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Torben Hansen

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Grunnet Louise G; Nilsson Emma; Ling Charlotte; Hansen Torben; Pedersen Oluf; Groop Leif; Vaag Allan; Poulsen Pernille
Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.
Boesgaard T W; Nielsen T T; Josefsen K; Hansen T; Jørgensen T; Pedersen O; Nørremølle A; Nielsen J E; Hasholt L
Huntington's disease does not appear to increase the risk of diabetes mellitus.
Reiling Erwin; van Vliet-Ostaptchouk Jana V; van 't Riet Esther; van Haeften Timon W; Arp Pascal A; Hansen Torben; Kremer Dennis; Groenewoud Marlous J; van Hove Els C; Romijn Johannes A; Smit Jan W A; Nijpels Giel; Heine Robert J; Uitterlinden André G; Pedersen Oluf; Slagboom P Eline; Maassen Johannes A; Hofker Marten H; 't Hart Leen M; Dekker Jacqueline M
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.

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All Publications

2009: Grunnet Louise G; Nilsson Emma; Ling Charlotte; Hansen Torben; Pedersen Oluf; Groop Leif; Vaag Allan; Poulsen Pernille
Regulation and function of FTO mRNA expression in human skeletal muscle and subcutaneous adipose tissue.
Diabetes 2009;58(10):2402-8.
2009: Boesgaard T W; Nielsen T T; Josefsen K; Hansen T; Jørgensen T; Pedersen O; Nørremølle A; Nielsen J E; Hasholt L
Huntington's disease does not appear to increase the risk of diabetes mellitus.
Journal of neuroendocrinology 2009;21(9):770-6.
2009: Reiling Erwin; van Vliet-Ostaptchouk Jana V; van 't Riet Esther; van Haeften Timon W; Arp Pascal A; Hansen Torben; Kremer Dennis; Groenewoud Marlous J; van Hove Els C; Romijn Johannes A; Smit Jan W A; Nijpels Giel; Heine Robert J; Uitterlinden André G; Pedersen Oluf; Slagboom P Eline; Maassen Johannes A; Hofker Marten H; 't Hart Leen M; Dekker Jacqueline M
Genetic association analysis of 13 nuclear-encoded mitochondrial candidate genes with type II diabetes mellitus: the DAMAGE study.
European journal of human genetics : EJHG 2009;17(8):1056-62.
2009: Clausen Tine D; Mathiesen Elisabeth R; Hansen Torben; Pedersen Oluf; Jensen Dorte M; Lauenborg Jeannet; Schmidt Lone; Damm Peter
Overweight and the metabolic syndrome in adult offspring of women with diet-treated gestational diabetes mellitus or type 1 diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(7):2464-70.
2009: Sparsø T; Grarup N; Andreasen C; Albrechtsen A; Holmkvist J; Andersen G; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Madsbad S; Hansen T; Pedersen O
Combined analysis of 19 common validated type 2 diabetes susceptibility gene variants shows moderate discriminative value and no evidence of gene-gene interaction.
Diabetologia 2009;52(7):1308-14.
2009: Pilgaard K; Jensen C B; Schou J H; Lyssenko V; Wegner L; Brøns C; Vilsbøll T; Hansen T; Madsbad S; Holst J J; Vølund A; Poulsen P; Groop L; Pedersen O; Vaag A A
The T allele of rs7903146 TCF7L2 is associated with impaired insulinotropic action of incretin hormones, reduced 24 h profiles of plasma insulin and glucagon, and increased hepatic glucose production in young healthy men.
Diabetologia 2009;52(7):1298-307.
2009: Lauridsen Mette Høj; Boesgaard Trine Welløv; Pedersen Oluf Borbye; Hansen Torben; Hertz Birgitte
[Diabetes in infants may be treated with sulfonylurea as a replacement for insulin]
Ugeskrift for laeger 2009;171(23):1923-4.
2009: Sparsø Thomas; Bonnefond Amélie; Andersson Ehm; Bouatia-Naji Nabila; Holmkvist Johan; Wegner Lise; Grarup Niels; Gjesing Anette P; Banasik Karina; Cavalcanti-Proença Christine; Marchand Marion; Vaxillaire Martine; Charpentier Guillaume; Jarvelin Marjo-Riitta; Tichet Jean; Balkau Beverley; Marre Michel; Lévy-Marchal Claire; Faerch Kristine; Borch-Johnsen Knut; Jørgensen Torben; Madsbad Sten; Poulsen Pernille; Vaag Allan; Dina Christian; Hansen Torben; Pedersen Oluf; Froguel Philippe
G-allele of intronic rs10830963 in MTNR1B confers increased risk of impaired fasting glycemia and type 2 diabetes through an impaired glucose-stimulated insulin release: studies involving 19,605 Europeans.
Diabetes 2009;58(6):1450-6.
2009: Hansen Thomas V O; Ejlertsen Bent; Albrechtsen Anders; Bergsten Eva; Bjerregaard Peter; Hansen Torben; Myrhøj Torben; Nielsen Peter B; Timmermans-Wielenga Vera; Andersen Mette K; Jønson Lars; Nielsen Finn C
A common Greenlandic Inuit BRCA1 RING domain founder mutation.
Breast cancer research and treatment 2009;115(1):69-76.
2009: Zobel Dorit P; Andreasen Camilla H; Burgdorf Kristoffer S; Andersson Ehm A; Sandbaek Annelli; Lauritzen Torsten; Borch-Johnsen Knut; Jørgensen Torben; Maeda Shiro; Nakamura Yusuke; Eiberg Hans; Pederse Oluf; Hansen Torben
Variation in the gene encoding Krüppel-like factor 7 influences body fat: studies of 14 818 Danes.
European journal of endocrinology / European Federation of Endocrine Societies 2009;160(4):603-9.
2009: Gylvin T; Ek J; Nolsøe R; Albrechtsen A; Andersen G; Bergholdt R; Brorsson C; Bang-Berthelsen C H; Hansen T; Karlsen A E; Billestrup N; Borch-Johnsen K; Jørgensen T; Pedersen O; Mandrup-Poulsen T; Nerup J; Pociot F
Functional SOCS1 polymorphisms are associated with variation in obesity in whites.
Diabetes, obesity & metabolism 2009;11(3):196-203.
2009: Lauenborg Jeannet; Grarup Niels; Damm Peter; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Common type 2 diabetes risk gene variants associate with gestational diabetes.
The Journal of clinical endocrinology and metabolism 2009;94(1):145-50.
2009: Boesgaard Trine Welløv; Gjesing Anette Prior; Grarup Niels; Rutanen Jarno; Jansson Per-Anders; Hribal Marta Letizia; Sesti Giorgio; Fritsche Andreas; Stefan Norbert; Staiger Harald; Häring Hans; Smith Ulf; Laakso Markku; Pedersen Oluf; Hansen Torben;
Variant near ADAMTS9 known to associate with type 2 diabetes is related to insulin resistance in offspring of type 2 diabetes patients--EUGENE2 study.
PloS one 2009;4(9):e7236.
2009: Gjesing Anette P; Sparsø Thomas; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben; Olsen Niels V
No consistent effect of ADRB2 haplotypes on obesity, hypertension and quantitative traits of body fatness and blood pressure among 6,514 adult danes.
PloS one 2009;4(9):e7206.
2009: Kring Sofia I I; Werge Thomas; Holst Claus; Toubro Søren; Astrup Arne; Hansen Torben; Pedersen Oluf; Sørensen Thorkild I A
Polymorphisms of serotonin receptor 2A and 2C genes and COMT in relation to obesity and type 2 diabetes.
PloS one 2009;4(8):e6696.
2009: Rathcke Camilla Noelle; Holmkvist Johan; Husmoen Lise Lotte N; Hansen Torben; Pedersen Oluf; Vestergaard Henrik; Linneberg Allan
Association of polymorphisms of the CHI3L1 gene with asthma and atopy: a populations-based study of 6514 Danish adults.
PloS one 2009;4(7):e6106.
2009: Rathcke Camilla Noelle; Holmkvist Johan; Jørgensen Torben; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf Borbye; Vestergaard Henrik
Variation in CHI3LI in relation to type 2 diabetes and related quantitative traits.
