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Jochen Harbott

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Cai Chen; Martin Dugas; Ute Fischer; Sebastian Ginzel; Michael Gombert; Jochen Harbott; Jianda Hu; Vera Okpanyi; Silja Röttgers; Andrea Teigler-Schlegel; Ralf Thiele; Christoph Bartenhagen; Vera Binder; Jutta Bradtke; Arndt Borkhardt
Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia.
Petra Dörge; Jochen Harbott; Rolf Koehler; Wolf-Dieter Ludwig; Barbara Meissner; Anja Möricke; Richard Ratei; Denis Schewe; Martin Schrappe; André Schrauder; Martin Stanulla; Andrea Teigler-Schlegel; Martin Zimmermann; Claus R Bartram; Jean-Pierre Bouquin; Gunnar Cario
IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.
Ursula Creutzig; Eveline S J M de Bont; Michael Dworzak; Brenda Gibson; Jochen Harbott; Henrik Hasle; Donna Johnston; G J L Kaspers; Akitoshi Kinoshita; Thomas Lehrnbecher; Guy Leverger; Ester Mejstrikova; Soheil Meshinchi; Andrea Pession; Susana C Raimondi; Dirk Reinhardt; Jan Stary; Lillian Sung; Marry M van den Heuvel-Eibrink; Christian M Zwaan; Souichi Adachi
Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel.

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All Publications

2013: Cai Chen; Martin Dugas; Ute Fischer; Sebastian Ginzel; Michael Gombert; Jochen Harbott; Jianda Hu; Vera Okpanyi; Silja Röttgers; Andrea Teigler-Schlegel; Ralf Thiele; Christoph Bartenhagen; Vera Binder; Jutta Bradtke; Arndt Borkhardt
Next-generation-sequencing-based risk stratification and identification of new genes involved in structural and sequence variations in near haploid lymphoblastic leukemia.
Genes, chromosomes & cancer 2013;52(6):564-79.
2013: Petra Dörge; Jochen Harbott; Rolf Koehler; Wolf-Dieter Ludwig; Barbara Meissner; Anja Möricke; Richard Ratei; Denis Schewe; Martin Schrappe; André Schrauder; Martin Stanulla; Andrea Teigler-Schlegel; Martin Zimmermann; Claus R Bartram; Jean-Pierre Bouquin; Gunnar Cario
IKZF1 deletion is an independent predictor of outcome in pediatric acute lymphoblastic leukemia treated according to the ALL-BFM 2000 protocol.
Haematologica 2013;98(3):428-32.
2012: Ursula Creutzig; Eveline S J M de Bont; Michael Dworzak; Brenda Gibson; Jochen Harbott; Henrik Hasle; Donna Johnston; G J L Kaspers; Akitoshi Kinoshita; Thomas Lehrnbecher; Guy Leverger; Ester Mejstrikova; Soheil Meshinchi; Andrea Pession; Susana C Raimondi; Dirk Reinhardt; Jan Stary; Lillian Sung; Marry M van den Heuvel-Eibrink; Christian M Zwaan; Souichi Adachi
Diagnosis and management of acute myeloid leukemia in children and adolescents: recommendations from an international expert panel.
Blood 2012;120(16):3187-205.
2012: Martin Schrappe; Lewis B Silverman; Anne Birgitta Versluys; André Baruchel; Bruce M Camitta; Valentino Conter; Meenakshi Devidas; Gabriele Escherich; Paul S Gaynon; Jochen Harbott; Mats Heyman; Keizo Horibe; Stephen P Hunger; Georg Mann; Akira Ohara; Jacques Otten; Ching-Hon Pui; Sue Richards; Hansjörg Riehm; Vaskar Saha; Martin Zimmermann
Outcomes after induction failure in childhood acute lymphoblastic leukemia.
The New England journal of medicine 2012;366(15):1371-81.
2011: Brian Balgobind; Andre Baruchel; Berna Beverloo; Jean-Michel Cayuela; Jacqueline Cloos; Ursula Creutzig; Valerie de Haas; Jochen Harbott; Iris H I M Hollink; G J L Kaspers; Rob Pieters; Dirk Reinhardt; Jan Stary; Anne R M von Bergh; Zuzana Zemanova; Martin Zimmermann; Christian M Zwaan; Susan T C J M Arentsen-Peters; Marry M van den Heuvel-Eibrink
Integrative analysis of type-I and type-II aberrations underscores the genetic heterogeneity of pediatric acute myeloid leukemia.
Haematologica 2011;96(10):1478-87.
2011: P M Kakadia; G Mellert; H Quentmeier; S Röttgers; Karsten Spiekermann; B Tizazu; Jochen Harbott; Stefan K Bohlander
A novel ABL1 fusion to the SH2 containing inositol phosphatase-1 (SHIP1) in acute lymphoblastic leukemia (ALL).
Leukemia 2011;25(10):1645-9.
2011: Lilian Kuster; Reinhard Grausenburger; Gerhard Fuka; Ulrike Kaindl; Gerd Krapf; Andrea Inthal; Georg Mann; Maximilian Kauer; Johannes Rainer; Reinhard Kofler; Andrew Hall; Markus Metzler; Lüder Hinrich Meyer; Claus Meyer; Jochen Harbott; Rolf Marschalek; Sabine Strehl; Oskar A Haas; Renate Panzer-Grümayer
ETV6/RUNX1-positive relapses evolve from an ancestral clone and frequently acquire deletions of genes implicated in glucocorticoid signaling.
Blood 2011;117(9):2658-67.
2011: Erica Ballabio; Andrea Biondi; Jacqueline Boultwood; Jutta Bradtke; Joanna M Bridger; Giovanni Cazzaniga; Elisa Garimberti; Giovanni Giudici; Jochen Harbott; Samantha J L Knight; Regina Regan; Andrea Teigler-Schlegel; James S Wainscoat; Sabrina Tosi
Genomic imbalances are confined to non-proliferating cells in paediatric patients with acute myeloid leukaemia and a normal or incomplete karyotype.
PloS one 2011;6(6):e20607.
2010: Gudrun Göhring; Kyra Michalova; Berna Beverloo; David Betts; Jochen Harbott; Oskar A Haas; Gitte Kerndrup; Laura Sainati; Eva Bergstraesser; Henrik Hasle; Jan Stary; Monika Trebo; Marry M van den Heuvel-Eibrink; Marco Zecca; Elisabeth R van Wering; Alexandra Fischer; Peter Noellke; Brigitte Strahm; Franco Locatelli; Charlotte M Niemeyer; Brigitte Schlegelberger
Complex karyotype newly defined: the strongest prognostic factor in advanced childhood myelodysplastic syndrome.
Blood 2010;116(19):3766-9.
2010: Christine J Harrison; Oskar Haas; Jochen Harbott; Andrea Biondi; Martin Stanulla; Jan Trka; Shai Izraeli
Detection of prognostically relevant genetic abnormalities in childhood B-cell precursor acute lymphoblastic leukaemia: recommendations from the Biology and Diagnosis Committee of the International Berlin-Frankfürt-Münster study group.
British journal of haematology 2010;151(2):132-42.
2010: S Wildenhain; C Ruckert; S Röttgers; Jochen Harbott; Wolf-Dieter Ludwig; F R Schuster; K Beldjord; V Binder; R Slany; J Hauer; Arndt Borkhardt
Expression of cell-cell interacting genes distinguishes HLXB9/TEL from MLL-positive childhood acute myeloid leukemia.
Leukemia 2010;24(9):1657-60.
2010: Gunnar Cario; Martin Zimmermann; Renja Romey; Stefan Gesk; Inga Vater; Jochen Harbott; André Schrauder; Anja Moericke; Shai Izraeli; Takashi Akasaka; Martin J S Dyer; Reiner Siebert; Martin Schrappe; Martin Stanulla
Presence of the P2RY8-CRLF2 rearrangement is associated with a poor prognosis in non-high-risk precursor B-cell acute lymphoblastic leukemia in children treated according to the ALL-BFM 2000 protocol.
