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Michishige Harada

Research Profile

Anatomy

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Chemicals & Drugs

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Asthma

Genes & Molecular Sequences

Single Nucleotide Polymorphism

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Kelan G Tantisira; Qing Ling Duan; Michishige Harada; Blanca E Himes; Tomomitsu Hirota; Barbara J Klanderman; Christoph Lange; Jessica Lasky-Su; Ross Lazarus; Stephen C Lazarus; Robert F Lemanske; John J Lima; Augusto A Litonjua; Fernando D Martinez; David Mauger; Amy Murphy; Yusuke Nakamura; Stephen P Peters; Weiliang Qiu; Christine Sorkness; Jody Sylvia; Stanley Szefler; Mayumi Tamari; Scott T Weiss
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
Akira Isada; Satoshi Konno; Nobuyuki Hizawa; Mayumi Tamari; Tomomitsu Hirota; Michishige Harada; Yukiko Maeda; Takeshi Hattori; Ayumu Takahashi; Masaharu Nishimura
A functional polymorphism (-603A --> G) in the tissue factor gene promoter is associated with adult-onset asthma.
Masafumi Sakashita; Tomomitsu Hirota; Michishige Harada; Reiichiro Nakamichi; Tatsuhiko Tsunoda; Yoko Osawa; Akihiro Kojima; Masayuki Okamoto; Dai Suzuki; Seita Kubo; Yoshimasa Imoto; Yusuke Nakamura; Mayumi Tamari; Shigeharu Fujieda
Prevalence of allergic rhinitis and sensitization to common aeroallergens in a Japanese population.

