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Philip Harbach

Research Profile

Chemicals & Drugs

Procedures

Mutagenicity Tests

Anatomy

Living Beings

Physiology

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Publications

TOP 3
Dorothea K Torous; Nikki E Hall; Anne H Illi-Love; Marilyn S Diehl; Karin Cederbrant; Kerstin Sandelin; Ingrid Pontén; George Bolcsfoldi; Lynnette Ferguson; Amira Pearson; Jenness B Majeska; James P Tarca; Geoffrey M Hynes; Anthony Lynch; James P McNamee; Pascale V Bellier; Monique Parenteau; David Blakey; Janet Bayley; Bas-Jan M van der Leede; Philippe Vanparys; Philip R Harbach; Shuou Zhao; Anthony L Filipunas; Carol W Johnson; Carol R Tometsko; Stephen D Dertinger
Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood.
DM Zimmer; Philip R Harbach; William Mattes; CS Aaron
Comparison of mutant frequencies at the transgenic lambda LacI and cII/cI loci in control and ENU-treated Big Blue mice.
Philip R Harbach; DM Zimmer; Anthony L Filipunas; William Mattes; CS Aaron
Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice.

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All Publications

2005: Dorothea K Torous; Nikki E Hall; Anne H Illi-Love; Marilyn S Diehl; Karin Cederbrant; Kerstin Sandelin; Ingrid Pontén; George Bolcsfoldi; Lynnette Ferguson; Amira Pearson; Jenness B Majeska; James P Tarca; Geoffrey M Hynes; Anthony Lynch; James P McNamee; Pascale V Bellier; Monique Parenteau; David Blakey; Janet Bayley; Bas-Jan M van der Leede; Philippe Vanparys; Philip R Harbach; Shuou Zhao; Anthony L Filipunas; Carol W Johnson; Carol R Tometsko; Stephen D Dertinger
Interlaboratory validation of a CD71-based flow cytometric method (Microflow) for the scoring of micronucleated reticulocytes in mouse peripheral blood.
Environmental and molecular mutagenesis 2005;45(1):44-55.
1999: DM Zimmer; Philip R Harbach; William Mattes; CS Aaron
Comparison of mutant frequencies at the transgenic lambda LacI and cII/cI loci in control and ENU-treated Big Blue mice.
Environmental and molecular mutagenesis 1999;33(3):249-56.
1999: Philip R Harbach; DM Zimmer; Anthony L Filipunas; William Mattes; CS Aaron
Spontaneous mutation spectrum at the lambda cII locus in liver, lung, and spleen tissue of Big Blue transgenic mice.
Environmental and molecular mutagenesis 1999;33(2):132-43.
1999: DM Zimmer; Philip R Harbach; S S Mattano; R L Yu; William Mattes; CS Aaron
Lack of response to multiple genotoxic agents at the hprt locus in peripheral blood T-lymphocytes of cynomolgus monkeys.
Environmental and molecular mutagenesis 1999;33(2):123-31.
1999: Philip R Harbach; S S Mattano; DM Zimmer; Anthony L Filipunas; Y Wang; CS Aaron
DNA sequence analysis of hprt mutants persisting in peripheral blood of cynomolgus monkeys more than two years after ENU treatment.
Environmental and molecular mutagenesis 1999;33(1):42-8.
1998: DM Zimmer; Philip R Harbach; William Mattes; CS Aaron
Effect of plating medium and phage storage on mutant frequency and titer in the lambda cII transgenic mutation assay.
Environmental and molecular mutagenesis 1998;32(4):325-30.
1997: Z Zhao; KA Koeplinger; GE Padbury; CS Aaron; Philip R Harbach; J K Mayo; William Mattes; GL Bundy
Contribution of serum protein association to discrepancy between the in vivo and in vitro UDS results for 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843).
Mutation research 1997;395(2-3):119-26.
1996: Z Zhao; K A Koeplinger; GE Padbury; MJ Hauer; G L Bundy; L S Banitt; T M Schwartz; DAVID ZIMMERMANN; Philip R Harbach; J K Mayo; CS Aaron
Bioactivation of 6,7-dimethyl-2,4-di-1-pyrrolidinyl-7H-pyrrolo[2,3-d]pyrimidine (U-89843) to reactive intermediates that bind covalently to macromolecules and produce genotoxicity.
Chemical research in toxicology 1996;9(8):1230-9.
1996: CS Aaron; DM Zimmer; Philip R Harbach; R L Yu
End points for biomonitoring: assay sensitivity/selectivity.
Environmental health perspectives 1996;104 Suppl 3():521-5.
1996: DM Zimmer; X B Zhang; Philip R Harbach; J K Mayo; CS Aaron