Blood 2010;115(26):5393-7.
2010: Silja Röttgers; M Gombert; Andrea Teigler-Schlegel; Kerstin Busch; Ulrike Gamerdinger; Robert K Slany; Jochen Harbott; Arndt Borkhardt
ALK fusion genes in children with atypical myeloproliferative leukemia.
Leukemia 2010;24(6):1197-200.
2010: Herbert Pichler; Anja Möricke; Georg Mann; Andrea Teigler-Schlegel; Felix Niggli; Karin Nebral; Margit König; Andrea Inthal; Daniela Krehan; Michael Dworzak; Dasa Janousek; Jochen Harbott; Martin Schrappe; Helmut Gadner; Sabine Strehl; Oskar A Haas; Renate Panzer-Grümayer; Andishe Attarbaschi
Prognostic relevance of dic(9;20)(p11;q13) in childhood B-cell precursor acute lymphoblastic leukaemia treated with Berlin-Frankfurt-Münster (BFM) protocols containing an intensive induction and post-induction consolidation therapy.
British journal of haematology 2010;149(1):93-100.
2010: Anja Möricke; Martin Zimmermann; Alfred Reiter; Günter Henze; André Schrauder; Helmut Gadner; Wolf-Dieter Ludwig; J Ritter; Jochen Harbott; Georg Mann; Thomas Klingebiel; Felix Zintl; C Niemeyer; Bernhard Kremens; Felix Niggli; Dietrich Niethammer; Karl Welte; Martin Stanulla; E Odenwald; Hansjörg Riehm; Martin Schrappe
Long-term results of five consecutive trials in childhood acute lymphoblastic leukemia performed by the ALL-BFM study group from 1981 to 2000.
Leukemia 2010;24(2):265-84.
2009: H von Goessel; U Jacobs; S Semper; M Krumbholz; Thorsten Langer; T Keller; A Schrauder; V H J van der Velden; J J M van Dongen; Jochen Harbott; E R Panzer-Grümayer; M Schrappe; Wolfgang Rascher; Markus Metzler
Cluster analysis of genomic ETV6-RUNX1 (TEL-AML1) fusion sites in childhood acute lymphoblastic leukemia.
Leukemia research 2009;33(8):1082-8.
2009: Norihiko Kawamata; Seishi Ogawa; Karl Seeger; Renate Kirschner-Schwabe; Thien Huynh; John Chen; Nairi Megrabian; Jochen Harbott; Martin Zimmermann; Günter Henze; Martin Schrappe; Claus R Bartram; H Phillip Koeffler
Molecular allelokaryotyping of relapsed pediatric acute lymphoblastic leukemia.
International journal of oncology 2009;34(6):1603-12.
2009: Ronald Adler; Susanne Viehmann; Eberhard Kuhlisch; Yvonne Martiniak; Silja Röttgers; Jochen Harbott; Meinolf Suttorp
Correlation of BCR/ABL transcript variants with patients' characteristics in childhood chronic myeloid leukaemia.
European journal of haematology 2009;82(2):112-8.
2008: Norihiko Kawamata; Seishi Ogawa; Martin Zimmermann; Birte Niebuhr; Carol Stocking; Masashi Sanada; Kari Hemminki; Go Yamatomo; Yasuhito Nannya; Rolf Koehler; Thomas Flohr; Carl W Miller; Jochen Harbott; Wolf-Dieter Ludwig; Martin Stanulla; Martin Schrappe; Claus R Bartram; H Phillip Koeffler
Cloning of genes involved in chromosomal translocations by high-resolution single nucleotide polymorphism genomic microarray.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11921-6.
2008: Christoph le Viseur; Marc Hotfilder; Simon Bomken; Kerrie Wilson; Silja Röttgers; André Schrauder; Annegret Rosemann; Julie Irving; Ronald W Stam; Leonard D Shultz; Jochen Harbott; Heribert Jürgens; Martin Schrappe; Rob Pieters; Josef Vormoor
In childhood acute lymphoblastic leukemia, blasts at different stages of immunophenotypic maturation have stem cell properties.
Cancer cell 2008;14(1):47-58.
2008: Andishe Attarbaschi; Georg Mann; Renate Panzer-Grümayer; Silja Röttgers; Manuel Steiner; Margit König; Eva Csinady; Michael Dworzak; Markus Seidel; Dasa Janousek; Anja Möricke; Carsten Reichelt; Jochen Harbott; Martin Schrappe; Helmut Gadner; Oskar A Haas
Minimal residual disease values discriminate between low and high relapse risk in children with B-cell precursor acute lymphoblastic leukemia and an intrachromosomal amplification of chromosome 21: the Austrian and German acute lymphoblastic leukemia Berlin-Frankfurt-Munster (ALL-BFM) trials.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2008;26(18):3046-50.
2008: Doris Steinemann; Gunnar Cario; Martin Stanulla; Leonid Karawajew; Marcel Tauscher; Anja Weigmann; Gudrun Göhring; Wolf-Dieter Ludwig; Jochen Harbott; Bernhard Radlwimmer; Claus Bartram; Peter Lichter; Martin Schrappe; Brigitte Schlegelberger
Copy number alterations in childhood acute lymphoblastic leukemia and their association with minimal residual disease.
Genes, chromosomes & cancer 2008;47(6):471-80.
2008: Anja Möricke; Alfred Reiter; Martin Zimmermann; Helmut Gadner; Martin Stanulla; Michael Dördelmann; Lutz Löning; Rita Beier; Wolf-Dieter Ludwig; Richard Ratei; Jochen Harbott; Joachim Boos; Georg Mann; Felix Niggli; Andreas Feldges; Günter Henze; Karl Welte; Jörn D Beck; Thomas Klingebiel; Charlotte Niemeyer; Felix Zintl; Udo Bode; Christian Urban; Helmut Wehinger; Dietrich Niethammer; Hansjörg Riehm; Martin Schrappe
Risk-adjusted therapy of acute lymphoblastic leukemia can decrease treatment burden and improve survival: treatment results of 2169 unselected pediatric and adolescent patients enrolled in the trial ALL-BFM 95.
Blood 2008;111(9):4477-89.
2008: Julia Hauer; Sabrina Tosi; Friedhelm R Schuster; Jochen Harbott; Hans-Jochem Kolb; Arndt Borkhardt
Graft versus leukemia effect after haploidentical HSCT in a MLL-negative infant AML with HLXB9/ETV6 rearrangement.
Pediatric blood & cancer 2008;50(4):921-3.
2008: Sabine Strehl; Karin Nebral; Margit König; Jochen Harbott; Herbert Strobl; Richard Ratei; Stephanie Struski; Bella Bielorai; michel lessard; Martin Zimmermann; Oskar A Haas; Shai Izraeli
ETV6-NCOA2: a novel fusion gene in acute leukemia associated with coexpression of T-lymphoid and myeloid markers and frequent NOTCH1 mutations.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(4):977-83.
2008: Jan Starý; Irith Baumann; Ursula Creutzig; Jochen Harbott; Kyra Michalova; Charlotte Niemeyer
Getting the numbers straight in pediatric MDS: distribution of subtypes after exclusion of down syndrome.
Pediatric blood & cancer 2008;50(2):435-6.
2008: Norihiko Kawamata; Seishi Ogawa; Martin Zimmermann; Motohiro Kato; Masashi Sanada; Kari Hemminki; Go Yamatomo; Yasuhito Nannya; Rolf Koehler; Thomas Flohr; Carl W Miller; Jochen Harbott; Wolf-Dieter Ludwig; Martin Stanulla; Martin Schrappe; Claus R Bartram; H Phillip Koeffler
Molecular allelokaryotyping of pediatric acute lymphoblastic leukemias by high-resolution single nucleotide polymorphism oligonucleotide genomic microarray.
Blood 2008;111(2):776-84.
