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Akira Hara

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Satoshi Endo; Airi Fujimoto; Ossama El-Kabbani; Sho Kumada; Jun'ichi Mano; Toshiyuki Matsunaga; Satoshi Ohno; Kazuo Tajima; Akira Hara
Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein (AKR1B19) by oxidized glutathione and SH-reagents.
Toshiyuki Matsunaga; Yumi Yamane; Ossama El-Kabbani; Satoshi Endo; Aki Hojo; Akira Hara
Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.
Toshiya Kuno; Sonoko Masuda; Hideki Mori; Akira Hara; Yuichiro Hatano; Akihiro Hirata; Yoshinobu Hirose; Masaru Terasaki; Hiroyuki Tomita; Takuji Tanaka
Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice.

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2013: Satoshi Endo; Airi Fujimoto; Ossama El-Kabbani; Sho Kumada; Jun'ichi Mano; Toshiyuki Matsunaga; Satoshi Ohno; Kazuo Tajima; Akira Hara
Modulation of activity and inhibitor sensitivity of rabbit aldose reductase-like protein (AKR1B19) by oxidized glutathione and SH-reagents.
Chemico-biological interactions 2013;202(1-3):146-52.
2013: Toshiyuki Matsunaga; Yumi Yamane; Ossama El-Kabbani; Satoshi Endo; Aki Hojo; Akira Hara
Pathophysiological roles of aldo-keto reductases (AKR1C1 and AKR1C3) in development of cisplatin resistance in human colon cancers.
Chemico-biological interactions 2013;202(1-3):234-42.
2013: Toshiya Kuno; Sonoko Masuda; Hideki Mori; Akira Hara; Yuichiro Hatano; Akihiro Hirata; Yoshinobu Hirose; Masaru Terasaki; Hiroyuki Tomita; Takuji Tanaka
Organomagnesium suppresses inflammation-associated colon carcinogenesis in male Crj: CD-1 mice.
Carcinogenesis 2013;34(2):361-9.
2013: Satoshi Endo; Airi Fujimoto; Yuki Arai; Ossama El-Kabbani; Munekazu Iinuma; Sho Kumada; Toshiyuki Matsunaga; Hiroshige Mikamo; Yoko Miura; Shigeru Yamano; Akira Hara
Characterization of rabbit morphine 6-dehydrogenase and two NAD(+)-dependent 3α(17β)-hydroxysteroid dehydrogenases.
Archives of biochemistry and biophysics 2013;529(2):131-9.
2013: Nguyen The Cuong; Akira Hara; Hironobu Morita; Chikara Abe; Nguyen Huy Binh; Shinji Ogura
Sivelestat improves outcome of crush injury by inhibiting high-mobility group box 1 in rats.
Shock (Augusta, Ga.) 2013;39(1):89-95.
2013: Akihiro Hirata; Konrad Hochedlinger; Rudolf Jaenisch; Takahiro Kunisada; Hideyuki Okano; Toshikazu Ushijima; Jochen Utikal; Akira Watanabe; Hitomi Aoki; Nabeel Bardeesy; Akira Hara; Takuya Yamamoto; Satoshi Yamashita; Yasuhiro Yamada
Dose-dependent roles for canonical Wnt signalling in de novo crypt formation and cell cycle properties of the colonic epithelium.
Development (Cambridge, England) 2013;140(1):66-75.
2013: Nguyen Huy Binh; Yuichiro Hatano; Akihiro Hirata; Kazuhiro Kobayashi; Toshiya Kuno; Kunio Satoh; Manabu Takamatsu; Hiroyuki Tomita; Akira Hara
Galectin-3 in preneoplastic lesions of glioma.
Journal of neuro-oncology 2013;111(2):123-32.
2012: Yuichiro Hatano; Kenneth E Nollet; Hitoshi Ohto; Setsuko Otsuka; Shunnichi Saito; Katsuya Shimabukuro; Hirofumi Takemura; Mitsuhiro Chousa; Akira Hara
Fatal delayed hemolytic transfusion reaction associated with anti-Di(b) and anti-E.
Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis 2012;47(3):263-8.
2012: Satoshi Endo; Airi Fujimoto; Ossama El-Kabbani; Dawei Hu; Sho Kumada; Jun'ichi Mano; Toshiyuki Matsunaga; Satoshi Ohno; Kazuo Tajima; Naoki Toyooka; Akira Hara
Characterization of rabbit aldose reductase-like protein with 3β-hydroxysteroid dehydrogenase activity.
Archives of biochemistry and biophysics 2012;527(1):23-30.
2012: Wael Goda; Akira Hara; Masaya Nakashima; Kunio Satoh; Masayuki Niwa
PBN fails to suppress in delayed neuronal death of hippocampal CA1 injury following transient forebrain ischemia in gerbils.
Neuroscience letters 2012;517(1):47-51.
2012: Satoshi Endo; Ossama El-Kabbani; Ayano Kanamori; Toshiyuki Matsunaga; Hiroko Nagai; Shozo Ohta; Yoko Otsuji; Krithika Sundaram; Naoki Toyooka; Akira Hara
Selective inhibition of human type-5 17β-hydroxysteroid dehydrogenase (AKR1C3) by baccharin, a component of Brazilian propolis.
Journal of natural products 2012;75(4):716-21.
2012: Masato Hoshi; Hiroyasu Ito; Keishi Matsumoto; Hidetoshi Matsunami; Hirofumi Ohtaki; Yosuke Osawa; Yuko Arioka; Akira Hara; Mitsuru Seishima; Yasuko Yamamoto; Kuniaki Saito
L-tryptophan-kynurenine pathway metabolites regulate type I IFNs of acute viral myocarditis in mice.
Journal of immunology (Baltimore, Md. : 1950) 2012;188(8):3980-7.
2012: Kazuya Hata; Akira Hara; Masaya Kubota; Toshiya Kuno; Hisataka Moriwaki; Masahito Shimizu; Takuji Tanaka; Yoshinobu Hirose
Monosodium glutamate-induced diabetic mice are susceptible to azoxymethane-induced colon tumorigenesis.
Carcinogenesis 2012;33(3):702-7.
2012: Toshiyuki Matsunaga; Yuhki Shinoda; Hiroyuki Tanaka; Gou Watanabe; Ossama El-Kabbani; Satoshi Endo; Mariko Haga; Naoki Inagaki; Yu Kajiwara; Akira Hara
9,10-Phenanthrenequinone promotes secretion of pulmonary aldo-keto reductases with surfactant.
Cell and tissue research 2012;347(2):407-17.
2012: Hitomi Aoki; Takumi Era; Akira Hara; Takahiro Kunisada; Yasuhiro Yamada
Genetic ablation of Rest leads to in vitro-specific derepression of neuronal genes during neurogenesis.
Development (Cambridge, England) 2012;139(4):667-77.
2012: Midori Soda; Keiko Yamamura; Hai-Tao Zhao; Ossama El-Kabbani; Satoshi Endo; Munekazu Iinuma; Toshiyuki Matsunaga; Akira Hara
Inhibition of human aldose reductase-like protein (AKR1B10) by α- and γ-mangostins, major components of pericarps of mangosteen.
Biological & pharmaceutical bulletin 2012;35(11):2075-80.
2012: Toshiyuki Matsunaga; Mika Hosogai; Marina Arakaki; Ossama El-Kabbani; Satoshi Endo; Akira Hara
9,10-phenanthrenequinone induces monocytic differentiation of U937 cells through regulating expression of aldo-keto reductase 1C3.
Biological & pharmaceutical bulletin 2012;35(9):1598-602.
2012: Toshiyuki Matsunaga; Takeshi Miura; Midori Soda; Kazuo Tajima; Mayuko Takemura; Tomoyuki Terada; Keiko Yamamura; Ossama El-Kabbani; Satoshi Endo; Akira Hara
Reduction of cytotoxic p-quinone metabolites of tert-butylhydroquinone by human aldo-keto reductase (AKR) 1B10.
Drug metabolism and pharmacokinetics 2012;27(5):553-8.
2012: Toshiyuki Matsunaga; Midori Soda; Yasuhiro Wada; Ossama El-Kabbani; Satoshi Endo; Akira Hara
Aldo-Keto Reductase 1B10 and Its Role in Proliferation Capacity of Drug-Resistant Cancers.
Frontiers in pharmacology 2012;3():5.
2011: Yuichiro Hatano; Yoshinobu Hirose; Yusuke Kito; Kengo Matsunaga; Hisataka Moriwaki; Shinji Osada; Ichiro Yasuda; Kazuhiro Yoshida; Akira Hara
Combined adenomatoid tumor and well differentiated papillary mesothelioma of the omentum.
Pathology international 2011;61(11):681-5.
2011: Shinichi Yoshimura; Takahiko Asano; Akira Hara; Masayuki Kanematsu; Masanori Kawasaki; Manabu Takamatsu; Kiyofumi Yamada; Toru Iwama
High-intensity signal on time-of-flight magnetic resonance angiography indicates carotid plaques at high risk for cerebral embolism during stenting.
Stroke; a journal of cerebral circulation 2011;42(11):3132-7.
2011: Kunio Satoh; Manabu Takamatsu; Nguyen Huy Binh; Kazuhiro Kobayashi; Masaya Nakashima; Masayuki Niwa; Akira Hara
Increase of galectin-3 expression in microglia by hyperthermia in delayed neuronal death of hippocampal CA1 following transient forebrain ischemia.
Neuroscience letters 2011;504(3):199-203.
2011: Yuichiro Hatano; Suphot Phutthaphadoong; Yasuhiro Yamada; Hitomi Aoki; Kazuya Hata; Akira Hara
Genetic ablation of a candidate tumor suppressor gene, Rest, does not promote mouse colon carcinogenesis.
Cancer science 2011;102(9):1659-64.
2011: Hitomi Aoki; Akira Hara; Tsutomu Motohashi; Takahiro Kunisada
Protective effect of Kit signaling for melanocyte stem cells against radiation-induced genotoxic stress.
The Journal of investigative dermatology 2011;131(9):1906-15.
