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Steven Artandi

Research Profile

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Publications

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Franklin L Zhong; Luis F Z Batista; Adam Freund; Matthew F Pech; Andrew S Venteicher; Steven E Artandi
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends.
Ci Chu; Kun Qu; Franklin L Zhong; Steven E Artandi; Howard Y Chang
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions.
Vittorio Sebastiano; Marius Wernig; Dana T Yeo; Cyd Khayter; Morgan L Maeder; Cherie L Ramirez; James F Angstman; Steven E Artandi; Luis F Z Batista; Mathew J Goodwin; Bahareh Haddad; John S Hawkins; J Keith Joung
In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases.

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All Publications

2012: Franklin L Zhong; Luis F Z Batista; Adam Freund; Matthew F Pech; Andrew S Venteicher; Steven E Artandi
TPP1 OB-fold domain controls telomere maintenance by recruiting telomerase to chromosome ends.
Cell 2012;150(3):481-94.
2011: Ci Chu; Kun Qu; Franklin L Zhong; Steven E Artandi; Howard Y Chang
Genomic maps of long noncoding RNA occupancy reveal principles of RNA-chromatin interactions.
Molecular cell 2011;44(4):667-78.
2011: Vittorio Sebastiano; Marius Wernig; Dana T Yeo; Cyd Khayter; Morgan L Maeder; Cherie L Ramirez; James F Angstman; Steven E Artandi; Luis F Z Batista; Mathew J Goodwin; Bahareh Haddad; John S Hawkins; J Keith Joung
In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases.
Stem cells (Dayton, Ohio) 2011;29(11):1717-26.
2011: Luis F Z Batista; Thomas R Cech; Athena M Cherry; Jinkuk Choi; Sharon M Crary; Neelam Giri; Ha Nam Nguyen; Matthew F Pech; Renee A Reijo Pera; Sharon A Savage; Vittorio Sebastiano; Marius Wernig; Kathleen T Xie; Arthur J Zaug; Franklin L Zhong; BLANCHE ALTER; Steven E Artandi
Telomere shortening and loss of self-renewal in dyskeratosis congenita induced pluripotent stem cells.
Nature 2011;474(7351):399-402.
2011: Matthew F Pech; Steven E Artandi
TRAPping telomerase within the intestinal stem cell niche.
The EMBO journal 2011;30(6):986-7.
2011: Franklin Zhong; Sharon A Savage; Marina Shkreli; Neelam Giri; Lea Jessop; Timothy Myers; Renee Chen; BLANCHE ALTER; Steven E Artandi
Disruption of telomerase trafficking by TCAB1 mutation causes dyskeratosis congenita.
Genes & development 2011;25(1):11-6.
2010: Alessandra Sacco; Foteini Mourkioti; Rose Tran; Jinkuk Choi; Michael Llewellyn; Peggy Kraft; Marina Shkreli; Scott Delp; Jason H Pomerantz; Steven E Artandi; Helen M Blau
Short telomeres and stem cell exhaustion model Duchenne muscular dystrophy in mdx/mTR mice.
Cell 2010;143(7):1059-71.
2010: Ji Yeon Hong; Jae-Il Park; Kyucheol Cho; Dongmin Gu; Hong Ji; Steven E Artandi; Pierre D McCrea
Shared molecular mechanisms regulate multiple catenin proteins: canonical Wnt signals and components modulate p120-catenin isoform-1 and additional p120 subfamily members.
Journal of cell science 2010;123(Pt 24):4351-65.
2010: Steven E Artandi; Ronald A DePinho
Telomeres and telomerase in cancer.
Carcinogenesis 2010;31(1):9-18.
2009: Steven E Artandi; Julia Promisel Cooper
Reverse transcribing the code for chromosome stability.
Molecular cell 2009;36(5):715-9.
2009: jae-il park; Andrew S Venteicher; Ji Yeon Hong; Jinkuk Choi; Sohee Jun; Marina Shkreli; Woody Chang; Zhaojing Meng; Peggie Cheung; Hong Ji; Margaret McLaughlin; Timothy D Veenstra; Roel Nusse; Pierre D McCrea; Steven E Artandi
Telomerase modulates Wnt signalling by association with target gene chromatin.
Nature 2009;460(7251):66-72.
2009: Luis F Z Batista; Steven E Artandi
Telomere uncapping, chromosomes, and carcinomas.
Cancer cell 2009;15(6):455-7.
2009: Andrew S Venteicher; Steven E Artandi
TCAB1: driving telomerase to Cajal bodies.
Cell cycle (Georgetown, Tex.) 2009;8(9):1329-31.
2009: Andrew S Venteicher; Eladio B Abreu; Zhaojing Meng; Kelly E McCann; Rebecca M Terns; Timothy D Veenstra; Michael P Terns; Steven E Artandi
A human telomerase holoenzyme protein required for Cajal body localization and telomere synthesis.
Science (New York, N.Y.) 2009;323(5914):644-8.
2008: Qing Gao; Gloria E Reynolds; Andrew Wilcox; Douglas Miller; Peggie Cheung; Steven E Artandi; John P Murnane