2007: Anja Troeger; Sonja Gudowius; Gabriele Escherich; Monique L den Boer; Ludmila Glouchkova; Birgit Ackermann; Roland Meisel; Hans-Jürgen Laws; Marketa Groeger; Rüdiger Wessalowski; Reinhart Willers; Jochen Harbott; Rob Pieters; Ulrich Goebel; Gritta E Janka-Schaub; Helmut Hanenberg; Dagmar Dilloo
High nerve growth factor receptor (p75NTR) expression is a favourable prognostic factor in paediatric B cell precursor-acute lymphoblastic leukaemia.
British journal of haematology 2007;139(3):450-7.
2007: Kerstin Busch; T Keller; Uta Fuchs; R-F Yeh; Jochen Harbott; I Klose; J Wiemels; A Novosel; Alfred Reiter; Arndt Borkhardt
Identification of two distinct MYC breakpoint clusters and their association with various IGH breakpoint regions in the t(8;14) translocations in sporadic Burkitt-lymphoma.
Leukemia 2007;21(8):1739-51.
2007: Christine Damm-Welk; Kerstin Busch; Birgit Burkhardt; Jutta Schieferstein; Susanne Viehmann; Ilske Oschlies; Wolfram Klapper; Martin Zimmermann; Jochen Harbott; Alfred Reiter; Willi Woessmann
Prognostic significance of circulating tumor cells in bone marrow or peripheral blood as detected by qualitative and quantitative PCR in pediatric NPM-ALK-positive anaplastic large-cell lymphoma.
Blood 2007;110(2):670-7.
2007: Claudia Haferlach; Harald Rieder; Debra M Lillington; Nicole Dastugue; Anne Hagemeijer; Jochen Harbott; Stephan Stilgenbauer; Sakari Knuutila; Bertil Johansson; Christa Fonatsch
Proposals for standardized protocols for cytogenetic analyses of acute leukemias, chronic lymphocytic leukemia, chronic myeloid leukemia, chronic myeloproliferative disorders, and myelodysplastic syndromes.
Genes, chromosomes & cancer 2007;46(5):494-9.
2007: Markus Metzler; Jochen Bruch; Daniel Stachel; Thorsten Langer; Arndt Borkhardt; Jochen Harbott; Wolfgang Rascher; Wolfgang Holter
Temporary blast reduction after immunoglobulin administration for congenital cytomegalovirus infection masking infant leukemia with cryptic MLL rearrangement.
Leukemia research 2007;31(4):553-7.
2006: Sabine Strehl; Margit König; Claus Meyer; Björn Schneider; Jochen Harbott; Ulrich Jäger; Anne von Bergh; Ivan F Loncarevic; Marie Jarosova; Helmut H Schmidt; Steven D P Moore; Rolf Marschalek; Oskar A Haas
Molecular dissection of t(11;17) in acute myeloid leukemia reveals a variety of gene fusions with heterogeneous fusion transcripts and multiple splice variants.
Genes, chromosomes & cancer 2006;45(11):1041-9.
2006: Birgit Burkhardt; Jochen Bruch; Martin Zimmermann; K Strauch; Reza Parwaresch; Wolf-Dieter Ludwig; Lana Harder; Brigitte Schlegelberger; F Mueller; Jochen Harbott; Alfred Reiter
Loss of heterozygosity on chromosome 6q14-q24 is associated with poor outcome in children and adolescents with T-cell lymphoblastic lymphoma.
Leukemia 2006;20(8):1422-9.
2006: J Neudenberger; Marc Hotfilder; Annegret Rosemann; Claudia Langebrake; Dirk Reinhardt; Rob Pieters; André Schrauder; Martin Schrappe; Silja Röttgers; Jochen Harbott; Josef Vormoor
Lack of expression of the chondroitin sulphate proteoglycan neuron-glial antigen 2 on candidate stem cell populations in paediatric acute myeloid leukaemia/abn(11q23) and acute lymphoblastic leukaemia/t(4;11).
British journal of haematology 2006;133(3):337-44.
2006: Melchior Lauten; André Schrauder; Christian Kardinal; Jochen Harbott; Karl Welte; Brigitte Schlegelberger; Martin Schrappe; Nils von neuhoff
Unsupervised proteome analysis of human leukaemia cells identifies the Valosin-containing protein as a putative marker for glucocorticoid resistance.
Leukemia 2006;20(5):820-6.
2005: Anja Möricke; M Zimmermann; A Reiter; H Gadner; E Odenwald; Jochen Harbott; Wolf-Dieter Ludwig; Hansjörg Riehm; Martin Schrappe
Prognostic impact of age in children and adolescents with acute lymphoblastic leukemia: data from the trials ALL-BFM 86, 90, and 95.
Klinische Pädiatrie 2005;217(6):310-20.
2005: E Renate Panzer-Grümayer; Giovanni Cazzaniga; V H J van der Velden; Laura del Giudice; Martina Peham; Georg Mann; Cornelia Eckert; André Schrauder; Giuseppe Germano; Jochen Harbott; Giuseppe Basso; Andrea Biondi; Jacques J M van Dongen; Helmut Gadner; Oskar A Haas
Immunogenotype changes prevail in relapses of young children with TEL-AML1-positive acute lymphoblastic leukemia and derive mainly from clonal selection.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(21):7720-7.
2005: Sabrina Tosi; Erica Ballabio; Andrea Teigler-Schlegel; Jacqueline Boultwood; Jochen Bruch; Jochen Harbott
Characterization of 6q abnormalities in childhood acute myeloid leukemia and identification of a novel t(6;11)(q24.1;p15.5) resulting in a NUP98-C6orf80 fusion in a case of acute megakaryoblastic leukemia.
Genes, chromosomes & cancer 2005;44(3):225-32.
2005: Dirk Reinhardt; Sylke Diekamp; Claudia Langebrake; J Ritter; Jan Stary; Michael Dworzak; André Schrauder; Martin Zimmermann; Gudrun Fleischhack; W-D Ludwig; Jochen Harbott; Ursula Creutzig
Acute megakaryoblastic leukemia in children and adolescents, excluding Down's syndrome: improved outcome with intensified induction treatment.
Leukemia 2005;19(8):1495-6.
2005: Friedhelm Schuster; Monika Führer; Willi Woessmann; Alfred Reiter; Jochen Harbott; Susanne Viehmann; Arndt Borkhardt
Treatment of relapsed acute myelogeneous leukaemia with MLL/AF 6 fusion after stem cell transplantation by intensive reinduction followed by adoptive immunotherapy.
Leukemia 2005;19(7):1273-4; author reply 1275-6.
2005: Anthony V Moorman; Susana C Raimondi; Ching-Hon Pui; A Baruchel; A Biondi; Andrew J Carroll; E Forestier; Paul S Gaynon; Jochen Harbott; Dieter Harms; Nyla A Heerema; R Pieters; Martin Schrappe; Lewis B Silverman; E Vilmer; Christine J Harrison
No prognostic effect of additional chromosomal abnormalities in children with acute lymphoblastic leukemia and 11q23 abnormalities.
Leukemia 2005;19(4):557-63.
2005: Marc Hotfilder; Silja Röttgers; Annegret Rosemann; André Schrauder; Martin Schrappe; Rob Pieters; Heribert Jürgens; Jochen Harbott; Josef Vormoor
Leukemic stem cells in childhood high-risk ALL/t(9;22) and t(4;11) are present in primitive lymphoid-restricted CD34+CD19- cells.
Cancer research 2005;65(4):1442-9.
2004: Thorben Kracht; Martin Schrappe; Sabine Strehl; Alfred Reiter; Holger-Andreas Elsner; Jan Trka; Gunnar Cario; Susanne Viehmann; Jochen Harbott; Arndt Borkhardt; Markus Metzler; Thorsten Langer; Roland Repp; Rolf Marschalek; Karl Welte; Oskar A Haas; Martin Stanulla
NQO1 C609T polymorphism in distinct entities of pediatric hematologic neoplasms.
