyran-1,8-dione, suppresses airway epithelial cell inflammatory responses in a murine model of asthma.
International journal of immunopathology and pharmacology 2009;22(3):591-603.
2009: Sung Ryeol Park; Jin A Yoon; Ji Hye Paik; Je Won Park; Won Seok Jung; Yeon-Hee Ban; Eun Ji Kim; Young Ji Yoo; Ah-Reum Han; Yeo Joon Yoon
Engineering of plant-specific phenylpropanoids biosynthesis in Streptomyces venezuelae.
Journal of biotechnology 2009;141(3-4):181-8.
2009: Soo Yeon Chung; Ah-Reum Han; Min Kyung Sung; Ho Jin Jung; Joo-Won Nam; Eun-Kyoung Seo; Hwa Jeong Lee
Potent modulation of P-glycoprotein activity by naturally occurring phenylbutenoids from Zingiber cassumunar.
Phytotherapy research : PTR 2009;23(4):472-6.
2009: Su-Hyun Song; Hye-Young Min; Ah-Reum Han; Joo-Won Nam; Eun-Kyoung Seo
Suppression of inducible nitric oxide synthase by (-)-isoeleutherin from the bulbs of Eleutherine americana through the regulation of NF-kappaB activity.
International immunopharmacology 2009;9(3):298-302.
2008: Je Won Park; Hong-Se Oh; Won Seok Jung; Sung Ryeol Park; Ah-Reum Han; Yeon-Hee Ban; Eun Ji Kim; Han-Young Kang; Yeo Joon Yoon
Exploiting the natural metabolic diversity of Streptomyces venezuelae to generate unusual reduced macrolides.
Chemical communications (Cambridge, England) 2008;(44):5782-4.
2008: Sung Ryeol Park; Je Won Park; Won Seok Jung; Ah-Reum Han; Yeon-Hee Ban; Eun Ji Kim; Jae Kyung Sohng; Sang Jun Sim; Yeo Joon Yoon
Heterologous production of epothilones B and D in Streptomyces venezuelae.
Applied microbiology and biotechnology 2008;81(1):109-17.
2008: Ah-Reum Han; Seong-Ju Hwang
Soft-chemical synthesis of nanometer-thick carbon-coated titania: effect of carbon-coating on the photocatalytic activity of TiO2.
Journal of nanoscience and nanotechnology 2008;8(10):5494-8.
2008: Na-Youn Lee; Hye-Young Min; Jun Lee; Joo-Won Nam; Yoo-Jin Lee; Ah-Reum Han; Adam Wiryawan; Wahyu Suprapto; Sang Kook Lee; Eun-Kyoung Seo
Identification of a new cytotoxic biflavanone from Selaginella doederleinii.
Chemical & pharmaceutical bulletin 2008;56(9):1360-1.
2008: Ah-Reum Han; Hye-Young Min; Joo-Won Nam; Na-Youn Lee; Adam Wiryawan; Wahyu Suprapto; Sang Kook Lee; Kang Ro Lee; Eun-Kyoung Seo
Identification of a new naphthalene and its derivatives from the bulb of eleutherine americana with inhibitory activity on lipopolysaccharide-induced nitric oxide production.
Chemical & pharmaceutical bulletin 2008;56(9):1314-6.
2008: Jeong-Ho Hong; Eun Sun Yu; Ah-Reum Han; Joo-Won Nam; Eun-Kyoung Seo; Eun Sook Hwang
Isoeleutherin and eleutherinol, naturally occurring selective modulators of Th cell-mediated immune responses.
Biochemical and biophysical research communications 2008;371(2):278-82.
2008: Ah-Reum Han; Hye Jeoung Kim; Minkyu Shin; Moochang Hong; Yang Seok Kim; Hyunsu Bae
Constituents of Asarum sieboldii with inhibitory activity on lipopolysaccharide (LPS)-induced NO production in BV-2 microglial cells.
Chemistry & biodiversity 2008;5(2):346-51.
2008: Myoung Suk Choi; Eui Chul Kim; Hyung Suk Lee; Sun Kwang Kim; Hyun Myung Choi; Jung Hyuk Park; Jae-Bok Han; Hyo-Jin An; Jae-Young Um; Hyung Min Kim; Ah-Reum Han; Moo-Chang Hong; Hyunsu Bae; Byung-Il Min
Inhibitory effects of Saururus chinensis (LOUR.) BAILL on the development of atopic dermatitis-like skin lesions in NC/Nga mice.
Biological & pharmaceutical bulletin 2008;31(1):51-6.
2007: Jong Bin Kim; Ah-Reum Han; Eun-Young Park; Ji-Yeon Kim; Woong Cho; Jun Lee; Eun-Kyoung Seo; Kyung-Tae Lee
Inhibition of LPS-induced iNOS, COX-2 and cytokines expression by poncirin through the NF-kappaB inactivation in RAW 264.7 macrophage cells.
Biological & pharmaceutical bulletin 2007;30(12):2345-51.
2007: Won Seok Jung; Ah-Reum Han; Jay Sung Joong Hong; Sung Ryeol Park; Cha Yong Choi; Je Won Park; Yeo Joon Yoon
Bioconversion of 12-, 14-, and 16-membered ring aglycones to glycosylated macrolides in an engineered strain of Streptomyces venezuelae.
Applied microbiology and biotechnology 2007;76(6):1373-81.