PloS one 2009;4(5):e5469.
2009: Zimmermann Esther; Kring Sofia I I; Berentzen Tina L; Holst Claus; Pers Tune H; Hansen Torben; Pedersen Oluf; Sørensen Thorkild I A; Jess Tine
Fatness-associated FTO gene variant increases mortality independent of fatness--in cohorts of Danish men.
PloS one 2009;4(2):e4428.
2008: Nielsen Trine; Burgdorf Kristoffer Sølvsten; Grarup Niels; Borch-Johnsen Knut; Hansen Torben; Jørgensen Torben; Pedersen Oluf; Andersen Gitte
The KCNMB1 Glu65Lys polymorphism associates with reduced systolic and diastolic blood pressure in the Inter99 study of 5729 Danes.
Journal of hypertension 2008;26(11):2142-6.
2008: Lindegaard B; Hansen T; Hvid T; van Hall G; Plomgaard P; Ditlevsen S; Gerstoft J; Pedersen B K
The effect of strength and endurance training on insulin sensitivity and fat distribution in human immunodeficiency virus-infected patients with lipodystrophy.
The Journal of clinical endocrinology and metabolism 2008;93(10):3860-9.
2008: Jess T; Zimmermann E; Kring S I I; Berentzen T; Holst C; Toubro S; Astrup A; Hansen T; Pedersen O; Sørensen T I A
Impact on weight dynamics and general growth of the common FTO rs9939609: a longitudinal Danish cohort study.
International journal of obesity (2005) 2008;32(9):1388-94.
2008: Sparsø T; Andersen G; Albrechtsen A; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Wasson J; Permutt M A; Glaser B; Madsbad S; Pedersen O; Hansen T
Impact of polymorphisms in WFS1 on prediabetic phenotypes in a population-based sample of middle-aged people with normal and abnormal glucose regulation.
Diabetologia 2008;51(9):1646-52.
2008: Grarup Niels; Andersen Gitte; Krarup Nikolaj T; Albrechtsen Anders; Schmitz Ole; Jørgensen Torben; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
Association testing of novel type 2 diabetes risk alleles in the JAZF1, CDC123/CAMK1D, TSPAN8, THADA, ADAMTS9, and NOTCH2 loci with insulin release, insulin sensitivity, and obesity in a population-based sample of 4,516 glucose-tolerant middle-aged Danes.
Diabetes 2008;57(9):2534-40.
2008: Gutiérrez-Aguilar Ruth; Froguel Philippe; Hamid Yasmin H; Benmezroua Yamina; Jørgensen Torben; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf; Neve Bernadette
Genetic analysis of Kruppel-like zinc finger 11 variants in 5864 Danish individuals: potential effect on insulin resistance and modified signal transducer and activator of transcription-3 binding by promoter variant -1659G>C.
The Journal of clinical endocrinology and metabolism 2008;93(8):3128-35.
2008: Gonsorcíková Lucie; Pruhová Stepánka; Cinek Ondrej; Ek Jakob; Pelikánová Terezie; Jørgensen Torben; Eiberg Hans; Pedersen Oluf; Hansen Torben; Lebl Jan
Autosomal inheritance of diabetes in two families characterized by obesity and a novel H241Q mutation in NEUROD1.
Pediatric diabetes 2008;9(4 Pt 2):367-72.
2008: Jorsal A; Tarnow L; Lajer M; Ek J; Hansen T; Pedersen O; Parving H-H
The PPAR gamma 2 Pro12Ala variant predicts ESRD and mortality in patients with type 1 diabetes and diabetic nephropathy.
Molecular genetics and metabolism 2008;94(3):347-51.
2008: Grarup Niels; Andreasen Camilla H; Andersen Mette K; Albrechtsen Anders; Sandbaek Annelli; Lauritzen Torsten; Borch-Johnsen Knut; Jørgensen Torben; Schmitz Ole; Hansen Torben; Pedersen Oluf
The -250G>A promoter variant in hepatic lipase associates with elevated fasting serum high-density lipoprotein cholesterol modulated by interaction with physical activity in a study of 16,156 Danish subjects.
The Journal of clinical endocrinology and metabolism 2008;93(6):2294-9.
2008: Boesgaard T W; Zilinskaite J; Vänttinen M; Laakso M; Jansson P-A; Hammarstedt A; Smith U; Stefan N; Fritsche A; Häring H; Hribal M; Sesti G; Zobel D P; Pedersen O; Hansen T;
The common SLC30A8 Arg325Trp variant is associated with reduced first-phase insulin release in 846 non-diabetic offspring of type 2 diabetes patients--the EUGENE2 study.
Diabetologia 2008;51(5):816-20.
2008: Andersen Gitte; Burgdorf Kristoffer Sølvsten; Sparsø Thomas; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
AHSG tag single nucleotide polymorphisms associate with type 2 diabetes and dyslipidemia: studies of metabolic traits in 7,683 white Danish subjects.
Diabetes 2008;57(5):1427-32.
2008: Gjesing A P; Andersen G; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Association of the beta3-adrenergic receptor Trp64Arg polymorphism with common metabolic traits: studies of 7605 middle-aged white people.
Molecular genetics and metabolism 2008;94(1):90-7.
2008: Holmkvist J; Anthonsen S; Wegner L; Andersen G; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Pedersen O; Hansen T
Polymorphisms in AHI1 are not associated with type 2 diabetes or related phenotypes in Danes: non-replication of a genome-wide association result.
Diabetologia 2008;51(4):609-14.
2008: Grarup Niels; Stender-Petersen Kirstine L; Andersson Ehm A; Jørgensen Torben; Borch-Johnsen Knut; Sandbaek Annelli; Lauritzen Torsten; Schmitz Ole; Hansen Torben; Pedersen Oluf
Association of variants in the sterol regulatory element-binding factor 1 (SREBF1) gene with type 2 diabetes, glycemia, and insulin resistance: a study of 15,734 Danish subjects.
Diabetes 2008;57(4):1136-42.
2008: Hansen Torben; Pedersen Oluf Borbye;
[Genetics in non-autoimmune diabetes. The Danish Society of Endocrinology]
Ugeskrift for laeger 2008;170(12):1021.
2008: Clausen Tine D; Mathiesen Elisabeth R; Hansen Torben; Pedersen Oluf; Jensen Dorte M; Lauenborg Jeannet; Damm Peter
High prevalence of type 2 diabetes and pre-diabetes in adult offspring of women with gestational diabetes mellitus or type 1 diabetes: the role of intrauterine hyperglycemia.
Diabetes care 2008;31(2):340-6.
2008: Sparsø T; Andersen G; Nielsen T; Burgdorf K S; Gjesing A P; Nielsen A L; Albrechtsen A; Rasmussen S S; Jørgensen T; Borch-Johnsen K; Sandbaek A; Lauritzen T; Madsbad S; Hansen T; Pedersen O
The GCKR rs780094 polymorphism is associated with elevated fasting serum triacylglycerol, reduced fasting and OGTT-related insulinaemia, and reduced risk of type 2 diabetes.
Diabetologia 2008;51(1):70-5.
2008: Andreasen Camilla H; Stender-Petersen Kirstine L; Mogensen Mette S; Torekov Signe S; Wegner Lise; Andersen Gitte; Nielsen Arne L; Albrechtsen Anders; Borch-Johnsen Knut; Rasmussen Signe S; Clausen Jesper O; Sandbaek Annelli; Lauritzen Torsten; Hansen Lars; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Low physical activity accentuates the effect of the FTO rs9939609 polymorphism on body fat accumulation.
Diabetes 2008;57(1):95-101.
2008: Kring Sofia I I; Holst Claus; Zimmermann Esther; Jess Tine; Berentzen Tina; Toubro Søren; Hansen Torben; Astrup Arne; Pedersen Oluf; Sørensen Thorkild I A
FTO gene associated fatness in relation to body fat distribution and metabolic traits throughout a broad range of fatness.
PloS one 2008;3(8):e2958.
