FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Douglas Hanahan

Research Profile

Living Beings

Disorders

Anatomy

Islets of Langerhans

Chemicals & Drugs

Co-author Network

Publications

TOP 3
Anguraj Sadanandam; Bertram Wiedenmann; Stephan Wullschleger; Lewis C Cantley; Eric A Collisson; Maguy Del Rio; William J Gibb; Joe W Gray; Carsten Grotzinger; Krisztian Homicsko; William A Lannon; Benoit Lhermitte; Costas A Lyssiotis; Adam B Olshen; Liliane C Gonzalez Ostos; Douglas Hanahan
A colorectal cancer classification system that associates cellular phenotype and responses to therapy.
Ksenya Shchors; Lamorna Brown Swigart; Tarik Tihan; William A Weiss; Douglas Hanahan; Nan Li; Natalya Lyubynska; Anders I Persson; Fanya Rostker; Mitchel S Berger; Gerard I Evan
Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy.
Leanne Li; Douglas Hanahan
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Douglas Hanahan (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Anguraj Sadanandam; Bertram Wiedenmann; Stephan Wullschleger; Lewis C Cantley; Eric A Collisson; Maguy Del Rio; William J Gibb; Joe W Gray; Carsten Grotzinger; Krisztian Homicsko; William A Lannon; Benoit Lhermitte; Costas A Lyssiotis; Adam B Olshen; Liliane C Gonzalez Ostos; Douglas Hanahan
A colorectal cancer classification system that associates cellular phenotype and responses to therapy.
Nature medicine 2013;19(5):619-25.
2013: Ksenya Shchors; Lamorna Brown Swigart; Tarik Tihan; William A Weiss; Douglas Hanahan; Nan Li; Natalya Lyubynska; Anders I Persson; Fanya Rostker; Mitchel S Berger; Gerard I Evan
Using a preclinical mouse model of high-grade astrocytoma to optimize p53 restoration therapy.
Proceedings of the National Academy of Sciences of the United States of America 2013;110(16):E1480-9.
2013: Leanne Li; Douglas Hanahan
Hijacking the neuronal NMDAR signaling circuit to promote tumor growth and invasion.
Cell 2013;153(1):86-100.
2012: Michele De Palma; Douglas Hanahan
The biology of personalized cancer medicine: facing individual complexities underlying hallmark capabilities.
Molecular oncology 2012;6(2):111-27.
2012: Douglas Hanahan; Lisa M Coussens
Accessories to the crime: functions of cells recruited to the tumor microenvironment.
Cancer cell 2012;21(3):309-22.
2011: Peter Olson; Samuel R Perry; Gerald Chu; Olivier Nolan-Stevaux; Douglas Hanahan
Imaging guided trials of the angiogenesis inhibitor sunitinib in mouse models predict efficacy in pancreatic neuroendocrine but not ductal carcinoma.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(49):E1275-84.
2011: Helene Pere; Françoise Quintin-Colonna; Patrice Ravel; Federico Sandoval; Corinne Tanchot; Olivier Adotevi; Cécile Badoual; Frederic Batteux; Jagadeesh Bayry; Christopher Chiu; Estelle Dransart; Luis Carlos Ferreira; Wolf Herman Fridman; Sylvie Garcia; Alain Gey; Douglas Hanahan; Ludger Johannes; Yu-Chun Lone; Elie Marcheteau; Nathalie Merillon; Yves Montier; Brad H Nelson; Eric Tartour
A CCR4 antagonist combined with vaccines induces antigen-specific CD8+ T cells and tumor immunity against self antigens.
Blood 2011;118(18):4853-62.
2011: Marcela Franco; Douglas Hanahan; Eliane Cortez; Pernilla Roswall; Kristian Pietras
Pericytes promote endothelial cell survival through induction of autocrine VEGF-A signaling and Bcl-w expression.
Blood 2011;118(10):2906-17.
2011: Elizabeth Allen; Ian B Walters; Douglas Hanahan
Brivanib, a dual FGF/VEGF inhibitor, is active both first and second line against mouse pancreatic neuroendocrine tumors developing adaptive/evasive resistance to VEGF inhibition.
Clinical cancer research : an official journal of the American Association for Cancer Research 2011;17(16):5299-310.
2011: Liang Xie; Michael B Duncan; Douglas Hanahan; Richard O Hynes; Masahiro Inoue; Jack Lawler; Julie Lively; Margot Martino; Thomas M Mundel; Jessica Pahler; Kristofer Rubin; Mary A Soubasakos; Hikaru Sugimoto; Takaaki Takeda; Raghu Kalluri
Counterbalancing angiogenic regulatory factors control the rate of cancer progression and survival in a stage-specific manner.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(24):9939-44.
2011: Beverly L Falcon; Kristian Pietras; Jeyling Chou; Debbie Chen; Barbara Sennino; Douglas Hanahan; Donald M McDonald
Increased vascular delivery and efficacy of chemotherapy after inhibition of platelet-derived growth factor-B.
The American journal of pathology 2011;178(6):2920-30.
2011: Nicole M Sodir; Lamorna Brown Swigart; Anthony N Karnezis; Douglas Hanahan; Gerard I Evan; Laura Soucek
Endogenous Myc maintains the tumor microenvironment.
Genes & development 2011;25(9):907-16.
2011: Eric A Collisson; Anguraj Sadanandam; Peter Olson; William J Gibb; Morgan Truitt; Shenda Gu; Janine Cooc; Jennifer Weinkle; Grace E Kim; Lakshmi Jakkula; Heidi S Feiler; Andrew H Ko; Adam B Olshen; Kathleen L Danenberg; Margaret A Tempero; Paul Spellman; Douglas Hanahan; Joe Gray
Subtypes of pancreatic ductal adenocarcinoma and their differing responses to therapy.
Nature medicine 2011;17(4):500-3.
2011: David Tuveson; Douglas Hanahan
Translational medicine: Cancer lessons from mice to humans.
Nature 2011;471(7338):316-7.
2011: Douglas Hanahan; Robert A Weinberg
Hallmarks of cancer: the next generation.
Cell 2011;144(5):646-74.