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All Publications

2011: Kelan G Tantisira; Qing Ling Duan; Michishige Harada; Blanca E Himes; Tomomitsu Hirota; Barbara J Klanderman; Christoph Lange; Jessica Lasky-Su; Ross Lazarus; Stephen C Lazarus; Robert F Lemanske; John J Lima; Augusto A Litonjua; Fernando D Martinez; David Mauger; Amy Murphy; Yusuke Nakamura; Stephen P Peters; Weiliang Qiu; Christine Sorkness; Jody Sylvia; Stanley Szefler; Mayumi Tamari; Scott T Weiss
Genomewide association between GLCCI1 and response to glucocorticoid therapy in asthma.
The New England journal of medicine 2011;365(13):1173-83.
2010: Akira Isada; Satoshi Konno; Nobuyuki Hizawa; Mayumi Tamari; Tomomitsu Hirota; Michishige Harada; Yukiko Maeda; Takeshi Hattori; Ayumu Takahashi; Masaharu Nishimura
A functional polymorphism (-603A --> G) in the tissue factor gene promoter is associated with adult-onset asthma.
Journal of human genetics 2010;55(3):167-74.
2010: Masafumi Sakashita; Tomomitsu Hirota; Michishige Harada; Reiichiro Nakamichi; Tatsuhiko Tsunoda; Yoko Osawa; Akihiro Kojima; Masayuki Okamoto; Dai Suzuki; Seita Kubo; Yoshimasa Imoto; Yusuke Nakamura; Mayumi Tamari; Shigeharu Fujieda
Prevalence of allergic rhinitis and sensitization to common aeroallergens in a Japanese population.
International archives of allergy and immunology 2010;151(3):255-61.
2009: Michishige Harada; Kazuhiko Obara; Tomomitsu Hirota; Tomohiro Yoshimoto; Yuki Hitomi; Masafumi Sakashita; Satoru Doi; Akihiko Miyatake; Kimie Fujita; Tadao Enomoto; Masami Taniguchi; Noritaka Higashi; Yuma Fukutomi; Kenji Nakanishi; Yusuke Nakamura; Mayumi Tamari
A functional polymorphism in IL-18 is associated with severity of bronchial asthma.
American journal of respiratory and critical care medicine 2009;180(11):1048-55.
2009: Yuki Hitomi; Motohiro Ebisawa; Morimitsu Tomikawa; Takanori Imai; Takatsugu Komata; Tomomitsu Hirota; Michishige Harada; Masafumi Sakashita; Yoichi Suzuki; Naoki Shimojo; Yoichi Kohno; Kimie Fujita; Akihiko Miyatake; Satoru Doi; Tadao Enomoto; Masami Taniguchi; Noritaka Higashi; Yusuke Nakamura; Mayumi Tamari
Associations of functional NLRP3 polymorphisms with susceptibility to food-induced anaphylaxis and aspirin-induced asthma.
The Journal of allergy and clinical immunology 2009;124(4):779-85.e6.
2009: Mayumi Tamari; Michishige Harada; Tomomitsu Hirota; Yuki Hitomi
[Bronchial asthma and genes of the innate immunity].
Arerugī = [Allergy] 2009;58(7):766-71.
2009: Michishige Harada; Tomomitsu Hirota; Aya I Jodo; Satoru Doi; Makoto Kameda; Kimie Fujita; Akihiko Miyatake; Tadao Enomoto; Emiko Noguchi; Shigemi Yoshihara; Motohiro Ebisawa; Hirohisa Saito; Kenji Matsumoto; Yusuke Nakamura; Steven F Ziegler; Mayumi Tamari
Functional analysis of the thymic stromal lymphopoietin variants in human bronchial epithelial cells.
American journal of respiratory cell and molecular biology 2009;40(3):368-74.
2009: Mayumi Tamari; Michishige Harada; Tomomitsu Hirota; Yusuke Nakamura
Host molecular defense mechanisms against Chlamydophila pneumoniae and genetic studies of immune-response-related genes in asthma.
Recent patents on inflammation & allergy drug discovery 2009;3(1):17-25.
2008: Tomomitsu Hirota; Michishige Harada; Masafumi Sakashita; Satoru Doi; Akihiko Miyatake; Kimie Fujita; Tadao Enomoto; Motohiro Ebisawa; Shigemi Yoshihara; Emiko Noguchi; Hirohisa Saito; Yusuke Nakamura; Mayumi Tamari
Genetic polymorphism regulating ORM1-like 3 (Saccharomyces cerevisiae) expression is associated with childhood atopic asthma in a Japanese population.
The Journal of allergy and clinical immunology 2008;121(3):769-70.
2007: Xiaofeng Jiang; Satoshi Kojo; Michishige Harada; Nobuhiro Ohkohchi; Masaru Taniguchi; Ken-ichiro Seino
Mechanism of NKT cell-mediated transplant tolerance.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(6):1482-90.
2007: Michishige Harada; Kazuko Nakashima; Tomomitsu Hirota; Makiko Shimizu; Satoru Doi; Kimie Fujita; Taro Shirakawa; Tadao Enomoto; Mamoru Yoshikawa; Hiroshi Moriyama; Kenji Matsumoto; Hirohisa Saito; Yoichi Suzuki; Yusuke Nakamura; Mayumi Tamari
Functional polymorphism in the suppressor of cytokine signaling 1 gene associated with adult asthma.
American journal of respiratory cell and molecular biology 2007;36(4):491-6.
2006: Michishige Harada; Kumiko Magara-Koyanagi; Hiroshi Watarai; Yuko Nagata; Yasuyuki Ishii; Satoshi Kojo; Shigetoshi Horiguchi; Yoshitaka Okamoto; Toshinori Nakayama; Nobutaka Suzuki; Wen-Chen Yeh; Shizuo Akira; Hiroshi Kitamura; Osamu Ohara; Ken-ichiro Seino; Masaru Taniguchi
IL-21-induced Bepsilon cell apoptosis mediated by natural killer T cells suppresses IgE responses.
The Journal of experimental medicine 2006;203(13):2929-37.
2006: Xiaofeng Jiang; Miwa Morita; Atsushi Sugioka; Michishige Harada; Satoshi Kojo; Hiroshi Wakao; Hiroshi Watarai; Nobuhiro Ohkohchi; Masaru Taniguchi; Ken-ichiro Seino
The importance of CD25+ CD4+ regulatory T cells in mouse hepatic allograft tolerance.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society 2006;12(7):1112-8.
2006: Yuya Kunisaki; Yoshihiko Tanaka; Terukazu Sanui; Ayumi Inayoshi; Mayuko Noda; Toshinori Nakayama; Michishige Harada; Masaru Taniguchi; Takehiko Sasazuki; Yoshinori Fukui