2008: Andreasen Camilla H; Mogensen Mette S; Borch-Johnsen Knut; Sandbaek Annelli; Lauritzen Torsten; Sørensen Thorkild I A; Hansen Lars; Almind Katrine; Jørgensen Torben; Pedersen Oluf; Hansen Torben
Non-replication of genome-wide based associations between common variants in INSIG2 and PFKP and obesity in studies of 18,014 Danes.
PloS one 2008;3(8):e2872.
2007: Grarup Niels; Rose Chrisian S; Andersson Ehm A; Andersen Gitte; Nielsen Arne L; Albrechtsen Anders; Clausen Jesper O; Rasmussen Signe S; Jørgensen Torben; Sandbaek Annelli; Lauritzen Torsten; Schmitz Ole; Hansen Torben; Pedersen Oluf
Studies of association of variants near the HHEX, CDKN2A/B, and IGF2BP2 genes with type 2 diabetes and impaired insulin release in 10,705 Danish subjects: validation and extension of genome-wide association studies.
Diabetes 2007;56(12):3105-11.
2007: Sparsø Thomas; Hussain Meena Shaheen; Borch-Johnsen Knut; Jørgensen Torben; Madsbad Sten; Hansen Torben; Pedersen Oluf; Andersen Gitte
Studies of association of the CASQ1 rs2275703 polymorphism in relation to type 2 diabetes and related quantitative metabolic traits among 7,088 Danish whites.
Molecular genetics and metabolism 2007;92(3):278-82.
2007: Hainerová Irena; Larsen Lesli H; Holst Birgitte; Finková Marie; Hainer Vojtech; Lebl Jan; Hansen Torben; Pedersen Oluf
Melanocortin 4 receptor mutations in obese Czech children: studies of prevalence, phenotype development, weight reduction response, and functional analysis.
The Journal of clinical endocrinology and metabolism 2007;92(9):3689-96.
2007: Ling C; Wegner L; Andersen G; Almgren P; Hansen T; Pedersen O; Groop L; Vaag A; Poulsen P
Impact of the peroxisome proliferator activated receptor-gamma coactivator-1beta (PGC-1beta) Ala203Pro polymorphism on in vivo metabolism, PGC-1beta expression and fibre type composition in human skeletal muscle.
Diabetologia 2007;50(8):1615-20.
2007: Boesgaard T W; Castella S I; Andersen G; Albrechtsen A; Sparsø T; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
A -243A-->G polymorphism upstream of the gene encoding GAD65 associates with lower levels of body mass index and glycaemia in a population-based sample of 5857 middle-aged White subjects.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(7):702-6.
2007: Albrechtsen Anders; Castella Sofie; Andersen Gitte; Hansen Torben; Pedersen Oluf; Nielsen Rasmus
A Bayesian multilocus association method: allowing for higher-order interaction in association studies.
Genetics 2007;176(2):1197-208.
2007: Grarup N; Albrechtsen A; Ek J; Borch-Johnsen K; Jørgensen T; Schmitz O; Hansen T; Pedersen O
Variation in the peroxisome proliferator-activated receptor delta gene in relation to common metabolic traits in 7,495 middle-aged white people.
Diabetologia 2007;50(6):1201-8.
2007: Jensen Dorit P; Andreasen Camilla H; Andersen Mette K; Hansen Lars; Eiberg Hans; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
The functional Pro129Thr variant of the FAAH gene is not associated with various fat accumulation phenotypes in a population-based cohort of 5,801 whites.
Journal of molecular medicine (Berlin, Germany) 2007;85(5):445-9.
2007: Gjesing A P; Andersen G; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of associations between the Arg389Gly polymorphism of the beta1-adrenergic receptor gene (ADRB1) and hypertension and obesity in 7677 Danish white subjects.
Diabetic medicine : a journal of the British Diabetic Association 2007;24(4):392-7.
2007: Wegner Lise; Andersen Gitte; Sparsø Thomas; Grarup Niels; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Common variation in LMNA increases susceptibility to type 2 diabetes and associates with elevated fasting glycemia and estimates of body fat and height in the general population: studies of 7,495 Danish whites.
Diabetes 2007;56(3):694-8.
2007: Gjesing A P; Andersen G; Burgdorf K S; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of the associations between functional beta2-adrenergic receptor variants and obesity, hypertension and type 2 diabetes in 7,808 white subjects.
Diabetologia 2007;50(3):563-8.
2007: Hansen Torben; Drivsholm Thomas; Urhammer Søren A; Palacios Rene T; Vølund Aage; Borch-Johnsen Knut; Pedersen Oluf
The BIGTT test: a novel test for simultaneous measurement of pancreatic beta-cell function, insulin sensitivity, and glucose tolerance.
Diabetes care 2007;30(2):257-62.
2007: Sparsø Thomas; Hussain Meena S; Andersen Gitte; Hainerova Irena; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Relationships between the functional PPARalpha Leu162Val polymorphism and obesity, type 2 diabetes, dyslipidaemia, and related quantitative traits in studies of 5799 middle-aged white people.
Molecular genetics and metabolism 2007;90(2):205-9.
2007: Larsen L H; Rose C S; Sparsø T; Overgaard J; Torekov S S; Grarup N; Jensen D P; Albrechtsen A; Andersen G; Ek J; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Genetic analysis of the estrogen-related receptor alpha and studies of association with obesity and type 2 diabetes.
International journal of obesity (2005) 2007;31(2):365-70.
2007: Pinterova D; Ek J; Kolostova K; Pruhova S; Novota P; Romzova M; Feigerlova E; Cerna M; Lebl J; Pedersen O; Hansen T
Six novel mutations in the GCK gene in MODY patients.
Clinical genetics 2007;71(1):95-6.
2007: Grarup Niels; Andersen Mette K; Andreasen Camilla H; Albrechtsen Anders; Borch-Johnsen Knut; Jørgensen Torben; Auwerx Johan; Schmitz Ole; Hansen Torben; Pedersen Oluf
Studies of the common DIO2 Thr92Ala polymorphism and metabolic phenotypes in 7342 Danish white subjects.
The Journal of clinical endocrinology and metabolism 2007;92(1):363-6.
2006: Hainerová Irena; Torekov Signe S; Ek Jakob; Finková Marie; Borch-Johnsen Knut; Jørgensen Torben; Madsen Ole D; Lebl Jan; Hansen Torben; Pedersen Oluf
Association between neuromedin U gene variants and overweight and obesity.
The Journal of clinical endocrinology and metabolism 2006;91(12):5057-63.
2006: Jensen Dorit P; Urhammer Søren A; Eiberg Hans; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Variation in CAPN10 in relation to type 2 diabetes, obesity and quantitative metabolic traits: studies in 6018 whites.
Molecular genetics and metabolism 2006;89(4):360-7.
2006: van Hove Els C; Hansen Torben; Dekker Jacqueline M; Reiling Erwin; Nijpels Giel; Jørgensen Torben; Borch-Johnsen Knut; Hamid Yasmin H; Heine Robert J; Pedersen Oluf; Maassen J Antonie; 't Hart Leen M
The HADHSC gene encoding short-chain L-3-hydroxyacyl-CoA dehydrogenase (SCHAD) and type 2 diabetes susceptibility: the DAMAGE study.
Diabetes 2006;55(11):3193-6.
2006: Torekov S S; Larsen L H; Andersen G; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Variants in the 5' region of the neuropeptide Y receptor Y2 gene (NPY2R) are associated with obesity in 5,971 white subjects.
Diabetologia 2006;49(11):2653-8.
2006: Wegner L; Andersen G; Albrechtsen A; Sparsø T; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Large-scale study of the -232C > G polymorphism of PCK1 in Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2006;23(10):1140-4.
2006: Koefoed Theil Pernille; Kessel Line; Hansen Torben; Lund-Andersen Henrik; Pedersen Oluf; Larsen Michael
Lens fluorescence in relation to glucose tolerance and genetic predisposition to type 2 diabetes mellitus in a population-based study.
Current eye research 2006;31(9):733-8.
2006: Grarup N; Urhammer S A; Ek J; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of the relationship between the ENPP1 K121Q polymorphism and type 2 diabetes, insulin resistance and obesity in 7,333 Danish white subjects.