2010: Christopher W Chiu; Hiroaki Nozawa; Douglas Hanahan
Survival benefit with proapoptotic molecular and pathologic responses from dual targeting of mammalian target of rapamycin and epidermal growth factor receptor in a preclinical model of pancreatic neuroendocrine carcinogenesis.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2010;28(29):4425-33.
2010: Matthew G H Chun; Jian-Hua Mao; Christopher W Chiu; Allan Balmain; Douglas Hanahan
Polymorphic genetic control of tumor invasion in a mouse model of pancreatic neuroendocrine carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(40):17268-73.
2010: Matthew G H Chun; Douglas Hanahan
Genetic deletion of the desmosomal component desmoplakin promotes tumor microinvasion in a mouse model of pancreatic neuroendocrine carcinogenesis.
PLoS genetics 2010;6(9):.
2010: Seiko Ishida; Frank McCormick; Karen Smith-McCune; Douglas Hanahan
Enhancing tumor-specific uptake of the anticancer drug cisplatin with a copper chelator.
Cancer cell 2010;17(6):574-83.
2010: Danielle B Ulanet; Dale L Ludwig; C Ronald Kahn; Douglas Hanahan
Insulin receptor functionally enhances multistage tumor progression and conveys intrinsic resistance to IGF-1R targeted therapy.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(24):10791-8.
2010: Neta Erez; Morgan Truitt; Peter Olson; Sarah Tuttleton Arron; Douglas Hanahan
Cancer-Associated Fibroblasts Are Activated in Incipient Neoplasia to Orchestrate Tumor-Promoting Inflammation in an NF-kappaB-Dependent Manner.
Cancer cell 2010;17(2):135-47.
2010: Olivier Nolan-Stevaux; Peter Olson; Jessica C Pahler; Morgan C Truitt; Cristina Guinto; David C Lee; Douglas Hanahan
Differential contribution to neuroendocrine tumorigenesis of parallel egfr signaling in cancer cells and pericytes.
Genes & cancer 2010;1(2):125-41.
2010: Danielle B Ulanet; Douglas Hanahan
Loss of p19(Arf) facilitates the angiogenic switch and tumor initiation in a multi-stage cancer model via p53-dependent and independent mechanisms.
PloS one 2010;5(8):e12454.
2009: Kazuki N Sugahara; Tambet Teesalu; Priya Prakash Karmali; Venkata Ramana Kotamraju; Lilach Agemy; Olivier M Girard; Douglas Hanahan; Robert F Mattrey; Erkki Ruoslahti
Tissue-penetrating delivery of compounds and nanoparticles into tumors.
Cancer cell 2009;16(6):510-20.
2009: Peter Olson; Jun Lu; Hao Zhang; Anny Shai; Matthew G Chun; Yucheng Wang; Steven Libutti; Eric K Nakakura; Todd R Golub; Douglas Hanahan
MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer.
Genes & development 2009;23(18):2152-65.
2009: Peter Olson; Douglas Hanahan
Cancer. Breaching the cancer fortress.
Science (New York, N.Y.) 2009;324(5933):1400-1.
2009: Marta Pàez-Ribes; Elizabeth Allen; James Hudock; Takaaki Takeda; Hiroaki Okuyama; Francesc Viñals; Masahiro Inoue; Gabriele Bergers; Douglas Hanahan; Oriol Casanovas
Antiangiogenic therapy elicits malignant progression of tumors to increased local invasion and distant metastasis.
Cancer cell 2009;15(3):220-31.
2009: Jeffrey H Hager; Danielle B Ulanet; Lothar Hennighausen; Douglas Hanahan
Genetic ablation of Bcl-x attenuates invasiveness without affecting apoptosis or tumor growth in a mouse model of pancreatic neuroendocrine cancer.
PloS one 2009;4(2):e4455.
2009: Olivier Nolan-Stevaux; Janet Lau; Morgan L Truitt; Gerald Chu; Matthias Hebrok; Martin E Fernández-Zapico; Douglas Hanahan
GLI1 is regulated through Smoothened-independent mechanisms in neoplastic pancreatic ducts and mediates PDAC cell survival and transformation.
Genes & development 2009;23(1):24-36.
2008: Gabriele Bergers; Douglas Hanahan
Modes of resistance to anti-angiogenic therapy.
Nature reviews. Cancer 2008;8(8):592-603.
2008: Jessica C Pahler; Simon Tazzyman; Neta Erez; Yung-Yi Chen; Craig Murdoch; Hiroaki Nozawa; Claire E Lewis; Douglas Hanahan
Plasticity in tumor-promoting inflammation: impairment of macrophage recruitment evokes a compensatory neutrophil response.
Neoplasia (New York, N.Y.) 2008;10(4):329-40.
2008: Douglas Hanahan; Robert A. Weinberg
Retrospective: Judah Folkman (1933-2008).
Science (New York, N.Y.) 2008;319(5866):1055.
2008: Kristian Pietras; Jessica Pahler; Gabriele Bergers; Douglas Hanahan
Functions of paracrine PDGF signaling in the proangiogenic tumor stroma revealed by pharmacological targeting.
PLoS medicine 2008;5(1):e19.
2007: Yi-Chieh Nancy Du; Brian C Lewis; Douglas Hanahan; Harold Varmus
Assessing tumor progression factors by somatic gene transfer into a mouse model: Bcl-xL promotes islet tumor cell invasion.
PLoS biology 2007;5(10):e276.
2007: Douglas Hanahan; Erwin F Wagner; Richard D Palmiter
The origins of oncomice: a history of the first transgenic mice genetically engineered to develop cancer.
Genes & development 2007;21(18):2258-70.
2007: Katherine Marie Bell-McGuinn; Alfred L Garfall; Matthew Bogyo; Douglas Hanahan; Johanna A Joyce
Inhibition of cysteine cathepsin protease activity enhances chemotherapy regimens by decreasing tumor growth and invasiveness in a mouse model of multistage cancer.
Cancer research 2007;67(15):7378-85.
