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Rudolf Happle

Research Profile

Disorders

Anatomy

Procedures

Diagnosis, Differential

Physiology

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TOP 3
Dorothea Bornholdt; Bakar Bouadjar; Benoit Catteau; Helen Cox; Deepthi De Silva; Judith Fischer; T Prescott Atkinson; Chalukya N Gunasekera; Smaïl Hadj-Rabia; Rudolf Happle; Muriel Holder-Espinasse; Elke Kaminski; Arne König; André Mégarbané; Hala Mégarbané; Ulrike Neidel; Frank Oeffner; Vinzenz Oji; Amy Theos; Heiko Traupe; Anders Vahlquist; Bregje W van Bon; Marie Virtanen; Karl-Heinz Grzeschik
Genotype-phenotype correlations emerging from the identification of missense mutations in MBTPS2.
L Groesser; Rudolf Happle; E Herschberger; Michael Landthaler; M Mickler; Thomas Vogt; Christian Hafner
Naevus marginatus revisited: a combined organoid and nonorganoid epidermal naevus caused by HRAS mutation.
Rudolf Happle
Nevus sebaceus is a mosaic RASopathy.

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2013: Dorothea Bornholdt; Bakar Bouadjar; Benoit Catteau; Helen Cox; Deepthi De Silva; Judith Fischer; T Prescott Atkinson; Chalukya N Gunasekera; Smaïl Hadj-Rabia; Rudolf Happle; Muriel Holder-Espinasse; Elke Kaminski; Arne König; André Mégarbané; Hala Mégarbané; Ulrike Neidel; Frank Oeffner; Vinzenz Oji; Amy Theos; Heiko Traupe; Anders Vahlquist; Bregje W van Bon; Marie Virtanen; Karl-Heinz Grzeschik
Genotype-phenotype correlations emerging from the identification of missense mutations in MBTPS2.
Human mutation 2013;34(4):587-94.
2013: L Groesser; Rudolf Happle; E Herschberger; Michael Landthaler; M Mickler; Thomas Vogt; Christian Hafner
Naevus marginatus revisited: a combined organoid and nonorganoid epidermal naevus caused by HRAS mutation.
The British journal of dermatology 2013;168(4):892-4.
2013: Rudolf Happle
Nevus sebaceus is a mosaic RASopathy.
The Journal of investigative dermatology 2013;133(3):597-600.
2012: Nadine Schwarz; Volker Stadie; Rudolf Happle; Burkhard Kreft; Wolfgang Ch Marsch; Eckhard Fiedler
Systematized linear porokeratosis: Concept of type 2 segmental manifestation implies an increased cancer risk.
The Journal of dermatology 2012;39(11):953-4.
2012: Jennifer A Easton; Rudolf Happle; René Janssens; Miriam A F Kamps; Patricia E Martin; Peter M Steijlen; Gianluca Tadini; Michel van Geel; Steven Donnelly; Maurice A M van Steensel
Porokeratotic eccrine nevus may be caused by somatic connexin26 mutations.
The Journal of investigative dermatology 2012;132(9):2184-91.
2012: Andreas W Arnold; Leena Bruckner-Tuderman; Rudolf Happle; Cristina Has; Ingrid Hausser; Dimitra Kiritsi; Juergen Kohlhase; Peter H Itin
Type 1 segmental Galli-Galli disease resulting from a previously unreported keratin 5 mutation.
The Journal of investigative dermatology 2012;132(8):2100-3.
2012: Andreas W Arnold; Marion U Kleine; Rudolf Happle
Phacomatosis melanorosea without extracutaneous features: an unusual type of phacomatosis pigmentovascularis.
European journal of dermatology : EJD 2012;22(4):473-5.
2012: Rudolf Happle; Ana I Nuñez-Giralda
Superimposed lateralized exanthema of childhood: a proposed explanation for an enigmatic disorder.
European journal of dermatology : EJD 2012;22(4):542-4.
2012: Rudolf Happle
Hornstein-Birt-Hogg-Dubé syndrome: a renaming and reconsideration.
American journal of medical genetics. Part A 2012;158A(6):1247-51.
2012: A W Arnold; Leena Bruckner-Tuderman; Cristina Has; Rudolf Happle
Conradi-Hünermann-Happle syndrome in males vs. MEND syndrome (male EBP disorder with neurological defects).
The British journal of dermatology 2012;166(6):1309-13.
2012: Rudolf Happle
Superimposed segmental vitiligo should not be categorized as "type 2 mosaicism".
Journal of the American Academy of Dermatology 2012;66(5):852.
2012: Dimitra Kiritsi; Meltem Onder; Anna M G Pasmooij; Leena Bruckner-Tuderman; Rudolf Happle; Yinghong He; Marcel F Jonkman; Cristina Has
Revertant mosaicism in a human skin fragility disorder results from slipped mispairing and mitotic recombination.
The Journal of clinical investigation 2012;122(5):1742-6.
2012: Antonio Torrelo; Sergio Vañó-Galván; Daniel Azorín; Christine Bodemer; Isabel Colmenero; Javier Enríquez De Salamanca; Joan C Ferreres; Vicente García-Patos; Smail Hadj-Rabia; Rudolf Happle; Angela Hernández-Martín; Helena Hilari-Carbonell; Robert Piston; Luis Requena; Virginia P Sybert; Sylvie Fraitag
Folliculocystic and collagen hamartoma of tuberous sclerosis complex.
Journal of the American Academy of Dermatology 2012;66(4):617-21.
2012: Behfar Eivazi; Wolfgang Pfützner; Marion Roessler; Afshin Teymoortash; Jochen A Werner; Rudolf Happle
Port-wine stains are more than skin-deep! Expanding the spectrum of extracutaneous manifestations of nevi flammei of the head and neck.
European journal of dermatology : EJD 2012;22(2):246-51.
2012: Rudolf Happle
Porokeratosis palmaris, plantaris et disseminata vs. porokeratosis of Mibelli.
The British journal of dermatology 2012;166(3):681-2.
2012: Rudolf Happle
Unilateral nevoid telangiectasias with anemic halos: why aren't they twin spots?
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2012;10(2):140; author reply 141.
2012: A W Arnold; Rudolf Happle; P H Itin; Johannes S Kern; M Pigors; Cristina Has
Acromelanosis albo-punctata: a distinct inherited dermatosis with acral spotty dyspigmentation without systemic involvement.
Dermatology (Basel, Switzerland) 2012;224(4):331-9.
2012: Annalisa Patrizi; Michela Tabanelli; Karl-Heinz Grzeschik; Cosimo Misciali; Iria Neri; Rudolf Happle
Multiple basal cell carcinomas in a 38-year-old woman with Goltz syndrome.
Dermatology (Basel, Switzerland) 2012;224(2):97-100.
2012: Rudolf Happle
Rud syndrome does not exist.
European journal of dermatology : EJD 2012;22(1):7.
2011: Rudolf Happle
Superimposed linear psoriasis: a historical case revisited.
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2011;9(12):1027-8; discussion 1029.
2011: Rudolf Happle
Didymosis cesioanemica: an unusual counterpart of phacomatosis cesioflammea.
European journal of dermatology : EJD 2011;21(4):471.
2011: Hiram de Almeida; Franciani Basso; Rudolf Happle; Flávia Reginatto; Rodrigo Duquia
Phacomatosis melanorosea with heterochromia of scalp hair.
European journal of dermatology : EJD 2011;21(4):598-9.
2011: Rudolf Happle
A novel X-linked phenotype caused by hypomorphic EBP mutations.
American journal of medical genetics. Part A 2011;155A(7):1770-1; author reply 1772.
2011: Hiram Larangeira de Almeida; Roberto Coswig Fiss; Rudolf Happle
Macrodactyly with skin hypertrophy: a minimal form of the Proteus syndrome.
Anais brasileiros de dermatologia 2011;86(3):557-9.
2011: Frank Oeffner; Francisco Martinez; Julie Schaffer; Aïcha Salhi; Sandra Monfort; Silvestre Oltra; Ulrike Neidel; Dorothea Bornholdt; Bregje van Bon; Arne König; Rudolf Happle; Karl-Heinz Grzeschik
Intronic mutations affecting splicing of MBTPS2 cause ichthyosis follicularis, alopecia and photophobia (IFAP) syndrome.
Experimental dermatology 2011;20(5):447-9.
2011: Antonio Torrelo; Isabel Colmenero; Leonard Kristal; Lourdes Navarro; Christian Hafner; Angela Hernández-Martín; Luis Requena; Rudolf Happle
Papular epidermal nevus with "skyline" basal cell layer (PENS).
Journal of the American Academy of Dermatology 2011;64(5):888-92.
2011: Olivier Lidove; Bernard Iung; Rudolf Happle; Vincent Descamps
When chest pain reveals a Fabry disease.
Presse médicale (Paris, France : 1983) 2011;40(5):540-4.
2011: Margarita Larralde; Paula Boggio; María Eugenia Abad; Cristina Corbella; Rudolf Happle
Nevus trichilemmocysticus: report of a new case of a recently recognized entity.
Pediatric dermatology 2011;28(3):286-9.
2011: Rudolf Happle; Arne König
Smoker's boils.
Dermatology (Basel, Switzerland) 2011;222(3):282-4.
2010: Rudolf Happle
Superimposed segmental dermatomyositis: an emerging new paradigm.
European journal of dermatology : EJD 2010;20(5):551.
2010: Andreas W Arnold; Rudolf Happle; Peter H Itin
Superimposed linear psoriasis unmasked by therapy with adalimumab.
European journal of dermatology : EJD 2010;20(5):573-4.
2010: Retno Danarti; Karl-Heinz Grzeschik; Sunardi Radiono; Arne König; Rudolf Happle
Left-sided CHILD syndrome caused by a nonsense mutation in exon 7 of the NSDHL gene.