Diabetologia 2006;49(9):2097-104.
2006: Feigerlová E; Pruhová S; Dittertová L; Lebl J; Pinterová D; Kolostová K; Cerná M; Pedersen O; Hansen T
Aetiological heterogeneity of asymptomatic hyperglycaemia in children and adolescents.
European journal of pediatrics 2006;165(7):446-52.
2006: Ek Jakob; Hansen Sara P; Lajer Maria; Nicot Carine; Boesgaard Trine W; Pruhova Stepanka; Johansen Anders; Albrechtsen Anders; Yderstraede Knud; Lauenborg Jeannet; Parrizas Marcelina; Boj Sylvia F; Jørgensen Torben; Borch-Johnsen Knut; Damm Peter; Ferrer Jorge; Lebl Jan; Pedersen Oluf; Hansen Torben
A novel -192c/g mutation in the proximal P2 promoter of the hepatocyte nuclear factor-4 alpha gene (HNF4A) associates with late-onset diabetes.
Diabetes 2006;55(6):1869-73.
2006: Nolsøe R L; Hamid Y H; Pociot F; Paulsen S; Andersen K M; Borch-Johnsen K; Drivsholm T; Hansen T; Pedersen O; Mandrup-Poulsen T
Association of a microsatellite in FASL to type II diabetes and of the FAS-670G>A genotype to insulin resistance.
Genes and immunity 2006;7(4):316-21.
2006: Eiberg H; Hansen L; Kjer B; Hansen T; Pedersen O; Bille M; Rosenberg T; Tranebjaerg L
Autosomal dominant optic atrophy associated with hearing impairment and impaired glucose regulation caused by a missense mutation in the WFS1 gene.
Journal of medical genetics 2006;43(5):435-40.
2006: Johansen A; Jensen D P; Bergholdt R; Mortensen H B; Pociot F; Nerup J; Hansen T; Pedersen O;
IRS1, KCNJ11, PPARgamma2 and HNF-1alpha: do amino acid polymorphisms in these candidate genes support a shared aetiology between type 1 and type 2 diabetes?
Diabetes, obesity & metabolism 2006;8(1):75-82.
2006: Andersen G; Overgaard J; Albrechtsen A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Studies of the association of the GNB3 825C>T polymorphism with components of the metabolic syndrome in white Danes.
Diabetologia 2006;49(1):75-82.
2005: Rose Christian S; Ek Jakob; Urhammer Søren A; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben
A -30G>A polymorphism of the beta-cell-specific glucokinase promoter associates with hyperglycemia in the general population of whites.
Diabetes 2005;54(10):3026-31.
2005: Johansen A; Ek J; Mortensen H B; Pedersen O; Hansen T
Half of clinically defined maturity-onset diabetes of the young patients in Denmark do not have mutations in HNF4A, GCK, and TCF1.
The Journal of clinical endocrinology and metabolism 2005;90(8):4607-14.
2005: Torekov Signe S; Larsen Lesli H; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Holst Jens J; Madsen Ole D; Hansen Torben; Pedersen Oluf
Evidence of an association between the Arg72 allele of the peptide YY and increased risk of type 2 diabetes.
Diabetes 2005;54(7):2261-5.
2005: Rose C S; Andersen G; Hamid Y H; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Pedersen O; Hansen T
Studies of relationships between the GLUT10 Ala206Thr polymorphism and impaired insulin secretion.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(7):946-9.
2005: Lauenborg Jeannet; Mathiesen Elisabeth; Hansen Torben; Glümer Charlotte; Jørgensen Torben; Borch-Johnsen Knut; Hornnes Peter; Pedersen Oluf; Damm Peter
The prevalence of the metabolic syndrome in a danish population of women with previous gestational diabetes mellitus is three-fold higher than in the general population.
The Journal of clinical endocrinology and metabolism 2005;90(7):4004-10.
2005: Larsen Thomas M; Larsen Lesli H; Torekov Signe K; Ek Jakob; Black Eva; Toubro Søren; Astrup Arne; Sørensen Thorkild I A; Hansen Torben; Pedersen Oluf
Novel variants in the putative peroxisome proliferator-activated receptor {gamma} promoter and relationships with obesity in men.
Obesity research 2005;13(6):953-8.
2005: 't Hart Leen M; Hansen Torben; Rietveld Ingrid; Dekker Jacqueline M; Nijpels Giel; Janssen George M C; Arp Pascal A; Uitterlinden André G; Jørgensen Torben; Borch-Johnsen Knut; Pols Huibert A P; Pedersen Oluf; van Duijn Cornelia M; Heine Robert J; Maassen J Antonie
Evidence that the mitochondrial leucyl tRNA synthetase (LARS2) gene represents a novel type 2 diabetes susceptibility gene.
Diabetes 2005;54(6):1892-5.
2005: Hansen Sara K; Nielsen Eva-Maria D; Ek Jakob; Andersen Gitte; Glümer Charlotte; Carstensen Bendix; Mouritzen Peter; Drivsholm Thomas; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Analysis of separate and combined effects of common variation in KCNJ11 and PPARG on risk of type 2 diabetes.
The Journal of clinical endocrinology and metabolism 2005;90(6):3629-37.
2005: Andersen G; Hansen T; Pedersen O
Genetics of common forms of glycaemia with pathological impact on vascular biology: are we on the right track?
Current molecular medicine 2005;5(3):261-74.
2005: Andersen G; Wegner L; Yanagisawa K; Rose C S; Lin J; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Hansen T; Spiegelman B M; Pedersen O
Evidence of an association between genetic variation of the coactivator PGC-1beta and obesity.
Journal of medical genetics 2005;42(5):402-7.
2005: Pearson E R; Pruhova S; Tack C J; Johansen A; Castleden H A J; Lumb P J; Wierzbicki A S; Clark P M; Lebl J; Pedersen O; Ellard S; Hansen T; Hattersley A T
Molecular genetics and phenotypic characteristics of MODY caused by hepatocyte nuclear factor 4alpha mutations in a large European collection.
Diabetologia 2005;48(5):878-85.
2005: Nielsen Eva-Maria D; Hansen Lars; Stissing Trine; Yanagisawa Keiko; Borch-Johnsen Knut; Poulsen Pernille; Vaag Allan; Hansen Torben; Pedersen Oluf
Studies of variations of the cyclin-dependent kinase inhibitor 1C and the cyclin-dependent kinase 4 genes in relation to type 2 diabetes mellitus and related quantitative traits.
Journal of molecular medicine (Berlin, Germany) 2005;83(5):353-61.
2005: Larsen Lesli H; Gjesing Anette P; Sørensen Thorkild I A; Hamid Yasmin H; Echwald Søren M; Toubro Søren; Black Eva; Astrup Arne; Hansen Torben; Pedersen Oluf
Mutation analysis of the preproghrelin gene: no association with obesity and type 2 diabetes.
Clinical biochemistry 2005;38(5):420-4.
2005: Ek Jakob; Rose Christian Schack; Jensen Dorit Packert; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Pedersen Oluf; Hansen Torben
The functional Thr130Ile and Val255Met polymorphisms of the hepatocyte nuclear factor-4alpha (HNF4A): gene associations with type 2 diabetes or altered beta-cell function among Danes.
The Journal of clinical endocrinology and metabolism 2005;90(5):3054-9.
2005: Sagen J V; Pearson E R; Johansen A; Spyer G; Søvik O; Pedersen O; Njølstad P R; Hattersley A T; Hansen T
Preserved insulin response to tolbutamide in hepatocyte nuclear factor-1alpha mutation carriers.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(4):406-9.
2005: Andersen Gitte; Wegner Lise; Jensen Dorit Packert; Glümer Charlotte; Tarnow Lise; Drivsholm Thomas; Poulsen Pernille; Hansen Sara Kristine; Nielsen Eva-Maria Damsgaard; Ek Jakob; Mouritzen Peter; Vaag Allan; Parving Hans-Henrik; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
PGC-1alpha Gly482Ser polymorphism associates with hypertension among Danish whites.
Hypertension 2005;45(4):565-70.
