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Hans Hansen

Research Profile

Chemicals & Drugs

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Serengulam V Govindan; Thomas M Cardillo; Sung-Ju Moon; Hans J Hansen; David M Goldenberg
CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates.
David M Goldenberg; Edmund A Rossi; Rhona Stein; Thomas M Cardillo; Myron S Czuczman; Francisco J Hernandez-Ilizaliturri; Hans J Hansen; Chien-Hsing Chang
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody.
Sung-Ju Moon; Serengulam V Govindan; Thomas M Cardillo; Christopher A D'Souza; Hans J Hansen; David M Goldenberg
Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy.

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All Publications

2009: Serengulam V Govindan; Thomas M Cardillo; Sung-Ju Moon; Hans J Hansen; David M Goldenberg
CEACAM5-targeted therapy of human colonic and pancreatic cancer xenografts with potent labetuzumab-SN-38 immunoconjugates.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(19):6052-61.
2009: David M Goldenberg; Edmund A Rossi; Rhona Stein; Thomas M Cardillo; Myron S Czuczman; Francisco J Hernandez-Ilizaliturri; Hans J Hansen; Chien-Hsing Chang
Properties and structure-function relationships of veltuzumab (hA20), a humanized anti-CD20 monoclonal antibody.
Blood 2009;113(5):1062-70.
2008: Sung-Ju Moon; Serengulam V Govindan; Thomas M Cardillo; Christopher A D'Souza; Hans J Hansen; David M Goldenberg
Antibody conjugates of 7-ethyl-10-hydroxycamptothecin (SN-38) for targeted cancer chemotherapy.
Journal of medicinal chemistry 2008;51(21):6916-26.
2007: Rhona Stein; M Jules Mattes; Thomas M Cardillo; Hans J Hansen; Chien-Hsing Chang; Jack Burton; Serengulam V Govindan; David M Goldenberg
CD74: a new candidate target for the immunotherapy of B-cell neoplasms.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(18 Pt 2):5556s-5563s.
2007: Josette Carnahan; Rhona Stein; Zhengxing Qu; Kristen Hess; Alessandra Cesano; Hans J Hansen; David M Goldenberg
Epratuzumab, a CD22-targeting recombinant humanized antibody with a different mode of action from rituximab.
Molecular immunology 2007;44(6):1331-41.
2007: Rosalyn D Blumenthal; Evelyn Leon; Hans J Hansen; David M Goldenberg
Expression patterns of CEACAM5 and CEACAM6 in primary and metastatic cancers.
BMC cancer 2007;7():2.
2006: Rhona Stein; Zhengxing Qu; Susan Chen; David Solis; Hans J Hansen; David M Goldenberg
Characterization of a humanized IgG4 anti-HLA-DR monoclonal antibody that lacks effector cell functions but retains direct antilymphoma activity and increases the potency of rituximab.
Blood 2006;108(8):2736-44.
2005: Chien-Hsing Chang; Puja Sapra; Sailaja S Vanama; Hans J Hansen; Ivan D Horak; David M Goldenberg
Effective therapy of human lymphoma xenografts with a novel recombinant ribonuclease/anti-CD74 humanized IgG4 antibody immunotoxin.
Blood 2005;106(13):4308-14.
2005: Robert M Sharkey; Thomas M Cardillo; Edmund A Rossi; Chien-Hsing Chang; Habibe Karacay; William J McBride; Hans J Hansen; Ivan D Horak; David M Goldenberg
Signal amplification in molecular imaging by pretargeting a multivalent, bispecific antibody.
Nature medicine 2005;11(11):1250-5.
2005: Rosalyn D Blumenthal; Hans J Hansen; David M Goldenberg
Inhibition of adhesion, invasion, and metastasis by antibodies targeting CEACAM6 (NCA-90) and CEACAM5 (Carcinoembryonic Antigen).
Cancer research 2005;65(19):8809-17.
