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Spyros Artavanis-Tsakonas

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Sanja Sale; Daniel Lafkas; Spyros Artavanis-Tsakonas
Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages.
Robert J Fleming; Kazuya Hori; Jillian M Langer; Spyros Artavanis-Tsakonas; Gina V Filloramo; Robert A Obar; Anindya Sen; Ayiti C Maharaj-Best
An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling.
K G Guruharsha; R T Krishnan; Julian Mintseris; Bob Obar; KV VijayRaghavan; K Aishwarya; Spyros Artavanis-Tsakonas
Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions.

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All Publications

2013: Sanja Sale; Daniel Lafkas; Spyros Artavanis-Tsakonas
Notch2 genetic fate mapping reveals two previously unrecognized mammary epithelial lineages.
Nature cell biology 2013;15(5):451-60.
2013: Robert J Fleming; Kazuya Hori; Jillian M Langer; Spyros Artavanis-Tsakonas; Gina V Filloramo; Robert A Obar; Anindya Sen; Ayiti C Maharaj-Best
An extracellular region of Serrate is essential for ligand-induced cis-inhibition of Notch signaling.
Development (Cambridge, England) 2013;140(9):2039-49.
2012: K G Guruharsha; R T Krishnan; Julian Mintseris; Bob Obar; KV VijayRaghavan; K Aishwarya; Spyros Artavanis-Tsakonas
Drosophila protein interaction map (DPiM): a paradigm for metazoan protein complex interactions.
Fly 2012;6(4):246-53.
2012: K G Guruharsha; Mark W Kankel; Spyros Artavanis-Tsakonas
The Notch signalling system: recent insights into the complexity of a conserved pathway.
Nature reviews. Genetics 2012;13(9):654-66.
2012: Kazuya Hori; Tomas Kirchhausen; Anindya Sen; Spyros Artavanis-Tsakonas
Regulation of ligand-independent Notch signal through intracellular trafficking.
Communicative & integrative biology 2012;5(4):374-6.
2012: S K Pallavi; Chindo Hicks; Diana M Ho; Lucio Miele; Spyros Artavanis-Tsakonas
Notch and Mef2 synergize to promote proliferation and metastasis through JNK signal activation in Drosophila.
The EMBO journal 2012;31(13):2895-907.
2012: Angeliki Louvi; Spyros Artavanis-Tsakonas
Notch and disease: a growing field.
Seminars in cell & developmental biology 2012;23(4):473-80.
2011: K G Guruharsha; Steven P Gygi; Bhaveen Kapadia; Emily McKillip; Julian Mintseris; Bob Obar; Bayan Parsa; David Y Rhee; Jean-François Rual; Saumini Shah; Mark Stapleton; Namita Vaidya; Pujita Vaidya; KV VijayRaghavan; Kenneth H Wan; Christina Wong; Charles Yu; Bo Zhai; Chapman Beekman; Joseph W Carlson; Susan E Celniker; Odise Cenaj; Xiao Chen; Spyros Artavanis-Tsakonas
A protein complex network of Drosophila melanogaster.
Cell 2011;147(3):690-703.
2011: Joseph F Arboleda-Velasquez; Jan Manent; Jeong Hyun Lee; Saara Tikka; Carolina Ospina; Charles R Vanderburg; Matthew P Frosch; Manuel Rodríguez-Falcón; Judit Villen; Steven Gygi; Francisco Lopera; Hannu Kalimo; Michael A Moskowitz; Cenk Ayata; Angeliki Louvi; Spyros Artavanis-Tsakonas
Hypomorphic Notch 3 alleles link Notch signaling to ischemic cerebral small-vessel disease.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(21):E128-35.
2011: Youping Sun; Malgorzata Klauzinska; Robert J Lake; Joseph M Lee; Stefania Santopietro; Ahmed Raafat; David Salomon; Robert Callahan; Spyros Artavanis-Tsakonas
Trp53 regulates Notch 4 signaling through Mdm2.
Journal of cell science 2011;124(Pt 7):1067-76.
2011: Anindya Sen; Takakazu Yokokura; Mark W Kankel; Douglas N Dimlich; Jan Manent; Subhabrata Sanyal; Spyros Artavanis-Tsakonas
Modeling spinal muscular atrophy in Drosophila links Smn to FGF signaling.
The Journal of cell biology 2011;192(3):481-95.
