FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Jürgen Harder

Research Profile

Chemicals & Drugs

Anatomy

Concepts & Ideas

Molecular Sequence Data

Procedures

Living Beings

Pseudomonas aeruginosa

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Disorders

Atopic Dermatitis

Co-author Network

Publications

TOP 3
Maren Simanski; Stefanie Wanner; Christopher Weidenmaier; Regine Gläser; Bente Köten; Ulf Meyer-Hoffert; Andreas Peschel; Jürgen Harder
Staphylococcus aureus subverts cutaneous defense by d-alanylation of teichoic acids.
Maren Simanski; Regine Gläser; Franziska Rademacher; Lena Schröder; Hanna Maria Schumacher; Jürgen Harder
IL-17A and IFN-γ Synergistically Induce RNase 7 Expression via STAT3 in Primary Keratinocytes.
Jürgen Harder; Jens-Michael Schröder; Regine Gläser
The skin surface as antimicrobial barrier: present concepts and future outlooks.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Jürgen Harder (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Maren Simanski; Stefanie Wanner; Christopher Weidenmaier; Regine Gläser; Bente Köten; Ulf Meyer-Hoffert; Andreas Peschel; Jürgen Harder
Staphylococcus aureus subverts cutaneous defense by d-alanylation of teichoic acids.
Experimental dermatology 2013;22(4):294-6.
2013: Maren Simanski; Regine Gläser; Franziska Rademacher; Lena Schröder; Hanna Maria Schumacher; Jürgen Harder
IL-17A and IFN-γ Synergistically Induce RNase 7 Expression via STAT3 in Primary Keratinocytes.
PloS one 2013;8(3):e59531.
2013: Jürgen Harder; Jens-Michael Schröder; Regine Gläser
The skin surface as antimicrobial barrier: present concepts and future outlooks.
Experimental dermatology 2013;22(1):1-5.
2012: Bente Köten; Ulf Meyer-Hoffert; Rainer Podschun; Christof von Eiff; Karsten Becker; Jürgen Harder; Regine Gläser
Susceptibility of Staphylococcus aureus bacteremia strains to different skin-derived antimicrobial proteins.
Archives of dermatological research 2012;304(8):633-7.
2012: Maren Simanski; Sarah Babucke; Leo Eberl; Jürgen Harder
Paraoxonase 2 acts as a quorum sensing-quenching factor in human keratinocytes.
The Journal of investigative dermatology 2012;132(9):2296-9.
2012: Maren Simanski; Regine Gläser; Bente Köten; Jens-Michael Schröder; Jürgen Harder
Antimicrobial RNases in cutaneous defense.
Journal of innate immunity 2012;4(3):241-7.
2011: Jens-Michael Jensen; Josef G Meingassner; Andreas Scherer; Thomas Schwarz; Anton Stütz; Kerstin Ahrens; Matthias Bräutigam; Regina Fölster-Holst; Regine Gläser; Jürgen Harder; Ehrhardt Proksch
Differential suppression of epidermal antimicrobial protein expression in atopic dermatitis and in EFAD mice by pimecrolimus compared to corticosteroids.
Experimental dermatology 2011;20(10):783-8.
2011: Martin Laudien; Stefanie Dressel; Jürgen Harder; Regine Gläser
Differential expression pattern of antimicrobial peptides in nasal mucosa and secretion.
Rhinology 2011;49(1):107-11.
2011: Kerstin Ahrens; Michael Schunck; Graziella-Francesca Podda; Josef G Meingassner; Anton Stuetz; Jens-Michael Schröder; Jürgen Harder; Ehrhardt Proksch
Mechanical and metabolic injury to the skin barrier leads to increased expression of murine β-defensin-1, -3, and -14.
The Journal of investigative dermatology 2011;131(2):443-52.
2010: Maren Simanski; Stefanie Dressel; Regine Gläser; Jürgen Harder
RNase 7 protects healthy skin from Staphylococcus aureus colonization.
The Journal of investigative dermatology 2010;130(12):2836-8.