2005: Edmund A Rossi; Chien-Hsing Chang; Michele J Losman; Robert M Sharkey; Habibe Karacay; William McBride; Thomas M Cardillo; Hans J Hansen; Zhengxing Qu; Ivan D Horak; David M Goldenberg
Pretargeting of carcinoembryonic antigen-expressing cancers with a trivalent bispecific fusion protein produced in myeloma cells.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(19 Pt 2):7122s-7129s.
2005: Serengulam V Govindan; Gary L Griffiths; Hans J Hansen; Ivan D Horak; David M Goldenberg
Cancer therapy with radiolabeled and drug/toxin-conjugated antibodies.
Technology in cancer research & treatment 2005;4(4):375-91.
2005: Puja Sapra; Rhona Stein; Jennifer Pickett; Zhengxing Qu; Serengulam V Govindan; Thomas M Cardillo; Hans J Hansen; Ivan D Horak; Gary L Griffiths; David M Goldenberg
Anti-CD74 antibody-doxorubicin conjugate, IMMU-110, in a human multiple myeloma xenograft and in monkeys.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(14):5257-64.
2005: Zhengxing Qu; Gary L Griffiths; William A Wegener; Chien-Hsing Chang; Serengulam V Govindan; Ivan D Horak; Hans J Hansen; David M Goldenberg
Development of humanized antibodies as cancer therapeutics.
Methods (San Diego, Calif.) 2005;36(1):84-95.
2005: Rhona Stein; Serengulam V Govindan; Marianne Hayes; Gary L Griffiths; Hans J Hansen; Ivan D Horak; David M Goldenberg
Advantage of a residualizing iodine radiolabel in the therapy of a colon cancer xenograft targeted with an anticarcinoembryonic antigen monoclonal antibody.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(7):2727-34.
2005: Rosalyn D Blumenthal; Louis Osorio; Marianne K Hayes; Ivan D Horak; Hans J Hansen; David M Goldenberg
Carcinoembryonic antigen antibody inhibits lung metastasis and augments chemotherapy in a human colonic carcinoma xenograft.
Cancer immunology, immunotherapy : CII 2005;54(4):315-27.
2005: Serengulam V Govindan; Gary L Griffiths; Rhona Stein; Philip Andrews; Robert M Sharkey; Hans J Hansen; Ivan D Horak; David M Goldenberg
Clinical-scale radiolabeling of a humanized anticarcinoembryonic antigen monoclonal antibody, hMN-14, with residualizing 131I for use in radioimmunotherapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2005;46(1):153-9.
2004: Rhona Stein; Zhengxing Qu; Thomas M Cardillo; Susan Chen; Adriane Rosario; Ivan D Horak; Hans J Hansen; David M Goldenberg
Antiproliferative activity of a humanized anti-CD74 monoclonal antibody, hLL1, on B-cell malignancies.
Blood 2004;104(12):3705-11.
2004: John P Leonard; Morton Coleman; Jamie C Ketas; Amy Chadburn; Richard R Furman; Michael W Schuster; Eric J Feldman; Michelle Ashe; Stephen J Schuster; William A Wegener; Hans J Hansen; Heather Ziccardi; Michael Eschenberg; Urte Gayko; Scott Z Fields; Alessandra Cesano; David M Goldenberg
Epratuzumab, a humanized anti-CD22 antibody, in aggressive non-Hodgkin's lymphoma: phase I/II clinical trial results.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(16):5327-34.
2004: Rhona Stein; Zhengxing Qu; Susan Chen; Adriane Rosario; Victoria Shi; Marianne Hayes; Ivan D Horak; Hans J Hansen; David M Goldenberg
Characterization of a new humanized anti-CD20 monoclonal antibody, IMMU-106, and Its use in combination with the humanized anti-CD22 antibody, epratuzumab, for the therapy of non-Hodgkin's lymphoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(8):2868-78.
2004: Serengulam V Govindan; Rhona Stein; Zhengxing Qu; Susan Chen; Philip Andrews; Hong Ma; Hans J Hansen; Gary L Griffiths; Ivan D Horak; David M Goldenberg
Preclinical therapy of breast cancer with a radioiodinated humanized anti-EGP-1 monoclonal antibody: advantage of a residualizing iodine radiolabel.