2011: Silvia Fre; Jeffrey Greve; Edouard Hannezo; Mathilde Huyghe; Holger Kissel; Daniel Lafkas; Daniel Louvard; Angeliki Louvi; Sanja Sale; Spyros Artavanis-Tsakonas
Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.
PloS one 2011;6(10):e25785.
2010: Maria Dimitriadi; James N Sleigh; Amy Walker; Howard C Chang; Anindya Sen; Geetika Kalloo; Jevede Harris; Tom Barsby; Melissa B Walsh; John S Satterlee; Chris Li; David Van Vactor; Spyros Artavanis-Tsakonas; Anne C Hart
Conserved genes act as modifiers of invertebrate SMN loss of function defects.
PLoS genetics 2010;6(10):e1001172.
2010: Marco Mazzone; Laura M Selfors; John Albeck; Michael Overholtzer; Sanja Sale; Danielle L Carroll; Darshan Pandya; Yiling Lu; Gordon B Mills; Jon C Aster; Spyros Artavanis-Tsakonas; Joan S Brugge
Dose-dependent induction of distinct phenotypic responses to Notch pathway activation in mammary epithelial cells.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(11):5012-7.
2010: Spyros Artavanis-Tsakonas; Marc A T Muskavitch
Notch: the past, the present, and the future.
Current topics in developmental biology 2010;92():1-29.
2010: Deborah F Kelly; Robert J Lake; Teije C Middelkoop; Hua-Ying Fan; Spyros Artavanis-Tsakonas; Thomas Walz
Molecular structure and dimeric organization of the Notch extracellular domain as revealed by electron microscopy.
PloS one 2010;5(5):e10532.
2009: Silvia Fre; S K Pallavi; Mathilde Huyghe; Marick Laé; Klaus-Peter Janssen; Sylvie Robine; Spyros Artavanis-Tsakonas; Daniel Louvard
Notch and Wnt signals cooperatively control cell proliferation and tumorigenesis in the intestine.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(15):6309-14.
2009: Gregory D Hurlbut; Mark W Kankel; Spyros Artavanis-Tsakonas
Nodal points and complexity of Notch-Ras signal integration.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(7):2218-23.
2009: Robert J Lake; Lisa M Grimm; Alexey Veraksa; Andrew Banos; Spyros Artavanis-Tsakonas
In vivo analysis of the Notch receptor S1 cleavage.
PloS one 2009;4(8):e6728.
2008: Joseph F Arboleda-Velasquez; Zhipeng Zhou; Hwa Kyoung Shin; Angeliki Louvi; Hyung-Hwan Kim; Sean I Savitz; James K Liao; Salvatore Salomone; Cenk Ayata; Michael A Moskowitz; Spyros Artavanis-Tsakonas
Linking Notch signaling to ischemic stroke.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(12):4856-61.
2008: Howard Chia-Hao Chang; Douglas N Dimlich; Takakazu Yokokura; Ashim Mukherjee; Mark W Kankel; Anindya Sen; Vasanthi Sridhar; Tudor A Fulga; Anne C Hart; David Van Vactor; Spyros Artavanis-Tsakonas
Modeling spinal muscular atrophy in Drosophila.
PloS one 2008;3(9):e3209.
2008: Anna M Bentley; Spyros Artavanis-Tsakonas; Jennifer S Stanford
Nanocourses: a short course format as an educational tool in a biological sciences graduate curriculum.
CBE life sciences education 2008;7(2):175-83.
2007: Mark W Kankel; Gregory D Hurlbut; Geeta Upadhyay; Vijay Yajnik; Barry Yedvobnick; Spyros Artavanis-Tsakonas
Investigating the genetic circuitry of mastermind in Drosophila, a notch signal effector.
Genetics 2007;177(4):2493-505.
2007: Deborah F Kelly; Robert J Lake; Thomas Walz; Spyros Artavanis-Tsakonas
Conformational variability of the intracellular domain of Drosophila Notch and its interaction with Suppressor of Hairless.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(23):9591-6.
2007: Gregory D Hurlbut; Mark W Kankel; Robert J Lake; Spyros Artavanis-Tsakonas
Crossing paths with Notch in the hyper-network.
Current opinion in cell biology 2007;19(2):166-75.
