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Brian Harbrecht

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Baochun Zhang; Jaganathan Lakshmanan; Ikenna Nweze; Brian G Harbrecht
Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression.
Benjamin R Reynolds; Jason L Sperry; Ernest E Billiar; Joseph Cuschieri; Raquel M Forsythe; Brian G Harbrecht; Ronald V Maier; Joseph P Minei; Ernest E Moore; Andrew B Peitzman
Hypothermia in massive transfusion: have we been paying enough attention to it?
Matthew C Bozeman; Robert M Cannon; Glen A Franklin; Frank B Miller; J David Richardson; Jason W Smith; John M Trombold; Brian G Harbrecht
Use of computed tomography findings and contrast extravasation in predicting the need for embolization with pelvic fractures.

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2013: Baochun Zhang; Jaganathan Lakshmanan; Ikenna Nweze; Brian G Harbrecht
Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression.
Shock (Augusta, Ga.) 2013;39(1):70-6.
2012: Benjamin R Reynolds; Jason L Sperry; Ernest E Billiar; Joseph Cuschieri; Raquel M Forsythe; Brian G Harbrecht; Ronald V Maier; Joseph P Minei; Ernest E Moore; Andrew B Peitzman
Hypothermia in massive transfusion: have we been paying enough attention to it?
The journal of trauma and acute care surgery 2012;73(2):486-91.
2012: Matthew C Bozeman; Robert M Cannon; Glen A Franklin; Frank B Miller; J David Richardson; Jason W Smith; John M Trombold; Brian G Harbrecht
Use of computed tomography findings and contrast extravasation in predicting the need for embolization with pelvic fractures.
The American surgeon 2012;78(8):825-30.
2012: Ikenna C Nweze; Jason W Smith; Baochun Zhang; Carolyn M Klinge; Jaganathan Lakshmanan; Brian G Harbrecht
17β-Estradiol attenuates cytokine-induced nitric oxide production in rat hepatocyte.
The journal of trauma and acute care surgery 2012;73(2):408-12.
2012: Brian G Harbrecht
Predicting outcome in patients with acute liver failure: what works best?
Critical care medicine 2012;40(5):1666-7.
2012: Matthew D Neal; Andrew B Peitzman; Timothy R Billiar; Mitchell J Cohen; Joseph Cuschieri; Brian G Harbrecht; Marcus K Hoffman; Ronald V Maier; Joseph P Minei; Ernest E Moore; Jason L Sperry
Crystalloid to packed red blood cell transfusion ratio in the massively transfused patient: when a little goes a long way.
The journal of trauma and acute care surgery 2012;72(4):892-8.
2012: Brian G Harbrecht
Head of bed elevation and ventilator-associated pneumonia.
Respiratory care 2012;57(4):659-60.
2012: Robert M Cannon; Glen A Franklin; Brian G Harbrecht; Frank B Miller; Jason W Smith; J David Richardson
Flail chest injury: are we making any progress?
The American surgeon 2012;78(4):398-402.
2012: Joseph P Minei; Lyle L Moldawer; Ernest E Moore; Grant E O'Keefe; Jason Sperry; Ronald G Tompkins; Michael A West; Mitchell J Cohen; Joseph Cuschieri; Brian G Harbrecht; Ronald V Maier
The changing pattern and implications of multiple organ failure after blunt injury with hemorrhagic shock.
Critical care medicine 2012;40(4):1129-35.
2012: Brian G Harbrecht; Frank B Miller; Robert M Shirley; Jason W Smith; Glen A Franklin; J David Richardson
Statewide experience with Clostridium difficile colitis in academic and non-academic medical centers.
Surgical infections 2012;13(2):88-92.
2012: Benjamin C Kautza; Ronald V Maier; Joseph P Minei; Ernest E Moore; Andrew B Peitzman; Jason L Sperry; Timothy R Billiar; Scott C Brackenridge; Mitchell J Cohen; Joseph Cuschieri; Brian G Harbrecht
Changes in massive transfusion over time: an early shift in the right direction?
The journal of trauma and acute care surgery 2012;72(1):106-11.
2011: Scott C Brakenridge; Joseph Cuschieri; Alexander E Eastman; Richard M Golden; Brian G Harbrecht; Steven S Henley; T Michael Kashner; Ronald V Maier; Joseph P Minei; Ernest E Moore; Herb A Phelan; Jason L Sperry
Early blood product and crystalloid volume resuscitation: risk association with multiple organ dysfunction after severe blunt traumatic injury.