Haematologica 2004;89(12):1492-7.
2004: Henrik Hasle; I Baumann; Eva Bergsträsser; SUSANNA FENU; Alain Fischer; Gabriela Kardos; Gitte B Kerndrup; Franco Locatelli; Tim Rogge; Kirk R Schultz; Jan Starý; Monika M Trebo; Marry M van den Heuvel-Eibrink; Jochen Harbott; Peter Nöllke; Charlotte M Niemeyer
The International Prognostic Scoring System (IPSS) for childhood myelodysplastic syndrome (MDS) and juvenile myelomonocytic leukemia (JMML).
Leukemia 2004;18(12):2008-14.
2004: Barbara Meissner; Martin Stanulla; Wolf-Dieter Ludwig; Jochen Harbott; Anja Möricke; Karl Welte; Martin Schrappe
The GSTT1 deletion polymorphism is associated with initial response to glucocorticoids in childhood acute lymphoblastic leukemia.
Leukemia 2004;18(11):1920-3.
2004: Markus Metzler; Pamela L Strissel; Reiner Strick; Charlotte Niemeyer; Silja Roettgers; Arndt Borkhardt; Jochen Harbott; Wolf D Ludwig; Martin Stanulla; Martin Schrappe; Dirk Reinhardt; Ursula Creutzig; Jörn D Beck; Wolfgang Rascher; Roland Repp; Thorsten Langer
Emergence of translocation t(9;11)-positive leukemia during treatment of childhood acute lymphoblastic leukemia.
Genes, chromosomes & cancer 2004;41(3):291-6.
2004: Monika Wilda; Kerstin Busch; Irmgard Klose; Thomas Keller; Willi Woessmann; Joachim Kreuder; Jochen Harbott; Arndt Borkhardt
Level of MYC overexpression in pediatric Burkitt's lymphoma is strongly dependent on genomic breakpoint location within the MYC locus.
Genes, chromosomes & cancer 2004;41(2):178-82.
2004: Kerstin Busch; Arndt Borkhardt; Wilhelm Wössmann; Alfred Reiter; Jochen Harbott
Combined polymerase chain reaction methods to detect c-myc/IgH rearrangement in childhood Burkitt's lymphoma for minimal residual disease analysis.
Haematologica 2004;89(7):818-25.
2004: Ingo Tamm; Stephan Richter; Doreen Oltersdorf; Ursula Creutzig; Jochen Harbott; Frank Scholz; Leonid Karawajew; Wolf-Dieter Ludwig; Christian Wuchter
High expression levels of x-linked inhibitor of apoptosis protein and survivin correlate with poor overall survival in childhood de novo acute myeloid leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(11):3737-44.
2004: Nyla A Heerema; Jochen Harbott; S Galimberti; Bruce M Camitta; Paul S Gaynon; Gritta E Janka-Schaub; W Kamps; G Basso; Ching-Hon Pui; Martin Schrappe; M-F Auclerc; Andrew J Carroll; Valentino Conter; Christine J Harrison; Jeanette Pullen; Susana C Raimondi; S Richards; Hansjörg Riehm; Harland Sather; Jonathan J Shuster; Lewis B Silverman; M G Valsecchi; M Aricò
Secondary cytogenetic aberrations in childhood Philadelphia chromosome positive acute lymphoblastic leukemia are nonrandom and may be associated with outcome.
Leukemia 2004;18(4):693-702.
2004: NL Ramakers-van Woerden; Berna Beverloo; Anjo J P Veerman; B M Camitta; Anne H Loonen; Elisabeth R van Wering; Rosalyn M Slater; Jochen Harbott; Monique L den Boer; W D Ludwig; O A Haas; Gritta E Janka-Schaub; Rob Pieters
In vitro drug-resistance profile in infant acute lymphoblastic leukemia in relation to age, MLL rearrangements and immunophenotype.
Leukemia 2004;18(3):521-9.
2004: Martina Peham; Marianne Konrad; Jochen Harbott; Margit König; Oskar A Haas; E Renate Panzer-Grümayer
Clonal variation of the immunogenotype in relapsed ETV6/RUNX1-positive acute lymphoblastic leukemia indicates subclone formation during early stages of leukemia development.
Genes, chromosomes & cancer 2004;39(2):156-60.
2004: Bernard M Fine; Martin Stanulla; Martin Schrappe; Minh Ho; Susanne Viehmann; Jochen Harbott; Linda M Boxer
Gene expression patterns associated with recurrent chromosomal translocations in acute lymphoblastic leukemia.
Blood 2004;103(3):1043-9.
2004: Markus Metzler; U Brehm; Thorsten Langer; Susanne Viehmann; Arndt Borkhardt; Martin Stanulla; Martin Schrappe; Jochen Harbott; Jörn D Beck; Wolfgang Rascher; Roland Repp
Asymmetric multiplex-polymerase chain reaction - a high throughput method for detection and sequencing genomic fusion sites in t(4;11).
British journal of haematology 2004;124(1):47-54.
2003: Sabrina Tosi; Jim Hughes; Stephen W Scherer; Kazuhiko Nakabayashi; Jochen Harbott; Oskar A Haas; Giovanni Cazzaniga; Andrea Biondi; Helena Kempski; Lyndal Kearney
Heterogeneity of the 7q36 breakpoints in the t(7;12) involving ETV6 in infant leukemia.
Genes, chromosomes & cancer 2003;38(2):191-200.
2003: Christian M Zwaan; Soheil Meshinchi; Jerald P Radich; Anjo J P Veerman; Dieuwke R Huismans; Leonhard Munske; Martina Podleschny; Karel Hählen; Rob Pieters; Martin Zimmermann; Dirk Reinhardt; Jochen Harbott; Ursula Creutzig; G J L Kaspers; Frank Griesinger
FLT3 internal tandem duplication in 234 children with acute myeloid leukemia: prognostic significance and relation to cellular drug resistance.
Blood 2003;102(7):2387-94.
2003: Gabriela Kardos; Irith Baumann; S Jane Passmore; Franco Locatelli; Henrik Hasle; Kirk R Schultz; Jan Starý; Annette Schmitt-Graeff; Alexandra Fischer; Jochen Harbott; Judith M Chessells; Ian Hann; SUSANNA FENU; Angelo Cantú Rajnoldi; Gitte B Kerndrup; Elisabeth R van Wering; Tim Rogge; Peter Nollke; Charlotte M Niemeyer
Refractory anemia in childhood: a retrospective analysis of 67 patients with particular reference to monosomy 7.
Blood 2003;102(6):1997-2003.
2003: Susanne Viehmann; Andrea Teigler-Schlegel; Jochen Bruch; Claudia Langebrake; Dirk Reinhardt; Jochen Harbott
Monitoring of minimal residual disease (MRD) by real-time quantitative reverse transcription PCR (RQ-RT-PCR) in childhood acute myeloid leukemia with AML1/ETO rearrangement.
Leukemia 2003;17(6):1130-6.
2003: Jochen Bruch; Monika Wilda; Andrea Teigler-Schlegel; Jochen Harbott; Arndt Borkhardt; Markus Metzler
Occurrence of an MLL/LAF4 fusion gene caused by the insertion ins(11;2)(q23;q11.2q11.2) in an infant with acute lymphoblastic leukemia.
Genes, chromosomes & cancer 2003;37(1):106-9.
2003: Thorsten Langer; Markus Metzler; Dirk Reinhardt; Susanne Viehmann; Arndt Borkhardt; Martin Reichel; Martin Stanulla; Martin Schrappe; Ursula Creutzig; Jörg Ritter; Thomas Leis; Ulla Jacobs; Jochen Harbott; Jörn D Beck; Wolfgang Rascher; Roland Repp
Analysis of t(9;11) chromosomal breakpoint sequences in childhood acute leukemia: almost identical MLL breakpoints in therapy-related AML after treatment without etoposides.
Genes, chromosomes & cancer 2003;36(4):393-401.