2006: Apostolos Klinakis; Matthias Szabolcs; Katerina Politi; Hippokratis Kiaris; Spyros Artavanis-Tsakonas; Argiris Efstratiadis
Myc is a Notch1 transcriptional target and a requisite for Notch1-induced mammary tumorigenesis in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9262-7.
2006: Angeliki Louvi; Spyros Artavanis-Tsakonas
Notch signalling in vertebrate neural development.
Nature reviews. Neuroscience 2006;7(2):93-102.
2006: Philippos Mourikis; Gregory D Hurlbut; Spyros Artavanis-Tsakonas
Enigma, a mitochondrial protein affecting lifespan and oxidative stress response in Drosophila.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1307-12.
2006: Angeliki Louvi; Joseph F Arboleda-Velasquez; Spyros Artavanis-Tsakonas
CADASIL: a critical look at a Notch disease.
Developmental neuroscience 2006;28(1-2):5-12.
2005: Ashim Mukherjee; Alexey Veraksa; Andreas Bauer; Carine Rosse; Jacques Camonis; Spyros Artavanis-Tsakonas
Regulation of Notch signalling by non-visual beta-arrestin.
Nature cell biology 2005;7(12):1191-201.
2005: Sylvie Robine; Silvia Fre; Mathilde Huyghe; Spyros Artavanis-Tsakonas; Daniel Louvard
[Notch signals control the fate of immature progenitor cells in the intestine].
Médecine sciences : M/S 2005;21(8-9):780-2.
2005: Silvia Fre; Mathilde Huyghe; Philippos Mourikis; Sylvie Robine; Daniel Louvard; Spyros Artavanis-Tsakonas
Notch signals control the fate of immature progenitor cells in the intestine.
Nature 2005;435(7044):964-8.
2005: Alexey Veraksa; Andreas Bauer; Spyros Artavanis-Tsakonas
Analyzing protein complexes in Drosophila with tandem affinity purification-mass spectrometry.
Developmental dynamics : an official publication of the American Association of Anatomists 2005;232(3):827-34.
2004: Hippokratis Kiaris; Katerina Politi; Lisa M Grimm; Matthias Szabolcs; Peter Fisher; Argiris Efstratiadis; Spyros Artavanis-Tsakonas
Modulation of notch signaling elicits signature tumors and inhibits hras1-induced oncogenesis in the mouse mammary epithelium.
The American journal of pathology 2004;165(2):695-705.
2004: Kenneth H Moberg; Ashim Mukherjee; Alexey Veraksa; Spyros Artavanis-Tsakonas; Iswar K Hariharan
The Drosophila F box protein archipelago regulates dMyc protein levels in vivo.
Current biology : CB 2004;14(11):965-74.
2004: Spyros Artavanis-Tsakonas
Accessing the Exelixis collection.
Nature genetics 2004;36(3):207.
2003: Luc Grandbarbe; Julien Bouissac; Matt Rand; Martin Hrabé De Angelis; Spyros Artavanis-Tsakonas; Eliane Mohier
Delta-Notch signaling controls the generation of neurons/glia from neural stem cells in a stepwise process.
Development (Cambridge, England) 2003;130(7):1391-402.
2003: Sergi Beltran; Enrique Blanco; Florenci Serras; Beatriz Pérez-Villamil; Roderic Guigó; Spyros Artavanis-Tsakonas; Montserrat Corominas
Transcriptional network controlled by the trithorax-group gene ash2 in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(6):3293-8.
2002: Ketu Mishra-Gorur; Matthew D Rand; Beatriz Perez-Villamil; Spyros Artavanis-Tsakonas
Down-regulation of Delta by proteolytic processing.
The Journal of cell biology 2002;159(2):313-24.
2002: Kenji Matsuno; Mikiko Ito; Kazuya Hori; Fumiyasu Miyashita; Satoshi Suzuki; Noriyuki Kishi; Spyros Artavanis-Tsakonas; Hideyuki Okano
Involvement of a proline-rich motif and RING-H2 finger of Deltex in the regulation of Notch signaling.
Development (Cambridge, England) 2002;129(4):1049-59.
2002: Hippokratis Kiaris; Andrew V Schally; Rebeca Busto; Gabor Halmos; Spyros Artavanis-Tsakonas; Jozsef Varga
Expression of a splice variant of the receptor for GHRH in 3T3 fibroblasts activates cell proliferation responses to GHRH analogs.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(1):196-200.