2006: Nabeel Bardeesy; Kuang-hung Cheng; Justin H Berger; Gerald Chu; Jessica Pahler; Peter Olson; Aram F Hezel; James Horner; Gregory Y Lauwers; Douglas Hanahan; Ronald A DePinho
Smad4 is dispensable for normal pancreas development yet critical in progression and tumor biology of pancreas cancer.
Genes & development 2006;20(22):3130-46.
2006: Hiroaki Nozawa; Christopher Chiu; Douglas Hanahan
Infiltrating neutrophils mediate the initial angiogenic switch in a mouse model of multistage carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(33):12493-8.
2006: Lianglin Zhang; Enrico Giraudo; Jason A Hoffman; Douglas Hanahan; Erkki Ruoslahti
Lymphatic zip codes in premalignant lesions and tumors.
Cancer research 2006;66(11):5696-706.
2006: Donald McDonald; Bert Vogelstein; Marie-Claire King; Waun Ki Hong; Hellmut Augustin; Douglas Hanahan; Marc Lippman
Wanted: cancer boss.
Nature 2006;440(7087):978-9.
2006: Nabeel Bardeesy; Andrew J Aguirre; Gerald Chu; Kuang-hung Cheng; Lyle V Lopez; Aram F Hezel; Bin Feng; Cameron Brennan; Ralph Weissleder; Umar Mahmood; Douglas Hanahan; Mark Redston; Lynda Chin; Ronald A DePinho
Both p16(Ink4a) and the p19(Arf)-p53 pathway constrain progression of pancreatic adenocarcinoma in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):5947-52.
2006: Vasilena Gocheva; Zeng Wei; Danxia Ke; David S Klimstra; Thomas Reinheckel; Christoph Peters; Douglas Hanahan; Johanna A Joyce
Distinct roles for cysteine cathepsin genes in multistage tumorigenesis.
Genes & development 2006;20(5):543-56.
2005: Oriol Casanovas; Jeffrey H Hager; Matthew Gee Hong Chun; Douglas Hanahan
Incomplete inhibition of the Rb tumor suppressor pathway in the context of inactivated p53 is sufficient for pancreatic islet tumorigenesis.
Oncogene 2005;24(44):6597-604.
2005: Oriol Casanovas; Daniel J Hicklin; Gabriele Bergers; Douglas Hanahan
Drug resistance by evasion of antiangiogenic targeting of VEGF signaling in late-stage pancreatic islet tumors.
Cancer cell 2005;8(4):299-309.
2005: Carlos A Garcia; Kamalaveni R Prabakar; Juan Diez; Zhu Alexander Cao; Gloria Allende; Markus Zeller; Rajpreet Dogra; Armando J Mendez; Eliot Rosenkranz; Ulf Dahl; Camillo Ricordi; Douglas Hanahan; Alberto Pugliese
Dendritic cells in human thymus and periphery display a proinsulin epitope in a transcription-dependent, capture-independent fashion.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2111-22.
2005: Johanna A Joyce; Craig Freeman; Nicole Meyer-Morse; Christopher R Parish; Douglas Hanahan
A functional heparan sulfate mimetic implicates both heparanase and heparan sulfate in tumor angiogenesis and invasion in a mouse model of multistage cancer.
Oncogene 2005;24(25):4037-51.
2005: Dylan Daniel; Christopher Chiu; Enrico Giraudo; Masahiro Inoue; Lee A Mizzen; N Randall Chu; Douglas Hanahan
CD4+ T cell-mediated antigen-specific immunotherapy in a mouse model of cervical cancer.
Cancer research 2005;65(5):2018-25.
2005: Kristian Pietras; Douglas Hanahan
A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(5):939-52.
2004: Johanna A Joyce; Douglas Hanahan
Multiple roles for cysteine cathepsins in cancer.
Cell cycle (Georgetown, Tex.) 2004;3(12):1516-619.
2004: David Argilla; Koei Chin; Mallika Singh; J Graeme Hodgson; Marcus W Bosenberg; Carlos Ortiz de Solórzano; Stephen Lockett; Ronald A DePinho; Joe Gray; Douglas Hanahan
Absence of telomerase and shortened telomeres have minimal effects on skin and pancreatic carcinogenesis elicited by viral oncogenes.
Cancer cell 2004;6(4):373-85.
2004: Sophie Astrof; Denise Crowley; Elizabeth L George; Tomohiko Fukuda; Kiyotoshi Sekiguchi; Douglas Hanahan; Richard O Hynes
Direct test of potential roles of EIIIA and EIIIB alternatively spliced segments of fibronectin in physiological and tumor angiogenesis.
Molecular and cellular biology 2004;24(19):8662-70.
2004: Enrico Giraudo; Masahiro Inoue; Douglas Hanahan
An amino-bisphosphonate targets MMP-9-expressing macrophages and angiogenesis to impair cervical carcinogenesis.
The Journal of clinical investigation 2004;114(5):623-33.
2004: Johanna A Joyce; Amos Baruch; Kareem A H Chehade; Nicole Meyer-Morse; Enrico Giraudo; Fong-Ying Tsai; Doron C Greenbaum; Jeffrey H Hager; Matthew Bogyo; Douglas Hanahan
Cathepsin cysteine proteases are effectors of invasive growth and angiogenesis during multistage tumorigenesis.
Cancer cell 2004;5(5):443-53.
2004: Jeffrey H Hager; J Graeme Hodgson; Jane Fridlyand; Sujatmi Hariono; Joe Gray; Douglas Hanahan
Oncogene expression and genetic background influence the frequency of DNA copy number abnormalities in mouse pancreatic islet cell carcinomas.
Cancer research 2004;64(7):2406-10.
2004: Donald M McDonald; Beverly A Teicher; William Stetler-Stevenson; Sylvia S W Ng; William D Figg; Judah Folkman; Douglas Hanahan; Robert Auerbach; Michael O'Reilly; Roy Herbst; David A Cheresh; Michael S Gordon; Alexander Eggermont; Steven Libutti
Report from the society for biological therapy and vascular biology faculty of the NCI workshop on angiogenesis monitoring.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2004;27(2):161-75.
2003: Johanna A Joyce; Pirjo Laakkonen; Michele Bernasconi; Gabriele Bergers; Erkki Ruoslahti; Douglas Hanahan
Stage-specific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis.