Spontaneous and ethylnitrosourea-induced mutation fixation and molecular spectra at the lacI transgene in the Big Blue rat-2 embryo cell line.
Environmental and molecular mutagenesis 1996;28(4):325-33.
1995: CS Aaron; R L Yu; Philip R Harbach; J M Mazurek; D H Swenson; D Kirkland; R Marshall; S McEnaney
Comparative mutagenicity testing of ceftiofur sodium: I. Positive results in in vitro cytogenetics.
Mutation research 1995;345(1-2):27-35.
1995: Philip R Harbach; S S Mattano; DM Zimmer; Y Wang; CS Aaron
DNA sequence analysis of spontaneous hprt mutations arising in vivo in cynomolgus monkey T-lymphocytes.
Environmental and molecular mutagenesis 1995;26(3):218-25.
1995: S S Mattano; DM Zimmer; Philip R Harbach; T C Hunter; CS Aaron
Southern blot analysis of T-cell receptor gene rearrangements in cynomolgus monkeys, and identification of a progenitor cell HPRT mutation.
Environmental and molecular mutagenesis 1995;26(2):119-26.
1993: CS Aaron; Philip R Harbach; S S Mattano; J K Mayo; Y Wang; R L Yu; DM Zimmer
Risk and benefit evaluation in development of pharmaceutical products.
Environmental health perspectives 1993;101 Suppl 3():291-5.
1992: Philip R Harbach; A L Filipunas; Y Wang; CS Aaron
DNA sequence analysis of spontaneous and N-ethyl-N-nitrosourea-induced hprt mutations arising in vivo in cynomolgus monkey T-lymphocytes.
Environmental and molecular mutagenesis 1992;20(2):96-105.
1991: Philip R Harbach; S K Wiser; A L Smith; C R Grzegorczyk; CS Aaron
Strain differences in in vitro rat hepatocyte unscheduled DNA synthesis (UDS): effect of UV is independent of strain while increased sensitivity is apparent using Fischer-344 instead of Sprague-Dawley rats.
Mutation research 1991;252(2):149-55.
1991: Philip R Harbach; H J Rostami; CS Aaron; S K Wiser; C R Grzegorczyk
Evaluation of four methods for scoring cytoplasmic grains in the in vitro unscheduled DNA synthesis (UDS) assay.
Mutation research 1991;252(2):139-48.
1989: CS Aaron; Philip R Harbach; S K Wiser; C R Grzegorczyk; A L Smith
The in vitro unscheduled DNA synthesis (UDS) assay in rat primary hepatocytes: evaluation of 2-furoic acid and 7 drug candidates.
Mutation research 1989;223(2):163-9.
1989: CS Aaron; Philip R Harbach; K L Steinmetz; J P Bakke; Jon C Mirsalis
The in vitro unscheduled DNA synthesis (UDS) assay in rat primary hepatocytes: evaluation of 24 drug candidates.
Mutation research 1989;223(2):141-51.
1989: CS Aaron; L F Stankowski; Philip R Harbach; R Valencia; J K Mayo; Jon C Mirsalis; J H Mazurek; K L Steinmetz; S K Wiser; DM Zimmer
Comparative mutagenicity testing of a drug candidate, U-48753E: mechanism of induction of gene mutations in mammalian cells and quantitation of potential hazard.
Mutation research 1989;223(2):111-20.
1989: Philip R Harbach; CS Aaron; S K Wiser; C R Grzegorczyk; A L Smith
The in vitro unscheduled DNA synthesis (UDS) assay in rat primary hepatocytes. Validation of improved methods for primary culture including data on the lack of effect of ionizing radiation.
Mutation research 1989;216(2):101-10.
1988: Philip R Harbach; DM Zimmer; J H Mazurek; B K Bhuyan
Mutagenicity of the antitumor antibiotic CC-1065 and its analogues in mammalian (V79) cells and bacteria.
Cancer research 1988;48(1):32-6.
1986: Philip R Harbach; R J Trzos; J H Mazurek; DM Zimmer; GL Petzold; B K Bhuyan
Genotoxicity of the antitumor antibiotic CC-1065.
Mutagenesis 1986;1(6):407-10.
1986: D H Swenson; GL Petzold; Philip R Harbach
The binding of 1-(2-hydroxyethyl)-1-nitrosourea to DNA in vitro and to DNA of thymus and marrow in C57BL mice in vivo.
Cancer letters 1986;33(1):75-81.
1983: B K Bhuyan; DM Zimmer; J H Mazurek; R J Trzos; Philip R Harbach; V S Shu; M A Johnson
Comparative genotoxicity of adriamycin and menogarol, two anthracycline antitumor agents.
Cancer research 1983;43(11):5293-7.
1980: D H Swenson; Philip R Harbach; R J Trzos
The relationship between alkylation of specific DNA bases and induction of sister chromatid exchange.
Carcinogenesis 1980;1(11):931-6.