2007: Ah-Reum Han; Jong Bin Kim; Jun Lee; Joo-Won Nam; Ik-Soo Lee; Chang-Koo Shim; Kyung-Tae Lee; Eun-Kyoung Seo
A new flavanone glycoside from the dried immature fruits of Poncirus trifoliata.
Chemical & pharmaceutical bulletin 2007;55(8):1270-3.
2007: Jong-Won Lee; Hye-Young Min; Ah-Reum Han; Hwa-Jin Chung; Eun-Jung Park; Hyen Joo Park; Ji-Young Hong; Eun-Kyoung Seo; Sang Kook Lee
Growth inhibition and induction of G1 phase cell cycle arrest in human lung cancer cells by a phenylbutenoid dimer isolated from Zingiber cassumunar.
Biological & pharmaceutical bulletin 2007;30(8):1561-4.
2007: Ah-Reum Han; Hyen Joo Park; Daofeng Chen; Dae Sik Jang; Hwa-Jung Kim; Sang Kook Lee; Eun-Kyoung Seo
Topoisomerase-II-inhibitory principles from the stems of Spatholobus suberectus.
Chemistry & biodiversity 2007;4(7):1487-91.
2007: Soo Yeon Chung; Dae Sik Jang; Ah-Reum Han; Jung Ok Jang; Youngjoo Kwon; Eun-Kyoung Seo; Hwa Jeong Lee
Modulation of P-glycoprotein-mediated resistance by kaempferol derivatives isolated from Zingiber zerumbet.
Phytotherapy research : PTR 2007;21(6):565-9.
2007: Yeon Hee Jeong; Soo Yeon Chung; Ah-Reum Han; Min Kyung Sung; Dae Sik Jang; Jun Lee; Youngjoo Kwon; Hwa Jeong Lee; Eun-Kyoung Seo
P-glycoprotein inhibitory activity of two phenolic compounds, (-)-syringaresinol and tricin from Sasa borealis.
Chemistry & biodiversity 2007;4(1):12-6.
2006: Won Seok Jung; Sang Kil Lee; Jay Sung Joong Hong; Sung Ryeol Park; Soon Jeong Jeong; Ah-Reum Han; Jae Kyung Sohng; Byung-Gee Kim; Cha Yong Choi; David H Sherman; Yeo Joon Yoon
Heterologous expression of tylosin polyketide synthase and production of a hybrid bioactive macrolide in Streptomyces venezuelae.
Applied microbiology and biotechnology 2006;72(4):763-9.
2006: Ah-Reum Han; You-Jin Kang; Tri Windono; Sang Kook Lee; Eun-Kyoung Seo
Prenylated flavonoids from the heartwood of Artocarpus communis with inhibitory activity on lipopolysaccharide-induced nitric oxide production.
Journal of natural products 2006;69(4):719-21.
2006: Bo-Eun Ahn; Joonseok Cha; Eun-Jin Lee; Ah-Reum Han; Charles J Thompson; Jung-Hye Roe
Nur, a nickel-responsive regulator of the Fur family, regulates superoxide dismutases and nickel transport in Streptomyces coelicolor.
Molecular microbiology 2006;59(6):1848-58.
2005: Ah-Reum Han; Moon-Sun Kim; Yeon Hee Jeong; Sang Kook Lee; Eun-Kyoung Seo
Cyclooxygenase-2 inhibitory phenylbutenoids from the rhizomes of Zingiber cassumunar.
Chemical & pharmaceutical bulletin 2005;53(11):1466-8.
2005: Dae Sik Jang; Hye-Young Min; Moon-Sun Kim; Ah-Reum Han; Tri Windono; Gwang-Ho Jeohn; Sam Sik Kang; Sang Kook Lee; Eun-Kyoung Seo
Humulene derivatives from Zingiber zerumbet with the inhibitory effects on lipopolysaccharide-induced nitric oxide production.
Chemical & pharmaceutical bulletin 2005;53(7):829-31.
2005: In-Kyung Bae; Hye-Young Min; Ah-Reum Han; Eun-Kyoung Seo; Sang Kook Lee
Suppression of lipopolysaccharide-induced expression of inducible nitric oxide synthase by brazilin in RAW 264.7 macrophage cells.
European journal of pharmacology 2005;513(3):237-42.
2005: Ah-Reum Han; Jun-Im Song; Dae Sik Jang; Hye-Young Min; Sang Kook Lee; Eun-Kyoung Seo
Cytotoxic constituents of the octocoral Dendronephthya gigantea.
Archives of pharmacal research 2005;28(3):290-3.
2004: Ah-Reum Han; Hye-Young Min; Tri Windono; Gwang-Ho Jeohn; Dae Sik Jang; Sang Kook Lee; Eun-Kyoung Seo
A new cytotoxic phenylbutenoid dimer from the rhizomes of Zingiber cassumunar.
Planta medica 2004;70(11):1095-7.
2004: Dae Sik Jang; Ah-Reum Han; Gowooni Park; Gil-Ja Jhon; Eun-Kyoung Seo
Flavonoids and aromatic compounds from the rhizomes of Zingiber zerumbet.
Archives of pharmacal research 2004;27(4):386-9.
2004: Kang-Hoon Je; Ah-Reum Han; Hyun-Tai Lee; Woongchon Mar; Eun-Kyoung Seo
The inhibitory principle of lipopolysaccharide-induced nitric oxide production from Inula britannica var. chinensis.
Archives of pharmacal research 2004;27(1):83-5.