The Journal of trauma 2011;71(2):299-305.
2011: Keith R Miller; Vance L Smith; Christy M Lawson; Brian G Harbrecht
Carbohydrate provision in the era of tight glucose control.
Current gastroenterology reports 2011;13(4):388-94.
2011: Jason W Smith; Glen A Franklin; Brian G Harbrecht; J David Richardson
Early VATS for blunt chest trauma: a management technique underutilized by acute care surgeons.
The Journal of trauma 2011;71(1):102-5; discussion 105-7.
2011: Rebecca D Edmonds; Joseph Cuschieri; Joseph P Minei; Matthew R Rosengart; Ronald V Maier; Brian G Harbrecht; Timothy R Billiar; Andrew B Peitzman; Ernest E Moore; Jason L Sperry
Body adipose content is independently associated with a higher risk of organ failure and nosocomial infection in the nonobese patient postinjury.
The Journal of trauma 2011;70(2):292-8.
2010: Glen A Franklin; Ariel P Santos; Jason W Smith; Susan Galbraith; Brian G Harbrecht; R Neal Garrison
Optimization of donor management goals yields increased organ use.
The American surgeon 2010;76(6):587-94.
2010: Brian G Harbrecht; Jason W Smith; Glen A Franklin; Frank B Miller; J David Richardson
Decreasing regional neurosurgical workforce-a blueprint for disaster.
The Journal of trauma 2010;68(6):1367-72; discussion 1372-4.
2010: Jason W Smith; R Neal Garrison; Paul J Matheson; Glen A Franklin; Brian G Harbrecht; J David Richardson
Direct peritoneal resuscitation accelerates primary abdominal wall closure after damage control surgery.
Journal of the American College of Surgeons 2010;210(5):658-64, 664-7.
2010: Guiying Hong; Baochun Zhang; Brian G Harbrecht
Cyclic AMP inhibits IL-1beta plus IFNgamma-induced NF-kappaB translocation in hepatocytes by a PKA independent mechanism.
The Journal of surgical research 2010;159(1):565-71.
2009: Maya Leggett; Brian G Harbrecht
Glucose control and its implications for the general surgeon.
The American surgeon 2009;75(11):1031-5.
2009: Brian G Harbrecht; Glen A Franklin; Jason W Smith; David S Foley; Frank B Miller; J David Richardson
Management differences for pediatric solid organ injuries in a rural state.
The American surgeon 2009;75(8):725-9.
2009: Gregory A Watson; Jason L Sperry; Matthew R Rosengart; Joseph P Minei; Brian G Harbrecht; Ernest E Moore; Joseph Cuschieri; Ronald V Maier; Timothy R Billiar; Andrew B Peitzman
Fresh frozen plasma is independently associated with a higher risk of multiple organ failure and acute respiratory distress syndrome.
The Journal of trauma 2009;67(2):221-7; discussion 228-30.
2009: Brian G Harbrecht; Edgar Delgado; Raymond P Tuttle; Mark H Cohen-Melamed; Melissa I Saul; Cynthia A Valenta
Improved outcomes with routine respiratory therapist evaluation of non-intensive-care-unit surgery patients.
Respiratory care 2009;54(7):861-7.
2009: J David Richardson; Glen Franklin; Ariel Santos; Brian G Harbrecht; Dan Danzl; Royce Coleman; Jason Smith; Frank Miller; Kelly McMasters
Effective triage can ameliorate the deleterious effects of delayed transfer of trauma patients from the emergency department to the ICU.
Journal of the American College of Surgeons 2009;208(5):671-8; discussion 678-81.
2009: Brady T Harris; Glen A Franklin; Brian G Harbrecht; J David Richardson
Impact of hollow viscus injuries on outcome of abdominal gunshot wounds.
The American surgeon 2009;75(5):378-84.
2009: Brian G Harbrecht; Mladen Djurasovic
Thoracolumbar spine trauma: diagnostic and therapeutic considerations for the general surgeon.
The American surgeon 2009;75(3):191-6.
2008: Matthew J Sena; Garth H Utter; Joseph Cuschieri; Ronald V Maier; Ronald G Tompkins; Brian G Harbrecht; Ernest E Moore; Grant E O'Keefe
Early supplemental parenteral nutrition is associated with increased infectious complications in critically ill trauma patients.
Journal of the American College of Surgeons 2008;207(4):459-67.