2005: Neve Bernadette; Fernandez-Zapico Martin E; Ashkenazi-Katalan Vered; Dina Christian; Hamid Yasmin H; Joly Erik; Vaillant Emmanuel; Benmezroua Yamina; Durand Emmanuelle; Bakaher Nicolas; Delannoy Valerie; Vaxillaire Martine; Cook Tiffany; Dallinga-Thie Geesje M; Jansen Hans; Charles Marie-Aline; Clément Karine; Galan Pilar; Hercberg Serge; Helbecque Nicole; Charpentier Guillaume; Prentki Marc; Hansen Torben; Pedersen Oluf; Urrutia Raul; Melloul Danielle; Froguel Philippe
Role of transcription factor KLF11 and its diabetes-associated gene variants in pancreatic beta cell function.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(13):4807-12.
2005: Hansen S K; Rose C S; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Pedersen O; Hansen T
Variation near the hepatocyte nuclear factor (HNF)-4alpha gene associates with type 2 diabetes in the Danish population.
Diabetologia 2005;48(3):452-8.
2005: Hamid Y H; Urhammer S A; Glümer C; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
The common T60N polymorphism of the lymphotoxin-alpha gene is associated with type 2 diabetes and other phenotypes of the metabolic syndrome.
Diabetologia 2005;48(3):445-51.
2005: Hamid Y H; Rose C S; Urhammer S A; Glümer C; Nolsøe R; Kristiansen O P; Mandrup-Poulsen T; Borch-Johnsen K; Jorgensen T; Hansen T; Pedersen O
Variations of the interleukin-6 promoter are associated with features of the metabolic syndrome in Caucasian Danes.
Diabetologia 2005;48(2):251-60.
2005: Hamid Y H; Vissing H; Holst B; Urhammer S A; Pyke C; Hansen S K; Glümer C; Borch-Johnsen K; Jørgensen T; Schwartz T W; Pedersen O; Hansen T
Studies of relationships between variation of the human G protein-coupled receptor 40 Gene and Type 2 diabetes and insulin release.
Diabetic medicine : a journal of the British Diabetic Association 2005;22(1):74-80.
2005: Andersen Kirstine L; Echwald Søren M; Larsen Lesli H; Hamid Yasmin H; Glümer Charlotte; Jørgensen Torben; Borch-Johnsen Knut; Andersen Teis; Sørensen Thorkild I A; Hansen Torben; Pedersen Oluf
Variation of the McKusick-Kaufman gene and studies of relationships with common forms of obesity.
The Journal of clinical endocrinology and metabolism 2005;90(1):225-30.
2004: Lauenborg J; Damm P; Ek J; Glümer C; Jørgensen T; Borch-Johnsen K; Vestergaard H; Hornnes P; Pedersen O; Hansen T
Studies of the Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene and the relationship to beta-cell function during an OGTT in glucose-tolerant women with and without previous gestational diabetes mellitus.
Diabetic medicine : a journal of the British Diabetic Association 2004;21(12):1310-5.
2004: Hamid Yasmin H; Urhammer Søren A; Jensen Dorit P; Glümer Charlotte; Borch-Johnsen Knut; Jørgensen Torben; Hansen Torben; Pedersen Oluf
Variation in the interleukin-6 receptor gene associates with type 2 diabetes in Danish whites.
Diabetes 2004;53(12):3342-5.
2004: Andersen Gitte; Wegner Lise; Rose Christian Schack; Xie Jianxin; Zhu Hao; Larade Kevin; Johansen Anders; Ek Jakob; Lauenborg Jeannet; Drivsholm Thomas; Borch-Johnsen Knut; Damm Peter; Hansen Torben; Bunn H Franklin; Pedersen Oluf
Variation in NCB5OR: studies of relationships to type 2 diabetes, maturity-onset diabetes of the young, and gestational diabetes mellitus.
Diabetes 2004;53(11):2992-7.
2004: Nielsen Eva-Maria D; Hansen Lars; Lajer Maria; Andersen Kirstine L; Echwald Søren M; Urhammer Søren A; Hansen Torben; Pedersen Oluf
A common polymorphism in the promoter of the IGF-I gene associates with increased fasting serum triglyceride levels in glucose-tolerant subjects.
Clinical biochemistry 2004;37(8):660-5.
2004: Johansen A; Nielsen E-M D; Andersen G; Hamid Y H; Jensen D P; Glümer C; Drivsholm T; Borch-Johnsen K; Jørgensen T; Hansen T; Pedersen O
Large-scale studies of the functional K variant of the butyrylcholinesterase gene in relation to Type 2 diabetes and insulin secretion.
Diabetologia 2004;47(8):1437-41.
2004: Gylvin T; Nolsøe R; Hansen T; Nielsen E M D; Bergholdt R; Karlsen A E; Billestrup N; Borch-Johnsen K; Pedersen O; Mandrup-Poulsen T; Nerup J; Pociot F
Mutation analysis of suppressor of cytokine signalling 3, a candidate gene in Type 1 diabetes and insulin sensitivity.
Diabetologia 2004;47(7):1273-7.
2004: Hansen S K; Gjesing A P; Rasmussen S K; Glümer C; Urhammer S A; Andersen G; Rose C S; Drivsholm T; Torekov S K; Jensen D P; Ekstrøm C T; Borch-Johnsen K; Jørgensen T; McCarthy M I; Hansen T; Pedersen O
Large-scale studies of the HphI insulin gene variable-number-of-tandem-repeats polymorphism in relation to Type 2 diabetes mellitus and insulin release.
Diabetologia 2004;47(6):1079-87.
2004: Lauenborg Jeannet; Hansen Torben; Jensen Dorte Møller; Vestergaard Henrik; Mølsted-Pedersen Lars; Hornnes Peter; Locht Henning; Pedersen Oluf; Damm Peter
Increasing incidence of diabetes after gestational diabetes: a long-term follow-up in a Danish population.
Diabetes care 2004;27(5):1194-9.
2004: Saudek Frantisek; Pruhová Stepánka; Boucek Peter; Lebl Jan; Adamec Milos; Ek Jakob; Pedersen Oluf; Hansen Torben
Maturity-onset diabetes of the young with end-stage nephropathy: a new indication for simultaneous pancreas and kidney transplantation?
Transplantation 2004;77(8):1298-301.
2003: Dalgaard Louise T; Andersen Gitte; Larsen Lesli H; Sørensen Thorkild I A; Andersen Teis; Drivsholm Thomas; Borch-Johnsen Knut; Fleckner Jan; Hansen Torben; Din Nanni; Pedersen Oluf
Mutational analysis of the UCP2 core promoter and relationships of variants with obesity.
Obesity research 2003;11(11):1420-7.
2003: Yanagisawa K; Hingstrup Larsen L; Andersen G; Drivsholm T; Cederberg A; Westergren R; Borch-Johnsen K; Pedersen O; Enerbäck S; Hansen T
The FOXC2 -512C>T variant is associated with hypertriglyceridaemia and increased serum C-peptide in Danish Caucasian glucose-tolerant subjects.
Diabetologia 2003;46(11):1576-80.
2003: Andersen Gitte; Rose Christian Schack; Hamid Yasmin Hassan; Drivsholm Thomas; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
Genetic variation of the GLUT10 glucose transporter (SLC2A10) and relationships to type 2 diabetes and intermediary traits.
Diabetes 2003;52(9):2445-8.
2003: Nielsen Eva-Maria D; Hansen Lars; Echwald Søren M; Drivsholm Thomas; Borch-Johnsen Knut; Ekstrøm Claus T; Hansen Torben; Pedersen Oluf
Evidence for an association between the Leu162Val polymorphism of the PPARalpha gene and decreased fasting serum triglyceride levels in glucose tolerant subjects.
Pharmacogenetics 2003;13(7):417-23.
2003: Pildal J; Lajer M; Hansen S K; Almind K; Ambye L; Borch-Johnsen K; Carstensen B; Hansen T; Pedersen O
Studies of variability in the islet amyloid polypeptide gene in relation to Type 2 diabetes.
Diabetic medicine : a journal of the British Diabetic Association 2003;20(6):491-4.