Cancer cell 2003;4(5):393-403.
2003: Jason A Hoffman; Enrico Giraudo; Mallika Singh; Lianglin Zhang; Masahiro Inoue; Kimmo Porkka; Douglas Hanahan; Erkki Ruoslahti
Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma.
Cancer cell 2003;4(5):383-91.
2003: Judy S Crabtree; Peter C Scacheri; Jerrold M Ward; Sara R McNally; Gary P Swain; Cristina Montagna; Jeffrey H Hager; Douglas Hanahan; Ulla Edlund; Mark Magnuson; Lisa Garrett-Beal; A Lee Burns; Thomas Ried; Settara C Chandrasekharappa; Stephen J Marx; Allen Spiegel; Francis S Collins
Of mice and MEN1: Insulinomas in a conditional mouse knockout.
Molecular and cellular biology 2003;23(17):6075-85.
2003: Douglas Hanahan; Antonio Lanzavecchia; Enrico Mihich
Fourteenth Annual Pezcoller Symposium: the novel dichotomy of immune interactions with tumors.
Cancer research 2003;63(11):3005-8.
2003: Gabriele Bergers; Steven Song; Nicole Meyer-Morse; Emily K Bergsland; Douglas Hanahan
Benefits of targeting both pericytes and endothelial cells in the tumor vasculature with kinase inhibitors.
The Journal of clinical investigation 2003;111(9):1287-95.
2003: Dylan Daniel; Nicole Meyer-Morse; Emily K Bergsland; Kerstin Dehne; Lisa M Coussens; Douglas Hanahan
Immune enhancement of skin carcinogenesis by CD4+ T cells.
The Journal of experimental medicine 2003;197(8):1017-28.
2002: Shan Man; Guido Bocci; Giulio Francia; Shane K Green; Serge Jothy; Douglas Hanahan; Peter Bohlen; Daniel J Hicklin; Gabriele Bergers; Robert S Kerbel
Antitumor effects in mice of low-dose (metronomic) cyclophosphamide administered continuously through the drinking water.
Cancer research 2002;62(10):2731-5.
2002: Zhu Alexander Cao; Dylan Daniel; Douglas Hanahan
Sub-lethal radiation enhances anti-tumor immunotherapy in a transgenic mouse model of pancreatic cancer.
BMC cancer 2002;2():11.
2002: Theresa Lopez; Douglas Hanahan
Elevated levels of IGF-1 receptor convey invasive and metastatic capability in a mouse model of pancreatic islet tumorigenesis.
Cancer cell 2002;1(4):339-53.
2002: Masahiro Inoue; Jeffrey H Hager; Napoleone Ferrara; Hans-Peter Gerber; Douglas Hanahan
VEGF-A has a critical, nonredundant role in angiogenic switching and pancreatic beta cell carcinogenesis.
Cancer cell 2002;1(2):193-202.
2002: Gabriele Bergers; Douglas Hanahan
Combining antiangiogenic agents with metronomic chemotherapy enhances efficacy against late-stage pancreatic islet carcinomas in mice.
Cold Spring Harbor symposia on quantitative biology 2002;67():293-300.
2001: G Hodgson; J H Hager; Stanislav Volik; Sujatmi Hariono; M Wernick; D Moore; N Nowak; Donna G Albertson; Daniel Pinkel; Colin Collins; Douglas Hanahan; Joe Gray
Genome scanning with array CGH delineates regional alterations in mouse islet carcinomas.
Nature genetics 2001;29(4):459-64.
2001: F Qian; Douglas Hanahan; Irving L Weissman
L-selectin can facilitate metastasis to lymph nodes in a transgenic mouse model of carcinogenesis.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3976-81.
2001: Gabriele Bergers; Douglas Hanahan
Cell factories for fighting cancer.
Nature biotechnology 2001;19(1):20-1.
2000: Lisa M Coussens; C L Tinkle; Douglas Hanahan; Zena Werb
MMP-9 supplied by bone marrow-derived cells contributes to skin carcinogenesis.
Cell 2000;103(3):481-90.
2000: Gabriele Bergers; Rolf Brekken; G McMahon; T H Vu; T Itoh; K Tamaki; K Tanzawa; P Thorpe; Shigeyoshi Itohara; Zena Werb; Douglas Hanahan
Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis.
Nature cell biology 2000;2(10):737-44.
2000: Y Shi; Jamil Kanaani; V Menard-Rose; Y H Ma; P Y Chang; Douglas Hanahan; A Tobin; G Grodsky; Steinunn Baekkeskov
Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion.
American journal of physiology. Endocrinology and metabolism 2000;279(3):E684-94.
2000: Douglas Hanahan
Benefits of bad telomeres.
Nature 2000;406(6796):573-4.
2000: Sanjiv A Luther; T Lopez; W Bai; Douglas Hanahan; Jason G Cyster
BLC expression in pancreatic islets causes B cell recruitment and lymphotoxin-dependent lymphoid neogenesis.
Immunity 2000;12(5):471-81.
2000: Douglas Hanahan; Gabriele Bergers; Emily K Bergsland
Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice.
The Journal of clinical investigation 2000;105(8):1045-7.
2000: Yun-Ping Zhou; JC Pena; Michael W Roe; AA Mittal; Matteo G Levisetti; Aaron C Baldwin; William Pugh; Diane Ostrega; N Ahmed; Vytautas P Bindokas; Louis H Philipson; Douglas Hanahan; Craig Thompson; Kenneth S Polonsky
Overexpression of Bcl-x(L) in beta-cells prevents cell death but impairs mitochondrial signal for insulin secretion.
American journal of physiology. Endocrinology and metabolism 2000;278(2):E340-51.
2000: Douglas Hanahan; Robert A. Weinberg
The hallmarks of cancer.
Cell 2000;100(1):57-70.
1999: Rohit N Kulkarni; Jonathon Winnay; M Daniels; Jens C Brüning; S N Flier; Douglas Hanahan; C Ronald Kahn
Altered function of insulin receptor substrate-1-deficient mouse islets and cultured beta-cell lines.