Breast cancer research and treatment 2004;84(2):173-82.
2004: Gary L Griffiths; Chien-Hsing Chang; William J McBride; Edmund A Rossi; Agatha Sheerin; German R Tejada; Habibe Karacay; Robert M Sharkey; Ivan D Horak; Hans J Hansen; David M Goldenberg
Reagents and methods for PET using bispecific antibody pretargeting and 68Ga-radiolabeled bivalent hapten-peptide-chelate conjugates.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2004;45(1):30-9.
2003: Gary L Griffiths; M Jules Mattes; Rhona Stein; Serengulam V Govindan; Ivan D Horak; Hans J Hansen; David M Goldenberg
Cure of SCID mice bearing human B-lymphoma xenografts by an anti-CD74 antibody-anthracycline drug conjugate.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(17):6567-71.
2003: Robert M Sharkey; Habibe Karacay; Heidi Richel; William J McBride; Edmund A Rossi; Ken Chang; Dion Yeldell; Gary L Griffiths; Hans J Hansen; David M Goldenberg
Optimizing bispecific antibody pretargeting for use in radioimmunotherapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 2):3897S-913S.
2003: Edmund A Rossi; Robert M Sharkey; William McBride; Habibe Karacay; Li Zeng; Hans J Hansen; David M Goldenberg; Chien-Hsing Chang
Development of new multivalent-bispecific agents for pretargeting tumor localization and therapy.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(10 Pt 2):3886S-96S.
2003: John P Leonard; Morton Coleman; Jamie C Ketas; Amy Chadburn; Scott Ely; Richard R Furman; William A Wegener; Hans J Hansen; Heather Ziccardi; Michael Eschenberg; Urte Gayko; Alessandra Cesano; David M Goldenberg
Phase I/II trial of epratuzumab (humanized anti-CD22 antibody) in indolent non-Hodgkin's lymphoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2003;21(16):3051-9.
2003: David M Goldenberg; Chien-Hsing Chang; Robert M Sharkey; Edmund A Rossi; Habibe Karacay; William McBride; Hans J Hansen; Jean-François Chatal; Jacques Barbet
Radioimmunotherapy: is avidin-biotin pretargeting the preferred choice among pretargeting methods?
European journal of nuclear medicine and molecular imaging 2003;30(5):777-80.
2003: Robert M Sharkey; William J McBride; Habibe Karacay; Ken Chang; Gary L Griffiths; Hans J Hansen; David M Goldenberg
A universal pretargeting system for cancer detection and therapy using bispecific antibody.
Cancer research 2003;63(2):354-63.
2003: Rhona Stein; Serengulam V Govindan; M Jules Mattes; Susan Chen; Linda Reed; Guy Newsome; Bill J McBride; Gary L Griffiths; Hans J Hansen; David M Goldenberg
Improved iodine radiolabels for monoclonal antibody therapy.
Cancer research 2003;63(1):111-8.
2002: Habibe Karacay; Robert M Sharkey; William J McBride; Gary L Griffiths; Z Qu; Ken Chang; Hans J Hansen; David M Goldenberg
Pretargeting for cancer radioimmunotherapy with bispecific antibodies: role of the bispecific antibody's valency for the tumor target antigen.
Bioconjugate chemistry 2002;13(5):1054-70.
2002: Chien-Hsing Chang; Robert M Sharkey; Edmund A Rossi; Habibe Karacay; William McBride; Hans J Hansen; Jean-François Chatal; Jacques Barbet; David M Goldenberg
Molecular advances in pretargeting radioimunotherapy with bispecific antibodies.
Molecular cancer therapeutics 2002;1(7):553-63.
2001: Rhona Stein; Serengulam V Govindan; Susan Chen; Linda Reed; H Spiegelman; Gary L Griffiths; Hans J Hansen; David M Goldenberg
Successful therapy of a human lung cancer xenograft using MAb RS7 labeled with residualizing radioiodine.
