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Yi-Fan Han
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Research Profile (preview)
Chemicals & Drugs
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Physiology
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Network (preview)
16
Pang, Yuan-Ping
12
Carlier, Paul
8
Pan, Si-Yuan
6
Lee, Nelson
5
Li, Zhi-Wang
5
Wang, Hui
5
Ko, Kam Ming
4
Dong, Hang
3
Li, CP
3
Kan, Kelvin
3
Wu, DC
3
Xiao, Xiao Qiu
3
Li, Wen-Ming
3
Yu, Hua
2
Yu, Zhi-ling
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Publications
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Geonetwork of Yi-Fan Han (preview)
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All Publications
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2010: Choi Roy C Y; Zhu Judy T T; Leung K Wing; Chu Glanice K Y; Xie Heidi Q; Chen Vicky P; Zheng Ken Y Z; Lau David T W; Dong Tina T X; Chow Peter C Y; Han Yi-Fan; Wang Zheng-Tao; Tsim Karl W K
A flavonol glycoside, isolated from roots of Panax notoginseng, reduces amyloid-beta-induced neurotoxicity in cultured neurons: signaling transduction and drug development for Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2010;19(3):795-811.
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2009: Zhou Li; Liu Yu-Wei; Peoples Robert W; Yang Min; Tian Xiang; Ai Yong-Xun; Pang Yuan-Ping; Li Zhi-Wang; Han Yi-Fan; Li Chao-Ying
Mechanism of bis(7)-tacrine inhibition of GABA-activated current in cultured rat hippocampal neurons.
Neuropharmacology 2009;57(1):33-40.
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2009: Yu Hua; Li Wen Ming; Cheung Man Chun; Zuo Zhong; Carlier Paul R; Gu Ze Ming; Chan Kelvin; Huang Min; Wang Yi Tao; Han Yi Fan
Development and validation of an HPLC-DAD method for bis(12)-hupyridone and its application to a pharmacokinetic study.
Journal of pharmaceutical and biomedical analysis 2009;49(2):410-4.
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2008: Liu Yu-Wei; Luo Jia-Lie; Ren Hong; Peoples Robert W; Ai Yong-Xun; Liu Li-Jiang; Pang Yuan-Ping; Li Zhi-Wang; Han Yi-Fan; Li Chao-Ying
Inhibition of NMDA-gated ion channels by bis(7)-tacrine: whole-cell and single-channel studies.
Neuropharmacology 2008;54(7):1086-94.
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2008: Zhang Li; Yu Hua; Li Wen Ming; Cheung Man Chun; Pang Yuan Ping; Gu Ze Ming; Chan Kelvin; Wang Yi Tao; Zuo Zhong; Han Yi Fan
Preclinical characterization of intestinal absorption and metabolism of promising anti-Alzheimer's dimer bis(7)-tacrine.
International journal of pharmaceutics 2008;357(1-2):85-94.
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2008: Yu Hua; Li Wen-Ming; Kan Kelvin K W; Ho Jason M K; Carlier Paul R; Pang Yuan-Ping; Gu Zhe-Ming; Zhong Zuo; Chan Kelvin; Wang Yi-Tao; Han Yi-Fan
The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine.
Journal of pharmaceutical and biomedical analysis 2008;46(1):75-81.
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2007: Ng Ka-Lun; Lam Chui-Chi; Fu Zhibiao; Han Yi-Fan; Tsim Karl W K; Wong Wan-Keung R
Cloning and characterization of the yjeA gene, encoding a novel deoxyribonuclease, from Bacillus subtilis.
Journal of biochemistry 2007;142(5):647-54.
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2007: Li W M; Kan K K W; Carlier P R; Pang Y P; Han Y F
East meets West in the search for Alzheimer's therapeutics - novel dimeric inhibitors from tacrine and huperzine A.
Current Alzheimer research 2007;4(4):386-96.
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2007: Yu Hua; Ho Jason M K; Kan Kelvin K W; Cheng Bobby W H; Li Wen-Ming; Zhang Li; Lin Ge; Pang Yuan-Ping; Gu Zhe-Ming; Chan Kelvin; Wang Yi-Tao; Han Yi-Fan
Development of a high performance liquid chromatography-tandem mass method for determination of bis(7)-tacrine, a promising anti-Alzheimer's dimer, in rat blood.
Journal of pharmaceutical and biomedical analysis 2007;44(5):1133-8.
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2007: Pan S Y; Yu Z L; Dong H; Lee N T K; Wang H; Fong W F; Han Y F; Ko K M
Evaluation of acute bis(7)-tacrine treatment on behavioral functions in 17-day-old and 30-day-old mice, with attention to drug toxicity.
Pharmacology, biochemistry, and behavior 2007;86(4):778-83.
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2007: Nie Hui; Yu Wen-Jing; Li Xiang-Yuan; Yuan Chun-Hua; Pang Yuan-Ping; Li Chao-Ying; Han Yi-Fan; Li Zhi-Wang
Inhibition by bis(7)-tacrine of native delayed rectifier and KV1.2 encoded potassium channels.
Neuroscience letters 2007;412(2):108-13.
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2006: Pan S Y; Han Y F; Yu Z L; Yang R; Dong H; Ko K M
Evaluation of acute tacrine treatment on passive-avoidance response, open-field behavior, and toxicity in 17- and 30-day-old mice.
Pharmacology, biochemistry, and behavior 2006;85(1):50-6.