2003: Ulrike Gamerdinger; Andrea Teigler-Schlegel; Sabine Pils; Jochen Bruch; Susanne Viehmann; Monika Keller; Anna Jauch; Jochen Harbott
Cryptic chromosomal aberrations leading to an AML1/ETO rearrangement are frequently caused by small insertions.
Genes, chromosomes & cancer 2003;36(3):261-72.
2002: Christian M Zwaan; G J L Kaspers; Rob Pieters; Karel Hählen; Dieuwke R Huismans; Martin Zimmermann; Jochen Harbott; Rosalyn M Slater; Ursula Creutzig; Anjo J P Veerman
Cellular drug resistance in childhood acute myeloid leukemia is related to chromosomal abnormalities.
Blood 2002;100(9):3352-60.
2002: Arndt Borkhardt; Christian Wuchter; Susanne Viehmann; Sabine Pils; Andrea Teigler-Schlegel; Martin Stanulla; M Zimmermann; Wolf-Dieter Ludwig; Gritta E Janka-Schaub; Martin Schrappe; Jochen Harbott
Infant acute lymphoblastic leukemia - combined cytogenetic, immunophenotypical and molecular analysis of 77 cases.
Leukemia 2002;16(9):1685-90.
2002: Marc Hotfilder; Silja Röttgers; Annegret Rosemann; Heribert Jürgens; Jochen Harbott; Josef Vormoor
Immature CD34+CD19- progenitor/stem cells in TEL/AML1-positive acute lymphoblastic leukemia are genetically and functionally normal.
Blood 2002;100(2):640-6.
2002: NL Ramakers-van Woerden; Rob Pieters; D Hoelzer; Rosalyn M Slater; Monique L den Boer; Anne H Loonen; Jochen Harbott; Gritta E Janka-Schaub; W-D Ludwig; Gert Ossenkoppele; Elisabeth R van Wering; Anjo J P Veerman
In vitro drug resistance profile of Philadelphia positive acute lymphoblastic leukemia is heterogeneous and related to age: a report of the Dutch and German Leukemia Study Groups.
Medical and pediatric oncology 2002;38(6):379-86.
2002: Jill Brown; mays jawad; Stephen R F Twigg; Kaan Saracoglu; Axel Sauerbrey; Angela E Thomas; Roland Eils; Jochen Harbott; Lyndal Kearney
A cryptic t(5;11)(q35;p15.5) in 2 children with acute myeloid leukemia with apparently normal karyotypes, identified by a multiplex fluorescence in situ hybridization telomere assay.
Blood 2002;99(7):2526-31.
2001: Arndt Borkhardt; Andrea Teigler-Schlegel; Uta Fuchs; C Keller; Margit König; Jochen Harbott; Oskar A Haas
An ins(X;11)(q24;q23) fuses the MLL and the Septin 6/KIAA0128 gene in an infant with AML-M2.
Genes, chromosomes & cancer 2001;32(1):82-8.
2001: Uta Fuchs; G Rehkamp; Oskar A Haas; Robert K Slany; M Kōnig; SE Bojesen; RM Bohle; Christine Damm-Welk; Wolf-Dieter Ludwig; Jochen Harbott; Arndt Borkhardt
The human formin-binding protein 17 (FBP17) interacts with sorting nexin, SNX2, and is an MLL-fusion partner in acute myelogeneous leukemia.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(15):8756-61.
2001: T Ferrari; B Weber; Sabine Pils; Jochen Harbott; Arndt Borkhardt
Absence of point mutations within the AML-1 gene in patients with MDS/AML and loss of chromosome 5q or 7.
Annals of hematology 2001;80(2):72-3.
2001: Karl Seeger; Susanne Viehmann; D Buchwald; Jochen Harbott; Martin Schrappe; Jan Stary; Günter Henze; Jan Trka
Treatment response and residual-disease monitoring in initial and relapsed TEL-AML1 positive childhood ALL.
Leukemia 2001;15(2):280-2.
2001: Christian Wuchter; Richard Ratei; G Spahn; Claudia Schoch; Jochen Harbott; Susanne Schnittger; Torsten Haferlach; U Creutzig; C Sperling; Leonid Karawajew; Wolf-Dieter Ludwig
Impact of CD133 (AC133) and CD90 expression analysis for acute leukemia immunophenotyping.
Haematologica 2001;86(2):154-61.
2001: I Scholz; Susanne Popp; Martin Granzow; Brigitte Schoell; Heidi Holtgreve-Grez; S Takeuchi; Martin Schrappe; Jochen Harbott; Andrea Teigler-Schlegel; M Zimmermann; Christine Fischer; H P Koeffler; Claus R Bartram; Anna Jauch
Comparative genomic hybridization in childhood acute lymphoblastic leukemia: correlation with interphase cytogenetics and loss of heterozygosity analysis.
Cancer genetics and cytogenetics 2001;124(2):89-97.
2000: Martin Schrappe; Alfred Reiter; Martin Zimmermann; Jochen Harbott; Wolf-Dieter Ludwig; Günter Henze; Helmut Gadner; E Odenwald; Hansjörg Riehm
Long-term results of four consecutive trials in childhood ALL performed by the ALL-BFM study group from 1981 to 1995. Berlin-Frankfurt-Münster.
Leukemia 2000;14(12):2205-22.
2000: Sabrina Tosi; Jochen Harbott; Andrea Teigler-Schlegel; Oskar A Haas; H Pirc-Danoewinata; Christine J Harrison; Andrea Biondi; Giovanni Cazzaniga; Helena Kempski; Stephen W Scherer; Lyndal Kearney
t(7;12)(q36;p13), a new recurrent translocation involving ETV6 in infant leukemia.
Genes, chromosomes & cancer 2000;29(4):325-32.
2000: NL Ramakers-van Woerden; Rob Pieters; Anne H Loonen; Isabelle Hubeek; Ellen van Drunen; Berna Beverloo; Rosalyn M Slater; Jochen Harbott; Jeanette Seyfarth; Elisabeth R van Wering; Karel Hählen; Kjeld Schmiegelow; Gritta E Janka-Schaub; Anjo J P Veerman
TEL/AML1 gene fusion is related to in vitro drug sensitivity for L-asparaginase in childhood acute lymphoblastic leukemia.
Blood 2000;96(3):1094-9.
2000: Arndt Borkhardt; SE Bojesen; Oskar A Haas; Uta Fuchs; D Bartelheimer; Ivan F Loncarevic; RM Bohle; Jochen Harbott; Roland Repp; U Jaeger; Susanne Viehmann; T Henn; P Korth; D Scharr; Fritz H Lampert
The human GRAF gene is fused to MLL in a unique t(5;11)(q31;q23) and both alleles are disrupted in three cases of myelodysplastic syndrome/acute myeloid leukemia with a deletion 5q.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(16):9168-73.
2000: Christian Wuchter; Leonid Karawajew; Velia Ruppert; Martin Schrappe; Jochen Harbott; Richard Ratei; Bernd Dörken; Wolf-Dieter Ludwig
Constitutive expression levels of CD95 and Bcl-2 as well as CD95 function and spontaneous apoptosis in vitro do not predict the response to induction chemotherapy and relapse rate in childhood acute lymphoblastic leukaemia.
British journal of haematology 2000;110(1):154-60.
2000: Christian Wuchter; Jochen Harbott; Claudia Schoch; Susanne Schnittger; Arndt Borkhardt; Leonid Karawajew; Richard Ratei; Velia Ruppert; Torsten Haferlach; U Creutzig; Bernd Dörken; Wolf-Dieter Ludwig
Detection of acute leukemia cells with mixed lineage leukemia (MLL) gene rearrangements by flow cytometry using monoclonal antibody 7.1.
Leukemia 2000;14(7):1232-8.