2001: N Kishi; Z Tang; Yusuke Maeda; A Hirai; R Mo; M Ito; S Suzuki; Kazuwa Nakao; Taroh Kinoshita; Tom Kadesch; C c Hui; Spyros Artavanis-Tsakonas; Hideyuki Okano; K Matsuno
Murine homologs of deltex define a novel gene family involved in vertebrate Notch signaling and neurogenesis.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2001;19(1):21-35.
2000: L Wu; J C Aster; Stephen C Blacklow; R Lake; Spyros Artavanis-Tsakonas; James D Griffin
MAML1, a human homologue of Drosophila mastermind, is a transcriptional co-activator for NOTCH receptors.
Nature genetics 2000;26(4):484-9.
2000: Matthew D Rand; L M Grimm; Spyros Artavanis-Tsakonas; Vytas Patriub; Stephen C Blacklow; J Sklar; Jon C Aster
Calcium depletion dissociates and activates heterodimeric notch receptors.
Molecular and cellular biology 2000;20(5):1825-35.
2000: Shoichiro Kurata; MJ Go; Spyros Artavanis-Tsakonas; W J Gehring
Notch signaling and the determination of appendage identity.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2117-22.
1999: Nenad Sestan; Spyros Artavanis-Tsakonas; Pasko Rakic
Contact-dependent inhibition of cortical neurite growth mediated by notch signaling.
Science (New York, N.Y.) 1999;286(5440):741-6.
1999: K Purcell; Spyros Artavanis-Tsakonas
The developmental role of warthog, the notch modifier encoding Drab6.
The Journal of cell biology 1999;146(4):731-40.
1999: Spyros Artavanis-Tsakonas; Matthew D Rand; Robert J Lake
Notch signaling: cell fate control and signal integration in development.
Science (New York, N.Y.) 1999;284(5415):770-6.
1999: Glenda E Gray; R S Mann; E Mitsiadis; Domingos Henrique; Maria Luisa Carcangiu; A Banks; J Leiman; D Ward; D Ish-Horowitz; Spyros Artavanis-Tsakonas
Human ligands of the Notch receptor.
The American journal of pathology 1999;154(3):785-94.
1999: H Qi; M D Rand; X Wu; Nenad Sestan; W Wang; Pasko Rakic; Tian Xu; Spyros Artavanis-Tsakonas
Processing of the notch ligand delta by the metalloprotease Kuzbanian.
Science (New York, N.Y.) 1999;283(5398):91-4.
1998: MJ Go; Spyros Artavanis-Tsakonas
A genetic screen for novel components of the notch signaling pathway during Drosophila bristle development.
Genetics 1998;150(1):211-20.
1998: MJ Go; DS Eastman; Spyros Artavanis-Tsakonas
Cell proliferation control by Notch signaling in Drosophila development.
Development (Cambridge, England) 1998;125(11):2031-40.
1998: K Matsuno; DS Eastman; T Mitsiades; AM Quinn; M L Carcanciu; P Ordentlich; Tom Kadesch; Spyros Artavanis-Tsakonas
Human deltex is a conserved regulator of Notch signalling.
Nature genetics 1998;19(1):74-8.
1998: P Ordentlich; A Lin; Chun-Pyn Shen; CM Blaumueller; K Matsuno; Spyros Artavanis-Tsakonas; Tom Kadesch
Notch inhibition of E47 supports the existence of a novel signaling pathway.
Molecular and cellular biology 1998;18(4):2230-9.
1997: Robert J Fleming; K Purcell; Spyros Artavanis-Tsakonas
The NOTCH receptor and its ligands.
Trends in cell biology 1997;7(11):437-41.
1997: Anthony John Capobianco; Panayiotis Zagouras; CM Blaumueller; Spyros Artavanis-Tsakonas; John M Bishop
Neoplastic transformation by truncated alleles of human NOTCH1/TAN1 and NOTCH2.
Molecular and cellular biology 1997;17(11):6265-73.
1997: K Matsuno; MJ Go; X Sun; DS Eastman; Spyros Artavanis-Tsakonas
Suppressor of Hairless-independent events in Notch signaling imply novel pathway elements.
Development (Cambridge, England) 1997;124(21):4265-73.
1997: Stewart Frankel; E A Sigel; C Craig; Sarah C R Elgin; Mark S Mooseker; Spyros Artavanis-Tsakonas
An actin-related protein in Drosophila colocalizes with heterochromatin protein 1 in pericentric heterochromatin.
