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Min Han

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Publications

TOP 3
Rongbo Li; Tian Xu; Yuan Zhuang; Min Han; Xiaohui Wu
piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice.
Marina Kniazeva; Min Han
Fat chance for longevity.
Kai Lei; Chunlin Shao; Rener Xu; Tian Xu; Xiaoqiang Zhu; Yuan Zhuang; Min Han
Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response.

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All Publications

2013: Rongbo Li; Tian Xu; Yuan Zhuang; Min Han; Xiaohui Wu
piggyBac as a high-capacity transgenesis and gene-therapy vector in human cells and mice.
Disease models & mechanisms 2013;6(3):828-33.
2013: Marina Kniazeva; Min Han
Fat chance for longevity.
Genes & development 2013;27(4):351-4.
2012: Kai Lei; Chunlin Shao; Rener Xu; Tian Xu; Xiaoqiang Zhu; Yuan Zhuang; Min Han
Inner nuclear envelope proteins SUN1 and SUN2 play a prominent role in the DNA damage response.
Current biology : CB 2012;22(17):1609-15.
2012: Brian A Kudlow; Liang Zhang; Min Han
Systematic analysis of tissue-restricted miRISCs reveals a broad role for microRNAs in suppressing basal activity of the C. elegans pathogen response.
Molecular cell 2012;46(4):530-41.
2012: Marina Kniazeva; Huali Shen; Chen Wang; Tetyana Euler; Min Han
Regulation of maternal phospholipid composition and IP(3)-dependent embryonic membrane dynamics by a specific fatty acid metabolic event in C. elegans.
Genes & development 2012;26(6):554-66.
2011: Xiaochang Zhang; Mingxue Cui; Yudong Teng; Rebecca Zabinsky; Min Han
microRNAs play critical roles in the survival and recovery of Caenorhabditis elegans from starvation-induced L1 diapause.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(44):17997-8002.
2011: Zengli Guo; Hongmei Li; Min Han; Tian Xu; Xiaohui Wu; Yuan Zhuang
Modeling Sjögren's syndrome with Id3 conditional knockout mice.
Immunology letters 2011;135(1-2):34-42.
2010: Xiaochang Zhang; Min Han
Nuclear migration: rock and roll facilitated by dynein and kinesin.
Current biology : CB 2010;20(23):R1027-9.
2010: Chi Zhang; Lei Tian; Congwu Chi; Xiaohui Wu; Xiao Yang; Min Han; Tian Xu; Yuan Zhuang; Kejing Deng
Adam10 is essential for early embryonic cardiovascular development.
Developmental dynamics : an official publication of the American Association of Anatomists 2010;239(10):2594-602.
2010: Congwu Chi; Huanhu Zhu; Min Han; Yuan Zhuang; Xiaohui Wu; Tian Xu
Disruption of lysosome function promotes tumor growth and metastasis in Drosophila.
The Journal of biological chemistry 2010;285(28):21817-23.
2010: Jing Yi; Muyun Chen; Xiaohui Wu; Xiao Yang; Tian Xu; Yuan Zhuang; Min Han; Rener Xu
Endothelial SUR-8 acts in an ERK-independent pathway during atrioventricular cushion development.
Developmental dynamics : an official publication of the American Association of Anatomists 2010;239(7):2005-13.
2010: Min Han
Advancing biology with a growing worm field.
Developmental dynamics : an official publication of the American Association of Anatomists 2010;239(5):1263-4.
2009: Xiaochang Zhang; Kai Lei; Xiaobing Yuan; Xiaohui Wu; Yuan Zhuang; Tian Xu; Rener Xu; Min Han
SUN1/2 and Syne/Nesprin-1/2 complexes connect centrosome to the nucleus during neurogenesis and neuronal migration in mice.
Neuron 2009;64(2):173-87.
2009: Juehua Yu; Mingyao Ying; Yuan Zhuang; Tian Xu; Min Han; Xiaohui Wu; Rener Xu
C-terminal deletion of the atrophin-1 protein results in growth retardation but not neurodegeneration in mice.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(10):2471-8.