2011: Satoshi Endo; Anna Fujita; Urmi Dhagat; Ossama El-Kabbani; Tsukasa Kuragano; Toshiyuki Matsunaga; Midori Soda; Krithika Sundaram; Kazuo Tajima; Akira Hara
Activation of aldo-keto reductase family member 1B14 (AKR1B14) by bile acids: Activation mechanism and bile acid-binding site.
Biochimie 2011;93(9):1476-86.
2011: Toshiyuki Matsunaga; Yuhki Shinoda; Yukari Inoue; Yuki Shimizu; Mariko Haga; Satoshi Endo; Ossama El-Kabbani; Akira Hara
Aldo-keto reductase 1C15 as a quinone reductase in rat endothelial cell: its involvement in redox cycling of 9,10-phenanthrenequinone.
Free radical research 2011;45(7):848-57.
2011: Toshiyuki Matsunaga; Yuhki Shinoda; Yukari Inoue; Satoshi Endo; Ossama El-Kabbani; Akira Hara
Protective effect of rat aldo-keto reductase (AKR1C15) on endothelial cell damage elicited by 4-hydroxy-2-nonenal.
Chemico-biological interactions 2011;191(1-3):364-70.
2011: Mayuko Takemura; Satoshi Endo; Toshiyuki Matsunaga; Midori Soda; Hai-Tao Zhao; Ossama El-Kabbani; Kazuo Tajima; Munekazu Iinuma; Akira Hara
Selective inhibition of the tumor marker aldo-keto reductase family member 1B10 by oleanolic acid.
Journal of natural products 2011;74(5):1201-6.
2011: Kiyofumi Yamada; Shinichi Yoshimura; Masanori Kawasaki; Yukiko Enomoto; Takahiko Asano; Akira Hara; Shinya Minatoguchi; Toru Iwama
Embolic complications after carotid artery stenting or carotid endarterectomy are associated with tissue characteristics of carotid plaques evaluated by magnetic resonance imaging.
Atherosclerosis 2011;215(2):399-404.
2011: Kunio Satoh; Masayuki Niwa; Wael Goda; Nguyen Huy Binh; Masaya Nakashima; Manabu Takamatsu; Akira Hara
Galectin-3 expression in delayed neuronal death of hippocampal CA1 following transient forebrain ischemia, and its inhibition by hypothermia.
Brain research 2011;1382():266-74.
2011: Hitomi Aoki; Akira Hara; Tsutomu Motohashi; Masatake Osawa; Takahiro Kunisada
Functionally distinct melanocyte populations revealed by reconstitution of hair follicles in mice.
Pigment cell & melanoma research 2011;24(1):125-35.
2011: Masafumi Ohashi; En Shu; Masataka Tokuzumi; Kei Fujioka; Tatsuo Ishizuka; Akira Hara; Manabu Fujimoto; Kenzo Kaji; Mariko Seishima
Anti-p155/140 antibody-positive dermatomyositis with metastasis originating from an unknown site.
Acta dermato-venereologica 2011;91(1):84-5.
2011: Iori Takigami; Takatoshi Ohno; Yukio Kitade; Akira Hara; Akihito Nagano; Gou Kawai; Mitsuru Saitou; Aya Matsuhashi; Kazunari Yamada; Katsuji Shimizu
Synthetic siRNA targeting the breakpoint of EWS/Fli-1 inhibits growth of Ewing sarcoma xenografts in a mouse model.
International journal of cancer. Journal international du cancer 2011;128(1):216-26.
2010: Satoshi Endo; Toshiyuki Matsunaga; Tsukasa Kuragano; Satoshi Ohno; Yukio Kitade; Kazuo Tajima; Ossama El-Kabbani; Akira Hara
Properties and tissue distribution of a novel aldo-keto reductase encoding in a rat gene (Akr1b10).
Archives of biochemistry and biophysics 2010;503(2):230-7.
2010: Toshiyuki Matsunaga; Yoshitaka Tsuji; Kairyu Kaai; Saki Kohno; Renzo Hirayama; David H Alpers; Tsugikazu Komoda; Akira Hara
Toxicity against gastric cancer cells by combined treatment with 5-fluorouracil and mitomycin c: implication in oxidative stress.
Cancer chemotherapy and pharmacology 2010;66(3):517-26.
2010: Akira Hara; Ayako Taguchi; Hitomi Aoki; Yuichiro Hatano; Masayuki Niwa; Yasuhiro Yamada; Takahiro Kunisada
Folate antagonist, methotrexate induces neuronal differentiation of human embryonic stem cells transplanted into nude mouse retina.
Neuroscience letters 2010;477(3):138-43.
2010: Akihito Nagano; Takatoshi Ohno; Katsuji Shimizu; Akira Hara; Takatoshi Yamamoto; Gou Kawai; Mitsuru Saitou; Iori Takigami; Aya Matsuhashi; Kazunari Yamada; Yoshifumi Takei
EWS/Fli-1 chimeric fusion gene upregulates vascular endothelial growth factor-A.
International journal of cancer. Journal international du cancer 2010;126(12):2790-8.
2010: Satoshi Endo; Toshiyuki Matsunaga; Kazuo Kuwata; Hai-Tao Zhao; Ossama El-Kabbani; Yukio Kitade; Akira Hara
Chromene-3-carboxamide derivatives discovered from virtual screening as potent inhibitors of the tumour maker, AKR1B10.
Bioorganic & medicinal chemistry 2010;18(7):2485-90.
2010: Hiroyasu Sakai; Yasuhiro Yamada; Masahito Shimizu; Kuniaki Saito; Hisataka Moriwaki; Akira Hara
Genetic ablation of Tnfalpha demonstrates no detectable suppressive effect on inflammation-related mouse colon tumorigenesis.
Chemico-biological interactions 2010;184(3):423-30.
2010: Toshiyuki Matsunaga; Marina Arakaki; Tetsuro Kamiya; Mariko Haga; Satoshi Endo; Ossama El-Kabbani; Akira Hara
Nitric oxide mitigates apoptosis in human endothelial cells induced by 9,10-phenanthrenequinone: role of proteasomal function.
Toxicology 2010;268(3):191-7.
2010: Yasuhiro Yamada; Hitomi Aoki; Takahiro Kunisada; Akira Hara
Rest promotes the early differentiation of mouse ESCs but is not required for their maintenance.
Cell stem cell 2010;6(1):10-5.
2010: Satoshi Endo; Toshiyuki Matsunaga; Anna Fujita; Kazuo Tajima; Ossama El-Kabbani; Akira Hara
Rat aldose reductase-like protein (AKR1B14) efficiently reduces the lipid peroxidation product 4-oxo-2-nonenal.
Biological & pharmaceutical bulletin 2010;33(11):1886-90.
2010: Satoshi Endo; Toshiyuki Matsunaga; Midori Soda; Kazuo Tajima; Hi-Tai Zhao; Ossama El-Kabbani; Akira Hara
Selective inhibition of the tumor marker AKR1B10 by antiinflammatory N-phenylanthranilic acids and glycyrrhetic acid.
Biological & pharmaceutical bulletin 2010;33(5):886-90.
2010: Suphot Phutthaphadoong; Yasuhiro Yamada; Akihiro Hirata; Hiroyuki Tomita; Akira Hara; Pornngarm Limtrakul; Teruaki Iwasaki; Hiroshi Kobayashi; Hideki Mori
Chemopreventive effect of fermented brown rice and rice bran (FBRA) on the inflammation-related colorectal carcinogenesis in ApcMin/+ mice.
Oncology reports 2010;23(1):53-9.
2009: Toshiyuki Matsunaga; Satoshi Endo; Midori Soda; Hai-Tao Zhao; Ossama El-Kabbani; Kazuo Tajima; Akira Hara
Potent and selective inhibition of the tumor marker AKR1B10 by bisdemethoxycurcumin: probing the active site of the enzyme with molecular modeling and site-directed mutagenesis.
Biochemical and biophysical research communications 2009;389(1):128-32.
2009: Seiji Baba; Akira Hara; Keizo Kato; Nguyen Khanh Long; Yuichiro Hatano; Masashi Kimura; Yukio Okano; Yasuhiro Yamada; Toshiyuki Shibata
Aberrant promoter hypermethylation of the CHFR gene in oral squamous cell carcinomas.
Oncology reports 2009;22(5):1173-9.
2009: Toshiyuki Matsunaga; Marina Arakaki; Tetsuro Kamiya; Satoshi Endo; Ossama El-Kabbani; Akira Hara
Involvement of an aldo-keto reductase (AKR1C3) in redox cycling of 9,10-phenanthrenequinone leading to apoptosis in human endothelial cells.
Chemico-biological interactions 2009;181(1):52-60.
2009: Hitomi Aoki; Akira Hara; Masayuki Niwa; Yasuhiro Yamada; Takahiro Kunisada
In vitro and in vivo differentiation of human embryonic stem cells into retina-like organs and comparison with that from mouse pluripotent epiblast stem cells.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(9):2266-79.
2009: Masayuki Niwa; Akira Hara; Ayako Taguchi; Hitomi Aoki; Osamu Kozawa; Hideki Mori
Spatiotemporal expression of Hsp20 and its phosphorylation in hippocampal CA1 pyramidal neurons after transient forebrain ischemia.
Neurological research 2009;31(7):721-7.
2009: Hitomi Aoki; Yasuhiro Yamada; Akira Hara; Takahiro Kunisada
Two distinct types of mouse melanocyte: differential signaling requirement for the maintenance of non-cutaneous and dermal versus epidermal melanocytes.
Development (Cambridge, England) 2009;136(15):2511-21.
2009: Satoshi Endo; Toshiyuki Matsunaga; Hiroaki Mamiya; Chisato Ohta; Midori Soda; Yukio Kitade; Kazuo Tajima; Hai-Tao Zhao; Ossama El-Kabbani; Akira Hara
Kinetic studies of AKR1B10, human aldose reductase-like protein: endogenous substrates and inhibition by steroids.
Archives of biochemistry and biophysics 2009;487(1):1-9.