2010: Stefanie Dressel; Jürgen Harder; Jesko Cordes; Maike Wittersheim; Ulf Meyer-Hoffert; Cord Sunderkötter; Regine Gläser
Differential expression of antimicrobial peptides in margins of chronic wounds.
Experimental dermatology 2010;19(7):628-32.
2010: Nina Himmerkus; Veit Vassen; Birte Sievers; Boeren Goerke; Qixian Shan; Jürgen Harder; Jens-Michael Schröder; Markus Bleich
Human beta-defensin-2 increases cholinergic response in colon epithelium.
Pflügers Archiv : European journal of physiology 2010;460(1):177-86.
2010: Jürgen Harder; Stefanie Dressel; Maike Wittersheim; Jesko Cordes; Ulf Meyer-Hoffert; Ulrich Mrowietz; Regina Fölster-Holst; Ehrhardt Proksch; Jens-Michael Schröder; Thomas Schwarz; Regine Gläser
Enhanced expression and secretion of antimicrobial peptides in atopic dermatitis and after superficial skin injury.
The Journal of investigative dermatology 2010;130(5):1355-64.
2009: Regine Gläser; Ulf Meyer-Hoffert; Jürgen Harder
[Antimicrobial peptides in atopic dermatitis. A paradigm shift?].
Der Hautarzt; Zeitschrift für Dermatologie, Venerologie, und verwandte Gebiete 2009;60(9):761-2.
2009: Zhihong Wu; Ulf Meyer-Hoffert; Katrin Reithmayer; Ralf Paus; Britta Hansmann; Yinghong He; Joachim Bartels; Regine Gläser; Jürgen Harder; Jens-Michael Schröder
Highly complex peptide aggregates of the S100 fused-type protein hornerin are present in human skin.
The Journal of investigative dermatology 2009;129(6):1446-58.
2009: Regine Gläser; Fatemeh Navid; Winfried Schuller; Christian Jantschitsch; Jürgen Harder; Jens Schröder; Agatha Schwarz; Thomas Schwarz
UV-B radiation induces the expression of antimicrobial peptides in human keratinocytes in vitro and in vivo.
The Journal of allergy and clinical immunology 2009;123(5):1117-23.
2009: Thomas C G Bosch; René Augustin; Friederike Anton-Erxleben; Sebastian Fraune; Georg Hemmrich; Holger Zill; Philip Rosenstiel; Gunnar Jacobs; Stefan Schreiber; Joachim Grötzinger; Mareike Stanisak; Joachim Grötzinger; Sascha Jung; Rainer Podschun; Joachim Bartels; Jürgen Harder; Jens Schröder
Uncovering the evolutionary history of innate immunity: the simple metazoan Hydra uses epithelial cells for host defence.
Developmental and comparative immunology 2009;33(4):559-69.
2009: Regine Gläser; Ulf Meyer-Hoffert; Jürgen Harder; Jesko Cordes; Maike Wittersheim; Julia Kobliakova; Regina Fölster-Holst; Ehrhardt Proksch; Jens Schröder; Thomas Schwarz
The antimicrobial protein psoriasin (S100A7) is upregulated in atopic dermatitis and after experimental skin barrier disruption.
The Journal of investigative dermatology 2009;129(3):641-9.
2009: Bente Köten; Maren Simanski; Regine Gläser; Rainer Podschun; Jens-Michael Schröder; Jürgen Harder
RNase 7 contributes to the cutaneous defense against Enterococcus faecium.
PloS one 2009;4(7):e6424.
2008: Henrik Suttmann; Margitta Retz; Friedrich Paulsen; Jürgen Harder; Ulrike Zwergel; Joern Kamradt; Bernd Wullich; Gerhard Unteregger; Michael Stöckle; Jan Lehmann
Antimicrobial peptides of the Cecropin-family show potent antitumor activity against bladder cancer cells.
BMC urology 2008;8():5.
2007: Jürgen Harder; Regine Gläser; Jens Schröder
The role and potential therapeutical applications of antimicrobial proteins in infectious and inflammatory diseases.
Endocrine, metabolic & immune disorders drug targets 2007;7(2):75-82.
2007: Noemi Moubayed; Michael Weichenthal; Jürgen Harder; Elke Wandel; Michael Sticherling; Regine Gläser
Psoriasin (S100A7) is significantly up-regulated in human epithelial skin tumours.