2003: Frayling Timothy M; Lindgren Cecilia M; Chevre Jean Claude; Menzel Stephan; Wishart Marie; Benmezroua Yamina; Brown Alison; Evans Julie C; Rao Pamidghantam Subba; Dina Christian; Lecoeur Cécile; Kanninen Timo; Almgren Peter; Bulman Michael P; Wang Youxiang; Mills James; Wright-Pascoe Rosemarie; Mahtani Melanie M; Prisco Francesco; Costa Angels; Cognet Ignacio; Hansen Torben; Pedersen Oluf; Ellard Sian; Tuomi Tiinamaija; Groop Leif C; Froguel Philippe; Hattersley Andrew T; Vaxillaire Martine
A genome-wide scan in families with maturity-onset diabetes of the young: evidence for further genetic heterogeneity.
Diabetes 2003;52(3):872-81.
2003: Pruhova S; Ek J; Lebl J; Sumnik Z; Saudek F; Andel M; Pedersen O; Hansen T
Genetic epidemiology of MODY in the Czech republic: new mutations in the MODY genes HNF-4alpha, GCK and HNF-1alpha.
Diabetologia 2003;46(2):291-5.
2003: Nielsen Eva-Maria D; Hansen Lars; Carstensen Bendix; Echwald Søren M; Drivsholm Thomas; Glümer Charlotte; Thorsteinsson Birger; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
The E23K variant of Kir6.2 associates with impaired post-OGTT serum insulin response and increased risk of type 2 diabetes.
Diabetes 2003;52(2):573-7.
2002: Rasmussen Søren K; Urhammer Søren A; Berglund Lars; Jensen Jan N; Hansen Lars; Echwald Søren M; Borch-Johnsen Knut; Horikawa Yukio; Mashima Hirosato; Lithell Hans; Cox Nancy J; Hansen Torben; Bell Graeme I; Pedersen Oluf
Variants within the calpain-10 gene on chromosome 2q37 (NIDDM1) and relationships to type 2 diabetes, insulin resistance, and impaired acute insulin secretion among Scandinavian Caucasians.
Diabetes 2002;51(12):3561-7.
2002: Bulman M P; Harries L W; Hansen T; Shepherd M; Kelly W F; Hattersley A T; Ellard S
Abnormal splicing of hepatocyte nuclear factor 1 alpha in maturity-onset diabetes of the young.
Diabetologia 2002;45(10):1463-7.
2002: Mitchell S M S; Vaxillaire M; Thomas H; Parrizas M; Benmezroua Y; Costa A; Hansen T; Owen K R; Tuomi T; Pirie F; Ryffel G U; Ferrer J; Froguel P; Hattersley A T; Frayling T M
Rare variants identified in the HNF- 4 alpha beta-cell-specific promoter and alternative exon 1 lack biological significance in maturity onset diabetes of the young and young onset Type II diabetes.
Diabetologia 2002;45(9):1344-8.
2002: Hansen Sara K; Párrizas Marcelina; Jensen Maria L; Pruhova Stepanka; Ek Jakob; Boj Sylvia F; Johansen Anders; Maestro Miguel A; Rivera Francisca; Eiberg Hans; Andel Michal; Lebl Jan; Pedersen Oluf; Ferrer Jorge; Hansen Torben
Genetic evidence that HNF-1alpha-dependent transcriptional control of HNF-4alpha is essential for human pancreatic beta cell function.
The Journal of clinical investigation 2002;110(6):827-33.
2002: Pedersen Oluf Borbye; Hansen Torben; Hansen Lars; Echwald Søren M; Urhammer Søren A
[Chasing the genetic determinants of the presumed polygenic forms of type 2 diabetes. Status and perspectives]
Ugeskrift for laeger 2002;164(16):2163-6.
2002: Hansen Torben; Urhammer Søren A; Pedersen Oluf Borbye
[Maturity-onset diabetes of the young--MODY. Molecular-genetic, pathophysiological and clinical characteristics]
Ugeskrift for laeger 2002;164(15):2017-22.
2002: Stride A; Vaxillaire M; Tuomi T; Barbetti F; Njølstad P R; Hansen T; Costa A; Conget I; Pedersen O; Søvik O; Lorini R; Groop L; Froguel P; Hattersley A T
The genetic abnormality in the beta cell determines the response to an oral glucose load.
Diabetologia 2002;45(3):427-35.
2002: Echwald Søren M; Bach Helle; Vestergaard Henrik; Richelsen Bjørn; Kristensen Kurt; Drivsholm Thomas; Borch-Johnsen Knut; Hansen Torben; Pedersen Oluf
A P387L variant in protein tyrosine phosphatase-1B (PTP-1B) is associated with type 2 diabetes and impaired serine phosphorylation of PTP-1B in vitro.
Diabetes 2002;51(1):1-6.
2002: Hansen Torben
Type 2 diabetes mellitus--a multifactorial disease.
Annales Universitatis Mariae Curie-Sklodowska. Sectio D: Medicina 2002;57(1):544-9.
2001: Ek J; Andersen G; Urhammer S A; Gaede P H; Drivsholm T; Borch-Johnsen K; Hansen T; Pedersen O
Mutation analysis of peroxisome proliferator-activated receptor-gamma coactivator-1 (PGC-1) and relationships of identified amino acid polymorphisms to Type II diabetes mellitus.
Diabetologia 2001;44(12):2220-6.
2001: Hansen T; Ambye L; Grarup N; Hansen L; Echwald S M; Ferrer J; Pedersen O
Genetic variability of the SUR1 promoter in relation to beta-cell function and Type II diabetes mellitus.
Diabetologia 2001;44(10):1330-4.
2001: Ek J; Grarup N; Urhammer S A; Gaede P H; Drivsholm T; Borch-Johnsen K; Hansen T; Pedersen O
Studies of the variability of the hepatocyte nuclear factor-1beta (HNF-1beta / TCF2) and the dimerization cofactor of HNF-1 (DcoH / PCBD) genes in relation to type 2 diabetes mellitus and beta-cell function.
Human mutation 2001;18(4):356-7.
2001: Ek J; Andersen G; Urhammer S A; Hansen L; Carstensen B; Borch-Johnsen K; Drivsholm T; Berglund L; Hansen T; Lithell H; Pedersen O
Studies of the Pro12Ala polymorphism of the peroxisome proliferator-activated receptor-gamma2 (PPAR-gamma2) gene in relation to insulin sensitivity among glucose tolerant caucasians.
Diabetologia 2001;44(9):1170-6.
2001: Dalgaard L T; Hansen T; Urhammer S A; Drivsholm T; Borch-Johnsen K; Pedersen O
The uncoupling protein 3 -55 C -->T variant is not associated with Type II diabetes mellitus in Danish subjects.
Diabetologia 2001;44(8):1065-7.
2001: Tarnow L; Grarup N; Hansen T; Parving H H; Pedersen O
Diabetic microvascular complications are not associated with two polymorphisms in the GLUT-1 and PC-1 genes regulating glucose metabolism in Caucasian type 1 diabetic patients.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2001;16(8):1653-6.
2001: Møller A M; Jensen N M; Pildal J; Drivsholm T; Borch-Johnsen K; Urhammer S A; Hansen T; Pedersen O
Studies of genetic variability of the glucose transporter 2 promoter in patients with type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 2001;86(5):2181-6.
2001: Dalgaard L T; Sørensen T I; Drivsholm T; Borch-Johnsen K; Andersen T; Hansen T; Pedersen O
A prevalent polymorphism in the promoter of the UCP3 gene and its relationship to body mass index and long term body weight change in the Danish population.
The Journal of clinical endocrinology and metabolism 2001;86(3):1398-402.
2001: Hansen L; Jensen J N; Ekstrøm C T; Vestergaard H; Hansen T; Pedersen O
Studies of variability in the PTEN gene among Danish caucasian patients with Type II diabetes mellitus.
Diabetologia 2001;44(2):237-40.
2001: Jensen J N; Hansen L; Ekstrøm C T; Pociot F; Nerup J; Hansen T; Pedersen O
Polymorphisms in the neurogenin 3 gene (NEUROG) and their relation to altered insulin secretion and diabetes in the Danish Caucasian population.