2009: Seiji Baba; Yasuhiro Yamada; Yuichiro Hatano; Yasuo Miyazaki; Hideki Mori; Toshiyuki Shibata; Akira Hara
Global DNA hypomethylation suppresses squamous carcinogenesis in the tongue and esophagus.
Cancer science 2009;100(7):1186-91.
2009: Satoshi Nemoto; Mitsuhiro Nakamura; Yosuke Osawa; Saki Kono; Yoshinori Itoh; Yukio Okano; Takashi Murate; Akira Hara; Hiroshi Ueda; Yoshinori Nozawa; Yoshiko Banno
Sphingosine kinase isoforms regulate oxaliplatin sensitivity of human colon cancer cells through ceramide accumulation and Akt activation.
The Journal of biological chemistry 2009;284(16):10422-32.
2009: Satoshi Endo; Toshiyuki Matsunaga; Hiroaki Mamiya; Akira Hara; Yukio Kitade; Kazuo Tajima; Ossama El-Kabbani
Characterization of a rat NADPH-dependent aldo-keto reductase (AKR1B13) induced by oxidative stress.
Chemico-biological interactions 2009;178(1-3):151-7.
2009: Masato Hoshi; Kuniaki Saito; Yuki Murakami; Ayako Taguchi; Hidetsugu Fujigaki; Ryo Tanaka; Masao Takemura; Hiroyasu Ito; Akira Hara; Mitsuru Seishima
Marked increases in hippocampal neuron indoleamine 2, 3-dioxygenase via IFN-gamma-independent pathway following transient global ischemia in mouse.
Neuroscience research 2009;63(3):194-8.
2009: Suphot Phutthaphadoong; Yasuhiro Yamada; Akihiko Hirata; Hiroyuki Tomita; Ayako Taguchi; Akira Hara; Porn-Ngam Limtrakul; Teruaki Iwasaki; Hiroshi Kobayashi; Hideki Mori
Chemopreventive effects of fermented brown rice and rice bran against 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced lung tumorigenesis in female A/J mice.
Oncology reports 2009;21(2):321-7.
2009: Naoki Iwamoto; Hiroyasu Ito; Kazuki Ando; Tetsuya Ishikawa; Akira Hara; Ayako Taguchi; Kuniaki Saito; Masao Takemura; Michio Imawari; Hisataka Moriwaki; Mitsuru Seishima
Upregulation of indoleamine 2,3-dioxygenase in hepatocyte during acute hepatitis caused by hepatitis B virus-specific cytotoxic T lymphocytes in vivo.
Liver international : official journal of the International Association for the Study of the Liver 2009;29(2):277-83.
2009: Satoshi Endo; Satoshi Maeda; Toshiyuki Matsunaga; Urmi Dhagat; Ossama El-Kabbani; Nobutada Tanaka; Kazuo T Nakamura; Kazuo Tajima; Akira Hara
Molecular determinants for the stereospecific reduction of 3-ketosteroids and reactivity towards all-trans-retinal of a short-chain dehydrogenase/reductase (DHRS4).
Archives of biochemistry and biophysics 2009;481(2):183-90.
2008: Satoshi Endo; Toshiyuki Matsunaga; Yukio Kitade; Satoshi Ohno; Kazuo Tajima; Ossama El-Kabbani; Akira Hara
Human carbonyl reductase 4 is a mitochondrial NADPH-dependent quinone reductase.
Biochemical and biophysical research communications 2008;377(4):1326-30.
2008: Nguyen Khanh Long; Keizo Kato; Tomomi Yamashita; Hiroki Makita; Makoto Toida; Daijiro Hatakeyama; Akira Hara; Hideki Mori; Toshiyuki Shibata
Hypermethylation of the RECK gene predicts poor prognosis in oral squamous cell carcinomas.
Oral oncology 2008;44(11):1052-8.
2008: Hitomi Aoki; Akira Hara; Tsutomu Motohashi; Huayue Chem; Takahiro Kunisada
Iris as a recipient tissue for pigment cells: organized in vivo differentiation of melanocytes and pigmented epithelium derived from embryonic stem cells in vitro.
Developmental dynamics : an official publication of the American Association of Anatomists 2008;237(9):2394-404.
2008: Kanefusa Kato; N K Long; H Makita; Makoto Toida; Tomomi Yamashita; Daijiro Hatakeyama; Akira Hara; Hideki Mori; Toshiyuki Shibata
Effects of green tea polyphenol on methylation status of RECK gene and cancer cell invasion in oral squamous cell carcinoma cells.
British journal of cancer 2008;99(4):647-54.
2008: Akira Hara; Hitomi Aoki; Ayako Taguchi; Masayuki Niwa; Yasuhiro Yamada; Takahiro Kunisada; Hideki Mori
Neuron-like differentiation and selective ablation of undifferentiated embryonic stem cells containing suicide gene with Oct-4 promoter.
Stem cells and development 2008;17(4):619-27.
2008: Ayako Taguchi; Akira Hara; Kuniaki Saito; Masato Hoshi; Masayuki Niwa; Mitsuru Seishima; Hideki Mori
Localization and spatiotemporal expression of IDO following transient forebrain ischemia in gerbils.
Brain research 2008;1217():78-85.
2008: Isao Hozumi; Junko S Suzuki; Hiroaki Kanazawa; Akira Hara; Masanao Saio; Takashi Inuzuka; Shinichi Miyairi; Akira Naganuma; Chiharu Tohyama
Metallothionein-3 is expressed in the brain and various peripheral organs of the rat.
Neuroscience letters 2008;438(1):54-8.
2008: Takeru Oyama; Yasuhiro Yamada; Kazuya Hata; Hiroyuki Tomita; Akihiro Hirata; Hongqiang Sheng; Akira Hara; Hitomi Aoki; Takahiro Kunisada; Satoshi Yamashita; Hideki Mori
Further upregulation of beta-catenin/Tcf transcription is involved in the development of macroscopic tumors in the colon of ApcMin/+ mice.
Carcinogenesis 2008;29(3):666-72.
2008: Yoshiko Banno; Satoshi Nemoto; Masashi Murakami; Masashi Kimura; Yoshihito Ueno; Kenji Ohguchi; Akira Hara; Yukio Okano; Yukio Kitade; Minoru Onozuka; Takashi Murate; Yoshinori Nozawa
Depolarization-induced differentiation of PC12 cells is mediated by phospholipase D2 through the transcription factor CREB pathway.
Journal of neurochemistry 2008;104(5):1372-86.
2008: Hitomi Aoki; Akira Hara; Masayuki Niwa; Tsutomu Motohashi; Takashi Suzuki; Takahiro Kunisada
Transplantation of cells from eye-like structures differentiated from embryonic stem cells in vitro and in vivo regeneration of retinal ganglion-like cells.
Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv für klinische und experimentelle Ophthalmologie 2008;246(2):255-65.
2008: Hiroyuki Tomita; Toshiya Kuno; Yasuhiro Yamada; Takeru Oyama; Nami Asano; Yasuo Miyazaki; Seiji Baba; Ayako Taguchi; Akira Hara; Teruaki Iwasaki; Hiroshi Kobayashi; Hideki Mori
Preventive effect of fermented brown rice and rice bran on N-methyl-N'-nitro-N-nitrosoguanidine-induced gastric carcinogenesis in rats.
Oncology reports 2008;19(1):11-5.
2008: Yasuo Miyazaki; Akira Hara; Keizo Kato; Takeru Oyama; Yasuhiro Yamada; Hideki Mori; Toshiyuki Shibata
The effect of hypoxic microenvironment on matrix metalloproteinase expression in xenografts of human oral squamous cell carcinoma.
International journal of oncology 2008;32(1):145-51.
2007: Naoki Oka; Akio Soeda; Akihito Inagaki; Masafumi Onodera; Hidekazu Maruyama; Akira Hara; Takahiro Kunisada; Hideki Mori; Toru Iwama
VEGF promotes tumorigenesis and angiogenesis of human glioblastoma stem cells.
Biochemical and biophysical research communications 2007;360(3):553-9.
2007: Akira Hara; Ayako Taguchi; Masayuki Niwa; Hitomi Aoki; Yasuhiro Yamada; Hidenori Ito; Koh-ichi Nagata; Takahiro Kunisada; Hideki Mori
Localization of septin 8 in murine retina, and spatiotemporal expression of septin 8 in a murine model of photoreceptor cell degeneration.
Neuroscience letters 2007;423(3):205-10.
2007: Hiroyuki Tomita; Yasuhiro Yamada; Takeru Oyama; Kazuya Hata; Yoshinobu Hirose; Akira Hara; Takahiro Kunisada; Yasuyuki Sugiyama; Yosuke Adachi; Heinz Linhart; Hideki Mori
Development of gastric tumors in Apc(Min/+) mice by the activation of the beta-catenin/Tcf signaling pathway.
Cancer research 2007;67(9):4079-87.
2007: Hitomi Aoki; Akira Hara; Masayuki Niwa; Tsutomu Motohashi; Takashi Suzuki; Takahiro Kunisada
An in vitro mouse model for retinal ganglion cell replacement therapy using eye-like structures differentiated from ES cells.
Experimental eye research 2007;84(5):868-75.
2007: HongQiang Sheng; Yoshinobu Hirose; Kazuya Hata; Qiao Zheng; Toshiya Kuno; Nami Asano; Yasuhiro Yamada; Akira Hara; Toshihiko Osawa; Hideki Mori
Modifying effect of dietary sesaminol glucosides on the formation of azoxymethane-induced premalignant lesions of rat colon.
Cancer letters 2007;246(1-2):63-8.
2007: Huilan Zhi; Yasuhiro Yamada; Yoshinobu Hirose; Keizo Kato; Hongqiang Sheng; Qiao Zheng; Takeru Oyama; Nami Asano; Toshiya Kuno; Akira Hara; Hideki Mori
Effect of 2-(carboxyphenyl) retinamide and genistein on the formation of early lesions in 1,2-dimethylhydrazine-induced colon carcinogenesis in rats.
Asian Pacific journal of cancer prevention : APJCP 2007;8(1):33-8.
