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Stephen Hanson

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Mary J Heeb; Ulla M Marzec; A Gruber; Stephen R Hanson
Antithrombotic activity of protein S infused without activated protein C in a baboon thrombosis model.
Jingshu Wu; B Min Yun; Anna M Fallon; Stephen R Hanson; Cyrus K Aidun; Ajit P Yoganathan
Numerical investigation of the effects of channel geometry on platelet activation and blood damage.
Qiufang Cheng; Erik Tucker; Meghann S Pine; India Sisler; Anton Matafonov; Mao-Fu Sun; Tara C White-Adams; Ann Stephanie Smith; Stephen R Hanson; Owen J T McCarty; Thomas Renné; András Gruber; David Gailani
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.

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All Publications

2012: Mary J Heeb; Ulla M Marzec; A Gruber; Stephen R Hanson
Antithrombotic activity of protein S infused without activated protein C in a baboon thrombosis model.
Thrombosis and haemostasis 2012;107(4):690-8.
2011: Jingshu Wu; B Min Yun; Anna M Fallon; Stephen R Hanson; Cyrus K Aidun; Ajit P Yoganathan
Numerical investigation of the effects of channel geometry on platelet activation and blood damage.
Annals of biomedical engineering 2011;39(2):897-910.
2010: Qiufang Cheng; Erik Tucker; Meghann S Pine; India Sisler; Anton Matafonov; Mao-Fu Sun; Tara C White-Adams; Ann Stephanie Smith; Stephen R Hanson; Owen J T McCarty; Thomas Renné; András Gruber; David Gailani
A role for factor XIIa-mediated factor XI activation in thrombus formation in vivo.
Blood 2010;116(19):3981-9.
2010: David Levitz; Monica T Hinds; A Ardeshiri; Stephen R Hanson; Steven L Jacques
Non-destructive label-free monitoring of collagen gel remodeling using optical coherence tomography.
Biomaterials 2010;31(32):8210-7.
2010: Sandra Rugonyi; Erik Tucker; Ulla M Marzec; Andras Gruber; Stephen R Hanson
Transport-reaction model of mural thrombogenesis: comparisons of mathematical model predictions and results from baboon models.
Annals of biomedical engineering 2010;38(8):2660-75.
2010: Erik I Tucker; Ulla M Marzec; Michelle A Berny; Sawan Hurst; Stuart Bunting; Owen J T McCarty; Andras Gruber; Stephen R Hanson
Safety and antithrombotic efficacy of moderate platelet count reduction by thrombopoietin inhibition in primates.
Science translational medicine 2010;2(37):37ra45.
2010: David Levitz; Monica T Hinds; Niloy Choudhury; Noi T Tran; Stephen R Hanson; Steven L Jacques
Quantitative characterization of developing collagen gels using optical coherence tomography.
Journal of biomedical optics 2010;15(2):026019.
2010: Keri Vartanian; Michelle A Berny; Owen J T McCarty; Stephen R Hanson; Monica T Hinds
Cytoskeletal structure regulates endothelial cell immunogenicity independent of fluid shear stress.
American journal of physiology. Cell physiology 2010;298(2):C333-41.
2009: Keri Vartanian; Sean J Kirkpatrick; Owen J T McCarty; Tothu (Tania) Vu; Stephen R Hanson; Monica T Hinds
Distinct extracellular matrix microenvironments of progenitor and carotid endothelial cells.
Journal of biomedical materials research. Part A 2009;91(2):528-39.
2009: Erik Tucker; Ulla M Marzec; Tara White; Sawan Hurst; Sandra Rugonyi; Owen J T McCarty; David Gailani; Andras Gruber; Stephen R Hanson
Prevention of vascular graft occlusion and thrombus-associated thrombin generation by inhibition of factor XI.
Blood 2009;113(4):936-44.
2008: Monica T Hinds; MinHui Ma; Noi Tran; Ann E Ensley; Stephanie M Kladakis; Keri Vartanian; Brandon Markway; Robert M Nerem; Stephen R Hanson
Potential of baboon endothelial progenitor cells for tissue engineered vascular grafts.
Journal of biomedical materials research. Part A 2008;86(3):804-12.
2008: Erik Tucker; David Gailani; Sawan Hurst; Qiufang Cheng; Stephen R Hanson; Andras Gruber
Survival advantage of coagulation factor XI-deficient mice during peritoneal sepsis.
The Journal of infectious diseases 2008;198(2):271-4.
2008: Keri Vartanian; Sean J Kirkpatrick; Stephen R Hanson; Monica T Hinds
Endothelial cell cytoskeletal alignment independent of fluid shear stress on micropatterned surfaces.
Biochemical and biophysical research communications 2008;371(4):787-92.
2008: Kenichi A Tanaka; Andras Gruber; fania szlam; Leslie A Bush; Stephen R Hanson; Enrico Di Cera
Interaction between thrombin mutant W215A/E217A and direct thrombin inhibitor.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis 2008;19(5):465-8.
2008: Brandon Markway; Owen J T McCarty; Ulla M Marzec; David W Courtman; Stephen R Hanson; Monica T Hinds
Capture of flowing endothelial cells using surface-immobilized anti-kinase insert domain receptor antibody.
Tissue engineering. Part C, Methods 2008;14(2):97-105.
2008: Anna M Fallon; Lakshmi Prasad Dasi; Ulla M Marzec; Stephen R Hanson; Ajit P Yoganathan
Procoagulant properties of flow fields in stenotic and expansive orifices.
Annals of biomedical engineering 2008;36(1):1-13.
2007: Rehana S Lovely; Lynn K Boshkov; Ulla M Marzec; Stephen R Hanson; David H Farrell
Fibrinogen gamma' chain carboxy terminal peptide selectively inhibits the intrinsic coagulation pathway.
British journal of haematology 2007;139(3):494-503.