2000: Christian Wuchter; K Leonid; Velia Ruppert; Martin Schrappe; Thomas Büchner; Claudia Schoch; Torsten Haferlach; Jochen Harbott; Richard Ratei; Bernd Dörken; Wolf-Dieter Ludwig
Clinical significance of P-glycoprotein expression and function for response to induction chemotherapy, relapse rate and overall survival in acute leukemia.
Haematologica 2000;85(7):711-21.
2000: Martin Schrappe; Alfred Reiter; Wolf-Dieter Ludwig; Jochen Harbott; Martin Zimmermann; Wolfgang Hiddemann; Charlotte Niemeyer; Günter Henze; A Feldges; Felix Zintl; Bernhard Kornhuber; Jörg Ritter; Karl Welte; Helmut Gadner; Hansjörg Riehm
Improved outcome in childhood acute lymphoblastic leukemia despite reduced use of anthracyclines and cranial radiotherapy: results of trial ALL-BFM 90. German-Austrian-Swiss ALL-BFM Study Group.
Blood 2000;95(11):3310-22.
2000: Martin Stanulla; Brigitte Kasper; Martin Schrappe; Susanne Viehmann; Jochen Harbott; Wolf-Dieter Ludwig; Karl Welte
Granulocyte colony-stimulating factor receptor expression and 11q23/MLL genotype in childhood acute lymphoblastic leukemia developing during the first 18 months of life.
Leukemia 2000;14(2):337-8.
2000: J Bernstein; Nicole Dastugue; Oskar A Haas; Jochen Harbott; N A Heerema; J L Huret; Judith Landman-Parker; M M LeBeau; C Leonard; G Mann; Marie-Pierre Pages; Christine Perot; H Pirc-Danoewinata; B Roitzheim; C M Rubin; M Slociak; F Viguie
Nineteen cases of the t(1;22)(p13;q13) acute megakaryblastic leukaemia of infants/children and a review of 39 cases: report from a t(1;22) study group.
Leukemia 2000;14(1):216-8.
1999: E Gillert; Thomas Leis; Roland Repp; Martin Reichel; A Hösch; I Breitenlohner; Sabine Angermüller; Arndt Borkhardt; Jochen Harbott; Fritz H Lampert; F Griesinger; Johann Greil; Georg H Fey; Rolf Marschalek
A DNA damage repair mechanism is involved in the origin of chromosomal translocations t(4;11) in primary leukemic cells.
Oncogene 1999;18(33):4663-71.
1999: Rina J Jaju; Oskar A Haas; Michael J Neat; Jochen Harbott; Vaskar Saha; Jacqueline Boultwood; J M Brown; H Pirc-Danoewinata; B W Krings; U Müller; Stephan W Morris; james wainscoat; Lyndal Kearney
A new recurrent translocation, t(5;11)(q35;p15.5), associated with del(5q) in childhood acute myeloid leukemia. The UK Cancer Cytogenetics Group (UKCCG)
Blood 1999;94(2):773-80.
1999: Susanne Viehmann; Arndt Borkhardt; Fritz H Lampert; Jochen Harbott
Multiplex PCR--a rapid screening method for detection of gene rearrangements in childhood acute lymphoblastic leukemia.
Annals of hematology 1999;78(4):157-62.
1999: Ivan F Loncarevic; B Roitzheim; J Ritterbach; Susanne Viehmann; Arndt Borkhardt; Fritz H Lampert; Jochen Harbott
Trisomy 21 is a recurrent secondary aberration in childhood acute lymphoblastic leukemia with TEL/AML1 gene fusion.
Genes, chromosomes & cancer 1999;24(3):272-7.
1999: Henrik Hasle; Maurizio Aricò; Giuseppe Basso; Andrea Biondi; A Cantù-Rajnoldi; Ursula Creutzig; SUSANNA FENU; C Fonatsch; O A Haas; Jochen Harbott; Gabriela Kardos; Gitte B Kerndrup; G Mann; Charlotte M Niemeyer; H Ptoszkova; Jörg Ritter; R Slater; Jan Starý; B Stollmann-Gibbels; A M Testi; Elisabeth R van Wering; Martin Zimmermann
Myelodysplastic syndrome, juvenile myelomonocytic leukemia, and acute myeloid leukemia associated with complete or partial monosomy 7. European Working Group on MDS in Childhood (EWOG-MDS).
Leukemia 1999;13(3):376-85.
1998: Martin Schrappe; M Aricò; Jochen Harbott; A Biondi; Martin Zimmermann; Valentino Conter; Alfred Reiter; M G Valsecchi; Helmut Gadner; G Basso; Claus R Bartram; Fritz H Lampert; Hansjörg Riehm; G Masera
Philadelphia chromosome-positive (Ph+) childhood acute lymphoblastic leukemia: good initial steroid response allows early prediction of a favorable treatment outcome.
Blood 1998;92(8):2730-41.
1998: Richard Ratei; C Sperling; Leonid Karawajew; G Schott; Martin Schrappe; Jochen Harbott; Hansjörg Riehm; Wolf-Dieter Ludwig
Immunophenotype and clinical characteristics of CD45-negative and CD45-positive childhood acute lymphoblastic leukemia.
Annals of hematology 1998;77(3):107-14.
1998: Monika Führer; Stefan Burdach; Wolfram Ebell; Helmut Gadner; R Haas; Jochen Harbott; Gritta E Janka-Schaub; Thomas Klingebiel; Bernhard Kremens; Charlotte Niemeyer; Udo Rampf; Alfred Reiter; Jörg Ritter; A Schulz; U Walther; Cornelia Zeidler; Christine Bender-Götze
Relapse and clonal disease in children with aplastic anemia (AA) after immunosuppressive therapy (IST): the SAA 94 experience. German/Austrian Pediatric Aplastic Anemia Working Group.
Klinische Pädiatrie 1998;210(4):173-9.
1998: Thomas Leis; Roland Repp; Arndt Borkhardt; Markus Metzler; F Schläger; Jochen Harbott; Fritz H Lampert
A new fingerprint method for sequence analysis of chromosomal translocations at the genomic DNA level.
Leukemia 1998;12(5):758-63.
1998: Michael Dördelmann; Martin Schrappe; Alfred Reiter; Martin Zimmermann; Norbert Graf; G Schott; Fritz H Lampert; Jochen Harbott; Charlotte Niemeyer; J Ritter; Wolfgang Dörffel; G Nessler; Joachim Kühl; Hansjörg Riehm
Down's syndrome in childhood acute lymphoblastic leukemia: clinical characteristics and treatment outcome in four consecutive BFM trials. Berlin-Frankfurt-Münster Group.
Leukemia 1998;12(5):645-51.
1998: J Ritterbach; W Hiddemann; J D Beck; Martin Schrappe; G Janka-Schaub; Wolf-Dieter Ludwig; Jochen Harbott; Fritz H Lampert
Detection of hyperdiploid karyotypes (>50 chromosomes) in childhood acute lymphoblastic leukemia (ALL) using fluorescence in situ hybridization (FISH).
Leukemia 1998;12(3):427-33.
1998: Sabrina Tosi; Giovanni Giudici; G Mosna; Jochen Harbott; G Specchia; G Grosveld; Enrica Privitera; Lyndal Kearney; Andrea Biondi; Giovanni Cazzaniga
Identification of new partner chromosomes involved in fusions with the ETV6 (TEL) gene in hematologic malignancies.
Genes, chromosomes & cancer 1998;21(3):223-9.
1997: Jochen Harbott; Susanne Viehmann; Arndt Borkhardt; Günter Henze; Fritz H Lampert
Incidence of TEL/AML1 fusion gene analyzed consecutively in children with acute lymphoblastic leukemia in relapse.
Blood 1997;90(12):4933-7.
1997: Arndt Borkhardt; Giovanni Cazzaniga; Susanne Viehmann; M G Valsecchi; Wolf-Dieter Ludwig; L Burci; S Mangioni; Martin Schrappe; Hansjörg Riehm; Fritz H Lampert; G Basso; G Masera; Jochen Harbott; A Biondi
Incidence and clinical relevance of TEL/AML1 fusion genes in children with acute lymphoblastic leukemia enrolled in the German and Italian multicenter therapy trials. Associazione Italiana Ematologia Oncologia Pediatrica and the Berlin-Frankfurt-Münster Study Group.