2006: Masayuki Niwa; Koichi Hotta; Akira Hara; Kouseki Hirade; Hidenori Ito; Kanefusa Kato; Osamu Kozawa
TNF-alpha decreases hsp 27 in human blood mononuclear cells: involvement of protein kinase c.
Life sciences 2006;80(3):181-6.
2006: Keizo Kato; Akira Hara; Toshiya Kuno; Hideki Mori; Tomomi Yamashita; Makoto Toida; Toshiyuki Shibata
Aberrant promoter hypermethylation of p16 and MGMT genes in oral squamous cell carcinomas and the surrounding normal mucosa.
Journal of cancer research and clinical oncology 2006;132(11):735-43.
2006: Akira Hara; Masayuki Niwa; Hitomi Aoki; Masako Kumada; Takahiro Kunisada; Takeru Oyama; Tetsuya Yamamoto; Osamu Kozawa; Hideki Mori
A new model of retinal photoreceptor cell degeneration induced by a chemical hypoxia-mimicking agent, cobalt chloride.
Brain research 2006;1109(1):192-200.
2006: Kazuya Hata; Takuji Tanaka; Hiroyuki Kohno; Rikako Suzuki; Sheng Hong Qiang; Yasuhiro Yamada; Takeshi Oyama; Toshiya Kuno; Yoshinobu Hirose; Akira Hara; Hideki Mori
beta-Catenin-accumulated crypts in the colonic mucosa of juvenile ApcMin/+ mice.
Cancer letters 2006;239(1):123-8.
2006: Kazuya Hata; Takuji Tanaka; Hiroyuki Kohno; Rikako Suzuki; Sheng Hong Qiang; Toshiya Kuno; Yoshinobu Hirose; Akira Hara; Hideki Mori
Lack of enhancing effects of degraded lambda-carrageenan on the development of beta-catenin-accumulated crypts in male DBA/2J mice initiated with azoxymethane.
Cancer letters 2006;238(1):69-75.
2006: Akira Hara; Masayuki Niwa; Masako Kumada; Hitomi Aoki; Takahiro Kunisada; Takeru Oyama; Tetsuya Yamamoto; Osamu Kozawa; Hideki Mori
Intraocular injection of folate antagonist methotrexate induces neuronal differentiation of embryonic stem cells transplanted in the adult mouse retina.
Brain research 2006;1085(1):33-42.
2006: Hitomi Aoki; Akira Hara; Shinichi Nakagawa; Tsutomu Motohashi; Mariko Hirano; Yoshiko Takahashi; Takahiro Kunisada
Embryonic stem cells that differentiate into RPE cell precursors in vitro develop into RPE cell monolayers in vivo.
Experimental eye research 2006;82(2):265-74.
2005: Shigeyuki Sugie; Pham Quang Vinh; K M Wahidur Rahman; Jun Ushida; Hiroyuki Kohno; Rikako Suzuki; Akira Hara; Le Bach Quang; Takuji Tanaka; Hideki Mori
Suppressive effect of 1,4-phenylene diisothiocyanate on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.
International journal of cancer. Journal international du cancer 2005;117(4):524-30.
2005: Akira Hara; Keiko Sakata; Yasuhiro Yamada; Toshiya Kuno; Nami Kitaori; Takeru Oyama; Yoshinobu Hirose; Akira Murakami; Takuji Tanaka; Hideki Mori
Suppression of beta-catenin mutation by dietary exposure of auraptene, a citrus antioxidant, in N,N-diethylnitrosamine-induced hepatocellular carcinomas in rats.
Oncology reports 2005;14(2):345-51.
2005: Hideki Mori; Kazuya Hata; Yasuhiro Yamada; Toshiya Kuno; Akira Hara
Significance and role of early-lesions in experimental colorectal carcinogenesis.
Chemico-biological interactions 2005;155(1-2):1-9.
2005: Shigeyuki Sugie; Masami Ohnishi; Jun Ushida; Tomohiro Yamamoto; Akira Hara; Akihiro Koide; Yukio Mori; Hiroyuki Kohno; Rikako Suzuki; Takuji Tanaka; Keiji Wakabayashi; Hideki Mori
Effect of alpha-naphthyl isothiocyanate on 2-amino-3-methylimidazo[4,5-b]pyridine (PhIP)-induced mammary carcinogenesis in rats.
International journal of cancer. Journal international du cancer 2005;115(3):346-50.
2005: Yuki Murakami; Kuniaki Saito; Akira Hara; Yuyan Zhu; Kaori Sudo; Masayuki Niwa; Hidehiko Fujii; Hisayasu Wada; Hiroshi Ishiguro; Hideki Mori; Mitsuru Seishima
Increases in tumor necrosis factor-alpha following transient global cerebral ischemia do not contribute to neuron death in mouse hippocampus.
Journal of neurochemistry 2005;93(6):1616-22.
2005: Keizo Kato; Akira Hara; Toshiya Kuno; Nami Kitaori; Zhi Huilan; Hideki Mori; Makoto Toida; Toshiyuki Shibata
Matrix metalloproteinases 2 and 9 in oral squamous cell carcinomas: manifestation and localization of their activity.
Journal of cancer research and clinical oncology 2005;131(6):340-6.
2005: Masanori Kawasaki; Yoko Ito; Haruko Yokoyama; Masazumi Arai; Genzou Takemura; Akira Hara; Yoshiro Ichiki; Hisato Takatsu; Shinya Minatoguchi; Hisayoshi Fujiwara
Assessment of arterial medial characteristics in human carotid arteries using integrated backscatter ultrasound and its histological implications.
Atherosclerosis 2005;180(1):145-54.
2005: Yoshiko Banno; Kenji Ohguchi; Naoki Matsumoto; Masahiro Koda; Masashi Ueda; Akira Hara; Ivan Dikic; Yoshinori Nozawa
Implication of phospholipase D2 in oxidant-induced phosphoinositide 3-kinase signaling via Pyk2 activation in PC12 cells.
The Journal of biological chemistry 2005;280(16):16319-24.
2005: Koujiro Yoshida; Takuji Tanaka; Yoshinobu Hirose; Fumio Yamaguchi; Hiroyuki Kohno; Makoto Toida; Akira Hara; Shigeyuki Sugie; Toshiyuki Shibata; Hideki Mori
Dietary garcinol inhibits 4-nitroquinoline 1-oxide-induced tongue carcinogenesis in rats.
Cancer letters 2005;221(1):29-39.
2005: Masako Kumada; Masayuki Niwa; Akira Hara; Hiroyuki Matsuno; Hideki Mori; Shigeru Ueshima; Osamu Matsuo; Tetsuya Yamamoto; Osamu Kozawa
Tissue type plasminogen activator facilitates NMDA-receptor-mediated retinal apoptosis through an independent fibrinolytic cascade.
Investigative ophthalmology & visual science 2005;46(4):1504-7.
2004: Toshiya Kuno; Yoshinobu Hirose; Kazuya Hata; Keizou Kato; Sheng Hong Qiang; Nami Kitaori; Akira Hara; Teruaki Iwasaki; Teruki Yoshimura; Keiji Wada; Hiroshi Kobayashi; Hideki Mori
Preventive effect of fermented brown rice and rice bran on N-nitrosomethylbenzylamine-induced esophageal tumorigenesis in rats.
International journal of oncology 2004;25(6):1809-15.
2004: Masako Kumada; Masayuki Niwa; Xiaodan Wang; Hiroyuki Matsuno; Akira Hara; Hideki Mori; Osamu Matsuo; Tetsuya Yamamoto; Osamu Kozawa
Endogenous tissue type plasminogen activator facilitates NMDA-induced retinal damage.
Toxicology and applied pharmacology 2004;200(1):48-53.
2004: Akira Hara; Yoshinobu Hirose; Hideki Mori; Humihiko Iwao; Tatsuo Kato; Yasuhiro Kusuhara
Cytopathologic and genetic diagnosis of pulmonary amebiasis: a case report.
Acta cytologica 2004;48(4):547-50.
2004: Akira Hara; Masayuki Niwa; Masako Kumada; Nami Kitaori; Tetsuya Yamamoto; Osamu Kozawa; Hideki Mori
Fragmented DNA transport in dendrites of retinal neurons during apoptotic cell death.
Brain research 2004;1007(1-2):183-7.
2004: Kazuya Hata; Yasuhiro Yamada; Toshiya Kuno; Yoshinobu Hirose; Akira Hara; Sheng Hong Qiang; Hideki Mori
Tumor formation is correlated with expression of beta-catenin-accumulated crypts in azoxymethane-induced colon carcinogenesis in mice.
Cancer science 2004;95(4):316-20.
2004: Akira Hara; Masayuki Niwa; Takahiro Kunisada; Naoko Yoshimura; Masaki Katayama; Osamu Kozawa; Hideki Mori
Embryonic stem cells are capable of generating a neuronal network in the adult mouse retina.
Brain research 2004;999(2):216-21.
2004: Kazumi Maeda; Akira Sawada; Masayuki Matsubara; Yoshiyuki Nakai; Akira Hara; Tetsuya Yamamoto
A novel neuroprotectant against retinal ganglion cell damage in a glaucoma model and an optic nerve crush model in the rat.
Investigative ophthalmology & visual science 2004;45(3):851-6.
2004: Keiko Sakata; Akira Hara; Yoshinobu Hirose; Yasuhiro Yamada; Toshiya Kuno; Masaki Katayama; Koujiro Yoshida; Qiao Zheng; Akira Murakami; Hajime Ohigashi; Kohei Ikemoto; Koichi Koshimizu; Takuji Tanaka; Hideki Mori
Dietary supplementation of the citrus antioxidant auraptene inhibits N,N-diethylnitrosamine-induced rat hepatocarcinogenesis.
Oncology 2004;66(3):244-52.
2003: Toshiya Kuno; Yoshinobu Hirose; Yasuhiro Yamada; Koujirou Yoshida; Zheng Qiao; Masaki Katayama; Keiko Sakata; Akira Hara; Shigeyuki Sugie; Hideki Mori
Promoting effects of high-fat corn oil and high-fat mixed lipid diets on 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis in F344 rats.
Oncology reports 2003;10(3):699-703.