2007: Andras Gruber; Ulla M Marzec; Leslie Bush; Enrico Di Cera; José A Fernández; Michelle Berny; Erik Tucker; Owen J T McCarty; John H Griffin; Stephen R Hanson
Relative antithrombotic and antihemostatic effects of protein C activator versus low-molecular-weight heparin in primates.
Blood 2007;109(9):3733-40.
2007: Ruikang K Wang; Steven L Jacques; Zhenhe Ma; Sawan Hurst; Stephen R Hanson; Andras Gruber
Three dimensional optical angiography.
Optics express 2007;15(7):4083-97.
2007: Tara White; Michelle Berny; David K Robinson; Hang Yin; William F DeGrado; Stephen R Hanson; Owen J T McCarty
The leech product saratin is a potent inhibitor of platelet integrin alpha2beta1 and von Willebrand factor binding to collagen.
The FEBS journal 2007;274(6):1481-91.
2007: Sumanas W Jordan; Carolyn A Haller; Rory E Sallach; Robert P Apkarian; Stephen R Hanson; Elliot L Chaikof
The effect of a recombinant elastin-mimetic coating of an ePTFE prosthesis on acute thrombogenicity in a baboon arteriovenous shunt.
Biomaterials 2007;28(6):1191-7.
2007: Anna M Fallon; Ulla M Marzec; Stephen R Hanson; Ajit P Yoganathan
Thrombin formation in vitro in response to shear-induced activation of platelets.
Thrombosis research 2007;121(3):397-406.
2007: Andras Gruber; Stefan Carlsson; Harry F Kotzé; Ulla M Marzec; Troy C Sarich; Stephen R Hanson
Hemostatic effect of activated factor VII without promotion of thrombus growth in melagatran-anticoagulated primates.
Thrombosis research 2007;119(1):121-7.
2006: Sumanas W Jordan; Keith M Faucher; Jeffrey M Caves; Robert P Apkarian; SHYAM RELE; Xue-Long Sun; Stephen R Hanson; Elliot L Chaikof
Fabrication of a phospholipid membrane-mimetic film on the luminal surface of an ePTFE vascular graft.
Biomaterials 2006;27(18):3473-81.
2006: Wendy B Young; Joyce Mordenti; Steven Torkelson; William D Shrader; Aleksandr Kolesnikov; Roopa Rai; Liang Liu; Huiyong Hu; Ellen M Leahy; Michael J Green; Paul A Sprengeler; Bradley A Katz; Christine Yu; James W Janc; Kyle Elrod; Ulla M Marzec; Stephen R Hanson
Factor VIIa inhibitors: chemical optimization, preclinical pharmacokinetics, pharmacodynamics, and efficacy in an arterial baboon thrombosis model.
Bioorganic & medicinal chemistry letters 2006;16(7):2037-41.
2006: Anna M Fallon; Nisha Shah; Ulla M Marzec; James N Warnock; Ajit P Yoganathan; Stephen R Hanson
Flow and thrombosis at orifices simulating mechanical heart valve leakage regions.
Journal of biomechanical engineering 2006;128(1):30-9.
2006: Andras Gruber; José A Fernández; L Bush; Ulla M Marzec; John H Griffin; Stephen R Hanson; Enrico Di Cera
Limited generation of activated protein C during infusion of the protein C activator thrombin analog W215A/E217A in primates.
Journal of thrombosis and haemostasis : JTH 2006;4(2):392-7.
2006: Kenichi A Tanaka; José A Fernández; Ulla M Marzec; Andrew B Kelly; Mitsunobu Mohri; John H Griffin; Stephen R Hanson; Andras Gruber
Soluble thrombomodulin is antithrombotic in the presence of neutralising antibodies to protein C and reduces circulating activated protein C levels in primates.
British journal of haematology 2006;132(2):197-203.
2005: Alan G Olivero; Charles Eigenbrot; Richard Goldsmith; Kirk Robarge; Dean R Artis; John A Flygare; Thomas Rawson; Daniel Sutherlin; Saloumeh Kadkhodayan; Maureen H Beresini; Linda O Elliott; Geralyn G DeGuzman; David W Banner; Mark Ultsch; Ulla M Marzec; Stephen R Hanson; Canio Refino; Stuart Bunting; Daniel Kirchhofer
A selective, slow binding inhibitor of factor VIIa binds to a nonstandard active site conformation and attenuates thrombus formation in vivo.
The Journal of biological chemistry 2005;280(10):9160-9.
2005: Kenichi A Tanaka; Nobuyuki Katori; Andrew B Kelly; Harry Kotze; Ulla M Marzec; Stephen R Hanson
In vivo platelet redistribution and acute transient thrombocytopenia after eptifibatide injection in baboons.
Thrombosis research 2005;115(1-2):79-87.
2004: Peter H Lin; Changyi (Johnny) Chen; Ruth L Bush; Qizhi Yao; Alan B Lumsden; Stephen R Hanson
Small-caliber heparin-coated ePTFE grafts reduce platelet deposition and neointimal hyperplasia in a baboon model.
Journal of vascular surgery 2004;39(6):1322-8.
2003: Andras Gruber; Stephen R Hanson
Factor XI-dependence of surface- and tissue factor-initiated thrombus propagation in primates.
Blood 2003;102(3):953-5.
2003: Peter H Lin; Nicolas A F Chronos; Monique M Marijianowski; Changyi (Johnny) Chen; Brian S Conklin; Ruth L Bush; Alan B Lumsden; Stephen R Hanson
Carotid stenting using heparin-coated balloon-expandable stent reduces intimal hyperplasia in a baboon model.
The Journal of surgical research 2003;112(1):84-90.
2003: Peter H Lin; Nicolas A F Chronos; Monique M Marijianowski; Changyi (Johnny) Chen; Ruth L Bush; Brian S Conklin; Alan B Lumsden; Stephen R Hanson
Heparin-coated balloon-expandable stent reduces intimal hyperplasia in the iliac artery in baboons.
Journal of vascular and interventional radiology : JVIR 2003;14(5):603-11.