2009: Yongli Dong; Xingrong Du; Jian Ye; Min Han; Tian Xu; Yuan Zhuang; Wufan Tao
A cell-intrinsic role for Mst1 in regulating thymocyte egress.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(6):3865-72.
2009: Liang Zhang; Molly Hammell; Brian A Kudlow; Victor Ambros; Min Han
Systematic analysis of dynamic miRNA-target interactions during C. elegans development.
Development (Cambridge, England) 2009;136(18):3043-55.
2009: Emylie Seamen; Jennifer M Blanchette; Min Han
P-type ATPase TAT-2 negatively regulates monomethyl branched-chain fatty acid mediated function in post-embryonic growth and development in C. elegans.
PLoS genetics 2009;5(8):e1000589.
2009: Kai Lei; Xiaochang Zhang; Xu Ding; Xue Guo; Muyun Chen; Binggen Zhu; Tian Xu; Yuan Zhuang; Rener Xu; Min Han
SUN1 and SUN2 play critical but partially redundant roles in anchoring nuclei in skeletal muscle cells in mice.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(25):10207-12.
2009: Yue Wu; Yuan Zhuang; Min Han; Tian Xu; Kejing Deng
Ras promotes cell survival by antagonizing both JNK and Hid signals in the Drosophila eye.
BMC developmental biology 2009;9():53.
2008: Rong Xu; Kejing Deng; Yi Zhu; Yue Wu; Jing Ren; Min Wan; Shouyuan Zhao; Xiaohui Wu; Min Han; Yuan Zhuang; Tian Xu
A large-scale functional approach to uncover human genes and pathways in Drosophila.
Cell research 2008;18(11):1114-27.
2008: Mingxue Cui; Mary Ann Allen; Alison Larsen; Margaret MacMorris; Min Han; Thomas Blumenthal
Genes involved in pre-mRNA 3'-end formation and transcription termination revealed by a lin-15 operon Muv suppressor screen.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(43):16665-70.
2008: Lei Tian; Xiaohui Wu; Congwu Chi; Min Han; Tian Xu; Yuan Zhuang
ADAM10 is essential for proteolytic activation of Notch during thymocyte development.
International immunology 2008;20(9):1181-7.
2008: Marina Kniazeva; Tanya Euler; Min Han
A branched-chain fatty acid is involved in post-embryonic growth control in parallel to the insulin receptor pathway and its biosynthesis is feedback-regulated in C. elegans.
Genes & development 2008;22(15):2102-10.
2008: Morgan Tucker; Min Han
Muscle cell migrations of C. elegans are mediated by the alpha-integrin INA-1, Eph receptor VAB-1, and a novel peptidase homologue MNP-1.
Developmental biology 2008;318(2):215-23.
2008: Lei Sun; Xiaohui Wu; Min Han; Tian Xu; Yuan Zhuang
A mitotic recombination system for mouse chromosome 17.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(11):4237-41.
2008: Ling V Sun; Ke Jin; Yiming Liu; Wenwei Yang; Xing Xie; Lin Ye; Li Wang; Lin Zhu; Sheng Ding; Yi Su; Jie Zhou; Min Han; Yuan Zhuang; Tian Xu; Xiaohui Wu; Ning Gu; Yang Zhong
PBmice: an integrated database system of piggyBac (PB) insertional mutations and their characterizations in mice.
Nucleic acids research 2008;36(Database issue):D729-34.
2007: Liang Zhang; Lei Ding; Tom H Cheung; Meng-Qiu Dong; Jun Chen; Aileen K Sewell; Xuedong Liu; John R Yates; Min Han
Systematic identification of C. elegans miRISC proteins, miRNAs, and mRNA targets by their interactions with GW182 proteins AIN-1 and AIN-2.
Molecular cell 2007;28(4):598-613.
2007: Lei Ding; Min Han
GW182 family proteins are crucial for microRNA-mediated gene silencing.