The Journal of clinical investigation 1999;104(12):R69-75.
1999: Lisa M Coussens; Wilfred W Raymond; Gabriele Bergers; M Laig-Webster; O Behrendtsen; Zena Werb; George H Caughey; Douglas Hanahan
Inflammatory mast cells up-regulate angiogenesis during squamous epithelial carcinogenesis.
Genes & development 1999;13(11):1382-97.
1999: Gabriele Bergers; Kashi Javaherian; Kin-Ming Lo; Judah Folkman; Douglas Hanahan
Effects of angiogenesis inhibitors on multistage carcinogenesis in mice.
Science (New York, N.Y.) 1999;284(5415):808-12.
1999: J Grunstein; W G Roberts; O Mathieu-Costello; Douglas Hanahan; R S Johnson
Tumor-derived expression of vascular endothelial growth factor is a critical factor in tumor expansion and vascular function.
Cancer research 1999;59(7):1592-8.
1999: J H Hager; Douglas Hanahan
Tumor cells utilize multiple pathways to down-modulate apoptosis. Lessons from a mouse model of islet cell carcinogenesis.
Annals of the New York Academy of Sciences 1999;887():150-63.
1998: Douglas Hanahan
Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity.
Current opinion in immunology 1998;10(6):656-62.
1998: R Ganss; Douglas Hanahan
Tumor microenvironment can restrict the effectiveness of activated antitumor lymphocytes.
Cancer research 1998;58(20):4673-81.
1998: D C Olson; C Deng; Douglas Hanahan
Fibroblast growth factor receptor 4, implicated in progression of islet cell carcinogenesis by its expression profile, does not contribute functionally.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1998;9(7):557-64.
1998: T H Vu; J Michael Shipley; Gabriele Bergers; J E Berger; Jill A Helms; Douglas Hanahan; Steven D Shapiro; Robert M Senior; Zena Werb
MMP-9/gelatinase B is a key regulator of growth plate angiogenesis and apoptosis of hypertrophic chondrocytes.
Cell 1998;93(3):411-22.
1998: Gavin Thurston; John W McLean; M Rizen; Peter Baluk; Amy Haskell; TJ Murphy; Douglas Hanahan; Donald M McDonald
Cationic liposomes target angiogenic endothelial cells in tumors and chronic inflammation in mice.
The Journal of clinical investigation 1998;101(7):1401-13.
1998: Gabriele Bergers; Douglas Hanahan; Lisa M Coussens
Angiogenesis and apoptosis are cellular parameters of neoplastic progression in transgenic mouse models of tumorigenesis.
The International journal of developmental biology 1998;42(7):995-1002.
1998: Douglas Hanahan
A flanking attack on cancer.
Nature medicine 1998;4(1):13-4.
1997: SF Kash; R S Johnson; Laurence H Tecott; Jeffrey L Noebels; R D Mayfield; Douglas Hanahan; Steinunn Baekkeskov
Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(25):14060-5.
1997: Y P Shi; G Mohapatra; J Miller; Douglas Hanahan; E Lander; P Gold; D Pinkel; Joe Gray
FISH probes for mouse chromosome identification.
Genomics 1997;45(1):42-7.
1997: K M Smith; D C Olson; R Hirose; Douglas Hanahan
Pancreatic gene expression in rare cells of thymic medulla: evidence for functional contribution to T cell tolerance.
International immunology 1997;9(9):1355-65.
1997: Annette Damert; Márcia Regina Machein; Georg Breier; M Q Fujita; Douglas Hanahan; Werner Risau; Karl H Plate
Up-regulation of vascular endothelial growth factor expression in a rat glioma is conferred by two distinct hypoxia-driven mechanisms.
Cancer research 1997;57(17):3860-4.
1997: DE Speiser; R Miranda; Arsen Zakarian; Martin F Bachmann; Kim J McKall-Faienza; Bernhard Odermatt; Douglas Hanahan; Rolf M Zinkernagel; Pamela S Ohashi
Self antigens expressed by solid tumors Do not efficiently stimulate naive or activated T cells: implications for immunotherapy.
The Journal of experimental medicine 1997;186(5):645-53.
1997: Douglas Hanahan
Signaling vascular morphogenesis and maintenance.
Science (New York, N.Y.) 1997;277(5322):48-50.
1997: Sang-Mo Kang; Darren B Schneider; Z Lin; Douglas Hanahan; David A Dichek; P G Stock; Steinunn Baekkeskov
Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction.
Nature medicine 1997;3(7):738-43.
1997: Y P Shi; P Naik; W F Dietrich; Joe Gray; Douglas Hanahan; Daniel Pinkel
DNA copy number changes associated with characteristic LOH in islet cell carcinomas of transgenic mice.
Genes, chromosomes & cancer 1997;19(2):104-11.
1997: Karen Smith-McCune; Y H Zhu; Douglas Hanahan; J Arbeit
Cross-species comparison of angiogenesis during the premalignant stages of squamous carcinogenesis in the human cervix and K14-HPV16 transgenic mice.
Cancer research 1997;57(7):1294-300.
1997: María A Blasco; H W Lee; M Rizen; Douglas Hanahan; Ronald A DePinho; Carol W Greider
Mouse models for the study of telomerase.
Ciba Foundation symposium 1997;211():160-70; discussion 170-6.
1996: Douglas Hanahan; G Christofori; P Naik; J Arbeit
Transgenic mouse models of tumour angiogenesis: the angiogenic switch, its molecular controls, and prospects for preclinical therapeutic models.
European journal of cancer (Oxford, England : 1990) 1996;32A(14):2386-93.
1996: Lisa M Coussens; Douglas Hanahan; J M Arbeit
Genetic predisposition and parameters of malignant progression in K14-HPV16 transgenic mice.
The American journal of pathology 1996;149(6):1899-917.
1996: J M Arbeit; D C Olson; Douglas Hanahan
Upregulation of fibroblast growth factors and their receptors during multi-stage epidermal carcinogenesis in K14-HPV16 transgenic mice.
Oncogene 1996;13(9):1847-57.
1996: P Naik; J Karrim; Douglas Hanahan
The rise and fall of apoptosis during multistage tumorigenesis: down-modulation contributes to tumor progression from angiogenic progenitors.