Critical reviews in oncology/hematology 2001;39(1-2):173-80.
2001: Rhona Stein; Serengulam V Govindan; Susan Chen; Linda Reed; Heidi Richel; Gary L Griffiths; Hans J Hansen; David M Goldenberg
Radioimmunotherapy of a human lung cancer xenograft with monoclonal antibody RS7: evaluation of (177)Lu and comparison of its efficacy with that of (90)Y and residualizing (131)I.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2001;42(6):967-74.
2000: Habibe Karacay; William J McBride; Gary L Griffiths; Robert M Sharkey; Jacques Barbet; Hans J Hansen; David M Goldenberg
Experimental pretargeting studies of cancer with a humanized anti-CEA x murine anti-[In-DTPA] bispecific antibody construct and a (99m)Tc-/(188)Re-labeled peptide.
Bioconjugate chemistry 2000;11(6):842-54.
1999: SO Leung; Zhengxing Qu; Hans J Hansen; LB Shih; J Wang; Michele J Losman; David M Goldenberg; Robert M Sharkey
The effects of domain deletion, glycosylation, and long IgG3 hinge on the biodistribution and serum stability properties of a humanized IgG1 immunoglobulin, hLL2, and its fragments.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3106s-3117s.
1999: Michele J Losman; Zhengxing Qu; IS Krishnan; J Wang; Hans J Hansen; David M Goldenberg; SO Leung
Generation and monitoring of cell lines producing humanized antibodies.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3101s-3105s.
1999: Zhengxing Qu; Michele J Losman; K C Eliassen; Hans J Hansen; David M Goldenberg; SO Leung
Humanization of Immu31, an alpha-fetoprotein-specific antibody.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3095s-3100s.
1999: Rhona Stein; Serengulam V Govindan; M Jules Mattes; LB Shih; Gary L Griffiths; Hans J Hansen; David M Goldenberg
Targeting human cancer xenografts with monoclonal antibodies labeled using radioiodinated, diethylenetriaminepentaacetic acid-appended peptides.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3079s-3087s.
1999: Gary L Griffiths; David M Goldenberg; F Roesch; Hans J Hansen
Radiolabeling of an anti-carcinoembryonic antigen antibody Fab' fragment (CEA-Scan) with the positron-emitting radionuclide Tc-94m.
Clinical cancer research : an official journal of the American Association for Cancer Research 1999;5(10 Suppl):3001s-3003s.
1999: IS Krishnan; Hans J Hansen; D V Gold; David M Goldenberg; SO Leung
Co-secretion of two distinct kappa light chains by the mu-9 hybridoma.
Hybridoma 1999;18(4):325-33.
1999: Serengulam V Govindan; M Jules Mattes; R Stein; B J McBride; Habibe Karacay; David M Goldenberg; Hans J Hansen; Gary L Griffiths
Labeling of monoclonal antibodies with diethylenetriaminepentaacetic acid-appended radioiodinated peptides containing D-amino acids.
Bioconjugate chemistry 1999;10(2):231-40.
1998: Serengulam V Govindan; LB Shih; David M Goldenberg; Robert M Sharkey; Habibe Karacay; J E Donnelly; Michele J Losman; Hans J Hansen; Gary L Griffiths
90Yttrium-labeled complementarity-determining-region-grafted monoclonal antibodies for radioimmunotherapy: radiolabeling and animal biodistribution studies.
Bioconjugate chemistry 1998;9(6):773-82.
1998: Habibe Karacay; GL Ong; Hans J Hansen; Gary L Griffiths; D M Goldenberg; M Jules Mattes
Intracellular processing of 99Tcm-antibody conjugates.
Nuclear medicine communications 1998;19(10):971-9.
1998: Zhengxing Qu; Robert M Sharkey; Hans J Hansen; LB Shih; Serengulam V Govindan; J Shen; David M Goldenberg; SO Leung
Carbohydrates engineered at antibody constant domains can be used for site-specific conjugation of drugs and chelates.