European journal of dermatology : EJD 2010;20(5):634-5.
2010: Rudolf Happle
Giant melanocytic nevus may be explained as a superimposed patchy manifestation of a polygenic trait.
Dermatology (Basel, Switzerland) 2010;221(1):30-3.
2010: Rudolf Happle; Retno Danarti
CHILD syndrome vs. unilateral psoriasis.
International journal of dermatology 2010;49(7):847-8.
2010: Rudolf Happle
The group of epidermal nevus syndromes Part II. Less well defined phenotypes.
Journal of the American Academy of Dermatology 2010;63(1):25-30; quiz 31-2.
2010: Rudolf Happle
The group of epidermal nevus syndromes Part I. Well defined phenotypes.
Journal of the American Academy of Dermatology 2010;63(1):1-22; quiz 23-4.
2010: Simon Jacobelli; Stéphanie Leclerc-Mercier; Rémi Salomon; Olivier Hartmann; Frances Brunelle; Rudolf Happle; Christine Bodemer; Smail Hadj-Rabia
Phacomatosis pigmentokeratotica with nephroblastoma and juvenile hypertension.
Acta dermato-venereologica 2010;90(3):279-82.
2010: Caroline Bussmann; Rudolf Happle; Wolfgang Baar; Thomas Bieber; Gerhard Haidl; Natalija Novak
Superimposed linear lichen planopilaris: another polygenic disorder exemplifying a new genetic concept.
European journal of dermatology : EJD 2010;20(3):269-70.
2010: Rudolf Happle
Type 2 segmental manifestation of "blue rubber bleb nevus syndrome": a reappraisal of 5 case reports.
European journal of dermatology : EJD 2010;20(3):266-8.
2010: Ingo Helbig; Regina Fölster-Holst; Jochen Brasch; Ingrid Hausser; Andreas van Baalen; Hiltrud Muhle; Karsten Alfke; Almuth Caliebe; Ulrich Stephani; Rudolf Happle
Dyschromatosis ptychotropica: an unusual pigmentary disorder in a boy with epileptic encephalopathy and progressive atrophy of the central nervous system-a novel entity?
European journal of pediatrics 2010;169(4):495-500.
2010: Rudolf Happle; Dieter Metze; Angel Vera Casaño
Naevus lentiginosus linearis: A distinct skin disorder.
Acta dermato-venereologica 2010;90(2):210-1.
2010: Rudolf Happle
Speckled lentiginous nevi: no longer one single disorder.
Archives of dermatology 2010;146(2):204.
2010: Rebecca Löhrer; Aysegül Neumann-Acikel; Rüdiger Eming; Karin Hartmann; Heinrich Rasokat; Thomas Krieg; Rudolf Happle; Sabine Eming
A case of linear porokeratosis superimposed on disseminated superficial actinic porokeratosis.
Case reports in dermatology 2010;2(2):130-4.
2010: Rudolf Happle
The rhodoid nevus: a proposed term for a so far unnamed capillary malformation.
Dermatology (Basel, Switzerland) 2010;221(4):317-9.
2010: Laurent Parmentier; Ian Tomlinson; Rudolf Happle; Luca Borradori
Evidence for a new fumarate hydratase gene mutation in a unilateral type 2 segmental leiomyomatosis.
Dermatology (Basel, Switzerland) 2010;221(2):149-53.
2010: Philippe Assouly; Rudolf Happle
A hairy paradox: congenital triangular alopecia with a central hair tuft.
Dermatology (Basel, Switzerland) 2010;221(2):107-9.
2010: Arne König; Jan Skrzypek; Harald Löffler; Frank Oeffner; Karl-Heinz Grzeschik; Rudolf Happle
Donor dominance cures CHILD nevus.
Dermatology (Basel, Switzerland) 2010;220(4):340-5.
2010: Rudolf Happle
Phylloid hypermelanosis: an unusual form of pigmentary mosaicism.
Dermatology (Basel, Switzerland) 2010;220(2):183-5.
2010: Rudolf Happle
Superimposed segmental hemangioma of infancy.
Dermatology (Basel, Switzerland) 2010;220(2):180-2.
2010: Rudolf Happle
Mibelli revisited: a case of type 2 segmental porokeratosis from 1893.
Journal of the American Academy of Dermatology 2010;62(1):136-8.
2009: Rudolf Happle; P Itin; A Torrelo; R Graham-Brown
A non-scientific treatment for patients with psoriasis - advocated in a scientific journal.
Journal of the European Academy of Dermatology and Venereology : JEADV 2009;23(10):1222-3; author reply 1223.
2009: P H Itin; Rudolf Happle
Non-syndromic hereditary basal cell carcinomas: a reduplicated discovery.
Journal of the European Academy of Dermatology and Venereology : JEADV 2009;23(10):1219-20; author reply 1220.
2009: Andrew Ming; Rudolf Happle; Karl-Heinz Grzeschik; Gayle Fischer
Ichthyosis follicularis, alopecia, and photophobia (IFAP) syndrome due to mutation of the gene MBTPS2 in a large Australian kindred.
Pediatric dermatology 2009;26(4):427-31.
2009: Rudolf Happle
Angioma serpiginosum is not caused by PORCN mutations.
European journal of human genetics : EJHG 2009;17(7):881-2; author reply 882.
2009: M Antonia González-Enseñat; Asunción Vicente; Pilar Poo; Vicenç Catalá; M Mar Pérez-Iribarne; Carme Fuster; Esther Geán; Rudolf Happle
Phylloid hypomelanosis and mosaic partial trisomy 13: two cases that provide further evidence of a distinct clinicogenetic entity.
Archives of dermatology 2009;145(5):576-8.
2009: Frank Oeffner; Gayle Fischer; Rudolf Happle; Arne König; Regina C Betz; Dorothea Bornholdt; Ulrike Neidel; María del Carmen Boente; Silke Redler; Javier Romero-Gomez; Aïcha Salhi; Angel Vera-Casaño; Christian Weirich; Karl-Heinz Grzeschik
IFAP syndrome is caused by deficiency in MBTPS2, an intramembrane zinc metalloprotease essential for cholesterol homeostasis and ER stress response.
American journal of human genetics 2009;84(4):459-67.
2009: Rudolf Happle
Speckled lentiginous naevus: which of the two disorders do you mean?
Clinical and experimental dermatology 2009;34(2):133-5.
2009: María del Carmen Boente; Graciela Nadra; Raúl Asial; Rudolf Happle
Pronounced linear calcinosis in a boy with mild dermatomyositis. A further possible example of superimposed segmental manifestation of a polygenic disorder.
Dermatology (Basel, Switzerland) 2009;219(2):155-7.
2008: Rudolf Happle
What is a capillary malformation?
Journal of the American Academy of Dermatology 2008;59(6):1077-9.
2008: Alejandro García-Vargas; Christian Hafner; Adriana G Pérez-Rodríguez; L Ximena Rodríguez-Rojas; Pedro González-Esqueda; Robert Stoehr; Mercedes Hernández-Torres; Rudolf Happle
An epidermal nevus syndrome with cerebral involvement caused by a mosaic FGFR3 mutation.
American journal of medical genetics. Part A 2008;146A(17):2275-9.
2008: Walter Krause; Rudolf Happle
LOH-pitfalls of an ambiguous abbreviation.
The aging male : the official journal of the International Society for the Study of the Aging Male 2008;11(3):150-1.
2008: Knut Brockmann; Rudolf Happle; Frank Oeffner; Arne König
Monozygotic twins discordant for Proteus syndrome.
American journal of medical genetics. Part A 2008;146A(16):2122-5.
2008: María del C Boente; Roxana Obeid; Raúl A Asial; Hilda Bibas-Bonet; Ana M Coronel; Rudolf Happle
Cutis tricolor coexistent with cutis marmorata telangiectatica congenita: "phacomatosis achromico-melano-marmorata".
European journal of dermatology : EJD 2008;18(4):394-6.
2008: Hiram Larangeira de Almeida; Rudolf Happle; Ulrike Blume-Peytavi; Luis Antônio Suita de Castro
Ichthyosis cribriformis: A new entity?
Journal of the American Academy of Dermatology 2008;58(3):505-7.
2008: Chao-Chun Yang; Rudolf Happle; Sheau-Chiou Chao; Julia Yu-Yun Lee; WenChieh Chen
Giant café-au-lait macule in neurofibromatosis 1: a type 2 segmental manifestation of neurofibromatosis 1?
Journal of the American Academy of Dermatology 2008;58(3):493-7.
2008: Marco Castori; Rosanna Rinaldi; Corrado Angelo; Giovanna Zambruno; Paola Grammatico; Rudolf Happle
Phacomatosis cesioflammea with unilateral lipohypoplasia.
American journal of medical genetics. Part A 2008;146A(4):492-5.
2008: Rudolf Happle; Sigrid Tinschert
Segmentally arranged basaloid follicular hamartomas with osseous, dental and cerebral anomalies: a distinct syndrome.
Acta dermato-venereologica 2008;88(4):382-7.
2008: María del Carmen Boente; Raúl A Asial; Rudolf Happle
Phacomatosis pigmentokeratotica: a follow-up report documenting additional cutaneous and extracutaneous anomalies.
Pediatric dermatology 2008;25(1):76-80.
2008: Christian Hafner; Michael Landthaler; Rudolf Happle; Thomas Vogt
Nevus marginatus: a distinct type of epidermal nevus or merely a variant of nevus sebaceus?
Dermatology (Basel, Switzerland) 2008;216(3):236-8.
2008: Sabrina Zietz; Rudolf Happle; Ulrich Hohenleutner; Michael Landthaler
The venous nevus: a distinct vascular malformation suggesting mosaicism.
