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Gerhard Hapfelmeier

Research Profile

Chemicals & Drugs

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Patch-Clamp Techniques

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Shahnaz Christina Azad; Matthias Eder; Wanda Simon; Gerhard Hapfelmeier; Hans-Ulrich Dodt; Walter Zieglgänsberger; Gerhard Rammes
The potassium channel modulator flupirtine shifts the frequency-response function of hippocampal synapses to favour LTD in mice.
Andreas Ranft; Jörg Kurz; Martin Deuringer; Rainer Haseneder; Hans-Ulrich Dodt; Walter Zieglgänsberger; Eberhard Kochs; Matthias Eder; Gerhard Hapfelmeier
Isoflurane modulates glutamatergic and GABAergic neurotransmission in the amygdala.
Gerhard Rammes; Brigitte Eisensamer; U Ferrari; M Shapa; Gerald Gimpl; K Gilling; C Parsons; K Riering; Gerhard Hapfelmeier; B Bondy; Walter Zieglgänsberger; Florian Holsboer; Rainer Rupprecht
Antipsychotic drugs antagonize human serotonin type 3 receptor currents in a noncompetitive manner.

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2004: Shahnaz Christina Azad; Matthias Eder; Wanda Simon; Gerhard Hapfelmeier; Hans-Ulrich Dodt; Walter Zieglgänsberger; Gerhard Rammes
The potassium channel modulator flupirtine shifts the frequency-response function of hippocampal synapses to favour LTD in mice.
Neuroscience letters 2004;370(2-3):186-90.
2004: Andreas Ranft; Jörg Kurz; Martin Deuringer; Rainer Haseneder; Hans-Ulrich Dodt; Walter Zieglgänsberger; Eberhard Kochs; Matthias Eder; Gerhard Hapfelmeier
Isoflurane modulates glutamatergic and GABAergic neurotransmission in the amygdala.
The European journal of neuroscience 2004;20(5):1276-80.
2004: Gerhard Rammes; Brigitte Eisensamer; U Ferrari; M Shapa; Gerald Gimpl; K Gilling; C Parsons; K Riering; Gerhard Hapfelmeier; B Bondy; Walter Zieglgänsberger; Florian Holsboer; Rainer Rupprecht
Antipsychotic drugs antagonize human serotonin type 3 receptor currents in a noncompetitive manner.
Molecular psychiatry 2004;9(9):846-58, 818.
2004: Rainer Haseneder; Jörg Kurz; Hans-Ulrich Dodt; Eberhard Kochs; Walter Zieglgänsberger; Michaela Scheller; Gerhard Rammes; Gerhard Hapfelmeier
Isoflurane reduces glutamatergic transmission in neurons in the spinal cord superficial dorsal horn: evidence for a presynaptic site of an analgesic action.
Anesthesia and analgesia 2004;98(6):1718-23, table of contents.
2004: Tobias Deiml; Rainer Haseneder; Walter Zieglgänsberger; Gerhard Rammes; Brigitte Eisensamer; Rainer Rupprecht; Gerhard Hapfelmeier
Alpha-thujone reduces 5-HT3 receptor activity by an effect on the agonist-reduced desensitization.
Neuropharmacology 2004;46(2):192-201.
2003: Brigitte Eisensamer; Gerhard Rammes; Gerald Gimpl; M Shapa; U Ferrari; Gerhard Hapfelmeier; B Bondy; C Parsons; K Gilling; Walter Zieglgänsberger; Florian Holsboer; Rainer Rupprecht
Antidepressants are functional antagonists at the serotonin type 3 (5-HT3) receptor.
Molecular psychiatry 2003;8(12):994-1007.
2003: F DeBock; Jörg Kurz; Shahnaz Christina Azad; Christopher G Parsons; Gerhard Hapfelmeier; Walter Zieglgänsberger; Gerhard Rammes
Alpha2-adrenoreceptor activation inhibits LTP and LTD in the basolateral amygdala: involvement of Gi/o-protein-mediated modulation of Ca2+-channels and inwardly rectifying K+-channels in LTD.
The European journal of neuroscience 2003;17(7):1411-24.
2003: Gerhard Hapfelmeier; C Tredt; Rainer Haseneder; Walter Zieglgänsberger; Brigitte Eisensamer; Rainer Rupprecht; Gerhard Rammes