Journal of immunological methods 1998;213(2):131-44.
1997: IS Krishnan; Hans J Hansen; Michele J Losman; David M Goldenberg; SO Leung
Chimerization of Mu-9: a colon-specific antigen-p antibody reactive with gastrointestinal carcinomas.
Cancer 1997;80(12 Suppl):2667-74.
1997: Michele J Losman; Hans J Hansen; H Dworak; IS Krishnan; Zhengxing Qu; LB Shih; L Zeng; David M Goldenberg; SO Leung
Generation of a high-producing clone of a humanized anti-B-cell lymphoma monoclonal antibody (hLL2).
Cancer 1997;80(12 Suppl):2660-6.
1997: Robert M Sharkey; Habibe Karacay; Gary L Griffiths; Thomas M Behr; Rosalyn D Blumenthal; M Jules Mattes; Hans J Hansen; David M Goldenberg
Development of a streptavidin-anti-carcinoembryonic antigen antibody, radiolabeled biotin pretargeting method for radioimmunotherapy of colorectal cancer. Studies in a human colon cancer xenograft model.
Bioconjugate chemistry 1997;8(4):595-604.
1997: Habibe Karacay; Robert M Sharkey; Serengulam V Govindan; William J McBride; David M Goldenberg; Hans J Hansen; Gary L Griffiths
Development of a streptavidin-anti-carcinoembryonic antigen antibody, radiolabeled biotin pretargeting method for radioimmunotherapy of colorectal cancer. Reagent development.
Bioconjugate chemistry 1997;8(4):585-94.
1997: Robert M Sharkey; Thomas M Behr; M Jules Mattes; Rhona Stein; Gary L Griffiths; LB Shih; Hans J Hansen; Rosalyn D Blumenthal; RM Dunn; ME Juweid; David M Goldenberg
Advantage of residualizing radiolabels for an internalizing antibody against the B-cell lymphoma antigen, CD22.
Cancer immunology, immunotherapy : CII 1997;44(3):179-88.
1997: ME Juweid; RM Dunn; Robert M Sharkey; AD Rubin; Hans J Hansen; David M Goldenberg
99Tcm-LL1: a potential new bone marrow imaging agent.
Nuclear medicine communications 1997;18(2):142-8.
1996: Hans J Hansen; GL Ong; H Diril; A Valdez; P A Roche; Gary L Griffiths; David M Goldenberg; M Jules Mattes
Internalization and catabolism of radiolabelled antibodies to the MHC class-II invariant chain by B-cell lymphomas.
The Biochemical journal 1996;320 ( Pt 1)():293-300.
1996: ME Juweid; Robert M Sharkey; T M Behr; LC Swayne; R Dunn; Zhiliang Ying; Jeffry A Siegel; Hans J Hansen; David M Goldenberg
Clinical evaluation of tumor targeting with the anticarcinoembryonic antigen murine monoclonal antibody fragment, MN-14 F(ab)2.
Cancer 1996;78(1):157-68.
1996: Serengulam V Govindan; David M Goldenberg; R C Grebenau; Hans J Hansen; Gary L Griffiths
Thiolations, 99mTc labelings, and animal in vivo biodistributions of divalent monoclonal antibody fragments.
Bioconjugate chemistry 1996;7(3):290-7.
1995: SO Leung; David M Goldenberg; A S Dion; M C Pellegrini; J Shevitz; LB Shih; Hans J Hansen
Construction and characterization of a humanized, internalizing, B-cell (CD22)-specific, leukemia/lymphoma antibody, LL2.
Molecular immunology 1995;32(17-18):1413-27.
1995: Michele J Losman; SO Leung; LB Shih; J Shevitz; R Shukla; L Haraga; David M Goldenberg; Hans J Hansen
Development and evaluation of the specificity of a rat monoclonal anti-idiotype antibody, WN, to an anti-B-cell lymphoma monoclonal antibody, LL2.