2003: K A Tanaka; J David Vega; Andrew B Kelly; Stephen R Hanson; Jerrold H Levy
Eptifibatide-induced thrombocytopenia and coronary bypass operation.
Journal of thrombosis and haemostasis : JTH 2003;1(2):392-4.
2003: Andras Gruber; Stephen R Hanson
Potential new targets for antithrombotic therapy.
Current pharmaceutical design 2003;9(28):2367-74.
2002: Xue-Long Sun; Daniel Grande; Subramanian Baskaran; Stephen R Hanson; Elliot L Chaikof
Glycosaminoglycan mimetic biomaterials. 4. Synthesis of sulfated lactose-based glycopolymers that exhibit anticoagulant activity.
Biomacromolecules 2002;3(5):1065-70.
2002: Andras Gruber; Angelene M Cantwell; Enrico Di Cera; Stephen R Hanson
The thrombin mutant W215A/E217A shows safe and potent anticoagulant and antithrombotic effects in vivo.
The Journal of biological chemistry 2002;277(31):27581-4.
2002: Dominique L Musselman; Ulla M Marzec; Madalyn Davidoff; Amita K Manatunga; Feng Gao; Andrea Reemsnyder; Sasikanth Duggirala; Hannah Larsen; Robert W Taylor; Stephen R Hanson; Charles Nemeroff
Platelet activation and secretion in patients with major depression, thoracic aortic atherosclerosis, or renal dialysis treatment.
Depression and anxiety 2002;15(3):91-101.
2001: Kjell S Sakariassen; Stephen R Hanson; Yves Cadroy
Methods and models to evaluate shear-dependent and surface reactivity-dependent antithrombotic efficacy.
Thrombosis research 2001;104(3):149-74.
2001: Brandon R Travis; Ulla M Marzec; Hwa-Liang Leo; T Momin; C Sanders; Stephen R Hanson; Ajit P Yoganathan
Bileaflet aortic valve prosthesis pivot geometry influences platelet secretion and anionic phospholipid exposure.
Annals of biomedical engineering 2001;29(8):657-64.
2001: D M Wootton; CP Markou; Stephen R Hanson; David N Ku
A mechanistic model of acute platelet accumulation in thrombogenic stenoses.
Annals of biomedical engineering 2001;29(4):321-9.
2001: CP Markou; Nicolas A F Chronos; Stephen R Hanson
Antithrombotic effects of ionic and non-ionic contrast media in nonhuman primates.
Thrombosis and haemostasis 2001;85(3):488-93.
2001: Brandon R Travis; Ulla M Marzec; JT Ellis; P Davoodi; T Momin; Stephen R Hanson; LA Harker; Ajit P Yoganathan
The sensitivity of indicators of thrombosis initiation to a bileaflet prosthesis leakage stimulus.
The Journal of heart valve disease 2001;10(2):228-38.
2000: Dominique L Musselman; Ulla M Marzec; Amita K Manatunga; Suzanne Penna; Andrea Reemsnyder; Bettina T Knight; A Baron; Stephen R Hanson; Charles Nemeroff
Platelet reactivity in depressed patients treated with paroxetine: preliminary findings.
Archives of general psychiatry 2000;57(9):875-82.
2000: D J Hayzer; M Shoji; Stephen R Hanson
cDNAs encoding the baboon thrombin receptor indicate a primate transcription start site upstream of putative sites reported for the human gene.
Thrombosis research 2000;98(2):195-201.
2000: Stefan Verheye; CP Markou; MY Salame; B Wan; Spencer B King; Keith A Robinson; Nicolas A F Chronos; Stephen R Hanson
Reduced thrombus formation by hyaluronic acid coating of endovascular devices.
Arteriosclerosis, thrombosis, and vascular biology 2000;20(4):1168-72.
2000: Changyi (Johnny) Chen; Alan B Lumsden; Stephen R Hanson
Local infusion of heparin reduces anastomotic neointimal hyperplasia in aortoiliac expanded polytetrafluoroethylene bypass grafts in baboons.
Journal of vascular surgery 2000;31(2):354-63.
1999: A Lundell; Andrew B Kelly; J Anderson; Monique M Marijianowski; Jeffrey J Rade; Stephen R Hanson; LA Harker
Reduction in vascular lesion formation by hirudin secreted from retrovirus-transduced confluent endothelial cells on vascular grafts in baboons.
Circulation 1999;100(19):2018-24.
1999: Nobuyuki Komiyama; Nicolas A F Chronos; Neal G Uren; M P Moore; Andrew B Kelly; LA Harker; Stephen R Hanson; JA Metz; Paul G Yock; Peter J Fitzgerald
The progression of thrombus in an ex-vivo shunt model evaluated by intravascular ultrasound radiofrequency analysis.
Ultrasound in medicine & biology 1999;25(4):561-6.
1999: Neill A Giese; Monique M Marijianowski; O McCook; A Hancock; V Ramakrishnan; L J Fretto; Changyi (Johnny) Chen; Andrew B Kelly; J A Koziol; Josiah N Wilcox; Stephen R Hanson
The role of alpha and beta platelet-derived growth factor receptor in the vascular response to injury in nonhuman primates.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(4):900-9.
1998: LA Harker; Ulla M Marzec; Andrew B Kelly; N R Chronos; IB Sundell; Stephen R Hanson; J M Herbert
Clopidogrel inhibition of stent, graft, and vascular thrombogenesis with antithrombotic enhancement by aspirin in nonhuman primates.
Circulation 1998;98(22):2461-9.
1998: E J Mattsson; R L Geary; Larry W Kraiss; SM Vergel; J K Liao; M A Corson; Y P Au; Stephen R Hanson; Alexander W Clowes
Is smooth muscle growth in primate arteries regulated by endothelial nitric oxide synthase?
Journal of vascular surgery 1998;28(3):514-21.
1998: Changyi (Johnny) Chen; JC Ofenloch; Y P Yianni; Stephen R Hanson; Alan B Lumsden
Phosphorylcholine coating of ePTFE reduces platelet deposition and neointimal hyperplasia in arteriovenous grafts.