Journal of cancer research and clinical oncology 2007;133(4):253-61.
2007: Jürgen Harder; Regine Gläser; Jens Schröder
Human antimicrobial proteins effectors of innate immunity.
Journal of endotoxin research 2007;13(6):317-38.
2006: Bente Rudolph; Rainer Podschun; Hany Sahly; Sabine Schubert; Jens Schröder; Jürgen Harder
Identification of RNase 8 as a novel human antimicrobial protein.
Antimicrobial agents and chemotherapy 2006;50(9):3194-6.
2006: Jan Lehmann; Margitta Retz; Sukhvinder S Sidhu; Henrik Suttmann; Michael Sell; Friedrich Paulsen; Jürgen Harder; Gerhard Unteregger; Michael Stöckle
Antitumor activity of the antimicrobial peptide magainin II against bladder cancer cell lines.
European urology 2006;50(1):141-7.
2006: Arne Böhling; Sven O Hagge; Stefanie Roes; Rainer Podschun; Hany Sahly; Jürgen Harder; Jens Schröder; Joachim Grötzinger; Ulrich Seydel; Thomas Gutsmann
Lipid-specific membrane activity of human beta-defensin-3.
Biochemistry 2006;45(17):5663-70.
2006: Hany Sahly; Sabine Schubert; Jürgen Harder; Michael Kleine; Dorthe Sandvang; Uwe Ullmann; Jens Schröder; Rainer Podschun
Activity of human beta-defensins 2 and 3 against ESBL-producing Klebsiella strains.
The Journal of antimicrobial chemotherapy 2006;57(3):562-5.
2006: Eske Voss; Jan Wehkamp; Kai Wehkamp; Eduard F Stange; Jens Schröder; Jürgen Harder
NOD2/CARD15 mediates induction of the antimicrobial peptide human beta-defensin-2.
The Journal of biological chemistry 2006;281(4):2005-11.
2006: Kai Wehkamp; Lars Schwichtenberg; Jens Schröder; Jürgen Harder
Pseudomonas aeruginosa- and IL-1beta-mediated induction of human beta-defensin-2 in keratinocytes is controlled by NF-kappaB and AP-1.
The Journal of investigative dermatology 2006;126(1):121-7.
2005: Deike Varoga; Thomas Pufe; Jürgen Harder; Jens Schröder; Rolf Mentlein; Ulf Meyer-Hoffert; Mary B Goldring; Bernhard Tillmann; Joachim Hassenpflug; Friedrich Paulsen
Human beta-defensin 3 mediates tissue remodeling processes in articular cartilage by increasing levels of metalloproteinases and reducing levels of their endogenous inhibitors.
Arthritis and rheumatism 2005;52(6):1736-45.
2005: Jürgen Harder; Jens Schröder
Psoriatic scales: a promising source for the isolation of human skin-derived antimicrobial proteins.
Journal of leukocyte biology 2005;77(4):476-86.
2005: Regine Gläser; Jürgen Harder; Hans Lange; Joachim Bartels; Enno Christophers; Jens Schröder
Antimicrobial psoriasin (S100A7) protects human skin from Escherichia coli infection.
Nature immunology 2005;6(1):57-64.
2004: Deike Varoga; Thomas Pufe; Jürgen Harder; Ulf Meyer-Hoffert; Rolf Mentlein; Jens Schröder; Wolf Petersen; Bernhard Tillmann; Ehrhardt Proksch; Mary B Goldring; Friedrich P Paulsen
Production of endogenous antibiotics in articular cartilage.
Arthritis and rheumatism 2004;50(11):3526-34.
2004: Jan Wehkamp; Jürgen Harder; Michael Weichenthal; M Schwab; E Schäffeler; Miriam Schlee; Klaus R Herrlinger; A Stallmach; F Noack; P Fritz; Jens Schröder; Charles L Bevins; Klaus Fellermann; Eduard F Stange
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression.
Gut 2004;53(11):1658-64.
2004: Jan Wehkamp; Jürgen Harder; Kai Wehkamp; Birte Wehkamp-von Meissner; Miriam Schlee; Corinne Enders; Ulrich Sonnenborn; Sabine Nuding; Stig Bengmark; Klaus Fellermann; Jens Schröder; Eduard F Stange
NF-kappaB- and AP-1-mediated induction of human beta defensin-2 in intestinal epithelial cells by Escherichia coli Nissle 1917: a novel effect of a probiotic bacterium.