Genes & development 1996;10(17):2105-16.
1996: Douglas Hanahan; J Folkman
Patterns and emerging mechanisms of the angiogenic switch during tumorigenesis.
Cell 1996;86(3):353-64.
1996: R Johnson; B Spiegelman; Douglas Hanahan; R Wisdom
Cellular transformation and malignancy induced by ras require c-jun.
Molecular and cellular biology 1996;16(8):4504-11.
1996: J M Arbeit; Peter M Howley; Douglas Hanahan
Chronic estrogen-induced cervical and vaginal squamous carcinogenesis in human papillomavirus type 16 transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(7):2930-5.
1996: S Parangi; M O'Reilly; G Christofori; L Holmgren; J Grosfeld; J Folkman; Douglas Hanahan
Antiangiogenic therapy of transgenic mice impairs de novo tumor growth.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(5):2002-7.
1996: G K Gittes; P E Galante; Douglas Hanahan; W J Rutter; H T Debase
Lineage-specific morphogenesis in the developing pancreas: role of mesenchymal factors.
Development (Cambridge, England) 1996;122(2):439-47.
1996: María A Blasco; M Rizen; Carol W Greider; Douglas Hanahan
Differential regulation of telomerase activity and telomerase RNA during multi-stage tumorigenesis.
Nature genetics 1996;12(2):200-4.
1996: S V Onrust; P M Hartl; Steven D Rosen; Douglas Hanahan
Modulation of L-selectin ligand expression during an immune response accompanying tumorigenesis in transgenic mice.
The Journal of clinical investigation 1996;97(1):54-64.
1995: Peter J Hurlin; Kevin P Foley; Donald E Ayer; Robert N Eisenman; Douglas Hanahan; J M Arbeit
Regulation of Myc and Mad during epidermal differentiation and HPV-associated tumorigenesis.
Oncogene 1995;11(12):2487-501.
1995: S Parangi; W Dietrich; G Christofori; E S Lander; Douglas Hanahan
Tumor suppressor loci on mouse chromosomes 9 and 16 are lost at distinct stages of tumorigenesis in a transgenic model of islet cell carcinoma.
Cancer research 1995;55(24):6071-6.
1995: G Christofori; P Naik; Douglas Hanahan
Vascular endothelial growth factor and its receptors, flt-1 and flk-1, are expressed in normal pancreatic islets and throughout islet cell tumorigenesis.
Molecular endocrinology (Baltimore, Md.) 1995;9(12):1760-70.
1995: Irmgard Förster; R Hirose; J M Arbeit; Björn E Clausen; Douglas Hanahan
Limited capacity for tolerization of CD4+ T cells specific for a pancreatic beta cell neo-antigen.
Immunity 1995;2(6):573-85.
1995: G Christofori; P Naik; Douglas Hanahan
Deregulation of both imprinted and expressed alleles of the insulin-like growth factor 2 gene during beta-cell tumorigenesis.
Nature genetics 1995;10(2):196-201.
1995: M D Vivanco; R Johnson; P E Galante; Douglas Hanahan; Keith R Yamamoto
A transition in transcriptional activation by the glucocorticoid and retinoic acid receptors at the tumor stage of dermal fibrosarcoma development.
The EMBO journal 1995;14(10):2217-28.
1994: William F Dietrich; Eric H. Radany; J S Smith; John M Bishop; Douglas Hanahan; Eric S Lander
Genome-wide search for loss of heterozygosity in transgenic mouse tumors reveals candidate tumor suppressor genes on chromosomes 9 and 16.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(20):9451-5.
1994: T Yoshida; Douglas Hanahan
Murine pancreatic ductal adenocarcinoma produced by in vitro transduction of polyoma middle T oncogene into the islets of Langerhans.
The American journal of pathology 1994;145(3):671-84.
1994: C Jolicoeur; Douglas Hanahan; K M Smith
T-cell tolerance toward a transgenic beta-cell antigen and transcription of endogenous pancreatic genes in thymus.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(14):6707-11.
1994: J M Arbeit; K Münger; Peter M Howley; Douglas Hanahan
Progressive squamous epithelial neoplasia in K14-human papillomavirus type 16 transgenic mice.
Journal of virology 1994;68(7):4358-68.
1994: G Christofori; P Naik; Douglas Hanahan
A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis.
Nature 1994;369(6479):414-8.
1994: G Christofori; Douglas Hanahan
Molecular dissection of multi-stage tumorigenesis in transgenic mice.
Seminars in cancer biology 1994;5(1):3-12.
1994: P Naik; G Christofori; Douglas Hanahan
Insulin-like growth factor II is focally up-regulated and functionally involved as a second signal for oncogene-induced tumorigenesis.
Cold Spring Harbor symposia on quantitative biology 1994;59():459-70.
1994: Y H Ma; C Landis; N Tchao; J Wang; G Rodd; Douglas Hanahan; Henry R Bourne; G M Grodsky
Constitutively active stimulatory G-protein alpha s in beta-cells of transgenic mice causes counterregulation of the increased adenosine 3',5'-monophosphate and insulin secretion.
Endocrinology 1994;134(1):42-7.
1993: J C Hutton; G Christofori; W Y Chi; U Edman; P C Guest; Douglas Hanahan; R B Kelly
Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue.
Molecular endocrinology (Baltimore, Md.) 1993;7(9):1151-60.
1993: Gladys Teitelman; S Alpert; J M Polak; A Martinez; Douglas Hanahan
Precursor cells of mouse endocrine pancreas coexpress insulin, glucagon and the neuronal proteins tyrosine hydroxylase and neuropeptide Y, but not pancreatic polypeptide.
Development (Cambridge, England) 1993;118(4):1031-9.
1993: F Radvanyi; Stephan Christgau; Steinunn Baekkeskov; C Jolicoeur; Douglas Hanahan
Pancreatic beta cells cultured from individual preneoplastic foci in a multistage tumorigenesis pathway: a potentially general technique for isolating physiologically representative cell lines.
Molecular and cellular biology 1993;13(7):4223-32.