Dermatology (Basel, Switzerland) 2008;216(1):31-6.
2007: Iliana Tantcheva-Poor; Katja Reinhold; Thomas Krieg; Rudolf Happle
Trichilemmal cyst nevus: a new complex organoid epidermal nevus.
Journal of the American Academy of Dermatology 2007;57(5 Suppl):S72-7.
2007: Rudolf Happle
Superimposed segmental manifestation of polygenic skin disorders.
Journal of the American Academy of Dermatology 2007;57(4):690-9.
2007: Karl-Heinz Grzeschik; Dorothea Bornholdt; Frank Oeffner; Arne König; María del Carmen Boente; Herbert Enders; Barbara Fritz; Michael Hertl; Ute Grasshoff; Katja Höfling; Vinzenz Oji; Mauro Paradisi; Christian Schuchardt; Zsuzsanna Szalai; Gianluca Tadini; Heiko Traupe; Rudolf Happle
Deficiency of PORCN, a regulator of Wnt signaling, is associated with focal dermal hypoplasia.
Nature genetics 2007;39(7):833-5.
2007: Jorge Frank; Rudolf Happle
Cutaneous mosaicism: right before our eyes.
The Journal of clinical investigation 2007;117(5):1216-9.
2007: Rudolf Happle
Linear Cowden nevus: a new distinct epidermal nevus.
European journal of dermatology : EJD 2007;17(2):133-6.
2007: Ken Arita; Witold K Jacyk; Vesarat Wessagowit; Elizabeth Jansen van Rensburg; Tracy Chaplin; Charles A Mein; Masashi Akiyama; Hiroshi Shimizu; Rudolf Happle; John A McGrath
The South African "bathing suit ichthyosis" is a form of lamellar ichthyosis caused by a homozygous missense mutation, p.R315L, in transglutaminase 1.
The Journal of investigative dermatology 2007;127(2):490-3.
2007: Retno Danarti; Arne König; Mario Bittar; Rudolf Happle
Inverse Klippel-Trenaunay syndrome: review of cases showing deficient growth.
Dermatology (Basel, Switzerland) 2007;214(2):130-2.
2007: Rudolf Happle
'Soft medicine' is not always soft: the original sin of German drug legislation.
Dermatology (Basel, Switzerland) 2007;214(2):105-7.
2006: Falk G Bechara; Rudolf Happle; Peter Altmeyer; Stephan Grabbe; Thomas Jansen
Angiokeratoma circumscriptum arranged in a systematized band-like pattern suggesting mosaicism.
The Journal of dermatology 2006;33(7):489-91.
2006: Desanka Raskovic; Sergio Bondanza; Tommaso Gobello; Antonio Luci; Giovanna Zambruno; Rudolf Happle; Liliana Guerra
Autologous in vitro reconstituted epidermis in the treatment of a large nevus depigmentosus.
Journal of the American Academy of Dermatology 2006;54(5 Suppl):S238-40.
2006: Rudolf Happle
X-chromosome inactivation: role in skin disease expression.
Acta paediatrica (Oslo, Norway : 1992). Supplement 2006;95(451):16-23.
2006: Amparo Chabás; Rudolf Happle
Understanding the biology of X-linked diseases.
Acta paediatrica (Oslo, Norway : 1992). Supplement 2006;95(451):9-10.
2006: Mario Bittar; Rudolf Happle; Karl-Heinz Grzeschik; Leonora Leveleki; Michael Hertl; Dorothea Bornholdt; Arne König
CHILD syndrome in 3 generations: the importance of mild or minimal skin lesions.
Archives of dermatology 2006;142(3):348-51.
2006: Antonio Torrelo; Antonio Zambrano; Rudolf Happle
Large aberrant Mongolian spots coexisting with cutis marmorata telangiectatica congenita (phacomatosis pigmentovascularis type V or phacomatosis cesiomarmorata).
Journal of the European Academy of Dermatology and Venereology : JEADV 2006;20(3):308-10.
2006: Patrick H Warnke; Gustav W Schimmelpenning; Rudolf Happle; Ingo N Springer; Axel Hauschild; Jörg Wiltfang; Yahya Acil; Eugene Sherry; Ehrhardt Proksch; J Luettges; Paul A J Russo
Intraoral lesions associated with sebaceous nevus syndrome.
Journal of cutaneous pathology 2006;33(2):175-80.
2006: WenChieh Chen; Ta-Ju Liu; Yi-Chien Yang; Rudolf Happle
Angioma serpiginosum arranged in a systematized segmental pattern suggesting mosaicism.
Dermatology (Basel, Switzerland) 2006;213(3):236-8.
2006: Rudolf Happle
Linear psoriasis and ILVEN: is lumping or splitting appropriate?
Dermatology (Basel, Switzerland) 2006;212(2):101-2.
2006: Helena Vidaurri-de la Cruz; Rudolf Happle
Two distinct types of speckled lentiginous nevi characterized by macular versus papular speckles.
Dermatology (Basel, Switzerland) 2006;212(1):53-8.
2005: Pia Freyschmidt-Paul; M Zoller; Kevin J McElwee; J Sundberg; Rudolf Happle; Rolf Hoffmann
The functional relevance of the type 1 cytokines IFN-gamma and IL-2 in alopecia areata of C3H/HeJ mice.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2005;10(3):282-3.
2005: Antonio Torrelo; Eulalia Baselga; Eduardo Nagore; Antonio Zambrano; Rudolf Happle
Delineation of the various shapes and patterns of nevi.
European journal of dermatology : EJD 2005;15(6):439-50.
2005: Mario Bittar; Rudolf Happle
Revertant mosaicism and retrotransposons: another explanation of "natural gene therapy".
American journal of medical genetics. Part A 2005;137(2):222.
2005: Rudolf Happle
Nevus roseus: a distinct vascular birthmark.
European journal of dermatology : EJD 2005;15(4):231-4.
2005: Claudia Jonak; Dieter Metze; Heiko Traupe; Rudolf Happle; Arne König; Franz Trautinger
The expression of the 27-kd heat shock protein in keratinization disorders: an immunohistological study.
Human pathology 2005;36(6):686-93.
2005: Antonio Torrelo; María del Carmen Boente; Olga Nieto; Raúl A Asial; Isabel Colmenero; Beatriz C Winik; Antonio Zambrano; Rudolf Happle
Nevus psiloliparus and aplasia cutis: a further possible example of didymosis.
Pediatric dermatology 2005;22(3):206-9.
2005: Rudolf Happle
Phacomatosis pigmentovascularis revisited and reclassified.
Archives of dermatology 2005;141(3):385-8.
2005: Patrick H Warnke; Paul A J Russo; Gustav W Schimmelpenning; Rudolf Happle; Franz Härle; Axel Hauschild; Eugene Sherry; Jutta Luttges; Hendrik Terheyden; Anton Dunsche; Ingo N Springer
Linear intraoral lesions in the sebaceous nevus syndrome.
Journal of the American Academy of Dermatology 2005;52(2 Suppl 1):62-4.
2005: Rudolf Happle
Linear lichen planus of the face and neck versus amalgam-induced "isotopic" cutaneous lichen planus.
Journal of the American Academy of Dermatology 2005;52(2):375.
2005: Dorothea Bornholdt; Arne König; Rudolf Happle; Leonora Leveleki; Mario Bittar; Retno Danarti; A Vahlquist; W Tilgen; U Reinhold; A Poiares Baptista; E Grosshans; Pierre VABRES; Shiro Niiyama; K Sasaoka; T Tanaka; A L Meiss; P A Treadwell; D Lambert; F Camacho; Karl-Heinz Grzeschik
Mutational spectrum of NSDHL in CHILD syndrome.
Journal of medical genetics 2005;42(2):e17.
2005: Chong A Kim; A Konig; Débora R Bertola; Lilian Maria José Albano; G J F Gattás; Dorothea Bornholdt; Leonora Leveleki; Rudolf Happle; Karl-Heinz Grzeschik
CHILD syndrome caused by a deletion of exons 6-8 of the NSDHL gene.
Dermatology (Basel, Switzerland) 2005;211(2):155-8.
2005: Margarita Larralde; Rudolf Happle
Cutis tricolor parvimaculata: a distinct neurocutaneous syndrome?
Dermatology (Basel, Switzerland) 2005;211(2):149-51.
2005: Mario Bittar; Retno Danarti; Arne König; Andreas Gal; Rudolf Happle
Late-onset familial onychodystrophy heralding incontinentia pigmenti.
Acta dermato-venereologica 2005;85(3):274-5.
2005: Mario Bittar; Rudolf Happle
'Atypical' cases of hailey-hailey disease may represent typical examples of a type 2 segmental manifestation.
Dermatology (Basel, Switzerland) 2005;210(3):182-3.
2005: Rudolf Happle
Trichotemnomania: obsessive-compulsive habit of cutting or shaving the hair.
Journal of the American Academy of Dermatology 2005;52(1):157-9.
2004: Retno Danarti; Arne König; Aïcha Salhi; Mario Bittar; Rudolf Happle
Becker's nevus syndrome revisited.
Journal of the American Academy of Dermatology 2004;51(6):965-9.
2004: Vazken M Der Kaloustian; Rudolf Happle
Genetic diseases of the skin: progress and perspectives.
American journal of medical genetics. Part C, Seminars in medical genetics 2004;131C(1):1-3.
2004: Benedikt J Folz; Burkard M Lippert; Ana Cerra Wollstein; Julia Tennie; Rudolf Happle; Jochen Werner
Mucocutaneous telangiectases of the head and neck in individuals with hereditary hemorrhagic telangiectasia -- analysis of distribution and symptoms.
European journal of dermatology : EJD 2004;14(6):407-11.