2003: Masayuki Niwa; Koichi Hotta; Yutaka Kanamori; Daijiro Hatakeyama; Kouseki Hirade; Masaki Katayama; Akira Hara; Hideki Mori; Hidenori Ito; Kanefusa Kato; Hiroyuki Matsuno; Toshihiko Uematsu; Osamu Kozawa
Involvement of p38 mitogen-activated protein kinase in heat shock protein 27 induction in human neutrophils.
European journal of pharmacology 2003;466(3):245-53.
2003: Masaki Katayama; Akira Hara; Yoshinobu Hirose; Yasuhiro Yamada; Toshiya Kuno; Keiko Sakata; Takamitsu Morioka; Morihiko Inamine; Chiken Shibuya; Hideki Mori; Naoki Yoshimi
Carcinoid tumor in the female urethral orifice: rare case report and a review of the literature.
Pathology international 2003;53(2):102-5.
2003: Yoshiko Banno; Yoh Takuwa; Momoko Yamada; Noriko Takuwa; Kenji Ohguchi; Akira Hara; Yoshinori Nozawa
Involvement of phospholipase D in insulin-like growth factor-I-induced activation of extracellular signal-regulated kinase, but not phosphoinositide 3-kinase or Akt, in Chinese hamster ovary cells.
The Biochemical journal 2003;369(Pt 2):363-8.
2003: Yasuhiro Yamada; Takeru Oyama; Yoshinobu Hirose; Akira Hara; Shigeyuki Sugie; Koujiro Yoshida; Naoki Yoshimi; Hideki Mori
beta-Catenin mutation is selected during malignant transformation in colon carcinogenesis.
Carcinogenesis 2003;24(1):91-7.
2002: Yasuhiro Yamada; Kazuya Hata; Yoshinobu Hirose; Akira Hara; Shigeyuki Sugie; Toshiya Kuno; Naoki Yoshimi; Takuji Tanaka; Hideki Mori
Microadenomatous lesions involving loss of Apc heterozygosity in the colon of adult Apc(Min/+) mice.
Cancer research 2002;62(22):6367-70.
2002: Xiaodan Wang; Masayuki Niwa; Akira Hara; Hiroyuki Matsuno; Kazuhide Kawase; Osamu Kozawa; Hideki Mow; Toshihiko Uematsu
Neuronal degradation in mouse retina after a transient ischemia and protective effect of hypothermia.
Neurological research 2002;24(7):730-5.
2002: Hiroyuki Matsuno; Osamu Kozawa; Naoki Yoshimi; Shigeru Akamatsu; Akira Hara; Hideki Mori; Kiyotaka Okada; Shigeru Ueshima; Osamu Matsuo; Toshihiko Uematsu
Lack of alpha2-antiplasmin promotes pulmonary heart failure via overrelease of VEGF after acute myocardial infarction.
Blood 2002;100(7):2487-93.
2002: Hideki Mori; Yasuhiro Yamada; Yoshinobu Hirose; Toshiya Kuno; M Katayama; Keiko Sakata; K Yoshida; Shigeyuki Sugie; Akira Hara; Naoki Yoshimi
Chemoprevention of large bowel carcinogenesis; the role of control of cell proliferation and significance of beta-catenin-accumulated crypts as a new biomarker.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2002;11 Suppl 2():S71-5.
2002: Toshiya Kuno; Yasuhiro Yamada; Yoshinobu Hirose; Masaki Katayama; Keiko Sakata; Akira Hara; Shigetoyo Saji; Hideki Mori
Induction of apoptosis by sulindac in azoxymethane-induced possible colonic premalignant lesions in rats.
Japanese journal of cancer research : Gann 2002;93(3):242-6.
2002: Pham Quang Vinh; Shigeyuki Sugie; Takuji Tanaka; Akira Hara; Yasuhiro Yamada; Masaki Katayama; Takashi Deguchi; Hideki Mori
Chemopreventive effects of a flavonoid antioxidant silymarin on N-butyl-N-(4-hydroxybutyl)nitrosamine-induced urinary bladder carcinogenesis in male ICR mice.
Japanese journal of cancer research : Gann 2002;93(1):42-9.
2001: Koichi Hotta; Masayuki Niwa; Akira Hara; T Ohno; X Wang; Hiroyuki Matsuno; Osamu Kozawa; Hidenori Ito; Kanefusa Kato; T Otsuka; N Matsui; Toshihiko Uematsu
The loss of susceptibility to apoptosis in exudated tissue neutrophils is associated with their nuclear factor-kappa B activation.
European journal of pharmacology 2001;433(1):17-27.
2001: Katsuhiko Hayashi; Ryuichi Morishita; H Nakagami; Shinichi Yoshimura; Akira Hara; Kunio Matsumoto; Toshikazu Nakamura; Toshio Ogihara; Yasufumi Kaneda; Noboru Sakai
Gene therapy for preventing neuronal death using hepatocyte growth factor: in vivo gene transfer of HGF to subarachnoid space prevents delayed neuronal death in gerbil hippocampal CA1 neurons.
Gene therapy 2001;8(15):1167-73.
2001: Yasuhiro Yamada; Naoki Yoshimi; Yoshinobu Hirose; Akira Hara; Masahito Shimizu; Toshiya Kuno; Masaki Katayama; Zheng Qiao; Hideki Mori
Suppression of occurrence and advancement of beta-catenin-accumulated crypts, possible premalignant lesions of colon cancer, by selective cyclooxygenase-2 inhibitor, celecoxib.
Japanese journal of cancer research : Gann 2001;92(6):617-23.
2001: Masayuki Niwa; Akira Hara; T Iwai; S Wang; K Hotta; Hideki Mori; Toshihiko Uematsu
Caspase activation as an apoptotic evidence in the gerbil hippocampal CA1 pyramidal cells following transient forebrain ischemia.
Neuroscience letters 2001;300(2):103-6.
2001: M Shimizu; Akira Hara; Masataka Okuno; H Matsuno; K Okada; Shigeru Ueshima; Osamu Matsuo; M Niwa; Kuniharu Akita; Yasuhiro Yamada; N Yoshimi; T Uematsu; Soichi Kojima; Scott L Friedman; Hisataka Moriwaki; H Mori
Mechanism of retarded liver regeneration in plasminogen activator-deficient mice: impaired activation of hepatocyte growth factor after Fas-mediated massive hepatic apoptosis.
Hepatology (Baltimore, Md.) 2001;33(3):569-76.
2001: Naoki Yoshimi; K Matsunaga; Masaki Katayama; Yasuhiro Yamada; Toshiya Kuno; Zheng Qiao; Akira Hara; J Yamahara; Hideki Mori
The inhibitory effects of mangiferin, a naturally occurring glucosylxanthone, in bowel carcinogenesis of male F344 rats.
Cancer letters 2001;163(2):163-70.
2001: Hirohito Yano; Akira Hara; S Murase; Katsuhiko Hayashi; Hiromichi Ando; Jun Shinoda; Kuniyasu Shimokawa; Noboru Sakai
Expression of hepatocyte growth factor and matrix metalloproteinase-2 in human glioma.
Brain tumor pathology 2001;18(1):7-12.
2000: Masayuki Niwa; Akira Hara; Yutaka Kanamori; Daijiro Hatakeyama; Masanao Saio; T Takami; Hiroyuki Matsuno; Osamu Kozawa; Toshihiko Uematsu
Nuclear factor-kappaB activates dual inhibition sites in the regulation of tumor necrosis factor-alpha-induced neutrophil apoptosis.
European journal of pharmacology 2000;407(3):211-9.
2000: H Yano; Akira Hara; KV Takenaka; K Nakatani; Jun Shinoda; K Shimokawa; Naoki Yoshimi; Hideki Mori; Noboru Sakai
Differential expression of beta-catenin in human glioblastoma multiforme and normal brain tissue.
Neurological research 2000;22(7):650-6.
2000: Kunihiro Kawabata; T Yamamoto; Akira Hara; Masahito Shimizu; Yasuhiro Yamada; K Matsunaga; Takuji Tanaka; Hideki Mori
Modifying effects of ferulic acid on azoxymethane-induced colon carcinogenesis in F344 rats.
Cancer letters 2000;157(1):15-21.
2000: L Daugeliene; Masayuki Niwa; Akira Hara; Hiroyuki Matsuno; Tetsuya Yamamoto; Yoshiaki Kitazawa; Toshihiko Uematsu
Transient ischemic injury in the rat retina caused by thrombotic occlusion-thrombolytic reperfusion.
Investigative ophthalmology & visual science 2000;41(9):2743-7.
2000: H Yano; Akira Hara; Jun Shinoda; KV Takenaka; Naoki Yoshimi; Hideki Mori; Noboru Sakai
Immunohistochemical analysis of beta-catenin in N-ethyl-N-nitrosourea-induced rat gliomas: implications in regulation of angiogenesis.
Neurological research 2000;22(5):527-32.
2000: Yasuhiro Yamada; Naoki Yoshimi; Yoshinobu Hirose; Kunihiro Kawabata; K Matsunaga; Masahito Shimizu; Akira Hara; Hideki Mori
Frequent beta-catenin gene mutations and accumulations of the protein in the putative preneoplastic lesions lacking macroscopic aberrant crypt foci appearance, in rat colon carcinogenesis.
Cancer research 2000;60(13):3323-7.
2000: Kunihiro Kawabata; Takuji Tanaka; T Yamamoto; Akira Hara; Akira Murakami; Koichi Koshimizu; Hajime Ohigashi; G D Stoner; Hideki Mori
Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of auraptene.
Journal of experimental & clinical cancer research : CR 2000;19(1):45-52.
2000: T Iwai; Masayuki Niwa; Akira Hara; Hideki Mori; Toshihiko Uematsu; Noboru Sakai
DNA fragmentation in the CA2 sector of gerbil hippocampus following transient forebrain ischemia.
Brain research 2000;857(1-2):275-8.
2000: Akira Hara; Masayuki Niwa; T Iwai; H Yano; Yasuo Bunai; Toshihiko Uematsu; N Yoshimi; Hideki Mori
Increase of fragmented DNA transport in apical dendrites of gerbil CA1 pyramidal neurons following transient forebrain ischemia by mild hypothermia.