The Journal of surgical research 1998;77(2):119-25.
1998: Stephen R Hanson; Kjell S Sakariassen
Blood flow and antithrombotic drug effects.
American heart journal 1998;135(5 Pt 2 Su):S132-45.
1998: CP Markou; E M Lutostansky; David N Ku; Stephen R Hanson
A novel method for efficient drug delivery.
Annals of biomedical engineering 1998;26(3):502-11.
1998: CP Markou; J E Brown; M D Pursley; Stephen R Hanson
Boundary layer drug delivery using a helical catheter.
Journal of controlled release : official journal of the Controlled Release Society 1998;53(1-3):281-8.
1998: George A Stouffer; Zhaoyong Hu; M Sajid; H Li; G Jin; M T Nakada; Stephen R Hanson; Marschall S Runge
Beta3 integrins are upregulated after vascular injury and modulate thrombospondin- and thrombin-induced proliferation of cultured smooth muscle cells.
Circulation 1998;97(9):907-15.
1998: JA Chinn; J A Sauter; R E Phillips; W J Kao; J M Anderson; Stephen R Hanson; T R Ashton
Blood and tissue compatibility of modified polyester: thrombosis, inflammation, and healing.
Journal of biomedical materials research 1998;39(1):130-40.
1997: IB Sundell; Ulla M Marzec; Andrew B Kelly; Nicolas A F Chronos; L C Petersen; Stephen R Hanson; U Hedner; LA Harker
Reduction in stent and vascular graft thrombosis and enhancement of thrombolysis by recombinant Lys-plasminogen in nonhuman primates.
Circulation 1997;96(3):941-8.
1997: Alan B Lumsden; Changyi (Johnny) Chen; JD Hughes; Andrew B Kelly; Stephen R Hanson; LA Harker
Anti-VLA-4 antibody reduces intimal hyperplasia in the endarterectomized carotid artery in nonhuman primates.
Journal of vascular surgery 1997;26(1):87-93.
1997: Johannes Ruef; Z Y Hu; Li-Yan Yin; Yaxu Wu; Stephen R Hanson; Andrew B Kelly; LA Harker; G N Rao; Marschall S Runge; Winston Patterson
Induction of vascular endothelial growth factor in balloon-injured baboon arteries. A novel role for reactive oxygen species in atherosclerosis.
Circulation research 1997;81(1):24-33.
1997: LA Harker; Stephen R Hanson; Andrew B Kelly
Antithrombotic strategies targeting thrombin activities, thrombin receptors and thrombin generation.
Thrombosis and haemostasis 1997;78(1):736-41.
1997: Changyi (Johnny) Chen; J Li; S G Mattar; G F Pierce; L Aukerman; Stephen R Hanson; Alan B Lumsden
Boundary layer infusion of basic fibroblast growth factor accelerates intimal hyperplasia in endarterectomized canine artery.
The Journal of surgical research 1997;69(2):300-6.
1997: C Bode; Stephen R Hanson; JF Schmedtje; E Haber; P Mehwald; Andrew B Kelly; LA Harker; Marschall S Runge
Antithrombotic potency of hirudin is increased in nonhuman primates by fibrin targeting.
Circulation 1997;95(4):800-4.
1997: Changyi (Johnny) Chen; Stephen R Hanson; L K Keefer; J E Saavedra; K M Davies; T C Hutsell; JD Hughes; DN Ku; Alan B Lumsden
Boundary layer infusion of nitric oxide reduces early smooth muscle cell proliferation in the endarterectomized canine artery.
The Journal of surgical research 1997;67(1):26-32.
1997: Changyi (Johnny) Chen; Alan B Lumsden; JC Ofenloch; B Noe; E J Campbell; Peter W Stratford; Y P Yianni; A S Taylor; Stephen R Hanson
Phosphorylcholine coating of ePTFE grafts reduces neointimal hyperplasia in canine model.
Annals of vascular surgery 1997;11(1):74-9.
1997: LA Harker; Ulla M Marzec; Andrew B Kelly; E Cheung; A Tomer; Janet L Nichol; Stephen R Hanson; R B Stead
Prevention of thrombocytopenia and neutropenia in a nonhuman primate model of marrow suppressive chemotherapy by combining pegylated recombinant human megakaryocyte growth and development factor and recombinant human granulocyte colony-stimulating factor.
Blood 1997;89(1):155-65.
1996: Alan B Lumsden; Changyi (Johnny) Chen; K A Coyle; JC Ofenloch; J H Wang; H K Yasuda; Stephen R Hanson
Nonporous silicone polymer coating of expanded polytetrafluoroethylene grafts reduces graft neointimal hyperplasia in dog and baboon models.
Journal of vascular surgery 1996;24(5):825-33.
1996: Joseph E Saavedra; G J Southan; K M Davies; A Lundell; C Markou; Stephen R Hanson; C Adrie; William E Hurford; Warren M Zapol; Larry K Keefer
Localizing antithrombotic and vasodilatory activity with a novel, ultrafast nitric oxide donor.
Journal of medicinal chemistry 1996;39(22):4361-5.
1996: Changyi (Johnny) Chen; S G Mattar; JD Hughes; G F Pierce; J E Cook; David N Ku; Stephen R Hanson; Alan B Lumsden
Recombinant mitotoxin basic fibroblast growth factor-saporin reduces venous anastomotic intimal hyperplasia in the arteriovenous graft.
Circulation 1996;94(8):1989-95.
1996: Marschall S Runge; L A Harker; Christoph Bode; Johannes Ruef; Andrew B Kelly; Ulla M Marzec; E Allen; R Caban; S Y Shaw; E Haber; Stephen R Hanson
Enhanced thrombolytic and antithrombotic potency of a fibrin-targeted plasminogen activator in baboons.
Circulation 1996;94(6):1412-22.