Blood 1997;90(2):571-7.
1997: Charlotte M Niemeyer; M Arico; Giuseppe Basso; Andrea Biondi; A Cantu Rajnoldi; Ursula Creutzig; O Haas; Jochen Harbott; Henrik Hasle; Gitte B Kerndrup; Franco Locatelli; G Mann; B Stollmann-Gibbels; E T van't Veer-Korthof; Elisabeth R van Wering; Martin Zimmermann
Chronic myelomonocytic leukemia in childhood: a retrospective analysis of 110 cases. European Working Group on Myelodysplastic Syndromes in Childhood (EWOG-MDS)
Blood 1997;89(10):3534-43.
1997: Arndt Borkhardt; Roland Repp; Oskar A Haas; Thomas Leis; Jochen Harbott; Joachim Kreuder; J Hammermann; T Henn; Fritz H Lampert
Cloning and characterization of AFX, the gene that fuses to MLL in acute leukemias with a t(X;11)(q13;q23).
Oncogene 1997;14(2):195-202.
1996: Ursula Creutzig; J Ritter; Josef Vormoor; Wolf-Dieter Ludwig; C Niemeyer; I Reinisch; B Stollmann-Gibbels; Martin Zimmermann; Jochen Harbott
Myelodysplasia and acute myelogenous leukemia in Down's syndrome. A report of 40 children of the AML-BFM Study Group.
Leukemia 1996;10(11):1677-86.
1996: S Schlieben; Arndt Borkhardt; I Reinisch; J Ritterbach; Johannes W G Janssen; Richard Ratei; Martin Schrappe; Roland Repp; Martin Zimmermann; Hartmut Kabisch; Gritta E Janka-Schaub; C R Bartram; Wolf-Dieter Ludwig; Hansjörg Riehm; Fritz H Lampert; Jochen Harbott
Incidence and clinical outcome of children with BCR/ABL-positive acute lymphoblastic leukemia (ALL). A prospective RT-PCR study based on 673 patients enrolled in the German pediatric multicenter therapy trials ALL-BFM-90 and CoALL-05-92.
Leukemia 1996;10(6):957-63.
1996: S Tosi; Jochen Harbott; O A Haas; A Douglas; D M Hughes; F M Ross; Andrea Biondi; Stephen W Scherer; Lyndal Kearney
Classification of deletions and identification of cryptic translocations involving 7q by fluorescence in situ hybridization (FISH).
Leukemia 1996;10(4):644-9.
1995: U Creutzig; Jochen Harbott; C Sperling; J Ritter; M Zimmermann; Helmut Löffler; Hansjörg Riehm; G Schellong; Wolf-Dieter Ludwig
Clinical significance of surface antigen expression in children with acute myeloid leukemia: results of study AML-BFM-87.
Blood 1995;86(8):3097-108.
1995: A Borkhardt; S Brettreich; Arndt Borkhardt; Roland Repp; Jochen Harbott; Joachim Kreuder; Fritz H Lampert
Low frequency of RAS gene mutations and absence of mutations within the FLR exon of NF1 in patients with therapy-related leukemias.
Leukemia 1995;9(10):1790-1.
1995: Ursula Creutzig; J Ritter; Wolf-Dieter Ludwig; C Niemeyer; I Reinisch; B Stollmann-Gibbels; M Zimmermann; Jochen Harbott
[Acute myeloid leukemia in children with Down syndrome].
Klinische Pädiatrie 1995;207(4):136-44.
1995: C Sperling; Thomas Büchner; U Creutzig; J Ritter; Jochen Harbott; Christa Fonatsch; C Sauerland; M Mielcarek; G Maschmeyer; Helmut Löffler
Clinical, morphologic, cytogenetic and prognostic implications of CD34 expression in childhood and adult de novo AML.
Leukemia & lymphoma 1995;17(5-6):417-26.
1995: M M Seyger; J Ritterbach; U Creutzig; A K Gnekow; U Göbel; Norbert Graf; Alfred Reiter; Fritz H Lampert; Jochen Harbott
12q13, a new recurrent breakpoint in acute non-lymphoblastic leukemia.
Cancer genetics and cytogenetics 1995;80(1):23-8.
1995: K Nishida; J Ritterbach; Roland Repp; Jochen Harbott; Fritz H Lampert
Characterization of chromosome 8 abnormalities by fluorescence in situ hybridization in childhood B-acute lymphoblastic leukemia/non-Hodgkin lymphoma.
Cancer genetics and cytogenetics 1995;79(1):8-14.
1995: Roland Repp; Arndt Borkhardt; E Haupt; Joachim Kreuder; S Brettreich; J Hammermann; K Nishida; Jochen Harbott; Fritz H Lampert
Detection of four different 11q23 chromosomal abnormalities by multiplex-PCR and fluorescence-based automatic DNA-fragment analysis.
Leukemia 1995;9(1):210-5.
1994: Johannes W G Janssen; W D Ludwig; Arndt Borkhardt; U Spadinger; H Rieder; C Fonatsch; D K Hossfeld; Jochen Harbott; A S Schulz; Roland Repp
Pre-pre-B acute lymphoblastic leukemia: high frequency of alternatively spliced ALL1-AF4 transcripts and absence of minimal residual disease during complete remission.
Blood 1994;84(11):3835-42.
1994: S Tosi; J Ritterbach; O Maglia; Jochen Harbott; Hansjörg Riehm; Giuseppe Masera; Andrea Biondi; Fritz H Lampert
Double target in situ hybridization applied to the study of numerical aberrations in childhood acute lymphoblastic leukemia.
Cancer genetics and cytogenetics 1994;73(2):103-8.
1994: Frank Griesinger; H Elfers; Wolf-Dieter Ludwig; M Falk; Harald Rieder; Jochen Harbott; Fritz H Lampert; Barbara Heinze; Dieter Hoelzer; Eckhard Thiel
Detection of HRX-FEL fusion transcripts in pre-pre-B-ALL with and without cytogenetic demonstration of t(4;11).
Leukemia 1994;8(4):542-8.
1993: S Izraeli; T Henn; H Strobl; W D Ludwig; Heinrich Kovar; Oskar A Haas; Jochen Harbott; C R Bartram; Helmut Gadner; Thomas Lion
Expression of identical E2A/PBX1 fusion transcripts occurs in both pre-B and early pre-B immunological subtypes of childhood acute lymphoblastic leukemia.
Leukemia 1993;7(12):2054-6.
1993: L Li; J Ritterbach; Jochen Harbott; W Schroyens; Jürgen Lohmeyer; H Pralle; Fritz H Lampert
Blastic phase chronic myeloid leukemia with a four-break rearrangement: t(11;9)(9;22)(q23;p22q34;q11).
Cancer genetics and cytogenetics 1993;68(2):131-4.
1993: Arndt Borkhardt; Roland Repp; Jochen Harbott; M Lakomek; Johannes W G Janssen; S Schlieben; C R Bartram; Fritz H Lampert
BCR-ABL rearrangement in a child with acute myelogenous leukaemia without a Philadelphia chromosome.
British journal of haematology 1993;84(2):341-2.
1993: S Izraeli; J W Janssen; Oskar A Haas; Jochen Harbott; F Brok-Simoni; J U Walther; Heinrich Kovar; T Henn; W D Ludwig; A Reiter
Detection and clinical relevance of genetic abnormalities in pediatric acute lymphoblastic leukemia: a comparison between cytogenetic and polymerase chain reaction analyses.
Leukemia 1993;7(5):671-8.
1993: Arndt Borkhardt; Roland Repp; Jochen Harbott; Joachim Kreuder; Fritz H Lampert
Quantification of leukaemic cells based on heteroduplex formation of tal-1 gene sequences after PCR coamplification.