Trends in cell biology 2007;17(8):411-6.
2007: Xu Ding; Rener Xu; Juehua Yu; Tian Xu; Yuan Zhuang; Min Han
SUN1 is required for telomere attachment to nuclear envelope and gametogenesis in mice.
Developmental cell 2007;12(6):863-72.
2007: Xiaochang Zhang; Rener Xu; Binggen Zhu; Xiujuan Yang; Xu Ding; Shumin Duan; Tian Xu; Yuan Zhuang; Min Han
Syne-1 and Syne-2 play crucial roles in myonuclear anchorage and motor neuron innervation.
Development (Cambridge, England) 2007;134(5):901-8.
2007: Mingxue Cui; Min Han
Roles of chromatin factors in C. elegans development.
WormBook : the online review of C. elegans biology 2007;():1-16.
2006: Kiyokazu Morita; Min Han
Multiple mechanisms are involved in regulating the expression of the developmental timing regulator lin-28 in Caenorhabditis elegans.
The EMBO journal 2006;25(24):5794-804.
2006: Min Wan; Xiaohui Wu; Kun-Liang Guan; Min Han; Yuan Zhuang; Tian Xu
Muscle atrophy in transgenic mice expressing a human TSC1 transgene.
FEBS letters 2006;580(24):5621-7.
2006: Min Han; Li-Mei Han; Qing-song Wang; Zhi-Hua Bai; Xiao-ling Fang
[Mechanism of oral absorption of panaxnotoginseng saponins].
Yao xue xue bao = Acta pharmaceutica Sinica 2006;41(6):498-505.
2006: Mingyao Ying; Rener Xu; Xiaohui Wu; Huaxing Zhu; Yuan Zhuang; Min Han; Tian Xu
Sodium butyrate ameliorates histone hypoacetylation and neurodegenerative phenotypes in a mouse model for DRPLA.
The Journal of biological chemistry 2006;281(18):12580-6.
2006: Mingxue Cui; E Bridget Kim; Min Han
Diverse chromatin remodeling genes antagonize the Rb-involved SynMuv pathways in C. elegans.
PLoS genetics 2006;2(5):e74.
2006: Mingxue Cui; Jun Chen; Toshia R Myers; Byung Joon Hwang; Paul W Sternberg; Iva Greenwald; Min Han
SynMuv genes redundantly inhibit lin-3/EGF expression to prevent inappropriate vulval induction in C. elegans.
Developmental cell 2006;10(5):667-72.
2006: Min Han; Xian-yi Sha; Yunjuan Wu; Xiaoling Fang
Oral absorption of ginsenoside Rb1 using in vitro and in vivo models.
Planta medica 2006;72(5):398-404.
2006: Min Han; Xiao-ling Fang
Difference in oral absorption of ginsenoside Rg1 between in vitro and in vivo models.
Acta pharmacologica Sinica 2006;27(4):499-505.
2006: Yo Suzuki; Min Han
Genetic redundancy masks diverse functions of the tumor suppressor gene PTEN during C. elegans development.
Genes & development 2006;20(4):423-8.
2006: Juehua Yu; Daniel A Starr; Xiaohui Wu; Susan M Parkhurst; Yuan Zhuang; Tian Xu; Rener Xu; Min Han
The KASH domain protein MSP-300 plays an essential role in nuclear anchoring during Drosophila oogenesis.
Developmental biology 2006;289(2):336-45.
2005: Dennis J Eastburn; Min Han
A gain-of-function allele of cbp-1, the Caenorhabditis elegans ortholog of the mammalian CBP/p300 gene, causes an increase in histone acetyltransferase activity and antagonism of activated Ras.
Molecular and cellular biology 2005;25(21):9427-34.
2005: Morgan Tucker; Matt Sieber; Mary Morphew; Min Han
The Caenorhabditis elegans aristaless orthologue, alr-1, is required for maintaining the functional and structural integrity of the amphid sensory organs.
Molecular biology of the cell 2005;16(10):4695-704.