2004: Pamela Poblete Gutiérrez; Tonio Wiederholt; Arne König; Frank K Jugert; Yvonne Marquardt; Albert Rübben; Hans F Merk; Rudolf Happle; Jorge Frank
Allelic loss underlies type 2 segmental Hailey-Hailey disease, providing molecular confirmation of a novel genetic concept.
The Journal of clinical investigation 2004;114(10):1467-74.
2004: Rudolf Happle
[Patterns on the skin. New aspects of their embryologic and genetic causes].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2004;55(10):960-1, 964-8.
2004: Rudolf Happle; Stefan Horster
Nevus psiloliparus: report of two nonsyndromic cases.
European journal of dermatology : EJD 2004;14(5):314-6.
2004: Rudolf Happle
The manifold faces of proteus syndrome.
Archives of dermatology 2004;140(8):1001-2.
2004: Aicha Salhi; Dorothea Bornholdt; Frank Oeffner; Sajid Malik; Ernest Heid; Rudolf Happle; Karl-Heinz Grzeschik
Multiple familial trichoepithelioma caused by mutations in the cylindromatosis tumor suppressor gene.
Cancer research 2004;64(15):5113-7.
2004: Ramon Grimalt; Rudolf Happle
Trichorrhizophagia.
European journal of dermatology : EJD 2004;14(4):266-7.
2004: Peter M Steijlen; Maurice A M van Steensel; Bastiaan Jan Herman Jansen; Willeke A M Blokx; P C M van de Kerkhof; Rudolf Happle; Michel van Geel
Cryptic splicing at a non-consensus splice-donor in a patient with a novel mutation in the plakophilin-1 gene.
The Journal of investigative dermatology 2004;122(5):1321-4.
2004: Rudolf Happle; Joachim Fleiner; Ulrike Loskamp
Kerinokeratosis papulosa with a type 2 segmental manifestation.
Journal of the American Academy of Dermatology 2004;50(5 Suppl):S84-5.
2004: Pia Freyschmidt-Paul; Rudolf Happle; Rolf Hoffman
[Alopecia areata in animal models--new insights into pathogenesis and treatment of a T cell-mediated autoimmune disorder].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2004;2(4):260-73.
2004: Carsten Meyer; Pia Freyschmidt-Paul; Rudolf Happle; Peter Kroll
Unilateral linear hyperpigmentation of the skin with ipsilateral sectorial hyperpigmentation of the retina.
American journal of medical genetics. Part A 2004;126A(1):89-92.
2004: Rudolf Happle
Melorheostosis may originate as a type 2 segmental manifestation of osteopoikilosis.
American journal of medical genetics. Part A 2004;125A(3):221-3.
2004: Mario Bittar; Rudolf Happle
CHILD syndrome avant la lettre.
Journal of the American Academy of Dermatology 2004;50(2 Suppl):S34-7.
2004: Rudolf Happle
What is IFAP syndrome?
American journal of medical genetics. Part A 2004;124A(3):328.
2004: WenChieh Chen; Po-Chyung Fan; Rudolf Happle
Partial unilateral lentiginosis with ipsilateral Lisch nodules and axillary freckling.
Dermatology (Basel, Switzerland) 2004;209(4):321-4.
2004: Claudia Vente; Christine Neumann; Hans Peter Bertsch; Rainer Rupprecht; Rudolf Happle
Speckled lentiginous nevus syndrome: report of a further case.
Dermatology (Basel, Switzerland) 2004;209(3):228-9.
2004: Rudolf Happle
Gustav Schimmelpenning and the syndrome bearing his name.
Dermatology (Basel, Switzerland) 2004;209(2):84-7.
2003: Rudolf Happle
Linear Darier's or Grover's disease?
Journal of the American Academy of Dermatology 2003;49(6):1200-1; author reply 1201.
2003: Retno Danarti; Rudolf Happle
Paradominant inheritance of twin spotting: phacomatosis pigmentovascularis as a further possible example.
European journal of dermatology : EJD 2003;13(6):612.
2003: Antonio Torrelo; Inmaculada de Prada; Antonio Zambrano; Rudolf Happle
Extensive speckled lentiginous nevus associated with giant congenital melanocytic nevus: an unusual example of twin spotting?
European journal of dermatology : EJD 2003;13(6):534-6.
2003: Yuin-Chew Chan; Rudolf Happle; Yoke-Chin Giam
Whorled scarring alopecia: a rare phenomenon in incontinentia pigmenti?
Journal of the American Academy of Dermatology 2003;49(5):929-31.
2003: Retno Danarti; Arne König; Rudolf Happle
Large congenital melanocytic nevi may reflect paradominant inheritance implying allelic loss.
European journal of dermatology : EJD 2003;13(5):430-2.
2003: Yuin-Chew Chan; Yong-Kwang Tay; Lawrence Kang-Seng Tan; Rudolf Happle; Yoke-Chin Giam
Harlequin ichthyosis in association with hypothyroidism and juvenile rheumatoid arthritis.
Pediatric dermatology 2003;20(5):421-6.
2003: Rudolf Happle
A fresh look at incontinentia pigmenti.
Archives of dermatology 2003;139(9):1206-8.
2003: Retno Danarti; Mario Bittar; Rudolf Happle; Arne König
Linear atrophoderma of Moulin: postulation of mosaicism for a predisposing gene.
Journal of the American Academy of Dermatology 2003;49(3):492-8.
2003: Pia Freyschmidt-Paul; Rudolf Happle; Rolf Hoffmann
[Alopecia areata. Clinical aspects, pathogenesis and rational therapy of a T-cell-induced autoimmune disease].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2003;54(8):713-22.
2003: Rudolf Happle
Congenital triangular alopecia may be categorized as a paradominant trait.
European journal of dermatology : EJD 2003;13(4):346-7.
2003: Mete Baba; Deniz Seçkin; Cenk Akçali; Rudolf Happle
Familial cutis tricolor: a possible example of paradominant inheritance.
European journal of dermatology : EJD 2003;13(4):343-5.
2003: Pia Freyschmidt-Paul; Kevin J McElwee; Vladimir A Botchkarev; Sabine Kissling; Elke Wenzel; John P Sundberg; Rudolf Happle; Rolf Hoffmann
Fas-deficient C3.MRL-Tnfrsf6(lpr) mice and Fas ligand-deficient C3H/HeJ-Tnfsf6(gld) mice are relatively resistant to the induction of alopecia areata by grafting of alopecia areata-affected skin from C3H/HeJ mice.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2003;8(1):104-8.
2003: Rodney Sinclair; Damian Jolley; Rica Mallari; Jill Magee; Antonella Tosti; Bianca Maria Piracinni; C Vincenzi; Rudolf Happle; Juan Ferrando; Ramon Grimalt; Leroy Thérèse; Dominique Van Neste; Abraham Zlotogorski; Angela M Christiano; David A Whiting
Morphological approach to hair disorders.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2003;8(1):56-64.
2003: Pia Freyschmidt-Paul; Rudolf Happle; Kevin J McElwee; Rolf Hoffmann
Alopecia areata: treatment of today and tomorrow.
The journal of investigative dermatology. Symposium proceedings / the Society for Investigative Dermatology, Inc. [and] European Society for Dermatological Research 2003;8(1):12-7.
2003: WenChieh Chen; Rudolf Happle
Phacomatosis pigmentovasculosebacea: an unusual case of phacomatosis multiplex.
European journal of dermatology : EJD 2003;13(3):231-3.
2003: Rudolf Happle
Sturge-Weber-Klippel-Trenaunay syndrome: what's in a name?
European journal of dermatology : EJD 2003;13(3):223.
2003: Rudolf Happle; Karl Holubar
An eye for an eye....(Exodus xxi:23,24).
The Journal of investigative dermatology 2003;120(5):893-4.
2003: Barbara Gansz; Rudolf Happle; Dieter Metze; Markus Böhm
[Linear symptomless skin atrophy in a 14-year old girl].
Journal der Deutschen Dermatologischen Gesellschaft = Journal of the German Society of Dermatology : JDDG 2003;1(4):319-21.
2003: Antonio Torrelo; Antonio Zambrano; Rudolf Happle
Cutis marmorata telangiectatica congenita and extensive mongolian spots: type 5 phacomatosis pigmentovascularis.
The British journal of dermatology 2003;148(2):342-5.
2003: Harald Loffler; Rudolf Happle
Influence of climatic conditions on the irritant patch test with sodium lauryl sulphate.
Acta dermato-venereologica 2003;83(5):338-41.
2003: Harald Löffler; Anja Steffes; Rudolf Happle; Isaak Effendy
Allergy and irritation: an adverse association in patients with atopic eczema.
Acta dermato-venereologica 2003;83(5):328-31.
2003: Hiram Larangeira de Almeida; Rudolf Happle
Two cases of cephalic Becker nevus with asymmetrical growth of beard or scalp hair.
Dermatology (Basel, Switzerland) 2003;207(3):337-8.
2003: Markus Zutt; F Strutz; Rudolf Happle; E M Habenicht; Steffen Emmert; Holger A Haenssle; Lutz Kretschmer; Ch Neumann
Schimmelpenning-Feuerstein-Mims syndrome with hypophosphatemic rickets.
Dermatology (Basel, Switzerland) 2003;207(1):72-6.
2003: Harald Löffler; Rudolf Happle
Profile of irritant patch testing with detergents: sodium lauryl sulfate, sodium laureth sulfate and alkyl polyglucoside.
Contact dermatitis 2003;48(1):26-32.
2003: Sigrid Tinschert; Anette Stein; Burkhard Göldner; Manfred Dietel; Rudolf Happle
Melorheostosis with ipsilateral nevus sebaceus (didymosis melorheosebacea).
European journal of dermatology : EJD 2003;13(1):21-4.
2002: Rudolf Happle
Dohi Memorial Lecture. New aspects of cutaneous mosaicism.
