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Lumír Hanus

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Chemicals & Drugs

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Brain Chemistry

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All Publications

2010: Lumír O Hanus; Urij Rampampam
Novel natural and synthetic ligands of the endocannabinoid system.
Current medicinal chemistry 2010;17(14):1341-59.
2009: Lumír O Hanus
Pharmacological and therapeutic secrets of plant and brain (endo)cannabinoids.
Medicinal research reviews 2009;29(2):213-71.
2008: Valery M Dembitsky; I Shkrob; Lumír O Hanus
Ascaridole and related peroxides from the genus Chenopodium.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2008;152(2):209-15.
2008: Lumír O Hanus; Marina Temina; Valery M Dembitsky
Biodiversity of the chemical constituents in the epiphytic lichenized ascomycete Ramalina lacera grown on difference substrates Crataegus sinaicus, Pinus halepensis, and Quercus calliprinos.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2008;152(2):203-8.
2008: Lumír O Hanus; Paulina Goldshlag; Valery M Dembitsky
Identification of cyclopropyl fatty acids in walnut (Juglans regia L.) oil.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2008;152(1):41-5.
2008: Saleh Abu-Lafi; Imad Odeh; Hasan Dewik; Mohammed Qabajah; Lumír O Hanus; Valery M Dembitsky
Thymol and carvacrol production from leaves of wild Palestinian Majorana syriaca.
Bioresource technology 2008;99(9):3914-8.
2007: Lumír O Hanus
Discovery and isolation of anandamide and other endocannabinoids.
Chemistry & biodiversity 2007;4(8):1828-41.
2007: Urij Rampampam; Maximilian Peters; Eric Murillo-Rodriguez; Lumír O Hanus
Cannabidiol--recent advances.
Chemistry & biodiversity 2007;4(8):1678-92.
2007: Saleh Abu-Lafi; Imad Odeh; Hasan Dewik; Mohammed Qabajah; Amin Imam; Valery M Dembitsky; Lumír O Hanus
Natural compounds of Palestine flora. Comparison analysis by static headspace and steam distillation GC-MS of semivolatile secondary metabolites from leaves of cultivated Palestinian Majorana syriaca.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2007;151(1):21-9.
2006: Shimon Ben-Shabat; Lumír O Hanus; Galia Katzavian; Ruth Gallily
New cannabidiol derivatives: synthesis, binding to cannabinoid receptor, and evaluation of their antiinflammatory activity.
Journal of medicinal chemistry 2006;49(3):1113-7.
2005: Lumír O Hanus; Tomás Rezanka; Jaroslav Spízek; Valery M Dembitsky
Substances isolated from Mandragora species.
Phytochemistry 2005;66(20):2408-17.
2005: Lumír O Hanus; Tomás Rezanka; Valery M Dembitsky; Arieh Moussaieff
Myrrh--Commiphora chemistry.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005;149(1):3-27.
2005: Ester Fride; Datta E Ponde; Aviva Breuer; Lumír O Hanus
Peripheral, but not central effects of cannabidiol derivatives: mediation by CB(1) and unidentified receptors.
Neuropharmacology 2005;48(8):1117-29.
2005: Valery M Dembitsky; Tomás Rezanka; Jaroslav Spízek; Lumír O Hanus
Secondary metabolites of slime molds (myxomycetes).
Phytochemistry 2005;66(7):747-69.
2005: Lumír O Hanus; Susanna Tchilibon; Datta E Ponde; Aviva Breuer; Ester Fride; Urij Rampampam
Enantiomeric cannabidiol derivatives: synthesis and binding to cannabinoid receptors.
Organic & biomolecular chemistry 2005;3(6):1116-23.
2004: Ester Fride; Cfir Feigin; Datta E Ponde; Aviva Breuer; Lumír O Hanus; Nina Arshavsky; Urij Rampampam
(+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only.
European journal of pharmacology 2004;506(2):179-88.
2004: Tomás Rezanka; Marina Temina; Lumír O Hanus; Valery M Dembitsky
The tornabeatins, four tetrahydro-2-furanone derivatives from the lichenized ascomycete Tornabea scutellifera (With.) J.R. Laundon.
Phytochemistry 2004;65(18):2605-12.
2004: Tomás Rezanka; Radmila Dvoráková; Lumír O Hanus; Valery M Dembitsky
Enteridinines A and B from slime mold Enteridium lycoperdon.
Phytochemistry 2004;65(4):455-62.
2003: Lumír O Hanus; Yosefa Avraham; Dikla Ben shushan; Olga Zolotarev; Elliot M Berry; Urij Rampampam
Short-term fasting and prolonged semistarvation have opposite effects on 2-AG levels in mouse brain.
Brain research 2003;983(1-2):144-51.
2003: Tomás Rezanka; Valery M Dembitsky; Lumír O Hanus
Two cyclohexenone glycosides from the North American fern Woodwardia virginica (L.) Smith.
Phytochemistry 2003;63(8):931-7.
2003: Lumír O Hanus; Tomás Rezanka; Valery M Dembitsky
