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Michael Hanson

Research Profile

Concepts & Ideas

Procedures

X Ray Crystallography

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

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Bacteriophage T4

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Publications

TOP 3
Eugene Chun; Mark T Griffith; Michael A Hanson; Vsevolod Katritch; Joshua Kunken; Wei Liu; Christopher B Roth; Aaron A Thompson; Fei Xu; Vadim Cherezov; Raymond C Stevens
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors.
Michael A Hanson; Euijung Jo; Peter Kuhn; Greg Reinhart; Hugh Rosen; Christopher B Roth; M Germana Sanna; Stephen Schuerer; Fiona L Scott; Stuart M Cahalan; Bryan Clemons; Hans Desale; Mark T Griffith; Gye Won Han; Raymond C Stevens
Crystal structure of a lipid G protein-coupled receptor.
Ellen Y T Chien; Wei Liu; Qiang Zhao; Vsevolod Katritch; Gye Won Han; Michael A Hanson; Lei Shi; Amy Hauck Newman; Jonathan A Javitch; Vadim Cherezov; Raymond C Stevens
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.

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All Publications

2012: Eugene Chun; Mark T Griffith; Michael A Hanson; Vsevolod Katritch; Joshua Kunken; Wei Liu; Christopher B Roth; Aaron A Thompson; Fei Xu; Vadim Cherezov; Raymond C Stevens
Fusion partner toolchest for the stabilization and crystallization of G protein-coupled receptors.
Structure (London, England : 1993) 2012;20(6):967-76.
2012: Michael A Hanson; Euijung Jo; Peter Kuhn; Greg Reinhart; Hugh Rosen; Christopher B Roth; M Germana Sanna; Stephen Schuerer; Fiona L Scott; Stuart M Cahalan; Bryan Clemons; Hans Desale; Mark T Griffith; Gye Won Han; Raymond C Stevens
Crystal structure of a lipid G protein-coupled receptor.
Science (New York, N.Y.) 2012;335(6070):851-5.
2010: Ellen Y T Chien; Wei Liu; Qiang Zhao; Vsevolod Katritch; Gye Won Han; Michael A Hanson; Lei Shi; Amy Hauck Newman; Jonathan A Javitch; Vadim Cherezov; Raymond C Stevens
Structure of the human dopamine D3 receptor in complex with a D2/D3 selective antagonist.
Science (New York, N.Y.) 2010;330(6007):1091-5.
2009: Vadim Cherezov; Michael A Hanson; Mark T Griffith; Mark C Hilgart; Ruslan Sanishvili; Venugopalan Nagarajan; Sergey Stepanov; Robert F Fischetti; Peter Kuhn; Raymond C Stevens
Rastering strategy for screening and centring of microcrystal samples of human membrane proteins with a sub-10 microm size X-ray synchrotron beam.
Journal of the Royal Society, Interface / the Royal Society 2009;6 Suppl 5():S587-97.
2009: Vsevolod Katritch; Kimberly A Reynolds; Vadim Cherezov; Michael A Hanson; Christopher B Roth; Mark Yeager; Ruben Abagyan
Analysis of full and partial agonists binding to beta2-adrenergic receptor suggests a role of transmembrane helix V in agonist-specific conformational changes.
Journal of molecular recognition : JMR 2009;22(4):307-18.
2009: Michael A Hanson; Raymond C Stevens
Discovery of new GPCR biology: one receptor structure at a time.
Structure (London, England : 1993) 2009;17(1):8-14.
2008: Veli-Pekka Jaakola; Mark T Griffith; Michael A Hanson; Vadim Cherezov; Ellen Y T Chien; J Robert Lane; Adriaan P IJzerman; Raymond C Stevens
The 2.6 angstrom crystal structure of a human A2A adenosine receptor bound to an antagonist.
Science (New York, N.Y.) 2008;322(5905):1211-7.
2008: Michael A Hanson; Vadim Cherezov; Mark T Griffith; Christopher B Roth; Veli-Pekka Jaakola; Ellen Y T Chien; Jeffrey Velasquez; Peter Kuhn; Raymond C Stevens
A specific cholesterol binding site is established by the 2.8 A structure of the human beta2-adrenergic receptor.
Structure (London, England : 1993) 2008;16(6):897-905.
2008: Guillermo A Asmar-Rovira; Aloysha M Asseo-García; Orestes Quesada; Michael A Hanson; Anchi Cheng; Carlos Nogueras; José A Lasalde-Dominicci; Raymond C Stevens
Biophysical and ion channel functional characterization of the Torpedo californica nicotinic acetylcholine receptor in varying detergent-lipid environments.
The Journal of membrane biology 2008;223(1):13-26.
2008: Christopher B Roth; Michael A Hanson; Raymond C Stevens
Stabilization of the human beta2-adrenergic receptor TM4-TM3-TM5 helix interface by mutagenesis of Glu122(3.41), a critical residue in GPCR structure.
Journal of molecular biology 2008;376(5):1305-19.
2008: Alexander I Alexandrov; Mauro Mileni; Ellen Y T Chien; Michael A Hanson; Raymond C Stevens
Microscale fluorescent thermal stability assay for membrane proteins.
Structure (London, England : 1993) 2008;16(3):351-9.
2007: Vadim Cherezov; Daniel M Rosenbaum; Michael A Hanson; Søren G F Rasmussen; Foon Sun Thian; Tong Sun Kobilka; Hee-Jung Choi; Peter Kuhn; William I Weis; Brian K Kobilka; Raymond C Stevens
High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor.
Science (New York, N.Y.) 2007;318(5854):1258-65.
2007: Daniel M Rosenbaum; Vadim Cherezov; Michael A Hanson; Søren G F Rasmussen; Foon Sun Thian; Tong Sun Kobilka; Hee-Jung Choi; Xiao-Jie Yao; William I Weis; Raymond C Stevens; Brian K Kobilka
GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function.
Science (New York, N.Y.) 2007;318(5854):1266-73.
2007: Michael A Hanson; Alexei Brooun; Kent A Baker; Veli-Pekka Jaakola; Chris Roth; Ellen Y T Chien; Alexander Alexandrov; Jeffrey Velasquez; Leila Davis; Mark Griffith; Kin Moy; Barbie K Ganser-Pornillos; Yuanzi Hua; Peter Kuhn; Sam Ellis; Mark Yeager; Raymond C Stevens
Profiling of membrane protein variants in a baculovirus system by coupling cell-surface detection with small-scale parallel expression.
Protein expression and purification 2007;56(1):85-92.
2005: Joseph W Arndt; Jenny Gu; Lukasz Jaroszewski; Robert Schwarzenbacher; Michael A Hanson; Frank J Lebeda; Raymond C Stevens
The structure of the neurotoxin-associated protein HA33/A from Clostridium botulinum suggests a reoccurring beta-trefoil fold in the progenitor toxin complex.
Journal of molecular biology 2005;346(4):1083-93.
2002: Michael H Bracey; Michael A Hanson; Kim R Masuda; Raymond C Stevens; Benjamin F Cravatt
Structural adaptations in a membrane enzyme that terminates endocannabinoid signaling.
Science (New York, N.Y.) 2002;298(5599):1793-6.
2000: Michael A Hanson; Raymond C Stevens
Cocrystal structure of synaptobrevin-II bound to botulinum neurotoxin type B at 2.0 A resolution.
Nature structural biology 2000;7(8):687-92.