The Journal of dermatology 2002;29(11):681-92.
2002: Olivia López-Barrantes; Antonio Torrelo; Imelda G Mediero; Antonio Zambrano; Rudolf Happle
Nevoid hypertrichosis and hypomelanosis.
European journal of dermatology : EJD 2002;12(6):583-5.
2002: Pia Freyschmidt-Paul; Kevin J McElwee; Rudolf Happle; Sabine Kissling; Elke Wenzel; John P Sundberg; Margot Zöller; Rolf Hoffmann
Interleukin-10-deficient mice are less susceptible to the induction of alopecia areata.
The Journal of investigative dermatology 2002;119(4):980-2.
2002: Antonella Tosti; Bianca Maria Piraccini; Wilma F Bergfeld; Francisco Camacho; R P R Dawber; Rudolf Happle; Elise A Olsen; Vera H Price; Alfredo Rebora; Jerry Shapiro; Rodney Sinclair; Dominique Vanneste; David A Whiting
Occupational alopecia or alopecia areata?
Journal of the American Academy of Dermatology 2002;47(4):636-7.
2002: Denise Horn; Rudolf Happle; Heidemarie Neitzel; Jürgen Kunze
Pigmentary mosaicism of the hyperpigmented type in two half-brothers.
American journal of medical genetics 2002;112(1):65-9.
2002: Harald Löffler; Heinrich Dickel; Thomas Bruckner; Isaak Effendy; Rudolf Happle
Skin changes in geriatric nurses prior to training heralding a particular risk of hand dermatitis.
European journal of dermatology : EJD 2002;12(5):452-4.
2002: Rolf Hoffmann; Shiro Niiyama; Andrea Huth; Sabine Kissling; Rudolf Happle
17alpha-estradiol induces aromatase activity in intact human anagen hair follicles ex vivo.
Experimental dermatology 2002;11(4):376-80.
2002: Harald Löffler; J U N Aramaki; K Friebe; Rudolf Happle; Isaak Effendy
Changes in skin physiology during bath PUVA therapy.
The British journal of dermatology 2002;147(1):105-9.
2002: Desmond J Tobin; Sarah H Gardner; Nigel J Lindsey; Rolf Hoffmann; Rudolf Happle; Pia Freyschmidt-Paul
Diphencyprone immunotherapy alters anti-hair follicle antibody status in patients with alopecia areata.
European journal of dermatology : EJD 2002;12(4):327-34.
2002: Mete Baba; Cenk Akcali; Deniz Seçkin; Rudolf Happle
Segmental lentiginosis with ipsilateral nevus depigmentosus: another example of twin spotting?
European journal of dermatology : EJD 2002;12(4):319-21.
2002: J U N Aramaki; Seiji Kawana; Isaak Effendy; Rudolf Happle; Harald Löffler
Differences of skin irritation between Japanese and European women.
The British journal of dermatology 2002;146(6):1052-6.
2002: Michel van Geel; Maurice A M van Steensel; Wolfgang Küster; Hans Christian Hennies; Rudolf Happle; Peter M Steijlen; A König
HID and KID syndromes are associated with the same connexin 26 mutation.
The British journal of dermatology 2002;146(6):938-42.
2002: Rudolf Happle
Segmental lesions are not always agminated.
Archives of dermatology 2002;138(6):838.
2002: Arne König; Rudolf Happle; Regina Fink-Puches; Hans Peter Soyer; Dorothea Bornholdt; Hartmut Engel; Karl-Heinz Grzeschik
A novel missense mutation of NSDHL in an unusual case of CHILD syndrome showing bilateral, almost symmetric involvement.
Journal of the American Academy of Dermatology 2002;46(4):594-6.
2002: Rudolf Happle
Speckled lentiginous nevus syndrome: delineation of a new distinct neurocutaneous phenotype.
European journal of dermatology : EJD 2002;12(2):133-5.
2002: Rudolf Happle; Maureen Rogers
Epidermal nevi.
Advances in dermatology 2002;18():175-201.
2002: Peter H Itin; Rudolf Happle
Darier disease with paired segmental manifestation of either excessive or absent involvement: a further step in the concept of twin spotting.
Dermatology (Basel, Switzerland) 2002;205(4):344-7.
2002: Shiro Niiyama; Kensei Katsuoka; Rudolf Happle; Rolf Hoffmann
Multiple eruptive dermatofibromas: a review of the literature.
Acta dermato-venereologica 2002;82(4):241-4.
2002: Rudolf Happle
Transposable elements and the lines of Blaschko: a new perspective.
Dermatology (Basel, Switzerland) 2002;204(1):4-7.
2002: Rudolf Happle
Diphencyprone for the treatment of alopecia areata: more data and new aspects.
Archives of dermatology 2002;138(1):112-3.
2001: Rudolf Happle
History of German medicine and its influence on the spirit of Japanese dermatology.
The Journal of dermatology 2001;28(11):709-14.
2001: J U N Aramaki; C Löffler; Seiji Kawana; Isaak Effendy; Rudolf Happle; Harald Löffler
Irritant patch testing with sodium lauryl sulphate: interrelation between concentration and exposure time.
The British journal of dermatology 2001;145(5):704-8.
2001: J U N Aramaki; Isaak Effendy; Rudolf Happle; Seiji Kawana; C Löffler; Harald Löffler
Which bioengineering assay is appropriate for irritant patch testing with sodium lauryl sulfate?
Contact dermatitis 2001;45(5):286-90.
2001: Shiro Niiyama; Rudolf Happle; Rolf Hoffmann
Guess what! Multiple disseminated dermatofibromas in a woman with systemic lupus erythematosus.
European journal of dermatology : EJD 2001;11(5):475-6.
2001: Harald Löffler; C Pirker; J U N Aramaki; Peter J Frosch; Rudolf Happle; Isaak Effendy
Evaluation of skin susceptibility to irritancy by routine patch testing with sodium lauryl sulfate.
European journal of dermatology : EJD 2001;11(5):416-9.
2001: Pia Freyschmidt-Paul; A Ziegler; Kevin J McElwee; Rudolf Happle; Sabine Kissling; John P Sundberg; Rolf Hoffmann
Treatment of alopecia areata in C3H/HeJ mice with the topical immunosuppressant FK506 (Tacrolimus).
European journal of dermatology : EJD 2001;11(5):405-9.
2001: Andrea Krisp; Arne König; Rolf Hoffmann; Rudolf Happle
Guess what! X-linked dominant chondrodysplasia punctata (Conradi-Hünermann-Happle Syndrome).
European journal of dermatology : EJD 2001;11(4):389-91.
2001: S Poyanmehr; Pia Freyschmidt-Paul; Rudolf Happle; Rolf Hoffmann
Guess what! Tricho-rhino-phalangeal syndrome type 1.
European journal of dermatology : EJD 2001;11(4):385-7.
2001: S Poyanmehr; Pia Freyschmidt-Paul; Rudolf Happle; Rolf Hoffmann
Guess what! Hypotrichosis simplex.
European journal of dermatology : EJD 2001;11(4):383-4.
2001: S Wilke; Rolf Hoffmann; Rudolf Happle; Pia Freyschmidt-Paul
Guess what! Comèl-Netherton syndrome.
European journal of dermatology : EJD 2001;11(4):381-2.
2001: Shiro Niiyama; Pia Freyschmidt-Paul; Rudolf Happle; Rolf Hoffmann
Guess what! Hypotrichosis congenita of Marie Unna: comment.
European journal of dermatology : EJD 2001;11(4):379-80.
2001: T Küster; Rudolf Happle; Rolf Hoffmann; Pia Freyschmidt-Paul
Guess what! Atrichia with papular lesions.
European journal of dermatology : EJD 2001;11(4):375-7.
2001: Andrea Krisp; R Hoffman; Rudolf Happle; Arne König; Pia Freyschmidt-Paul
Hermansky-Pudlak syndrome.
European journal of dermatology : EJD 2001;11(4):372-3.
2001: Pia Freyschmidt-Paul; Rolf Hoffmann; Rudolf Happle
Trichoteiromania.
European journal of dermatology : EJD 2001;11(4):369-71.
2001: Shiro Niiyama; S Koelker; I Degen; G F Hoffmann; Rudolf Happle; Rolf Hoffmann
Acrodermatitis acidemica secondary to malnutrition in glutaric aciduria type I.
European journal of dermatology : EJD 2001;11(3):244-6.
2001: Shiro Niiyama; Rudolf Happle; Rolf Hoffmann
Influence of estrogens on the androgen metabolism in different subunits of human hair follicles.
European journal of dermatology : EJD 2001;11(3):195-8.
2001: Rudolf Happle; A Assim
The lines of Blaschko on the head and neck.
Journal of the American Academy of Dermatology 2001;44(4):612-5.
2001: Shiro Niiyama; Rudolf Happle; Rolf Hoffmann
The feasibility of quantitative analysis of androgen metabolism by use of single dermal papillae from human hair follicles.
Experimental dermatology 2001;10(2):124-7.
2001: Rudolf Happle
Genetic hair loss.
Clinics in dermatology 2001;19(2):121-8.
2001: Harald Löffler; Rolf Hoffmann; Rudolf Happle; Isaak Effendy
Murine auricular transepidermal water loss -- a novel approach for evaluating irritant skin reaction in mice.
Clinical and experimental dermatology 2001;26(2):196-200.
2001: Pia Freyschmidt-Paul; Rolf Hoffmann; E Levine; John P Sundberg; Rudolf Happle; Kevin J McElwee
Current and potential agents for the treatment of alopecia areata.
Current pharmaceutical design 2001;7(3):213-30.
2001: Retno Danarti; Rudolf Happle; Arne König
Paradominant inheritance may explain familial occurrence of Cutis marmorata telangiectatica congenita.