2008: Joseph Cuschieri; Brad Freeman; Grant O'Keefe; Brian G Harbrecht; Paul E Bankey; Jeffrey L Johnson; Joseph P Minei; Jason Sperry; Michael West; Avery B Nathens; Ernest E Moore; Ronald V Maier
Inflammation and the host response to injury a large-scale collaborative project: patient-oriented research core standard operating procedure for clinical care X. Guidelines for venous thromboembolism prophylaxis in the trauma patient.
The Journal of trauma 2008;65(4):944-50.
2008: W Patrick Klapheke; Glen A Franklin; David S Foley; Steven R Casos; Brian G Harbrecht; J David Richardson
Blunt liver injury in children and adults: is there really a difference?
The American surgeon 2008;74(9):798-801.
2008: Vishal Bansal; Eric C Wu; Christopher Compton; Raquel M Forsythe; Vaishali D Schuchert; Brian G Harbrecht; Ellen D Dillavou
Successful endovascular repair of a ruptured aortic pseudoaneurysm after swallowing sulfuric acid.
The Journal of trauma 2008;65(2):470-2.
2008: Brian G Harbrecht; Matthew R Rosengart; Kathy Bukauskas; Mazen S Zenati; J Wallis Marsh; David A Geller
Assessment of transcutaneous bilirubinometry in hospitalized adults.
Journal of the American College of Surgeons 2008;206(3):1129-36.
2008: Yinna Wang; Baochun Zhang; Ximei Peng; Michele Perpetua; Brian G Harbrecht
Bcl-xL prevents staurosporine-induced hepatocyte apoptosis by restoring protein kinase B/mitogen-activated protein kinase activity and mitochondria integrity.
Journal of cellular physiology 2008;215(3):676-83.
2008: Brian G Harbrecht; Glen A Franklin; Frank B Miller; J David Richardson
Is splenectomy after trauma an endangered species?
The American surgeon 2008;74(5):410-2.
2008: Brian G Harbrecht
Control of glucose after injury.
The American surgeon 2008;74(3):199-200.
2008: Jason L Sperry; Randall S Friese; Heidi Frankel; Michael A West; Joseph Cuschieri; Ernest E Moore; Brian G Harbrecht; Andrew B Peitzman; Timothy R Billiar; Ronald V Maier; Daniel G Remick; Joseph P Minei
Male gender is associated with excessive IL-6 expression following severe injury.
The Journal of trauma 2008;64(3):572-8; discussion 578-9.
2008: Jason L Sperry; Joseph P Minei; Heidi Frankel; Michael A West; Brian G Harbrecht; Ernest E Moore; Ronald V Maier; Ram Nirula
Early use of vasopressors after injury: caution before constriction.
The Journal of trauma 2008;64(1):9-14.
2007: Michael B Shapiro; Michael A West; Avery B Nathens; Brian G Harbrecht; Frederick A Moore; Paul E Bankey; Brad Freeman; Jeffrey L Johnson; Bruce A McKinley; Joseph P Minei; Ernest E Moore; Ronald V Maier
V. Guidelines for sedation and analgesia during mechanical ventilation general overview.
The Journal of trauma 2007;63(4):945-50.
2007: Brian G Harbrecht; Joseph P Minei; Michael B Shapiro; Avery B Nathens; Ernest E Moore; Michael A West; Paul E Bankey; Joseph Cuschieri; Jeffrey L Johnson; Ronald V Maier
Inflammation and the host response to injury, a large-scale collaborative project: patient-oriented research core-standard operating procedures for clinical care: VI. Blood glucose control in the critically ill trauma patient.
The Journal of trauma 2007;63(3):703-8.
2007: Jose M Prince; Raghuveer Vallabhaneni; Mazen S Zenati; Steven J Hughes; Brian G Harbrecht; Kenneth K Lee; Andrew R Watson; Andrew B Peitzman; Timothy R Billiar; Matthew T Brown
Increased interactive format for Morbidity & Mortality conference improves educational value and enhances confidence.
Journal of surgical education 2007;64(5):266-72.
2007: Brian G Harbrecht; Matthew R Rosengart; Mazen S Zenati; Raquel M Forsythe; Andrew B Peitzman
Defining the contribution of renal dysfunction to outcome after traumatic injury.
The American surgeon 2007;73(8):836-40.
2007: Brian G Harbrecht; Sae Hee Ko; Gregory A Watson; Raquel M Forsythe; Matthew R Rosengart; Andrew B Peitzman
Angiography for blunt splenic trauma does not improve the success rate of nonoperative management.