1993: J M Arbeit; K Münger; Peter M Howley; Douglas Hanahan
Neuroepithelial carcinomas in mice transgenic with human papillomavirus type 16 E6/E7 ORFs.
The American journal of pathology 1993;142(4):1187-97.
1993: Yuen Shing; G Christofori; Douglas Hanahan; Y Ono; R Sasada; K Igarashi; Judah Folkman
Betacellulin: a mitogen from pancreatic beta cell tumors.
Science (New York, N.Y.) 1993;259(5101):1604-7.
1992: Ella Bossy-Wetzel; R Bravo; Douglas Hanahan
Transcription factors junB and c-jun are selectively up-regulated and functionally implicated in fibrosarcoma development.
Genes & development 1992;6(12A):2340-51.
1992: M Tal; B Thorens; M Surana; Norman Fleischer; Harvey Lodish; Douglas Hanahan; S Efrat
Glucose transporter isotypes switch in T-antigen-transformed pancreatic beta cells growing in culture and in mice.
Molecular and cellular biology 1992;12(1):422-32.
1991: B A Hicks; R Stein; S Efrat; S Grant; Douglas Hanahan; Achilles A Demetriou
Transplantation of beta cells from transgenic mice into nude athymic diabetic rats restores glucose regulation.
Diabetes research and clinical practice 1991;14(3):157-64.
1991: J Kandel; Ella Bossy-Wetzel; F Radvanyi; Michael Klagsbrun; Judah Folkman; Douglas Hanahan
Neovascularization is associated with a switch to the export of bFGF in the multistep development of fibrosarcoma.
Cell 1991;66(6):1095-104.
1991: S G Grant; I Seidman; Douglas Hanahan; V L Bautch
Early invasiveness characterizes metastatic carcinoid tumors in transgenic mice.
Cancer research 1991;51(18):4917-23.
1991: Douglas Hanahan; J Jessee; F R Bloom
Plasmid transformation of Escherichia coli and other bacteria.
Methods in enzymology 1991;204():63-113.
1991: J Folkman; Douglas Hanahan
Switch to the angiogenic phenotype during tumorigenesis.
Princess Takamatsu symposia 1991;22():339-47.
1991: B B Knowles; S Faas; A Juretic; N Fox; R Crooke; Douglas Hanahan; D Solter; L Jewett
SV40 T antigen transgenic mice: cytotoxic T lymphocytes as a selective force in tumor progression.
Basic life sciences 1991;57():111-24; discussion 125.
1990: Jacek Skowronski; C Jolicoeur; S Alpert; Douglas Hanahan
Determinants of the B-cell response against a transgenic autoantigen.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(19):7487-91.
1990: S G Grant; J Jessee; F R Bloom; Douglas Hanahan
Differential plasmid rescue from transgenic mouse DNAs into Escherichia coli methylation-restriction mutants.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(12):4645-9.
1990: S Efrat; Norman Fleischer; Douglas Hanahan
Diabetes induced in male transgenic mice by expression of human H-ras oncoprotein in pancreatic beta cells.
Molecular and cellular biology 1990;10(4):1779-83.
1990: A C Powers; S Efrat; S Mojsov; D Spector; Joel F Habener; Douglas Hanahan
Proglucagon processing similar to normal islets in pancreatic alpha-like cell line derived from transgenic mouse tumor.
Diabetes 1990;39(4):406-14.
1990: Douglas Hanahan
Transgenic mouse models of self-tolerance and autoreactivity by the immune system.
Annual review of cell biology 1990;6():493-537.
1989: Douglas Hanahan
Transgenic mice as probes into complex systems.
Science (New York, N.Y.) 1989;246(4935):1265-75.
1989: Robert H Edwards; W J Rutter; Douglas Hanahan
Directed expression of NGF to pancreatic beta cells in transgenic mice leads to selective hyperinnervation of the islets.
Cell 1989;58(1):161-70.
1989: Valerie Lindgren; M Sippola-Thiele; Jacek Skowronski; E Wetzel; Peter M Howley; Douglas Hanahan
Specific chromosomal abnormalities characterize fibrosarcomas of bovine papillomavirus type 1 transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(13):5025-9.
1989: Judah Folkman; K Watson; Donald Ingber; Douglas Hanahan
Induction of angiogenesis during the transition from hyperplasia to neoplasia.
Nature 1989;339(6219):58-61.
1989: M Sippola-Thiele; Douglas Hanahan; Peter M Howley
Cell-heritable stages of tumor progression in transgenic mice harboring the bovine papillomavirus type 1 genome.
Molecular and cellular biology 1989;9(3):925-34.
1989: V L Bautch; S Toda; J A Hassell; Douglas Hanahan
Tissue specificity of oncogene action: endothelial cell tumours in polyoma middle T transgenic mice.
IARC scientific publications 1989;(96):255-66.
1989: Douglas Hanahan; E Wetzel; Jacek Skowronski; M Sippola-Thiele; Valerie Lindgren; Peter M Howley
Tumorigenic latency and separable stages during fibrosarcoma development in transgenic mice carrying papillomavirus genomes.
Princess Takamatsu symposia 1989;20():289-96.
1989: Douglas Hanahan; C Jolicoeur; S Alpert; Jacek Skowronski
Alternative self or nonself recognition of an antigen expressed in a rare cell type in transgenic mice: implications for self-tolerance and autoimmunity.
Cold Spring Harbor symposia on quantitative biology 1989;54 Pt 2():821-35.
1989: S Efrat; Douglas Hanahan
Evidence for threshold effects in transformation of pancreatic beta cells by SV40 T antigen in transgenic mice.
Current topics in microbiology and immunology 1989;144():89-95.
1989: Majambu Mbikay; S G Grant; F Sirois; H Tadros; J Skowronski; C Lazure; Nabil G Seidah; Douglas Hanahan; Michel Chrétien
cDNA sequence of neuroendocrine protein 7B2 expressed in beta cell tumors of transgenic mice.
International journal of peptide and protein research 1989;33(1):39-45.
1988: S Efrat; S Linde; Hans Kofod; D Spector; M Delannoy; S Grant; Douglas Hanahan; Steinunn Baekkeskov
Beta-cell lines derived from transgenic mice expressing a hybrid insulin gene-oncogene.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(23):9037-41.