Co-expression of the 5-HT3B serotonin receptor subunit alters the biophysics of the 5-HT3 receptor.
Biophysical journal 2003;84(3):1720-33.
2002: Gerhard Hapfelmeier; Rainer Haseneder; Katrin Lampadius; Gerhard Rammes; Rainer Rupprecht; Walter Zieglgänsberger
Cloned human and murine serotonin(3A) receptors expressed in human embryonic kidney 293 cells display different single-channel kinetics.
Neuroscience letters 2002;335(1):44-8.
2002: Rainer Haseneder; Gerhard Rammes; Walter Zieglgänsberger; Eberhard Kochs; Gerhard Hapfelmeier
GABA(A) receptor activation and open-channel block by volatile anaesthetics: a new principle of receptor modulation?
European journal of pharmacology 2002;451(1):43-50.
2002: Robert Zanner; Gerhard Hapfelmeier; Manfred Gratzl; Christian Prinz
Intracellular signal transduction during gastrin-induced histamine secretion in rat gastric ECL cells.
American journal of physiology. Cell physiology 2002;282(2):C374-82.
2001: Gerhard Hapfelmeier; Rainer Haseneder; Matthias Eder; Helmuth Adelsberger; Eberhard Kochs; Gerhard Rammes; Walter Zieglgänsberger
Isoflurane slows inactivation kinetics of rat recombinant alpha1beta2gamma2L GABA(A) receptors: enhancement of GABAergic transmission despite an open-channel block.
Neuroscience letters 2001;307(2):97-100.
2001: Gerhard Hapfelmeier; Rainer Haseneder; Eberhard Kochs; M Beyerle; Walter Zieglgänsberger
Coadministered nitrous oxide enhances the effect of isoflurane on GABAergic transmission by an increase in open-channel block.
The Journal of pharmacology and experimental therapeutics 2001;298(1):201-8.
2001: W Simon; Gerhard Hapfelmeier; Eberhard Kochs; Walter Zieglgänsberger; Gerhard Rammes
Isoflurane blocks synaptic plasticity in the mouse hippocampus.
Anesthesiology 2001;94(6):1058-65.
2001: Gerhard Hapfelmeier; HJ Schneck; Eberhard Kochs
Sevoflurane potentiates and blocks GABA-induced currents through recombinant alpha1beta2gamma2 GABAA receptors: implications for an enhanced GABAergic transmission.
European journal of anaesthesiology 2001;18(6):377-83.
2000: Gerhard Hapfelmeier; Walter Zieglgänsberger; Rainer Haseneder; HJ Schneck; Eberhard Kochs
Nitrous oxide and xenon increase the efficacy of GABA at recombinant mammalian GABA(A) receptors.
Anesthesia and analgesia 2000;91(6):1542-9.
2000: Gerhard Hapfelmeier; Rainer Haseneder; HJ Schneck; Eberhard Kochs
[Patch clamp studies on recombinant GABA A receptors using an ultra-quick application system].
Anästhesiologie, Intensivmedizin, Notfallmedizin, Schmerztherapie : AINS 2000;35(9):601-3.
2000: S Neumahr; Gerhard Hapfelmeier; Michaela Scheller; HJ Schneck; C Franke; Eberhard Kochs
Dual action of isoflurane on the gamma-aminobutyric acid (GABA)-mediated currents through recombinant alpha(1)beta(2)gamma(2L)-GABA(A)-receptor channels.
Anesthesia and analgesia 2000;90(5):1184-90.
1999: Nina Hrboticky; G Draude; Gerhard Hapfelmeier; R Lorenz; Peter C Weber
Lovastatin decreases the receptor-mediated degradation of acetylated and oxidized LDLs in human blood monocytes during the early stage of differentiation into macrophages.
Arteriosclerosis, thrombosis, and vascular biology 1999;19(5):1267-75.
1997: R Scheithe; A K Heidenthal; U Danesch; E Mauthner; Gerhard Hapfelmeier; A Becker; A Pietsch; Peter C Weber; Nina Hrboticky
Acetylated LDL endocytosis by the human monocytic Mono Mac 6sr cells is not mediated by the macrophage type I and II scavenger receptors.
Arteriosclerosis, thrombosis, and vascular biology 1997;17(6):1024-31.