The Journal of trauma 2007;63(1):44-9.
2007: Glen A Franklin; J David Richardson; Aaron L Brown; A Britton Christmas; Frank B Miller; Brian G Harbrecht; Eddy H Carrillo
Prevention of bile peritonitis by laparoscopic evacuation and lavage after nonoperative treatment of liver injuries.
The American surgeon 2007;73(6):611-6; discussion 616-7.
2007: Kris Siriratsivawong; Mazen S Zenati; Gregory A Watson; Brian G Harbrecht
Nonoperative management of blunt splenic trauma in the elderly: does age play a role?
The American surgeon 2007;73(6):585-9; discussion 590.
2007: Avery B Nathens; Megan K McMurray; Joseph Cuschieri; Emily A Durr; Ernest E Moore; Paul E Bankey; Brad Freeman; Brian G Harbrecht; Jeffrey L Johnson; Joseph P Minei; Bruce A McKinley; Frederick A Moore; Michael B Shapiro; Michael A West; Ronald G Tompkins; Ronald V Maier
The practice of venous thromboembolism prophylaxis in the major trauma patient.
The Journal of trauma 2007;62(3):557-62; discussion 562-3.
2007: Brian G Harbrecht; Mazen S Zenati; Juan B Ochoa; Juan C Puyana; Louis H Alarcon; Andrew B Peitzman
Evaluation of a 15-year experience with splenic injuries in a state trauma system.
Surgery 2007;141(2):229-38.
2006: Gregory A Watson; Matthew R Rosengart; Mazen S Zenati; Allan Tsung; Raquel M Forsythe; Andrew B Peitzman; Brian G Harbrecht
Nonoperative management of severe blunt splenic injury: are we getting better?
The Journal of trauma 2006;61(5):1113-8; discussion 1118-9.
2006: Michael A West; Michael B Shapiro; Avery B Nathens; Jeffrey L Johnson; Ernest E Moore; Joseph P Minei; Paul E Bankey; Brad Freeman; Brian G Harbrecht; Bruce A McKinley; Frederick A Moore; Ronald V Maier
Inflammation and the host response to injury, a large-scale collaborative project: Patient-oriented research core-standard operating procedures for clinical care. IV. Guidelines for transfusion in the trauma patient.
The Journal of trauma 2006;61(2):436-9.
2006: Frederick A Moore; Bruce A McKinley; Ernest E Moore; Avery B Nathens; Michael West; Michael B Shapiro; Paul E Bankey; Brad Freeman; Brian G Harbrecht; Jeffrey L Johnson; Joseph P Minei; Ronald V Maier
Inflammation and the Host Response to Injury, a large-scale collaborative project: patient-oriented research core--standard operating procedures for clinical care. III. Guidelines for shock resuscitation.
The Journal of trauma 2006;61(1):82-9.
2006: Joseph P Minei; Avery B Nathens; Michael West; Brian G Harbrecht; Ernest E Moore; Michael B Shapiro; Paul E Bankey; Jeffrey L Johnson; Brad Freeman; Bruce A McKinley; Frederick A Moore; Ronald V Maier
Inflammation and the Host Response to Injury, a Large-Scale Collaborative Project: patient-oriented research core--standard operating procedures for clinical care. II. Guidelines for prevention, diagnosis and treatment of ventilator-associated pneumonia (VAP) in the trauma patient.
The Journal of trauma 2006;60(5):1106-13; discussion 1113.
2006: Runkuan Yang; Tomoyuki Harada; Kevin P Mollen; Jose M Prince; Ryan M Levy; Joshua A Englert; Margot Gallowitsch-Puerta; LiHong Yang; Huan Yang; Kevin Tracey; Brian G Harbrecht; Timothy R Billiar; Mitchell Fink
Anti-HMGB1 neutralizing antibody ameliorates gut barrier dysfunction and improves survival after hemorrhagic shock.
Molecular medicine (Cambridge, Mass.) 2006;12(4-6):105-14.
2006: Raquel M Forsythe; Brian G Harbrecht; Andrew B Peitzman
Blunt splenic trauma.
Scandinavian journal of surgery : SJS : official organ for the Finnish Surgical Society and the Scandinavian Surgical Society 2006;95(3):146-51.
2006: Brian G Harbrecht
Therapeutic use of nitric oxide scavengers in shock and sepsis.