2005: Lei Ding; Andrew Spencer; Kiyokazu Morita; Min Han
The developmental timing regulator AIN-1 interacts with miRISCs and may target the argonaute protein ALG-1 to cytoplasmic P bodies in C. elegans.
Molecular cell 2005;19(4):437-47.
2005: Sheng Ding; Xiaohui Wu; Gang Li; Min Han; Yuan Zhuang; Tian Xu
Efficient transposition of the piggyBac (PB) transposon in mammalian cells and mice.
Cell 2005;122(3):473-83.
2005: Huaxing Zhu; Guangxue Wang; Gang Li; Min Han; Tian Xu; Yuan Zhuang; Xiaohui Wu
Ubiquitous expression of mRFP1 in transgenic mice.
Genesis (New York, N.Y. : 2000) 2005;42(2):86-90.
2004: Marina Kniazeva; Quinn T Crawford; Matt Seiber; Cun-Yu Wang; Min Han
Monomethyl branched-chain fatty acids play an essential role in Caenorhabditis elegans development.
PLoS biology 2004;2(9):E257.
2004: Zhe Chen; Dennis J Eastburn; Min Han
The Caenorhabditis elegans nuclear receptor gene nhr-25 regulates epidermal cell development.
Molecular and cellular biology 2004;24(17):7345-58.
2004: Mingxue Cui; David Fay; Min Han
lin-35/Rb cooperates with the SWI/SNF complex to control Caenorhabditis elegans larval development.
Genetics 2004;167(3):1177-85.
2004: Dennis Eastburn; Min Han
When Ras signaling reaches the mediator.
Developmental cell 2004;6(2):158-9.
2004: John H Yoder; Huira C. Kopera; Kun-Liang Guan; Min Han
Modulation of KSR activity in Caenorhabditis elegans by Zn ions, PAR-1 kinase and PP2A phosphatase.
The EMBO journal 2004;23(1):111-9.
2003: Fang Wang; John Yoder; Igor Antoshechkin; Min Han
Caenorhabditis elegans EVL-14/PDS-5 and SCC-3 are essential for sister chromatid cohesion in meiosis and mitosis.
Molecular and cellular biology 2003;23(21):7698-707.
2003: Daniel A Starr; Min Han
ANChors away: an actin based mechanism of nuclear positioning.
Journal of cell science 2003;116(Pt 2):211-6.
2003: Marina Kniazeva; Matt Sieber; Scott McCauley; Kang Zhang; Jennifer L Watts; Min Han
Suppression of the ELO-2 FA elongation activity results in alterations of the fatty acid composition and multiple physiological defects, including abnormal ultradian rhythms, in Caenorhabditis elegans.
Genetics 2003;163(1):159-69.
2002: Yo Suzuki; Gail A Morris; Min Han; William B Wood
A cuticle collagen encoded by the lon-3 gene may be a target of TGF-beta signaling in determining Caenorhabditis elegans body shape.
Genetics 2002;162(4):1631-9.
2002: Daniel A Starr; Min Han
Role of ANC-1 in tethering nuclei to the actin cytoskeleton.
Science (New York, N.Y.) 2002;298(5592):406-9.
2002: Igor Antoshechkin; Min Han
The C. elegans evl-20 gene is a homolog of the small GTPase ARL2 and regulates cytoskeleton dynamics during cytokinesis and morphogenesis.
Developmental cell 2002;2(5):579-91.
2002: Kenneth K Lee; Daniel A Starr; Merav Cohen; Jun Liu; Min Han; Katherine L Wilson; Yosef Gruenbaum
Lamin-dependent localization of UNC-84, a protein required for nuclear migration in Caenorhabditis elegans.
Molecular biology of the cell 2002;13(3):892-901.
2002: David Fay; Sean Keenan; Min Han
fzr-1 and lin-35/Rb function redundantly to control cell proliferation in C. elegans as revealed by a nonbiased synthetic screen.
Genes & development 2002;16(4):503-17.