1988: R Holm; Ian Varndell; R F Power; Anne E Bishop; O D Madsen; S Alpert; Douglas Hanahan; Julia M Polak
Ultrastructure and electron immunocytochemistry of insulin-producing B-cell tumors from transgenic mice: comparison with counterpart human tumors.
Ultrastructural pathology 1988;12(5):547-59.
1988: S Efrat; Gladys Teitelman; M Anwar; D Ruggiero; Douglas Hanahan
Glucagon gene regulatory region directs oncoprotein expression to neurons and pancreatic alpha cells.
Neuron 1988;1(7):605-13.
1988: S Alpert; Douglas Hanahan; Gladys Teitelman
Hybrid insulin genes reveal a developmental lineage for pancreatic endocrine cells and imply a relationship with neurons.
Cell 1988;53(2):295-308.
1988: E A Raleigh; N E Murray; H Revel; Robert Blumenthal; D Westaway; A D Reith; P W Rigby; J Elhai; Douglas Hanahan
McrA and McrB restriction phenotypes of some E. coli strains and implications for gene cloning.
Nucleic acids research 1988;16(4):1563-75.
1988: Gladys Teitelman; S Alpert; Douglas Hanahan
Proliferation, senescence, and neoplastic progression of beta cells in hyperplasic pancreatic islets.
Cell 1988;52(1):97-105.
1988: Douglas Hanahan
Dissecting multistep tumorigenesis in transgenic mice.
Annual review of genetics 1988;22():479-519.
1987: V L Bautch; S Toda; J A Hassell; Douglas Hanahan
Endothelial cell tumors develop in transgenic mice carrying polyoma virus middle T oncogene.
Cell 1987;51(4):529-37.
1987: S Efrat; Steinunn Baekkeskov; D Lane; Douglas Hanahan
Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes.
The EMBO journal 1987;6(9):2699-704.
1987: T E Adams; S Alpert; Douglas Hanahan
Non-tolerance and autoantibodies to a transgenic self antigen expressed in pancreatic beta cells.
Nature 1987;325(6101):223-8.
1987: David M Helfman; J C Fiddes; Douglas Hanahan
Directional cDNA cloning in plasmid vectors by sequential addition of oligonucleotide linkers.
Methods in enzymology 1987;152():349-59.
1987: S Efrat; Douglas Hanahan
Bidirectional activity of the rat insulin II 5'-flanking region in transgenic mice.
Molecular and cellular biology 1987;7(1):192-8.
1987: R F Power; R Holm; Anne E Bishop; Ian Varndell; S Alpert; Douglas Hanahan; Julia M Polak
Transgenic mouse model: a new approach for the investigation of endocrine pancreatic B-cell growth.
Gut 1987;28 Suppl():121-9.
1986: J Sambrook; Douglas Hanahan; L Rodgers; M J Gething
Expression of human tissue-type plasminogen activator from lytic viral vectors and in established cell lines.
Molecular biology & medicine 1986;3(6):459-81.
1986: M Lacey; S Alpert; Douglas Hanahan
Bovine papillomavirus genome elicits skin tumours in transgenic mice.
Nature 1986;322(6080):609-12.
1985: Douglas Hanahan
Heritable formation of pancreatic beta-cell tumours in transgenic mice expressing recombinant insulin/simian virus 40 oncogenes.
Nature 1985;315(6015):115-22.
1984: Douglas Hanahan
Oncogenes in transgenic mice.
Nature 1984;312(5994):503-4.
1984: K Van Doren; Douglas Hanahan; Y Gluzman
Infection of eucaryotic cells by helper-independent recombinant adenoviruses: early region 1 is not obligatory for integration of viral DNA.
Journal of virology 1984;50(2):606-14.
1984: Douglas Hanahan; Y Gluzman
Rescue of functional replication origins from embedded configurations in a plasmid carrying the adenovirus genome.
Molecular and cellular biology 1984;4(2):302-9.
1983: Douglas Hanahan
Studies on transformation of Escherichia coli with plasmids.
Journal of molecular biology 1983;166(4):557-80.
1983: Douglas Hanahan; M Meselson
Plasmid screening at high colony density.
Methods in enzymology 1983;100():333-42.
1981: J Wozney; Douglas Hanahan; V Tate; H Boedtker; P Doty
Structure of the pro alpha 2 (I) collagen gene.
Nature 1981;294(5837):129-35.
1981: J Wozney; Douglas Hanahan; R Morimoto; H Boedtker; P Doty
Fine structural analysis of the chicken pro alpha 2 collagen gene.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(2):712-6.
1980: M Perucho; Douglas Hanahan; Michael Wigler
Genetic and physical linkage of exogenous sequences in transformed cells.
Cell 1980;22(1 Pt 1):309-17.
1980: Douglas Hanahan; D S Auld
Low temperature stopped-flow spectrometry.
Analytical biochemistry 1980;108(1):86-95.
1980: Douglas Hanahan; D Lane; L Lipsich; Michael Wigler; Michael R Botchan
Characteristics of an SV40-plasmid recombinant and its movement into and out of the genome of a murine cell.
Cell 1980;21(1):127-39.
1980: Douglas Hanahan; M Meselson
Plasmid screening at high colony density.
Gene 1980;10(1):63-7.
1980: M Perucho; Douglas Hanahan; L Lipsich; Michael Wigler
Isolation of the chicken thymidine kinase gene by plasmid rescue.
Nature 1980;285(5762):207-10.
1979: H Lehrach; A M Frischauf; Douglas Hanahan; J Wozney; F Fuller; H Boedtker
Construction and characterization of pro alpha 1 collagen complementary deoxyribonucleic acid clones.
Biochemistry 1979;18(14):3146-52.
1978: H Lehrach; A M Frischauf; Douglas Hanahan; J Wozney; F Fuller; R Crkvenjakov; H Boedtker; P Doty
Construction and characterization of a 2.5-kilobase procollagen clone.
Proceedings of the National Academy of Sciences of the United States of America 1978;75(11):5417-21.