Journal of cell science 1997;110 ( Pt 17)():1999-2012.
1997: X Sun; Spyros Artavanis-Tsakonas
Secreted forms of DELTA and SERRATE define antagonists of Notch signaling in Drosophila.
Development (Cambridge, England) 1997;124(17):3439-48.
1997: CM Blaumueller; H Qi; Panayiotis Zagouras; Spyros Artavanis-Tsakonas
Intracellular cleavage of Notch leads to a heterodimeric receptor on the plasma membrane.
Cell 1997;90(2):281-91.
1997: CM Blaumueller; Spyros Artavanis-Tsakonas
Comparative aspects of Notch signaling in lower and higher eukaryotes.
Perspectives on developmental neurobiology 1997;4(4):325-43.
1996: Esther Verheyen; K J Purcell; M E Fortini; Spyros Artavanis-Tsakonas
Analysis of dominant enhancers and suppressors of activated Notch in Drosophila.
Genetics 1996;144(3):1127-41.
1996: X Sun; Spyros Artavanis-Tsakonas
The intracellular deletions of Delta and Serrate define dominant negative forms of the Drosophila Notch ligands.
Development (Cambridge, England) 1996;122(8):2465-74.
1996: Y Liu; G Dehni; K J Purcell; J Sokolow; Maria Luisa Carcangiu; Spyros Artavanis-Tsakonas; Stefano Stifani
Epithelial expression and chromosomal location of human TLE genes: implications for notch signaling and neoplasia.
Genomics 1996;31(1):58-64.
1995: K Matsuno; R J Diederich; MJ Go; CM Blaumueller; Spyros Artavanis-Tsakonas
Deltex acts as a positive regulator of Notch signaling through interactions with the Notch ankyrin repeats.
Development (Cambridge, England) 1995;121(8):2633-44.
1995: Panayiotis Zagouras; Stefano Stifani; CM Blaumueller; Maria Luisa Carcangiu; Spyros Artavanis-Tsakonas
Alterations in Notch signaling in neoplastic lesions of the human cervix.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(14):6414-8.
1995: I A Dawson; S Roth; Spyros Artavanis-Tsakonas
The Drosophila cell cycle gene fizzy is required for normal degradation of cyclins A and B during mitosis and has homology to the CDC20 gene of Saccharomyces cerevisiae.
The Journal of cell biology 1995;129(3):725-37.
1995: Spyros Artavanis-Tsakonas; K Matsuno; M E Fortini
Notch signaling.
Science (New York, N.Y.) 1995;268(5208):225-32.
1994: M E Fortini; Spyros Artavanis-Tsakonas
The suppressor of hairless protein participates in notch receptor signaling.
Cell 1994;79(2):273-82.
1994: H K Hing; X Sun; Spyros Artavanis-Tsakonas
Modulation of wingless signaling by Notch in Drosophila.
Mechanisms of development 1994;47(3):261-8.
1994: N S Morgan; D M Skovronsky; Spyros Artavanis-Tsakonas; Mark S Mooseker
The molecular cloning and characterization of Drosophila melanogaster myosin-IA and myosin-IB.
Journal of molecular biology 1994;239(3):347-56.
1994: Richard G Fehon; I A Dawson; Spyros Artavanis-Tsakonas
A Drosophila homologue of membrane-skeleton protein 4.1 is associated with septate junctions and is encoded by the coracle gene.
Development (Cambridge, England) 1994;120(3):545-57.
1994: R J Diederich; K Matsuno; H Hing; Spyros Artavanis-Tsakonas
Cytosolic interaction between deltex and Notch ankyrin repeats implicates deltex in the Notch signaling pathway.
Development (Cambridge, England) 1994;120(3):473-81.
1994: Isabelle Busseau; R J Diederich; T Xu; Spyros Artavanis-Tsakonas
A member of the Notch group of interacting loci, deltex encodes a cytoplasmic basic protein.
Genetics 1994;136(2):585-96.
1994: S Frankel; M B Heintzelman; Spyros Artavanis-Tsakonas; Mark S Mooseker
Identification of a divergent actin-related protein in Drosophila.
Journal of molecular biology 1994;235(4):1351-6.
1993: M E Fortini; Spyros Artavanis-Tsakonas
Notch: neurogenesis is only part of the picture.
Cell 1993;75(7):1245-7.