Current pharmaceutical design 2006;12(27):3543-9.
2005: Brian G Harbrecht; Mazen S Zenati; Louis H Alarcon; Juan B Ochoa; Juan C Puyana; Vaishali D Schuchert; Andrew B Peitzman
Is outcome after blunt splenic injury in adults better in high-volume trauma centers?
The American surgeon 2005;71(11):942-8; discussion 948-9.
2005: Avery B Nathens; Jeffrey L Johnson; Joseph P Minei; Ernest E Moore; Michael Shapiro; Paul E Bankey; Brad Freeman; Brian G Harbrecht; Stephen F Lowry; Bruce A McKinley; Fredrick Moore; Michael West; Ronald V Maier
Inflammation and the Host Response to Injury, a large-scale collaborative project: Patient-Oriented Research Core--standard operating procedures for clinical care. I. Guidelines for mechanical ventilation of the trauma patient.
The Journal of trauma 2005;59(3):764-9.
2005: Andrew B Peitzman; Brian G Harbrecht; Luis Rivera; Brian Heil
Failure of observation of blunt splenic injury in adults: variability in practice and adverse consequences.
Journal of the American College of Surgeons 2005;201(2):179-87.
2005: Brian G Harbrecht
Is anything new in adult blunt splenic trauma?
American journal of surgery 2005;190(2):273-8.
2005: Brian G Harbrecht; Reginald F Frye; Mazen S Zenati; Robert A Branch; Andrew B Peitzman
Cytochrome P-450 activity is differentially altered in severely injured patients.
Critical care medicine 2005;33(3):541-6.
2005: Vishal Bansal; Kimberly M Syres; Valeriya Makarenkova; Ryan Brannon; Benjamin Matta; Brian G Harbrecht; Juan B Ochoa
Interactions between fatty acids and arginine metabolism: implications for the design of immune-enhancing diets.
JPEN. Journal of parenteral and enteral nutrition 2005;29(1 Suppl):S75-80.
2004: Brian G Harbrecht; Michele D Perpetua; Melissa Fulmer; Baochun Zhang
Glucagon regulates hepatic inducible nitric oxide synthesis in vivo.
Shock (Augusta, Ga.) 2004;22(2):157-62.
2004: Baochun Zhang; Michele D Perpetua; Melissa Fulmer; Brian G Harbrecht
JNK signaling involved in the effects of cyclic AMP on IL-1beta plus IFNgamma-induced inducible nitric oxide synthase expression in hepatocytes.
Cellular signalling 2004;16(7):837-46.
2004: Baochun Zhang; Shubing Liu; Michele D Perpetua; William H Walker; Brian G Harbrecht
Cytokines increase CRE binding but decrease CRE-mediated reporter activity in rat hepatocytes by increasing c-Jun.
Hepatology (Baltimore, Md.) 2004;39(5):1343-52.
2004: Brian G Harbrecht; Mazen S Zenati; Juan B Ochoa; Ricard N Townsend; Juan C Puyana; Mark A Wilson; Andrew B Peitzman
Management of adult blunt splenic injuries: comparison between level I and level II trauma centers.
Journal of the American College of Surgeons 2004;198(2):232-9.
2004: Christian Hierholzer; Jörg C Kalff; Timothy R Billiar; Anthony Bauer; David Tweardy; Brian G Harbrecht
Induced nitric oxide promotes intestinal inflammation following hemorrhagic shock.
American journal of physiology. Gastrointestinal and liver physiology 2004;286(2):G225-33.
2003: Baochun Zhang; Ye Liu; Brian G Harbrecht
Cyclic AMP regulate adenovirus mediated inducible nitric oxide synthase expression and CMV promoter activity in cultured hepatocytes.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2003;8(4):262-5.
2003: Christian Hierholzer; Timothy R Billiar; David Tweardy; Brian G Harbrecht
Reduced hepatic transcription factor activation and expression of IL-6 and ICAM-1 after hemorrhage by NO scavenging.
Archives of orthopaedic and trauma surgery 2003;123(2-3):55-9.
2002: Brian G Harbrecht; Mazen S Zenati; Howard Doyle; John McMichael; Ricard N Townsend; Keith D Clancy; Andrew B Peitzman
Hepatic dysfunction increases length of stay and risk of death after injury.
The Journal of trauma 2002;53(3):517-23.
2002: Mazen S Zenati; Timothy R Billiar; Ricard N Townsend; Andrew B Peitzman; Brian G Harbrecht
A brief episode of hypotension increases mortality in critically ill trauma patients.