Diabetologia 2001;44(1):123-6.
2000: Urhammer S A; Hansen T; Borch-Johnsen K; Pedersen O
Studies of the synergistic effect of the Trp/Arg64 polymorphism of the beta3-adrenergic receptor gene and the -3826 A-->G variant of the uncoupling protein-1 gene on features of obesity and insulin resistance in a population-based sample of 379 young Danish subjects.
The Journal of clinical endocrinology and metabolism 2000;85(9):3151-4.
2000: Rasmussen S K; Urhammer S A; Pizzuti A; Echwald S M; Ekstrøm C T; Hansen L; Hansen T; Borch-Johnsen K; Frittitta L; Trischitta V; Pedersen O
The K121Q variant of the human PC-1 gene is not associated with insulin resistance or type 2 diabetes among Danish Caucasians.
Diabetes 2000;49(9):1608-11.
2000: Rasmussen S K; Urhammer S A; Hansen T; Almind K; Møller A M; Borch-Johnsen K; Pedersen O
Variability of the insulin receptor substrate-1, hepatocyte nuclear factor-1alpha (HNF-1alpha), HNF-4alpha, and HNF-6 genes and size at birth in a population-based sample of young Danish subjects.
The Journal of clinical endocrinology and metabolism 2000;85(8):2951-3.
2000: Hansen L; Jensen J N; Urioste S; Petersen H V; Pociot F; Eiberg H; Kristiansen O P; Hansen T; Serup P; Nerup J; Pedersen O
NeuroD/BETA2 gene variability and diabetes: no associations to late-onset type 2 diabetes but an A45 allele may represent a susceptibility marker for type 1 diabetes among Danes. Danish Study Group of Diabetes in Childhood, and the Danish IDDM Epidemiology and Genetics Group.
Diabetes 2000;49(5):876-8.
2000: Rasmussen S K; Urhammer S A; Jensen J N; Hansen T; Borch-Johnsen K; Pedersen O
The -238 and -308 G-->A polymorphisms of the tumor necrosis factor alpha gene promoter are not associated with features of the insulin resistance syndrome or altered birth weight in Danish Caucasians.
The Journal of clinical endocrinology and metabolism 2000;85(4):1731-4.
2000: Rasmussen S K; Lautier C; Hansen L; Echwald S M; Hansen T; Ekstrøm C T; Urhammer S A; Borch-Johnsen K; Grigorescu F; Smith R J; Pedersen O
Studies of the variability of the genes encoding the insulin-like growth factor I receptor and its ligand in relation to type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 2000;85(4):1606-10.
2000: Hansen L; Urioste S; Petersen H V; Jensen J N; Eiberg H; Barbetti F; Serup P; Hansen T; Pedersen O
Missense mutations in the human insulin promoter factor-1 gene and their relation to maturity-onset diabetes of the young and late-onset type 2 diabetes mellitus in caucasians.
The Journal of clinical endocrinology and metabolism 2000;85(3):1323-6.
2000: Hansen L; Reneland R; Berglund L; Rasmussen S K; Hansen T; Lithell H; Pedersen O
Polymorphism in the glycogen-associated regulatory subunit of type 1 protein phosphatase (PPP1R3) gene and insulin sensitivity.
Diabetes 2000;49(2):298-301.
1999: Dalgaard L T; Sørensen T I; Andersen T; Hansen T; Pedersen O
An untranslated insertion variant in the uncoupling protein 2 gene is not related to body mass index and changes in body weight during a 26-year follow-up in Danish Caucasian men.
Diabetologia 1999;42(12):1413-6.
1999: Almind K; Frederiksen S K; Bernal D; Hansen T; Ambye L; Urhammer S; Ekstrøm C T; Berglund L; Reneland R; Lithell H; White M F; Van Obberghen E; Pedersen O
Search for variants of the gene-promoter and the potential phosphotyrosine encoding sequence of the insulin receptor substrate-2 gene: evaluation of their relation with alterations in insulin secretion and insulin sensitivity.
Diabetologia 1999;42(10):1244-9.
1999: Møller A M; Ek J; Durviaux S M; Urhammer S A; Clausen J O; Eiberg H; Hansen T; Rousseau G G; Lemaigre F P; Pedersen O
Hepatocyte nuclear factor-6: associations between genetic variability and type II diabetes and between genetic variability and estimates of insulin secretion.
Diabetologia 1999;42(8):1011-6.
1999: Almind K; Ahlgren M G; Hansen T; Urhammer S A; Clausen J O; Pedersen O
Discovery of a Met300Val variant in Shc and studies of its relationship to birth weight and length, impaired insulin secretion, insulin resistance, and type 2 diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1999;84(6):2241-4.
1999: Dalgaard L T; Hansen T; Urhammer S A; Clausen J O; Eiberg H; Pedersen O
Intermediate expansions of a GAA repeat in the frataxin gene are not associated with type 2 diabetes or altered glucose-induced beta-cell function in Danish Caucasians.
Diabetes 1999;48(4):914-7.
1999: Hansen L; Fjordvang H; Rasmussen S K; Vestergaard H; Echwald S M; Hansen T; Alessi D; Shenolikar S; Saltiel A R; Barbetti F; Pedersen O
Mutational analysis of the coding regions of the genes encoding protein kinase B-alpha and -beta, phosphoinositide-dependent protein kinase-1, phosphatase targeting to glycogen, protein phosphatase inhibitor-1, and glycogenin: lessons from a search for genetic variability of the insulin-stimulated glycogen synthesis pathway of skeletal muscle in NIDDM patients.
Diabetes 1999;48(2):403-7.
1999: Møller A M; Dalgaard L T; Ambye L; Hansen L; Schmitz O; Hansen T; Pedersen O
A novel Phe75fsdelT mutation in the hepatocyte nuclear factor-4alpha gene in a Danish pedigree with maturity-onset diabetes of the young.
The Journal of clinical endocrinology and metabolism 1999;84(1):367-9.
1998: Møller A M; Dalgaard L T; Pociot F; Nerup J; Hansen T; Pedersen O
Mutations in the hepatocyte nuclear factor-1alpha gene in Caucasian families originally classified as having Type I diabetes.
Diabetologia 1998;41(12):1528-31.
1998: Urhammer S A; Hansen T; Ekstrøm C T; Eiberg H; Pedersen O
The Ala/Val98 polymorphism of the hepatocyte nuclear factor-1alpha gene contributes to the interindividual variation in serum C-peptide response during an oral glucose tolerance test: evidence from studies of 231 glucose-tolerant first degree relatives of type 2 diabetic probands.
The Journal of clinical endocrinology and metabolism 1998;83(12):4506-9.
1998: Urhammer S A; Møller A M; Nyholm B; Ekstrøm C T; Eiberg H; Clausen J O; Hansen T; Pedersen O; Schmitz O
The effect of two frequent amino acid variants of the hepatocyte nuclear factor-1alpha gene on estimates of the pancreatic beta-cell function in Caucasian glucose-tolerant first-degree relatives of type 2 diabetic patients.
The Journal of clinical endocrinology and metabolism 1998;83(11):3992-5.
1998: Almind K; Ambye L; Urhammer S A; Hansen T; Echwald S M; Holst J J; Gromada J; Thorens B; Pedersen O
Discovery of amino acid variants in the human glucose-dependent insulinotropic polypeptide (GIP) receptor: the impact on the pancreatic beta cell responses and functional expression studies in Chinese hamster fibroblast cells.
Diabetologia 1998;41(10):1194-8.
1998: Almind K; Frederiksen S K; Ahlgren M G; Urhammer S; Hansen T; Clausen J O; Pedersen O
Common amino acid substitutions in insulin receptor substrate-4 are not associated with Type II diabetes mellitus or insulin resistance.
Diabetologia 1998;41(8):969-74.
1998: Urhammer S A; Hansen T; Clausen J O; Eiberg H; Pedersen O
The g/a nucleotide variant at position -30 in the beta-cell-specific glucokinase gene promoter has no impact on the beta-cell function in Danish Caucasians.
Diabetes 1998;47(8):1359-61.