1996: LA Harker; Ulla M Marzec; P Hunt; Andrew B Kelly; A Tomer; E Cheung; Stephen R Hanson; R B Stead
Dose-response effects of pegylated human megakaryocyte growth and development factor on platelet production and function in nonhuman primates.
Blood 1996;88(2):511-21.
1996: Changyi (Johnny) Chen; JD Hughes; S G Mattar; Stephen R Hanson; Alan B Lumsden
Transgraft infusion of heparin to prevent early thrombosis of expanded PTFE grafts in canine femoral veins.
Annals of vascular surgery 1996;10(2):147-55.
1996: D J Smith; D Chakravarthy; S Pulfer; M L Simmons; Joseph A Hrabie; M L Citro; Joseph E Saavedra; K M Davies; T C Hutsell; Daniel Mooradian; Stephen R Hanson; Larry K Keefer
Nitric oxide-releasing polymers containing the [N(O)NO]- group.
Journal of medicinal chemistry 1996;39(5):1148-56.
1996: LA Harker; P Hunt; Ulla M Marzec; Andrew B Kelly; A Tomer; Stephen R Hanson; R B Stead
Regulation of platelet production and function by megakaryocyte growth and development factor in nonhuman primates.
Blood 1996;87(5):1833-44.
1996: S G Mattar; Stephen R Hanson; G F Pierce; Changyi (Johnny) Chen; JD Hughes; J E Cook; C Shen; B A Noe; C R Suwyn; June R Scott; Alan B Lumsden
Local infusion of FGF-saporin reduces intimal hyperplasia.
The Journal of surgical research 1996;60(2):339-44.
1996: D A Dichek; J Anderson; Andrew B Kelly; Stephen R Hanson; LA Harker
Enhanced in vivo antithrombotic effects of endothelial cells expressing recombinant plasminogen activators transduced with retroviral vectors.
Circulation 1996;93(2):301-9.
1996: LA Harker; Stephen R Hanson; Josiah N Wilcox; A B Kelly
Antithrombotic and antilesion benefits without hemorrhagic risks by inhibiting tissue factor pathway.
Haemostasis 1996;26 Suppl 1():76-82.
1995: G L Nunes; Clifford Thomas; Stephen R Hanson; J J Barry; Spencer B King; NA Scott
Inhibition of platelet-dependent thrombosis by local delivery of heparin with a hydrogel-coated balloon.
Circulation 1995;92(7):1697-700.
1995: M D Rand; Stephen R Hanson; Kenneth G Mann
Factor V turnover in a primate model.
Blood 1995;86(7):2616-23.
1995: Changyi (Johnny) Chen; Stephen R Hanson; Alan B Lumsden
Boundary layer infusion of heparin prevents thrombosis and reduces neointimal hyperplasia in venous polytetrafluoroethylene grafts without systemic anticoagulation.
Journal of vascular surgery 1995;22(3):237-45; discussion 246-7.
1995: T Yokoyama; Andrew B Kelly; Ulla M Marzec; Stephen R Hanson; S Kunitada; LA Harker
Antithrombotic effects of orally active synthetic antagonist of activated factor X in nonhuman primates.
Circulation 1995;92(3):485-91.
1995: LA Harker; Stephen R Hanson; Andrew B Kelly
Antithrombotic benefits and hemorrhagic risks of direct thrombin antagonists.
Thrombosis and haemostasis 1995;74(1):464-72.
1995: LA Harker; Stephen R Hanson; Marschall S Runge
Thrombin hypothesis of thrombus generation and vascular lesion formation.
The American journal of cardiology 1995;75(6):12B-17B.
1995: Stephen R Hanson; T C Hutsell; L K Keefer; Daniel Mooradian; D J Smith
Nitric oxide donors: a continuing opportunity in drug design.
Advances in pharmacology (San Diego, Calif.) 1995;34():383-98.
1994: D J Hayzer; M Shoji; T M Kim; Marschall S Runge; Stephen R Hanson
Alternative splicing of the mRNA encoding baboon glycoprotein receptor GPIIb.
Gene 1994;151(1-2):267-71.
1994: Josiah N Wilcox; J Rodriguez; R Subramanian; J Ollerenshaw; C Zhong; D J Hayzer; C Horaist; Stephen R Hanson; A Lumsden; T A Salam
Characterization of thrombin receptor expression during vascular lesion formation.
Circulation research 1994;75(6):1029-38.
1994: J M Siegel; CP Markou; David N Ku; Stephen R Hanson
A scaling law for wall shear rate through an arterial stenosis.
Journal of biomechanical engineering 1994;116(4):446-51.
1994: NA Scott; G L Nunes; Spencer B King; L A Harker; Stephen R Hanson
Local delivery of an antithrombin inhibits platelet-dependent thrombosis.
Circulation 1994;90(4):1951-5.
1994: LA Harker; Stephen R Hanson
Platelet factors predisposing to arterial thrombosis.
Baillière's clinical haematology 1994;7(3):499-522.
1994: G L Nunes; Stephen R Hanson; Spencer B King; R A Sahatjian; NA Scott
Local delivery of a synthetic antithrombin with a hydrogel-coated angioplasty balloon catheter inhibits platelet-dependent thrombosis.
Journal of the American College of Cardiology 1994;23(7):1578-83.
1994: Y Cadroy; Stephen R Hanson; Andrew B Kelly; Ulla M Marzec; B L Evatt; Thomas J Kunicki; R R Montgomery; LA Harker
Relative antithrombotic effects of monoclonal antibodies targeting different platelet glycoprotein-adhesive molecule interactions in nonhuman primates.
Blood 1994;83(11):3218-24.
1994: T A Salam; Bradley Taylor; William D Suggs; Stephen R Hanson; Alan B Lumsden
Reaction to injury following balloon angioplasty and intravascular stent placement in the canine femoral artery.
The American surgeon 1994;60(5):353-7.
1994: C M Kessler; Stephen R Hanson
Platelet thromboembolism.
European journal of clinical investigation 1994;24 Suppl 1():38-41.