The Journal of trauma 2002;53(2):232-6; discussion 236-7.
2002: Ramsey M Dallal; Brian G Harbrecht; Arthur J Boujoukas; Carl A Sirio; Linda M Farkas; Kenneth K Lee; Richard L Simmons
Fulminant Clostridium difficile: an underappreciated and increasing cause of death and complications.
Annals of surgery 2002;235(3):363-72.
2002: Christian Hierholzer; John M Menezes; Andreas Ungeheuer; Timothy R Billiar; David Tweardy; Brian G Harbrecht
A nitric oxide scavenger protects against pulmonary inflammation following hemorrhagic shock.
Shock (Augusta, Ga.) 2002;17(2):98-103.
2002: Rob Norris; Randy Woods; Brian G Harbrecht; Timothy Fabian; Michael Rhodes; John Morris; Timothy R Billiar; Anita P Courcoulas; Anthony O Udekwu; Christine Stinson; Andrew B Peitzman
TRISS unexpected survivors: an outdated standard?
The Journal of trauma 2002;52(2):229-34.
2002: John M Menezes; Christian Hierholzer; simon simon watkins; Timothy R Billiar; Andrew B Peitzman; Brian G Harbrecht
The modulation of hepatic injury and heat shock expression by inhibition of inducible nitric oxide synthase after hemorrhagic shock.
Shock (Augusta, Ga.) 2002;17(1):13-8.
2001: Andrew B Peitzman; Henri R Ford; Brian G Harbrecht; Douglas A Potoka; Ricard N Townsend
Injury to the spleen.
Current problems in surgery 2001;38(12):932-1008.
2001: Brian G Harbrecht; Howard Doyle; Keith D Clancy; Ricard N Townsend; Timothy R Billiar; Andrew B Peitzman
The impact of liver dysfunction on outcome in patients with multiple injuries.
The American surgeon 2001;67(2):122-6.
2001: Christian Hierholzer; Brian G Harbrecht; Timothy R Billiar; David Tweardy
Hypoxia-inducible factor-1 activation and cyclo-oxygenase-2 induction are early reperfusion-independent inflammatory events in hemorrhagic shock.
Archives of orthopaedic and trauma surgery 2001;121(4):219-22.
2000: Andrew B Peitzman; Brian Heil; L Rivera; M B Federle; Brian G Harbrecht; Keith D Clancy; M Croce; Blaine L Enderson; J A Morris; David Shatz; J Wayne Meredith; Juan B Ochoa; Samir M Fakhry; James G Cushman; Joseph P Minei; M McCarthy; Fred A Luchette; R Townsend; G Tinkoff; E F Block; S Ross; Eric R Frykberg; Richard M. Bell; F Davis; Leonard J Weireter; Michael B Shapiro
Blunt splenic injury in adults: Multi-institutional Study of the Eastern Association for the Surgery of Trauma.
The Journal of trauma 2000;49(2):177-87; discussion 187-9.
1999: J Menezes; Christian Hierholzer; simon simon watkins; VA Lyons; Andrew B Peitzman; Timothy R Billiar; David Tweardy; Brian G Harbrecht
A novel nitric oxide scavenger decreases liver injury and improves survival after hemorrhagic shock.
The American journal of physiology 1999;277(1 Pt 1):G144-51.
1999: Andrew B Peitzman; Anita P Courcoulas; C Stinson; Anthony O Udekwu; Timothy R Billiar; Brian G Harbrecht
Trauma center maturation: quantification of process and outcome.
Annals of surgery 1999;230(1):87-94.
1999: K Tsukada; LA Omert; J Menezes; Brian G Harbrecht; M Miyagishima; Christian Hierholzer; Timothy R Billiar
Neutrophil accumulation and damage to the gastric mucosa in resuscitated hemorrhagic shock is independent of inducible nitric oxide synthase.
Shock (Augusta, Ga.) 1999;11(5):319-24.
1998: NS Shah; Edward Kelly; Timothy R Billiar; H M Marshall; Brian G Harbrecht; Anthony O Udekwu; Andrew B Peitzman
Utility of clinical parameters of tissue oxygenation in a quantitative model of irreversible hemorrhagic shock.
Shock (Augusta, Ga.) 1998;10(5):343-6.
1998: Brian G Harbrecht; R J Moraca; Melissa I Saul; Anita P Courcoulas
Percutaneous endoscopic gastrostomy reduces total hospital costs in head-injured patients.