Neuroscience letters 2000;280(1):73-7.
2000: Kunihiro Kawabata; Takuji Tanaka; T Yamamoto; Jun Ushida; Akira Hara; Akira Murakami; Koichi Koshimizu; Hajime Ohigashi; G D Stoner; Hideki Mori
Suppression of N-nitrosomethylbenzylamine-induced rat esophageal tumorigenesis by dietary feeding of 1'-acetoxychavicol acetate.
Japanese journal of cancer research : Gann 2000;91(2):148-55.
2000: Hirohito Yano; Jun Shinoda; Akira Hara; Kuniyasu Shimokawa; Noboru Sakai
Chordoid meningioma.
Brain tumor pathology 2000;17(3):153-7.
2000: Hideki Mori; Kunihiro Kawabata; K Matsunaga; Jun Ushida; K Fujii; Akira Hara; Takuji Tanaka; H Murai
Chemopreventive effects of coffee bean and rice constituents on colorectal carcinogenesis.
BioFactors (Oxford, England) 2000;12(1-4):101-5.
2000: Masayuki Niwa; Osamu Kozawa; Hiroyuki Matsuno; Yutaka Kanamori; Akira Hara; Toshihiko Uematsu
Tumor necrosis factor-alpha-mediated signal transduction in human neutrophils: involvement of sphingomyelin metabolites in the priming effect of TNF-alpha on the fMLP-stimulated superoxide production.
Life sciences 2000;66(3):245-56.
2000: Akira Hara; Naoki Yoshimi; Yasuhiro Yamada; K Matsunaga; Kunihiro Kawabata; Shigeyuki Sugie; Hideki Mori
Effects of Fas-mediated liver cell apoptosis on diethylnitrosamine-induced hepatocarcinogenesis in mice.
British journal of cancer 2000;82(2):467-71.
1999: Masahito Shimizu; Naoki Yoshimi; Yasuhiro Yamada; K Matsunaga; Kunihiro Kawabata; Akira Hara; Hisataka Moriwaki; Hideki Mori
Suppressive effects of chlorogenic acid on N-methyl-N-nitrosourea-induced glandular stomach carcinogenesis in male F344 rats.
The Journal of toxicological sciences 1999;24(5):433-9.
1999: Kunihiro Kawabata; Takuji Tanaka; T Murakami; T Okada; H Murai; T Yamamoto; Akira Hara; Masahito Shimizu; Yasuhiro Yamada; K Matsunaga; Toshiya Kuno; Naoki Yoshimi; Shigeyuki Sugie; Hideki Mori
Dietary prevention of azoxymethane-induced colon carcinogenesis with rice-germ in F344 rats.
Carcinogenesis 1999;20(11):2109-15.
1999: Kunihiro Kawabata; Takuji Tanaka; S Honjo; M Kakumoto; Akira Hara; Hiroki Makita; Norichika Tatematsu; Jun Ushida; H Tsuda; Hideki Mori
Chemopreventive effect of dietary flavonoid morin on chemically induced rat tongue carcinogenesis.
International journal of cancer. Journal international du cancer 1999;83(3):381-6.
1999: Akira Hara; Masayuki Niwa; T Iwai; H Yano; M Nakashima; Yasuo Bunai; Toshihiko Uematsu; N Yoshimi; Hideki Mori
Failure of preventive effects of 2-deoxy-D-glucose on ischemia-induced gerbil hippocampal neuronal damage by induced hyperthermia.
Brain research 1999;840(1-2):167-70.
1999: Yasuhiro Yamada; Naoki Yoshimi; Shigeyuki Sugie; Masumi Suzui; K Matsunaga; Kunihiro Kawabata; Akira Hara; Hideki Mori
Beta-catenin (Ctnnb1) gene mutations in diethylnitrosamine (DEN)-induced liver tumors in male F344 rats.
Japanese journal of cancer research : Gann 1999;90(8):824-8.
1999: Takuji Tanaka; Kunihiro Kawabata; M Kakumoto; Hiroki Makita; Jun Ushida; S Honjo; Akira Hara; H Tsuda; Hideki Mori
Modifying effects of a flavonoid morin on azoxymethane-induced large bowel tumorigenesis in rats.
Carcinogenesis 1999;20(8):1477-84.
1999: Hideki Mori; Shigeyuki Sugie; Naoki Yoshimi; Akira Hara; Takuji Tanaka
Control of cell proliferation in cancer prevention.
Mutation research 1999;428(1-2):291-8.
1999: Akira Hara; Masayuki Niwa; T Iwai; M Nakashima; Yasuo Bunai; Toshihiko Uematsu; N Yoshimi; Hideki Mori
Neuronal apoptosis studied by a sequential TUNEL technique: a method for tract-tracing.
Brain research. Brain research protocols 1999;4(2):140-6.
1999: Masayuki Niwa; Akira Hara; Yutaka Kanamori; Hiroyuki Matsuno; Osamu Kozawa; Naoki Yoshimi; Hideki Mori; Toshihiko Uematsu
Inhibition of tumor necrosis factor-alpha induced neutrophil apoptosis by cyclic AMP: involvement of caspase cascade.
European journal of pharmacology 1999;371(1):59-67.
1999: Naoki Yoshimi; Masahito Shimizu; K Matsunaga; Yasuhiro Yamada; K Fujii; Akira Hara; Hideki Mori
Chemopreventive effect of N-(2-cyclohexyloxy-4-nitrophenyl)methane sulfonamide (NS-398), a selective cyclooxygenase-2 inhibitor, in rat colon carcinogenesis induced by azoxymethane.
Japanese journal of cancer research : Gann 1999;90(4):406-12.
1999: Masayuki Niwa; Akira Hara; T Iwai; M Nakashima; N Yoshimi; Hideki Mori; Toshihiko Uematsu
Prevention of ischemia-induced hippocampal neuronal damage by 2-deoxy-D-glucose in gerbils.
Life sciences 1999;64(18):PL193-8.
1998: Yoshiko Banno; M Kato; Akira Hara; Yoshinori Nozawa
Evidence for the presence of multiple forms of Sph kinase in human platelets.
The Biochemical journal 1998;335 ( Pt 2)():301-4.
1998: Akira Hara; Masayuki Niwa; T Iwai; M Nakashima; H Yano; Toshihiko Uematsu; N Yoshimi; Hideki Mori
Transport of fragmented DNA in apical dendrites of gerbil CA1 pyramidal neurons following transient forebrain ischemia.
Brain research 1998;806(2):274-7.
1998: Akira Hara; Masayuki Niwa; M Nakashima; T Iwai; Toshihiko Uematsu; N Yoshimi; Hideki Mori
Protective effect of apoptosis-inhibitory agent, N-tosyl-L-phenylalanyl chloromethyl ketone against ischemia-induced hippocampal neuronal damage.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 1998;18(8):819-23.
1998: Takuji Tanaka; Kunihiro Kawabata; M Kakumoto; Akira Hara; Akira Murakami; Wataru Kuki; Yoshito Takahashi; H Yonei; M Maeda; T Ota; S Odashima; T Yamane; Koichi Koshimizu; Hajime Ohigashi
Citrus auraptene exerts dose-dependent chemopreventive activity in rat large bowel tumorigenesis: the inhibition correlates with suppression of cell proliferation and lipid peroxidation and with induction of phase II drug-metabolizing enzymes.
Cancer research 1998;58(12):2550-6.
1998: Masayuki Niwa; Akira Hara; T Iwai; M Nakashima; H Yano; N Yoshimi; Hideki Mori; Toshihiko Uematsu
Relationship between magnitude of hypothermia during ischemia and preventive effect against post-ischemic DNA fragmentation in the gerbil hippocampus.
Brain research 1998;794(2):338-42.
1998: K Matsunaga; Naoki Yoshimi; Yasuhiro Yamada; Masahito Shimizu; Kunihiro Kawabata; Y Ozawa; Akira Hara; Hideki Mori
Inhibitory effects of nabumetone, a cyclooxygenase-2 inhibitor, and esculetin, a lipoxygenase inhibitor, on N-methyl-N-nitrosourea-induced mammary carcinogenesis in rats.
Japanese journal of cancer research : Gann 1998;89(5):496-501.
1998: Takuji Tanaka; Kunihiro Kawabata; M Kakumoto; K Matsunaga; Hideki Mori; Akira Murakami; Wataru Kuki; Yoshito Takahashi; H Yonei; K Satoh; Akira Hara; M Maeda; T Ota; S Odashima; Koichi Koshimizu; Hajime Ohigashi
Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by citrus auraptene in rats.
Carcinogenesis 1998;19(3):425-31.
1998: Akira Hara; Naoki Yoshimi; Hideki Mori
Evidence for apoptosis in human intracranial aneurysms.
Neurological research 1998;20(2):127-30.
1998: Masumi Suzui; Naoki Yoshimi; Akira Hara; Y Morishita; Takuji Tanaka; Hideki Mori
Genetic alterations in a patient with Turcot's syndrome.
Pathology international 1998;48(2):126-33.
1998: Yoshinobu Hirose; Shigeyuki Sugie; Naoki Yoshimi; K Matsunaga; Akira Hara; Hideki Mori
Induction of apoptosis in colonic epithelium treated with 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) and its modulation by a P4501A2 inducer, beta-naphthoflavone, in male F344 rats.
Cancer letters 1998;123(2):167-72.
1997: Masayuki Niwa; Akira Hara; T Iwai; T Sassa; Hideki Mori; Toshihiko Uematsu
Expression of Bax and Bcl-2 protein in the gerbil hippocampus following transient forebrain ischemia and its modification by phencyclidine.
Neurological research 1997;19(6):629-33.
1997: Akira Hara; Y Hirose; Naoki Yoshimi; T Tanaka; Hideki Mori
Expression of Bax and bcl-2 proteins, regulators of programmed cell death, in human brain tumors.
Neurological research 1997;19(6):623-8.