1993: Eric J Heilmann; Paul Friese; S Anderson; James N George; Stephen R Hanson; SA Burstein; George L Dale
Biotinylated platelets: a new approach to the measurement of platelet life span.
British journal of haematology 1993;85(4):729-35.
1993: M Shoji; D J Hayzer; T M Kim; Marschall S Runge; Stephen R Hanson
Human and baboon integrin beta 5 subunit-encoding mRNAs have alternative polyadenylation sites.
Gene 1993;133(2):307-8.
1993: Yves Cadroy; Stephen R Hanson; L A Harker
Antithrombotic effects of synthetic pentasaccharide with high affinity for plasma antithrombin III in non-human primates.
Thrombosis and haemostasis 1993;70(4):631-5.
1993: Stephen R Hanson; J H Griffin; L A Harker; A B Kelly; C T Esmon; Andras Gruber
Antithrombotic effects of thrombin-induced activation of endogenous protein C in primates.
The Journal of clinical investigation 1993;92(4):2003-12.
1993: Yves Cadroy; Stephen R Hanson; L A Harker
Dermatan sulfate inhibition of fibrin-rich thrombus formation in nonhuman primates.
Arteriosclerosis and thrombosis : a journal of vascular biology / American Heart Association 1993;13(8):1213-7.
1993: A Bass; W C Krupski; Stephen R Hanson; T Dodson; A Lumsden; D White; L A Harker; Andrew B Kelly
Exteriorized chronic aorto-caval arteriovenous access shunts in the baboon (Papio cynocephalus).
Journal of medical primatology 1993;22(6):331-9.
1993: D J Hayzer; M Shoji; T M Kim; Marschall S Runge; Stephen R Hanson
Characterization of a cDNA encoding the beta-chain of baboon receptor glycoprotein GPIb.
Gene 1993;127(2):271-2.
1993: Alan B Lumsden; Andrew B Kelly; P A Schneider; W C Krupski; T Dodson; Stephen R Hanson; LA Harker
Lasting safe interruption of endarterectomy thrombosis by transiently infused antithrombin peptide D-Phe-Pro-ArgCH2Cl in baboons.
Blood 1993;81(7):1762-70.
1993: LA Harker; Andrew B Kelly; Stephen R Hanson; W Krupski; A Bass; B Osterud; garret fitzgerald; S H Goodnight; William E Connor
Interruption of vascular thrombus formation and vascular lesion formation by dietary n-3 fatty acids in fish oil in nonhuman primates.
Circulation 1993;87(3):1017-29.
1993: William C Krupski; A Bass; A B Kelly; Z M Ruggeri; L A Harker; Stephen R Hanson
Interruption of vascular thrombosis by bolus anti-platelet glycoprotein IIb/IIIa monoclonal antibodies in baboons.
Journal of vascular surgery 1993;17(2):294-303; discussion 303-4.
1992: W C Krupski; A Bass; Y Cadroy; Andrew B Kelly; LA Harker; Stephen R Hanson
Antihemostatic and antithrombotic effects of monoclonal antibodies against von Willebrand factor in nonhuman primates.
Surgery 1992;112(2):433-9; discussion 439-40.
1992: Andrew B Kelly; J M Maraganore; P Bourdon; Stephen R Hanson; LA Harker
Antithrombotic effects of synthetic peptides targeting various functional domains of thrombin.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(13):6040-4.
1992: C Kessler; Andrew B Kelly; William D Suggs; J D Weissman; Charles M Epstein; Stephen R Hanson; LA Harker
Induction of transient neurological dysfunction in baboons by platelet microemboli.
Stroke; a journal of cerebral circulation 1992;23(5):697-702.
1992: D Kiaei; Allan S Hoffman; Stephen R Hanson
Ex vivo and in vitro platelet adhesion on RFGD deposited polymers.
Journal of biomedical materials research 1992;26(3):357-72.
1992: Christof Kessler; Andrew B Kelly; William D Suggs; Stephen R Hanson; L A Harker
Production of transient ischaemic events by platelet emboli in baboons.
Neurological research 1992;14(2 Suppl):187-9.
1991: Andras Gruber; L A Harker; Stephen R Hanson; A B Kelly; J H Griffin
Antithrombotic effects of combining activated protein C and urokinase in nonhuman primates.
Circulation 1991;84(6):2454-62.
1991: A Tomer; Stephen R Hanson; LA Harker
Autologous platelet kinetics in patients with severe thrombocytopenia: discrimination between disorders of production and destruction.
The Journal of laboratory and clinical medicine 1991;118(6):546-54.
1991: W C Krupski; A Bass; Andrew B Kelly; Stephen R Hanson; LA Harker
Reduction in thrombus formation by placement of endovascular stents at endarterectomy sites in baboon carotid arteries.
Circulation 1991;84(4):1749-57.
1991: Stephen R Hanson; Jerry S Powell; T Dodson; A Lumsden; Andrew B Kelly; J S Anderson; A W Clowes; LA Harker
Effects of angiotensin converting enzyme inhibition with cilazapril on intimal hyperplasia in injured arteries and vascular grafts in the baboon.
Hypertension 1991;18(4 Suppl):II70-6.
1991: LA Harker; Andrew B Kelly; Stephen R Hanson
Experimental arterial thrombosis in nonhuman primates.
Circulation 1991;83(6 Suppl):IV41-55.
1991: Francisco España; Andras Gruber; Mary J Heeb; Stephen R Hanson; L A Harker; J H Griffin
In vivo and in vitro complexes of activated protein C with two inhibitors in baboons.
Blood 1991;77(8):1754-60.
1991: Andrew B Kelly; Ulla M Marzec; W Krupski; A Bass; Y Cadroy; Stephen R Hanson; LA Harker
Hirudin interruption of heparin-resistant arterial thrombus formation in baboons.
Blood 1991;77(5):1006-12.