American journal of surgery 1998;176(4):311-4.
1998: Christian Hierholzer; Brian G Harbrecht; John M Menezes; J Kane; JD MacMicking; C F Nathan; Andrew B Peitzman; Timothy R Billiar; David Tweardy
Essential role of induced nitric oxide in the initiation of the inflammatory response after hemorrhagic shock.
The Journal of experimental medicine 1998;187(6):917-28.
1997: Brian G Harbrecht; B Wu; simon simon watkins; Timothy R Billiar; Andrew B Peitzman
Inhibition of nitric oxide synthesis during severe shock but not after resuscitation increases hepatic injury and neutrophil accumulation in hemorrhaged rats.
Shock (Augusta, Ga.) 1997;8(6):415-21.
1997: J Ou; Timothy M Carlos; simon simon watkins; J E Saavedra; L K Keefer; Young-Myeong Kim; Brian G Harbrecht; Timothy R Billiar
Differential effects of nonselective nitric oxide synthase (NOS) and selective inducible NOS inhibition on hepatic necrosis, apoptosis, ICAM-1 expression, and neutrophil accumulation during endotoxemia.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1997;1(5):404-16.
1997: Harry Marshall; A Capone; Anita P Courcoulas; Brian G Harbrecht; Timothy R Billiar; Anthony O Udekwu; Andrew B Peitzman
Effects of hemodilution on long-term survival in an uncontrolled hemorrhagic shock model in rats.
The Journal of trauma 1997;43(4):673-9.
1997: M Powell; Anita P Courcoulas; M Gardner; J Lynch; Brian G Harbrecht; Anthony O Udekwu; Timothy R Billiar; Michael P Federle; James V Ferris; Manuel P Meza; Andrew B Peitzman
Management of blunt splenic trauma: significant differences between adults and children.
Surgery 1997;122(4):654-60.
1997: Brian G Harbrecht; Young-Myeong Kim; E A Wirant; Richard L Simmons; Timothy R Billiar
Timing of prostaglandin exposure is critical for the inhibition of LPS- or IFN-gamma-induced macrophage NO synthesis by PGE2.
Journal of leukocyte biology 1997;61(6):712-20.
1997: Brian G Harbrecht; M Di Silvio; V Chough; Y M Kim; Richard L Simmons; Timothy R Billiar
Glutathione regulates nitric oxide synthase in cultured hepatocytes.
Annals of surgery 1997;225(1):76-87.
1996: Brian G Harbrecht; E M Wirant; Young-Myeong Kim; Timothy R Billiar
Glucagon inhibits hepatocyte nitric oxide synthesis.
Archives of surgery (Chicago, Ill. : 1960) 1996;131(12):1266-72.
1996: Brian G Harbrecht; Y M Kim; E M Wirant; R A Shapiro; T R Billiar
PGE2 and LTB4 inhibit cytokine-stimulated nitric oxide synthase type 2 expression in isolated rat hepatocytes.
Prostaglandins 1996;52(2):103-16.
1996: Edward Kelly; N Morgan; ES Woo; B Chetlin; Andrew B Peitzman; Brian G Harbrecht; Timothy R Billiar
Metallothionein and HSP-72 are induced in the liver by hemorrhagic shock and resuscitation but not by shock alone.
Surgery 1996;120(2):403-9; discussion 409-10.
1996: Anita P Courcoulas; E Kelly; Brian G Harbrecht
Laparoscopic cholecystectomy in the transplant population.
Surgical endoscopy 1996;10(5):516-9.
1995: Brian G Harbrecht; B Wu; simon simon watkins; Harry Marshall; Andrew B Peitzman; Timothy R Billiar
Inhibition of nitric oxide synthase during hemorrhagic shock increases hepatic injury.
Shock (Augusta, Ga.) 1995;4(5):332-7.
1995: Andrew B Peitzman; Timothy R Billiar; Brian G Harbrecht; Edward Kelly; Anthony O Udekwu; R L Simmons
Hemorrhagic shock.
Current problems in surgery 1995;32(11):925-1002.
1995: Brian G Harbrecht; E A McClure; Richard L Simmons; Timothy R Billiar
Prostanoids inhibit Kupffer cell nitric oxide synthesis.
The Journal of surgical research 1995;58(6):625-9.
1995: Brian G Harbrecht; Stewart C Wang; Richard L Simmons; Timothy R Billiar
Cyclic GMP and guanylate cyclase mediate lipopolysaccharide-induced Kupffer cell tumor necrosis factor-alpha synthesis.