Dermatology (Basel, Switzerland) 2001;203(3):208-11.
2001: Rudolf Happle; A König
Didymosis aplasticosebacea: coexistence of aplasia cutis congenita and nevus sebaceus may be explained as a twin spot phenomenon.
Dermatology (Basel, Switzerland) 2001;202(3):246-8.
2000: Shiro Niiyama; K Kojima; T Hamada; Rudolf Happle; Rolf Hoffmann
The novel drug CS-891 inhibits 5alpha-reductase activity in freshly isolated dermal papilla of human hair follicles.
European journal of dermatology : EJD 2000;10(8):593-5.
2000: Arne König; Rudolf Happle
Two cases of type 2 segmental manifestation in a family with cutaneous leiomyomatosis.
European journal of dermatology : EJD 2000;10(8):590-2.
2000: Rudolf Happle
Nonsyndromic type of hereditary multiple basal cell carcinoma.
American journal of medical genetics 2000;95(2):161-3.
2000: Rudolf Happle
Phylloid hypomelanosis is closely related to mosaic trisomy 13.
European journal of dermatology : EJD 2000;10(7):511-2.
2000: Pia Freyschmidt-Paul; S Seiter; Margot Zöller; A König; A Ziegler; John P Sundberg; Rudolf Happle; Rolf Hoffmann
Treatment with an anti-CD44v10-specific antibody inhibits the onset of alopecia areata in C3H/HeJ mice.
The Journal of investigative dermatology 2000;115(4):653-7.
2000: S Gardner; Pia Freyschmidt-Paul; R Hoffmann; J P Sundberg; Rudolf Happle; Nigel J Lindsey; Desmond J Tobin
Normalisation of hair follicle morphology in C3H/HeJ alopecia areata mice after treatment with squaric acid dibutylester.
European journal of dermatology : EJD 2000;10(6):443-50.
2000: Rolf Hoffmann; Rudolf Happle
Current understanding of androgenetic alopecia. Part II: clinical aspects and treatment.
European journal of dermatology : EJD 2000;10(5):410-7.
2000: Rolf Hoffmann; Rudolf Happle
Current understanding of androgenetic alopecia. Part I: etiopathogenesis.
European journal of dermatology : EJD 2000;10(4):319-27.
2000: Arne König; S Hörster; F Vakilzadeh; Rudolf Happle
Type 2 segmental manifestation of Hailey-Hailey disease: poor therapeutic response to dermabrasion is due to severe involvement of adnexal structures.
European journal of dermatology : EJD 2000;10(4):265-8.
2000: Peter M Steijlen; HE Viëtor; Maurice A M van Steensel; Rudolf Happle
Sweat testing in hypomelanosis of Ito: divergent results reflecting genetic heterogeneity.
European journal of dermatology : EJD 2000;10(3):217-9.
2000: Harald Löffler; Isaak Effendy; Rudolf Happle
[Irritant contact dermatitis].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2000;51(3):203-15.
2000: T Küster; U Wentscher; Rudolf Happle
Guess what! Urticaria factitia (itching urticarial dermographism) released by suction disks of an electrocardiograph.
European journal of dermatology : EJD 2000;10(2):151-2.
2000: U Wentscher; Rudolf Happle
Linear verrucous hemangioma.
Journal of the American Academy of Dermatology 2000;42(3):516-8.
2000: Arne König; Rudolf Happle; Dorothea Bornholdt; Hartmut Engel; Karl-Heinz Grzeschik
Mutations in the NSDHL gene, encoding a 3beta-hydroxysteroid dehydrogenase, cause CHILD syndrome.
American journal of medical genetics 2000;90(4):339-46.
2000: Tommaso Gobello; Cinzia Mazzanti; Giovanna Zambruno; Luca M Chinni; Rudolf Happle
New type of epidermal nevus syndrome.
Dermatology (Basel, Switzerland) 2000;201(1):51-3.
2000: Arne König; Rudolf Happle; E Tchitcherina; J R Schaefer; Piotr Sokolowski; Wolfgang Köhler; Rolf Hoffmann
An X-linked gene involved in androgenetic alopecia: a lesson to be learned from adrenoleukodystrophy.
Dermatology (Basel, Switzerland) 2000;200(3):213-8.
2000: Maurice A M van Steensel; Rudolf Happle; Peter M Steijlen
Molecular genetics of the hair follicle: the state of the art.
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) 2000;223(1):1-7.
2000: Rudolf Happle
Quo vadis dermatology? From a German perspective, cloudy.
Archives of dermatology 2000;136(1):50-1.
1999: P Freyschmidt-Paul; R Hoffmann; A König; Rudolf Happle
Linear porokeratosis superimposed on disseminated superficial actinic porokeratosis: report of two cases exemplifying the concept of type 2 segmental manifestation of autosomal dominant skin disorders.
Journal of the American Academy of Dermatology 1999;41(4):644-7.
1999: Rudolf Happle; P H Itin; A M Brun
Type 2 segmental Darier disease.
European journal of dermatology : EJD 1999;9(6):449-51.
1999: Arne König; Rudolf Happle
Linear lesions reflecting lyonization in women heterozygous for IFAP syndrome (ichthyosis follicularis with atrichia and photophobia).
American journal of medical genetics 1999;85(4):365-8.
1999: Rudolf Happle
Loss of heterozygosity in human skin.
Journal of the American Academy of Dermatology 1999;41(2 Pt 1):143-64.
1999: Pia Freyschmidt-Paul; John P Sundberg; Rudolf Happle; Kevin J McElwee; S Metz; Dawnalyn Boggess; Rolf Hoffmann
Successful treatment of alopecia areata-like hair loss with the contact sensitizer squaric acid dibutylester (SADBE) in C3H/HeJ mice.
The Journal of investigative dermatology 1999;113(1):61-8.
1999: Rudolf Happle
Elattoproteus syndrome: delineation of an inverse form of Proteus syndrome.
American journal of medical genetics 1999;84(1):25-8.
1999: Rolf Hoffmann; Rudolf Happle
[Alopecia areata. Part 2: Therapy].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1999;50(4):W310-5.
1999: Rolf Hoffmann; Rudolf Happle
[Alopecia areata. 1: Clinical aspects, etiology, pathogenesis].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1999;50(3):W222-31.
1999: Pia Freyschmidt-Paul; H Hamm; Rudolf Happle; Rolf Hoffmann
Pronounced perifollicular lymphocytic infiltrates in alopecia areata are associated with poor treatment response to diphencyprone.
European journal of dermatology : EJD 1999;9(2):111-4.
1999: Gudula Kirtschig; Hannelore Mittag; M Wolf; A Gorski; Rudolf Happle
Three different autoimmune bullous diseases in one family: is there a common genetic base?
The British journal of dermatology 1999;140(2):322-7.
1999: Rolf Hoffmann; Rudolf Happle
Finasteride is the main inhibitor of 5alpha-reductase activity in microdissected dermal papillae of human hair follicles.
Archives of dermatological research 1999;291(2-3):100-3.
1999: Rudolf Happle; Arne König
Type 2 segmental manifestation of multiple glomus tumors: A review and reclassification of 5 case reports.
Dermatology (Basel, Switzerland) 1999;198(3):270-2.
1999: Arne König; C Lehmann; R Rompel; Rudolf Happle
Cigarette smoking as a triggering factor of hidradenitis suppurativa.
Dermatology (Basel, Switzerland) 1999;198(3):261-4.
1999: Rudolf Happle; Rolf Hoffmann
Absence of male-pattern baldness in men with X-linked recessive ichthyosis? A hypothesis to be challenged.
Dermatology (Basel, Switzerland) 1999;198(3):231-2.
1999: H Loffler; Isaak Effendy; Rudolf Happle
Skin susceptibility to dithranol: contact allergy or irritation?
European journal of dermatology : EJD 1999;9(1):32-4.
1999: A Konig; G Wennemuth; H P Soyer; Rolf Hoffmann; Rudolf Happle; W Krause
Vulvar amyloidosis mimicking giant condylomata acuminata in a patient with multiple myeloma.
European journal of dermatology : EJD 1999;9(1):29-31.
1998: Rudolf Happle
The essence of alternative medicine. A dermatologist's view from Germany.
Archives of dermatology 1998;134(11):1455-60.
1998: Rolf Hoffmann; Rudolf Happle; R Paus
Elements of the interleukin-1 signaling system show hair cycle-dependent gene expression in murine skin.
European journal of dermatology : EJD 1998;8(7):475-7.
1998: Pia Freyschmidt-Paul; C H Rieger; Rudolf Happle; Rolf Hoffmann
[Neonatal lupus erythematosus and maternal HELLP syndrome: is there a pathogenetic link?].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1998;49(8):662-5.
1998: Gudula Kirtschig; Reiner Mengel; Hannelore Mittag; Lavin Flores-de-Jacoby; Rudolf Happle
Desquamative gingivitis and balanitis--linear IgA disease or cicatricial pemphigoid?
Clinical and experimental dermatology 1998;23(4):173-7.
1998: Rudolf Happle; Wolfgang Küster
Nevus psiloliparus: a distinct fatty tissue nevus.
Dermatology (Basel, Switzerland) 1998;197(1):6-10.
1997: Rudolf Happle
A rule concerning the segmental manifestation of autosomal dominant skin disorders. Review of clinical examples providing evidence for dichotomous types of severity.
Archives of dermatology 1997;133(12):1505-9.
1997: Wolfgang Eicheler; Andrea Huth; Rudolf Happle; Rolf Hoffmann
Phorbol-myristate-acetate, but not interleukin-1 beta or insulin-like growth factor-I, regulates protein kinase C isoenzymes in human dermal papilla cells.
Acta dermato-venereologica 1997;77(5):361-4.