DOCK2 is required in T cell precursors for development of Valpha14 NK T cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(8):4640-5.
2005: Satoshi Kojo; Ken-ichiro Seino; Michishige Harada; Hiroshi Watarai; Hiroshi Wakao; Tetsuro Uchida; Toshinori Nakayama; Masaru Taniguchi
Induction of regulatory properties in dendritic cells by Valpha14 NKT cells.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):3648-55.
2005: Xiaofeng Jiang; Takeshi Shimaoka; Satoshi Kojo; Michishige Harada; Hiroshi Watarai; Hiroshi Wakao; Nobuhiro Ohkohchi; Shin Yonehara; Masaru Taniguchi; Ken-ichiro Seino
Cutting edge: critical role of CXCL16/CXCR6 in NKT cell trafficking in allograft tolerance.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(4):2051-5.
2005: Ken-ichiro Seino; Shin-Ichiro Fujii; Michishige Harada; Shinichiro Motohashi; Toshinori Nakayama; Takehiko Fujisawa; Masaru Taniguchi
Valpha14 NKT cell-mediated anti-tumor responses and their clinical application.
Springer seminars in immunopathology 2005;27(1):65-74.
2004: Ken-ichiro Seino; Michishige Harada; Masaru Taniguchi
NKT cells are relatively resistant to apoptosis.
Trends in immunology 2004;25(5):219-21.
2004: Michishige Harada; Ken-ichiro Seino; Hiroshi Wakao; Sakura Sakata; Yuko Ishizuka; Toshihiro Ito; Satoshi Kojo; Toshinori Nakayama; Masaru Taniguchi
Down-regulation of the invariant Valpha14 antigen receptor in NKT cells upon activation.
International immunology 2004;16(2):241-7.
2004: Seiichiro Kobayashi; Yoshikatsu Kaneko; Ken-ichiro Seino; Yoshihito Yamada; Shinichiro Motohashi; Junzo Koike; Kaoru Sugaya; Takayuki Kuriyama; Shigetaka Asano; Tomiyasu Tsuda; Hiroshi Wakao; Michishige Harada; Satoshi Kojo; Toshinori Nakayama; Masaru Taniguchi
Impaired IFN-gamma production of Valpha24 NKT cells in non-remitting sarcoidosis.
International immunology 2004;16(2):215-22.
2003: Michishige Harada; Masaru Taniguchi
[A specific ligand of V alpha 14 NKT cells and its presentation].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2003;48(8 Suppl):1126-32.
2003: Eisuke Kondo; Hiroshi Wakao; Haruhiko Koseki; Toshitada Takemori; Satoshi Kojo; Michishige Harada; Minako Takahashi; Sakura Sakata; Chiori Shimizu; Toshihiro Ito; Toshinori Nakayama; Masaru Taniguchi
Expression of recombination-activating gene in mature peripheral T cells in Peyer's patch.
International immunology 2003;15(3):393-402.
2003: Masaru Taniguchi; Michishige Harada; Satoshi Kojo; Toshinori Nakayama; Hiroshi Wakao
The regulatory role of Valpha14 NKT cells in innate and acquired immune response.
Annual review of immunology 2003;21():483-513.
2002: Michishige Harada; Masaru Taniguchi
[The regulatory role of V alpha 14 NKT cells in innate and acquired immune response].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2002;47(16 Suppl):2109-16.
2002: Yasunori Akutsu; Toshinori Nakayama; Michishige Harada; Tetsu Kawano; Shinichiro Motohashi; Eiko Shimizu; Toshihiro Ito; Noriaki Kamada; Takeshi Saito; Hisahiro Matsubara; Yukimasa Miyazawa; Takenori Ochiai; Masaru Taniguchi
Expansion of lung V alpha 14 NKT cells by administration of alpha-galactosylceramide-pulsed dendritic cells.
Japanese journal of cancer research : Gann 2002;93(4):397-403.
2001: Noriaki Kamada; H Iijima; K Kimura; Michishige Harada; Eiko Shimizu; Tetsu Kawano; Hiroshi Shinkai; Toshinori Nakayama; T Sakai; L Brossay; M Kronenberg; Masaru Taniguchi
Crucial amino acid residues of mouse CD1d for glycolipid ligand presentation to V(alpha)14 NKT cells.
International immunology 2001;13(7):853-61.
2001: M Yamasaki; Takahisa Sasho; Hideshige Moriya; M Kanno; Michishige Harada; N Kamada; E Shimizu; Toshinori Nakayama; Masaru Taniguchi
Extrathymic development of V alpha 11 T cells in placenta during pregnancy and their possible physiological role.
Journal of immunology (Baltimore, Md. : 1950) 2001;166(12):7244-9.
2001: Tae Kwang Shin; Toshinori Nakayama; Yasunori Akutsu; Shinichiro Motohashi; Y Shibata; Michishige Harada; Noriaki Kamada; C Shimizu; Eiko Shimizu; Takeshi Saito; Takenori Ochiai; Masaru Taniguchi
Inhibition of tumor metastasis by adoptive transfer of IL-12-activated Valpha14 NKT cells.
International journal of cancer. Journal international du cancer 2001;91(4):523-8.
2000: K Ito; M Karasawa; Tetsu Kawano; T Akasaka; Haruhiko Koseki; Yasunori Akutsu; E Kondo; S Sekiya; K Sekikawa; Michishige Harada; Masakatsu Yamashita; Toshinori Nakayama; Masaru Taniguchi
Involvement of decidual Valpha14 NKT cells in abortion.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(2):740-4.
2000: Y Kaneko; Michishige Harada; T Kawano; Masakatsu Yamashita; Y Shibata; F Gejyo; Toshinori Nakayama; Masaru Taniguchi
Augmentation of Valpha14 NKT cell-mediated cytotoxicity by interleukin 4 in an autocrine mechanism resulting in the development of concanavalin A-induced hepatitis.
The Journal of experimental medicine 2000;191(1):105-14.
1998: Tetsu Kawano; J Cui; Yasuhiko Koezuka; I Toura; Yoshikatsu Kaneko; Hiroshi Sato; E Kondo; Michishige Harada; Haruhiko Koseki; Toshinori Nakayama; Yoshikazu Tanaka; Masaru Taniguchi
Natural killer-like nonspecific tumor cell lysis mediated by specific ligand-activated Valpha14 NKT cells.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5690-3.