1993: M E Fortini; Ilaria Rebay; L A Caron; Spyros Artavanis-Tsakonas
An activated Notch receptor blocks cell-fate commitment in the developing Drosophila eye.
Nature 1993;365(6446):555-7.
1993: Ilaria Rebay; M E Fortini; Spyros Artavanis-Tsakonas
Analysis of phenotypic abnormalities and cell fate changes caused by dominant activated and dominant negative forms of the Notch receptor in Drosophila development.
Comptes rendus de l'Académie des sciences. Série III, Sciences de la vie 1993;316(9):1097-123.
1993: Ilaria Rebay; Richard G Fehon; Spyros Artavanis-Tsakonas
Specific truncations of Drosophila Notch define dominant activated and dominant negative forms of the receptor.
Cell 1993;74(2):319-29.
1993: M B Heintzelman; S A Frankel; Spyros Artavanis-Tsakonas; Mark S Mooseker
Cloning of a secretory gelsolin from Drosophila melanogaster.
Journal of molecular biology 1993;230(3):709-16.
1993: I A Dawson; S Roth; M Akam; Spyros Artavanis-Tsakonas
Mutations of the fizzy locus cause metaphase arrest in Drosophila melanogaster embryos.
Development (Cambridge, England) 1993;117(1):359-76.
1992: Stefano Stifani; CM Blaumueller; N J Redhead; R E Hill; Spyros Artavanis-Tsakonas
Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.
Nature genetics 1992;2(4):343.
1992: Stefano Stifani; CM Blaumueller; N J Redhead; R E Hill; Spyros Artavanis-Tsakonas
Human homologs of a Drosophila Enhancer of split gene product define a novel family of nuclear proteins.
Nature genetics 1992;2(2):119-27.
1992: J M Rothberg; Spyros Artavanis-Tsakonas
Modularity of the slit protein. Characterization of a conserved carboxy-terminal sequence in secreted proteins and a motif implicated in extracellular protein interactions.
Journal of molecular biology 1992;227(2):367-70.
1992: Christos Delidakis; Spyros Artavanis-Tsakonas
The Enhancer of split [E(spl)] locus of Drosophila encodes seven independent helix-loop-helix proteins.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(18):8731-5.
1992: Tian Xu; L A Caron; Richard G Fehon; Spyros Artavanis-Tsakonas
The involvement of the Notch locus in Drosophila oogenesis.
Development (Cambridge, England) 1992;115(4):913-22.
1991: Ilaria Rebay; Robert J Fleming; Richard G Fehon; Lucy Cherbas; P Cherbas; Spyros Artavanis-Tsakonas
Specific EGF repeats of Notch mediate interactions with Delta and Serrate: implications for Notch as a multifunctional receptor.
Cell 1991;67(4):687-99.
1991: Christos Delidakis; Anette Preiss; D A Hartley; Spyros Artavanis-Tsakonas
Two genetically and molecularly distinct functions involved in early neurogenesis reside within the Enhancer of split locus of Drosophila melanogaster.
Genetics 1991;129(3):803-23.
1991: Spyros Artavanis-Tsakonas; P Simpson
Choosing a cell fate: a view from the Notch locus.
Trends in genetics : TIG 1991;7(11-12):403-8.
1991: Richard G Fehon; K Johansen; Ilaria Rebay; Spyros Artavanis-Tsakonas
Complex cellular and subcellular regulation of notch expression during embryonic and imaginal development of Drosophila: implications for notch function.
The Journal of cell biology 1991;113(3):657-69.
1991: K Markopoulou; Spyros Artavanis-Tsakonas
Developmental analysis of the facets, a group of intronic mutations at the Notch locus of Drosophila melanogaster that affect postembryonic development.
The Journal of experimental zoology 1991;257(3):314-29.
1991: Spyros Artavanis-Tsakonas; Christos Delidakis; Richard G Fehon
The Notch locus and the cell biology of neuroblast segregation.
Annual review of cell biology 1991;7():427-52.
1990: J M Rothberg; J R Jacobs; C S Goodman; Spyros Artavanis-Tsakonas
slit: an extracellular protein necessary for development of midline glia and commissural axon pathways contains both EGF and LRR domains.
Genes & development 1990;4(12A):2169-87.
1990: Robert J Fleming; T N Scottgale; R J Diederich; Spyros Artavanis-Tsakonas
The gene Serrate encodes a putative EGF-like transmembrane protein essential for proper ectodermal development in Drosophila melanogaster.