Cancer research 1995;55(23 Suppl):5978s-5982s.
1995: SO Leung; Habibe Karacay; Michele J Losman; Gary L Griffiths; David M Goldenberg; Hans J Hansen
Bacterial expression of a kemptide fusion protein facilitates 32P labeling of a humanized, anti-carcinoembryonic antigen (hMN-14) antibody fragment.
Cancer research 1995;55(23 Suppl):5968s-5972s.
1995: ME Juweid; Robert M Sharkey; A Markowitz; T Behr; LC Swayne; R Dunn; Hans J Hansen; J Shevitz; SO Leung; AD Rubin
Treatment of non-Hodgkin's lymphoma with radiolabeled murine, chimeric, or humanized LL2, an anti-CD22 monoclonal antibody.
Cancer research 1995;55(23 Suppl):5899s-5907s.
1995: Serengulam V Govindan; David M Goldenberg; Gary L Griffiths; SO Leung; Michele J Losman; Hans J Hansen
Site-specific modifications of light chain glycosylated antilymphoma (LL2) and anti-carcinoembryonic antigen (hImmu-14-N) antibody divalent f1agments.
Cancer research 1995;55(23 Suppl):5721s-5725s.
1995: S Leung; Michele J Losman; Serengulam V Govindan; Gary L Griffiths; David M Goldenberg; Hans J Hansen
Engineering a unique glycosylation site for site-specific conjugation of haptens to antibody fragments.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(11):5919-26.
1995: SO Leung; A S Dion; M C Pellegrini; Michele J Losman; R C Grebenau; David M Goldenberg; Hans J Hansen
Effect of VK framework-1 glycosylation on the binding affinity of lymphoma-specific murine and chimeric LL2 antibodies and its potential use as a novel conjugation site.
International journal of cancer. Journal international du cancer 1995;60(4):534-8.
1994: SO Leung; J Shevitz; M C Pellegrini; A S Dion; LB Shih; David M Goldenberg; Hans J Hansen
Chimerization of LL2, a rapidly internalizing antibody specific for B cell lymphoma.
Hybridoma 1994;13(6):469-76.
1994: Gary L Griffiths; David M Goldenberg; A L Jones; Hans J Hansen
Preparation of a pure 99mTc-F(ab')2 radioimmunoconjugate by direct labeling methods.
Nuclear medicine and biology 1994;21(4):649-55.
1994: LB Shih; Suzanne R Thorpe; Gary L Griffiths; H Diril; GL Ong; Hans J Hansen; David M Goldenberg; M Jules Mattes
The processing and fate of antibodies and their radiolabels bound to the surface of tumor cells in vitro: a comparison of nine radiolabels.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1994;35(5):899-908.
1994: Gary L Griffiths; David M Goldenberg; H Diril; Hans J Hansen
Technetium-99m, rhenium-186, and rhenium-188 direct-labeled antibodies.
Cancer 1994;73(3 Suppl):761-8.
1993: Rhona Stein; E Belisle; Hans J Hansen; David M Goldenberg
Epitope specificity of the anti-(B cell lymphoma) monoclonal antibody, LL2.
Cancer immunology, immunotherapy : CII 1993;37(5):293-8.
1993: SO Leung; A S Dion; M C Pellegrini; David M Goldenberg; Hans J Hansen
An extended primer set for PCR amplification of murine kappa variable regions.
BioTechniques 1993;15(2):286-92.
1993: Hans J Hansen; David M Goldenberg; E S Newman; R Grebenau; Robert M Sharkey
Characterization of second-generation monoclonal antibodies against carcinoembryonic antigen.
Cancer 1993;71(11):3478-85.
1992: R C Grebenau; David M Goldenberg; C H Chang; G A Koch; D V Gold; A Kunz; Hans J Hansen
Microheterogeneity of a purified IgG1 due to asymmetric Fab glycosylation.
Molecular immunology 1992;29(6):751-8.