1997: Naoki Yoshimi; Kunihiro Kawabata; Akira Hara; K Matsunaga; Yasuhiro Yamada; Hideki Mori
Inhibitory effect of NS-398, a selective cyclooxygenase-2 inhibitor, on azoxymethane-induced aberrant crypt foci in colon carcinogenesis of F344 rats.
Japanese journal of cancer research : Gann 1997;88(11):1044-51.
1997: Takuji Tanaka; Kunihiro Kawabata; M Kakumoto; Hiroki Makita; Akira Hara; Hideki Mori; K Satoh; A Hara; Akira Murakami; Wataru Kuki; Yoshito Takahashi; H Yonei; Koichi Koshimizu; Hajime Ohigashi
Citrus auraptene inhibits chemically induced colonic aberrant crypt foci in male F344 rats.
Carcinogenesis 1997;18(11):2155-61.
1997: Takuji Tanaka; Kunihiro Kawabata; M Kakumoto; Hiroki Makita; K Matsunaga; Hideki Mori; K Satoh; Akira Hara; Akira Murakami; Koichi Koshimizu; Hajime Ohigashi
Chemoprevention of azoxymethane-induced rat colon carcinogenesis by a xanthine oxidase inhibitor, 1'-acetoxychavicol acetate.
Japanese journal of cancer research : Gann 1997;88(9):821-30.
1997: Akira Hara; Naoki Yoshimi; M Niwa; N Ino; Hideki Mori
Apoptosis induced by NS-398, a selective cyclooxygenase-2 inhibitor, in human colorectal cancer cell lines.
Japanese journal of cancer research : Gann 1997;88(6):600-4.
1997: Takuji Tanaka; Hiroki Makita; Toshihiko Kawamori; Kunihiro Kawabata; Hideki Mori; Akira Murakami; K Satoh; Akira Hara; Hajime Ohigashi; Koichi Koshimizu
A xanthine oxidase inhibitor 1'-acetoxychavicol acetate inhibits azoxymethane-induced colonic aberrant crypt foci in rats.
Carcinogenesis 1997;18(5):1113-8.
1997: Takuji Tanaka; Hiroki Makita; Kunihiro Kawabata; Hideki Mori; M Kakumoto; K Satoh; Akira Hara; T Sumida; T Tanaka; H Ogawa
Chemoprevention of azoxymethane-induced rat colon carcinogenesis by the naturally occurring flavonoids, diosmin and hesperidin.
Carcinogenesis 1997;18(5):957-65.
1997: Takuji Tanaka; Hiroki Makita; Kunihiro Kawabata; Hideki Mori; M Kakumoto; K Satoh; Akira Hara; T Sumida; K Fukutani; T Tanaka; H Ogawa
Modulation of N-methyl-N-amylnitrosamine-induced rat oesophageal tumourigenesis by dietary feeding of diosmin and hesperidin, both alone and in combination.
Carcinogenesis 1997;18(4):761-9.
1997: Takuji Tanaka; Hiroki Makita; M Ohnishi; Hideki Mori; K Satoh; Akira Hara; T Sumida; K Fukutani; T Tanaka; H Ogawa
Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis in rats by flavonoids diosmin and hesperidin, each alone and in combination.
Cancer research 1997;57(2):246-52.
1997: Masayuki Niwa; Akira Hara; Yutaka Kanamori; K Kohno; N Yoshimi; Hideki Mori; Toshihiko Uematsu
Comparison of susceptibility to apoptosis induced by rhTNF-alpha and cycloheximide between human circulating and exudated neutrophils.
Life sciences 1997;61(2):205-15.
1996: Hiroki Makita; Takuji Tanaka; H Fujitsuka; Norichika Tatematsu; K Satoh; Akira Hara; Hideki Mori
Chemoprevention of 4-nitroquinoline 1-oxide-induced rat oral carcinogenesis by the dietary flavonoids chalcone, 2-hydroxychalcone, and quercetin.
Cancer research 1996;56(21):4904-9.
1996: Akira Hara; Noboru Sakai; H Yamada; T Iwata
Clinoidal meningioma arising from falciforme process of optic canal: case report and review.
Neurological research 1996;18(3):237-40.
1996: Yoshinobu Hirose; N Yoshimi; Hiroki Makita; Akira Hara; Takuji Tanaka; Hideki Mori
Early alterations of apoptosis and cell proliferation in azoxymethane-initiated rat colonic epithelium.
Japanese journal of cancer research : Gann 1996;87(6):575-82.
1996: Yoshinobu Hirose; Takuji Tanaka; Hiroki Makita; M Yang; K Satoh; Akira Hara; M Maeda; H B Toriyama; Hideki Mori; H Tsuda
Suppressing effects of 6-(2,5-dichlorophenyl)-2,4-diamino-1,3,5-triazine and related synthetic compounds on azoxymethane-induced aberrant crypt foci in rat colon.
Japanese journal of cancer research : Gann 1996;87(6):549-54.
1996: N Yoshimi; N Ino; Masumi Suzui; Akira Hara; K Nakatani; S Sato; Hideki Mori
Telomerase activity of normal tissues and neoplasms in rat colon carcinogenesis induced by methylazoxymethanol acetate and its difference from that of human colonic tissues.
Molecular carcinogenesis 1996;16(1):1-5.
1996: M Ohnishi; Takuji Tanaka; Hiroki Makita; Toshihiko Kawamori; Hideki Mori; K Satoh; Akira Hara; Akira Murakami; Hajime Ohigashi; Koichi Koshimizu
Chemopreventive effect of a xanthine oxidase inhibitor, 1'-acetoxychavicol acetate, on rat oral carcinogenesis.
Japanese journal of cancer research : Gann 1996;87(4):349-56.
1996: Akira Hara; T Iwai; Masayuki Niwa; Toshihiko Uematsu; N Yoshimi; Takuji Tanaka; Hideki Mori
Immunohistochemical detection of Bax and Bcl-2 proteins in gerbil hippocampus following transient forebrain ischemia.
Brain research 1996;711(1-2):249-53.
1995: Akira Hara; N Yoshimi; Hideki Mori; T Iwai; Noboru Sakai; H Yamada; Masayuki Niwa
Hypothermic prevention of nuclear DNA fragmentation in gerbil hippocampus following transient forebrain ischemia.
Neurological research 1995;17(6):461-4.
1995: Takuji Tanaka; Toshihiko Kawamori; M Ohnishi; Hiroki Makita; Hideki Mori; K Satoh; Akira Hara
Suppression of azoxymethane-induced rat colon carcinogenesis by dietary administration of naturally occurring xanthophylls astaxanthin and canthaxanthin during the postinitiation phase.
Carcinogenesis 1995;16(12):2957-63.
1995: Akira Hara; N Yoshimi; Yoshinobu Hirose; N Ino; Takuji Tanaka; Hideki Mori
DNA fragmentation in granular cells of human cerebellum following global ischemia.
Brain research 1995;697(1-2):247-50.
1995: Yoshinobu Hirose; Takuji Tanaka; Toshihiko Kawamori; M Ohnishi; Hiroki Makita; Hideki Mori; K Satoh; Akira Hara
Chemoprevention of urinary bladder carcinogenesis by the natural phenolic compound protocatechuic acid in rats.
Carcinogenesis 1995;16(10):2337-42.
1995: Takuji Tanaka; Hiroki Makita; M Ohnishi; Hideki Mori; K Satoh; Akira Hara
Chemoprevention of rat oral carcinogenesis by naturally occurring xanthophylls, astaxanthin and canthaxanthin.
Cancer research 1995;55(18):4059-64.
1995: Toshihiko Kawamori; Takuji Tanaka; M Ohnishi; Yoshinobu Hirose; Y Nakamura; K Satoh; Akira Hara; Hideki Mori
Chemoprevention of azoxymethane-induced colon carcinogenesis by dietary feeding of S-methyl methane thiosulfonate in male F344 rats.
Cancer research 1995;55(18):4053-8.
1995: Hiroki Makita; Takuji Tanaka; M Ohnishi; Y Tamai; M Torihara; J Yamahara; Hideki Mori; K Satoh; Akira Hara
Inhibition of 4-nitroquinoline-1-oxide-induced rat oral carcinogenesis by dietary exposure of a new retinoidal butenolide, KYN-54, during the initiation and post-initiation phases.
Carcinogenesis 1995;16(9):2171-6.
1995: Takuji Tanaka; Hiroki Makita; M Ohnishi; Hideki Mori; K Satoh; Akira Hara
Inhibition of oral carcinogenesis by the arotinoid mofarotene (Ro 40-8757) in male F344 rats.
Carcinogenesis 1995;16(8):1903-7.
1995: Toshihiko Kawamori; Takuji Tanaka; Yoshinobu Hirose; K Satoh; Akira Hara; M Torihara; Y Tamai; J Yamahara; Hideki Mori
Suppression of azoxymethane-induced colonic aberrant crypt foci by dietary exposure to a novel synthesized retinoidal butenolide, 5-hydroxy-4-(2-phenyl-(E)ethenyl)-2(5H)-furanone, in rats.
Cancer letters 1995;92(2):159-65.
1995: Toshihiko Kawamori; Takuji Tanaka; Akira Hara; J Yamahara; Hideki Mori
Modifying effects of naturally occurring products on the development of colonic aberrant crypt foci induced by azoxymethane in F344 rats.
Cancer research 1995;55(6):1277-82.
1995: T Iwai; Akira Hara; Masayuki Niwa; M Nozaki; Toshihiko Uematsu; Noboru Sakai; H Yamada
Temporal profile of nuclear DNA fragmentation in situ in gerbil hippocampus following transient forebrain ischemia.
Brain research 1995;671(2):305-8.
1995: Akira Hara; Y Nishimura; Noboru Sakai; H Yamada; S Yanagawa
Effectiveness of intraoperative radiation therapy for recurrent supratentorial low grade glioma.
Journal of neuro-oncology 1995;25(3):239-43.
1994: Akira Hara; Y Kaku; Y Nishimura; Noboru Sakai; H Yamada
Remission of recurrent primary intracranial malignant lymphoma after high-dose intra-arterial corticosteroid administration and intra-arterial chemotherapy--case report.