British journal of haematology 1993;83(1):39-44.
1993: Wolf-Dieter Ludwig; Jochen Harbott; Claus R Bartram; B Komischke; C Sperling; J V Teichmann; H Seibt-Jung; M Notter; E Odenwald; A Nehmer
Incidence and prognostic significance of immunophenotypic subgroups in childhood acute lymphoblastic leukemia: experience of the BFM study 86.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():269-82.
1993: Jochen Harbott; J Ritterbach; Wolf-Dieter Ludwig; C R Bartram; Alfred Reiter; Fritz H Lampert
Clinical significance of cytogenetic studies in childhood acute lymphoblastic leukemia: experience of the BFM trials.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():123-32.
1993: Wolfgang Hiddemann; Jochen Harbott; Wolf-Dieter Ludwig; J Ritter; A Nehmer; A Reiter; A Kolkmeyer; Timothy J Laing; H Riehm
DNA aneuploidy in childhood acute lymphoblastic leukemia: relation to clinical determinants and prognosis within four consecutive BFM trials.
Recent results in cancer research. Fortschritte der Krebsforschung. Progrès dans les recherches sur le cancer 1993;131():113-21.
1992: Alfred Reiter; Martin Schrappe; Wolf-Dieter Ludwig; F Lampert; Jochen Harbott; Günter Henze; C M Niemeyer; Helmut Gadner; S Müller-Weihrich; J Ritter
Favorable outcome of B-cell acute lymphoblastic leukemia in childhood: a report of three consecutive studies of the BFM group.
Blood 1992;80(10):2471-8.
1992: Josef Vormoor; J Ritter; Ursula Creutzig; Joachim Boos; P Heyen; Wolf-Dieter Ludwig; Jochen Harbott; Helmut Löffler; Günther Schellong
Acute myelogenous leukaemia in children under 2 years--experiences of the West German AML studies BFM-78, -83 and -87. AML-BFM Study Group.
The British journal of cancer. Supplement 1992;18():S63-7.
1992: Fritz H Lampert; Jochen Harbott; J Ritterbach
Cytogenetic findings in acute leukaemias of infants.
The British journal of cancer. Supplement 1992;18():S20-2.
1992: Thomas Lion; O A Haas; Jochen Harbott; E Bannier; J Ritterbach; M Jankovic; Franz-Martin Fink; A Stojimirovic; J Herrmann; Hansjörg Riehm
The translocation t(1;22)(p13;q13) is a nonrandom marker specifically associated with acute megakaryocytic leukemia in young children.
Blood 1992;79(12):3325-30.
1992: Arndt Borkhardt; Roland Repp; Jochen Harbott; C Keller; F Berner; J Ritterbach; Fritz H Lampert
Frequency and DNA sequence of tal-1 rearrangement in children with T-cell acute lymphoblastic leukemia.
Annals of hematology 1992;64(6):305-8.
1991: Fritz H Lampert; Jochen Harbott; J Ritterbach; G Schellong; J Ritter; U Creutzig; Hansjörg Riehm; Alfred Reiter
Karyotypes in acute childhood leukemias may lose prognostic significance with more intensive and specific chemotherapy.
Cancer genetics and cytogenetics 1991;54(2):277-9.
1991: Fritz H Lampert; Jochen Harbott; J Ritterbach
[Chromosome aberrations in acute leukemia in childhood: analysis of 1009 patients].
Klinische Pädiatrie 1991;203(4):311-8.
1991: J Maurer; Johannes W G Janssen; Eckhard Thiel; J van Denderen; Wolf-Dieter Ludwig; U Aydemir; Barbara Heinze; Christa Fonatsch; Jochen Harbott; A Reiter
Detection of chimeric BCR-ABL genes in acute lymphoblastic leukaemia by the polymerase chain reaction.
Lancet 1991;337(8749):1055-8.
1990: Wolf-Dieter Ludwig; Eckhard Thiel; U Köller; Claus R Bartram; Jochen Harbott; J V Teichmann; H Seibt-Jung; U Creutzig; J Ritter; Hansjörg Riehm
Incidence and clinical implications of acute hybrid leukemia in childhood.
Haematology and blood transfusion 1990;33():516-22.
1990: Ursula Creutzig; G Niederbiermann; J Ritter; Jochen Harbott; Helmut Löffler; Günther Schellong
Prognostic significance of eosinophilia in acute myelomonocytic leukemia in relation to induction treatment.
Haematology and blood transfusion 1990;33():226-32.
1990: J Ritterbach; Jochen Harbott; J Ritter; Fritz H Lampert
Chromosomal aberrations in childhood acute nonlymphoblastic leukemia.
Haematology and blood transfusion 1990;33():153-6.
1990: Jochen Harbott; J Ritterbach; Gritta E Janka-Schaub; Wolf-Dieter Ludwig; Alfred Reiter; Hansjörg Riehm; Fritz H Lampert
Cytogenetics of childhood acute lymphoblastic leukemia in multicenter trials.
Haematology and blood transfusion 1990;33():451-8.
1989: U Köller; Oskar A Haas; Wolf-Dieter Ludwig; Claus R Bartram; Jochen Harbott; R Panzer-Grümayer; T Hansen-Hagge; J Ritter; U Creutzig; Walter Knapp
Phenotypic and genotypic heterogeneity in infant acute leukemia. II. Acute nonlymphoblastic leukemia.
Leukemia 1989;3(10):708-14.
1989: Wolf-Dieter Ludwig; Claus R Bartram; Jochen Harbott; U Köller; Oskar A Haas; T Hansen-Hagge; G Heil; H Seibt-Jung; J V Teichmann; J Ritter
Phenotypic and genotypic heterogeneity in infant acute leukemia. I. Acute lymphoblastic leukemia.
Leukemia 1989;3(6):431-9.
1989: Claus R Bartram; W D Ludwig; W Hiddemann; J Lyons; M Buschle; J Ritter; Jochen Harbott; A Fröhlich; Johannes W G Janssen
Acute myeloid leukemia: analysis of ras gene mutations and clonality defined by polymorphic X-linked loci.
Leukemia 1989;3(4):247-56.
1989: Jochen Harbott; J Ritterbach; Fritz H Lampert
Leukemia cytogenetics in children: results of the German therapy studies.
Haematology and blood transfusion 1989;32():121-6.
1988: Wolf-Dieter Ludwig; Claus R Bartram; J Ritter; A Raghavachar; W Hiddemann; G Heil; Jochen Harbott; H Seibt-Jung; J V Teichmann; Hansjörg Riehm
Ambiguous phenotypes and genotypes in 16 children with acute leukemia as characterized by multiparameter analysis.
Blood 1988;71(6):1518-28.
1988: Fritz H Lampert; Jochen Harbott; J Ritterbach; Wolf-Dieter Ludwig; C Fonatsch; D Schwamborn; B Stier; A Gnekow; V Gerein; B Stollmann
T-cell acute childhood lymphoblastic leukemia with chromosome 14 q 11 anomaly: a morphologic, immunologic, and cytogenetic analysis of 10 patients.
Blut 1988;56(3):117-23.
1988: B Rudolph; Jochen Harbott; Fritz H Lampert
Fragile sites and neuroblastoma: fragile site at 1p13.1 and other points on lymphocyte chromosomes from patients and family members.
Cancer genetics and cytogenetics 1988;31(1):83-94.
1987: Fritz H Lampert; Jochen Harbott; Wolf-Dieter Ludwig; C R Bartram; J Ritter; V Gerein; M Neidhardt; R Mertens; Norbert Graf; H Riehm
Acute leukemia with chromosome translocation (4;11): 7 new patients and analysis of 71 cases.
Blut 1987;54(6):325-35.
1986: Jochen Harbott; R Engel; V Gerein; D Schwamborn; R Rudolph; Fritz H Lampert
(11; 14) translocation in three boys with acute lymphoblastic leukemia of T-cell immunophenotype.
Blut 1986;52(1):45-50.