Journal of leukocyte biology 1995;57(2):297-302.
1995: Brian G Harbrecht; Timothy R Billiar
The role of nitric oxide in Kupffer cell-hepatocyte interactions.
Shock (Augusta, Ga.) 1995;3(2):79-87.
1994: Brian G Harbrecht; M Di Silvio; Anthony J Demetris; Richard L Simmons; Timothy R Billiar
Tumor necrosis factor-alpha regulates in vivo nitric oxide synthesis and induces liver injury during endotoxemia.
Hepatology (Baltimore, Md.) 1994;20(4 Pt 1):1055-60.
1994: Brian G Harbrecht; J Stadler; Anthony J Demetris; Richard L Simmons; Timothy R Billiar
Nitric oxide and prostaglandins interact to prevent hepatic damage during murine endotoxemia.
The American journal of physiology 1994;266(6 Pt 1):G1004-10.
1993: Brian G Harbrecht; Timothy R Billiar; R D Curran; J Stadler; Richard L Simmons
Hepatocyte injury by activated neutrophils in vitro is mediated by proteases.
Annals of surgery 1993;218(2):120-8.
1993: J Stadler; Brian G Harbrecht; M Di Silvio; R D Curran; M L Jordan; Richard L Simmons; Timothy R Billiar
Endogenous nitric oxide inhibits the synthesis of cyclooxygenase products and interleukin-6 by rat Kupffer cells.
Journal of leukocyte biology 1993;53(2):165-72.
1992: J Stadler; B G Bentz; Brian G Harbrecht; M Di Silvio; R D Curran; Timothy R Billiar; Rosemary A Hoffman; Richard L Simmons
Tumor necrosis factor alpha inhibits hepatocyte mitochondrial respiration.
Annals of surgery 1992;216(5):539-46.
1992: Brian G Harbrecht; Timothy R Billiar; J Stadler; Anthony J Demetris; J B Ochoa; R D Curran; Richard L Simmons
Nitric oxide synthesis serves to reduce hepatic damage during acute murine endotoxemia.
Critical care medicine 1992;20(11):1568-74.
1992: Brian G Harbrecht; Timothy R Billiar; J Stadler; Anthony J Demetris; J Ochoa; R D Curran; Richard L Simmons
Inhibition of nitric oxide synthesis during endotoxemia promotes intrahepatic thrombosis and an oxygen radical-mediated hepatic injury.
Journal of leukocyte biology 1992;52(4):390-4.
1992: Timothy R Billiar; R D Curran; Brian G Harbrecht; J Stadler; D L Williams; J B Ochoa; M Di Silvio; Richard L Simmons; S A Murray
Association between synthesis and release of cGMP and nitric oxide biosynthesis by hepatocytes.
The American journal of physiology 1992;262(4 Pt 1):C1077-82.
1991: Timothy R Billiar; Jan M Langrehr; R D Curran; J B Ochoa; J Stadler; Brian G Harbrecht; Rosemary A Hoffman; Richard L Simmons
Two unique aspects of inducible .N = O synthase in liver cells and accessory cells: hepatic damage is minimized by hepatocyte .N = O production and immunoregulation is mediated by macrophage .N = O production.
Research in immunology 1991;142(7):584-6; discussion 598-9.
1991: J Stadler; R D Curran; J B Ochoa; Brian G Harbrecht; Rosemary A Hoffman; Richard L Simmons; Timothy R Billiar
Effect of endogenous nitric oxide on mitochondrial respiration of rat hepatocytes in vitro and in vivo.
Archives of surgery (Chicago, Ill. : 1960) 1991;126(2):186-91.
1990: Timothy R Billiar; R D Curran; Brian G Harbrecht; D J Stuehr; Anthony J Demetris; Richard L Simmons
Modulation of nitrogen oxide synthesis in vivo: NG-monomethyl-L-arginine inhibits endotoxin-induced nitrate/nitrate biosynthesis while promoting hepatic damage.
Journal of leukocyte biology 1990;48(6):565-9.
1990: R D Curran; Timothy R Billiar; D J Stuehr; J B Ochoa; Brian G Harbrecht; S G Flint; Richard L Simmons
Multiple cytokines are required to induce hepatocyte nitric oxide production and inhibit total protein synthesis.
Annals of surgery 1990;212(4):462-9; discussion 470-1.