Infection and immunity 2004;72(10):5750-8.
2004: Jürgen Harder; Ulf Meyer-Hoffert; Kai Wehkamp; Lars Schwichtenberg; Jens Schröder
Differential gene induction of human beta-defensins (hBD-1, -2, -3, and -4) in keratinocytes is inhibited by retinoic acid.
The Journal of investigative dermatology 2004;123(3):522-9.
2004: Jens Eduard Meyer; Jürgen Harder; Tibor Görögh; Jan Bernd Weise; Sabine Schubert; Dirk Janssen; Steffen Maune
Human beta-defensin-2 in oral cancer with opportunistic Candida infection.
Anticancer research 2004;24(2B):1025-30.
2003: Jan Wehkamp; Jürgen Harder; Michael Weichenthal; Oliver Mueller; Klaus R Herrlinger; Klaus Fellermann; Jens M Schroeder; Eduard F Stange
Inducible and constitutive beta-defensins are differentially expressed in Crohn's disease and ulcerative colitis.
Inflammatory bowel diseases 2003;9(4):215-23.
2003: Hany Sahly; Sabine Schubert; Jürgen Harder; Peter Rautenberg; Uwe Ullmann; Jens Schröder; Rainer Podschun
Burkholderia is highly resistant to human Beta-defensin 3.
Antimicrobial agents and chemotherapy 2003;47(5):1739-41.
2002: Jürgen Harder; Jens Schröder
RNase 7, a novel innate immune defense antimicrobial protein of healthy human skin.
The Journal of biological chemistry 2002;277(48):46779-84.
2002: Jan Lehmann; Margitta Retz; Jürgen Harder; Matthias Krams; Udo Kellner; Julia Hartmann; Kerstin Hohgräwe; Uta Raffenberg; Martin Gerber; Tillmann Loch; Klaus Weichert-Jacobsen; Michael Stöckle
Expression of human beta-defensins 1 and 2 in kidneys with chronic bacterial infection.
BMC infectious diseases 2002;2():20.
2001: Anton Dunsche; Yahya Açil; Reiner Siebert; Jürgen Harder; Jens Schröder; Søren Jepsen
Expression profile of human defensins and antimicrobial proteins in oral tissues.
Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology 2001;30(3):154-8.
2001: Jürgen Harder; Joachim Bartels; Enno Christophers; Jens Schröder
Isolation and characterization of human beta -defensin-3, a novel human inducible peptide antibiotic.
The Journal of biological chemistry 2001;276(8):5707-13.
2000: Jens Eduard Meyer; Jürgen Harder; Tibor Görögh; Jens Schröder; Steffen Maune
[hBD-2 gene expression in nasal mucosa].
Laryngo- rhino- otologie 2000;79(7):400-3.
2000: Jürgen Harder; Ulf Meyer-Hoffert; Luis M Teran; Lars Schwichtenberg; Joachim Bartels; Steffen Maune; Jens Schröder
Mucoid Pseudomonas aeruginosa, TNF-alpha, and IL-1beta, but not IL-6, induce human beta-defensin-2 in respiratory epithelia.
American journal of respiratory cell and molecular biology 2000;22(6):714-21.
1999: Jens Schröder; Jürgen Harder
Human beta-defensin-2.
The international journal of biochemistry & cell biology 1999;31(6):645-51.
1998: Margitta Retz; Jan Lehmann; Christian Röder; B Plötz; Jürgen Harder; J Eggers; J Pauluschke; Holger Kalthoff; Michael Stöckle
Differential mucin MUC7 gene expression in invasive bladder carcinoma in contrast to uniform MUC1 and MUC2 gene expression in both normal urothelium and bladder carcinoma.
Cancer research 1998;58(24):5662-6.
1998: Oliver Wiedow; Jürgen Harder; Joachim Bartels; V Streit; Enno Christophers
Antileukoprotease in human skin: an antibiotic peptide constitutively produced by keratinocytes.
Biochemical and biophysical research communications 1998;248(3):904-9.
1997: Jürgen Harder; Reiner Siebert; Y Zhang; P Matthiesen; E Christophers; Brigitte Schlegelberger; Jens Schröder
Mapping of the gene encoding human beta-defensin-2 (DEFB2) to chromosome region 8p22-p23.1.
Genomics 1997;46(3):472-5.