Genes & development 1990;4(12A):2188-201.
1990: T Xu; Spyros Artavanis-Tsakonas
deltex, a locus interacting with the neurogenic genes, Notch, Delta and mastermind in Drosophila melanogaster.
Genetics 1990;126(3):665-77.
1990: Spyros Artavanis-Tsakonas; Christos Delidakis; Richard G Fehon; D Hartley; V Herndon; K Johansen; K Markopoulou; Anette Preiss; Ilaria Rebay; N Scottgale
Notch and the molecular genetics of neuroblast segregation in Drosophila.
Molecular reproduction and development 1990;27(1):23-7.
1990: Richard G Fehon; P J Kooh; Ilaria Rebay; C L Regan; Tian Xu; Marc A T Muskavitch; Spyros Artavanis-Tsakonas
Molecular interactions between the protein products of the neurogenic loci Notch and Delta, two EGF-homologous genes in Drosophila.
Cell 1990;61(3):523-34.
1990: Tian Xu; Ilaria Rebay; Robert J Fleming; T N Scottgale; Spyros Artavanis-Tsakonas
The Notch locus and the genetic circuitry involved in early Drosophila neurogenesis.
Genes & development 1990;4(3):464-75.
1989: K M Johansen; Richard G Fehon; Spyros Artavanis-Tsakonas
The notch gene product is a glycoprotein expressed on the cell surface of both epidermal and neuronal precursor cells during Drosophila development.
The Journal of cell biology 1989;109(5):2427-40.
1989: R G Ramos; B G Grimwade; K A Wharton; T N Scottgale; Spyros Artavanis-Tsakonas
Physical and functional definition of the Drosophila Notch locus by P element transformation.
Genetics 1989;123(2):337-48.
1989: K Markopoulou; Spyros Artavanis-Tsakonas
The expression of the neurogenic locus Notch during the postembryonic development of Drosophila melanogaster and its relationship to mitotic activity.
Journal of neurogenetics 1989;6(1):11-26.
1989: K Markopoulou; W J Welshons; Spyros Artavanis-Tsakonas
Phenotypic and molecular analysis of the facets, a group of intronic mutations at the Notch locus of Drosophila melanogaster which affect postembryonic development.
Genetics 1989;122(2):417-28.
1988: J M Rothberg; D A Hartley; Z Walther; Spyros Artavanis-Tsakonas
slit: an EGF-homologous locus of D. melanogaster involved in the development of the embryonic central nervous system.
Cell 1988;55(6):1047-59.
1988: D A Hartley; Anette Preiss; Spyros Artavanis-Tsakonas
A deduced gene product from the Drosophila neurogenic locus, enhancer of split, shows homology to mammalian G-protein beta subunit.
Cell 1988;55(5):785-95.
1988: Anette Preiss; D A Hartley; Spyros Artavanis-Tsakonas
The molecular genetics of Enhancer of split, a gene required for embryonic neural development in Drosophila.
The EMBO journal 1988;7(12):3917-27.
1987: D A Hartley; T A Xu; Spyros Artavanis-Tsakonas
The embryonic expression of the Notch locus of Drosophila melanogaster and the implications of point mutations in the extracellular EGF-like domain of the predicted protein.
The EMBO journal 1987;6(11):3407-17.
1985: K A Wharton; K M Johansen; T Xu; Spyros Artavanis-Tsakonas
Nucleotide sequence from the neurogenic locus notch implies a gene product that shares homology with proteins containing EGF-like repeats.
Cell 1985;43(3 Pt 2):567-81.
1985: B G Grimwade; Marc A T Muskavitch; W J Welshons; Barry Yedvobnick; Spyros Artavanis-Tsakonas
The molecular genetics of the Notch locus in Drosophila melanogaster.
Developmental biology 1985;107(2):503-19.
1985: K A Wharton; Barry Yedvobnick; V G Finnerty; Spyros Artavanis-Tsakonas
opa: a novel family of transcribed repeats shared by the Notch locus and other developmentally regulated loci in D. melanogaster.
Cell 1985;40(1):55-62.
1983: Spyros Artavanis-Tsakonas; Marc A T Muskavitch; Barry Yedvobnick
Molecular cloning of Notch, a locus affecting neurogenesis in Drosophila melanogaster.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(7):1977-81.