1998: Hansen T; Echwald S M; Hansen L; Møller A M; Almind K; Clausen J O; Urhammer S A; Inoue H; Ferrer J; Bryan J; Aguilar-Bryan L; Permutt M A; Pedersen O
Decreased tolbutamide-stimulated insulin secretion in healthy subjects with sequence variants in the high-affinity sulfonylurea receptor gene.
Diabetes 1998;47(4):598-605.
1997: Urhammer S A; Dalgaard L T; Sørensen T I; Møller A M; Andersen T; Tybjaerg-Hansen A; Hansen T; Clausen J O; Vestergaard H; Pedersen O
Mutational analysis of the coding region of the uncoupling protein 2 gene in obese NIDDM patients: impact of a common amino acid polymorphism on juvenile and maturity onset forms of obesity and insulin resistance.
Diabetologia 1997;40(10):1227-30.
1997: Møller A M; Urhammer S A; Dalgaard L T; Reneland R; Berglund L; Hansen T; Clausen J O; Lithell H; Pedersen O
Studies of the genetic variability of the coding region of the hepatocyte nuclear factor-4alpha in Caucasians with maturity onset NIDDM.
Diabetologia 1997;40(8):980-3.
1997: Hansen L; Arden K C; Rasmussen S B; Viars C S; Vestergaard H; Hansen T; Møller A M; Woodgett J R; Pedersen O
Chromosomal mapping and mutational analysis of the coding region of the glycogen synthase kinase-3alpha and beta isoforms in patients with NIDDM.
Diabetologia 1997;40(8):940-6.
1997: Hansen L; Hansen T; Clausen J O; Echwald S M; Urhammer S A; Rasmussen S K; Pedersen O
The Val985Met insulin-receptor variant in the Danish Caucasian population: lack of associations with non-insulin-dependent diabetes mellitus or insulin resistance.
American journal of human genetics 1997;60(6):1532-5.
1997: Urhammer S A; Hansen T; Jensen L B; Clausen J O; Hansen L; Chui K C; Pedersen O
Studies of the impact of a liver glucokinase promoter variant on glucose tolerance and insulin sensitivity index.
The Journal of clinical endocrinology and metabolism 1997;82(6):1786-9.
1997: Urhammer S A; Fridberg M; Hansen T; Rasmussen S K; Møller A M; Clausen J O; Pedersen O
A prevalent amino acid polymorphism at codon 98 in the hepatocyte nuclear factor-1alpha gene is associated with reduced serum C-peptide and insulin responses to an oral glucose challenge.
Diabetes 1997;46(5):912-6.
1997: Urhammer S A; Rasmussen S K; Kaisaki P J; Oda N; Yamagata K; Møller A M; Fridberg M; Hansen L; Hansen T; Bell G I; Pedersen O
Genetic variation in the hepatocyte nuclear factor-1 alpha gene in Danish Caucasians with late-onset NIDDM.
Diabetologia 1997;40(4):473-5.
1997: Hansen T; Eiberg H; Rouard M; Vaxillaire M; Møller A M; Rasmussen S K; Fridberg M; Urhammer S A; Holst J J; Almind K; Echwald S M; Hansen L; Bell G I; Pedersen O
Novel MODY3 mutations in the hepatocyte nuclear factor-1alpha gene: evidence for a hyperexcitability of pancreatic beta-cells to intravenous secretagogues in a glucose-tolerant carrier of a P447L mutation.
Diabetes 1997;46(4):726-30.
1997: Hansen T; Andersen C B; Echwald S M; Urhammer S A; Clausen J O; Vestergaard H; Owens D; Hansen L; Pedersen O
Identification of a common amino acid polymorphism in the p85alpha regulatory subunit of phosphatidylinositol 3-kinase: effects on glucose disappearance constant, glucose effectiveness, and the insulin sensitivity index.
Diabetes 1997;46(3):494-501.
1996: Koefoed Theil P; Hansen T; Larsen M; Pedersen O; Lund-Andersen H
Lens autofluorescence is increased in newly diagnosed patients with NIDDM.
Diabetologia 1996;39(12):1524-7.
1996: Yamagata K; Oda N; Kaisaki P J; Menzel S; Furuta H; Vaxillaire M; Southam L; Cox R D; Lathrop G M; Boriraj V V; Chen X; Cox N J; Oda Y; Yano H; Le Beau M M; Yamada S; Nishigori H; Takeda J; Fajans S S; Hattersley A T; Iwasaki N; Hansen T; Pedersen O; Polonsky K S; Bell G I
Mutations in the hepatocyte nuclear factor-1alpha gene in maturity-onset diabetes of the young (MODY3)
Nature 1996;384(6608):455-8.
1996: Urhammer S A; Clausen J O; Hansen T; Pedersen O
Insulin sensitivity and body weight changes in young white carriers of the codon 64 amino acid polymorphism of the beta 3-adrenergic receptor gene.
Diabetes 1996;45(8):1115-20.
1995: Vestergaard H; Bjørbaek C; Hansen T; Larsen F S; Granner D K; Pedersen O
Impaired activity and gene expression of hexokinase II in muscle from non-insulin-dependent diabetes mellitus patients.
The Journal of clinical investigation 1995;96(6):2639-45.
1995: Clausen J O; Hansen T; Bjørbaek C; Echwald S M; Urhammer S A; Rasmussen S; Andersen C B; Hansen L; Almind K; Winther K
Insulin resistance: interactions between obesity and a common variant of insulin receptor substrate-1.
Lancet 1995;346(8972):397-402.
1995: Hansen L; Hansen T; Vestergaard H; Bjørbaek C; Echwald S M; Clausen J O; Chen Y H; Chen M X; Cohen P T; Pedersen O
A widespread amino acid polymorphism at codon 905 of the glycogen-associated regulatory subunit of protein phosphatase-1 is associated with insulin resistance and hypersecretion of insulin.
Human molecular genetics 1995;4(8):1313-20.
1995: Vestergaard H; Klein H H; Hansen T; Müller J; Skovby F; Bjørbaek C; Røder M E; Pedersen O
Severe insulin-resistant diabetes mellitus in patients with congenital muscle fiber type disproportion myopathy.
The Journal of clinical investigation 1995;95(4):1925-32.
1995: Echwald S M; Bjørbaek C; Hansen T; Clausen J O; Vestergaard H; Zierath J R; Printz R L; Granner D K; Pedersen O
Identification of four amino acid substitutions in hexokinase II and studies of relationships to NIDDM, glucose effectiveness, and insulin sensitivity.
Diabetes 1995;44(3):347-53.
1995: Bjørbaek C; Vik T A; Echwald S M; Yang P Y; Vestergaard H; Wang J P; Webb G C; Richmond K; Hansen T; Erikson R L
Cloning of a human insulin-stimulated protein kinase (ISPK-1) gene and analysis of coding regions and mRNA levels of the ISPK-1 and the protein phosphatase-1 genes in muscle from NIDDM patients.
Diabetes 1995;44(1):90-7.
1994: Chen Y H; Hansen L; Chen M X; Bjørbaek C; Vestergaard H; Hansen T; Cohen P T; Pedersen O
Sequence of the human glycogen-associated regulatory subunit of type 1 protein phosphatase and analysis of its coding region and mRNA level in muscle from patients with NIDDM.
Diabetes 1994;43(10):1234-41.
1994: Bjørbaek C; Echwald S M; Hubricht P; Vestergaard H; Hansen T; Zierath J; Pedersen O
Genetic variants in promoters and coding regions of the muscle glycogen synthase and the insulin-responsive GLUT4 genes in NIDDM.
Diabetes 1994;43(8):976-83.
1993: Hansen T; Bjørbaek C; Vestergaard H; Grønskov K; Bak J F; Pedersen O
Expression of insulin receptor spliced variants and their functional correlates in muscle from patients with non-insulin-dependent diabetes mellitus.
The Journal of clinical endocrinology and metabolism 1993;77(6):1500-5.
1993: Almind K; Bjørbaek C; Vestergaard H; Hansen T; Echwald S; Pedersen O
Aminoacid polymorphisms of insulin receptor substrate-1 in non-insulin-dependent diabetes mellitus.
Lancet 1993;342(8875):828-32.

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