1991: Y Cadroy; J M Maraganore; Stephen R Hanson; LA Harker
Selective inhibition by a synthetic hirudin peptide of fibrin-dependent thrombosis in baboons.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(4):1177-81.
1991: Stephen R Hanson
Inhibition of platelet function in a baboon thrombosis model.
Current studies in hematology and blood transfusion 1991;(58):37-41.
1990: Stephen R Hanson; Harry F Kotzé; H Pieters; A D Heyns
Analysis of indium-111 platelet kinetics and imaging in patients with aortic grafts and abdominal aortic aneurysms.
Arteriosclerosis (Dallas, Tex.) 1990;10(6):1037-44.
1990: Andras Gruber; Stephen R Hanson; A B Kelly; B S Yan; N Bang; John H Griffin; L A Harker
Inhibition of thrombus formation by activated recombinant protein C in a primate model of arterial thrombosis.
Circulation 1990;82(2):578-85.
1990: W C Krpski; A Bass; Andrew B Kelly; Ulla M Marzec; Stephen R Hanson; L A Harker
Heparin-resistant thrombus formation by endovascular stents in baboons. Interruption by a synthetic antithrombin.
Circulation 1990;82(2):570-7.
1990: M A Golden; Stephen R Hanson; T R Kirkman; P A Schneider; Alexander W Clowes
Healing of polytetrafluoroethylene arterial grafts is influenced by graft porosity.
Journal of vascular surgery 1990;11(6):838-44; discussion 845.
1990: Y Cadroy; Stephen R Hanson
Effects of red blood cell concentration on hemostasis and thrombus formation in a primate model.
Blood 1990;75(11):2185-93.
1990: A Bass; A B Kelly; S M Otis; Stephen R Hanson; A Torruella; L A Harker; W C Krupski
Duplex ultrasound analysis of operated carotid arteries in baboons.
Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine 1990;9(5):267-73.
1990: Ulla M Marzec; Andrew B Kelly; Stephen R Hanson; A Lasslo; L A Harker
Inhibition of thrombus formation in vivo by novel antiplatelet agent.
Arteriosclerosis (Dallas, Tex.) 1990;10(3):367-71.
1990: P A Schneider; Stephen R Hanson; T M Price; L A Harker
Confluent durable endothelialization of endarterectomized baboon aorta by early attachment of cultured endothelial cells.
Journal of vascular surgery 1990;11(3):365-72.
1989: A B Kelly; Stephen R Hanson; L W Henderson; L A Harker
Prevention of heparin-resistant thrombotic occlusion of hollow-fiber hemodialyzers by synthetic antithrombin.
The Journal of laboratory and clinical medicine 1989;114(4):411-8.
1989: Y Cadroy; L A Harker; Stephen R Hanson
Inhibition of platelet-dependent thrombosis by low molecular weight heparin (CY222): comparison with standard heparin.
The Journal of laboratory and clinical medicine 1989;114(4):349-57.
1989: Y Cadroy; R A Houghten; Stephen R Hanson
RGDV peptide selectively inhibits platelet-dependent thrombus formation in vivo. Studies using a baboon model.
The Journal of clinical investigation 1989;84(3):939-44.
1989: Brian Savage; C S Hunter; L A Harker; V L Woods; Stephen R Hanson
Thrombin-induced increase in surface expression of epitopes on platelet membrane glycoprotein IIb/IIIa complex and GMP-140 is a function of platelet age.
Blood 1989;74(3):1007-14.
1989: P A Schneider; Harry F Kotzé; A D Heyns; Stephen R Hanson
Thromboembolic potential of synthetic vascular grafts in baboons.
Journal of vascular surgery 1989;10(1):75-82.
1989: Y Cadroy; T A Horbett; Stephen R Hanson
Discrimination between platelet-mediated and coagulation-mediated mechanisms in a model of complex thrombus formation in vivo.
The Journal of laboratory and clinical medicine 1989;113(4):436-48.
1989: Andras Gruber; John H Griffin; L A Harker; Stephen R Hanson
Inhibition of platelet-dependent thrombus formation by human activated protein C in a primate model.
Blood 1989;73(3):639-42.
1988: S Torem; P A Schneider; L D Paxton; H Yasuda; Stephen R Hanson
Factors influencing acute thrombus formation on carotid artery vascular grafts.
ASAIO transactions / American Society for Artificial Internal Organs 1988;34(4):916-20.
1988: Y S Yeh; Y Iriyama; Y Matsuzawa; Stephen R Hanson; Hirotsugu Yasuda
Blood compatibility of surfaces modified by plasma polymerization.
Journal of biomedical materials research 1988;22(9):795-818.
1988: P A Schneider; Stephen R Hanson; T M Price; L A Harker
Preformed confluent endothelial cell monolayers prevent early platelet deposition on vascular prostheses in baboons.
Journal of vascular surgery 1988;8(3):229-35.
1988: Stephen R Hanson; L A Harker
Interruption of acute platelet-dependent thrombosis by the synthetic antithrombin D-phenylalanyl-L-prolyl-L-arginyl chloromethyl ketone.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(9):3184-8.
1988: P A Schneider; Stephen R Hanson; T M Price; L A Harker
Durability of confluent endothelial cell monolayers on small-caliber vascular prostheses in vitro.
Surgery 1988;103(4):456-62.
1988: S Torem; P A Schneider; Stephen R Hanson
Monoclonal antibody-induced inhibition of platelet function: effects on hemostasis and vascular graft thrombosis in baboons.
Journal of vascular surgery 1988;7(1):172-80.
1988: Brian Savage; Stephen R Hanson; L A Harker
Selective decrease in platelet dense granule adenine nucleotides during recovery from acute experimental thrombocytopenia and ensuing thrombocytosis in baboons.
British journal of haematology 1988;68(1):75-82.
1988: Stephen R Hanson; F I Pareti; Zaverio M Ruggeri; Ulla M Marzec; Thomas J Kunicki; R R Montgomery; T S Zimmerman; L A Harker
Effects of monoclonal antibodies against the platelet glycoprotein IIb/IIIa complex on thrombosis and hemostasis in the baboon.