1997: Rudolf Happle; Gotthold Barbi; D Eckert; Ingo Kennerknecht
"Cutis tricolor": congenital hyper- and hypopigmented macules associated with a sporadic multisystem birth defect: an unusual example of twin spotting?
Journal of medical genetics 1997;34(8):676-8.
1997: A König; Rudolf Happle; Rolf Hoffmann
IFN-gamma-induced HLA-DR but not ICAM-1 expression on cultured dermal papilla cells is downregulated by TNF-alpha.
Archives of dermatological research 1997;289(8):466-70.
1997: Andreas Leonhardt; M Krauss; U Gieler; Horst Schweer; Rudolf Happle; Hannsjörg W Seyberth
In vivo formation of prostaglandin E1 and prostaglandin E2 in atopic dermatitis.
The British journal of dermatology 1997;136(3):337-40.
1997: Rudolf Happle; R J Koopman
Becker nevus syndrome.
American journal of medical genetics 1997;68(3):357-61.
1997: Rudolf Happle
Cancer proneness of linear porokeratosis may be explained by allelic loss.
Dermatology (Basel, Switzerland) 1997;195(1):20-5.
1997: Rudolf Happle; P M Steijlen; U Theile; D Karitzky; S Tinschert; H Albrecht-Nebe; Wolfgang Küster
Patchy dermal hypoplasia as a characteristic feature of Proteus syndrome.
Archives of dermatology 1997;133(1):77-80.
1997: Rolf Hoffmann; Wolfgang Eicheler; Elke Wenzel; Rudolf Happle
Interleukin-1beta-induced inhibition of hair growth in vitro is mediated by cyclic AMP.
The Journal of investigative dermatology 1997;108(1):40-2.
1996: Rolf Hoffmann; Rudolf Happle
Topical immunotherapy in alopecia areata. What, how, and why?
Dermatologic clinics 1996;14(4):739-44.
1996: A A Schachtschabel; Wolfgang Küster; Rudolf Happle
[Perifollicular fibroma of the skin and colonic polyps: Hornstein-Knickenberg syndrome].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1996;47(4):304-6.
1996: Rudolf Happle; Isaak Effendy; Mosaad Megahed; S J Orlow; Wolfgang Küster
CHILD syndrome in a boy.
American journal of medical genetics 1996;62(2):192-4.
1996: Rolf Hoffmann; Wolfgang Eicheler; A Huth; E Wenzel; Rudolf Happle
Cytokines and growth factors influence hair growth in vitro. Possible implications for the pathogenesis and treatment of alopecia areata.
Archives of dermatological research 1996;288(3):153-6.
1996: P H van der Steen; H Mittag; Wolfgang Küster; Rudolf Happle
Palmar papillomatous lesions reminiscent of epidermal nevus in a case of focal dermal hypoplasia: a nosological consideration.
Dermatology (Basel, Switzerland) 1996;193(2):147-8.
1996: Rolf Hoffmann; E Wenzel; A Huth; P van der Steen; M Schäufele; A König; Rudolf Happle
Growth factor mRNA levels in alopecia areata before and after treatment with the contact allergen diphenylcyclopropenone.
Acta dermato-venereologica 1996;76(1):17-20.
1995: Wolfgang Eicheler; M Dreher; Rolf Hoffmann; Rudolf Happle; Gerhard Aumüller
Immunohistochemical evidence for differential distribution of 5 alpha-reductase isoenzymes in human skin.
The British journal of dermatology 1995;133(3):371-6.
1995: Rudolf Happle
Epidermal nevus syndromes.
Seminars in dermatology 1995;14(2):111-21.
1995: W Küster; Rudolf Happle
[ADF Symposium "Genetics and dermatology--progress in the recent past--". 29 April-1 may 1994 in Marburg].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1995;46(5):363-6.
1995: Rolf Hoffmann; Rudolf Happle
Analysis of gene expression in isolated single hair follicles: an approach using semiquantitative reverse-transcriptase-polymerase chain reaction.
The Journal of investigative dermatology 1995;104(5 Suppl):20S-21S.
1995: Rudolf Happle; Rolf Hoffmann
Cytokine patterns in alopecia areata before and after topical immunotherapy.
The Journal of investigative dermatology 1995;104(5 Suppl):14S-15S.
1995: Rudolf Happle
What is a nevus? A proposed definition of a common medical term.
Dermatology (Basel, Switzerland) 1995;191(1):1-5.
1995: Rolf Hoffmann; Rudolf Happle
Does interleukin-1 induce hair loss?
Dermatology (Basel, Switzerland) 1995;191(4):273-5.
1995: Rudolf Happle; H Mittag; Wolfgang Küster
The CHILD nevus: a distinct skin disorder.
Dermatology (Basel, Switzerland) 1995;191(3):210-6.
1994: Rudolf Happle
[Grünewald nevus].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1994;45(12):882-3.
1994: Gudula Kirtschig; Rudolf Happle
Stomatopompholyx hemorrhagica.
Journal of the American Academy of Dermatology 1994;31(5 Pt 1):804-5.
1994: Rolf Hoffmann; E Wenzel; A Huth; P van der Steen; M Schäufele; H P Henninger; Rudolf Happle
Cytokine mRNA levels in Alopecia areata before and after treatment with the contact allergen diphenylcyclopropenone.
The Journal of investigative dermatology 1994;103(4):530-3.
1994: P M Steijlen; Hannie Kremer; F Vakilzadeh; Rudolf Happle; A P Lavrijsen; H H Ropers; Edwin C M Mariman
Genetic linkage of the keratin type II gene cluster with ichthyosis bullosa of Siemens and with autosomal dominant ichthyosis exfoliativa.
The Journal of investigative dermatology 1994;103(3):282-5.
1994: P M Steijlen; H A Neumann; D J der Kinderen; D F Smeets; P C van der Kerkhof; Rudolf Happle
Congenital atrichia, palmoplantar hyperkeratosis, mental retardation, and early loss of teeth in four siblings: a new syndrome?
Journal of the American Academy of Dermatology 1994;30(5 Pt 2):893-8.
1994: Rudolf Happle; E Christophers
[Comment on the contribution by S. Pingel: Homeopathy--basic principles and applications in dermatology. A word on homeopathy].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1994;45(2):120-1.
1994: Isaak Effendy; B Ossowski; Rudolf Happle
Fox-Fordyce disease in a male patient--response to oral retinoid treatment.
Clinical and experimental dermatology 1994;19(1):67-9.
1994: Rudolf Happle
[Paraptic eczema. Why a new name?].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1994;45(1):1-3.
1993: Isaak Effendy; B Ossowski; Rudolf Happle
[Pincer nail. Conservative correction by attachment of a plastic brace].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 1993;44(12):800-2.
1993: Rudolf Happle
Mosaicism in human skin. Understanding the patterns and mechanisms.
Archives of dermatology 1993;129(11):1460-70.
1993: Rudolf Happle; O Daniëls; R J Koopman
MIDAS syndrome (microphthalmia, dermal aplasia, and sclerocornea): an X-linked phenotype distinct from Goltz syndrome.
American journal of medical genetics 1993;47(5):710-3.
1993: Wolfgang Küster; Rudolf Happle
Neurocutaneous disorders in children.
Current opinion in pediatrics 1993;5(4):436-40.
1993: W P Arnold; P M Steijlen; Rudolf Happle
Focal dermal hypoplasia (Goltz-Gorlin syndrome).
The British journal of dermatology 1993;129(2):214-5.
1993: H J Van Gerwen; R J Koopman; P M Steijlen; Rudolf Happle
Becker's naevus with localized lipoatrophy and ipsilateral breast hypoplasia.
The British journal of dermatology 1993;129(2):213.
1993: P H van der Steen; Rudolf Happle
Topical immunotherapy of alopecia areata.
Dermatologic clinics 1993;11(3):619-22.
1993: Gudula Kirtschig; Uwe Gieler; Rudolf Happle
Treatment of Hailey-Hailey disease by dermabrasion.
Journal of the American Academy of Dermatology 1993;28(5 Pt 1):784-6.
1993: P M Steijlen; D O Reifenschweiler; F C Ramaekers; G N van Muijen; Rudolf Happle; M Link; D J Ruiter; P C M van de Kerkhof
Topical treatment of ichthyoses and Darier's disease with 13-cis-retinoic acid. A clinical and immunohistochemical study.
Archives of dermatological research 1993;285(4):221-6.
1992: Ben C J Hamel; Rudolf Happle; P M Steylen; L A Kollée; J H Stekhoven; J G Nijhuis; R Rauskolb; I Anton-Lamprecht
False-negative prenatal diagnosis of restrictive dermopathy.
American journal of medical genetics 1992;44(6):824-6.
1992: Isaak Effendy; Uwe Gieler; R Bischoff; Rudolf Happle
Anaphylaxis due to a latex vaginal vibrator.
Contact dermatitis 1992;27(5):318-9.
1992: Isaak Effendy; Rudolf Happle
Linear arrangement of multiple congenital melanocytic nevi.
Journal of the American Academy of Dermatology 1992;27(5 Pt 2):853-4.
1992: Nelleke A Gruis; Jan Nico Bouwes Bavinck; P M Steijlen; J G van der Schroeff; Arie van Haeringen; Rudolf Happle; Edwin C M Mariman; Sylvia van Beersum; J Uitto; Bert-Jan Vermeer
Genetic linkage between the collagen VII (COL7A1) gene and the autosomal dominant form of dystrophic epidermolysis bullosa in two Dutch kindreds.
The Journal of investigative dermatology 1992;99(5):528-30.
1992: P van der Steen; H Traupe; Rudolf Happle; Jan B M Boezeman; R Sträter; H Hamm
The genetic risk for alopecia areata in first degree relatives of severely affected patients. An estimate.
Acta dermato-venereologica 1992;72(5):373-5.
