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Venkatesh Handratta

Research Profile

Living Beings

Disorders

Chemicals & Drugs

Anatomy

Tumor Cell Line

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Drug Dose Response Relationship

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Publications

TOP 3
Jyoti B Patel; Aakanksha Khandelwal; Pankaj Chopra; Venkatesh D Handratta; Vincent Njar
Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents.
Zhiyong Guo; Bojie Dai; Tianyun Jiang; Kexin Xu; Yingqiu Xie; Oekyung Kim; Issa Nesheiwat; Xiangtian Kong; Jonathan Melamed; Venkatesh D Handratta; Vincent Njar; Angela Brodie; Li-Rong Yu; Timothy D Veenstra; Hegang Chen; Yun Qiu
Regulation of androgen receptor activity by tyrosine phosphorylation.
Danijela Jelovac; Luciana Macedo; Olga Goloubeva; Venkatesh D Handratta; Angela Brodie
Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model.

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All Publications

2007: Jyoti B Patel; Aakanksha Khandelwal; Pankaj Chopra; Venkatesh D Handratta; Vincent Njar
Murine toxicology and pharmacokinetics of novel retinoic acid metabolism blocking agents.
Cancer chemotherapy and pharmacology 2007;60(6):899-905.
2006: Zhiyong Guo; Bojie Dai; Tianyun Jiang; Kexin Xu; Yingqiu Xie; Oekyung Kim; Issa Nesheiwat; Xiangtian Kong; Jonathan Melamed; Venkatesh D Handratta; Vincent Njar; Angela Brodie; Li-Rong Yu; Timothy D Veenstra; Hegang Chen; Yun Qiu
Regulation of androgen receptor activity by tyrosine phosphorylation.
Cancer cell 2006;10(4):309-19.
2005: Danijela Jelovac; Luciana Macedo; Olga Goloubeva; Venkatesh D Handratta; Angela Brodie
Additive antitumor effect of aromatase inhibitor letrozole and antiestrogen fulvestrant in a postmenopausal breast cancer model.
Cancer research 2005;65(12):5439-44.
2005: Venkatesh D Handratta; Tadas S Vasaitis; Vincent Njar; Lalji Gediya; Ritesh Kataria; Pankaj Chopra; Donnell Newman; Rena Farquhar; Zhiyong Guo; Yun Qiu; Angela Brodie
Novel C-17-heteroaryl steroidal CYP17 inhibitors/antiandrogens: synthesis, in vitro biological activity, pharmacokinetics, and antitumor activity in the LAPC4 human prostate cancer xenograft model.
Journal of medicinal chemistry 2005;48(8):2972-84.
2004: Jyoti B Patel; Carlic K Huynh; Venkatesh D Handratta; Lalji Gediya; Angela Brodie; Olga Goloubeva; Omoshile O Clement; Ivo P Nanne; Dianne Robert Soprano; Vincent Njar
Novel retinoic acid metabolism blocking agents endowed with multiple biological activities are efficient growth inhibitors of human breast and prostate cancer cells in vitro and a human breast tumor xenograft in nude mice.
Journal of medicinal chemistry 2004;47(27):6716-29.
2004: Danijela Jelovac; Luciana Macedo; Venkatesh D Handratta; Brian Long; Olga Goloubeva; James N Ingle; Angela Brodie
Effects of exemestane and tamoxifen in a postmenopausal breast cancer model.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(21):7375-81.
2004: Venkatesh D Handratta; Danijela Jelovac; Brian Long; Ritesh Kataria; Ivo P Nnane; Vincent Njar; Angela Brodie
Potent CYP17 inhibitors: improved syntheses, pharmacokinetics and anti-tumor activity in the LNCaP human prostate cancer model.
The Journal of steroid biochemistry and molecular biology 2004;92(3):155-65.
2004: Brian Long; Danijela Jelovac; Venkatesh D Handratta; Apinya Thiantanawat; Nicol MacPherson; Joseph Ragaz; Olga Goloubeva; Angela Brodie
Therapeutic strategies using the aromatase inhibitor letrozole and tamoxifen in a breast cancer model.
Journal of the National Cancer Institute 2004;96(6):456-65.
2003: Na Zhu; Yangzhi Ling; Xiaoping Lei; Venkatesh D Handratta; Angela Brodie
Novel P450(17alpha) inhibitors: 17-(2'-oxazolyl)- and 17-(2'-thiazolyl)-androstene derivatives.
Steroids 2003;68(7-8):603-11.
2003: Omoshile O Clement; Clive M Freeman; Rolf W Hartmann; Venkatesh D Handratta; Tadas S Vasaitis; Angela Brodie; Vincent Njar
Three dimensional pharmacophore modeling of human CYP17 inhibitors. Potential agents for prostate cancer therapy.
Journal of medicinal chemistry 2003;46(12):2345-51.

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