The Journal of clinical investigation 1988;81(1):149-58.
1987: T D Bjornsson; Stephen R Hanson; L A Harker
Effective antiplatelet drug concentrations in experimental arterial thromboembolism.
Thrombosis research 1987;48(3):337-48.
1987: Stephen R Hanson; L A Harker
Baboon models of acute arterial thrombosis.
Thrombosis and haemostasis 1987;58(3):801-5.
1987: J S Anderson; T M Price; Stephen R Hanson; L A Harker
In vitro endothelialization of small-caliber vascular grafts.
Surgery 1987;101(5):577-86.
1987: Stephen R Hanson; L A Harker
Vascular graft thrombus formation.
Annals of the New York Academy of Sciences 1987;516():653-61.
1986: Gregory J del Zoppo; B R Copeland; L A Harker; T A Waltz; Jack Zyroff; Stephen R Hanson; E Battenberg
Experimental acute thrombotic stroke in baboons.
Stroke; a journal of cerebral circulation 1986;17(6):1254-65.
1986: Stephen R Hanson; L D Paxton; L A Harker
Iliac artery mural thrombus formation. Effect of antiplatelet therapy on 111In-platelet deposition in baboons.
Arteriosclerosis (Dallas, Tex.) 1986;6(5):511-8.
1986: Brian Savage; P R McFadden; Stephen R Hanson; L A Harker
The relation of platelet density to platelet age: survival of low- and high-density 111indium-labeled platelets in baboons.
Blood 1986;68(2):386-93.
1986: Thomas A Horbett; C M Cheng; Buddy Ratner; Allan S Hoffman; Stephen R Hanson
The kinetics of baboon fibrinogen adsorption to polymers: in vitro and in vivo studies.
Journal of biomedical materials research 1986;20(6):739-72.
1985: Stephen R Hanson; S J Slichter
Platelet kinetics in patients with bone marrow hypoplasia: evidence for a fixed platelet requirement.
Blood 1985;66(5):1105-9.
1985: Stephen R Hanson; H F Kotze; Brian Savage; L A Harker
Platelet interactions with Dacron vascular grafts. A model of acute thrombosis in baboons.
Arteriosclerosis (Dallas, Tex.) 1985;5(6):595-603.
1985: Stephen R Hanson; L A Harker
Studies of suloctidil in experimental thrombosis in baboons.
Thrombosis and haemostasis 1985;53(3):423-7.
1985: Stephen R Hanson; L A Harker; T D Bjornsson
Effects of platelet-modifying drugs on arterial thromboembolism in baboons. Aspirin potentiates the antithrombotic actions of dipyridamole and sulfinpyrazone by mechanism(s) independent of platelet cyclooxygenase inhibition.
The Journal of clinical investigation 1985;75(5):1591-9.
1985: A W Clowes; A M Gown; Stephen R Hanson; M A Reidy
Mechanisms of arterial graft failure. 1. Role of cellular proliferation in early healing of PTFE prostheses.
The American journal of pathology 1985;118(1):43-54.
1984: T W Malpass; B Savage; Stephen R Hanson; S J Slichter; L A Harker
Correlation between prolonged bleeding time and depletion of platelet dense granule ADP in patients with myelodysplastic and myeloproliferative disorders.
The Journal of laboratory and clinical medicine 1984;103(6):894-904.
1984: S S Tynan; Niels H Andersen; M T Wills; L A Harker; Stephen R Hanson
On the multiplicity of platelet prostaglandin receptors. II. The use of N-0164 for distinguishing the loci of action for PGI2, PGD2, PGE2 and hydantoin analogs.
Prostaglandins 1984;27(5):683-96.
1984: A M Garfinkle; A S Hoffman; Buddy Ratner; L O Reynolds; Stephen R Hanson
Effects of a tetrafluoroethylene glow discharge on patency of small diameter dacron vascular grafts.
Transactions - American Society for Artificial Internal Organs 1984;30():432-9.
1983: Stephen R Hanson; L A Harker
Effect of dazoxiben on arterial graft thrombosis in the baboon.
British journal of clinical pharmacology 1983;15 Suppl 1():57S-60S.
1983: Stephen R Hanson; L A Harker
Ex vivo and in vivo evaluation of drugs that inhibit platelet function.
Annals of the New York Academy of Sciences 1983;416():642-50.
1982: Stephen R Hanson; M A Reidy; A Hattori; L A Harker
Pharmacologic modification of acute vascular graft thrombosis.
Scanning electron microscopy 1982;(Pt 2):773-9.
1981: Stephen R Hanson; L A Harker
Survival of baboon platelets labeled with diazotized (125-1)-iodosulfanilic acid: no effect of drugs that modify platelet behavior.
Thrombosis research 1981;23(1-2):133-43.
1981: T W Malpass; Stephen R Hanson; B Savage; E A Hessel; L A Harker
Prevention of acquired transient defect in platelet plug formation by infused prostacyclin.
Blood 1981;57(4):736-40.
1981: J D Andrade; D L Coleman; P Didisheim; Stephen R Hanson; R Mason; E Merrill
Panel conference. Blood-materials interactions - 20 years of frustration.
Transactions - American Society for Artificial Internal Organs 1981;27():659-62.
1980: Stephen R Hanson; L A Harker; Buddy Ratner; A S Hoffman
In vivo evaluation of artificial surfaces with a nonhuman primate model of arterial thrombosis.
The Journal of laboratory and clinical medicine 1980;95(2):289-304.
1979: L A Harker; Stephen R Hanson
Experimental arterial thromboembolism in baboons. Mechanism, quantitation, and pharmacologic prevention.
The Journal of clinical investigation 1979;64(2):559-60.
1979: Stephen R Hanson; L A Harker; Buddy Ratner; A S Hoffman
Factors influencing platelet consumption by polyacrylamide hydrogels.
Annals of biomedical engineering 1979;7(3-4):357-67.