1992: P van der Steen; Jan B M Boezeman; P Duller; Rudolf Happle
Can alopecia areata be triggered by emotional stress? An uncontrolled evaluation of 178 patients with extensive hair loss.
Acta dermato-venereologica 1992;72(4):279-80.
1992: P van der Steen; Rudolf Happle
'Dyschromia in confetti' as a side effect of topical immunotherapy with diphenylcyclopropenone.
Archives of dermatology 1992;128(4):518-20.
1992: H Traupe; P J van Gurp; Rudolf Happle; J Boezeman; P C van de Kerkhof
Psoriasis vulgaris, fetal growth, and genomic imprinting.
American journal of medical genetics 1992;42(5):649-54.
1992: Rudolf Happle; J H Stekhoven; Ben C J Hamel; L A Kollée; J G Nijhuis; I Anton-Lamprecht; P M Steijlen
Restrictive dermopathy in two brothers.
Archives of dermatology 1992;128(2):232-5.
1992: P H van der Steen; Jan B M Boezeman; Rudolf Happle
Topical immunotherapy for alopecia areata: re-evaluation of 139 cases after an additional follow-up period of 19 months.
Dermatology (Basel, Switzerland) 1992;184(3):198-201.
1992: H M van Baar; C M Perret; I M van Vlijmen; P C M van de Kerkhof; Rudolf Happle; Joost Schalkwijk
Abnormal expression of Ki-67 antigen in hair follicle of alopecia areata.
Acta dermato-venereologica 1992;72(3):161-4.
1991: P M Steijlen; R J van Dooren-Greebe; Rudolf Happle; P C M van de Kerkhof
Ichthyosis bullosa of Siemens responds well to low-dosage oral retinoids.
The British journal of dermatology 1991;125(5):469-71.
1991: Rudolf Happle
How many epidermal nevus syndromes exist? A clinicogenetic classification.
Journal of the American Academy of Dermatology 1991;25(3):550-6.
1991: P van der Steen; P C M van de Kerkhof; D der Kinderen; I van Vlijmen; Rudolf Happle
Clinical and immunohistochemical responses of plantar warts to topical immunotherapy with diphenylcyclopropenone.
The Journal of dermatology 1991;18(6):330-3.
1991: Rudolf Happle
Topical immunotherapy in alopecia areata.
The Journal of investigative dermatology 1991;96(5):71S-72S.
1991: P H van der Steen; H M van Baar; C M Perret; Rudolf Happle
Treatment of alopecia areata with diphenylcyclopropenone.
Journal of the American Academy of Dermatology 1991;24(2 Pt 1):253-7.
1991: P H van der Steen; H M van Baar; Rudolf Happle; Jan B M Boezeman; C M Perret
Prognostic factors in the treatment of alopecia areata with diphenylcyclopropenone.
Journal of the American Academy of Dermatology 1991;24(2 Pt 1):227-30.
1991: Rudolf Happle
Allelic somatic mutations may explain vascular twin nevi.
Human genetics 1991;86(3):321-2.
1991: R J Koopman; Rudolf Happle
Autosomal dominant transmission of the NAME syndrome (nevi, atrial myxoma, mucinosis of the skin and endocrine overactivity).
Human genetics 1991;86(3):300-4.
1991: P M Steijlen; Rudolf Happle; G N van Muijen; P C M van de Kerkhof
Topical treatment with 13-cis-retinoic acid improves Darier's disease and induces the expression of a unique keratin pattern.
Dermatologica 1991;182(3):178-83.
1991: H M van Baar; C M Perret; Ivonne M J J van Vlijmen-Willems; J P Cleutjens; E J Mackie; Rudolf Happle; Joost Schalkwijk
Expression of tenascin in perifollicular connective tissue: comparison of normal scalp and alopecia areata.
Archives of dermatological research 1991;283(2):86-90.
1991: Candida A E M van Hooijdonk; P M Steijlen; Mieke Bergers; P D Mier; H Traupe; Rudolf Happle
Epidermal transglutaminase in the ichthyoses.
Acta dermato-venereologica 1991;71(2):173-5.
1991: G Wozel; A Chang; M Zultak; B M Czarnetzki; Rudolf Happle; J Barth; P C M van de Kerkhof
The effect of topical retinoids on the leukotriene-B4-induced migration of polymorphonuclear leukocytes into human skin.
Archives of dermatological research 1991;283(3):158-61.
1990: R J van Dooren-Greebe; P C M van de Kerkhof; P M Steijlen; Rudolf Happle
[Acitretin therapy in keratinization disorders].
Nederlands tijdschrift voor geneeskunde 1990;134(41):1995-2000.
1990: Rudolf Happle
Ptychotropism as a cutaneous feature of the CHILD syndrome.
Journal of the American Academy of Dermatology 1990;23(4 Pt 1):763-6.
1990: Mieke Bergers; H Traupe; S C Dünnwald; P D Mier; R van Dooren-Greebe; P Steijlen; Rudolf Happle
Enzymatic distinction between two subgroups of autosomal recessive lamellar ichthyosis.
The Journal of investigative dermatology 1990;94(4):407-12.
1990: C M Perret; P M Steijlen; Rudolf Happle
Alopecia areata. Pathogenesis and topical immunotherapy.
International journal of dermatology 1990;29(2):83-8.
1990: Rudolf Happle; R Koopman; P D Mier
Hypothesis: vascular twin naevi and somatic recombination in man.
Lancet 1990;335(8686):376-8.
1990: R J Koopman; Rudolf Happle
Cutaneous manifestations of methylmalonic acidemia.
Archives of dermatological research 1990;282(4):272-3.
1990: Rudolf Happle; P M Steijlen; G Kolde
Naevus corniculatus: a new acantholytic disorder.
The British journal of dermatology 1990;122(1):107-12.
1990: G Wozel; A Chang; J Barth; Rudolf Happle; P C M van de Kerkhof
Effect of leukotriene B5 on the accumulation of polymorphonuclear leukocytes in unstimulated and leukotriene B4-stimulated human skin.
Skin pharmacology : the official journal of the Skin Pharmacology Society 1990;3(1):45-8.
1990: P C M van de Kerkhof; P M Steijlen; R J van Dooren-Greebe; Rudolf Happle
Acitretin in the treatment of erythrokeratodermia variabilis.
Dermatologica 1990;181(4):330-3.
1990: P M Steijlen; C M Perret; J H Schuurmans Stekhoven; D J Ruiter; Rudolf Happle
Ichthyosis bullosa of Siemens: further delineation of the phenotype.
Archives of dermatological research 1990;282(1):1-5.
1990: C M Perret; P M Steijlen; H Zaun; Rudolf Happle
Erythema multiforme-like eruptions: a rare side effect of topical immunotherapy with diphenylcyclopropenone.
Dermatologica 1990;180(1):5-7.
1990: A Chang; Joost Schalkwijk; Rudolf Happle; P C M van de Kerkhof
Elastase-inhibiting activity in scaling skin disorders.
Acta dermato-venereologica 1990;70(2):147-51.
1990: Mieke Bergers; P C M van de Kerkhof; Rudolf Happle; P D Mier
Membrane-bound phospholipase C activity in normal and psoriatic epidermis.
Acta dermato-venereologica 1990;70(1):57-9.
1989: R J van Dooren-Greebe; P C M van de Kerkhof; Rudolf Happle
Acitretin monotherapy in Darier's disease.
The British journal of dermatology 1989;121(3):375-9.
1989: C M Perret; Rudolf Happle
Contact allergy to bufexamac.
Contact dermatitis 1989;20(4):307-8.
1989: C M Perret; Rudolf Happle
Contact sensitivity to diazolidinyl urea (Germall II).
Archives of dermatological research 1989;281(1):57-9.
1989: R J van Dooren-Greebe; P C M van de Kerkhof; A Chang; Rudolf Happle
Acitretin monotherapy in acrodermatitis continua Hallopeau.
Acta dermato-venereologica 1989;69(4):344-6.
1989: S de Mare; P C M van de Kerkhof; Rudolf Happle
Dithranol in the treatment of inflammatory linear verrucous epidermal nevus.
Acta dermato-venereologica 1989;69(1):77-80.
1988: C M Perret; Rudolf Happle
Contact allergy to miconazole.
Contact dermatitis 1988;19(1):75.
1988: J J Rijzewijk; F W Bauer; Jan B M Boezeman; Rudolf Happle; P D Mier
Recruitment of quiescent (G0) cells following epidermal injury is initiated by activation of the phosphoinositol cycle.
The Journal of investigative dermatology 1988;90(1):44-7.
1988: P C M van de Kerkhof; A Chang; R van Dooren-Greebe; J M Geiger; Rudolf Happle
Intra-epidermal accumulation of polymorphonuclear leukocytes in persistent palmoplantar pustulosis during treatment with acitretin.
Acta dermato-venereologica 1988;68(6):499-503.
1987: Rudolf Happle; P C M van de Kerkhof; H Traupe
Retinoids in disorders of keratinization: their use in adults.
Dermatologica 1987;175 Suppl 1():107-24.
1987: P C M van de Kerkhof; A M Lammers; P D Mier; Rudolf Happle
Leukotriene B4-induced accumulation of polymorphonuclear leukocytes in psoriatic skin.
Advances in prostaglandin, thromboxane, and leukotriene research 1987;17B():637-9.
1987: A C Dijkstra; A M Vermeesch-Markslag; E W Vromans; Rudolf Happle; P C M van de Kerkhof; Binne Zwanenburg; F Vos; A J Vermorken
Substrate specific sulfatase activity from hair follicles in recessive X-linked ichthyosis.
Acta dermato-venereologica 1987;67(5):369-76.
1986: P D Mier; F W Bauer; Rudolf Happle
Phosphoinositol more than skin deep.
Nature 1986;322(6079):504.