Telomerase-dependent and -independent chromosome healing in mouse embryonic stem cells.
DNA repair 2008;7(8):1233-49.
2008: Andrew S Venteicher; Zhaojing Meng; Philip Mason; Timothy D Veenstra; Steven E Artandi
Identification of ATPases pontin and reptin as telomerase components essential for holoenzyme assembly.
Cell 2008;132(6):945-57.
2008: Jinkuk Choi; Lucinda K Southworth; Kavita Y Sarin; Andrew S Venteicher; Wenxiu Ma; Woody Chang; Peggie Cheung; Sohee Jun; Maja K Artandi; Naman Shah; Stuart K Kim; Steven E Artandi
TERT promotes epithelial proliferation through transcriptional control of a Myc- and Wnt-related developmental program.
PLoS genetics 2008;4(1):e10.
2007: Sripriya Rajaraman; Jinkuk Choi; Peggie Cheung; Veronica Beaudry; Helen Moore; Steven E Artandi
Telomere uncapping in progenitor cells with critical telomere shortening is coupled to S-phase progression in vivo.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(45):17747-52.
2007: richard s maser; Kwok-Kin Wong; Erguen Sahin; Huili Xia; Maria Naylor; H Mason Hedberg; Steven E Artandi; Ronald A DePinho
DNA-dependent protein kinase catalytic subunit is not required for dysfunctional telomere fusion and checkpoint response in the telomerase-deficient mouse.
Molecular and cellular biology 2007;27(6):2253-65.
2007: Kavita Y Sarin; Steven E Artandi
Aging, graying and loss of melanocyte stem cells.
Stem cell reviews 2007;3(3):212-7.
2006: Steven E Artandi
Telomeres, telomerase, and human disease.
The New England journal of medicine 2006;355(12):1195-7.
2006: Steven E Artandi
Telomerase flies the coop: the telomerase RNA component as a viral-encoded oncogene.
The Journal of experimental medicine 2006;203(5):1143-5.
2006: Elaine J Middleman; Jinkuk Choi; Andrew S Venteicher; Peggie Cheung; Steven E Artandi
Regulation of cellular immortalization and steady-state levels of the telomerase reverse transcriptase through its carboxy-terminal domain.
Molecular and cellular biology 2006;26(6):2146-59.
2005: Kavita Y Sarin; Peggie Cheung; Daniel Gilison; Eunice Lee; Ruth I Tennen; Estee Wang; Maja K Artandi; Anthony E Oro; Steven E Artandi
Conditional telomerase induction causes proliferation of hair follicle stem cells.
Nature 2005;436(7053):1048-52.
2005: Steven E Artandi; Laura D Attardi
Pathways connecting telomeres and p53 in senescence, apoptosis, and cancer.
Biochemical and biophysical research communications 2005;331(3):881-90.
2003: Steven E Artandi
Complex roles for telomeres and telomerase in breast carcinogenesis.
Breast cancer research : BCR 2003;5(1):37-41.
2002: Rónán C O'Hagan; Sandy Chang; richard s maser; Ramya Mohan; Steven E Artandi; Lynda Chin; Ronald A DePinho
Telomere dysfunction provokes regional amplification and deletion in cancer genomes.
Cancer cell 2002;2(2):149-55.
2002: Steven E Artandi; Scott Alson; Maja K Tietze; Norman E Sharpless; Siqin Ye; Roger A. Greenberg; Diego H Castrillon; James W Horner; Sarah R Weiler; Ruben D Carrasco; Ronald A DePinho
Constitutive telomerase expression promotes mammary carcinomas in aging mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(12):8191-6.
2002: Steven E Artandi
Telomere shortening and cell fates in mouse models of neoplasia.
Trends in molecular medicine 2002;8(1):44-7.
2000: Kwok-Kin Wong; S Chang; Sarah R Weiler; S Ganesan; Jayanta Chaudhuri; C Zhu; Steven E Artandi; K Lenhard Rudolph; GJ Gottlieb; Lynda Chin; Frederick W Alt; Ronald A DePinho
Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation.
Nature genetics 2000;26(1):85-8.
2000: Steven E Artandi; S Chang; S L Lee; Scott Alson; GJ Gottlieb; Lynda Chin; Ronald A DePinho
Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice.
Nature 2000;406(6796):641-5.
2000: Steven E Artandi; Ronald A DePinho
Mice without telomerase: what can they teach us about human cancer?
Nature medicine 2000;6(8):852-5.
2000: Steven E Artandi; Ronald A DePinho
A critical role for telomeres in suppressing and facilitating carcinogenesis.
Current opinion in genetics & development 2000;10(1):39-46.
1999: Lynda Chin; Steven E Artandi; Q Shen; A Tam; S L Lee; GJ Gottlieb; Carol W Greider; Ronald A DePinho
p53 deficiency rescues the adverse effects of telomere loss and cooperates with telomere dysfunction to accelerate carcinogenesis.
Cell 1999;97(4):527-38.