2002: Wendy Hanna-Rose; Min Han
The Caenorhabditis elegans EGL-26 protein mediates vulval cell morphogenesis.
Developmental biology 2002;241(2):247-58.
2001: Daniel A Starr; Greg J Hermann; Christian Malone; W Fixsen; James R Priess; H Robert Horvitz; Min Han
unc-83 encodes a novel component of the nuclear envelope and is essential for proper nuclear migration.
Development (Cambridge, England) 2001;128(24):5039-50.
2001: Zhe Chen; Min Han
Role of C. elegans lin-40 MTA in vulval fate specification and morphogenesis.
Development (Cambridge, England) 2001;128(23):4911-21.
2001: Zhe Chen; Min Han
C. elegans Rb, NuRD, and Ras regulate lin-39-mediated cell fusion during vulval fate specification.
Current biology : CB 2001;11(23):1874-9.
2001: J H Yoder; Min Han
Cytoplasmic dynein light intermediate chain is required for discrete aspects of mitosis in Caenorhabditis elegans.
Molecular biology of the cell 2001;12(10):2921-33.
2001: Kang Zhang; MF Kniazeva; Min Han; W Li; Z Yu; Zhenglin Yang; Yingying Li; Michael Metzker; Rando Allikmets; Donald J Zack; Laura E Kakuk; Pamela S Lagali; Paul W Wong; Ian M MacDonald; Paul Sieving; David Figueroa; Christopher P Austin; Robert Gould; Radha Ayyagari; Konstantin Petrukhin
A 5-bp deletion in ELOVL4 is associated with two related forms of autosomal dominant macular dystrophy.
Nature genetics 2001;27(1):89-93.
2000: W Hanna-Rose; Min Han
Getting signals crossed in C. elegans.
Current opinion in genetics & development 2000;10(5):523-8.
2000: David Fay; Min Han
Mutations in cye-1, a Caenorhabditis elegans cyclin E homolog, reveal coordination between cell-cycle control and vulval development.
Development (Cambridge, England) 2000;127(18):4049-60.
2000: Marina Kniazeva; Elias Traboulsi; Z Yu; Susan Tonya Stefko; Michael B Gorin; Yin Yao Shugart; Jeffrey R O'Connell; C J Blaschak; Garry R Cutting; Min Han; Kang Zhang
A new locus for dominant drusen and macular degeneration maps to chromosome 6q14.
American journal of ophthalmology 2000;130(2):197-202.
2000: Zhe Chen; Min Han
Building a protein interaction map: research in the post-genome era.
BioEssays : news and reviews in molecular, cellular and developmental biology 2000;22(6):503-6.
2000: David Fay; Min Han
The synthetic multivulval genes of C. elegans: functional redundancy, Ras-antagonism, and cell fate determination.
Genesis (New York, N.Y. : 2000) 2000;26(4):279-84.
1999: Kang Zhang; Daniel C Garibaldi; MF Kniazeva; Thomas Albini; Michael Chiang; M Kerrigan; Janet S Sunness; Min Han; Rando Allikmets
A novel mutation in the ABCR gene in four patients with autosomal recessive Stargardt disease.
American journal of ophthalmology 1999;128(6):720-4.
1999: D S Sieburth; M Sundaram; R M Howard; Min Han
A PP2A regulatory subunit positively regulates Ras-mediated signaling during Caenorhabditis elegans vulval induction.
Genes & development 1999;13(19):2562-9.
1999: Kang Zhang; MF Kniazeva; A Hutchinson; Min Han; M Dean; Rando Allikmets
The ABCR gene in recessive and dominant Stargardt diseases: a genetic pathway in macular degeneration.
Genomics 1999;60(2):234-7.
1999: MF Kniazeva; Michael Chiang; Garry R Cutting; Donald J Zack; Min Han; Kang Zhang
Clinical and genetic studies of an autosomal dominant cone-rod dystrophy with features of Stargardt disease.
Ophthalmic genetics 1999;20(2):71-81.