Neurologia medico-chirurgica 1994;34(10):700-3.
1994: Takuji Tanaka; Hiroki Makita; M Ohnishi; Yoshinobu Hirose; A Wang; Hideki Mori; K Satoh; Akira Hara; H Ogawa
Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary curcumin and hesperidin: comparison with the protective effect of beta-carotene.
Cancer research 1994;54(17):4653-9.
1994: Akira Hara; W Zhang; H Kobayashi; S Niikawa; Noboru Sakai; H Yamada
A single cell gel electrophoresis technique for the detection of DNA damage induced by ACNU, an alkylating agent or irradiation in murine glioma cell lines.
Neurological research 1994;16(4):234-40.
1994: Takuji Tanaka; Toshihiko Kawamori; M Ohnishi; K Okamoto; Hideki Mori; Akira Hara
Chemoprevention of 4-nitroquinoline 1-oxide-induced oral carcinogenesis by dietary protocatechuic acid during initiation and postinitiation phases.
Cancer research 1994;54(9):2359-65.
1994: K Matsuura; Yasuo Bunai; Isao Ohya; Akira Hara; M Nakanishi; H Sawada
Ultrastructural localization of carbonyl reductase in mouse lung.
The Histochemical journal 1994;26(4):311-6.
1993: T Kojima; Takuji Tanaka; Toshihiko Kawamori; Akira Hara; Hideki Mori
Chemopreventive effects of dietary D,L-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor, on initiation and postinitiation stages of diethylnitrosamine-induced rat hepatocarcinogenesis.
Cancer research 1993;53(17):3903-7.
1993: Akira Hara; S Niikawa; W Zhang; Noboru Sakai; H Yamada; N Yoshimi; Hideki Mori
Identification of placental form of glutathione S-transferase in ACNU-resistant murine glioma cell lines.
Journal of neuro-oncology 1993;17(3):205-13.
1993: S Niikawa; Noboru Sakai; H Yamada; W Zhang; Akira Hara; K Shimokawa
Histochemistry with Helix pomatia agglutinin in human germ cell tumors: detection of nongerminomatous components and correlation between HPA reactivity and radiosensitivity in germinomas.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 1993;9(5):266-70; discussion 271.
1993: Akira Hara; Noboru Sakai; H Yamada; S Niikawa; N Yoshimi; Hideki Mori
Localization of the placental form of glutathione S-transferase messenger ribonucleic acid in human glioma cell lines.
Neurosurgery 1993;33(1):100-4; discussion 104-5.
1993: Akira Hara; Noboru Sakai; H Yamada; S Niikawa; N Yoshimi; H Mori; K Shimokawa
Expression of the placental form of glutathione S-transferase in pediatric gliomas.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 1993;9(3):142-6.
1993: S Niikawa; Akira Hara; S Shirakami; W Zhang; Noboru Sakai; H Yamada; K Shimokawa
Relationship between Ricinus communis agglutinin-1 binding and nucleolar organizer regions in human gliomas.
Neurologia medico-chirurgica 1993;33(6):345-9.
1993: Akira Hara; Y Araki; J Shinoda; H Hirayama; S Niikawa; Noboru Sakai; H Yamada
Central neurocytoma: proliferative assessment by nucleolar organizer region staining.
Surgical neurology 1993;39(5):343-7.
1993: W Zhang; Akira Hara; T Murakawa; S Niikawa; T Andoh; Noboru Sakai; H Yamada
Effect of interferon-gamma on ACNU-induced DNA damage and cytotoxicity in human glioblastoma cells.
Neurologia medico-chirurgica 1993;33(5):275-9.
1993: H Hirayama; Akira Hara; S Niikawa; T Iwai; Y Nishimura; T Ando; Noboru Sakai; H Yamada; M Takada
[Nucleolar organizer regions in meningiomas with reference to histopathological findings and recurrence].
Nō to shinkei = Brain and nerve 1993;45(4):355-61.
1993: W Zhang; Akira Hara; Noboru Sakai; T Andoh; H Yamada; Yoshinori Nozawa
Radiosensitization and inhibition of deoxyribonucleic acid repair in rat glioma cells by long-term treatment with 12-O-tetradecanoylphorbol 13-acetate.
Neurosurgery 1993;32(3):432-7; discussion 437.
1993: Takuji Tanaka; T Kojima; Akira Hara; H Sawada; Hideki Mori
Chemoprevention of oral carcinogenesis by DL-alpha-difluoromethylornithine, an ornithine decarboxylase inhibitor: dose-dependent reduction in 4-nitroquinoline 1-oxide-induced tongue neoplasms in rats.
Cancer research 1993;53(4):772-6.
1993: Akira Hara; Noboru Sakai; H Yamada; N Yoshimi; Takuji Tanaka; Hideki Mori
Immunoblot analysis of the placental form of glutathione S-transferase in protein extracted from paraffin-embedded human glioma tissue.
Journal of cancer research and clinical oncology 1993;119(8):493-6.
1992: S Niikawa; Akira Hara; W Zhang; Noboru Sakai; H Yamada; K Shimokawa
Proliferative assessment of craniopharyngioma and epidermoid by nucleolar organizer region staining.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 1992;8(8):453-6.
1992: S Niikawa; Akira Hara; T Ando; Noboru Sakai; H Yamada; K Shimokawa
Lectin cytochemistry combined with silver colloid staining of argyrophilic nucleolar organizer regions in human gliomas.
Neurologia medico-chirurgica 1992;32(9):653-8.
1992: S Niikawa; Akira Hara; T Ando; Noboru Sakai; H Yamada; K Shimokawa
Dolichos biflorus agglutinin binding to intracranial germ-cell tumors: detection of embryonal components in germinomas.
Acta neuropathologica 1992;83(4):347-51.
1992: S Niikawa; H Yamada; Noboru Sakai; T Ando; W Zhang; Akira Hara; K Shimokawa
Distribution of cellular carbohydrate moieties in human dysontogenetic brain tumors, especially in craniopharyngioma and epidermoid/dermoid.
Acta neuropathologica 1992;85(1):71-8.
1991: Akira Hara; S Niikawa; H Hirayama; Noboru Sakai; H Yamada; T Ohno; Takuji Tanaka; Hideki Mori
Correlation between nucleolar organizer region score and bromodeoxyuridine labeling index in C6 glioma cell line.
Journal of neuro-oncology 1991;11(2):149-55.
1991: Akira Hara; Noboru Sakai; H Yamada; S Niikawa; T Ohno; Takuji Tanaka; Hideki Mori
Proliferative assessment of GFAP-positive and GFAP-negative glioma cells by nucleolar organizer region staining.
Surgical neurology 1991;36(3):190-4.
1991: Akira Hara; Noboru Sakai; H Yamada; H Hirayama; Takuji Tanaka; Hideki Mori
Nucleolar organizer regions in vascular and neoplastic cells of human gliomas.
Neurosurgery 1991;29(2):211-5.
1991: Hideki Mori; Shigeyuki Sugie; A Okumura; Akira Hara; T Kinouchi; K Kataoka; Y Ohnishi
Genotoxicity of pyrene oxide and 1-nitropyrene oxides in hepatocyte primary culture/DNA repair test.
Mutation research 1991;262(4):233-8.
1991: Akira Hara; Noboru Sakai; H Yamada; Takuji Tanaka; Hideki Mori
Assessment of proliferative potential in gliomatosis cerebri.
Journal of neurology 1991;238(2):80-2.
1991: Akira Hara; Noboru Sakai; H Yamada; N Yoshimi; Takuji Tanaka; Hideki Mori
Rapid detection of proliferating potential in human brain tumors by nucleolar organizer region staining on squash preparations.
Journal of cancer research and clinical oncology 1991;117(6):510-4.
1991: Akira Hara; H Hirayama; Noboru Sakai; H Yamada; Takuji Tanaka; Hideki Mori
Nucleolar organizer region score and Ki-67 labelling index in high-grade gliomas and metastatic brain tumours.
Acta neurochirurgica 1991;109(1-2):37-41.
1990: KV Takenaka; Y Kanaho; Akira Hara; W Zhang; T Ando; Noboru Sakai; H Yamada; Yoshinori Nozawa
A guanine nucleotide-binding protein in human astrocytoma.
Neurological research 1990;12(4):223-5.
1990: Takuji Tanaka; Yoshio Mori; Y Morishita; Akira Hara; T Ohno; T Kojima; Hideki Mori
Inhibitory effect of sinigrin and indole-3-carbinol on diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats.
Carcinogenesis 1990;11(8):1403-6.
1990: H Iwata; N Yoshimi; Y Mori; Akira Hara; Hideki Mori
Genotoxicity of heterocyclic amines in the hepatocyte/DNA repair assay using hepatocytes of rats or mice pretreated with 3-methylcholanthrene.
Mutation research 1990;244(1):1-6.
1990: Hideki Mori; N Yoshimi; H Iwata; Yoshio Mori; Akira Hara; Takuji Tanaka; K Kawai
Carcinogenicity of naturally occurring 1-hydroxyanthraquinone in rats: induction of large bowel, liver and stomach neoplasms.
Carcinogenesis 1990;11(5):799-802.
1990: Akira Hara; H Hirayama; Noboru Sakai; H Yamada; Takuji Tanaka; Hideki Mori
Correlation between nucleolar organizer region staining and Ki-67 immunostaining in human gliomas.
Surgical neurology 1990;33(5):320-4.
1989: Takuji Tanaka; A Nishikawa; H Iwata; Yoshio Mori; Akira Hara; I Hirono; Hideki Mori
Enhancing effect of ethanol on aflatoxin B1-induced hepatocarcinogenesis in male ACI/N rats.
Japanese journal of cancer research : Gann 1989;80(6):526-30.
1989: Akira Hara; Noboru Sakai; H Yamada; Takuji Tanaka; K Kato; Hideki Mori; K Sato
Induction of glutathione S-transferase, placental type in T9 glioma cells by dibutyryladenosine 3',5'-cyclic monophosphate and modification of its expression by naturally occurring isothiocyanates.
Acta neuropathologica 1989;79(2):144-8.