1992: S Murthy; Robert M Sharkey; David M Goldenberg; R E Lee; C M Pinsky; Hans J Hansen; K Burger; L C Swayne
Lymphoma imaging with a new technetium-99m labelled antibody, LL2.
European journal of nuclear medicine 1992;19(6):394-401.
1991: M J Losman; Hans J Hansen; Robert M Sharkey; David M Goldenberg; Marc Monestier
Human response against NP-4, a mouse antibody to carcinoembryonic antigen: human anti-idiotype antibodies mimic an epitope on the tumor antigen.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(8):3421-5.
1990: M J Losman; Marc Monestier; Hans J Hansen; David M Goldenberg
Baboon anti-idiotype antibodies mimic a carcinoembryonic antigen epitope.
International journal of cancer. Journal international du cancer 1990;46(2):310-4.
1990: Robert M Sharkey; David M Goldenberg; H Goldenberg; R E Lee; C Ballance; D Pawlyk; D Varga; Hans J Hansen
Murine monoclonal antibodies against carcinoembryonic antigen: immunological, pharmacokinetic, and targeting properties in humans.
Cancer research 1990;50(9):2823-31.
1990: Robert M Sharkey; Rosalyn D Blumenthal; Hans J Hansen; David M Goldenberg
Biological considerations for radioimmunotherapy.
Cancer research 1990;50(3 Suppl):964s-969s.
1990: Robert M Sharkey; David V Gold; R Aninipot; R Vagg; C Ballance; E S Newman; F Ostella; Hans J Hansen; David M Goldenberg
Comparison of tumor targeting in nude mice by murine monoclonal antibodies directed against different human colorectal cancer antigens.
Cancer research 1990;50(3 Suppl):828s-834s.
1990: Hans J Hansen; A L Jones; Robert M Sharkey; R Grebenau; N Blazejewski; A Kunz; M J Buckley; E S Newman; F Ostella; David M Goldenberg
Preclinical evaluation of an "instant" 99mTc-labeling kit for antibody imaging.
Cancer research 1990;50(3 Suppl):794s-798s.
1990: David M Goldenberg; H Goldenberg; R M Sharkey; R E Lee; J A Horowitz; T C Hall; Hans J Hansen
In-vivo antibody imaging for the detection of human tumors.
Cancer treatment and research 1990;51():273-92.
1990: Hans J Hansen; A L Jones; R Grebenau; A Kunz; David M Goldenberg
Labeling of anti-tumor antibodies and antibody fragments with Tc-99m.
Cancer treatment and research 1990;51():233-44.
1989: David M Goldenberg; H Goldenberg; Robert M Sharkey; R E Lee; E Higgenbotham-Ford; J A Horowitz; T C Hall; C M Pinsky; Hans J Hansen
Imaging of colorectal carcinoma with radiolabeled antibodies.
Seminars in nuclear medicine 1989;19(4):262-81.
1989: E S Newman; L A Moskie; R N Duggal; David M Goldenberg; Hans J Hansen
Murine monoclonal antibody adsorbed onto vinylidene fluoride floccules used to eliminate antibody interference in "sandwich"-type immunoassays.
Clinical chemistry 1989;35(8):1743-6.
1989: Hans J Hansen; G LaFontaine; E S Newman; Morton K Schwartz; A Malkin; K Mojzisik; E W Martin; David M Goldenberg
Solving the problem of antibody interference in commercial "sandwich"-type immunoassays of carcinoembryonic antigen.
Clinical chemistry 1989;35(1):146-51.
1988: Rosalyn D Blumenthal; Robert M Sharkey; D J Snyder; Hans J Hansen; David M Goldenberg
Reduction of radioantibody-induced myelotoxicity in hamsters by recombinant interleukin-1.
Cancer research 1988;48(19):5403-6.
1988: F J Primus; E A Kelley; Hans J Hansen; David M Goldenberg
"Sandwich"-type immunoassay of carcinoembryonic antigen in patients receiving murine monoclonal antibodies for diagnosis and therapy.
Clinical chemistry 1988;34(2):261-4.

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