1999: Christian Malone; W D Fixsen; H Robert Horvitz; Min Han
UNC-84 localizes to the nuclear envelope and is required for nuclear migration and anchoring during C. elegans development.
Development (Cambridge, England) 1999;126(14):3171-81.
1999: MF Kniazeva; Michael Chiang; B Morgan; A L Anduze; Donald J Zack; Min Han; Kang Zhang
A new locus for autosomal dominant stargardt-like disease maps to chromosome 4.
American journal of human genetics 1999;64(5):1394-9.
1999: J Yochem; Simon Tuck; I Greenwald; Min Han
A gp330/megalin-related protein is required in the major epidermis of Caenorhabditis elegans for completion of molting.
Development (Cambridge, England) 1999;126(3):597-606.
1999: David Fay; H M Stanley; Min Han; William B Wood
A Caenorhabditis elegans homologue of hunchback is required for late stages of development but not early embryonic patterning.
Developmental biology 1999;205(2):240-53.
1999: W Hanna-Rose; Min Han
COG-2, a sox domain protein necessary for establishing a functional vulval-uterine connection in Caenorhabditis elegans.
Development (Cambridge, England) 1999;126(1):169-79.
1998: T Gu; S Orita; Min Han
Caenorhabditis elegans SUR-5, a novel but conserved protein, negatively regulates LET-60 Ras activity during vulval induction.
Molecular and cellular biology 1998;18(8):4556-64.
1998: D S Sieburth; Q Sun; Min Han
SUR-8, a conserved Ras-binding protein with leucine-rich repeats, positively regulates Ras-mediated signaling in C. elegans.
Cell 1998;94(1):119-30.
1998: J Yochem; T Gu; Min Han
A new marker for mosaic analysis in Caenorhabditis elegans indicates a fusion between hyp6 and hyp7, two major components of the hypodermis.
Genetics 1998;149(3):1323-34.
1998: J A Dent; Min Han
Post-embryonic expression pattern of C. elegans let-60 ras reporter constructs.
Mechanisms of development 1998;72(1-2):179-82.
1997: Min Han
Gut reaction to Wnt signaling in worms.
Cell 1997;90(4):581-4.
1997: J Yochem; M Sundaram; Min Han
Ras is required for a limited number of cell fates and not for general proliferation in Caenorhabditis elegans.
Molecular and cellular biology 1997;17(5):2716-22.
1996: M Sundaram; J Yochem; Min Han
A Ras-mediated signal transduction pathway is involved in the control of sex myoblast migration in Caenorhabditis elegans.
Development (Cambridge, England) 1996;122(9):2823-33.
1996: M Sundaram; Min Han
Control and integration of cell signaling pathways during C. elegans vulval development.
BioEssays : news and reviews in molecular, cellular and developmental biology 1996;18(6):473-80.
1995: N Singh; Min Han
sur-2, a novel gene, functions late in the let-60 ras-mediated signaling pathway during Caenorhabditis elegans vulval induction.
Genes & development 1995;9(18):2251-65.
1995: M Hara; Min Han
Ras farnesyltransferase inhibitors suppress the phenotype resulting from an activated ras mutation in Caenorhabditis elegans.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(8):3333-7.
1995: Y Wu; Min Han; K L Guan
MEK-2, a Caenorhabditis elegans MAP kinase kinase, functions in Ras-mediated vulval induction and other developmental events.
Genes & development 1995;9(6):742-55.
1994: Y Wu; Min Han
Suppression of activated Let-60 ras protein defines a role of Caenorhabditis elegans Sur-1 MAP kinase in vulval differentiation.
Genes & development 1994;8(2):147-59.
1993: Min Han; A Golden; Y Han; P W Sternberg
C. elegans lin-45 raf gene participates in let-60 ras-stimulated vulval differentiation.
Nature 1993;363(6425):133-40.
1992: Min Han
Ras proteins in developmental pattern formation in Caenorhabditis elegans and Drosophila.
Seminars in cancer biology 1992;3(4):219-28.