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2006: Pan Si-Yuan; Yang Rong; Han Yi-Fan; Dong Hang; Feng Xu-Dong; Li Na; Geng Wei; Ko Kam-Ming
High doses of bifendate elevate serum and hepatic triglyceride levels in rabbits and mice: animal models of acute hypertriglyceridemia.
Acta pharmacologica Sinica 2006;27(6):673-8.
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2006: Pan Si-Yuan; Dong Hang; Han Yi-Fan; Li Wen-Yuan; Zhao Xing-Ye; Ko Kam-Ming
A novel experimental model of acute hypertriglyceridemia induced by schisandrin B.
European journal of pharmacology 2006;537(1-3):200-4.
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2004: Pan S Y; Han Y F
Comparison of the inhibitory efficacy of four belladonna drugs on gastrointestinal movement and cognitive function in food-deprived mice.
Pharmacology 2004;72(3):177-83.
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2004: Luo Jia-Lie; Zhang Jian; Guan Bing-Cai; Pang Yuan-Ping; Han Yi-Fan; Li Zhi-Wang
Inhibition by bis(7)-tacrine of 5-HT-activated current in rat TG neurons.
Neuroreport 2004;15(8):1335-8.
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2003: Wong Dawn M; Greenblatt Harry M; Dvir Hay; Carlier Paul R; Han Yi-Fan; Pang Yuan-Ping; Silman Israel; Sussman Joel L
Acetylcholinesterase complexed with bivalent ligands related to huperzine a: experimental evidence for species-dependent protein-ligand complementarity.
Journal of the American Chemical Society 2003;125(2):363-73.
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2002: Pan S Y; Han Y F; Carlier P R; Pang Y P; Mak D H F; Lam B Y H; Ko K M
Schisandrin B protects against tacrine- and bis(7)-tacrine-induced hepatotoxicity and enhances cognitive function in mice.
Planta medica 2002;68(3):217-20.
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2000: Xiao X Q; Lee N T; Carlier P R; Pang Y; Han Y F
Bis(7)-tacrine, a promising anti-Alzheimer's agent, reduces hydrogen peroxide-induced injury in rat pheochromocytoma cells: comparison with tacrine.
Neuroscience letters 2000;290(3):197-200.
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2000: Wu D C; Yu Y P; Lee N T; Yu A C; Wang J H; Han Y F
The expression of Cdk5, p35, p39, and Cdk5 kinase activity in developing, adult, and aged rat brains.
Neurochemical research 2000;25(7):923-9.
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2000: Wu D C; Xiao X Q; Ng A K; Chen P M; Chung W; Lee N T; Carlier P R; Pang Y P; Yu A C; Han Y F;
Protection against ischemic injury in primary cultured mouse astrocytes by bis(7)-tacrine, a novel acetylcholinesterase inhibitor [corrected].
Neuroscience letters 2000;288(2):95-8.
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2000: Wang L M; Han Y F; Tang X C
Huperzine A improves cognitive deficits caused by chronic cerebral hypoperfusion in rats.
European journal of pharmacology 2000;398(1):65-72.
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2000: Xiao X Q; Wang R; Han Y F; Tang X C
Protective effects of huperzine A on beta-amyloid(25-35) induced oxidative injury in rat pheochromocytoma cells.
Neuroscience letters 2000;286(3):155-8.
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2000: Pan S Y; Han Y F
Learning deficits induced by 4 belladonna alkaloids are preferentially attenuated by tacrine.
Acta pharmacologica Sinica 2000;21(2):124-30.
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1999: Han Y F; Li C P; Chow E; Wang H; Pang Y P; Carlier P R
Dual-site binding of bivalent 4-aminopyridine- and 4-aminoquinoline-based AChE inhibitors: contribution of the hydrophobic alkylene tether to monomer and dimer affinities.
Bioorganic & medicinal chemistry 1999;7(11):2569-75.
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1999: Wang H; Carlier P R; Ho W L; Lee N T; Pang Y P; Han Y F
Attenuation of scopolamine-induced deficits in navigational memory performance in rats by bis(7)-tacrine, a novel dimeric AChE inhibitor.
Zhongguo yao li xue bao = Acta pharmacologica Sinica 1999;20(3):211-7.
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1999: Li C Y; Wang H; Xue H; Carlier P R; Hui K M; Pang Y P; Li Z W; Han Y F
Bis(7)-tacrine, a novel dimeric AChE inhibitor, is a potent GABA(A) receptor antagonist.
Neuroreport 1999;10(4):795-800.
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1999: Wang H; Carlier P R; Ho W L; Wu D C; Lee N T; Li C P; Pang Y P; Han Y F
Effects of bis(7)-tacrine, a novel anti-Alzheimer's agent, on rat brain AChE.
Neuroreport 1999;10(4):789-93.
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1999: Carlier P R; Han Y F; Chow E S; Li C P; Wang H; Lieu T X; Wong H S; Pang Y P
Evaluation of short-tether bis-THA AChE inhibitors. A further test of the dual binding site hypothesis.
Bioorganic & medicinal chemistry 1999;7(2):351-7.
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1998: Pan S Y; Han Y F; Xu Q P; Liu M Y; Ma H Z; Ding W J; Zhu R L
Belladonna alkaloids-induced behavioral changes and amnesia on open-field and step-through in 18-, 28-, and 38-day-old mice.
Zhongguo yao li xue bao = Acta pharmacologica Sinica 1998;19(2):112-6.
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