A trinorsesterterpene glycoside from the North American fern Woodwardia virginica (L.) Smith.
Phytochemistry 2003;63(8):869-75.
2003: Tomás Rezanka; Valery M Dembitsky; J V Go; Inka Dor; A Prell; Lumír O Hanus
Sterol compositions of the filamentous nitrogen-fixing terrestrial cyanobacterium Scytonema sp.
Folia microbiologica 2003;48(3):357-60.
2002: Urij Rampampam; Lumír O Hanus
Cannabidiol: an overview of some chemical and pharmacological aspects. Part I: chemical aspects.
Chemistry and physics of lipids 2002;121(1-2):35-43.
2001: David Panikashvili; Constantina Simeonidou; Shimon Ben-Shabat; Lumír O Hanus; Aviva Breuer; Urij Rampampam; Esther Shohami
An endogenous cannabinoid (2-AG) is neuroprotective after brain injury.
Nature 2001;413(6855):527-31.
2001: Tiziana Bisogno; Lumír O Hanus; Luciano De Petrocellis; Susanna Tchilibon; Datta E Ponde; Ines Brandi; Aniello Schiano Moriello; John B Davis; Urij Rampampam; Vincenzo Di Marzo
Molecular targets for cannabidiol and its synthetic analogues: effect on vanilloid VR1 receptors and on the cellular uptake and enzymatic hydrolysis of anandamide.
British journal of pharmacology 2001;134(4):845-52.
2001: Lumír O Hanus; Saleh Abu-Lafi; Ester Fride; Aviva Breuer; zvi vogel; Deborah E Shalev; Irina Kustanovich; Urij Rampampam
2-arachidonyl glyceryl ether, an endogenous agonist of the cannabinoid CB1 receptor.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3662-5.
2000: Urij Rampampam; Lumír O Hanus
A historical overview of chemical research on cannabinoids.
Chemistry and physics of lipids 2000;108(1-2):1-13.
1999: Lumír O Hanus; Aviva Breuer; Susanna Tchilibon; S Shiloah; D Goldenberg; Michal Horowitz; R G Pertwee; R A Ross; Urij Rampampam; Ester Fride
HU-308: a specific agonist for CB(2), a peripheral cannabinoid receptor.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14228-33.
1998: Urij Rampampam; Lumír O Hanus; Ester Fride
Towards cannabinoid drugs--revisited.
Progress in medicinal chemistry 1998;35():199-243.
1997: MH Rhee; zvi vogel; Jacob Barg; Michael Bayewitch; R Levy; Lumír O Hanus; Aviva Breuer; Urij Rampampam
Cannabinol derivatives: binding to cannabinoid receptors and inhibition of adenylylcyclase.
Journal of medicinal chemistry 1997;40(20):3228-33.
1997: Urij Rampampam; Ester Fride; Lumír O Hanus; Tzviel Sheskin; T Bisogno; Vincenzo Di Marzo; Michael Bayewitch; zvi vogel
Anandamide may mediate sleep induction.
Nature 1997;389(6646):25-6.
1997: Tzviel Sheskin; Lumír O Hanus; Joram Slager; zvi vogel; Urij Rampampam
Structural requirements for binding of anandamide-type compounds to the brain cannabinoid receptor.
Journal of medicinal chemistry 1997;40(5):659-67.
1996: Urij Rampampam; Shimon Ben-Shabat; Lumír O Hanus; Ester Fride; zvi vogel; Michael Bayewitch; A E Sulcova
Endogenous cannabinoid ligands--chemical and biological studies.
Journal of lipid mediators and cell signalling 1996;14(1-3):45-9.
1996: Urij Rampampam; S B Shabat; Lumír O Hanus; Ester Fride; Michael Bayewitch; zvi vogel
Endogenous cannabinoid ligands.
Advances in experimental medicine and biology 1996;402():95-101.
1995: Jacob Barg; Ester Fride; Lumír O Hanus; R Levy; N Matus-Leibovitch; E Heldman; Michael Bayewitch; Urij Rampampam; zvi vogel
Cannabinomimetic behavioral effects of and adenylate cyclase inhibition by two new endogenous anandamides.
European journal of pharmacology 1995;287(2):145-52.
1995: Urij Rampampam; Shimon Ben-Shabat; Lumír O Hanus; M Ligumsky; Norbert E Kaminski; A R Schatz; A Gopher; S Almog; Billy R Martin; D R Compton
Identification of an endogenous 2-monoglyceride, present in canine gut, that binds to cannabinoid receptors.
Biochemical pharmacology 1995;50(1):83-90.
1994: Urij Rampampam; Lumír O Hanus; Billy R Martin
Search for endogenous ligands of the cannabinoid receptor.
Biochemical pharmacology 1994;48(8):1537-44.
1994: Roger G Pertwee; Graeme Griffin; Lumír O Hanus; Urij Rampampam
Effects of two endogenous fatty acid ethanolamides on mouse vasa deferentia.
European journal of pharmacology 1994;259(2):115-20.
1993: Lumír O Hanus; A Gopher; S Almog; Urij Rampampam
Two new unsaturated fatty acid ethanolamides in brain that bind to the cannabinoid receptor.
Journal of medicinal chemistry 1993;36(20):3032-4.
1992: W A Devane; Lumír O Hanus; Aviva Breuer; Roger G Pertwee; Lesley A Stevenson; Graeme Griffin; D Gibson; A Mandelbaum; A Etinger; Urij Rampampam
Isolation and structure of a brain constituent that binds to the cannabinoid receptor.
Science (New York, N.Y.) 1992;258(5090):1946-9.